ライフサイエンスコーパス: analogue

1 ulin (HTI-286), a similarly potent synthetic analogue.

2 rporated into a dimer, compared to a monomer analogue.

3 properties relative to the original O-based analogue.

4 the highest reported for a fluorescent base analogue.

5 ducts as compared to the bulk alpha-MoC(1-x) analogue.

6 le in the conformational preferences of each analogue.

7 cks within the marsh, an artificial mangrove analogue.

8 rties to the previously reported Ir(2)In(8)S analogue.

9 photolysis with UV light of the U(IV) azide analogue.

10 em distinct from their corresponding Group 4 analogues.

11 CL efficiency than the corresponding 2-nitro analogues.

12 s into a more stable series of benzylic core analogues.

13 ol solvent 10x faster than their hydrophilic analogues.

14 gradation profile compared with their linear analogues.

15 ers with much higher branching than 1-alkene analogues.

16 8-based analogues were superior to C20-based analogues.

17 -C-disubstituted BCPs including various drug analogues.

18 he bromo substituent in beta,gamma-CHBr-dNTP analogues.

19 ce and rats challenged with fentanyl and its analogues.

20 rotein, without the use of special dipeptide analogues.

21 late-stage functionalization of several drug analogues.

22 shorter halogen bonds than non-hydrogen bond analogues.

23 by 2-8 orders of magnitude compared to other analogues.

24 s binding mode impedes the hunt for superior analogues.

25 ulosis (tbNadE) with synthetase intermediate analogues.

26 of W=O alkyl complexes from their W carbyne analogues.

27 ower factors than those of the Bi-containing analogues.

28 al activity relative to previously described analogues.

29 e first doubly base-stabilized B(3) H(4) (+) analogues.

30 t the ability to bind to human-like receptor analogues.

31 e accessible redox states than the monomeric analogues.

32 r is 500 times greater than that of unlocked analogues.

33 tively, which was converted to 2-aminomethyl analogue 1 via sulfinamide 2.

34 affinity/selectivity, e.g., C2-phenylethynyl analogue 15 (MRS7591, K(i) = 10.9/17.8 nM, at human/mous

35 e to identify a novel agonist, the synthetic analogue 2-fluoro-ATP, and to confirm its agonist activi

36 The quinone analogue 2-heptyl-4-hydroxyquinoline-N-oxide inhibited C

37 energy levels than those of their pentacene analogues (2.23 and 2.01 eV redox, respectively), simila

38 A BCP analogue (22) was found to be equipotent to its parent p

39 lene, 2, and its N,N-bridged cyclophane-like analogue, 3.

40 Using the spaceflight analogue 30 days of strict 6 degrees head-down tilt bed

41 al fluorescent emitters and that with linear analogue (6.9%).

42 The most potent analogue, 8-[(1H-benzotriazol-1-yl)amino]octanoic acid (

43 The (6-OH)Tic-containing analogue 9 also exhibited high NTS2 affinity (K(i) = 1.7

44 , methamphetamine, heroin, fentanyl, and its analogues), adulterants, and diluents based on density,

45 llow further optimization of lead epothilone analogues aiming to improve their potencies and other ph

46 most cases more active than the homogeneous analogue, allow easy purification of products from the c

47 in the presence of the non-hydrolysable ATP analogue AMP-PNP at an overall resolution of 3.1 angstro

48 he complex formed by an improved teixobactin-analogue and Lipid II and reveal how teixobactins recogn

49 the selective binding between a macrocyclic analogue and the alpha9alpha10 nicotinic acetylcholine r

50 achieve therapeutically important 2-pyridone analogues and arylated acid synthons.

51 rd hydroxyanthraquinones and S-alkylated SAM analogues and catalyzes efficient installation of reacti

52 a(40) aggregation, we investigated eight (8) analogues and evaluated their amyloid-prevention capabil

53 ladine D (2), and a series of stereochemical analogues and explore their antimicrobial activity for t

54 transformation used to deliver higher-value analogues and has important utility in the chemical indu

55 demonstrate that some conjugates act as dNTP analogues and HIV-1 reverse transcriptase (RT) catalytic

56 undescribed class of carbocyclic nucleoside analogues and provided a proof of concept for applicatio

57 ssible by imine-linked frameworks, amorphous analogues, and 1D conjugated polymers.

58 tinal chromophore of gR by synthetic retinal analogues, and have concluded that the CD bands originat

59 ed in hypersusceptibility to DCS, an alanine analogue antibiotic that inhibits alanine racemase and d

60 trically substituted squaramide and its thio analogue are consistent with the syn-syn conformation be

61 n this group is cyclosporin A, several other analogues are available, including some enantiomeric and

62 ols to furnish enantioenriched dysideanone's analogues are performed by employing density functional

63 e dumping syndrome symptoms and somatostatin analogues are preferred for patients who do not respond

64 , the total syntheses of malacidin A and its analogues are reported by a combination of Fmoc-based so

65 Azide-modified inositol (InoAz) analogues are valuable as inhibitors and have shown prom

66 in coronaviruses and define this nucleotide analogue as a direct-acting antiviral.

67 selectivity indices for select 2'-conjugated analogues as compared to MTM.

68 ate continued development of synthetic InoAz analogues as inhibitors or MCRs of inositol-containing g

69 -2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues as potent HAdV inhibitors.

70 e report a series of alpha-aminobenzylphenol analogues as potent PDI inhibitors.

71 les heel for SARS-CoV, supporting nucleoside analogues as promising candidates for the treatment of C

72 collection of compounds revealed kojic acid analogues as TEAD inhibitors, which covalently target th

73 10-phenanthroline and some of its methylated analogues as templates.

74 f nabilone, a synthetic tetrahydrocannabinol analogue, as a treatment for non-motor symptoms (NMS) in

75 everal key advantages over their crystalline analogues, as they provide isotropic structural colorati

76 sistent insights into how paroxetine and its analogues bind to the central substrate-binding site of

77 A BODIPY-labeled analogue binds proteins including PDIA1, suggesting that

78 elative to BPA and one petroleum-derived BPA analogue (bisphenol F, BPF), and the incorporation of mo

79 Treatment with the cAMP analogue Br-cAMP to mimic cAMP rise at maturation onset

80 , in contrast to Laurdan and its carboxylate analogue C-Laurdan.

81 y include topical corticosteroids, vitamin D analogues, calcineurin inhibitors, and keratolytics.

82 al characterization of a new oligonucleotide analogue called thiophosphoramidate morpholinos (TMOs).

83 gical evaluation studies showed that several analogues can impair the growth of C. trachomatis withou

84 Digit Modalities Test, or its computer-based analogues, can be used to monitor episodes of acute dise

85 2-butene-1,4-dial (BDA) and its chlorinated analogue, chloro-2-butene-1,4-dial (Cl-BDA), after the c

86 mation temperature for the Ca(12)Ga(14)O(33) analogue compared to Ca(12)Al(14)O(33) synthesized using

87 l evaluation of truncated spirastrellolide A analogues comprised of the southern hemisphere against p

88 on of a new class of nucleoside triphosphate analogues comprising a C-alkyl-phosphonate moiety replac

89 Azateixobactin analogues containing other stereoisomers of aza-threonin

90 rmation of carbocation 6 and its substituted analogues correlates with the C-H arylation outcomes.

91 a capuramycin phenoxypiperidinylbenzylamide analogue (CPPB) inhibits DPAGT1 enzyme with an IC(50) va

92 These findings suggest that some "non-analogue" crustacean communities co-existed with the "Ma

93 The clinical success of thalidomide analogues demonstrates the therapeutic efficacy of drug-

94 assays performed with water-soluble quinone analogues, demonstrating the importance of testing compo

95 number of exceptionally potent epothilone B analogues, demonstrating the potency enhancing effects o

96 for rat P2X2 receptors; triphosphate-bearing analogues display broad activity, tolerating a number of

97 titutions, and diphosphate and monophosphate analogues display very little activity.

98 n vitro MutY excision rates with different A analogue duplexes do not correlate with the impact on ov

99 mising results for the more challenging beta-analogues (ee's up to 80%).

100 TS analogue enzyme inhibitors are specific for their target

101 l evaluation of a series of new epothilone B analogues equipped with novel structural motifs, includi

102 ular dichroism relative to a smaller helical analogue, even though they share a similar structure: bo

103 the methyl-substituted analogue, the phenyl analogue exhibits a dual emission (cyan and red) that ca

104 could not be isolated, the heavier BP-doped analogue exhibits remarkable solution and solid-state st

105 Analogue experiments on phyllosilicates formed under low

106 quinone-2,6-disulfonate (AQDS, a widely used analogue for quinone- and hydroquinone-containing molecu

107 The approach delivers multiple analogues from a single lead at nanomole-scale amounts a

108 hemoenzymatic approach to synthesize terpene analogues from diphosphorylated precursors produced in q

109 While several ATP analogues gave responses of similar magnitude to ATP, in

110 Compared with their protein analogues, GRAP is highly programmable and exhibits redu

111 One of these analogues has excellent activity against several strepto

112 toexcited dihydronicotinamides like NADH and analogues have been found to generate alkyl radicals upo

113 ld of modern electronics, their monolayer 2D analogues have shown great promise for next-generation e

114 s the study of many-body states that have no analogue in other fields of physics(3).

115 Immunological evaluations of these analogues in BALB/c mice indicate that truncating the C2

116 was detected among individual prostaglandin analogues in patients on monotherapy.

117 of light-induced isomerization of azobenzene analogues in these host-guest systems.

118 ms, as well as two N-substituted ixabepilone analogues in which the 12,13-epoxide and macrolactam NH

119 Nucleoside 5'-triphosphate (dNTP) analogues in which the beta,gamma-oxygen is mimicked by

120 lysis of propenylbenzenes (eugenol and seven analogues) in the essential oils, a broadly distributed

121 Further modifications derived analogues, including 7e, 7f, 7g, and 9k, that addressed

122 The properties of analogues, including solubility, stability, and toxicity

123 We report achiral AR-42 analogues incorporating a cycloalkyl group linked via a

124 1) compared to the same stretch in the CF(3) analogue, indicating a significantly stronger HB interac

125 trations, and molecular assays revealed that analogues inhibit the transcriptional activity of EWS-FL

126 ment of an orally efficacious ribonucleoside analogue inhibitor of influenza viruses, MK-4482/EIDD-28

127 This is among the first of the TS analogue inhibitors of methyltransferase enzymes to show

128 The metabolic conversion of nucleoside analogues into their triphosphates often proceeds insuff

129 An optimized Cbz-PEG(6) analogue is presented that is stable in blood (t(0.5) ~

130 mple, the OH stretch of an amino-substituted analogue is red-shifted by roughly 50 cm(-1) compared to

131 napses at the 10 nm scale, a scalable neuron analogue is yet to be found.

132 the activity of teixobactin and teixobactin analogues is observed with the inclusion of 0.002% of th

133 umes of a library of 80 adenosine nucleotide analogues is rapid and straightforward.

134 The antiviral efficacy of many nucleoside analogues is strongly dependent on their intracellular a

135 Application of JH analogue (JHA) in the 1-day-old adults, significantly ac

136 The 18-crown-6 (18-c-6) Tb(II) analogue, [K(18-c-6)(2)][Tb(NR(2))(3)], 3-Tb, also react

137 Minigastrin (MG) analogues, known for their high potential to target chol

138 structure was shown to be dispensible, with analogues lacking key pharmacophoric residues in one dim

139 ' = I, Me, (t)Bu, Ph, and p-NCC(6)H(4)); the analogues m-{-C(O)-C(5)H(3)N-(C(O)PMe)}(2) and m-{-C(O)-

140 moiety gave rise to an equipotent benzamide analogue M4K2149 with reduced off-target affinity for th

141 s revealed that the 5-amino-1,3,4-oxadiazole analogues may have limited brain permeability.

142 Analogue-memory-based neuromorphic computing can be orde

143 ted in direct comparison to its carbonaceous analogues Mes-[10]CPP and [10]CPP.

144 ctive form, the triphosphorylated nucleoside analogue metabolites.

145 led analysis of the simulations and a simple analogue model indicate that extreme directional changes

146 esults can inform numerical and experimental analogue models of dyke propagation, and thus facilitate

147 We use analogue models of normal faults to demonstrate that, wi

148 o become polymerase substrates, a nucleotide analogue must be phosphorylated by cellular kinases whic

149 Compared to their N-methyl analogues, N-trifluoromethyl azoles have a higher lipoph

150 negative patients on long-term nucleos(t)ide analogue (NA) therapy; cohort B: 23 antibodies against h

151 20 antagonist, by developing a new and novel analogue, NBD-14189 (Ref1), which showed antiviral activ

152 One of the new analogues, NBD-14270 (8), showed a marked improvement in

153 ayed the permeation of a fluorescent glucose analogue (NBDG) between HeLa cells coupled by Cx26 gap j

154 patients or therapy-induced by nucleos(t)ide analogues (NUC).

155 The subsequent identification of thymidine analogue nucleoside reverse transcriptase inhibitors as

156 strate its mode of activity as a competitive analogue of acetyl-CoA.

157 The first acceptor-free heavier germanium analogue of an acylium ion, [RGe(O)(NHC)(2)]X (R = (Mes)

158 ron microscopy structure of ALG6 bound to an analogue of dolichylphosphate-glucose at 3.9 angstrom re

159 The carbon analogue of EBS, namely, 2-phenyl-3H-isoindol-1-one, was

160 water-soluble, non-hallucinogenic, non-toxic analogue of ibogaine that can be prepared in a single st

161 key or unexpected notes may elicit a musical analogue of language N400 effects, but only for familiar

162 The orthorhombic phase of GeSe, a structural analogue of layered SnSe (space group: Pnma), has recent

163 An analogue of MACE2 containing 2,6-dimethyl-l-tyrosine (MA

164 oherent spectroscopies that were the optical analogue of multidimensional nuclear magnetic resonance

165 while pic30-3 is also defective in chlorate (analogue of nitrate) transport and also shows reduced up

166 Here we introduce this novel selenium analogue of pheomelanin through chemical and biosyntheti

167 ound Fe(2+) and N-oxalylglycine, which is an analogue of the cosubstrate 2-oxoglutarate.

168 rts resulted in the discovery of M4K2009, an analogue of the previously reported ALK2 inhibitor LDN-2

169 electrostatic gating, there is as of yet no analogue of these effects for emergent magnetic monopole

170 vity, we designed chlorinated and brominated analogues of a known peptoid and its shorter counterpart

171 adicals formed from silicon-containing heavy analogues of alkenes is of great importance for their ap

172 can be readily derivatized into C-glycoside analogues of beta-glycoconjugates, including C-disacchar

173 valuable class of building blocks for novel analogues of bioactive peptides.

174 eration, in flow generation, and crystalline analogues of CF(3)CHN(2) were developed during the past

175 Main group analogues of cyclobutane-1,3-diyls are fascinating due t

176 been applied to the synthesis of fluorinated analogues of diltiazem and tiazesim, both therapeutic ag

177 es and methods provided a series of designed analogues of disorazole B(1), whose biological evaluatio

178 We used synthetic analogues of dolichylphosphate-linked and dolichylpyroph

179 hod of preparing ether, thioether, and amine analogues of galiellalactone was developed.

180 Here, semisynthetic analogues of hit were designed, synthetized, and tested

181 D1 expression to the synthesized phosphonate analogues of homologous 2-oxodicarboxylates.

182 Twenty-six analogues of loratadine were isolated and fully characte

183 introduced to Great Britain may function as analogues of novel anthropogenic habitats for insects an

184 targeted screening revealed these ligands as analogues of perfluorosulfonic acids and homologues of a

185 diamines can be converted into unprecedented analogues of rhodamine and malachite green possessing a

186 vely specialised input and output processes: analogues of scanner and printer interfaces that feed in

187 Through a systematic screening of 39 analogues of SPD-304, a dual inhibitor of tumor necrosis

188 The synthesis of a series of vinylated analogues of sphingosine-1-phosphate together with their

189 Analogues of the conformationally dynamic Claritin (lora

190 uted housanes can be considered as flattened analogues of the corresponding cyclopentane derivatives

191 A series of novel 1,4-dioxane analogues of the muscarinic acetylcholine receptor (mACh

192 velutibol B and a series of N-terminal lipid analogues of the natural products.

193 nd photophysical properties of various novel analogues of the orphan fluorophore class Singapore Gree

194 studies were performed for the first time on analogues of the southern hemisphere.

195 The reaction of O-acetyl analogues of these N,O-acetals with triflic acid in 1,1,

196 hich we refer to as Pillar[6]MaxQ along with analogues P[5]AS and P[7]AS toward guests 1-18.

197 atures led to the identification of a potent analogue, PK150, that showed antibacterial activity agai

198 ncluding those shown to produce pGpp and its analogue (pp)pApp.

199 nd cellular activity confirm that Omomyc and analogues presented here, are potent binders of the E-bo

200 Remdesivir (GS-5734), a nucleoside analogue prodrug, has inhibitory effects on pathogenic a

201 Furthermore, the alpha-ketoacid analogues provide a natural route for the synthesis of a

202 Via reservoir engineering and analogue quantum simulation techniques, current experime

203 Main group carbonyl analogues (R(2) E=O) derived from p-block elements (E=gr

204 The effects of specific PUFA analogues range from selective for a specific ion channe

205 lation of acid-base free main group carbonyl analogues, ranging from a lighter boracarbonyl to the he

206 ominated this field, with main group element analogues receiving far less attention.

207 zed, and evaluated the simplest bryostatin 1 analogues reported to date, in which bryostatin's A- and

208 1T-MoS(2) and single-atom modified analogues represent a highly promising class of low-cost

209 he inaccurate and unpredictable switching of analogue resistive memory.

210 nd cytokine secretion from abacavir/abacavir analogue-responsive CD8(+) T-cell clones was measured us

211 Oxoborane carbamate and carboxylate analogues result from the in situ trapping of [BO(2) ](-

212 Remarkably, all analogues retained the low nanomolar activity of native

213 Biological evaluation of these analogues revealed a number of exceptionally potent epot

214 thermore, the crystal structure of the amino analogue reveals an interesting feature in which an exte

215 , structure-activity analysis of cholesterol analogues reveals that incorporation of C-24 alkyl phyto

216 hen easily converted into N-alkyl and N-acyl analogues (RX, NaHCO(3)/DMF/100 degrees C) in high overa

217 The satisfaction visual analogue scale (VAS) after using the medical device was

218 (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outc

219 ator; the outcome was pain intensity (Visual analogue scale [VAS]) and physical function (Western Ont

220 fort and esthetics were assessed with visual analogue scale after 7 days and 6 months, respectively.

221 Quality of Life-5 Dimensions-5 Level visual analogue scale at 12 weeks.

222 severity rated a median 7 points on a visual analogue scale from 1 to 10.

223 C30 global health status and EQ-5D-5L visual analogue scale scores were observed in post-consolidatio

224 c health status assessed by the EQ-5D visual analogue scale was 65.9 (standard deviation = 20.1) in p

225 We compared pain perception (100 mm visual analogue scale), muscle sympathetic nerve activity (MSNA

226 ays 3, 5, 10, and 14 using a 10-point visual analogue scale.

227 In this Perspective, positional analogue scanning is shown to be an effective strategy f

228 ssments (including the EuroQoL-5D-3L, Visual Analogue Score for pain, and the short form 36 health su

229 using a standardized questionnaire with 0-10 analogue scores and yes/no questions to determine reflux

230 n investigated at the level of compounds and analogue series.

231 ntify preferred substituents on the basis of analogue series.

232 he design, synthesis, and evaluation of such analogues, several of which were found to possess human

233 Several analogues showed inhibition, which is a positive indicat

234 F1 with bedaquiline or novel diarylquinoline analogues showed potentiation without inducing genotoxic

235 LKB1 cleavage but that only the PEG-extended analogues significantly improve physiologically activity

236 A set of insulin analogues site-specifically derivatized with sialic acid

237 nts that perform Boolean operations and find analogue solutions to a computationally hard graph-parti

238 n pattern observed from the T = 3/2 isobaric-analogue state in rubidium-73, which is identical to the

239 Filament-free, bulk-RRAM cells instead store analogue states using the bulk point defect concentratio

240 These insulin analogues still stimulate efficient glucose disposal in

241 Abacavir and ten analogues stimulated CD8(+) T-cell IFN-gamma release.

242 rrelate observed in vitro MutY activity on A analogue substrates with their experimental and calculat

243 channel contribution-flecainide, but not its analogues, suppressed RyR2-mediated Ca release at clinic

244 electrolytes yield deterministic and linear analogue switching for efficient inference and training.

245 This was followed by hit expansion and analogue synthesis to further improve upon these initial

246 Several of the HZ analogues synthesized in this study are highly potent in

247 tandem to create novel oligonucleotide (ON) analogues that are hitherto unexplored in the oligothera

248 Bimodal PNAs are first examples of PNA analogues that can form DNA2:PNA:DNA1 double duplexes vi

249 ic preparation of pocket-modified vancomycin analogues that directly address the underlying mechanism

250 ng new series of (R)-azetidine-2-carboxamide analogues that have sub-micromolar potencies.

251 Molecular docking of analogues that retained antiviral activity demonstrated

252 tructure enabled the synthesis of simplified analogues that retained both potency and selectivity for

253 Analogues that stimulated T-cells displayed a perturbati

254 A analogues that were not excised from duplex DNA as effic

255 Unlike the methyl-substituted analogue, the phenyl analogue exhibits a dual emission (

256 ce and stability in comparison to their lead analogues, their performance improvements have so far la

257 s and activity after long-term nucleos(t)ide analogues therapy still represents a technical challenge

258 l series of fluorine-substituted cyclohexene analogues, thereby identifying 8 and 9 as novel selectiv

259 thyl ethers and phenols into six fluoroalkyl analogues through late-stage functionalization of a natu

260 the core structure of loratadine and related analogues through N-oxidation affects antihistamine acti

261 ties when compared to a library of dipeptide analogues, thus validating the uniqueness of the molecul

262 om linker enables its respective bisubstrate analogue to occupy both substrate- and cofactor-binding

263 class of coiled-coil proteins that serve as analogues to form a laminal structure at the nuclear per

264 ile cellular repair was the ability of the A analogues to H-bond with the Hoogsteen face of OG.

265 id library containing imidazole or imidazole analogues to perform a structure-activity correlation an

266 hed synthesis of five-membered tetramic acid analogues to six-membered cycles.

267 nement, we characterize the binding of eight analogues to the bacterial ribosome at high resolution,

268 rboxylates increased from ~2.0 for C(4)-C(6) analogues to ~92 for perfluorotridecanoate (C(13)).

269 first example of ultrasound-assisted polymer analogues transformation of chitin unaccompanied by noti

270 ters as well as interferon and nucleos(t)ide analogue treatment choice.

271 ome by IFN-gamma and by TDM or its synthetic analogue trehalose-6,6-dibehenate (TDB).

272 nascent RNA sequencing, we show that an AS15 analogue triggers the unfolded protein response in gliob

273 to yield ultimately the bioactive nucleoside analogue triphosphates (NTP).

274 omparative cytotoxicity assays of 41 MTM(ox) analogues using E-twenty-six (ETS) fusion-dependent and

275 e separation and analysis of six cyclosporin analogues using liquid chromatography (LC) and different

276 Here we demonstrate that PUFA analogues vary in their selectivity for human voltage-ga

277 the synthesis of enantiomerically pure InoAz analogues via traditional approaches is challenging.

278 -scale synthesis of the most active selenium analogue was developed using a previously unreported sel

279 volved in the methyl transfer; a bromoethoxy analogue was used to explore the active site topography;

280 he lipid affinity of each of the three novel analogues was weaker than that of gHwTx-IV, but stronger

281 er as the active material to a perdeuterated analogue, we demonstrate the interplay between the zero-

282 the synthesis of paromomycin and/or neomycin analogues, we describe a cleavage of ring I from paromom

283 for flavanols, stilbenes and phenyl ethanol analogues were improved between 65 and 1000% as compared

284 vailability in dogs indicated that C18-based analogues were superior to C20-based analogues.

285 Seventeen abacavir analogues were synthesized and cytokine secretion from a

286 Tenofovir (TFV) analogues were synthesized by conjugating with amino aci

287 A total of eight spirastrellolide A analogues were synthesized, and preliminary PP2A enzyme

288 Three other analogues were synthesized, thus highlighting the utilit

289 Tafluprost, a prostaglandin analogue which lowers the IOP, has shown to also improve

290 -binding sites of NTMT1, but the bisubstrate analogue with a 5-C atom linker only interacts with the

291 A pseudopeptide analogue with high affinity for both HLA-B*08 and the ER

292 Here, we show that analogues with an N-terminal polyethylene glycol (PEG) e

293 Two neurosteroid analogues with diazirine moieties replacing the 3-hydrox

294 ure-activity relationship within a series of analogues with different substituents at the N(3) positi

295 rmed gamma-C-(alkyl)-nucleoside triphosphate analogues with high selectivity because of an enzyme-tri

296 hips (SAR) of colchicine alkaloids and their analogues with modified A, B, and C rings, as well as hy

297 e La antigen protein demonstrate that lactam analogues with muted nonspecific thiol reactivities cons

298 tructure activity relationship and delivered analogues with nanomolar potencies.

299 the predicted binding poses of the abacavir analogues within the HLA-B*57:01 peptide binding groove.

300 eristic of many hundreds of their structural analogues XM(YCH(2)CH(2))(3)N (M = Si, Ge, Sn, Pb, Ti, A