ライフサイエンスコーパス: anorectal

1 Primary sites included 113 (21%) anorectal, 178 (32%) urogenital, 206 (38%) naso-oral and

2 milar oropharyngeal (36.4vs.37.3;p=0.13) and anorectal (34.2vs.33.9;P=0.19) Cq values.

3 most common lesion locations were genital or anorectal (35 [64%] of 55 cases with available data).

4 te urethral tubularization (hypospadias) and anorectal abnormalities are two common and poorly unders

5 nterior meningocoele, presacral teratoma and anorectal abnormalities constitutes the Currarino triad

6 in, odynophagia, penile oedema, and skin and anorectal abscesses.

7 of the nRO significantly reduced spontaneous anorectal activity when compared to baseline contraction

8 We aimed to investigate anorectal pressures, anorectal and abdominal motion, and evacuation simultane

9 quenced and compared the genomes of clinical anorectal and cervical isolates belonging to serovars E,

10 her isolated or coordinated malformations of anorectal and external genital organs provides a new too

11 Congenital malformations of anorectal and genitourinary (collectively, anogenital) o

12 ints can account for the association between anorectal and genitourinary defects.

13 ring the anogenital phase causes coordinated anorectal and genitourinary malformations, whereas inact

14 stigating normal and abnormal development of anorectal and genitourinary structures.

15 The clinical treatment of patients with anorectal and pelvic floor dysfunction is often difficul

16 st-effective procedure for the evaluation of anorectal and pelvic floor dysfunction.

17 For MSMTW, two site anorectal and pharyngeal testing versus single site anor

18 For MSMTW, two-site anorectal and pharyngeal testing vs single-site anorecta

19 en shown to cause bifid nose with or without anorectal and renal anomalies (BNAR) syndrome and Manito

20 ceptible to gastric (cardia-antrum section), anorectal, and acute systemic (intravenous challenge) ca

21 important for murine resistance to gastric, anorectal, and acute systemic candidiasis.

22 mance related to types of practice (general, anorectal, and colorectal), levels and types of Board ce

23 ncreased rectal pressure (propulsive force), anorectal angle (puborectalis relaxation), and anorectal

24 ia were demonstrated for measurements of the anorectal angle and anorectal junction during liquid med

25 pressure, anorectal descent, and widening of anorectal angle independently predicted evacuation (P <

26 le plays an integral role in maintaining the anorectal angle.

27 (3) Surgery can correct minor congenital anorectal anomalies by identifying the external sphincte

28 typic variability in constipated patients by anorectal assessments.

29 cleft lip with cleft palate (aOR = 1.23) and anorectal atresia/stenosis (aOR = 1.40).

30 ation of the aorta, cleft lip, cleft palate, anorectal atresia/stenosis, and limb reduction (upper li

31 ects, hip dysplasia, limb reduction defects, anorectal atresia/stenosis, gastroschisis, hydrocephalus

32 Moreover, the anorectal bacterial load was actually lower in the shedd

33 oidal disease (HD) is one of the most common anorectal benign disorder affecting millions of people a

34 etry (ARM) parameters and physiotherapy with anorectal biofeedback (BF) treatment.

35 Anorectal biofeedback for children has been proposed, bu

36 Anorectal biofeedback therapy is effective for managing

37 We collected anorectal biopsies and swabs from 55 men who have sex wi

38 ining, incomplete evacuation, and a sense of anorectal blockage are just as important as decreased st

39 of EUS and MRI for loco-regional staging of anorectal cancer after neo-adjuvant therapy.

40 (eight with esophageal cancer and eight with anorectal cancer).

41 ents in either cohort), followed by skin and anorectal cancer.

42 r the improved detection of genital tract or anorectal carriage of group B streptococci (GBS) in preg

43 Anorectal cases may be a common gateway to the opioid ep

44 l evaluation suggested no cause, or a benign anorectal cause, of bleeding.

45 nal strategies to improve early detection of anorectal chancres, to reduce their duration of infectiv

46 nal strategies to improve early detection of anorectal chancres, to reduce their duration of infectiv

47 95% CI 30.7-32.7), with the highest rate for anorectal chlamydia (11.6 cases per 100 person-years, 95

48 sed to identify determinants associated with anorectal chlamydia and gonorrhea.

49 orted anal sex or symptoms is used to manage anorectal Chlamydia trachomatis (chlamydia) and Neisseri

50 rred at baseline and quarterly for syphilis, anorectal chlamydia, and anorectal gonorrhoea.

51 testing is a suboptimal control strategy for anorectal chlamydia, as we found a high prevalence in wo

52 % CI, 2.8-75.0], respectively), but not with anorectal chlamydia.

53 Of all anorectal chlamydia/gonorrhea cases, 72% (n = 92)/33% (n

54 Overall anorectal chlamydia/gonorrhea positivity was 13.4% (n =

55 Detection of vaginal-anorectal colonization with group B streptococci (GBS) i

56 f the body plan including the urogenital and anorectal complex, and the perineum region.

57 Hemorrhoidal disease is a highly prevalent anorectal condition causing substantial discomfort, disa

58 nternal anal sphincter tone is important for anorectal continence.

59 neurons which may be involved in control of anorectal contractions (mediated via the pelvic nerve),

60 Previous research has demonstrated that anorectal contractions in the rat are modulated by activ

61 Anorectal contractions were measured by a fluid-filled m

62 ulation sites outside the nRO did not affect anorectal contractions when compared to either (a) the 1

63 e more likely than the rostral nRO to reduce anorectal contractions.

64 the minimum effective parameters to maximize anorectal contractions.

65 well as suitability for accurate tracking of anorectal contractions.

66 companied by cardiac, cerebral, skeletal and anorectal defects.

67 orectal angle (puborectalis relaxation), and anorectal descent (perineal relaxation)-determine evacua

68 l and anal pressures increased concurrently; anorectal descent followed.

69 tory and evacuation phases, rectal pressure, anorectal descent, and widening of anorectal angle indep

70 nal wall expansion that was coordinated with anorectal descent, increased rectal and anal pressure, a

71 ), which are arguably the most common benign anorectal diseases encountered by gastroenterologists.

72 t defines criteria for diagnosing functional anorectal disorders (ie, fecal incontinence, anorectal p

73 egories of functional oesophageal, bowel and anorectal disorders, and to the specific FGIDs of IBS, f

74 has refined the diagnostic armamentarium in anorectal disorders.

75 and enhanced the diagnostic armamentarium in anorectal disorders.

76 ithholding patterns, and the implications on anorectal disorders.

77 y, pathophysiology, and management of common anorectal disorders: fecal incontinence (FI), functional

78 type (urge, passive or combined), aetiology (anorectal disturbance, bowel symptoms or both) and sever

79 cal observations suggest a wider spectrum of anorectal disturbances.

80 on of healthy women had specific patterns of anorectal dysfunction, including inadequate rectal press

81 ten experience visceral hypersensitivity and anorectal dysfunction.

82 cography) provide a refined understanding of anorectal dysfunctions and identify phenotypes in defeca

83 clinical observations indicate a spectrum of anorectal dysfunctions.

84 This study examined whether weekly digital anorectal examination (DARE) could help men self-detect

85 An annual digital anorectal examination may be useful for early detection

86 Rigid sigmoidoscopy and an anorectal examination were also used to examine symptoma

87 Screening included anal cytology and digital anorectal examination, and, if results of either were ab

88 ntinence as well as for patients who require anorectal excision for low-lying malignancy.

89 in cis women and non-binary individuals and anorectal features predominated in trans women.

90 d with radical surgery, and thus to maintain anorectal function and quality of life.

91 Although anorectal function is transiently somewhat impaired afte

92 making; follow-up schedules; use of specific anorectal function tests; and quality of life and patien

93 sociated with substantial morbidity (loss of anorectal function with a permanent colostomy and a high

94 41 patients with cloacal exstrophy to assess anorectal function, urinary continence, and sexual funct

95 on) and to diagnose problems with bladder or anorectal functioning.

96 e tests to rule out serious diseases; assess anorectal functions, which are discussed in detail; and

97 has been developed to improve measurement of anorectal functions.

98 symptoms were independently associated with anorectal gonorrhea (odds ratios [ORs], 3.3 [95% confide

99 could be an appropriate control strategy for anorectal gonorrhea, as few infections would be missed.

100 .5 cases per 100 person-years, 9.9-11.1) and anorectal gonorrhoea (9.7 cases per 100 person-years, 9.

101 terly for syphilis, anorectal chlamydia, and anorectal gonorrhoea.

102 gue rate index, capacity to sustain); cough (anorectal gradient pressure); push (rectum-anal gradient

103 Anorectal HIV RNA shedding during effective ART was not

104 n blood and prevents transmission, low-level anorectal HIV RNA shedding persists in some ART-treated

105 Unexpectedly, we found no evidence that anorectal HIV shedding was associated with the parameter

106 .8) were diagnosed with syphilis-one primary anorectal infection detected by DARE, two secondary infe

107 oradic cases of meningococcal urogenital and anorectal infections, including urethritis, proctitis, a

108 Genital or anorectal involvement was reported in 13 (68%) of 19 cas

109 um abdominosacral distance, rectal pressure, anorectal junction descent, anal diameter) and correlate

110 uring simulated defecation, rectal pressure, anorectal junction descent, and abdominopelvic-rectoanal

111 for measurements of the anorectal angle and anorectal junction during liquid medium voiding.

112 al 1.00-8.11) and a distal (</=3 cm from the anorectal junction on magnetic resonance imaging) tumor

113 zones of other mouse tissues (including the anorectal junction) as well as in the gastro-oesophageal

114 on staging MRI, low rectal tumor <2 cm from anorectal junction, and laparoscopic transabdominal post

115 ated with tumors located up to 1 cm from the anorectal junction, anterior tumors, cT4 tumors, extra-m

116 neo-epithelium of the colon (SNEC), near the anorectal junction.

117 ported receptive anal sex than those without anorectal lesions (adjusted OR, 14.4 [95% CI, 1.0-207.3]

118 Case patients with anorectal lesions more commonly reported receptive anal

119 rineal descent during evacuation (factor 1), anorectal location at rest (factor 2), and anal resting

120 Anorectal malformation (110, 89.4%) was the most common

121 We aimed to study the impact of anorectal malformation (ARM) type and sacral ratio on co

122 oversial aspects of caring for patients with anorectal malformation and offer insights into various m

123 Anorectal malformations (ARM) are rare congenital anomal

124 Anorectal malformations are uncommon but complex congeni

125 This results in severe anorectal malformations characterized by an absence of t

126 s in Bmp signaling are one possible cause of anorectal malformations during human embryogenesis.

127 Anorectal malformations have been recognized and managed

128 udies, abdominal wall defects in 27 (52.9%), anorectal malformations in 24 (47.1%), and Hirschsprung'

129 Management of anorectal malformations requires an accurate clinical di

130 nital abnormalities, including malrotations, anorectal malformations, and tracheoesophageal fistula a

131 scribes recent advances in the management of anorectal malformations, including prenatal diagnosis, n

132 tion in postsurgical functional outcomes for anorectal malformations.

133 tion surgery and its correlation to baseline anorectal manometry (ARM) parameters and physiotherapy w

134 nosed on the symptom pattern supplemented by anorectal manometry (ARM), the balloon expulsion test (B

135 FGID patients who underwent high resolution anorectal manometry (HR-ARM) and balloon expulsion test

136 High-resolution anorectal manometry (HR-ARM) and fluoroscopic defecograp

137 The utility of high-resolution anorectal manometry (HR-ARM) for diagnosing defecatory d

138 High-resolution anorectal manometry (HRAM) has been developed to improve

139 Anorectal manometry and imaging are useful for evaluatin

140 laxatives and anti-diarrhoeal agents) fail, anorectal manometry and other tests (endoanal imaging, d

141 nd validated and high-resolution colonic and anorectal manometry as well as the barostat, despite the

142 ore, Fecal Incontinence Quality of Life, and anorectal manometry at 3, 6, and 12 months compared to b

143 were more frequently suggested in IBS-C and anorectal manometry in FC.

144 No significant changes were detected in anorectal manometry measurements.

145 isorders are distinct or overlap is unclear; anorectal manometry might be used in diagnosis, but heal

146 arectum, degree of soiling/incontinence, and anorectal manometry profile(s).

147 m questionnaires, balloon expulsion test and anorectal manometry were done for reference.

148 ve assessment included physical examination, anorectal manometry, and anal endosonography.

149 tal pressures, measured with high-resolution anorectal manometry, and rectal balloon expulsion time i

150 al placebo plus education only, placebo plus anorectal manometry-assisted biofeedback, loperamide plu

151 dy were to compare different combinations of anorectal manometry-assisted biofeedback, loperamide, ed

152 ide plus education only, and loperamide plus anorectal manometry-assisted biofeedback.

153 h supine magnetic resonance defecography and anorectal manometry.

154 constipated patients through high-resolution anorectal manometry.

155 cipal components analysis of high-resolution anorectal manometry.

156 All anorectal measurement values were performed using the IS

157 optimal medical and surgical management for anorectal melanoma are needed to improve outcomes.

158 Anorectal melanoma is a rare malignant neoplasm with var

159 cterize changes in the surgical treatment of anorectal melanoma over time.

160 ve review was performed of all patients with anorectal melanoma treated at our institution between 19

161 45.8-74.3 years]) with histologically proven anorectal melanoma treated at our institution during a 2

162 abdominoperineal resection (APR) for primary anorectal melanoma, such an aggressive approach may be u

163 nt is not associated with outcome in primary anorectal melanoma.

164 ns occur more commonly in female genital and anorectal melanomas and CTNNB1 mutations implicate a rol

165 ty by immunofluorescence microscopy, and the anorectal microbiome by quantitative PCR and 16S rRNA ge

166 anding and treating disorders of colonic and anorectal motility and anticipate future advances.

167 n the pathophysiology and therapy of certain anorectal motility disorders associated with the IAS dys

168 arations were used to investigate changes in anorectal motility during electrical stimulation of the

169 Abdominal wall and anorectal motion, anorectal pressures, and rectal evacua

170 Therefore, the vaginal and anorectal mucosa are relevant sites for ZIKV infection.

171 e (OR, 2.4; 95% CI, 2.1-2.7), and concurrent anorectal N. gonorrhoeae (OR, 11.4; 95% CI, 10.6-12.3).

172 rrhoeae (OR2.4,95%CI2.1-2.7), and concurrent anorectal N.gonorrhoeae (OR11.4,95%CI10.6-12.3).

173 ation, of which 19% (n = 19)/0% (n = 0) were anorectal only.

174 testing, along with a substantial amount of anorectal-only infections.

175 ssociated with men who have sex with men and anorectal or oropharyngeal infections.

176 he lack of FDA-cleared NAATs with claims for anorectal or oropharyngeal samples.

177 (OS) by primary site (naso-oral, urogenital, anorectal, other), ethnicity/race (Caucasian, Asian, Oth

178 tion were pain management, mostly for severe anorectal pain (21 persons); soft-tissue superinfection

179 sorders: fecal incontinence (FI), functional anorectal pain and functional defecation disorders.

180 ctional chest pain, dyspepsia, vomiting, and anorectal pain do not appear to vary by gender.

181 Functional anorectal pain syndromes are defined by clinical feature

182 Functional anorectal pain syndromes include proctalgia fugax (fleet

183 n levator ani syndrome (LAS) and unspecified anorectal pain the pain lasts more than 30 minutes, but

184 anorectal disorders (ie, fecal incontinence, anorectal pain, and disorders of defecation).

185 ed into levator ani syndrome and unspecified anorectal pain, which are defined by arbitrary clinical

186 domized controlled trial assigned ambulatory anorectal patients to ERAS (experimental) or routine car

187 Guidelines suggest different combinations of anorectal, pharyngeal, and urogenital testing based on a

188 gnificantly following ileostomy closure, and anorectal physiological testing was unaltered following

189 Anorectal physiology studies revealed significantly lowe

190 clinical histories, anal ultrasound results, anorectal physiology studies, and responses to conservat

191 mportant to note that referring patients for anorectal physiology testing alone tended to predict poo

192 investigated with endoanal ultrasonography, anorectal physiology, and examination under anaesthetic.

193 oup to divide the cloaca into urogenital and anorectal portions, exhibit complex muscle morphology in

194 The remaining anorectal pressure profile and sensory levels were compa

195 imed to compare clinical characteristics and anorectal pressure profile in patients with HSD/hEDS to

196 These results suggest anorectal pressure profile is not compromised by connect

197 atory disorders (DDs) asynchronously measure anorectal pressures and evacuation and show limited agre

198 ur understanding of the relationship between anorectal pressures and rectal evacuation and the diagno

199 We evaluated anorectal pressures during evacuation with left lateral

200 We aimed to assess anorectal pressures in isolation and synchronously with

201 Abdominal wall and anorectal motion, anorectal pressures, and rectal evacuation were measured

202 We aimed to investigate anorectal pressures, anorectal and abdominal motion, and

203 We evaluated anorectal pressures, measured with high-resolution anore

204 py for refractory fecal incontinence and for anorectal reconstruction to avoid colostomy after abdomi

205 Loss of anorectal resting pressure due to internal anal sphincte

206 y produce a poor anal "seal" and an impaired anorectal sampling reflex.

207 Anorectal screening in women without an indication is fe

208 another testing strategy, routine universal anorectal screening with respect to chlamydia and gonorr

209 igher concentrations of the cytokine IL-7 in anorectal secretions.

210 In the recipient, the native anorectal segment was removed and the graft was transpla

211 aborate the predictive value of pretreatment anorectal sensation and the response to sensory retraini

212 The presence of some degree of anorectal sensation is the only preoperative assessment

213 ta of 263 women with at least one genital or anorectal sexually transmitted infection from a cross-se

214 ith men on effective ART, hypothesizing that anorectal shedding would be linked to microbiota-driven

215 The urogenital and anorectal sinuses develop from the embryonic cloaca, and

216 Viral DNA was found in 8 oropharyngeal and 5 anorectal specimens among 10 mpox cases confirmed by les

217 Five hundred consecutive cervicovaginal and anorectal specimens submitted for GBS culture were inclu

218 A total of 203 consecutive primary vaginal/anorectal specimens were cultured in selective Todd-Hewi

219 to highlight such advances in colorectal and anorectal surgery for IBD over the last year.

220 An ERAS protocol in ambulatory anorectal surgery is feasible, and resulted in reduced o

221 ues (31.0) followed by urine samples (32.5), anorectal swabs (34.0) and oropharyngeal swabs (36.8) (P

222 underwent high-resolution anoscopy (HRA) for anorectal swabs collection to investigate STIs and for a

223 aire, and healthcare professionals collected anorectal swabs for cytologic examination and human papi

224 er Ct values were found in oropharyngeal and anorectal swabs when corresponding symptoms were present

225 ospectively inoculated with clinical vaginal/anorectal swabs, with 500-mul aliquots collected.

226 philis during the primary stage-implies that anorectal syphilis chancres are less noticeable than pen

227 mary stage had gone undetected, implies that anorectal syphilis chancres are less noticeable than pen

228 Primary anorectal syphilis may go unnoticed in men who have sex

229 may complement routine screening for primary anorectal syphilis.

230 f-detect abnormalities indicative of primary anorectal syphilis.

231 We performed anorectal testing in 18 cis-gender men who have sex with

232 al and pharyngeal testing versus single site anorectal testing increased the proportion of individual

233 rectal and pharyngeal testing vs single-site anorectal testing increased the proportion of individual

234 Future study of anorectal testing is needed and may inform the diagnosis

235 can Gastroenterological Association (AGA) on Anorectal Testing Techniques.

236 n women both with and without indication for anorectal testing, along with a substantial amount of an

237 Anorectal tests to evaluate for defecatory disorders sho

238 bic environments, such as the urogenital and anorectal tracts.

239 ineum tissue between external urogenital and anorectal tracts; hypospadias - ectopic ventral position

240 s, a novel potential therapeutic strategy is anorectal transplantation (ATx).

241 ere evaluated in the John Radcliffe Hospital anorectal ultrasound unit.

242 maintains the structure and function of the anorectal unit is disrupted.

243 s cluster) analyses identified abdominal and anorectal variables that predicted evacuation.