ライフサイエンスコーパス: amino group

1 diminishing the leaving group ability of the amino group.

2 uitin carboxy terminus and a substrate lysyl amino group.

3 (II) coordinated by His33 and the N-terminal amino group.

4 abstraction of the proton from the exocyclic amino group.

5 nd histamine without affecting the 1 degrees amino group.

6 tive silylation at the C-H bond gamma to the amino group.

7 the pocket, and they all lack the anchoring amino group.

8 (I) and copper (II) coordinating with thiol/amino group.

9 idue Gly1 becomes trimethylated on the alpha-amino group.

10 reaction between a sulfonyl fluoride and an amino group.

11 tation, and stereoelectronic Umpolung of the amino group.

12 of the hydrogen bond involving the exocyclic amino group.

13 ia electrochemical oxidation of its terminal amino-group.

14 related well with their increasing number of amino groups.

15 -poly(ethylene glycol) (DAPEG) with terminal amino groups.

16 g and 4-ring MDA was determined to be on the amino groups.

17 substrates containing primary and secondary amino groups.

18 the rather different reactivities of the two amino groups.

19 imethylate all the N-terminal and side chain amino groups.

20 almost entirely by the presence of purine 2-amino groups.

21 mocysteine (HCys) belonging to the thiol and amino groups, 2,3-naphthalenedicarboxaldehyde (NDA) can

22 prepare a drug-linker incorporating a basic amino group adjacent to the maleimide, positioned to pro

23 d for some HEW, the regeneration of the free amino groups after loss was observed as a function of ti

24 erlayer vertical hydrogen bonding between an amino group and a carboxylic acid group.

25 intramolecular hydrogen bonding between the amino group and coordinated chlorine molecules.

26 calization of the first cation to the single amino group and destabilization of the second protonatio

27 ong the CHN hydrogen bond, which produces an amino group and initiates polymerization to form a dimer

28 es not require any in situ protection of the amino group and proceeds with 100 % atom-economy.

29 This utilizes the amino group and side chain of the N-terminal His residue

30 is behaviour seem to be related to the alpha-amino group and the other functional groups (mainly amin

31 l Asp reduces the basicity of the N-terminal amino group and, as hence, its charge, by approximately

32 e ion pairs between lysine side-chain NH3(+) amino groups and DNA phosphate groups at the molecular i

33 For the reaction between protein amino groups and DOPAL, a highly toxic metabolite of dop

34 PQ) capable of inducing deamination of Lys e-amino groups and formation of the carbonylated product a

35 BPEI has multiple amino groups and more positive charges in PBS buffer, th

36 rtho- or para-positions of phenolic hydroxyl/amino groups and the C2-position of the indole ring.

37 served, whereas the distance between the two amino groups and the hydrophobic aryl alkyne moiety can

38 s into the pores through coordination to the amino groups, and the resulting MOF is an efficient phot

39 somers can vary depending on the position of amino groups, and the resulting protonation sites play a

40 In particular, amino groups are dynamic components of nucleic acids tha

41 e protected with the 2-cyanoethyl group, and amino groups are protected with acyl groups.

42 First, the alpha-hydroxyl and amino groups are protected with simple protecting groups

43 oselectively without affecting the 1 degrees amino groups (aromatic and aliphatic) of 5-aminoindole,

44 phines functionalized with a remote tertiary amino group as a ligand, readily available acetylenic am

45 of a readily removable nosyl (Ns) protected amino group as the directing group is a crucial practica

46 tic amino substitution and lateral aliphatic amino groups as electron donors.

47 rbamoyl moieties (R7) were appended on the 7-amino group, as well as a para-methoxy group inserted on

48 tor groups at C-2 (CN, SO(2)R) and a primary amino group at C-7 for conjugation via reductive aminati

49 gases require a mechanism to deprotonate the amino group at physiological pH to produce an effective

50 isubstituted derivatives bearing a methyl or amino group at position 2, were prepared, and the biolog

51 Protein can be preconjugated via an amino group at the 3' end of a synthetic DNA molecule, s

52 on can be greatly enhanced by employing a 3'-amino group at the 3'-end of each oligonucleotide, in co

53 In particular, a free amino group at the 5 position with an ethoxycarbonyl gro

54 Introducing an amino group at the C(3) position of the cholate componen

55 However, an amino group at the meta position results in a PPG with b

56 ivileged biphenyl-2-ylphosphine with a basic amino group at the rarely explored 3' position, the deri

57 alkenyl, aryl, alkynyl, fluoro, hydroxyl and amino groups at the beta position of the parent acid, th

58 tions of the D-amino acid side chain and the amino group based on chemical restraints.

59 ere were marked differences in the levels of amino groups between all heated WPI solutions when measu

60 s, with low signal intensities observed from amino groups but none from biological tissue.

61 d that the PRNTase domain recognizes the C-2-amino group, but not the C-6-oxo group, N-1-hydrogen, or

62 ted chrysenes bearing four aryl, alkynyl, or amino groups by means of the Suzuki, Sonogashira, or Buc

63 emonstrate that the measurement of available amino groups by the OPA method is less impacted than by

64 acid (lacking an asymmetric center or alpha-amino group) by using modified ribosomes and pyrrolysyl-

65 Herein, we demonstrate that an ortho amino group can also facilitate benzylic C-O bond cleava

66 rated to provide target compounds displaying amino groups, carboxy groups, hydroxy groups, or triazol

67 r and tethering glyphosate via its secondary amino group, concentrations in aqueous solutions down to

68 bread and the significant reduction of free amino groups confirm the presence of interactions betwee

69 ugar amino acids in the presence of a second amino group connected to the carbohydrate core, share st

70 the quantitative metabolite profiling of an amino group containing drug (levothyroxine) and its meta

71 ibrils was confirmed by determining the free amino group content and the presence of final products f

72 The measurable free amino group content of soy proteins changed from 0.77 to

73 The highest alpha-amino group content was observed in gelatin extracted at

74 Based on free amino groups content measurement, it was found that lact

75 ms in the wild-type protein, suggesting that amino group coordination is absent in the two-nitrogen c

76 Amino group coordination was probed through the creation

77 nwhile, purine nucleosides with an exocyclic amino group could be obtained easily by simple reduction

78 asurement of the rotation rate of individual amino groups could give insight into the dynamic process

79 The amount of free amino groups decreased, with an increase in rate of loss

80 a reduction in the number of available free amino groups, decreased tryptophan intrinsic fluorescenc

81 o monitor the changes in the content of free amino groups during postharvest wheat and flour maturati

82 ween reducing sugars and compounds with free amino groups during thermal processing of foods.

83 In particular, the lysine side-chain amino groups exhibited only small changes in the order p

84 his purpose, dimethylation of the N-terminal amino group followed by dimethylation of lysines was use

85 e acceptor ubiquitin and positions its alpha-amino group for nucleophilic attack on the E3 approximat

86 d by computational assessment of alternative amino groups for the thiocarbamate functionality.

87 omega-TA transferred the amino group from alanine to ketone substrates and finall

88 BCAT2 catalyses the transfer of the amino group from branched-chain amino acids to alpha-ket

89 that catalyze the reversible addition of an amino group from glutamate to pyruvate, yielding alanine

90 DNA variants, respectively, remove or add an amino group from the DNA minor groove, with correspondin

91 ss spectrometry analysis by blocking peptide amino groups from isotopic/isobaric labeling and changin

92 The final amino-group-functionalized, linker-equipped antigen was

93 luble fractions had higher (P </= 0.05) free amino groups, GABA content, antioxidant and angiotensin

94 By modifying amino-groups, glycation interferes with folding of prote

95 aphene oxide (GO) and GO functionalized with amino groups (GONH2) on 15 immune cell populations, inte

96 Strongly basic amino groups had low oral absorption in vivo.

97 the Thr-gamma positions, the pKA of the Thr1 amino group has been measured to be 6.3 and hence deprot

98 new inhibitors and modulating the p K(a) of amino groups, have been employed.

99 in the linker of (2R,7R)-2 or at the primary amino group in 17 resulted in high affinity Y4R radiolig

100 mono- and dimethylate, respectively, the N6 amino group in 23S rRNA nucleotide A2058.

101 ing based on electrochemical oxidation of an amino group in acidic media.

102 Cyclitols having an amino group in an alpha configuration at a position equi

103 tion from the Tyr phenol ring and N-terminal amino group in combination with hydrogen-atom transfer f

104 The presence of the free amino group in enamines could be further used for synthe

105 nal alanine could be methylated on its alpha-amino group in human cells, with trimethylation being th

106 However, owing to the basicity of the -amino group in lysine, this strategy generates a number

107 ond DKA branch of bifunctional DKAs, and the amino group in position 7 of quinolinone ring combined w

108 etween Glu-142 O(epsilon2) and the substrate amino group in positioning the substrate with the correc

109 were overcome by Teoc protection of the beta-amino group in the assembly of 3 and Boc-MOM protection

110 sugar acetyltransferases that modify the C-4 amino group in the bacillosamine or perosamine biosynthe

111 [(3)H]Propionylation of one amino group in the linker of (2R,7R)-2 or at the primary

112 orms an intra-residue hydrogen bond with the amino group in the N4 position.

113 s substituted with an equatorial hydroxyl or amino group in the newly formed ring are considerably mo

114 bly of 3 and Boc-MOM protection of the alpha-amino group in the synthesis of 2, enabling the efficien

115 ort for the importance of the exocyclic N(2)-amino group in this reaction was provided by an experime

116 he alphaAsn249, alphaAsn258, and alphaLys352 amino groups in alpha-tubulin, which supported the forma

117 quantify the rotational dynamics of guanine amino groups in G-quadruplex nucleic acids.

118 In this novel biosensor matrix, amino groups in HKCN were used for the enzyme immobiliza

119 nges attributable to the involvement of free amino groups in Maillard-type reactions were inhibited b

120 eals a distinct approach to install aromatic amino groups in metabolites and raises questions about t

121 es four major steps: (i) acetylation of free amino groups in paCOS using a deuterated reagent; (ii) l

122 surface of the graphite were cross-linked to amino groups in the enzyme so as to attach glucose oxida

123 We have reacted accessible amino groups in the enzyme with bifunctional cross-linki

124 Initially, the importance of secondary amino groups in the polyamine chain was studied by the s

125 It is well-established that secondary amino groups in the polyamine moiety of these toxins are

126 no-1,2,4-oxadiazole, which has nitramino and amino groups in the same building block.

127 oxidized due to the presence of phenolic and amino groups in their structures.

128 The content of free amino groups increased during postharvest wheat and flou

129 Acetylation of lysine -amino groups influences many cellular processes and has

130 ydroxyl group in the natural substrate by an amino group is a promising strategy for inhibition becau

131 lic acid, or amine when an electron-donating amino group is at the meta position, as demonstrated in

132 An amino group is converted into its propynamide and, in aq

133 trategy (a net reductive process in which an amino group is installed at a site remote from the origi

134 Therefore, a free amino group is not required for uphill transport as prev

135 However, if the C4 amino group is replaced with a hydroxy group (to give TD

136 The reactivity of DOPAL with N(alpha) -amino groups is greater than with lysine N(e) -amines an

137 lenediamine derivatives, in which one of the amino groups is part of an urea functional group, has be

138 water-dispersible, few-layer h-BN containing amino groups is presented.

139 Its replacement by an amino group led to decreased activity.

140 ore and replacement or substitution of the 2-amino group led to loss of antimalarial activity.

141 and 14.5 kDa; however, the reduction of free amino group levels and the increase in chromatogram area

142 into proximity for the radical-mediated 1,2-amino group migration.

143 , the introduction of additional hydroxy and amino groups mostly cancelled the inhibitory effect, whi

144 The amino group must carry two substituents, either two aryl

145 st, the unmethylated cytosine's exocyclic N4 amino group (NH2) and its ring carbon C5 atom hydrogen b

146 erization of aniline increases the number of amino groups (-NH2) for antibody immobilization.

147 th a cage surface bearing positively charged amino groups (-NH3(+)) and directly compare it with a si

148 ile transfer of primary (-NH2) and secondary amino groups (-NHR) to heteroaryl- as well as arylcuprat

149 capacities between 0.44 and 1.01 accessible amino groups/nm(2) membrane are achieved.

150 e of imidazole ring and the terminal epsilon-amino group occupying a position nearly identical to the

151 rotected (S)-valine was first coupled to the amino group of (S)-m-triisopropylsilyloxyphenylalanine t

152 C6 of tryptophan is positioned next to the e-amino group of a conserved lysine, confirming the hypoth

153 l-CoA synthetases by acetylating the epsilon-amino group of a conserved, catalytic lysine residue.

154 k of the peptidyl-tRNA by the reactive alpha-amino group of a D-amino acid.

155 ized, of which NatA will acetylate the alpha-amino group of a number of nonmethionine amino-terminal

156 This mixed anhydride is attacked by the -amino group of a specific lysine present on a highly con

157 tide purine, hydrogen replaces the exocyclic amino group of A.

158 DNA can form a covalent adduct with the N(6)-amino group of adenine residues on the opposing strand.

159 DFT calculations revealed that the tertiary amino group of AM reacts with the phenol compounds under

160 se (bGNAT) superfamily acetylate the epsilon amino group of an active site lysine, inactivating Acs.

161 tudy that the proteasome can use the epsilon-amino group of an N-terminal lysine residue in transpept

162 ween the acidic CO(2) molecule and the basic amino group of aniline renders enhanced CO(2) separation

163 upling the carboxyl group of 3b and the free amino group of arylated diazeniumdiolated piperazine 4.

164 f FNP undergoes nucleophilic substitution by amino group of biomolecule and results in its covalent i

165 intrinsic interactions between the cationic amino group of chitosan and iodide ions.

166 residue was connected to the exocyclic N(6)-amino group of dA.

167 ribose adduct attached to the exocyclic N(2)-amino group of dG.

168 threonine is amide-linked to the side chain amino group of diaminopimelic acid within the peptidogly

169 mutant and a specific surface lysine epsilon-amino group of ErbB2, leading to near quantitative cross

170 endent isopeptide bond formation between the amino group of free glutamate and the gamma-carboxyl gro

171 arly shows the crucial role of the exocyclic amino group of G in sequence-specific recognition.

172 ed that carbamate functionalization of the 4-amino group of gemcitabine significantly reduced (>23-fo

173 involved in the initial deprotonation of the amino group of glycine, enabling nucleophilic attack of

174 tivation, can react with the exocyclic N (2) amino group of guanine to generate four stereoisomeric B

175 er of a methyl group from SAM to the epsilon-amino group of histone H3K36.

176 f pyridoxal phosphate, transfers the primary amino group of l-Glu to C-4'' of UDP-4-keto-6-deoxy-d-Gl

177 Here, we show that ALD1 transfers the alpha-amino group of l-Lys to acceptor oxoacids.

178 Acetylation of the epsilon-amino group of Lys-40 of alpha-tubulin marks stable micr

179 tonated donor, which is probably the epsilon-amino group of Lys-96 or a water molecule in its vicinit

180 n that reversible acetylation of the epsilon-amino group of lysine provides an additional means of mo

181 linked to target proteins at the varepsilon-amino group of lysine residues.

182 e general bases that deprotonate the epsilon-amino group of lysine substrate, also involving two near

183 but also other acyl groups from the epsilon-amino group of lysines in histones and other substrate p

184 o determine the pKa for the N-terminal alpha-amino group of methionine1 of ubiquitin for the first ti

185 ranslational modification in which the alpha amino group of mono-l-glutamine is covalently linked to

186 -terminal domain histidine residue and the 2-amino group of OG base are critical for MutY detection o

187 airing of A with OG uniquely positions the 2-amino group of OG in the major groove and provides a mea

188 was covalently coupled to the alpha/epsilon-amino group of one of the seven Lys residues of lycosin-

189 s (AGEs), formed through the reactions of an amino group of proteins with reducing sugars, have been

190 s well with the nucleophilic attack on the 2-amino group of pyridines/pyrazines/pyridazines on the 2-

191 l modification of both Lys-773 and the alpha-amino group of Ser-764.

192 e keto group of the alpha-keto acid, and the amino group of the amino acid.

193 ive addition of an acetyl group to the alpha-amino group of the amino-terminal amino acid of proteins

194 sm whereby E27 specifically recognizes the 2-amino group of the bound substrate and toggles the relea

195 that the l-conformation and protonated alpha-amino group of the first residue were critical for N-deg

196 ilic aliphatic chain attached on the epsilon-amino group of the lysine mycobactin core, which is tran

197 ion of the Ap aldehyde residue with the N(2)-amino group of the opposing guanine residue in 5'-CAp se

198 th 1 and 2 to ascertain the influence of the amino group of this FLP-catalyzed transformation.

199 s provides strong evidence that the terminal amino group of Thr1 serves as the base in the first step

200 dition with the pKa-perturbed Lys-15 epsilon-amino group of TTR.

201 an acetyl moiety from acetyl-CoA to the C-4 amino group of UDP-d-viosamine.

202 hat the PhF group can be introduced into the amino group of Weinreb's amides and methyl esters of ami

203 carboxy terminus of ubiquitin to the epsilon-amino group of, in most cases, a lysine of the substrate

204 of methyltransferases, those that act on the amino groups of adenine or cytosine in DNA, have conserv

205 nd to -SO3H-modified alumina via the primary amino groups of both GS moieties.

206 -isothiocyanate (FITC) was conjugated to the amino groups of bovine serum albumin (BSA).

207 PEF caused a decrease in available free amino groups of BSA in presence and absence of MGO, sugg

208 he pattern of acetylation suggested that the amino groups of chitosan and the polar residues Glu-16 a

209 It reacts with exocyclic amino groups of DNA nucleobases and forms adducts/lesion

210 i of proteins/peptides and at the side chain amino groups of lysine and arginine residues.

211 Ubc9 catalyzes the conjugation of SUMOs to -amino groups of lysine residues in target proteins.

212 the attachment of a polyubiquitin chain to -amino groups of lysine residues.

213 orophore was selectively transferred between amino groups of lysines that reside within ~10 A at the

214 e1 is capable of arginylating not only alpha-amino groups of N-terminal residues but also gamma-carbo

215 results in the amide bond formation between amino groups of PANI and COOH groups of anti-Cab.

216 ic reactions between reducing sugars and the amino groups of proteins and accumulate during aging, di

217 In contrast, the pKa of N-terminal alpha-amino groups of proteins can vary significantly, with re

218 e-mediated catabolism of thiocyanate to free amino groups of proteins.

219 ormed by reactions of MGO with the thiol and amino groups of proteins.

220 X-ray crystallography indicates that the amino groups of some compounds occupy a water-filled poc

221 crosslinking with glutaraldehyde (GA) on the amino groups of the 3D-Au-PAMAM-p-ABA-SPCE, where tau pr

222 e moieties were prepared by derivatizing the amino groups of the dendrimer with 4-carboxy-benzenesulf

223 Pluronic P85 attached randomly to the lysine amino groups of the hormone.

224 dergo posttranslational acylation on epsilon-amino groups of two internal conserved lysine residues b

225 The content of free amino groups of wheat flour was analysed immediately aft

226 cross-links via reaction with the exocyclic amino group on a nearby 2-deoxyguanosine or 2-deoxyadeno

227 Amino group on anti-EpCAM antibody was covalently bound

228 is revealed that Scabin labels the exocyclic amino group on guanine bases in either single-stranded o

229 complexes containing base analogs that the 2-amino group on guanine is the primary molecular determin

230 Due to the presence of a primary amino group on its side chain, lysine is particularly pr

231 s at low energy, which produces high-density amino group on the SiNx surface within a short duration

232 t nucleophilic attack by the substrate alpha-amino group on the sn-2 ester to form a cyclic tetrahedr

233 The presence of a suitably protected p-amino group on the styrene moiety could be exploited, af

234 tegy to selectively prepare stable OACs from amino groups on native proteins is presented.

235 report herein the successful introduction of amino groups onto robustly folded beta-peptoid helices b

236 play a reactive functionality (either a free amino group or carboxylic acid moiety) for further bioco

237 ologs having the chirality center nearby the amino group or the aromatic ring.

238 With a higher number of amino groups per silane molecule increased loading capac

239 ifferent aminosilanes with one, two or three amino groups per silane molecule, namely 3-aminopropyltr

240 Alkylation of the 4-amino group preferentially improves the activity against

241 ssess the increased content of unsubstituted amino groups present in thermally stressed and autoclave

242 nitro groups to amines; in theory, the only amino groups present will have originally been nitro gro

243 ar arrangement by acetylating the N-terminal amino group prior to electrochemical oxidation and cleav

244 Whereas the amino groups proved to be critical to its inhibitory act

245 he highest pKa values ever reported for this amino group, providing a rational for the observed need

246 conditions, SOF4 reliably seeks out primary amino groups [R-NH2 ] and becomes permanently anchored v

247 Initially, amino groups react with reducing carbohydrates, yielding

248 H was determined based on the amount of free amino groups released.

249 nd hydrogen-bond interactions in restraining amino-group rotation.

250 h systems lowers the basicity of the pushing amino-group(s) and increases the basicity of the pulling

251 itrogen bases containing one or more pushing amino-group(s) directly linked to a pulling cyano, imino

252 tential indicate that reactions involving an amino group should occur more easily for the 3-amino- th

253 d record uptakes and rapid capture, with the amino group shown to be vital in improving performance.

254 being more effective in the case of multiple amino groups, since retention is stabilized through inte

255 a covalent postsynthetic modification at the amino group sites within the MOF.

256 xemplified with the functionalization of the amino group, stereospecific oxidation to beta-amino alco

257 roups, which through hydrogen bonding to the amino group successfully overrode steric effects and dir

258 yzing the covalent modification of aliphatic amino groups, such as the lysine (Lys) side chain, by nu

259 O with a diazonium salt bearing a protonated amino group that can further immobilize gold nanoparticl

260 the functionality at the surface; revealing amino groups that are utilized to bind biomolecules in t

261 ized with multiple paired alpha-carboxyl and amino groups that bind to the large neutral amino acid t

262 Lysine contains two amino groups that theoretically may both participate in

263 Among the four protecting groups of the o-amino group, the o-nitro protecting group is the only ch

264 With increasing number of amino groups, the compounds tend to form hydrogen bonds,

265 While acetylation can occur on N(alpha)-amino groups, this review will focus on N(epsilon)-acety

266 poration in melanoidins and are inhibited by amino groups through Maillard reaction.

267 es of ubiquitin, or via its N-terminal alpha-amino group to build linear ubiquitin chains.

268 lite via a carboxylic acid, a hydroxy, or an amino group to form acyl-, O-, and/or N-glucuronide meta

269 ation reagent, which oxidizes the N-terminal amino group to provide a uniquely reactive aldehyde or k

270 he trifluralin structure contains a tertiary amino group, two nitro-groups and a trifluoromethyl- gro

271 ium(II)-aryl complex and a weak base, lysine amino groups underwent C-N bond formation at room temper

272 selective acylation of the l-ornithine alpha-amino group using activated succinimidyl esters.

273 ily, which does not contain the highly basic amino group usually present in other sigma1R ligands, sh

274 ondensation (SVAC), (ii) installation of the amino group via aza-Michael addition/elimination, and cr

275 Introduction of the 2-amino groups via the corresponding azides and introducti

276 n iodocinnabarinic acid diester in which the amino group was masked with two Boc substituents, a Cu(I

277 erence was observed depending on whether the amino group was substituted by a phenyl or an alkyl (usu

278 synthesized by CcTAM revealed that the alpha-amino group was transferred to Cbeta of the phenylpropan

279 ng ester, bromo, chloromethyl, and protected amino groups was developed for the preparation of 5-trif

280 A significant increase in free amino groups was observed in TBs with a dose-response ef

281 h different amino acids containing secondary amino groups was tested under simulated in-vitro conditi

282 d arginines, bearing spacers with a terminal amino group, were incorporated into the peptides by stan

283 depends to some extent on the nature of the amino group, whereas the reactivity has been shown to be

284 tively introduced by phenolic groups than by amino groups which have been much more commonly used so

285 and 50, rather than modifying the N-terminal amino group, which is instead alphaN-acetylated in cells

286 Such oligomers carry free amino groups, which are positively charged at neutral pH

287 reduce the negative inductive effect of the amino group while simultaneously activating the carboxyl

288 ith aryl groups in the alpha-position to the amino group, while (2-methylcyclopropyl)ethanone gives a

289 BS was limited, with slight changes in free amino groups, while GABA, total phenolic compounds and a

290 ter reagent (SPAER), and those peptides with amino groups will be selectively and covalently captured

291 This was demonstrated by replacing the amino group with a more basic guanidine one while mainta

292 ion C4 of the benzene ring to substitute the amino group with an hydroxyl group.

293 ltryptophan occurs at Calpha rather than the amino group with NosL Y90A and replacing the substrate a

294 by selectively labeling the N-terminal alpha-amino groups with a fluorescent reagent followed by enzy

295 actions of these products or the reaction of amino groups with other reactive substances (e.g. alpha-

296 y the Coulomb interactions of their terminal amino groups with the water-exposed negatively charged c

297 o, one, two (cis and trans), three, and four amino groups, with the remaining para substituents carbo

298 through isopeptide bonds at a lysine epsilon-amino group within a specific amino acid sequence.

299 le reaction between aldoses (or ketoses) and amino groups yielding relatively stable Amadori (or Heyn

300 um ion stabilized by the electron-donating 4-amino group yields the final cross-linked product with h