ライフサイエンスコーパス: amputee

1 trafascicular stimulation in one transradial amputee.

2 ck be provided to the tetraplegic patient or amputee.

3 under the prosthetic feet of two transtibial amputees.

4 t, phantom sensations in spinal patients and amputees.

5 lished touch input in targeted reinnervation amputees.

6 igit on the normal, contralateral hand in 15 amputees.

7 iority in operation and improved comfort for amputees.

8 of TMR to improve postoperative outcomes in amputees.

9 mobility and quality-of-life for lower limb amputees.

10 through implanted nerve interfaces in seven amputees.

11 t function is a top priority for transradial amputees.

12 g somatosensation may improve locomotion for amputees.

13 e motor intent and evoke sensory precepts in amputees.

14 ime control experiments involving upper-limb amputees.

15 th legs of athletes with BKA compared to non-amputees.

16 ostheses can improve the quality of life for amputees.

17 s relationship to phantom pain in upper limb amputees.

18 e to the development of novel treatments for amputees.

19 e a functional remapping of S1 in lower limb amputees.

20 t towards embodiment of the device for these amputees.

21 areas of the hand in targeted reinnervation amputees.

22 ena observed in human targeted reinnervation amputees.

23 Interfaces are fabricated for 9 limbs from 8 amputees (1 bilateral).

24 Tissue specimens obtained from an amputee 10 weeks after gene therapy showed foci of proli

25 ugh such intrusions are commonly reported in amputees [5, 6].

26 n may be a satisfactory treatment option for amputees, a careful selection of candidates and a rigoro

27 gn of prosthetic arms have helped upper limb amputees achieve greater levels of function.

28 study, we found that toe tapping of all the amputees activated the bilateral hand area, including ca

29 Relative to controls, amputees also showed increased activity within the forme

30 Here, we investigated how each system (i.e. amputee and powered prosthesis) responds to changes in t

31 incipal component analysis to gradually mesh amputee and typical walking patterns.

32 olving the identification of cold objects by amputees and by non-amputee participants, and compared w

33 es between digits in the amputees or between amputees and control subjects.

34 for direct neuroprosthetic applications for amputees and disabled individuals.

35 nd reaction time) on 12 upper and lower limb amputees and found that consistently reported perceiving

36 he residual and intact limbs in trans-tibial amputees and healthy controls.

37 s based on artificial neural networks in two amputees and in four out of six intact-bodied subjects.

38 al normal skin of the targeted reinnervation amputees and on analogous sites in able-bodied controls.

39 applied to restore arm and hand function for amputees and paralysed persons.

40 he primary motor cortex in upper-extremities amputees and to determine if the acquisition of special

41 he contralateral chest and arm skin of these amputees, as well as on the chest and arm skin of a cont

42 advantage of at least 0.13 m compared to non-amputee athletes.

43 ensation to locomotor deficits in below-knee amputees (BKAs) has not been fully explored.

44 al amputee (right lower limb), (3) bilateral amputee (both lower limbs), (4) trilateral amputee (lowe

45 This suggests that in amputees, both hand areas work together more collaborati

46 Previous studies reported that amputees, but not one-handers, show increased ipsilatera

47 Amputees cannot feel what they touch with their artifici

48 Compared with a matched amputee cohort without the afferent augmentation, the ma

49 Similarly, amputees commonly complain of the weight of prosthetic l

50 e active prosthesis were more similar to non-amputees compared to using a passive prosthesis.

51 structural changes in the corpus callosum of amputees, compatible with the hypothesis that phantom se

52 to be similar to normal ranges for both the amputees' contralateral skin and also for the control po

53 Our results suggest transfemoral amputees could benefit from load-adaptive powered knee c

54 s used to map CN in controls and in forelimb amputees during the first 12 weeks following deafferenta

55 -knee amputation expend more energy than non-amputees during walking and exhibit reduced push-off wor

56 ctrically stimulating the residual nerves of amputees elicited somatosensory percepts that were felt

57 such as prosthetic limbs worn by millions of amputees every day, cannot adapt to fluctuations in the

58 red to healthy controls, both tendons in the amputees exhibited increased thickness at the mid- and d

59 Previously we showed that amputees experiencing highly vivid phantom sensations ma

60 nnervated chest skin of three shoulder-level amputees following targeted reinnervation surgery.

61 ures that allow gait-deviation perception in amputee gait and (2) whether there are differences in ob

62 is symmetric and economical; hemiparetic and amputee gait is often asymmetric and requires more energ

63 o areas became significantly stronger in the amputee group.

64 sing basic fMRI analysis, we found that only amputees had more ipsilateral activity when motor demand

65 anced multivariate fMRI analyses showed that amputees had stronger and more typical representation-re

66 a presented, it seems that the bilateral arm amputees have a strong potential to develop new skills i

67 rforming an analogous optimization for a non-amputee human, we predict that an amputee walking with a

68 volume/shape based on the preference of the amputee in real-time, acting as a spatiotemporally adapt

69 nd tested it with two targeted reinnervation amputees in a series of experiments fashioned after the

70 etween active and passive prostheses and non-amputees in coordination of balance throughout gait on r

71 ctile feedback in prostheses greatly assists amputees in doing daily tasks.

72 In a camp for amputees in the capital city Freetown, Medecins Sans Fro

73 ive prosthesis was different compared to non-amputees in trunk contributions to sagittal-plane H duri

74 elevant cutaneous touch feedback may help an amputee incorporate an artificial limb into his or her s

75 Across acquired amputees, individuals' reported motor control over their

76 at tactile stimulation of the intact foot in amputees induced a greater activation of ipsilateral S1,

77 o explore whether this observed remapping in amputees involves recruiting more neural resources to su

78 in postural stability, unilateral lower-limb amputees (LLAs) heavily rely on visual and vestibular in

79 and right upper-limb), and (5) quadrilateral amputee (lower and upper limbs).

80 l amputee (both lower limbs), (4) trilateral amputee (lower-limbs and right upper-limb), and (5) quad

81 After chronic deafferentation in amputees, MEP amplitudes and motor output curves in smal

82 discovery of persistent digit topography of amputees' missing hand could be exploited for the develo

83 We found that key aspects of acquired amputees' missing hand representation persisted, despite

84 preserved, though latent, representation of amputees' missing hand.

85 ntrollers, and controller adjustments affect amputees more when they walk with (versus without) load.

86 einnervation, a novel surgical technique for amputees, offers the potential for returning this lost s

87 in recognition scores between digits in the amputees or between amputees and control subjects.

88 A regression analysis comparing controls and amputees over the first 12 weeks post-amputation found s

89 Demonstrations include intact and amputee participants using the modified prosthesis to pe

90 ation of cold objects by amputees and by non-amputee participants, and compared with traditional bulk

91 ents from 10 able-bodied and two transradial amputee participants.

92 ese data were compared with those of control amputee patients (n = 6) and healthy controls (n = 12).

93 Neuroprosthetics research in amputee patients aims at developing new prostheses that

94 When this reinnervated skin is touched, the amputees perceive that they are being touched on their m

95 , and cognitive load while three transradial amputees performed a modified Clothespin Relocation Task

96 ly influence missing hand signal processing, amputees performed phantom hand movements during anodal

97 Amputees' precision drawing performances with their left

98 their control, thus ultimately improving the amputees' quality of life.

99 e percepts in some neurological patients and amputees; referral of touch to an absent or anaesthetize

100 ired missing hand (hereafter one-handers and amputees, respectively), relative to two-handed controls

101 n eight elderly persons and two transfemoral amputees revealed that stability against falls improved

102 network: (1) 4-limbs control, (2) unilateral amputee (right lower limb), (3) bilateral amputee (both

103 cost--even lower than assuming that the non-amputee's ankle torques are cost-free.

104 ically relevant aspects of a lower extremity amputee's gait, it is currently unknown what the complia

105 more intense, and noxious stimulation of an amputee's phantom limb using transcutaneous nerve stimul

106 ensory expression of the missing limb in the amputee's reinnervated skin.

107 In contrast to some amputee simulations which track experimentally determine

108 S, patient-reported comprehensive lower limb amputee socket survey (CLASS) outcomes to determine the

109 cts (p < 0.001), though this depended on the amputee subject (p < 0.001).

110 aradigm allowed us to simultaneously measure amputee subject and prosthetist subject preferences, and

111 bjects preferred a 26% higher stiffness than amputee subjects (p < 0.001), though this depended on th

112 After each trial, the amputee subjects and prosthetist subjects indicated the

113 were also considerably less consistent than amputee subjects in their preferences (CV of 5.6% for am

114 In the second part of the experiment, amputee subjects were instructed to communicate verbally

115 ubjects in their preferences (CV of 5.6% for amputee subjects, CV of 23% for prosthetist subjects; p

116 able-bodied individuals and one transradial amputee, the two methods were similarly influenced by no

117 In a cohort of seven leg amputees, the interface is shown to augment residual mus

118 come a burgeoning treatment option for adult amputees, there have been no successful cases previously

119 For the two unilateral amputees, these thresholds were similar to measures on t

120 eatment of postamputation pain in major limb amputees, TMR improved PLP and trended toward improved r

121 developed as a neural-machine interface for amputees to address these issues.

122 ectly to the residual nerves of trans-tibial amputees to elicit sensations referred to their missing

123 We suggest that this may help amputees to more effectively incorporate an artificial l

124 f residual limb and stump (nonvolar) skin of amputees to pressure-responsive palmoplantar (volar) ski

125 the interaction between powered prostheses, amputee users, and various environments may allow resear

126 We obtain simulations of an amputee using an ankle-foot prosthesis by simultaneously

127 Bilateral arm amputees usually are excellent foot users.

128 fit evaluation was demonstrated in an adult amputee volunteer who underwent CT evaluation while wear

129 become mechanically coupled when lower limb amputees walk with powered prostheses, but these two con

130 Five transfemoral amputees walked with and without load (i.e. weighted bac

131 oskeleton is a viable solution for improving amputee walking economy.

132 ns which track experimentally determined non-amputee walking kinematics, here, we explicitly model th

133 for a non-amputee human, we predict that an amputee walking with an appropriately optimized robotic

134 emonstrated that the major gait deviation of amputees was the medial-lateral body sway and spatial ga

135 In amputees, we observed an expansion of activation maps of

136 Point localization thresholds for these amputees were found to be lower for their reinnervated s

137 nnervated skin of the targeted reinnervation amputees were found to be similar to normal ranges for b

138 Three transhumeral amputees were implanted with an osseointegrated percutan

139 ctivity when restoring sensory perception to amputees, which could chart a route ahead for designing

140 s restoring sensory perception to upper-limb amputees, which includes the whole spectrum from gentle

141 ion and direct control in eight transhumeral amputees who had TMR in a balanced randomized cross-over

142 lds and point localization thresholds on two amputees who had undergone the targeted reinnervation su

143 a 6-month clinical study with 3 transradial amputees who received implants of transverse intrafascic

144 om the biceps brachii in 5 male transhumeral amputees who underwent targeted reinnervation of this mu

145 Fifteen unilateral trans-tibial amputees who utilized a prosthesis with a PTB feature an

146 Conversely, amputees who wish to replace a lost limb must assimilate

147 Amputees who wish to rid themselves of a phantom limb mu

148 fferentially activate sensorimotor cortex in amputees with and without phantom limb pain.

149 Sciatic nerves from amputees with and without type 2 diabetes (T2D) were exa

150 g task and fMRI to investigate 8 adult human amputees with chronic (mean 33 years) unilateral dominan

151 28 amputees with chronic pain were assigned to standard tre

152 Existing prosthetic limbs do not provide amputees with cutaneous feedback.

153 We investigated 6 bilateral arm amputees with or without special foot movement skill.

154 nal MRI (fMRI) we investigated 13 upper limb amputees with phantom limb pain (PLP) during hand and li

155 e for remapping of both forehead and lips in amputees, with no significant relationship to the chroni

156 asping movements by a paralytic person or an amputee would greatly facilitate her/his activities of d