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1 transporter, and alsT, encoding a predicted amino acid transporter.
2 is imported by T cells via their ASC neutral amino acid transporter.
3 vator" mechanism in the mammalian excitatory amino acid transporters.
4 riminate them from the termini of organellar amino acid transporters.
5 odel for the structure of the SLC1 family of amino acid transporters.
6 into structural features of human excitatory amino acid transporters.
7 ported by cationic (CAT) and y(+)L (y(+)LAT) amino acid transporters.
8 changer, glutamate transporters, and neutral amino acid transporters.
9 as the cell adhesion receptors integrins and amino acid transporters.
10 has been shown to function as a chaperone of amino acid transporters.
11 nalling pathways known to regulate placental amino acid transporters.
12 , which are positive regulators of placental amino acid transporters.
13 ral l-amino acids are substrates of system L amino acid transporters.
14 hen compared with related mammalian cationic amino acid transporters.
15 f K(ATP) channels and activation of system-A amino acid transporters.
16 transferrin receptor and CD98 a subunit of L-amino acid transporters.
17 e solute carrier 36 family of proton-coupled amino acid transporters.
18 signalling and decreased the activity of key amino acid transporters.
19 lysosomal membrane protein with homology to amino acid transporters.
21 nine metabolism, either by blocking cationic amino acid transporter 1 (CAT-1)-dependent arginine upta
22 strocytic glutamate transport via excitatory amino acid transporter 1 (Eaat1), and blocking Eaat1 ext
23 expression of mRNA and protein of excitatory amino acid transporter 1 (GLAST), which is a major compo
24 e glutamate-aspartate transporter/excitatory amino acid transporter 1 (GLAST/EAAT1) in EAE cerebellum
25 ovascular-selective biomarkers large neutral amino acid transporter 1 (LAT-1), glucose transporter ty
28 ilarly, pharmacological inhibition of l-type amino acid transporter 1 (LAT1) and GCN2 significantly i
33 nsated by increased levels of sodium neutral amino acid transporter 1 (SNAT1 or SLC38A1) and SNAT2 (S
34 Expression of the sodium-coupled neutral amino acid transporter 1 (SNAT1), which transports gluta
35 amino groups that bind to the large neutral amino acid transporter 1 (which is expressed in most tum
36 ons in the helical hairpin HP2 of excitatory amino acid transporter 1 form intersubunit disulfide cro
37 permeability-glycoprotein, and large neutral amino acid transporter 1 were significantly higher for 1
38 ate transporters, genderblind and excitatory amino acid transporter 1, in blood cells affects the fli
39 icola The transporter, A. pisum nonessential amino acid transporter 1, or ApNEAAT1 (gene: ACYPI008971
40 transport protein, sodium-dependent neutral amino acid transporter 1, sodium-dependent glutamate/asp
41 uaporins and amino acid transporters (L-type amino acid transporter 1, sodium-independent amino acid
44 ecotropic envelope receptor murine cationic amino acid transporter-1 (mCAT1) in the virus-producing
45 ammation and tumor sites upregulate cationic amino acid transporter 2 (Cat2), coordinately with Arg1
47 sion of the glutamate transporter excitatory amino acid transporter 2 (EAAT2) in LPS-treated astrocyt
50 caused a significant reduction in excitatory amino acid transporter 2 (EAAT2) protein levels in astro
52 lutamate transporters, especially excitatory amino acid transporter 2 (EAAT2, rodent analog GLT1) to
53 icle analysis of purified human 4F2hc/L-type amino acid transporter 2 (LAT2) heterodimers overexpress
55 nts from the cellular sodium-coupled neutral amino acid transporter 2 (SNAT2) versus the hepatitis C
57 porter 2, increased expression of excitatory amino acid transporter 2 repressor ying yang 1, and redu
59 ne, SNAT2 (system A sodium-dependent neutral amino acid transporter 2), contains a C/EBP-ATF site tha
60 e glutamate transporter-1 [GLT-1 (excitatory amino acid transporter 2)] subtype of glutamate transpor
61 gnificantly lowered expression of excitatory amino acid transporter 2, increased expression of excita
62 transporter SLC7A2 (also known as "cationic amino acid transporter 2," or "CAT2") were decreased in
65 xpression of the L-Arg transporter, cationic amino acid transporter 2B, and increased L-Arg uptake in
66 ndent trafficking of the neuronal excitatory amino acid transporter 3 (EAAT3) blocks potentiation, su
68 then taken up by neurons through excitatory amino acid transporter 3 [EAAT3; also termed Slc1a1 (sol
69 otropic glutamate receptor 1, and excitatory amino acid transporter 3) were validated by Western blot
70 SLC36A4, otherwise known as proton-assisted amino-acid transporter 4 (PAT4), in colorectal cancer.
72 glutamate transporter 1), EAAT5 (excitatory amino acid transporter 5), and VAMP2 (vesicle-associated
73 the identification of sodium-coupled neutral amino acid transporter 7 (SNAT7), encoded by the SLC38A7
74 ilability, through endocytosis of sugar- and amino acid transporters (AATs) (Muller et al., 2015).
76 d trophoblast plasma membrane System A and L amino acid transporter activities and transporter isofor
78 ciency inhibits placental mTOR signaling and amino acid transporter activity and causes fetal growth
79 nsporter-mediated histidine uptake, system L amino acid transporter activity and Na(+) K(+) -ATPase a
80 usly to transiently adapt placental System-A amino acid transporter activity relative to fetal growth
81 orter-mediated histidine uptake and system L amino acid transporter activity were similar in sarcolem
82 h wound closure, L-arginine uptake, cationic amino acid transporter activity, and activation of the m
86 a 31-kilobase segment at rhg1-b, encoding an amino acid transporter, an alpha-SNAP protein, and a WI1
88 b region of DNA demonstrate expression of an amino acid transporter and an alpha soluble NSF attachme
89 ected, partially colocalizing with vesicular amino acid transporter and GABA(A)-receptor gamma2 subun
90 anges, we tested the hypothesis that ex vivo amino acid transporter and Na(+) K(+) -ATPase activity i
91 rogram through the up-regulation of selected amino acid transporters and aminoacyl-tRNA synthetases.
93 a translational repressor of mRNAs encoding amino acid transporters and has been postulated to limit
94 eptor (TCR)-induced asymmetric expression of amino acid transporters and RagC-mediated translocation
95 of Myc is to control expression of multiple amino acid transporters and that loss of a single Myc-co
96 milarity of SemiSWEETs and SWEETs to PQ-loop amino acid transporters and to mitochondrial pyruvate ca
98 how that TCR signaling induces expression of amino acid transporters, and renders amino acid-induced
102 cterized protein with sequence similarity to amino acid transporters, as a lysosomal transmembrane pr
103 f how substrate specificity is determined in amino acid transporters, as well as provide novel scaffo
104 ession of Glut1 (glucose) and ASCT2 (neutral amino acids) transporters, as well as that of PiT1 and P
107 apo-ApcT, a proton-coupled broad-specificity amino acid transporter, at 2.35 angstrom resolution.
108 a19 gene as an example, encoding the neutral amino acid transporter B(0)AT1, we studied regulation of
109 inked membrane subunits: the carrier, b(0,+) amino acid transporter (b(0,+)AT), a polytopic protein,
110 amino acid transporter 1, sodium-independent amino acid transporter, B( degrees (,+))-type amino acid
111 ase after bath application of the excitatory amino acid transporter blocker DL-threo-beta-benzyloxyas
112 ssion of pathway inhibitors, upregulates key amino acid transporters, blocks translation initiation,
113 functional ammonium transporters and several amino acid transporters but found no evidence of a nitra
115 o antigen by upregulating expression of many amino-acid transporters, but a single System L ('leucine
116 mTORC1 and mTORC2 regulate human trophoblast amino acid transporters by modulating the cell surface a
117 n complex 1 (mTORC1) and 2 (mTORC2) regulate amino acid transporters by post-translational mechanisms
118 In this study we establish that N-termini of amino acid transporters can also determine substrate spe
119 nslation of the mRNA for the arginine/lysine amino acid transporter Cat-1 increases during amino acid
123 in a region containing two genes: a cationic amino acid transporter (CAT4) and a polynucleotide phosp
124 n assigned to the SLC7 subfamily of cationic amino acid transporters (CATs) due to sequence homology,
125 y 7 member 5 (SLC7A5) gene, which encodes an amino acid transporter cause microcephaly and seizures,
127 eurosecretion-it encodes a putative cationic amino acid transporter, closely related to the Slimfast
128 that differentially localised intracellular amino-acid transporters contribute to the activation of
129 such as induction of potassium channels and amino acid transporters, derepression of genes marked wi
131 in Xenopus laevis oocytes, two bacteriocyte amino acid transporters displayed significant levels of
132 Astrocytic glutamate transporter excitatory amino acid transporter (EAAT) 1, also known as glutamate
133 n is terminated by members of the excitatory amino acid transporter (EAAT) family of proteins that re
135 , we show that application of the excitatory amino acid transporter (EAAT) substrate d-aspartate stim
138 taxia (EA6) have mutations of the excitatory amino acid transporter EAAT1 (also known as GLAST), but
140 reduced the expression of type 2 excitatory amino-acid transporter (EAAT2) and the astrocyte-specifi
141 , it stimulates endocytosis of an excitatory amino acid transporter, EAAT3, in dopamine neurons.
143 II spectrin binds directly to the excitatory amino acid transporter (EAAT4), the glutamate receptor d
144 (SLC1A), which also includes the excitatory amino acid transporters (EAATs) and the prokaryotic aspa
153 mammalian central nervous system, excitatory amino acid transporters (EAATs) are responsible for the
155 ic transmission and activation of excitatory amino acid transporters (EAATs) for transmitter removal.
157 +)/Ca(2+) exchanger (NCX) and the excitatory amino acid transporters (EAATs) in Glu uptake and recycl
159 led a deeper understanding of how excitatory amino acid transporters (EAATs) mediate chloride permeat
165 transporters, also referred to as excitatory amino acid transporters (EAATs), are membrane proteins t
166 ve synapses is carried out by the excitatory amino acid transporters (EAATs), involving the cotranspo
169 glutamate transporters known as "excitatory amino acid transporters (EAATs)." Here we cloned and fun
172 the human glutamate transporters (excitatory amino acid transporters, EAATs) and the prokaryotic aspa
173 pendent glutamate cotransporters (excitatory amino acid transporters; EAATs) exist exclusively in abl
174 ers and that loss of a single Myc-controlled amino acid transporter effectively phenocopies the impac
175 hough no structure of a human proton-coupled amino acid transporter exists, the crystal structure of
176 mour-autonomous Yorkie-mediated SLC36-family amino acid transporter expression as a proline-scavengin
179 Secondary transporters in the excitatory amino acid transporter family terminate glutamatergic sy
182 sodium gradient necessary for system A and N amino acid transporter function, was significantly reduc
183 n proximal tubular cells, mRNA levels of the amino acid transporter gene SLC38A2 were diminished and
194 products of which heterodimerize to form an amino acid transporter in HT-29 cells after bacterial in
197 ies suggest that the increased expression of amino acid transporters in islets can serve as early dia
199 trates a role for reduced Slc6a15, a neutral amino acid transporter, in nucleus accumbens (NAc) in de
200 ed in ATF4-dependent upregulation of several amino acid transporters, including SLC1A5 and its trunca
201 in ceramide, VPA decreased the expression of amino acid transporters, increased the expression of ER
202 ORC1, indicating that the high expression of amino acid transporters induces amino acid-driven mTORC1
203 and activity of the System A/SNAT2 (SLC38A2) amino acid transporter is up-regulated by amino acid sta
204 esearch demonstrates that Slc6a15, a neutral amino acid transporter, is associated with depression su
205 otein expression of SNAT1, 2 and 4 (System A amino acid transporter isoforms) and LAT1 and LAT2, but
206 ) and LAT1 and LAT2, but not CD98, (System L amino acid transporter isoforms) was down-regulated by f
207 h that of BATs, and as LeuT is a promiscuous amino acid transporter, it does not recapitulate the pha
208 2a (5HT2a), and the solute carrier 7-family amino acid transporter, JhI-21, as required for this pre
210 ght to investigate the role of the essential amino acid transporter L-type amino acid transporter (LA
211 d decreased the expression of aquaporins and amino acid transporters (L-type amino acid transporter 1
212 o assess skeletal muscle anabolic signaling, amino acid transporters [large neutral and small neutral
213 the essential amino acid transporter L-type amino acid transporter (LAT) 1 (SLC7A5) in psoriasis.
214 o acid transporter (SNAT), and large neutral amino acid transporter (LAT) isoforms in syncytiotrophob
216 sine derivative rapidly transported by the l-amino acid transporter (LAT-1), with a faster blood pool
219 ransporters [large neutral and small neutral amino acid transporters (LAT1, SNAT2) and CD98], and myo
222 -[(18)F]15 but not (S)-[(18)F]14 by system L amino acid transporters led to approximately 8-10-fold h
223 he past decade, the structure of a bacterial amino acid transporter, leucine transporter (LeuT), has
224 zed sodium-coupled symporters: the bacterial amino acid transporter LeuT, which is the prototype for
226 ed an NFAT-dependent reduction in excitatory amino acid transporter levels, indicating a possible mec
227 er transporter 7a5 (SLC7A5), a large neutral amino acid transporter localized at the blood brain barr
230 rokaryotic NSS homolog, the multihydrophobic amino acid transporter (MhsT) from Bacillus halodurans,
232 rystal structure of ApcT, a proton-dependent amino acid transporter of the APC superfamily, a homolog
236 onjugate (LPS) to interact with ATB(0,+), an amino acid transporter overexpressed in hepatocarcinoma
237 Unexpectedly, members of the proton-assisted amino-acid transporter (PAT or SLC36) family emerged fro
239 osine is a known substrate of proton-coupled amino acid transporters (PATs), which are overexpressed
241 coding a Petunia hybrida plastidial cationic amino-acid transporter (PhpCAT) functioning in plastidia
242 t an interaction with the lysosomal cationic amino acid transporter PQLC2 mediates C9orf72 complex re
243 d-based radiotracers predominantly visualize amino acid transporter processes, and in many cases they
244 nit and the presynaptic vesicular inhibitory amino acid transporter protein showed similar expression
246 c protein, and the helper, related to b(0,+) amino acid transporter (rBAT), a type II glycoprotein.
249 the membrane carrier protein SCAMP3 and the amino acid transporters SLC1A5 and LAT1, directing them
250 placental expression of glucose and system A amino acid transporters Slc2a1 and Slc38a2, respectively
252 ncluding transferrin receptor protein 1, the amino acid transporters SLC3A2 and SLC1A5, and the T-cel
253 leukin 4-dependent induction of the cationic amino acid transporter SLC7A2 (also known as "cationic a
255 regulates transcription of genes that encode amino acid transporters (SLC7A5 and SLC3A2) to promote b
256 dentified a differentially methylated CpG in amino acid transporter SLC7A8 that is highly reproducibl
257 no acid uptake by reducing the levels of the amino acid transporter Slimfast caused clones of PTEN mu
258 Here we report the characterization of the amino-acid transporter Slimfast (Slif) from the yellow-f
259 protein expression of sodium-coupled neutral amino acid transporter (SNAT) 2 was elevated 9-fold.
261 transporter (TAUT), sodium-dependent neutral amino acid transporter (SNAT), and large neutral amino a
262 l accessory proteins Vpu or Nef included the amino acid transporter SNAT1 and the serine carriers SER
263 Impairment of 80S complex assembly on the amino acid transporter SNAT2 IRES was rescued by purifie
269 (18)F-fluoro-phenylalanine ((18)F-FDOPA), an amino acid transporter substrate, as an independent mark
270 selective inhibitors of the human excitatory amino acid transporter subtype 1 (EAAT1) and its rodent
271 all compound library at the three excitatory amino acid transporter subtypes 1-3 (EAAT1-3) resulted i
272 pharmacological properties at the excitatory amino acid transporter subtypes EAAT1, EAAT2, and EAAT3.
273 e smaller placentas with reduced activity of amino acid transporter systems A and L, thought to contr
274 hypothesis that facilitated diffusion by the amino acid transporters TAT1, LAT3 and LAT4 plays an imp
275 analysed two mutants of AAP1 (At1g58360), an amino acid transporter that was localized to Arabidopsis
276 ndidate binding lipoproteins associated with amino acid transporters that may function in indirect se
277 which also includes the mammalian excitatory amino acid transporters that take up the neurotransmitte
278 llular glutamate were mediated by excitatory amino-acid transporters, the reverse dialysis of ammonia
279 ining with gephyrin and vesicular inhibitory amino acid transporter to label GABAergic postsynaptic d
280 ginine-deprived T cells upregulated system L amino acid transporters to increase uptake of essential
283 , and they direct downregulation of distinct amino acid transporters triggered by specific stimuli.
284 ioid receptors, morphine inhibits excitatory amino acid transporter type 3-mediated cysteine uptake v
286 trong expression of the vesicular inhibitory amino acid transporter (VIAAT) mRNA, suggesting a GABAer
287 nohistochemical assessment of LAT1/LAT2/CD98 amino acid transporters was performed in seizure-affecte
288 across plasma membranes occurs via the large amino acid transporter, which is overexpressed in malign
289 regions in neuropil, and express excitatory amino acid transporters, which are presumably required f
290 roliferating tumor cells upregulate specific amino acid transporters, which hold great potential for
291 fetal growth by down-regulation of placental amino acid transporters, which limits fetal nutrient ava
292 operon, urea transport genes (urtBCDE), and amino acid transporters while significant decreases in t
293 at d3 revealed co-localization of the L-type amino acid transporter with GFAP-positive astrocytes but
295 day 3 revealed colocalization of the l-type amino acid transporter, with glial fibrillary acidic pro
296 hat it acts as a sodium-independent cationic amino acid transporter, with unique selectivity to L-his
297 te endosomes and lysosomes is facilitated by amino-acid transporters within the solute-linked carrier
298 beta1, alphaVbeta3, and alphaVbeta5, and the amino acid transporter x-CT protein and enters via c-Cbl
299 general and specialized members of the yeast amino acid transporter (YAT) family, a branch of the ami