ライフサイエンスコーパス: angiogenic

1 nic and miR-30clo Serpine1hi ECs were highly angiogenic).

2 Rnasel-1 and Rnasel-2 have been shown to be angiogenic.

3 lity of MC(TC)LUVA to alter endothelial cell angiogenic activities in vitro and ex vivo.

4 rowth factor-A expression and enhances their angiogenic activity and reduces cardiomyocytes and endot

5 ibute to tumor progression through their pro-angiogenic activity in addition to immunosuppressive fun

6 inhibited vessel development and suppressed angiogenic activity in transgenic zebrafish models.

7 The low angiogenic activity of CD271+ MSCs and improved early st

8 y study showed increased uptake in AVMs with angiogenic activity, compared with surrounding tissue wi

9 ty, compared with surrounding tissue without angiogenic activity, suggesting that (68)Ga-RGD PET/CT i

10 The anti-angiogenic agent, diamino propane tetraiodothyroacetic a

11 low as 5 muM, rendering it a promising anti-angiogenic agent.

12 he study of polymeric nanoparticles and anti-angiogenic agents and offers new insight for the rationa

13 rs with microsatellite instability, and anti-angiogenic agents may be used in combination with other

14 mechanism of action: VEGF inhibitors or anti-angiogenic agents, EGFR inhibitors, mTOR inhibitors, CTL

15 new insight for the rational design of anti-angiogenic agents.

16 cated with bisphosphonate, denosumab or anti-angiogenic agents.

17 ecrease in HIF-1alpha modulated a couple key angiogenic and anti-angiogenic factors, resulting in an

18 ays and stems from the imbalance between pro-angiogenic and anti-angiogenic factors.

19 ial-specific deletion of Sdc2 display marked angiogenic and arteriogenic defects and impaired VEGFA(1

20 ma-associated herpesvirus (KSHV) is a highly angiogenic and invasive vascular tumor and the most comm

21 tions of the corneal and limbal epithelia in angiogenic and lymphangiogenic privilege, we designed fi

22 Alternatively, they can secrete pro-angiogenic and matrix-remodelling soluble mediators that

23 2 signaling pathway may reprogram the immune angiogenic and microenvironments and enhance effectivene

24 (i.e., miR-30chi Serpine1lo ECs were poorly angiogenic and miR-30clo Serpine1hi ECs were highly angi

25 We showed previously that the angiogenic and neurotrophic cytokine, vascular endotheli

26 and IL12P40, and increased expression of the angiogenic and neurotrophic factors VEGFA and IL7.

27 EAK (TNFSF12) induced several EGR1-dependent angiogenic and osteoclastogenic factors (e.g., PDGFA, TG

28 EGR1 regulates angiogenic and osteoclastogenic factors, informing the u

29 in metastasis that EGR1 expression regulates angiogenic and osteoclastogenic properties of metastases

30 he VEGFR2/AMPK/PEG3 axis integrates the anti-angiogenic and pro-autophagic bioactivities of decorin a

31 ripasudil-treated groups, and mRNA levels of angiogenic and pro-inflammatory factors in ripasudil-tre

32 immune cell infiltration, and mRNA levels of angiogenic and pro-inflammatory factors in the grafted c

33 Silencing of HIAR abrogated the pro-angiogenic and pro-migratory function of hypoxic CAFs by

34 enal cell carcinoma broadly distributed into angiogenic and proliferative/ immunogenic clades.

35 MSCs are naturally pro-angiogenic and proreparative, and thus numerous techniqu

36 suppress the foreign body response, are pro-angiogenic and support recipient-derived de novo blood v

37 hers to replicate the anti-inflammatory, pro-angiogenic and trophic effects of stem cells without the

38 tory responses, tumour-cell shedding and pro-angiogenic and/or growth factors, might facilitate the p

39 f Prox1 promoted the growth of desmoplastic, angiogenic, and immunologically silent tumors through de

40 UL33 activated multiple proliferative, angiogenic, and inflammatory signaling pathways in HEK29

41 Arterial, endothelial, venous, angiogenic, and mural cell markers were significantly up

42 hoinositide recycling provides a useful anti-angiogenic approach.

43 la henselae to identify such factor as a pro-angiogenic autotransporter, called BafA.

44 We will discuss angiogenic biomarker assays for disease-risk stratificat

45 FKBPL may be a useful anti-angiogenic biomarker in CVD in the absence of diabetes a

46 nation as compared to a previously developed angiogenic biomarker(7), the soluble fms-like tyrosine k

47 Importantly, disrupting the orientation of angiogenic blood vessels by misdirecting them results in

48 effects of zoledronic acid, and restored the angiogenic capacity in vitro.

49 The in vitro angiogenic capacity of CNP was examined in pulmonary mic

50 However, the angiogenic capacity of COX-deficient ECs is severely com

51 The angiogenic capacity of endothelial cells was assessed in

52 gated the differentiation, wound healing and angiogenic capacity of plastic adherent MSCs (PA MSCs) v

53 ial cell population, we defined subsets with angiogenic capacity plus clear signs of endothelial to m

54 Insulin Gene Enhancer Protein (ISL2) and its angiogenic capacity were inversely related to survival a

55 onstrates that the 3D-printed hydrogels with angiogenic cells hold great promise for penile reconstru

56 genic peptide ephrinB2/CTF2, the VE-cadherin angiogenic complexes and EC sprouting and tube formation

57 , EphB4 stimulates the VE-cadherin/Rok-alpha angiogenic complexes known to mediate sprouting angiogen

58 his hypothesis, ischemia-induced VE-cadherin angiogenic complexes, levels of neoangiogenesis marker E

59 empted to distinguish these forms from their angiogenic counterparts, experimentally.

60 s to other N-cysteine proteins including the angiogenic cytokine interleukin-32.

61 form networks in Matrigel, but did generate angiogenic cytokines.

62 Bevacizumab, an anti-angiogenic drug, added to standard chemotherapy demonstr

63 Introduction of anti-angiogenic drugs targeting vascular endothelial growth f

64 he tumor growth accompanied by a higher anti-angiogenic effect compared to the free bevacizumab.

65 To test the anti-angiogenic effect of PSP-2, a recently developed high af

66 xenograft tumors and displayed a strong anti-angiogenic effect, suggesting dual cancer fighting prope

67 size, in cytokeratin-7+ cells and by an anti-angiogenic effect.

68 genic factors, resulting in an enhanced anti-angiogenic effect.

69 ntrast, transfection with VEGF RNA triggered angiogenic effects by promoting VEGF protein secretion f

70 Furthermore, NOS3 knockdown abrogated the angiogenic effects of AM.

71 rcted mouse heart explants responsive to the angiogenic effects of HS-binding Vegfa(164) but did not

72 -binding Vegfa(164) but did not modulate the angiogenic effects of non-HS-binding Vegfa(120).

73 n the endothelium, VEGF mediates most of its angiogenic effects through VEGF receptor 2 (VEGFR2).

74 le arrest at the G1-S phase and elicits anti-angiogenic effects.

75 th over time by bioluminescence and the anti-angiogenic effects.

76 The upregulation of several pro-angiogenic ELR+ chemokines and other angiogenic inducers

77 We find that Slug upregulation in angiogenic endothelial cells (EC) regulates an EMT-like

78 implantation quality depends on appropriate angiogenic events driven by the integration of CB2 in en

79 vessel reassembly, but did impair subsequent angiogenic expansion of the reassembled vessels.

80 egulation of visual cycle genes, and altered angiogenic factor expression.

81 Placental growth factor (PlGF) is an angiogenic factor identified in the maternal circulation

82 on of angiopoietin-like 4 (ANGPTL4), a known angiogenic factor in cancer, in tumors from obese mice.

83 ar endothelial growth factor-A (VEGF) is the angiogenic factor promoting the pathological neovascular

84 Slug (but not Snail) is activated by the pro-angiogenic factor SDF1alpha via its canonical receptor C

85 cular endothelial growth factor (VEGF) is an angiogenic factor that play important roles in the nervo

86 evMDSC have increased expression of an anti-angiogenic factor thrombospondin 1 (Tsp-1) and decreased

87 oxic CAFs by decreasing secretion of the pro-angiogenic factor VEGFA and consequently reducing VEGF/V

88 s point to L1-DeltaTM as a novel, EC-derived angiogenic factor which may represent a target for innov

89 ration of placental growth factor (PlGF), an angiogenic factor, integrated with a clinical management

90 Although originally identified as an angiogenic factor, VEGF also signals directly to neurons

91 rs (e.g. CD31) as well as mRNA expression of angiogenic factors (e.g., Vegfa, Flt1, Klf4).

92 dysfunctional with respect to the release of angiogenic factors and functions including thrombosis, a

93 Delivery of pro-angiogenic factors has shown some benefit, but it is dif

94 s prospective cohort studies have shown that angiogenic factors have a high diagnostic accuracy in wo

95 -mutated MDSCs significantly secrete various angiogenic factors in MDSCs regardless of hypoxia or nor

96 Protein and mRNA abundance of several angiogenic factors including CXCL1, VEGF, and IL-8 are d

97 RAB11B-AS1 enhanced the expression of angiogenic factors including VEGFA and ANGPTL4 in hypoxi

98 related biological functions (p < 0.025) and angiogenic factors that have been associated with recurr

99 secretory phenotype (SASP) that includes pro-angiogenic factors that promote tumor vascularization, w

100 r up-regulated the protein expression of pro-angiogenic factors VEGFA (vascular endothelial growth fa

101 , miR-15a/16-1 translationally represses pro-angiogenic factors VEGFA, FGF2, and their receptors VEGF

102 h4.The regulative effects of TRIM28 on these angiogenic factors were partially mediated by hypoxia-in

103 Erythropoietin (EPO) is one of the systemic angiogenic factors, and its role in ocular angiogenesis

104 iators, including growth factors, cytokines, angiogenic factors, and other mitogenic pathways.

105 In line with increased angiogenic factors, conditioned media from RAB11B-AS1-ov

106 lls lacking Flvcr2 had altered expression of angiogenic factors, failed to adopt tip cell properties,

107 a modulated a couple key angiogenic and anti-angiogenic factors, resulting in an enhanced anti-angiog

108 CB2, show compromised PDZ with dysregulated angiogenic factors, resulting in the retention of blood

109 and decreased expression of two critical pro-angiogenic factors, vascular endothelial growth factor A

110 ling axis of p-p38/p-MAPKAPK2, NFkappaB, and angiogenic factors, which were downregulated by HI.

111 suppresses decidualization and misregulates angiogenic factors.

112 iple inflammatory cytokines, chemokines, and angiogenic factors.

113 thmatic airways via modulating pro- and anti-angiogenic factors.

114 he imbalance between pro-angiogenic and anti-angiogenic factors.

115 ocess is further triggered by the release of angiogenic factors.

116 orrelated with decreases in infarct size and angiogenic findings in the striatum.

117 The latter exerts high angiogenic function through both autocrine and paracrine

118 arization largely by paracrine activation of angiogenic functions in the peri-ischemic vasculature.

119 al sequence of peptide ephrinB2/CTF2 rescues angiogenic functions of brain ECs expressing PS1 FAD mut

120 mutations impede the EphB4/ephrinB2-mediated angiogenic functions of ECs and impair brain neovascular

121 receptor beta/delta (PPARbeta/delta) has pro-angiogenic functions, but whether PPARbeta/delta modulat

122 icantly upregulated genes, the levels of pro angiogenic genes such as early growth response (EGR3), p

123 reased angiogenesis and decreased amounts of angiogenic GFs in the wound.

124 Pro-angiogenic GPCR ligands were expressed by patient-derive

125 s IL (interleukin)-10 and TGF-beta1, and the angiogenic growth factor VEGF (vascular endothelial grow

126 er oligosaccharides, allowing for release of angiogenic growth factors promoting tumor development an

127 e upregulation of the downstream pathway and angiogenic growth factors via NFkappaB can be inferred t

128 Activity of alternative pro-angiogenic growth factors, acting via RTK or G-protein c

129 Pathways implicate neurotrophic and angiogenic growth factors, gonadal hormone receptors, an

130 RP1, NRP2) are receptors for semaphorins and angiogenic growth factors, while the GAIP interacting pr

131 We found that the angiogenic growth of CNS blood vessels in the brain of M

132 tigations of emergent inter- and intra-tumor angiogenic heterogeneity necessitate 3D microvascular da

133 eased intestinal expression of glycolytic or angiogenic HIF2alpha target genes.

134 AG-30/5C is an angiogenic host defense peptide that activates human mas

135 Herein, we tested whether the angiogenic imbalance and oxidative stress in the preecla

136 apeutic strategies directed at restoring the angiogenic imbalance observed during pre-eclampsia.

137 rference in apoptosis/growth/metabolism, and angiogenic imbalance.

138 Moreover, gipc mutant fish show angiogenic impairments that are ameliorated by reducing

139 Angiogenic indices, including proliferation, migration,

140 onded with poor survival and correlated with angiogenic indices.

141 lysis showed that both ID2 and Cysteine-rich angiogenic inducer 61 (CYR61) expression levels were inc

142 ssue growth factor (CTGF), and cysteine-rich angiogenic inducer 61 (CYR61).

143 ral pro-angiogenic ELR+ chemokines and other angiogenic inducers during osteogenesis indicates the po

144 ionality is impaired, and when combined with angiogenic inhibition, it can provide another mechanism

145 current or previous treatment with a BMA or angiogenic inhibitor, (2) exposed bone or bone that can

146 We assessed the heterogeneous angiogenic landscape from the microvascular to tumor ens

147 However, tumor overproduction of pro-angiogenic ligands can overcome these therapies, hamperi

148 Knockdown of DDB2 enhances the expression of angiogenic markers and promotes tumor growth in a xenogr

149 s, integrins, ADAMTSs) and the expression of angiogenic markers during the osteogenesis of ASCs.

150 SIRT1 by selisistat EX527 blunted UA-induced angiogenic markers in C2C12 cells.

151 with decreased expression of endothelial and angiogenic markers in kidney grafts as well as structura

152 Angiogenic markers such as VEGFA and CDH5 which were blu

153 es, by detecting the expression of ISL2, the angiogenic markers vascular endothelial growth factor (V

154 Furthermore, our data reveal a novel brain angiogenic mechanism targeted by PS1 FAD mutants and a p

155 onstrated by changes in pro-inflammatory and angiogenic mediators.

156 itudinally assessed circulating mediators of angiogenic, metabolic, and inflammatory pathways during

157 quantifying the hemodynamic landscape within angiogenic microenvironments.

158 cancer (CRC) patients treated with the anti-angiogenic molecule aflibercept, and the other for tripl

159 Local treatment with pro-angiogenic molecules has been the most common approach.

160 types of cancer cells, immune cells, stroma, angiogenic molecules, and the vasculature.

161 Bevacizumab (Avastin(R)), an anti-angiogenic monoclonal antibody, has been used to decreas

162 ve analysis elucidates the plasticity of the angiogenic morphogenesis in the presence of diverse and

163 in analysis identified an activation of anti-angiogenic mTOR effectors.

164 y mediators mobilizes immune-suppressive and angiogenic myeloid cells, emerging studies reveal that I

165 e tumours and are also being engineered with angiogenic, neurotrophic and anti-inflammatory molecules

166 member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities.

167 while bcar1-/- zebrafish showed no arterial angiogenic or heart defects during development, they str

168 iptional regulator of LPS-induced downstream angiogenic or vasculogenic genes.

169 s of PC, the level of several genes encoding angiogenic/osteoclastogenic pathway effectors correlated

170 In addition, critical angiogenic oxidative stress and inflammatory factors rep

171 tro assay revealed the downregulation of the angiogenic pathway by CXCR2 knockdown and p38 inhibition

172 out the prognostic role of hypoxia-inducible angiogenic pathway in G-AgP.

173 nants of response to combined PD-1/PD-L1 and angiogenic pathway inhibition and may aid in the develop

174 Hypoxia-inducible angiogenic pathway involving hypoxia inducible factor-1

175 ment of therapeutic strategies targeting the angiogenic pathway.

176 hway Analysis (IPA) revealed upregulation of angiogenic pathways upon UA supplementation in murine mu

177 le ATP and NAD(+) levels causing upregulated angiogenic pathways via a SIRT1-PGC-1alpha pathway.

178 e tumor cell invasion and induce alternative angiogenic pathways.

179 lating epithelial-mesenchymal transition and angiogenic pathways.

180 age of ephrinB2 and reduce production of the angiogenic peptide ephrinB2/CTF2, the VE-cadherin angiog

181 ts suggest hypoxia and MM cells induce a pro-angiogenic phenotype in Ocys via Fgf23 and Vegf-a signal

182 Angiogenic placental growth factor (PlGF) concentrations

183 vel therapeutic modality to provide superior angiogenic potency to bone marrow-derived stem cells (BM

184 arrier formation (EV-miR-21) and rescued the angiogenic potential (HDL-miR-132) of ECs cultured in se

185 e for AXL/S100A10 signaling in mediating the angiogenic potential of ccRCC cells and support the comb

186 role for GAS6/AXL signaling in promoting the angiogenic potential of ccRCC cells through the regulati

187 of CNP and NPR-C, but not NPR-B, reduces the angiogenic potential of pulmonary microvascular endothel

188 e transfected with miR-214-3p, decreased the angiogenic potential.

189 vival, and vasoconstriction while decreasing angiogenic potential.

190 e corneal epithelium is important for (lymph)angiogenic privilege, whereas the limbus does not act as

191 ry protein that promotes corneal immune- and angiogenic-privilege.

192 We investigated the role of CRBN in the angiogenic process and in propagating the antiangiogenic

193 tissue analysis found the coexistence of an angiogenic process combined with endothelial microchimer

194 This review provides a broad overview of the angiogenic process during cutaneous wound healing and th

195 inephrine and epinephrine mostly inhibit the angiogenic process in cutaneous wounds, dopamine, the ot

196 pamine D2 receptors negatively regulates the angiogenic process in normal dermal wounds and thereby d

197 3, a molecule observed to be involved in the angiogenic process of several malignancies.

198 modulatory potential of sGAG derivatives on angiogenic processes and point towards their prospective

199 inoglycans (GAG) are important regulators of angiogenic processes.

200 onal antibody, has been used to decrease the angiogenic profile.

201 Overall, we demonstrate that ISEMFs possess angiogenic properties as evidenced by their ability to r

202 quently abolished EC differentiation and the angiogenic properties of endothelial cell-conditioned me

203 -EFNB2 signaling stimulates the invasive and angiogenic properties of endothelial cells.

204 t this nano-VEGF has potent neurotrophic and angiogenic properties, is well-tolerated, and leads to f

205 exhibit anti-inflammatory, antioxidant, and angiogenic properties.

206 n was observed, as indicated by impaired pro-angiogenic properties.

207 ation and increased levels of sFLT1, an anti-angiogenic protein implicated in causing the maternal sy

208 Thrombospondin-4 (TSP4) is a pro-angiogenic protein that has been implicated in tissue re

209 stigate the association between a novel anti-angiogenic protein, FK506-binding protein like (FKBPL),

210 d in vitro angiogenesis and up-regulated pro-angiogenic proteins expression after oxygen-glucose depr

211 in vitro angiogenesis and down-regulated pro-angiogenic proteins expression.

212 findings demonstrate MDSC as a critical anti-angiogenic regulator during transplantation.

213 uses a restoration of fatigue resistance via angiogenic remodelling.

214 cardiac macrophage polarization toward a pro-angiogenic, reparative phenotype.

215 Collectively, our results illustrate that an angiogenic repressive lncRNA, LINC00313, which is upregu

216 Angiogenic rescue experiments in ventricular explants, o

217 downstream targets, cell proliferation, the angiogenic rescue program, hypoxia, invasion, and metast

218 a critical role for Slug in determining the angiogenic response during development and disease.

219 mesenchymal-to-endothelial transition in the angiogenic response is controversial.

220 whereas loss of Wnt7a/b function blunted the angiogenic response to hypoxia, resulting in severe whit

221 The angiogenic response to ischemia restores perfusion so as

222 appa B), HIF (hypoxia-inducible factor), and angiogenic response were prevented by Arf6 siRNA and Sec

223 lasts which seem poised to contribute to the angiogenic response.

224 roving cellular entry and eliciting a potent angiogenic response.

225 Angiogenic responses are a central aspect of wound heali

226 -5p and miR-324-5p reduces proliferative and angiogenic responses in patient-derived cells and attenu

227 olloidal gels can be used to interrogate the angiogenic responses of ECs and can be developed as a bi

228 e to insulin participates in insulin-induced angiogenic responses of endothelial cells.

229 f transcriptional activators is required for angiogenic responses.

230 To study the angiogenic role of HIF1A, and specifically probe whether

231 Tumours of obese patients showed higher angiogenic scores on gene-set enrichment analysis-derive

232 tive patients first line), ramucirumab (anti-angiogenic second line), and nivolumab or pembrolizumab

233 r structure or function, including decreased angiogenic signaling and vascular endowment, impaired va

234 vivo or in vitro inhibited inflammatory and angiogenic signaling determined by decreased activation

235 a novel regulator of sepsis-induced deviant angiogenic signaling in mouse lung EC and human fetal HP

236 /or interactions with MM cells increases pro-angiogenic signaling in Ocys.

237 ted receptor tyrosine kinase involved in pro-angiogenic signaling in physiological and pathological c

238 tion capacity, alters the gene expression of angiogenic signaling pathways such as VEGFR2, Akt, mTOR,

239 ggest that increased potassium secretion and angiogenic signaling represent early kidney responses in

240 ies an intrauterine phase with inhibition of angiogenic signaling, and a postnatal phase with proteol

241 C) cholesterol and PI(4,5)P(2) distribution, angiogenic signaling, and angiogenesis.

242 endothelial growth factor receptor-mediated angiogenic signaling, little is known about the EC-deriv

243 ar microenvironment and sequestration of pro-angiogenic signaling, may connect ADC phenotypes to surv

244 entity but instead seem to feature exuberant angiogenic signaling.

245 VEGF-exacerbated defects in angiogenesis and angiogenic signaling.

246 5)P(2) homeostasis and cholesterol-dependent angiogenic signaling.

247 gulation drive multifactorial aberrations in angiogenic signals and metabolism.

248 med during intracellular transduction of pro-angiogenic signals in endothelial cells (EC), thus harne

249 helial barrier integrity and in responses to angiogenic signals that promote cell proliferation, cell

250 providing both immunosuppressive and various angiogenic signals.

251 rocyte activation, while apoE3 was linked to angiogenic signature in pericytes.

252 We also identify strong angiogenic signatures in glomerular cell types, proximal

253 kinetics of the other two pro- and all anti-angiogenic splice variants are not known.

254 monstrates that the factor confers increased angiogenic sprouting capabilities to ECFCs and can also

255 owth factor A (VEGFA)- and ANG1/2-stimulated angiogenic sprouting in endothelial spheroids.

256 required for EC polarization, migration, and angiogenic sprouting in response to Ang-1.

257 rescues gross cytoskeleton organization and angiogenic sprouting in Rudhira-depleted cells.

258 We showed that Flvcr2 was necessary for angiogenic sprouting in the brain, but surprisingly disp

259 Angiogenic sprouting is a critical process involved in v

260 Consistently, TRIM28 knockdown inhibited angiogenic sprouting of cultured endothelial cells (ECs)

261 that P130Cas mediates Bmp2b-induced ectopic angiogenic sprouting of ECs in the developing embryo and

262 ibition of VEGF signaling prevents excessive angiogenic sprouting of Slug overexpressing EC.

263 2 controls a signaling pathway important for angiogenic sprouting that links focal adhesions to polar

264 show that Ang-1 triggers EC polarization and angiogenic sprouting through PAK2-dependent paxillin act

265 rmed a perineural vascular plexus from which angiogenic sprouts originated and penetrated the neuroep

266 in different diseases such as cancer in the angiogenic stage.

267 ignaling and promote upregulation of the pro-angiogenic STAT3 target genes IL8 and HIF1A in immune ce

268 ignaling functions to drive ECs into such an angiogenic state.

269 PET/CT imaging may provide insight into the angiogenic status and treatment response of AVMs.

270 f the peripheral avascular retina to inhibit angiogenic stimuli to anti-VEGF agents, which inhibit pa

271 the nucleus to the cytoplasm in response to angiogenic stimuli.

272 promotes vascular leakage following corneal angiogenic stimulus.

273 mphoma cells were sufficient to activate the angiogenic switch in lymph nodes.

274 This angiogenic switching appears to be caused by myeloid-der

275 However, we observed changes suggesting angiogenic switching in the mouse lungs prior to arrival

276 Anti-angiogenic therapies have generated significant interest

277 as essential to this purpose, thus far, anti-angiogenic therapies have shown only modest efficacy in

278 issue stiffness improves the outcome of anti-angiogenic therapy and prolongs patient survival.

279 Current anti-angiogenic therapy for cancer is based mainly on inhibit

280 further investigation and modulation of anti-angiogenic therapy in GBM.

281 de significantly improved evaluation of anti-angiogenic therapy response as compared with conventiona

282 8K signaling axis, providing new targets for angiogenic therapy to promote tissue repair.

283 l trials that have evaluated the efficacy of angiogenic therapy to revascularize the infarcted heart

284 d growth, alone and in combination with anti-angiogenic therapy.

285 mechanical overload stimulus indicates that angiogenic treatments to alleviate microvascular rarefac

286 Immunotherapies and anti-angiogenic treatments, which target the tumor-interactin

287 l cancer patients who are responding to anti-angiogenic treatments.

288 Depletion of ORP2 from ECs inhibits their angiogenic tube formation capacity, alters the gene expr

289 Kaposi's sarcoma is a highly angiogenic tumor that arises from endothelial cells.

290 ations that in mouse and human expresses pro-angiogenic/tumorigenic genes.

291 hese results suggest that the - A(165b) anti-angiogenic variant would preferentially bind VEGFR2.

292 We further demonstrated that the anti-angiogenic variant, VEGF-A(165b) selectively prefers VEG

293 r disease, including VEGF-A(121) and an anti-angiogenic variant, VEGF-A(165b).

294 doppel, which is expressed on the surface of angiogenic vascular endothelial cells, but is absent in

295 ression analysis revealed elevated levels of angiogenic vascular endothelial growth factor in the clo

296 reased anti-inflammatory IL-10, IL-4 and pro-angiogenic VEGF production, indicating a direct role of

297 d with significant upregulation of pro(lymph)angiogenic VEGF-A, VEGF-C, VEGF-D and infiltration of ma

298 The angiogenic VEGFA-MEF2 regulatory pathway is predominantl

299 Conversely, a subset of angiogenic venous capillary ECs and respective resident

300 long with other HHV-8 proinflammatory and/or angiogenic viral proteins, in HHV-8-associated Kaposi's