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1 rminal region termed REKLES (for a conserved amino acid motif).
2 eptides containing a SRRxFLK 'twin-arginine' amino acid motif.
3 80, bound to HLA-C allotypes carrying either amino acid motif.
4 gion of the protein has a novel repeating 90-amino acid motif.
5 e conservation, redefining the D-box as a 12-amino acid motif.
6 repeats of this imperfectly conserved 11-mer amino acid motif.
7 plasmic proteins are glycosylated at a three amino acid motif.
8 pha-helical transmembrane domain a conserved amino acid motif.
9 s and glycosylate proteins at the same three amino acid motif.
10 oximately 100 amino acids) and conserved WXG amino acid motif.
11 sence of CDR3 fitting to an AGA(G(n))GG-like amino acid motif.
12 omain mapped the interaction to a minimal 12-amino-acid motif.
13 rchitecture of its coding sequence and novel amino acid motifs.
14 These domains are characterised by repeating amino acid motifs.
15 es bearing conserved SRRxFLK 'twin-arginine' amino acid motifs.
16 les, correlating in some cases with specific amino acid motifs.
19 3F3A and a commercial anti-Gp78 mAb to an 8-amino acid motif (533-541) in mouse Gp78 isoform 2 that
20 letion/point mutants elucidated a specific 4-amino acid motif (535IVVY538) essential for osteoclastog
21 ed beta-turn ((58)GVWGG(62)) followed by two amino acid motifs ((72)KRRN(75) and (78)TKAR(81)) that a
22 al CAAX (C=cysteine, A=aliphatic, X=terminal amino acid) motif, a substrate for posttranslational mod
23 breast carcinoma cells is determined by a 12-amino-acid motif (amino acids 313 to 325) within the PKC
24 terized by a series of 10 repeats of a seven amino acid motif and an unusually high number of histidi
25 vage at Site 1 does not depend on a specific amino acid motif and differs from cleavage at Site 2 by
26 Trefoil factor (TFF) peptides, with a 40-amino acid motif and including six conserved cysteine re
28 e furin cleavage site that extends the basic amino acid motif and multiple changes in the immunogenic
29 specifically to methylated DNA via a related amino acid motif and that can repress transcription.
33 d highly conserved functional nucleotide and amino acid motifs and positions across all (sub)genotype
34 n machinery, we defined specific subregions, amino acid motifs and protein binding partners involved
35 Y113 and Y128) fall within an identical five amino-acid motif and are shown to be phosphorylated upon
36 ng AT hooks bind A/T-rich DNA through a nine-amino-acid motif and are thought to co-regulate transcri
37 mmunodeficiency virus SIVmac(239) p6 to a 10-amino-acid motif and introduced this sequence into an in
39 ange of family members, related by conserved amino-acid motifs, and act as molecular binary switches
40 This activity is (a) mediated by the IGD amino acid motif; and (b) not expressed by (i.e., crypti
42 , and LPEAT, we believe that these conserved amino acid motifs are diagnostic for the acyltransferase
47 linked sites are associated with nonstandard amino acid motifs as a result of glycosylation by virus-
48 nserved cytoplasmic regions contain a common amino acid motif, Asn-Pro-Thr-Tyr, which has previously
49 hird, the S1 subunit possesses a distinctive amino acid motif at its carboxy terminus, including a te
51 ors and for human-like receptors, describing amino acid motifs at positions 190, 226 and 227 that pla
52 nal FAD synthetases, yet shorter and lacking amino acid motifs at the C terminus, were found by bioin
53 these H5N1 viruses possessed multiple basic amino acid motifs at the cleavage site, were HP for expe
57 e N-terminus of Dsh, we identify a short (21 amino acid) motif between the PDZ and DEP domains that i
58 mutagenesis demonstrated that a small basic amino acid motif (BIIa) in this region is essential for
63 PB1-F2-derived C-terminal peptide with this amino acid motif caused significantly greater weight los
64 ine, A is aliphatic amino acid, and X is any amino acid) motif (CCFV), suggesting that Wrch-1 may be
65 ither wild-type gB, mutant gB having the RGD amino acid motif changed to RAA, or K8.1 efficiently res
66 ion requires box B, a short highly conserved amino acid motif characteristic of BTG2/TOB family prote
67 g seven hydrophobic helical regions and a 17 amino acid motif characteristic of the R7G family of G-p
68 estriction-modification enzyme LlaGI reveals amino acid motifs characteristic of the Escherichia coli
70 otein contains 50 contiguous Gly-X-X triplet amino acid motifs characteristic of the structure of hum
71 obic amino acid, Y is tyrosine, and X is any amino acid) motif characteristic of several proteasome a
72 erall sequence identity, but do contain a 12-amino acid motif common to all enzymes that activate the
73 ealed that the final beta-strand contains an amino acid motif common to other beta-barrel outer membr
74 target sequences coding for highly conserved amino acid motifs covering a region of approximately 800
75 different from that of animal beta subunits, amino acid motifs critical for this catalytic activity a
77 of 29,038, and contains four copies of a 10-amino acid motif defining potential DNA-binding sites.
80 GF repeat/DHR domain, is an approximately 90-amino acid motif discovered in a recently identified fam
82 Many ERK1/2-interacting proteins contain amino acid motifs, e.g., DEF or D-motifs, which regulate
83 nuclear localization sequences (NLSs), short amino acids motifs enriched in Lys and Arg residues.
86 Peptide library analyses defined a preferred amino acid motif for ATM that permits clear distinctions
88 their binding sites are defined by conserved amino acid motifs, forming the structural basis for unde
89 enerate oligonucleotide based on a conserved amino acid motif found in all class A high-molecular-mas
90 domain of colicin E9 (the E9 DNase) is a 32 amino acid motif found in the H-N-H group of homing endo
92 In addition, several of the peptides contain amino acid motifs found in the G-H loop of the ephrin-B
93 domain, but rather is an uncharacterized 90 amino acid motif, found in both FCHo and SGIP proteins,
95 dicted size but are unified by the conserved amino acid motifs GGAI and FXXN repeated in the N-termin
96 n the RyRs has a predicted pore helix and an amino acid motif (GGGIG) similar to the selectivity filt
98 Thus, we show that one of the most common amino-acid motifs has spring properties that could be im
99 ersion of a previously described WDD-binding amino acid motif, here we show that this element is pres
100 two related proteins that contain a repeated amino acid motif homologous to the anti-angiogenic type
103 identified a role for a conserved polybasic amino acid motif in an N-terminal domain previously impl
104 Asn-X-X-X-X-Gly-Tyr motif of loop C and a 14 amino acid motif in apoplastic loop E, Thr-Gly-Ile/Thr-A
105 ted the presence of a highly conserved novel amino acid motif in avirulence proteins from three diffe
106 mmunication, we report that the conserved 11-amino acid motif in dematin52 and protein 4.2 contains a
108 planation for the presence of this conserved amino acid motif in hundreds of functionally diverse mem
109 We recently identified an N-terminal di-amino acid motif in NS1 that modulates protein targeting
110 Mutational analysis of a cyclin F-specific amino acid motif in the C-terminal region of Vif indicat
111 that hsc70 binds directly to a specific five-amino acid motif in the cargo protein for its autophagic
114 heir intron targets and that CRS2 binds a 22 amino acid motif in the COOH-terminal region of CAF2 tha
116 Here we show that a crucial Tyr-Ile-Asn-Met amino acid motif in the cytoplasmic tail of DAP10 couple
121 nding activity was finally localized to a 12-amino acid motif in the N-terminal CbpA by peptide mappi
122 2 domain combined with an exchange of a four amino acid motif in the R3 domain, could swap the pathwa
123 ell as in vitro binding assays revealed a 21-amino acid motif in the regulatory domain of SOS2 that i
124 We have identified a highly conserved 12-amino acid motif in the transcription factor Sall1 that
126 re, we report the identification of a unique amino acid motif in the vesicular GABA transporter (VGAT
128 rotein maturation and cleave at paired basic amino acid motifs in numerous cellular and viral glycopr
129 Alanine mutations to either of two dibasic amino acid motifs in the G2 cytoplasmic domain can also
133 ceptor-interacting LXXLL (L, leucine; X, any amino acid) motifs in PBP in a ligand-dependent manner.
134 ctors, the CAAX (where A indicates alipathic amino acid) motifs in the gamma1, gamma2, and gamma11 su
137 rgo through the recognition of short, linear amino-acid motifs in their cytoplasmic portions by vesic
140 The NS polyprotein revealed all typical CV amino acid motifs, including GXXGXGKT (NTPase), EYXEX (V
141 and confirmed the presence of four conserved amino acid motifs, including motif I, KXDG with lysine 1
142 sessing a single copy of the C1 domain, a 50-amino acid motif initially identified in protein kinase
147 residue and that the Ser-X-X-X-Ser (X is any amino acid) motif is obligatory for beta-catenin phospho
148 P and that this interaction requires a basic amino acid motif (KKPAKK) within the cytosolic region of
150 ORT), and by examining queried sequences for amino acid motifs known to serve critical roles in endoc
153 t amino acid residues, including a conserved amino acid motif located downstream of each of the NFATc
156 cture-function studies, we found that a YLGA amino-acid motif located near the extracellular N termin
158 ith TFIIB support the notion that this basic amino acid motif may influence the overall structure and
159 Sequence analyses indicate that the euAP1 amino acid motifs may have arisen via a translational fr
161 itor of Ran1/Pat1 kinase and contains a nine-amino-acid motif, Mei3-RKDIII, that resembles two region
162 t interacting molecules via an N-terminal 18 amino acid motif (MT elimination domain/MTED) that binds
164 the export of E. coli SecM is blocked, a 17 amino acid motif near the C terminus of the protein indu
165 stop codons on the mRNA via their conserved amino acid motifs (NIKS in eRF1 and SPF in RF2) and by t
166 ely charged aspartate residues within the 11 amino acid motif of FL trkB were mutated to examine the
167 o-valine change in the highly conserved YMDD amino acid motif of HIV-1 RT (M184V), which has been sho
169 lize the interaction to the C-terminal -TTPV amino acid motif of stargazin and the PDZ1, PDZ3, and PD
172 octadecadienoic acid recognizes the specific amino acid motifs of His75, Ala76, and Lys77 in bovine h
175 risingly, Piv contains none of the conserved amino acid motifs of the lambda Int or Hin/Res families
176 cooperative interactions arise from the YPWM amino-acid motif of Ultrabithorax-located amino-terminal
178 studies led to the identification of a four-amino-acid motif on the m2 receptor (Val385, Thr386, Ile
179 ter-binding PNA sequence embedded within two amino acid motifs: one leads to efficient cell/nuclear e
181 es all contain a SET domain, a conserved 130 amino acid motif originally identified in polycomb- and
183 We demonstrate that a highly conserved 8-amino acid motif (P3) located in the linker between tran
184 sity, and, of note, all clones contained the amino acid motif PGGN (or minor variations) in the CDR3
186 a cellular phosphoprotein, CtBP, through a 5-amino acid motif, PLDLS, conserved among the E1A protein
187 (NLS-c), which consists of a bipartite basic amino acid motif plus the last 39 residues of ADAR1.
188 , ESXR1 contains 12 repeats of a unique nine amino acid motif, PPMAP(V/L)PPG, located C-terminal to t
189 be NMR resonances to the specific repetitive amino acid motifs prevalent in spider silk proteins.
190 additional amino acids downstream of the 12-amino acid motif provide necessary structural or conform
193 f 12 predicted transmembrane segments and an amino acid motif, R-X-G-R-R, present at equivalent posit
194 dsRNA do so by utilizing an approximately 70 amino acid motif referred to as the dsRNA-binding domain
195 data from mollusks, mammals and insects, and amino acid motifs reported to be associated with cleavag
196 on of mutant Eps15 protein, which lacks a 14-amino acid motif representing the AP-1 binding site of E
197 edicted polymerase domain containing the GDD amino acid motif required for viral RNA synthesis, was s
199 vian strains of HEV contain a conserved PXXP amino acid motif, resembling either Src homology 3 (SH3)
200 t direct its subcellular trafficking, but an amino acid motif responsible for the targeting of the tr
202 on of Cys102, found in the other radical SAM amino acid motif, resulted in the loss of C-7 methylatio
203 We discovered that Saps 4-6 each contains amino acid motifs RGD/KGD to bind integrins on epithelia
204 primers were designed based on two conserved amino acid motifs, RITGLD, and DI/(F)Y/(F)PNGG, in the t
207 d Saccharomyces cerevisiae contain the three amino acid motif RX( downward arrow)(F/L/I)XX(T/S/G)XXXX
209 to its activity, we identify a conserved 30-amino-acid motif, separable from Dsh-binding regions, th
210 ners are recognised through a conserved four amino acid motif, (serine-X-isoleucine-proline) which ex
213 ce analysis revealed that SphK2 contains a 9-amino acid motif similar to that present in BH3-only pro
219 e showed that a majority of NDN-encoded CDR3 amino acid motifs start at CDR3 position four, well with
220 d trafficking; however, the presence of a 12-amino acid motif starting at this Tyr residue was suffic
221 d reading frame of DSP2, suggesting that the amino acid motif STMIT may contact insulin and contribut
223 encodes a protein with four copies of the WD amino acid motif, suggesting involvement in protein-prot
224 ted with their lack of a conserved CDR1alpha amino acid motif, suggesting that fine specificity for a
225 Nanomolar affinity for PI(3)P by these short amino acid motifs suggests that a newly identified mecha
226 tethered to DNA, tandem repeats of an eight amino acid motif taken from this region stimulate the tr
227 to have significant identity with 72- and 75-amino-acid motifs tandemly repeated in the 190-kDa surfa
230 of these genes encode proteins with an LPXTG amino acid motif that covalently links many virulence fa
231 e identified and used to construct a 130-180 amino acid motif that delimits the bilin lyase domain, a
232 trate that ASP5 cleaves a highly constrained amino acid motif that has similarity to the PEXEL-motif
235 nkyrin consists of 24 tandem repeats of a 33-amino acid motif that is present on a wide variety of ot
237 erminal region we previously identified a 14 amino acid motif that is required for the up-regulation
240 cturally highly conserved negatively charged amino acid motif that is strictly required for Mg(2+) ca
244 a and -1beta, we have identified a conserved amino acid motif that serves as a docking site for host
245 lon was dependent on the integrity of a five-amino acid motif that was identical to the recognition s
247 and lacks any nonsynonymous substitutions in amino acid motifs that are well conserved among retrovir
249 from basal spider lineages reveal mosaics of amino acid motifs that differ radically from previously
250 The cytoplasmic domain of megalin contains amino acid motifs that have the potential to bind to oth
252 tact CAAX (C, cysteine; A, aliphatic; X, any amino acid) motif that is also known to mediate membrane
255 ins contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif (RDM)) tha
259 gnalling proteins PatS and HetN use the same amino acid motif to regulate different stages of heteroc
260 e Francisella FTT0831c/FTL_0325 gene encodes amino acid motifs to suggest it is a lipoprotein and tha
261 s with altered CAAX (where A is an aliphatic amino acid) motifs to direct alternate or no prenylation
262 he vacuolar H(+)ATPase has a C-terminal DTAL amino acid motif typical of PDZ-binding proteins that as
263 ubunit (NFH) tail is composed of a repeating amino acid motif, usually X-lysine-serine-proline-Y-lysi
264 on of this activity identifies a conserved 9-amino acid motif ((V/A)P(I/L)AXXE(S/D)D) required for an
265 been shown to bind to a highly conserved six-amino acid motif very close to the C terminus of adenovi
272 fine the properties of this approximately 20-amino acid motif, we designed a GPR consensus peptide an
276 M-CLL-derived peptides exhibited better amino acid motifs, were more similar to each other, alig
278 cterized by tandem arrays of a degenerate 35-amino-acid motif which form an alpha-solenoid structure.
281 ne acetyltransferase complex through a novel amino acid motif, which is functionally conserved in E2F
283 nt of associated proteins containing an ETGE amino acid motif, which matches the KEAP1 interaction mo
284 a analyses, we demonstrate selection of CDR3 amino acid motifs, which strongly suggests Ag-driven oli
286 This point mutation resides within an eight-amino acid motif with homology to sequences important fo
287 alysis of this domain reveals a composite 10-amino acid motif with interdigitating residues that regu
289 athy profile as well as transporter-specific amino acid motifs with a variety of bacterial and mammal
291 Here we describe an evolutionarily conserved amino acid motif within APLF that is required for mediat
294 eletion of domain VI or of a conserved eight amino acid motif within VI causes loss of all UNC-6 guid
297 ces by targeting sites that encode conserved amino acid motifs within the major capsid protein, VP1.
298 ur analyses revealed a strictly conserved 14-amino-acid motif within the predicted alpha-helical link
300 shares with all sequenced mammalian DSPs an amino acid motif, XILPXLXL, located approximately 80 ami