ライフサイエンスコーパス: antagonizing

1 oreover, our findings support a strategy for antagonizing 5-HT1A autoreceptors for treating cocaine a

2 First, Snail promotes cell survival by antagonizing a p53-dependent death pathway because coinc

3 to mediate actin binding and assembly while antagonizing actin-capping proteins.

4 ells rounding in PC3 cells, indicating EphA2-antagonizing activity of EM2.

5 terminant that independently evolved SERINC5-antagonizing activity.

6 , not by repressing AG transcription, but by antagonizing AG activity in the center of the flower.

7 In contrast, deleting Rb1 in the antagonizing AGRP/NPY neurons shows no effects.

8 Thus, antagonizing AMIGO3 rather than LINGO-1 immediately afte

9 nstrate that all Nef proteins are capable of antagonizing ancestral Cercopithecini tetherin.

10 collagenase injection were cultured with an antagonizing antibody against CD44.

11 ated with SGE-301, despite this compound not antagonizing antibody binding.

12 This well characterized antagonizing antibody to the GIPr will be useful as a to

13 Here we describe the generation of an antagonizing antibody to the GIPr, using phage and ribos

14 rophage migration inhibitory factor (MIF) in antagonizing antimelanoma immune responses reveal that m

15 nce: namely, the threat to survival posed by antagonizing bacteria.

16 Moreover, antagonizing BAFF altered the phenotype of alveolar and

17 Antagonizing BAFF in CS-exposed mice attenuates pulmonar

18 Antagonizing BCL-2 with venetoclax derepresses this anta

19 14, which resides in the BH4 domain, thereby antagonizing Bcl-xL-Bax binding.

20 ) principal cells are capable of driving and antagonizing behaviors of opposing valence.

21 study, we show that part of the challenge in antagonizing beta-catenin is caused by its dual function

22 nonanticoagulant agents that are capable of antagonizing binding of heparin-binding pathogens to HSP

23 Wnts can also suppress lateral cell fates by antagonizing Bmp4 expression.

24 ehaved as a dominant-negative FZD5 receptor, antagonizing both canonical and non-canonical WNT signal

25 olates, such as Vpu of HIV-1DH12, capable of antagonizing both human and rhesus BST-2.

26 ARC possesses the unusual property of antagonizing both the extrinsic (death receptor) and int

27 together with Swi5-Sfr1 play a major role in antagonizing both the FANCM-family DNA helicase/transloc

28 ghts into the antiobesogenic consequences of antagonizing brain GIP action.

29 ments, we show here that SerRS intervenes by antagonizing c-Myc, the major transcription factor promo

30 Antagonizing calcium influx into the cell and into mitoc

31 Antagonizing canonical Wnt activity in CD8(+) T cell CM

32 cells, an effect that could be inhibited by antagonizing CCL22-driven chemotaxis.

33 n, KDM3A induces ovarian cancer growth while antagonizing cellular senescence by repressing the expre

34 tify non-native AHLs capable of agonizing or antagonizing CepR, and thereby QS, in a Bcc member.

35 xvirus CP77 as a unique inhibitor capable of antagonizing Chinese hamster SAMD9L (chSAMD9L).

36 DNA repair-independent function of BRCA1 in antagonizing COBRA1-dependent transcription programme du

37 hosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channel.

38 filaments for binding to cortactin, thereby antagonizing cortactin activity.

39 We determined whether antagonizing CXCR4 with POL5551 disrupts anti-vascular e

40 utcome of antipsychotic treatments, commonly antagonizing D2 dopamine receptors (D2Rs), on cognitive

41 eficial effects in vivo while simultaneously antagonizing deleterious ones.

42 72 by augmenting phosphorylation by LKB1 and antagonizing dephosphorylation by PP2C.

43 repression of proliferation-terminating (MYC-antagonizing) differentiation genes in cancer cells.

44 toma tumor suppressor, is also important for antagonizing DNA sensing.

45 s unblocked by disabling the innate response antagonizing domains (IRADs) in EBOV VP35 and VP24 by th

46 te the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by striatal

47 Antagonizing dopamine receptors in the VLS blocked the s

48 Antagonizing dynein-mediated transport can rescue this e

49 lly induced in healthy human eSCs in situ by antagonizing E-cadherin, combined with transforming grow

50 dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53-mediated responses, respe

51 action suggested the specificity of the mDia-antagonizing effect of INF2 in maintaining the lamellipo

52 ated to its editing activity, as well as the antagonizing effect of RBP binding on miRNA repression.

53 of UVRAG with RUBICON, thereby enhancing the antagonizing effect of RUBICON on UVRAG-mediated autopha

54 from LUBAC-mediated restriction through the antagonizing effects of the effector E3 ligase IpaH1.4 o

55 riments demonstrate that BS69 promotes IR by antagonizing EFTUD2 through physical interactions.

56 is responsible for the factor's activity in antagonizing eIF1 binding to the PIC.

57 Pharmacologically antagonizing either the angiotensin-converting enzyme or

58 ion increases epithelial Na(+) absorption by antagonizing ENaC ubiquitination.

59 ctivation of PP2A (here accomplished through antagonizing endogenous inhibitors) could be a novel ant

60 ed the cellular pool of available let-7, and antagonizing endogenous let-7 triggered cell proliferati

61 modulatory nucleic acids act by agonizing or antagonizing endosomal toll-like receptors (TLR3, TLR7/8

62 rachidonic acid 15-lipoxygenase (ALOX15) are antagonizing enzymes in the metabolism of hydroperoxy li

63 anism during cardiac stress, for example, by antagonizing excessive beta-AR drive.

64 hibits MRE11 binding to reversed forks, thus antagonizing excessive nascent-strand degradation.

65 Neither antagonizing extracellular CA nor blocking loading of pr

66 extracellular polysaccharides are capable of antagonizing F. graminearum and that the uronate content

67 sed with Bcl-6 at high levels to inhibit the antagonizing factor Blimp-1, but suppresses Bcl-6 by dir

68 levels of soluble VEGF receptor 1 (sFlt), an antagonizing factor to VEGF.

69 ers, we show that FBXL16 stabilizes C-MYC by antagonizing FBW7-mediated C-MYC ubiquitination and degr

70 However, antagonizing FGF9 in wild-type control hiPSCs did not al

71 binding to sialic acid, prevent FH19-20 from antagonizing FH function on cells.

72 les remain stationary with a small amount of antagonizing force generated.

73 How these apparently antagonizing forces interact in the coinfected host is p

74 subpopulations in a heterogeneous mixture by antagonizing formation of the chromatin modifier PRC2 an

75 directly by occupying the Erag enhancer and antagonizing Foxo1 binding to a consensus forkhead site

76 hort Ase1 isoforms stabilizes the spindle by antagonizing full-length Ase1.

77 but lack the menin-binding ability, thereby antagonizing full-length SON function in transcriptional

78 is mediated by multiple core components with antagonizing functions.

79 bias to the endogenous ligand by selectively antagonizing G protein signaling.

80 In nonrhythmic conditions, antagonizing GABA(A) receptors can initiate this synchro

81 mpairs ETO2-NuRD interaction and function in antagonizing gamma-globin/LCR looping.

82 of the JCI, Kaneko and colleagues show that antagonizing GIP signaling in the CNS enhances the weigh

83 ns of the PI3K gene PIK3CA was attenuated by antagonizing GLI1 and PI3K.

84 ) regulates hepatocyte glucose production by antagonizing glucagon-induced expression of the gluconeo

85 ampers neutrophil expansion and migration by antagonizing granulocyte colony-stimulating factor (G-CS

86 target gene network and test strategies for antagonizing growth of this tumor.

87 te activation of GSK3beta in beta cells, and antagonizing GSK3beta (SB216763; IC50 = 34.3 nM) rescued

88 ility, with the facilitative sites primarily antagonizing H3K27me3 and H3K9me3 deposition.

89 1000-fold less potent than fursultiamine in antagonizing hepcidin.

90 ncers, sensitize cells to PARP inhibition by antagonizing histone demethylation and obscuring epigene

91 However, antagonizing host FcgammaR activation by Rh05 was not re

92 et that can be selectively inhibited without antagonizing human BET function.

93 1(NL4-3)Vpu was reported to be important for antagonizing human BST-2, we show here that two Axxxxxxx

94 as a switch for beta1 integrin activation by antagonizing ICAP1 (Integrin Cytoplasmic Associated Prot

95 as a switch for beta1 integrin activation by antagonizing ICAP1-mediated inhibition of integrin activ

96 Antagonizing IL-1beta with Anakinra, a rheumatoid arthri

97 Antagonizing IL-4 prevented mucosal barrier disruption a

98 a previously unappreciated role of RasGAP in antagonizing indirect activation of PDGFRbeta, define th

99 confines KCC2 to the plasma membrane, while antagonizing inhibition reduces KCC2 surface expression

100 noninfectious particles and are incapable of antagonizing interferon (IFN) effectively.

101 is critical for maintaining PMN survival by antagonizing intracellular CG activity.

102 promoted antibody affinity maturation while antagonizing IRF4-driven differentiation of plasmablasts

103 B55beta promotes cyclin E1 overexpression by antagonizing its degradation and its inhibition could re

104 indicating that ADAR2 stabilizes Ctn RNA by antagonizing its degradation by PARN and HuR.

105 iptional repressor in this context, and that antagonizing its function in the diencephalon attenuates

106 itro and in vivo by binding beta-catenin and antagonizing its nuclear localization.

107 ERK induces ind by antagonizing its repression by Capicua (Cic), a transcri

108 ith phosphorylation to stabilize Smoothened, antagonizing its ubiquitination and subsequent degradati

109 MAPK overexpression or removal of CDK-5, an antagonizing kinase.

110 ote dendrite-specific pruning mainly through antagonizing Klp10A activity.

111 nistered CYM-53093 showed robust efficacy in antagonizing KOR agonist-induced prolactin secretion and

112 e chick) allows sensory organ segregation by antagonizing lateral induction and promoting commitment

113 nfection, as well as for the design of drugs antagonizing leukocidin toxicity.

114 montelukast, a marketed anti-asthmatic drug antagonizing leukotriene receptors, reduces neuroinflamm

115 e a novel avenue to bone anabolic therapy by antagonizing LRP4 sclerostin facilitator function.

116 harzianum, that act as biocontrol agents by antagonizing M. roreri.

117 Thus, strategies focused on antagonizing MCL-1 function and expression would be pred

118 Antagonizing MDM2 and MDMX to activate the tumor suppres

119 by coculture with bone marrow stromal cells antagonizing MEK-ERK dephosphorylation.

120 e domain forms a sensory complex with UzcRS, antagonizing metal dependent stimulation by virtue of it

121 ependent methylation favors proliferation by antagonizing methylation by PRMT1.

122 atement by mGluR2/3 blockade was reversed by antagonizing mGluR5, but reinstated sucrose seeking in t

123 lung inflammation, and this was restored by antagonizing miR-1.

124 Notably, antagonizing miR-10b action enhanced NKG2D-mediated kill

125 Conversely, antagonizing miR-146a (but not miR-155) heightened the s

126 Both antagonizing miR-155 to induce Bim and proteasome inhibi

127 Conversely, antagonizing miR-200 and miR-183-96-182 cluster miRNAs i

128 Antagonizing miR-33a function in GICs reduced self-renew

129 ut these effects diminish or disappear after antagonizing miR-9 (TuD).

130 intrinsically to promote GSC self-renewal by antagonizing MOF function.

131 -rich proteoglycan, inhibits tumor growth by antagonizing multiple receptor tyrosine kinases includin

132 ress tumorigenesis by directly targeting and antagonizing multiple receptor tyrosine kinases, such as

133 key survival factor in the heart by directly antagonizing necroptosis, which is critical for the main

134 These findings also suggest that drugs antagonizing NET activity, used for the treatment of hyp

135 s adverse consequences in endothelial cells, antagonizing NO production and reparative mechanisms.

136 in stabilizing selenoprotein transcripts by antagonizing nonsense-mediated decay (NMD).

137 n conjunction to promote ISC self-renewal by antagonizing Notch signaling.

138 nd propagation, suggesting drugs selectively antagonizing NR2A-containing receptors might constitute

139 y 3 independent interactions responsible for antagonizing or potentiating antibiotic activity against

140 modifications of histones are implicated in antagonizing or recruiting the de novo DNA methylation c

141 ntration-specific responses by sequestering, antagonizing, or activating regulatory proteins in respo

142 1) promotes recovery in G2-arrested cells by antagonizing p53, it is dispensable for recovery from a

143 nd ameliorates autoimmune uveitis in mice by antagonizing pathogenic Th17 responses.

144 age targeted in ABC-DLBCL transformation--by antagonizing pathways distinctive of GCB-DLBCL, includin

145 of atypical long-range projections, whereas antagonizing Pax6 function in the thalamus disrupts cTh

146 able of disrupting the PD-1/PD-L1 complex by antagonizing PD-L1 and, therefore, restores activation o

147 RK activation, which occurs independently of antagonizing phosphatase activity.

148 The inherent difficulties of antagonizing physiological effects of drugs in the centr

149 mour suppressor, thought to primarily act by antagonizing PI3-kinase signalling.

150 s their transcriptional activation activity, antagonizing PIF-induced growth.

151 onstrate that AHLs repress petiole growth by antagonizing PIF-mediated transcriptional activation of

152 This discovery suggests that antagonizing PKP2 may be a new therapeutic opportunity t

153 This is accomplished in part by antagonizing plasticity-promoting signaling pathways act

154 is that inhibition of vascular thrombosis by antagonizing platelet integrin alphaIIbbeta3 cannot be a

155 d suggest that both activities play roles in antagonizing Polycomb silencing, stimulating enhancer ac

156 tant, suggesting that H3K4me1 is involved in antagonizing Polycomb silencing.

157 cuate nucleus (ARC) in hypothalamus contains antagonizing POMC and AGRP/NPY neurons for negative and

158 choline, either lowering cholinergic tone or antagonizing postsynaptic M(1) muscarinic receptors norm

159 nd dilatation but also provide evidence that antagonizing PPARbeta/delta represents an important stra

160 at is required for osteoblastogenesis, while antagonizing PPARgamma-mediated adipogenesis.

161 R3 signaling, suggesting that this occurs by antagonizing pro-apoptotic signals induced by TNF.

162 trarenal FoxP3(+) Treg accumulation, thereby antagonizing proinflammatory CD11b(+) DCs.

163 yet recognized increased expression of genes antagonizing proinflammatory signaling and inflammatory

164 at SLX4IP favors SMX-dependent resolution by antagonizing promiscuous BLM activity during ALT recombi

165 hat in medaka, two RNA-binding proteins with antagonizing properties target this D3U-box, promoting e

166 By antagonizing RAD51 at forks, RADX allows cells to mainta

167 9, modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the confo

168 ategies rely on intraocular delivery of VEGF-antagonizing reagents, which results in sustained suppre

169 specifically within Ras-mutant cell lines by antagonizing release of negative feedback signalling, de

170 ies have also found that ISG15 is capable of antagonizing replication of some viruses in tissue cultu

171 We now report the identification of a Rho-antagonizing RNA element (RARE) that hinders Rho-depende

172 the histone octamer, but its contribution to antagonizing RNA polymerase II (Pol II) access and trans

173 odiesterase (PDE) that cleaves 2-5A, thereby antagonizing RNase L activation.

174 ns and animals, encode 2',5'-PDEs capable of antagonizing RNase L.

175 o reach and cross the spinal cord midline by antagonizing Robo1/2-mediated repulsion from midline-exp

176 quitin ligase for histone H2A, indicating an antagonizing role of BAP1 against Ring1B-Bmi1.

177 P28 and bZIP60 in plant UPR, and identify an antagonizing role of BI1 in the pro-adaptive signaling m

178 tioned in neuroprotective and muscle atrophy-antagonizing roles.

179 Antagonizing RORalpha activity may be a therapeutic stra

180 in physiological conditions and in stress by antagonizing SA-dependent growth inhibition through UPR

181 Clinical studies indicate that antagonizing serotonin (5-HT) type 3AB (5-HT(3AB)) recep

182 istone deacetylase 1 (HDAC1) recruitment and antagonizing Slug E-box binding.

183 o Carotid endothelial denudation showed that antagonizing smooth muscle cell USP20 activity increased

184 aintain totipotency and germline identity by antagonizing somatic fate.

185 inding activity directly but by functionally antagonizing Ssn6-Tup1.

186 acylhydrazones as privileged structures for antagonizing STAT SH2 domains, and demonstrates that apo

187 sive effects of p28/p40 derived in part from antagonizing STAT1 and STAT3 pathways induced by IL-27 a

188 The PRRSV-mediated antagonizing STAT3 could lead to suppression of a broad

189 25-HC acts by antagonizing sterol response element-binding protein (SR

190 Intriguingly, for each interaction the antagonizing strain was more likely to have a wider meta

191 striatal output that is acutely corrected by antagonizing striatal mGluR5.

192 d and it will be of interest to test whether antagonizing suppressive functions of CLL MDSCs could re

193 1 shuttles between the cytoplasm and nucleus antagonizing TAZ/YAP by distinct mechanisms in the two c

194 cification in the second heart precursors by antagonizing Tbx1/10-mediated inhibition of GATAa and ac

195 Together, this is consistent with ASY1 antagonizing telomere-led recombination and promoting sp

196 s the effects of glial KCC-3 on AFD shape by antagonizing the actin regulator WSP-1/NWASP.

197 ributed to its LPS-neutralizing activity and antagonizing the activation of LPS-induced Toll-like rec

198 the activation of inflammatory responses by antagonizing the activation of the NF-kappaB canonical p

199 CR) and MAPK-Erk signaling by binding to and antagonizing the activities of RAF1, BRAF, and spleen ty

200 otomorphogenesis by directly interacting and antagonizing the activity of another group of repressors

201 The strategy of antagonizing the activity of broadly acting terminal sel

202 or gene expression independently of Notch by antagonizing the activity of hypoxia-inducible factors (

203 untranslated RNAs, termed CsrB and CsrC, in antagonizing the activity of the RNA binding protein Csr

204 fies and patterns the hindbrain territory by antagonizing the activity of the spinal cord specificati

205 logs capable of either strongly agonizing or antagonizing the AgrC quorum sensing (QS) receptor in th

206 Some of these pesticides are also capable of antagonizing the androgen receptor.

207 to reactivate the p53 tumor suppressor while antagonizing the anti-apoptotic function of Bcl-2 is hig

208 cine in these models was further improved by antagonizing the anti-oxidant response.

209 ed NK cell proliferation during infection by antagonizing the anti-proliferative factor Blimp-1 (Prdm

210 usceptibility protein (BRCA1) promotes HR by antagonizing the anti-resection factor TP53-binding prot

211 Antagonizing the ATP-dependent P2X7 receptor pathway of

212 hibits efficacy comparable with SR141716A in antagonizing the basal G protein coupling activity of CB

213 5-A10, which interacts with heparan sulfate, antagonizing the binding of the virus to cells.

214 Inhibiting LTB4 synthesis or antagonizing the BLT1 receptor after zymosan challenge r

215 these studies demonstrate that specifically antagonizing the CBP/catenin interaction with ICG-001 ca

216 lizes acetylated cohesin complexes on DNA by antagonizing the cohesin release factor Wings-apart like

217 IF1alpha/VEGF-mediated tumor angiogenesis by antagonizing the crosstalk between PTMs involving HIF1al

218 ugh transcriptional positive feedback, while antagonizing the developmental networks of competing lin

219 this restriction was partially surmounted by antagonizing the DNA-dependent protein kinase (DNA-PK),

220 of hemogenic vascular niche specification by antagonizing the dorsal-ventral regulatory limits of VEG

221 2 transcription in myeloid progenitor cells, antagonizing the effect of HoxA10 on Triad1 expression.

222 Antagonizing the expression of miR-15a and miR-16, enhan

223 These results indicate that antagonizing the function of cIAPs may promote the clear

224 blocked the differentiation of TH17 cells by antagonizing the function of transcription factor RORgam

225 romoted the generation of plasma cells while antagonizing the GC fate.

226 cs for diabetes, one focus of study has been antagonizing the ghrelin system in order to improve gluc

227 Antagonizing the glucocorticoid receptor with mifepristo

228 nd other AHLs restrict petiole elongation by antagonizing the growth-promoting PHYTOCHROME-INTERACTIN

229 of 4c as an anti-obesity candidate drug via antagonizing the H3R.

230 Recently, anti-inflammatory effects in AD by antagonizing the histamine (H)-4 receptor have also been

231 viral proteins/genetic elements involved in antagonizing the host immune response.

232 domain that is important for replication and antagonizing the host innate immune response.

233 ssory protein that enhances virus release by antagonizing the host restriction factor BST-2.

234 tial role in enhancing virion infectivity by antagonizing the host restriction molecule SERINC5.

235 st shutoff by IBV plays an important role in antagonizing the host's innate immune response.

236 Antagonizing the human M3 muscarinic receptor (hM3R) ove

237 t, as well as previously identified roles in antagonizing the innate immune defenses of the cell and

238 ses acute diarrhea in swine, plays a role in antagonizing the innate response in porcine epithelial c

239 level of INS-7 from URX disrupts learning by antagonizing the insulin receptor-like homolog DAF-2 in

240 hich the modulation of TRPV1 is inhibited by antagonizing the interaction between TRPV1 and A kinase

241 umor suppressive function in the pancreas by antagonizing the metaplastic conversion of acinar cells

242 at SCCRO3 functions as a tumor suppressor by antagonizing the neddylation activity of SCCRO.

243 PSD-95 in the early-adolescent PFC, without antagonizing the NMDA receptor.

244 ing constitutive apoptosis, and importantly, antagonizing the normal pro-apoptotic effect of GCS.

245 AIP inhibits IRF7 function by antagonizing the nuclear localization of IRF7.

246 oidance responses in Arabidopsis thaliana by antagonizing the phytohormones auxin and gibberellin.

247 survival, cell growth, and proliferation by antagonizing the PI3K-AKT-mTOR pathway.

248 ancer, affects transcription via its role in antagonizing the PI3K/AKT signaling pathway.

249 s with diabetic retinopathy and suggest that antagonizing the RAAS improves patients' responsiveness

250 es mesenchymal invasion, through binding and antagonizing the RAC1-GAP protein ARHGAP24.

251 ting that IdeR induces bfrB transcription by antagonizing the repressor activity of Lsr2.

252 Compounds antagonizing the retinol-dependent interaction of retino

253 k protection complex is essential for PFA by antagonizing the Rrm3 helicase that displaces nonhistone

254 suggest that USP16 has an important role in antagonizing the self-renewal and/or senescence pathways

255 Our findings support the hypothesis that antagonizing the signaling of GHRH in T1D may improve GL

256 e were significantly reduced by functionally antagonizing the smooth muscle contraction with isoprote

257 determination and promotes proliferation by antagonizing the TGF-beta ligand myostatin.

258 7 program genes, notably Rorc and Blk, while antagonizing the transcription factor TCF1, which promot

259 , thus affecting coactivator recruitment and antagonizing the transcriptional regulation induced by 1

260 These results suggest that antagonizing the TRPV1-AKAP79 interaction will be a usef

261 put chemical screen, we found that molecules antagonizing the TRPVs (transient receptor potential van

262 lopment of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the SWI/

263 res with the base-excision repair pathway by antagonizing the uracil DNA glycosylase (Ung2) enzyme.

264 Therefore, antagonizing their effects post-radiation could increase

265 iption factors Blimp1 and Runx3 and acted by antagonizing their expression.

266 of targeting the stability of tankyrases by antagonizing their interaction with USP25 to modulate th

267 ediated adhesion of CLL cells to hyaluronan, antagonizing their motile behavior.

268 ress, and mitochondrial dysfunction, thereby antagonizing thermogenic activation of sWAT.

269 Antagonizing these adaptive responses could improve drug

270 lood-induced cartilage damage, the effect of antagonizing these cytokines was examined in human in vi

271 evelopment, and type B EAE is ameliorated by antagonizing these receptors.

272 -induced NGC during budding and suggest that antagonizing this curvature is a viable anti-influenza s

273 Because tumor IDO inhibits CD19-CARTs, antagonizing this enzyme may benefit CD19-CART therapy.

274 cooperatively facilitate KLF14 expression by antagonizing this multisubunit repressor complex in EBV-

275 taining protein alpha (SGTA) in specifically antagonizing this process.

276 Antagonizing this signalling axis allows the proto-oncog

277 g in thymocytes shapes the TCR repertoire by antagonizing thymocyte negative selection.

278 lectively, our work reveals a role of Nef in antagonizing TIM-1 and highlights the complex interplay

279 us and tumor Ag-specific CD8(+) T cells, and antagonizing Tim-3 helps restore function of CD8(+) T ce

280 otein endocytic trafficking are incapable of antagonizing TIM-mediated inhibition of HIV-1 release.

281 Therapeutically antagonizing TNF (etanercept) or S1P (JTE013) signaling

282 proliferation, we determined the outcome of antagonizing TNF-alpha in CCR5(-/)(-) mice infected with

283 to Tumor Necrosis Factor (TNF) receptors and antagonizing TNFalpha.

284 landscape and highlights the role of Uls1 in antagonizing Top2 function.

285 We initially identified apoptosis antagonizing transcription factor (AATF) to be associate

286 The activity of antagonizing transcription factors represents a mechanis

287 tate expression of these cell cycle genes by antagonizing transcriptional repression mediated by p53.

288 activation indicating that pharmacologically antagonizing TRPM3 may be a useful analgesic strategy.

289 eported to activate mTORC1 by binding to and antagonizing tuberous sclerosis complex protein 2 (TSC2)

290 ecognized role for migratory CD103(+) DCs in antagonizing type 2 immune responses.

291 sing dependent upon cGAS-STING.IMPORTANCE By antagonizing type I interferon production and action, ma

292 Antagonizing VE-cadherin widened cell-cell junctions and

293 duction of runx1+ HSPCs in the AGM region by antagonizing VEGF signaling and subsequent assignment of

294 By antagonizing Vegfa activity in explants, EMT was rescued

295 h the protein backbone that are critical for antagonizing viruses containing the Q148H and G140S muta

296 Further, antagonizing vlPAG TLR4 dose dependently prevented the d

297 AD-CT makes the FH2 domain more efficient in antagonizing with capping protein.

298 hieve such deleterious outcome in bone is by antagonizing Wnt/beta-catenin signaling.

299 Antagonizing Wnt10b signaling with DKK1 or Wnt10b antibo

300 or suppressor gene which acts by selectively antagonizing YAP-dependent tumor growth.