ライフサイエンスコーパス: aminohippurate

1 ial measures of GFR (iothalamate) and RPF (p-aminohippurate).

2 RPF was measured by clearance of para-aminohippurate.

3 t not of estradiol 17beta-d-glucuronide or p-aminohippurate.

4 ohippurate (18F-PFH) is similar to that of p-aminohippurate, a gold standard for the measurement of e

5 hylammonium), decynium-22, carnitine, PHA (p-aminohippurate), alanine, or inosine.

6 Para-aminohippurate, also known as p-aminohippuric acid (PAH)

7 OAT1 inhibitor) and partially reversed by p-aminohippurate (an OAT1 substrate).

8 nd 69 age-matched healthy subjects with para-aminohippurate and inulin clearances and their response

9 h pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mer

10 In addition, p-aminohippurate and the dicarboxylates adipate and glutar

11 Sodium, potassium, lithium, para-aminohippurate, and creatinine clearances were measured

12 retion of the prototypic organic anion, para-aminohippurate, as well as of a large number of commonly

13 sport of the shared OAT1/OAT3 substrate, rho-aminohippurate, behaved similarly, except that stimulati

14 d loss of organic anion transport (e.g. para-aminohippurate) both ex vivo (in isolated renal slices)

15 (inulin), effective renal plasma flow (para-aminohippurate), BP, and hemodynamic responses to an inf

16 Renal plasma flow was measured by para-aminohippurate clearance and was converted to blood flow

17 red pre- and post-CPAP using inulin and para-aminohippurate clearance techniques at baseline and in r

18 Renal plasma flow (para-aminohippurate clearance) and glomerular filtration rate

19 d part of the study, renal plasma flow (para-aminohippurate clearance) and glomerular filtration rate

20 nd renal vascular responses (inulin and para-aminohippurate clearance) to graded doses of an angioten

21 , and renal plasma flow was measured by para-aminohippurate clearance.

22 GFR and RPF were estimated by iohexol and p-aminohippurate clearance; albuminuria was estimated by u

23 cemia (4 to 6 mmol/L): inulin (GFR) and para-aminohippurate (effective renal plasma flow) clearances,

24 Para-aminohippurate extraction was likewise reduced to simila

25 teral GFR, renal plasma flow (RPF), and para-aminohippurate extraction was measured 1 h before and 1

26 for taurocholate, estrone sulfate, and para-aminohippurate in renal slices from wild-type mice, wher

27 restoration of the inhibitory effect of para-aminohippurate (% inhibition 34 +/- 4%).

28 orted probenecid-sensitive uptake of [(3)H]p-aminohippurate (K(m) = 4 microM), which was trans-stimul

29 necid-sensitive and pH-dependent uptake of p-aminohippurate (Km = 15.4 FtM, V,,, ..ax = 20.6 pmol/106

30 , digoxin, and prostaglandin E(2), but not p-aminohippurate or S-dinitrophenyl glutathione.

31 xtracellular alphaKG on the kinetics of para-aminohippurate (PAH) and cidofovir transport was examine

32 Effects of these residues on p-aminohippurate (PAH) and cidofovir transport were assess

33 es the transport of organic anions such as p-aminohippurate (PAH) and estrone sulfate as well as the

34 Para-aminohippurate (PAH) and estrone-3-sulfate transport acr

35 First, 5 mM p-aminohippurate (PAH) cis-inhibited the uptake of 1 micro

36 teral GFR, renal plasma flow (RPF), and para-aminohippurate (PAH) extraction were measured 1 h before

37 he prototypical organic anion substrate para-aminohippurate (PAH) reduced ochratoxin A secretion by a

38 The maximal rate of p-aminohippurate (PAH) secretion, in micromol/min per 100

39 The transporter-mediated p-aminohippurate (PAH) uptake was saturable, probenecid-se

40 rototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocy

41 The uptakes of p-aminohippurate (PAH), estrone sulfate, and ochratoxin A

42 tes was inhibited by sulfate, oxalate, and p-aminohippurate (PAH), indicating affinity for these anio

43 ds and by renal clearance of inulin and para-aminohippurate (PAH), simultaneous cardiorenal hemodynam

44 ened for probenecid-sensitive transport of p-aminohippurate (PAH).

45 well as the prototypical OAT substrate para-aminohippurate (PAH).

46 flow were measured with iothalamate and para-aminohippurate, respectively.

47 Para-aminohippurate significantly inhibited uric acid uptake

48 (tissue/medium (T/M) approximately 8) and p-aminohippurate (T/M = 2) transport.

49 OAT1, and the uptake of model substrate para-aminohippurate was studied in COS-7 cells expressing the

50 The renal clearances of inulin and para-aminohippurate were used to measure GFR and renal plasma