ライフサイエンスコーパス: apoptotic signal

1 orm ceramide-rich platforms that transmit an apoptotic signal.

2 ERK interaction for the amplification of the apoptotic signal.

3 ream of NF-kappaB activation to initiate the apoptotic signal.

4 umulated in the nucleus in the absence of an apoptotic signal.

5 leads to CAS up-regulation and amplifies the apoptotic signal.

6 same cell can block the transmission of the apoptotic signal.

7 e in the ability of cancer cells to suppress apoptotic signals.

8 ls, possibly as a result of the induction of apoptotic signals.

9 tion of proteins and sensitivity of cells to apoptotic signals.

10 known to transduce the TNFalpha-induced pro-apoptotic signals.

11 nderlying sensitivity of ago mutant cells to apoptotic signals.

12 e activation of this pathway results in anti-apoptotic signals.

13 crodomains (0.5-5-um diameter) that transmit apoptotic signals.

14 d associations with immune response and anti-apoptotic signaling.

15 -) cells show dysregulation of Bid-dependent apoptotic signaling.

16 h is known to be an important contributor to apoptotic signaling.

17 e, lipid synthesis, calcium homeostasis, and apoptotic signaling.

18 rtPA while reducing ROS and activating anti-apoptotic signaling.

19 y integral roles in mitochondrially mediated apoptotic signaling.

20 lated in Type II and downregulated in Type I apoptotic signaling.

21 hibits both death receptor and mitochondrial apoptotic signaling.

22 s Fas internalization, which is required for apoptotic signaling.

23 -1), which links the innate immune system to apoptotic signaling.

24 e against ventilationinduced hippocampal pro-apoptotic signaling.

25 tion (IR) and plays a key role in regulating apoptotic signaling.

26 ol of cell population growth mediated by pro-apoptotic signaling.

27 activation and cleavage of caspase-dependent apoptotic signaling.

28 MDM2 x CK1 complex in maintaining E2F-1 anti-apoptotic signaling.

29 otein response, essential for initiating the apoptotic signaling.

30 activating endoplasmic reticulum (ER) stress apoptotic signaling.

31 cer cells show deviant behavior that induces apoptotic signaling.

32 helial transition factor, Wnt, Hedgehog, and apoptotic signaling.

33 licate Cdc25A as a mediator of *NO-dependent apoptotic signaling.

34 nts during intrinsic (mitochondria-mediated) apoptotic signaling.

35 elocalization in a Rae1-dependent manner for apoptotic signaling.

36 -xL with Beclin1 and ultimate suppression of apoptotic signaling.

37 mic stability, ribosome biogenesis, and anti-apoptotic signaling.

38 rome c release, and activation of downstream apoptotic signaling.

39 ErbB kinase inhibitors on proliferative and apoptotic signaling.

40 omplex in TNF-induced activation of ASK1-JNK apoptotic signaling.

41 ny tend to converge toward the alteration of apoptotic signaling.

42 ressive mutation of the DR5 sites attenuated apoptotic signaling.

43 ation and for the activation of ASK1-JNK/p38 apoptotic signaling.

44 cytoskeleton and both proliferative and anti-apoptotic signaling.

45 modulation of SOCS-1 and via regulating the apoptotic signaling.

46 eclin 1 may have a direct role in initiating apoptotic signaling.

47 tutes an essential component of TNFR-induced apoptotic signaling.

48 regulates integrin-mediated pro-survival and apoptotic signaling.

49 hrough the upregulation of p53-dependent pro-apoptotic signaling.

50 PKCdelta is necessary and sufficient for pro-apoptotic signaling.

51 ed into the bloodstream but does not trigger apoptotic signaling.

52 death inducing signaling complex (DISC) for apoptotic signaling.

53 a central question in mitochondria-dependent apoptotic signaling.

54 protein-protein interactions associated with apoptotic signaling.

55 bility to drive receptor microclustering and apoptotic signaling.

56 atform for activation of caspase-2-dependent apoptotic signaling.

57 yeloid cells and regulation of the Bax/Bcl-2 apoptotic signaling.

58 secretase is necessary for p75(NTR)-mediated apoptotic signaling.

59 cell surface levels of Fas and Fas-mediated apoptotic signalling.

60 ough induction of Bcl-2 family-mediated anti-apoptotic signalling.

61 mitochondrial derived oxidative stress, and apoptotic signalling.

62 orylation (84+/-8.6% decrease) and increased apoptotic signaling (24+/-6.5-fold increase) after HPHG

63 dentifies chemical inducers of mitochondrial apoptotic signaling, a mechanism of cell death.

64 first evidence that arenaviruses can reshape apoptotic signaling according to their needs.

65 lecule responsible for the initiation of the apoptotic signal after suppression of PKCdelta activity

66 tivates AMPK and that active AMPK suppresses apoptotic signaling allowing the beta-cell to recover fr

67 c approach is indeed due to a restoration in apoptotic signaling, although the beneficial properties

68 3K, is responsible for delivering both a pro-apoptotic signal and a survival signal, the latter being

69 IRS-1 sends a strong mitogenic, anti-apoptotic signal and plays an important role in cell tra

70 need for mitochondrial amplification of the apoptotic signal and thus rescues the effect of Bid knoc

71 as a proapoptotic kinase and key mediator of apoptotic signaling and beta cell dysfunction and sugges

72 ed p75(NTR) and attenuates activation of pro-apoptotic signaling and cell death.

73 portant insights into how etoposide mediates apoptotic signaling and how targeting these pathways may

74 stimulation of betaARs to decrease cellular apoptotic signaling and normalize beta1AR expression and

75 otherapeutic agent, in an attempt to restore apoptotic signaling and overcome MDR in the human ovaria

76 inds CD37 and activates both SHP-1-dependent apoptotic signaling and PI3K-AKT-mediated survival signa

77 the crosstalk of extrinsic and mitochondrial apoptotic signaling and propose other combination therap

78 ocal GTP supply and cardiolipin transfer for apoptotic signaling and putative other functions.

79 ession facilitates the activation of JNK pro-apoptotic signaling and selectively decreases expression

80 y effects of resveratrol on inflammatory and apoptotic signaling and Sox9 expression, suggesting the

81 present understanding of the role of JNK in apoptotic signaling and the various mechanisms by which

82 diating the balance between p75(NTR)-induced apoptotic signaling and Trk-mediated survival signaling

83 manner revealing an unexpected interplay of apoptotic signalling and regulation of endolysosomal tra

84 ation of predisposed cells by inhibiting pro-apoptotic signals and activating tumor-promoting ER stre

85 ung cancer cell line conferred resistance to apoptotic signals and enhanced motility and invasion in

86 ponse in response to exercise did not induce apoptotic signals and may thus contribute to the protect

87 t TILRR similarly promotes IL-1-induced anti-apoptotic signals and reduces caspase-3 activity.

88 gnaling, a role in myocyte cell survival and apoptotic signaling, and it has been shown to be localiz

89 cell demise by inhibiting an early player of apoptotic signaling, and potentially broaden the perspec

90 on between neurons: sensitization, paracrine apoptotic signaling, and protection from such effects.

91 ory chain defect, metabolic disturbance, pro-apoptotic signalling, and oxidative stress.

92 tein cleavage sites that are elicited during apoptotic signaling are consistent with caspase-dependen

93 confirmed that genes involved in DR-induced apoptotic signaling are upregulated in the brain followi

94 t, given a variable, slowly accumulating pro-apoptotic signal arising from anti-apoptotic protein deg

95 al potentiation mechanism that amplifies the apoptotic signal as a wave.

96 echnique to measure early changes in net pro-apoptotic signaling at the mitochondrion ("priming") ind

97 bryos were studied through quantification of apoptotic signals at 24 hpf through staining with the vi

98 bryos were studied through quantification of apoptotic signals at 25 h post fertilization (hpf) throu

99 oreceptor protein that is unable to transmit apoptotic signals because it lacks most of the intracell

100 In addition, by functional measurement of apoptotic signalling (BH3 profiling) of fresh tumour and

101 most but not all neurons, indicative of anti-apoptotic signaling both upstream and downstream of this

102 arly demonstrate that the IRF-3/Bax-mediated apoptotic signaling branch contributes significantly to

103 signal, or (2) all the cells generate a pro-apoptotic signal but the majority silences this pathway

104 ar viability both by the previously reported apoptotic signaling, but also by inducing a senescence-l

105 Loss of DeltaNp63alpha occurs during apoptotic signaling by cleavage at the C terminus.

106 ide a potential target for the modulation of apoptotic signaling by effecting VDAC-VDAC and VDAC-hexo

107 risingly, LDTM exerts negative feedback over apoptotic signaling by inhibiting recruitment of the key

108 Moreover, hMOB3 negatively regulated apoptotic signaling by MST1 in GBM cells by inhibiting t

109 JNKs activate apoptotic signaling by the upregulation of pro-apoptotic

110 hat ATR inhibition reduced the activation of apoptotic signaling by these agents in non-cycling cells

111 elatively hydrophilic CLOOHs could assist in apoptotic signaling by translocating to the outer membra

112 poptotic Bcl-2 family members initiate early apoptotic signals by causing the release of cytochrome c

113 DR4, DR5, and Fas, transduce cell-extrinsic apoptotic signals by recruiting caspase-8 into a death-i

114 manifested by induction of the ER-initiated apoptotic signal C/EBP homologous protein (CHOP), ER dis

115 r target in IBC cells however increased anti-apoptotic signaling can lead to immune evasion.

116 nt transformation, our study reveals how pro-apoptotic signals can elevate ROS past a previously hypo

117 Thus, SHP regulates a mechanism by which apoptotic signals can mediate local control of mitochond

118 In the present study we report an apoptotic signaling cascade linking CK2, TTT, the PIKKs,

119 has been proposed as a primary event in the apoptotic signaling cascade.

120 diated effects on pro-proliferative and anti-apoptotic signaling cascades and protein and DNA synthes

121 The ability of SP-STP to activate pro-apoptotic signaling cascades both in the cytoplasm and i

122 ligation triggers pro-proliferative and anti-apoptotic signaling cascades.

123 ction coupling and increases proinflammatory/apoptotic signaling cascades.

124 rotein expression as well as by blocking pro-apoptotic signaling cascades.

125 isrupting membrane integrity, and initiating apoptotic signaling cascades.

126 ious stimuli by modulating calcium-dependent apoptotic signaling cascades.

127 s surrounding the position of this enzyme in apoptotic signaling cascades.

128 Exogenous IL-10 reversed all the apoptotic signaling changes induced by whole bacteria or

129 ncluding angiogenesis, antioxidant activity, apoptotic signaling, complement activation, inflammatory

130 Taken together, a Sema3A-initiated apoptotic signaling complex regulates the apoptosis of s

131 pase 8-dependent activation of mitochondrial apoptotic signaling contributes to virus-induced apoptos

132 , for low alpha-particle dose, the number of apoptotic signals decreases in the irradiated embryos an

133 NG-dependent IRF3 activation by UV is due to apoptotic signaling-dependent disruption of ULK1 (Unc51-

134 athway early in the disease process and that apoptotic signaling directly contributes to neuromuscula

135 abolishes the ability of Fas to transduce an apoptotic signal, do not develop pulmonary inflammation

136 differentially regulate the endocytosis and apoptotic signaling downstream of TNF-related apoptosis-

137 Apoptotic signalling downstream of MOMP involves cytochr

138 An example is the essential requirement for apoptotic signaling during the generation of self-tolera

139 rgy metabolism, reactive oxygen species, and apoptotic signals, enacting a significant role in normal

140 ily are known to regulate death responses to apoptotic signals, especially those originating within c

141 for the coordinated, multistep regulation of apoptotic signaling events.

142 o temporally relate virus replication to the apoptotic signaling events.

143 However, caspases also take part in non-apoptotic signalling events such as the regulation of in

144 rp1 or Parkin caused significant increase in apoptotic signaling, evidenced by increased cytochrome C

145 s hypothesis, we sought to determine the pro-apoptotic signaling factors induced by RANKL in IKKbeta-

146 ctor superfamily receptor activation, and as apoptotic signaling for some tumor necrosis factor super

147 This binding quenches apoptotic signals from activated BH3 family members.

148 FADD transmits apoptotic signals from death receptors to the downstream

149 ced subunit cross-linking could modulate JNK apoptotic signaling, further confirming the role of GST

150 Despite evidence for apoptotic signaling, hepatic cell death after APAP is ge

151 Molecular analysis revealed decreased apoptotic signaling [higher B-cell lymphoma 2 (BCL-2) an

152 CaM) has been shown to regulate DR5-mediated apoptotic signaling, however, its mechanism remains unkn

153 the inhibition of Pim1 signaling triggers an apoptotic signal in leukemic cells.

154 pharmacokinetic properties which potentiates apoptotic signaling in a manner mechanistically distinct

155 d NMII may differentially activate host cell apoptotic signaling in B1a cells.

156 d NMII can differentially modulate host cell apoptotic signaling in B1a cells.

157 We also found that EGFL6 reduced apoptotic signaling in cancer cells and promoted tumor g

158 ading to activation of caspase-dependent pro-apoptotic signaling in HeLa cells and primary human skel

159 nking endoplasmic reticulum (ER) stress with apoptotic signaling in hepatocytes.

160 A key role for JNK in pro-apoptotic signaling in hypoxic cells has previously been

161 alone could provide the initial trigger for apoptotic signaling in mammalian cells.

162 sor that plays a role during MLN2238-induced apoptotic signaling in MM cells, and these data provide

163 y of Bcl-2 family proteins, and induction of apoptotic signaling in mouse embryonic fibroblast extrac

164 Bax plays a key role in intrinsic apoptotic signaling in neurons by allowing the release o

165 e persistent virus is able to reshape innate apoptotic signaling in order to prevent interferon produ

166 The uniqueness of p53-mediated apoptotic signaling in postnatal cortical neurons was fu

167 h their interactions with cytokines, inhibit apoptotic signaling in proliferating cells of epithelial

168 s the type 2 mitochondrial pathway dominates apoptotic signaling in response to a weak death signal.

169 In this study, we investigated apoptotic signaling in response to PALA and the role of

170 ant KSR1 protein (DEVA-KSR1) exhibit reduced apoptotic signaling in response to tumor necrosis factor

171 gonucleotides (ASO) affects inflammatory and apoptotic signaling in tenocytes.

172 ion and small GTPase activation, and induces apoptotic signaling in TGF-beta1 treated HSCs.

173 This is then followed by the activation of apoptotic signaling in the CECs, which is known to lead

174 t KU55933 upregulated p53 and subsequent pro-apoptotic signaling in tubular epithelia of cisplatin-tr

175 (proNT) receptor, mediating both trophic and apoptotic signals in conjunction with p75(NTR).

176 osphatidylserine presentation in response to apoptotic signals in different tissues and during differ

177 hich in turn suppressed caspase 3/7-mediated apoptotic signals in HSG cells.

178 homologous recombination DNA repair and anti-apoptotic signals in this population.

179 y effects of resveratrol on inflammatory and apoptotic signaling including Akt activation and SCAX su

180 hway, innate immune mediators, and increased apoptotic signaling, including caspase-3 activation.

181 During apoptotic signaling induced by death receptors including

182 aspase-8 (casp8) are vital intermediaries in apoptotic signaling induced by tumor necrosis factor fam

183 gesting that this occurs by antagonizing pro-apoptotic signals induced by TNF.

184 Cell surface PS is a well-characterized apoptotic signal initiating phagocytosis.

185 n these cells, TBK1 activated NF-kappaB anti-apoptotic signals involving c-Rel and BCL-XL (also known

186 ptosis was delayed suggesting that the early apoptotic signal is initiated by NSP4 expression.

187 Compromised apoptotic signaling is a prerequisite for tumorigenesis.

188 Extrinsic apoptotic signaling is activated in reovirus-infected ne

189 These results demonstrate that DR-induced apoptotic signaling is activated in the brain following

190 Proper control of apoptotic signaling is critical to immune response and d

191 inones suppressed cell death at the level of apoptotic signal kinase-1 (ASK1) within the IRE1 pathway

192 ey primarily on endothelial cells, activates apoptotic signaling kinase 1 and nuclear factor-kappaB (

193 cultures, R1-TNF increases TNFR1, activates apoptotic signaling kinase and NF-kappaB, and promotes a

194 nd kidneys, are profoundly refractory to pro-apoptotic signaling, leading to cellular resistance to c

195 with FAS in lipid rafts support an extrinsic apoptotic signaling mechanism that is mediated by phosph

196 ates pro-oxidative, pro-inflammatory and pro-apoptotic signaling mediated by inducible nitric oxide s

197 use the RIP-Tag mouse model to show that pro-apoptotic signals mediated by the Activin B-ALK7 axis su

198 eath receptors (DRs) in addition to aberrant apoptotic signaling might confer resistance to death sig

199 stics, such as cell membrane exposure of the apoptotic signal molecule phosphatidyl serine, larger ce

200 Here we show that Pla degrades the apoptotic signaling molecule Fas ligand (FasL) to preven

201 Apoptotic signaling molecules have been identified in th

202 exposure to TNFalpha/cycloheximide or other apoptotic signaling molecules, the onset of apoptosis wa

203 In response to apoptotic signals, MTCH2 recruits tBID to the mitochondr

204 genetic or pharmacologic manipulation of the apoptotic signaling network can modify the phenotypic re

205 N-3 PUFA treatment initiated the pro-apoptotic signaling of estrogen by increasing GPER1-cAMP

206 link n-3 PUFAs biologic effects and the pro-apoptotic signaling of estrogen in breast cancer cells,

207 Apoptotic signaling of YAP2 was mediated via stabilizati

208 a unique protective effect against anti-IgM apoptotic signals on transitional B cell checkpoint, not

209 The extrusion process can be triggered by apoptotic signalling, oncogenic transformation and overc

210 ibition: (1) only a few cells generate a pro-apoptotic signal, or (2) all the cells generate a pro-ap

211 ne p53 as a new important player in the GzmB apoptotic signaling pathway and in CTL/NK-induced apopto

212 Therefore, neutralizing the CD95 non-apoptotic signaling pathway could be an attractive thera

213 ted cell death at different points along the apoptotic signaling pathway shift the signaling cascade

214 C apoptosis, and, if so, what the underlying apoptotic signaling pathway was.

215 lation of genes associated with both P38 and apoptotic signaling pathway, as well as preventing the p

216 ar and tissue levels of GPX1 activity affect apoptotic signaling pathway, protein kinase phosphorylat

217 ions, PTEN negatively regulates the AKT anti-apoptotic signaling pathway, while nuclear PTEN affects

218 K, and ATF6) and allows them to activate the apoptotic signaling pathway.

219 , we investigated the effect of erlotinib on apoptotic signal pathways in H3255 cells with the EGFR(L

220 e markedly inhibited bystander apoptosis and apoptotic signal pathways.

221 teasome inhibition include the activation of apoptotic signaling pathways and also antiapoptotic sign

222 The NS3 TCR induced a rapid expression of apoptotic signaling pathways and formation of embryonic

223 To investigate anti-apoptotic signaling pathways downstream of TNFR1, we gen

224 Infection with C parvum activated apoptotic signaling pathways in enterocytes that resulte

225 her investigation demonstrated activation of apoptotic signaling pathways in L-MDSC following STAT3 i

226 the molecular changes in STAT3, NFkappaB and apoptotic signaling pathways in pancreatic cancer cells.

227 ents a novel switch between the survival and apoptotic signaling pathways in rat CNS neurons.

228 receptor (R)1 stimulates both pro- and anti-apoptotic signaling pathways in the colon epithelium; ho

229 Bcl-XL-interacting proteins and regulate the apoptotic signaling pathways in the RPE.

230 fferent LPA receptors activate distinct anti-apoptotic signaling pathways is not yet clear.

231 Analysis of apoptotic signaling pathways revealed that ON 01910.Na i

232 Analysis of apoptotic signaling pathways reveals that TL-77 downregu

233 Analysis of apoptotic signaling pathways showed a sustained increase

234 stoma (GBM) reveals pervasive aberrations in apoptotic signaling pathways that collectively contribut

235 at Puma might be a critical component of the apoptotic signaling pathways that contribute to ventricu

236 ts into potential pharmacological control of apoptotic signaling pathways triggered by mitochondrial

237 re acutely treated with UVB (5 kJ/m(2)), and apoptotic signaling pathways were compared.

238 rapamycin (mTOR), proinflammatory, and anti-apoptotic signaling pathways, as well as downregulation

239 iptome analysis revealed that TFEB regulates apoptotic signaling pathways, especially apoptosis inhib

240 P2A in the cooperative modulation of DDR and apoptotic signaling pathways, further implicating both p

241 nd Fas regulate tyrosine phosphorylation and apoptotic signaling pathways, respectively.

242 though cnidaria are known to contain complex apoptotic signaling pathways, similar to those in verteb

243 ed hepatotoxicity and the rapid induction of apoptotic signaling pathways, the noncytotoxic T cell ac

244 ar Ca(2+) homeostasis and organelle-specific apoptotic signaling pathways.

245 lecule that participates in inflammatory and apoptotic signaling pathways.

246 to the activation of proliferative and anti-apoptotic signaling pathways.

247 rcFKs in multiple pro-proliferative and anti-apoptotic signalling pathways relating to oxidative stre

248 persistence of the stress and activation of apoptotic signaling, polyamine-depleted cells remained v

249 The resulting release of pro-apoptotic signaling proteins leads to cell destruction t

250 fect reflects the interaction SIRT1 has with apoptotic signaling proteins.

251 rinsic and death receptor-mediated extrinsic apoptotic signaling, providing a novel target for cancer

252 k between death-receptor O-glycosylation and apoptotic signaling, providing potential predictive biom

253 it functions as a pro-proliferative and anti-apoptotic signaling receptor via NH(2)-terminal domain l

254 her c-FLIP regulates mitochondrion-dependent apoptotic signals remains unknown.

255 ling for Rac activation, cell migration, and apoptotic signaling, respectively.

256 nografts induces both pro-apoptotic and anti-apoptotic signaling responses that limit cell killing, b

257 However, inhibition of apoptotic signaling resulted in the upregulation of auto

258 Stimulation of Fas leads to induction of apoptotic signals, such as caspase 8 activation, as well

259 ereas conferring susceptibility to intrinsic apoptotic signals, such as glycolysis inhibition, increa

260 p53 leads to a dose-dependent attenuation of apoptotic signaling, suggesting potential therapeutic be

261 ensitivity toward intrinsic versus extrinsic apoptotic signals suggests a critical role for this prot

262 ell lines is governed more by differences in apoptotic signaling than by differences in mitotic spind

263 the cytoplasm of nonapoptotic cells, and the apoptotic signal that activates its nuclear translocatio

264 this PPI directly triggered CASP7-dependent apoptotic signaling that bypassed the activation of the

265 RAIL) has been shown to induce mitochondrial apoptotic signaling that can be negatively regulated by

266 inflammasome was activated by mitochondrial apoptotic signaling that licensed production of interleu

267 n this review, we describe the multiple anti-apoptotic signals that have been demonstrated to be acti

268 stress-induced, p53-dependent cytostatic and apoptotic signals that would otherwise be blocked by the

269 work is due to network architecture, and the apoptotic signaling threshold is best manipulated by int

270 TSP1 activates Akt and decreases apoptotic signaling through caspase 3 and PARP1 in suspe

271 ceptor stimulation, an important process for apoptotic signaling through Fas receptors.

272 Apoptotic signaling through p75NTR requires activation o

273 IRE1alpha or PERK led to hyperactivation and apoptotic signaling through the reciprocal arm, thereby

274 Many cellular stresses are transduced into apoptotic signals through modification or up-regulation

275 that has cytoprotective functions as well as apoptotic signals through the downstream transcriptional

276 ilencing by CpG methylation provides an anti-apoptotic signal to HRS cells important in HL pathogenes

277 osis, and that oncogenic Notch overcomes the apoptotic signal to reveal an unexpected pro-proliferati

278 lated by the BCL2 family, integrates diverse apoptotic signals to determine cell death commitment and

279 he COOH-terminal domain is necessary for pro-apoptotic signal transduction occurring upon COOH-termin

280 and connects to the mitochondrial intrinsic apoptotic signal transduction pathway by the cleavage of

281 Overall apoptotic signal transduction was decreased in the thymu

282 , inducing ER stress response and activating apoptotic signal transduction.

283 e gene family that bore a unique function in apoptotic signal transduction.

284 Many pro-apoptotic signals trigger mitochondrial cytochrome c rel

285 In order to "trap" and identify the apoptotic signals upstream of mitochondrial permeabiliza

286 induced cell death depends on amplifying the apoptotic signal via caspase-8-mediated activation of Bi

287 eas homotypic E-cadherin engagement promoted apoptotic signaling via DR4/DR5, but not Fas.

288 receptor-interacting factor (NRIF) mediates apoptotic signaling via p75(NTR) in hippocampal neurons

289 ir target cells: proneurotrophins can induce apoptotic signaling via p75(NTR), whereas mature neurotr

290 pase 8 is a cysteine protease that initiates apoptotic signaling via the extrinsic pathway in a manne

291 58(IPK-/-) mice had excessive ER stress, and apoptotic signaling was activated in IECs from Atf6alpha

292 Other important regulators of apoptotic signaling were examined and found to be unpert

293 rast, reduced phosphoERK levels and enhanced apoptotic signaling were observed in cells constitutivel

294 ciency on hippocampal dopamine-dependent pro-apoptotic signaling were studied in mechanically ventila

295 pression mediated resistance to an extrinsic apoptotic signal, whereas conferring susceptibility to i

296 e propose a new mechanism of Ca(2+)-mediated apoptotic signaling whereby GM1 accumulation at the GEMs

297 class of conjugates induced regeneration of apoptotic signals, which facilitated subsequent recruitm

298 Mitotic cells are extremely susceptible to apoptotic signals, while postmitotic cells have develope

299 dependent cleavage of Bid promotes intrinsic apoptotic signaling within the brains of infected animal

300 tion and contributing to hypoxic, redox, and apoptotic signaling within the cell.