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1 rities and to self-assemble like a molecular amphiphile.
2 ecular self-assembly of a perylene monoimide amphiphile.
3 ntetheinyl transferase to generate a peptide amphiphile.
4 g a biologically inert, low-molecular-weight amphiphile.
5 io-opaque elements encapsulated by synthetic amphiphile.
6 ght of as monodisperse oligomers of a single amphiphile.
7 le by adjusting the structure of the polymer amphiphile.
8 s an effective and well-accessible colloidal amphiphile.
9 formations are prevalent for A blocks of BAB amphiphiles.
10 edia exhibit optical responses to biological amphiphiles.
11 rplays among three components of the T-shape amphiphiles.
12 e identical electronic properties of all PMI amphiphiles.
13 n of nanomaterials based on aromatic peptide amphiphiles.
14 coil" and "globule-rod-coil" protein complex amphiphiles.
15 lar geometry, and hydrocarbon content of the amphiphiles.
16 erting the zwitterions into typical cationic amphiphiles.
17 les from a range of crystallizable polymeric amphiphiles.
18 f-assembled cylindrical micelles of cationic amphiphiles.
19 les from a range of crystallizable polymeric amphiphiles.
20 as a topological isomer pair of these shape amphiphiles.
21 ences from those characteristic of molecular amphiphiles.
22 d regulation of membrane protein function by amphiphiles.
23 bbon in supramolecular assemblies of peptide amphiphiles.
24 nded hydrophilic groups, affording polymeric amphiphiles.
25 oton motive force, similar to other cationic amphiphiles.
26 nanofiber formed by self-assembly of peptide amphiphiles.
27 s consisting of proapoptotic peptide-polymer amphiphiles.
28 self-assembling features of these dendritic amphiphiles.
29 can be preserved by using photocrosslinkable amphiphiles.
30 lity, attributed to the unusual shape of the amphiphile: a relatively rigid molecule composed of a la
32 However, we find that anionic and cationic amphiphiles adopt strikingly different structures at liq
33 ies formed by synthetic alkyl triazole-based amphiphiles against interfaces of thermotropic liquid cr
34 f a new class of cardanol-derived functional amphiphiles, along with their ability to generate hierar
37 molecular vaccines, through the synthesis of amphiphiles (amph-vaccines) comprising an antigen or adj
40 report here on the self-assembly of peptide amphiphiles and fatty acids driven primarily by anion-pi
41 groups increases the cohesion energy of the amphiphiles and favors the formation of two-dimensional,
42 mphiphiles, which thereby demix from neutral amphiphiles and form spots or rafts within vesicles as w
43 es (Sterosomes) formulated with single-chain amphiphiles and high content of sterols have been develo
44 polar and hydrophobic groups, such as ionic amphiphiles and proteins, is of paramount importance in
45 n vivo correlations that emphasize promising amphiphiles and successful formulation optimization effo
46 cation of an elastin-like protein by peptide amphiphiles and with the capacity to access, and be main
47 drimers, polyvalent metals, metal complexes, amphiphiles, and alkaloids allow tailoring properties fo
48 utting of long CNTs in the presence of lipid amphiphiles, and for validation of CNTP incorporation in
49 o constitutionally isomeric aromatic peptide amphiphiles (APAs), K(S)C'EK(S) and C'EK(S)K(S) (K(S) =
50 nditions, these stimuli-responsive molecular amphiphiles are able to assemble into different structur
55 , we report that the same "fragrant" dynamic amphiphiles are ideal to screen for new siRNA transfecti
58 on hybrids, in which perylene diimide (PDI) amphiphiles are noncovalently immobilized onto single wa
61 the aggregates formed in water by head/tail amphiphiles are revisited and discussed from the point o
62 ally well-segregated yet the B blocks of ABA amphiphiles are significantly less stretched than in the
64 ive phase behaviors of these molecular shape amphiphiles are unique and have not been systematically
66 , we report here the use of isomeric peptide amphiphiles as molecular building blocks to create one-d
67 ermolysin-responsive peptide-based polymeric amphiphiles assembled into spherical micellar nanopartic
69 that underpin the field of aromatic peptide amphiphile assembly, paving the way to a more rational d
71 possible to draw firm conclusions regarding amphiphile association in solution from crystallographic
72 paper unmask new nonequilibrium behaviors of amphiphiles at LC interfaces, and provide fresh approach
73 d that collision and subsequent spreading of amphiphiles at the interface generates a surface pressur
74 ar force probes to measure the net effect of amphiphiles, at concentrations often used in biological
76 ated a small library of structurally similar amphiphiles based on poly(2-oxazoline)s and poly(2-oxazi
80 n transmitting the effect of the cooperative amphiphile binding to the i-face as a structural change
81 areful selection of LHGs, different types of amphiphiles (both polymer and small-molecule surfactants
83 govern the self-assembly of aromatic peptide amphiphiles by focusing on four segments, (i) the N-term
85 rooctyl chain attached to a perylene diimide amphiphile can dramatically enhance the strength of supr
87 or explorations into how nonnatural membrane amphiphiles can be used to both study and enhance the pr
88 ssumption that opportunely designed cationic amphiphiles can behave as CD14/MD-2 ligands and therefor
93 s) represent the most recent self-assembling amphiphiles capable of forming monodisperse, stable, and
96 ctivity relationships were drawn within each amphiphile class, presenting the cellular and animal mod
97 To this end, the use of small molecules, amphiphiles, colloids, and polymers have been investigat
99 of pre-existing vesicles upon an increase in amphiphile concentration either through solvent evaporat
101 echanisms that would lead to increased local amphiphile concentrations is an important aspect of defi
103 supramolecular assemblies of a novel peptide amphiphile containing aldehyde functionality in order to
104 viously we showed that liposomes of cationic amphiphiles containing mannose-mimicking shikimoyl headg
105 repared from polymer-peptide block copolymer amphiphiles containing substrates for protein kinase A,
107 conjugates, small molecule prodrugs, or drug amphiphiles) could involuntarily aggregate, or self-asse
108 lves intercalation of the lipid tails of DNA amphiphiles (CpG motifs for TLR-9 stimulation) into the
110 examined enhanced tumor-specific delivery of amphiphile-CpG, an albumin-binding analog of CpG ODN, fo
112 fferent metals in the porphyrin ring for the amphiphiles described here) in variable proportions.
113 d and synthesized a novel class of glucoside amphiphiles, designated tandem malonate-based glucosides
118 nanoporous network, whereas carboxylic acid amphiphiles do not adopt this nanoporous network due to
119 hydrogen-bonded beta-sheets, and chromophore amphiphiles driven to assemble by pi-orbital overlaps--w
120 of bulky, membrane-disruptive supramolecular amphiphiles due to "too strong" binding of anions to tri
121 e study of enzymatic hydrolysis of polymeric amphiphiles due to the monodispersity and symmetry of th
123 by addition of both zwitterionic and neutral amphiphiles (e.g., diheptanoylphosphatidylcholine or Tri
124 sical properties change upon addition of new amphiphiles (e.g., lipids, alcohols, peptides, or protei
127 means of two supramolecular systems--peptide amphiphiles engaged in hydrogen-bonded beta-sheets, and
128 water as the selective solvent, these shape amphiphiles exhibited versatile self-assembled micellar
130 tives of this maltose-neopentyl glycol (MNG) amphiphile family show favorable behavior relative to co
131 e developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from co
137 s knowledge in the design of novel synthetic amphiphiles, formulations, and revolutionary screening a
138 producing a self-assembling aromatic peptide amphiphile from amino acid precursors that temporarily e
140 ylene glycol) (PEG)-pyropheophorbide-a (Ppa) amphiphiles (G320P, G310P, G220P, and G210P) are synthes
143 tocells derived from phospholipids and other amphiphiles have been made and their enzymatic-driven mo
148 id side-chains along the PNA backbone yields amphiphiles having a "protein code" that directs self-as
149 specific interactions between water and the amphiphile head groups, both at the interface and in the
150 imple expedient of mixing slightly different amphiphiles (i.e., different metals in the porphyrin rin
151 eins bind to and interact with the polymeric amphiphiles in both their assembled and monomeric states
152 he development of diagnostics, and learn how amphiphiles in general use lipid trafficking to navigate
153 ecently reported on the activity of cationic amphiphiles in inhibiting TLR4 activation and subsequent
154 measurements were performed on the discotic amphiphiles in mixtures of water and alcohol at temperat
156 nducing properties of the promising cationic amphiphiles in syngeneic C57BL/6J mice under prophylacti
159 dictates the kinetics and structures of the amphiphiles in the organic phase as they decorate the in
160 eparation protocols to self-assemble peptide amphiphiles in water can result in the formation of diff
162 , we synthesize a series of methanofullerene amphiphiles, including derivatives of C60, C70, and C84,
163 s of 1 nM, measured for PEO-rich bottlebrush amphiphiles, indicated an enhanced thermodynamic stabili
165 hat aggregates of decanoic acid, a prebiotic amphiphile, interact with the bases and sugar found in R
167 s, their modified versions, and other single amphiphiles into liposomes, and from block copolymers in
169 stigations on the self-assembly of dendritic amphiphiles into various nanostructures in water on the
172 spontaneous formation of membranes from such amphiphiles is a concentration-dependent process in whic
173 formation of graphene derivatives by natural amphiphiles is essential for elucidating the biological
180 s been drawn between them, organic molecular amphiphiles (MAMs) and inorganic nanoparticle (NP) amphi
181 ness in three-dimensional artificial peptide amphiphile matrices offers a chemical strategy to contro
183 show that the 2D crystallization process in amphiphile membranes can be controlled by modifying the
184 on early Earth and other rocky planets, and amphiphile-mineral interactions in diverse other phenome
185 ows the renormalized bending stiffness of an amphiphile mixture membrane tube in contact with a flat
186 ing cryogenic electron microscopy, a peptide amphiphile molecule containing aromatic residues was fou
187 eveloped a series of self-assembling peptide amphiphile molecules that transform either isolated from
189 embly of two model series of molecular shape amphiphiles, namely, hydrophilic [60]fullerene (AC(60))
190 y to study the molecular exchange of peptide amphiphile nanofibres, supramolecular systems known to h
192 synthetic cell-free therapy based on peptide amphiphile nanostructures designed to mimic the activity
193 hiles (MAMs) and inorganic nanoparticle (NP) amphiphiles (NPAMs) are significantly different in dimen
200 ssembling dilysine (+2) and carboxylate (-1) amphiphiles of various tail lengths into bilayer membran
201 The solution self-assembly of macromolecular amphiphiles offers an efficient, bottom-up strategy for
203 , we designed a series of symmetric triblock amphiphiles (or high-chi block oligomers) comprising inc
205 eport here on a coassembly system of peptide amphiphile (PA) molecules designed to form nanofibers fo
206 ane disruption was integrated into a peptide amphiphile (PA) that self-assembles into bioactive, cyli
208 self-assembly of mixtures of bilayer-forming amphiphiles, particularly phospholipids and micelle-form
209 The predictive powers should extend also to amphiphile partitioning and the kinetics of lipid-monome
212 ramolecular liquid crystal formed by peptide amphiphiles (PAs) that encapsulates cells and growth fac
217 Cell-like hybrids from natural and synthetic amphiphiles provide a platform to engineer functions of
219 alent ligands within a mixture of polyvalent amphiphiles provides, in principle, a simple mechanism f
222 lf-assembly of molecular and block copolymer amphiphiles represents a well-established route to micel
223 expressed by the minimum volume fraction of amphiphile required to form microemulsion (Phi(ME)), whi
224 e on a proof-of-concept bioconjugate polymer amphiphile, revealed growth and evolution occurring by u
225 inding chemistry to design a new fluorinated amphiphile, RfNTA, using an improved one-step synthesis
226 y grafted with macromolecules ('nanoparticle amphiphiles') robustly self-assemble into a variety of a
228 er membranes composed of simple single-chain amphiphiles seem to be well-suited for a potential role
230 he ability of ionic liquids (ILs) to support amphiphile self-assembly into a range of mesophase struc
231 tructures that are formed, and (iii) how can amphiphile self-assembly materials be used to enhance pr
233 In this review we discuss ionic liquids as amphiphile self-assembly media, and identify trends that
234 To reproducibly engineer the low energy amphiphile self-assembly of materials for the future, we
237 ecent key findings regarding (i) what drives amphiphile self-assembly, (ii) what governs the self-ass
241 ructures obtained from natural and synthetic amphiphiles serve as mimics of biological membranes and
242 uman aortic endothelial cells with exogenous amphiphiles, shown previously in model membranes, and co
243 antages of cholesterol with those of charged amphiphiles, stabilizing the aligned phase and preventin
244 his study we systematically examined whether amphiphiles such as indomethacin influence Ras protein n
246 levels and high concentrations of exogenous amphiphiles, suggesting it as a general feature of the o
247 The results reported here show that peptide amphiphile supramolecular systems can be dynamic and tha
249 ithin the same energy landscape, the peptide-amphiphile system forms a thermodynamically favoured pro
250 low as 1.0 using mixed surfactant or polymer-amphiphile systems with significant positive charge/numb
253 rylated once more to generate a farnesyl-CoA amphiphile that self-assembles into spherical micelles.
254 in aqueous media produces a bola-type supra-amphiphile that self-assembles to produce higher order m
256 These results demonstrate that only the amphiphile that thinned Ld lipid domains increased beta1
257 his aggregate consists of three inequivalent amphiphiles that assemble to create 3- and 6-fold rotati
258 are designing novel cationic and procationic amphiphiles that can pack, transport, and deliver nuclei
259 rticles are colloidal analogues of molecular amphiphiles that can self-assemble to form diverse supra
260 work is motivated by one class of molecular amphiphiles that change their surfactant properties in r
261 e have assembled a series of nanosized shape amphiphiles that comprise a triphenylene core and six po
262 ort the crystal structures of several tripod amphiphiles that contain an N-oxide hydrophilic group.
263 s, we prepared a small collection of anionic amphiphiles that could recognize cations by ionpair-pi i
264 d evaluation of a new class of benzothiazole amphiphiles that exhibit a dose-dependent response leadi
265 gating dendritic alkyl chains to DNA creates amphiphiles that exhibit high-affinity (Kd in low nanomo
267 convert nonstructure forming molecules into amphiphiles that spontaneously assemble into vesicles.
269 n the dimension mismatch of the two types of amphiphiles, the entanglement of polymer chains, and the
273 PRAS), nanostructured liquids generated from amphiphiles through sequential self-assembly and coacerv
274 f-assembly and physicochemical properties of amphiphiles, thus affecting their biological effects.
275 ed by rational design in the headgroup of an amphiphile to generate small micelles with enhanced stab
276 The ability to utilize multiple distinct amphiphiles to construct discrete assemblies represents
277 PEG chain induces self-assembly of polymeric amphiphiles to form micrometer-sized vesicles entrapping
279 The presence of zwitterionic and neutral amphiphiles (to which the protein binds weakly) dilutes
284 xtures under the influence of three nonlipid amphiphiles, vitamin E (VE), Triton-X (TX)-100, and benz
286 tizing perylene monomimide (PMI) chromophore amphiphiles were found to show variation in hydrogen gas
287 or spectroscopic investigation is to form an amphiphile, which is able to disperse the latter at the
288 D in toxicity induced by U18666A, a class II amphiphile, which triggers cell death by impairing the t
289 ns are shown here to crossbridge polyanionic amphiphiles, which thereby demix from neutral amphiphile
293 c function of perylene monoimide chromophore amphiphiles with different alkyl linker lengths separati
295 interactions of supramolecular assemblies of amphiphiles with fluid interfaces at the single-event le
296 on (1)H-(13)C HSQC experiments, complexes of amphiphiles with more than 10 different maltooligosaccha
297 dispersities were obtained from bottlebrush amphiphiles with packing parameters of approximately 0.3
298 functionalized polymer to give rise to shape amphiphiles with precisely defined surface chemistry and
299 versus fibers) in a series of simple peptide amphiphiles with the sequence c16-xyL3K3-CO2H where c16
300 ebiotic synthesis of fatty acids and related amphiphiles would result in dilute solutions well below