ライフサイエンスコーパス: appendiceal

1 neous melanoma = 32, cholangiocarcinoma = 3, appendiceal = 1, and breast = 1).

2 spective studies, conservative management of appendiceal abscess is recommended as a first line treat

3 Sixty adult patients diagnosed with appendiceal abscess were randomly assigned to either lap

4 ized that immediate laparoscopic surgery for appendiceal abscess would result in faster recovery than

5 s safe and feasible first-line treatment for appendiceal abscess.

6 ic invasion; n = 7), and mixed (goblet) cell appendiceal adenocarcinoids (n = 3), normal appendiceal

7 ined distinct molecular lineages of mucinous appendiceal adenocarcinoma (MAAP) from co-occurring muta

8 ase to identify patients with a diagnosis of appendiceal adenocarcinoma and at least 1 tumor marker m

9 Appendiceal adenocarcinoma is a rare tumor, and given th

10 litaxel in orthotopic PDX models of mucinous appendiceal adenocarcinoma supports the evaluation of in

11 A total of 1338 patients with appendiceal adenocarcinoma were included, with a median

12 tudy of serum tumor markers in patients with appendiceal adenocarcinoma, CEA, CA19-9, and CA125 were

13 otherapy in patients with low-grade mucinous appendiceal adenocarcinoma, patients did not derive clin

14 evidence of a metastatic low-grade mucinous appendiceal adenocarcinoma, with radiographic imaging de

15 tumor markers with survival in patients with appendiceal adenocarcinoma.

16 burden and treatment resistance in mucinous appendiceal adenocarcinoma.

17 itial workup of patients with a diagnosis of appendiceal adenocarcinoma.

18 125 were associated with overall survival in appendiceal adenocarcinoma.

19 ion regarding their utility in patients with appendiceal adenocarcinoma.

20 Appendiceal adenocarcinomas (AA) are a rare and heteroge

21 Appendiceal adenocarcinomas (ACs) are rare, histological

22 The incidence of mucinous appendiceal adenocarcinomas (MAA) has increased over the

23 Appendiceal adenocarcinomas are uncommon, and the geneti

24 of chromosome 18q loss and DPC4 mutations in appendiceal adenocarcinomas suggests involvement of DPC4

25 he DPC4 (SMAD4) and beta-catenin genes in 28 appendiceal adenocarcinomas, consisting of 17 mucinous a

26 We analyzed a total of 2469 appendiceal adenocarcinomas, of which 1375 had mucinous

27 jor prognostic impact in metastatic mucinous appendiceal adenocarcinomas, the prognostic impact of gr

28 8q (DCC and/or JV-18) in the pathogenesis of appendiceal adenocarcinomas.

29 emonstrated identical K-ras mutations in the appendiceal adenoma and corresponding synchronous ovaria

30 ied, 38% and 37% had diagnoses of metastatic appendiceal and colorectal cancers, respectively.

31 tumors, including both benign and malignant appendiceal and ovarian tumors.

32 pler waveforms were obtained from intramural appendiceal arteries identified with color Doppler imagi

33 t least 90 degrees were predictive of a high appendiceal base level with a specificity of 98% (95% co

34 to help differentiate between a high and low appendiceal base level.

35 tilt angles showed moderate correlation with appendiceal base levels (Spearman correlation coefficien

36 uate the relationship among gestational age, appendiceal base location, and cecal tilt angle.

37 The location of the appendiceal base relative to the lumbosacral spine was r

38 As a rare cancer, the evaluation of appendiceal cancer (AC) predisposition has been limited.

39 Although we estimate that around 3,000 new appendiceal cancer cases are diagnosed annually in the U

40 nalysis assessed the risk of intraperitoneal appendiceal cancer in BRCA1/2 carriers after RRBSO to de

41 ancer Database was queried for patients with appendiceal cancer undergoing surgery between 1998 and 2

42 Histologic subtypes of appendiceal cancer vary in their propensity for metastas

43 g the 694 sampled cases, 14% of patients had appendiceal cancer, 11% had primary peritoneal cancer, a

44 l neoplasm (low-grade pseudomyxoma, n = 117; appendiceal cancer, n = 57) underwent cytoreduction.

45 ancer, 10 with colorectal cancer, and 1 with appendiceal cancer.

46 e risk for nodal metastases in patients with appendiceal cancers can be quantified with reasonable ac

47 in the appendicitis-associated and malignant appendiceal carcinoids but was significantly decreased (

48 agent from 42 appendiceal samples, including appendiceal carcinoids identified at exploration for app

49 n of NAP1L1, MAGE-D2, and MTA1 compared with appendiceal carcinoids identified at surgery for appendi

50 s were higher (approximately 2-4-fold) in NE appendiceal carcinoids than in adenocarcinoids, but in G

51 osome 18q loss was present in 57% (12/21) of appendiceal carcinomas including 54% (7/13) of mucinous

52 logy, prognosis, detection and treatment for appendiceal, colonic and rectal carcinoids.

53 nd cancers such as IPMN, pituitary, thyroid, appendiceal, colorectal, etc.

54 OBJECTIVE To evaluate the impact of appendiceal computed tomography (CT) availability on neg

55 lly suspected appendicitis underwent focused appendiceal CT (5-mm section thickness, 15-cm coverage i

56 n patients with suspected appendicitis), and appendiceal CT (from data on all pelvic CT examinations

57 Appendiceal CT can be advocated in nearly all female and

58 The availability of appendiceal CT coincided with a drop in the negative app

59 endiceal CT), and 206 patients who underwent appendiceal CT in 1997 without subsequent appendectomy.

60 We performed appendiceal CT on 100 consecutive patients in the emerge

61 The effects of performing appendiceal CT on the use of hospital resources included

62 Routine appendiceal CT performed in patients who present with su

63 Appendiceal CT scans and initial reports were reviewed r

64 The interpretations of the appendiceal CT scans were 98 percent accurate.

65 After the cost of 100 appendiceal CT studies ($22,800) was subtracted, the ove

66 erwent appendectomy in 1997 (59% of whom had appendiceal CT), and 206 patients who underwent appendic

67 Before appendiceal CT, 98/493 patients (20%) taken to surgery h

68 d 97.9% specificity with focused nonenhanced appendiceal CT.

69 e dysplasia, multifocal colon cancer, and an appendiceal cystadenoma is described.

70 I, 1.01-2.31), radiographic finding of wider appendiceal diameter (OR per 1-mm increase, 1.09; 95% CI

71 graphy (CT), such as appendiceal dilatation (appendiceal diameter 7 mm), or presence of appendicolith

72 Presence of appendiceal diameter above 6.5 mm on CT, periappendiceal

73 The correlation between appendiceal diameter and Alvarado score was 78.7% (P=0.0

74 The correlation between appendiceal diameter and WBC was 80% (P=0.01 <0.05).

75 though there was a significant difference in appendiceal diameter between the patients in whom laparo

76 endiceal lumen and thickened wall (n = 5) or appendiceal diameter enlargement (n = 9).

77 An appendiceal diameter greater than 15 mm and/or a morphol

78 Our study suggests that CT findings such as appendiceal diameter less than 2.3 cm, absence of soft t

79 The optimal cut-off value of the appendiceal diameter was 6.5 mm.

80 The appendiceal diameter was greater than 15 mm (mean diamet

81 CT criteria of appendiceal diameter, presence of periappendiceal inflam

82 es available in 22 patients showed increased appendiceal diameter, wall thickening, and periappendice

83 erforation at multivariate analysis: maximum appendiceal diameter, wall thickness, loss of mural stra

84 e base of the appendix, lymphadenopathy, and appendiceal diameter.

85 Groups also differed with respect to appendiceal diameter: 15 mm +/- 4.9 for perforated appen

86 indings on computed tomography (CT), such as appendiceal dilatation (appendiceal diameter 7 mm), or p

87 decrease in surgical-pathologic severity of appendiceal disease and hospital stay.

88 orbidity, surgical approach, and severity of appendiceal disease.

89 Patients diagnosed with appendiceal goblet cell adenocarcinoma (GCA), mucinous a

90 region not typically scanned during focused appendiceal imaging.

91 as both alleles were retained in the matched appendiceal lesion, suggesting tumor progression in a se

92 points consisted of a progressively narrowed appendiceal lumen and thickened wall (n = 5) or appendic

93 efined as the conglomeration of feces in the appendiceal lumen, identify patients for whom an antibio

94 erformed to assess the diagnostic utility of appendiceal luminal diameter in differentiating differen

95 Here we describe advanced stage appendiceal MAA presenting as inguinal ulcers, scrotal a

96 ghlights a unique presentation of late stage appendiceal MAA.

97 Due to the increased incidence of appendiceal MAAs, reports of unique clinical features ar

98 e and no small bowel involvement mainly from appendiceal malignancies.

99 mutations were identified in 11 of 16 (69%) appendiceal MAs unassociated with PMP and in 12 of 16 (7

100 th appendicitis in addition to profiling the appendiceal microbiota in a population of children witho

101 ovarian and appendiceal tumors as well as in appendiceal mucinous adenomas (MAs) and ovarian mucinous

102 mucocele, mucosal hyperplasia and low-grade appendiceal mucinous neoplasm (n = 17), and those with m

103 domyxoma peritonei (PMP) originating from an appendiceal mucinous neoplasm remains a biologically het

104 Appendiceal mucinous neoplasms sometimes present with pe

105 kindred who developed a low-grade malignant appendiceal mucocele 2 years after risk-reducing salping

106 CT scans of 31 patients with diagnosis of appendiceal mucocele were retrospectively reviewed and c

107 ul in preoperative diagnosis of inflammatory appendiceal mucocele.

108 Differentiation of histologic subtypes of appendiceal mucoceles may prove to be difficult on compu

109 A total of 174 patients with epithelial appendiceal neoplasm (low-grade pseudomyxoma, n = 117; a

110 predict outcome in patients with epithelial appendiceal neoplasm undergoing cytoreduction and intrap

111 th tumor biology in patients with epithelial appendiceal neoplasm undergoing cytoreduction and intrap

112 rrent peritoneal surface dissemination of an appendiceal neoplasm.

113 intraperitoneal chemotherapy for epithelial appendiceal neoplasm.

114 arded as the standard of care for epithelial appendiceal neoplasms and pseudomyxoma peritonei syndrom

115 Twenty-six (40%) of the 65 patients with appendiceal neoplasms had presented with symptoms of acu

116 a 10-year period in 65 patients with primary appendiceal neoplasms were reviewed.

117 The outcome of patients with mucinous appendiceal neoplasms with peritoneal surface disseminat

118 not indicated after complete resection of an appendiceal NET of 1-2 cm in size by appendectomy, that

119 tumours were identified, of whom 278 with an appendiceal NET of 1-2 cm in size were included.

120 status with a histopathologically confirmed appendiceal NET of 1-2 cm in size who had a complete res

121 tomy, that regional lymph node metastases of appendiceal NETs are clinically irrelevant, and that an

122 Appendiceal NETs are usually diagnosed accidentally afte

123 Patients who underwent surgical resection of appendiceal NETs at 11 tertiary Italian centers, from Ja

124 e aimed to assess the malignant potential of appendiceal NETs of 1-2 cm in size in patients with or w

125 After centralised histopathological review, appendiceal NETs were classified as a possible or probab

126 independently related to nodal metastases in appendiceal NETs.

127 cal features related to nodal involvement in appendiceal neuroendocrine tumors (NETs), to identify pa

128 ential global overtreatment of patients with appendiceal neuroendocrine tumours (NETs) of 1-2 cm in s

129 These results indicate that the appendiceal niche harbors distinct microbial populations

130 All appendicitis and appendiceal operations reported to the National Hospital

131 For appendiceal or biliary sources of CIAI, antibiotic durat

132 CT scans were evaluated for the presence of appendiceal or other disease.

133 LNPCPs involving the ileo-caecal valve, the appendiceal orifice, and circumferential LNPCPs.

134 l after maximal surgical resection of PMC of appendiceal origin is associated with improved OS and di

135 r peritoneal dissemination from neoplasms of appendiceal origin is indicated.

136 epithelial peritoneal surface malignancy of appendiceal origin underwent surgery during a 12-year pe

137 A total of 167 PMP patients of appendiceal origin were included between 2016 and 2021.

138 8.0-66.0] years) (41.8%) had CCRS for PMP of appendiceal origin.

139 al PCI by the Bland-Altman method for PMP of appendiceal origin.

140 is 16-year review reveals evolving trends in appendiceal pathology at a tropical tertiary center, inc

141 dicitis, and determine if findings regarding appendiceal pathology hold over time.

142 cally significant independent predictors for appendiceal perforation and are associated with increase

143 quality measures, including the frequency of appendiceal perforation and ED revisits, remained stable

144 Appendiceal perforation has been associated with increas

145 The risk for developing appendiceal perforation or gangrene may be determined, i

146 Appendiceal perforation rates dropped from 22% to 14% af

147 ver, its impact on negative appendectomy and appendiceal perforation rates has not been reported.

148 The difference between the appendiceal perforation rates met the noninferiority thr

149 T) availability on negative appendectomy and appendiceal perforation rates.

150 iotic treatment did not decrease the risk of appendiceal perforation when appendectomy was performed

151 heir association with negative appendectomy, appendiceal perforation, and 3-day ED revisits.

152 f the appendix, presence of appendicitis and appendiceal perforation, and establishment of an alterna

153 and CT also was comparable for detection of appendiceal perforation, with MR imaging (n = 103) sensi

154 vals (CIs) for diagnosis of appendicitis and appendiceal perforation.

155 nosis 9 (ICD-9) codes were used to determine appendiceal perforation.

156 various findings that may be associated with appendiceal perforation.

157 Twenty-one (24%) of the 86 patients had appendiceal perforation.

158 leus (93%) had the highest specificities for appendiceal perforation; however, the sensitivities of t

159 the MUC2 expression profile also supports an appendiceal rather than ovarian origin for pseudomyxoma

160 pply in critical shortage areas could reduce appendiceal rupture and improve surgical access more gen

161 The rates of appendiceal rupture and negative appendectomy in childre

162 ed health care costs and morbidity linked to appendiceal rupture are considered preventable in most c

163 with public insurance had increased odds of appendiceal rupture compared with children who had priva

164 The rate of appendiceal rupture in school-aged children was associat

165 Recent arguments suggest that high rates of appendiceal rupture may be unrelated to the quality of h

166 ate was 3.06% (range, 1%-12%) and the median appendiceal rupture rate was 35.08% (range, 22%-62%).

167 d race, health insurance status, or hospital appendiceal rupture rate.

168 The adjusted OR for appendiceal rupture was higher in Asian children (1.66;

169 NA was isolated using TRIzol reagent from 42 appendiceal samples, including appendiceal carcinoids id

170 describe the first reported case of primary appendiceal signet ring cell carcinoma arising in a CDH1

171 As appendiceal signet ring cell carcinoma is exceedingly ra

172 Purpose To test the hypothesis that appendiceal spectral Doppler waveforms can distinguish p

173 apler is currently the most common method of appendiceal stump closure (83.6%).

174 appendiceal adenocarcinoids (n = 3), normal appendiceal tissue (n = 5), and 5 colorectal cancers.

175 Gene expression data from appendiceal tissue donors identified NEDD4L to be among

176 lso examined differential gene expression in appendiceal tissue samples between patients with AA and

177 The molecular delineation of malignant appendiceal tumor potential provides a scientific basis

178 ed States around surgical treatment of major appendiceal tumor types over time and describe differenc

179 , appendicitis specimens (n = 11), malignant appendiceal tumors (> 1.5 cm, evidence of metastatic inv

180 estinal and metastases, n=17, gastric, n=5), appendiceal tumors (n=10), and adenocarcinomas (gastric,

181 CgA identified all appendiceal tumors as well as covert lesions, which may

182 rm cases of PMP with synchronous ovarian and appendiceal tumors as well as in appendiceal mucinous ad

183 tern of allelic loss between the ovarian and appendiceal tumors at one or two of the loci tested was

184 Appendiceal tumors represent a range of histologies that

185 Most patients with appendiceal tumors undergo RHC, which is associated with

186 The mean age of all patients with appendiceal tumors was 49 years (range, 35-74 years).

187 al allelic losses in the matched ovarian and appendiceal tumors.

188 RHC should be offered selectively for appendiceal tumors.

189 - wherein the potential misclassification of appendiceal tumours as malignancies of the colon and ova

190 a consensus of core research priorities for appendiceal tumours that are poised to be ground-breakin

191 282 patients with suspected appendiceal tumours were identified, of whom 278 with an

192 delineate unique challenges for the study of appendiceal tumours, and to propose key priority researc

193 specificity, a focal defect in the enhancing appendiceal wall achieved the highest sensitivity.

194 appendicolith, and focal defect in enhancing appendiceal wall individually were 36%, 46%, 36%, 21%, a

195 A focal defect in enhancing appendiceal wall was significantly associated with perfo

196 l lymph nodes, and enhancement defect in the appendiceal wall were neither highly sensitive nor highl