ライフサイエンスコーパス: appose

1 SMNs and partition cells are less frequently apposed.

2 plex in which the active sites are optimally apposed.

3 g yeast, these antagonistic processes become apposed.

4 The 5HT3A-labeled glial processes apposed 5HT3A-immunoreactive axonal and dendritic profil

5 lutamate receptors and the properties of the apposed active zones, we investigated receptor localizat

6 ological and physiological properties of the apposed active zones.

7 are confronted with an array of hundreds of apposed active zones.

8 ous chromosomes recombine and become closely apposed along their lengths within the synaptonemal comp

9 channel dimer, the two monomers are closely apposed and interact during a cooperative gating process

10 EEM radius and P&M thickness were similar in apposed and malapposed circumferences.

11 the abaxonal surface of Schwann cell myelin apposes and adheres to the overlying plasma membrane.

12 ncentrations, to the boundary lubrication of apposing articular cartilage surfaces.

13 zed and reduced the work of adhesion between apposing asperities.

14 monstrated an over-representation of closely apposed ATF3 and NF-kappaB binding sites, which was veri

15 ad domains form a symmetric dimer of closely apposed backbones that fold back onto the rod domain, im

16 Pase ARL6/BBS3 drives assembly of a membrane-apposed BBSome coat that promotes cargo entry into cilia

17 arrel structure and ligand exchange with the apposing bilayer.

18 protein acts as a lipid coupler between two apposed bilayers and as a lipid "hole-filler," effective

19 HOPS:SNARE recognition and is lost when the apposed bilayers are dissolved in Triton X-100; it is al

20 VAMP) and binary syntaxin and SNAP 25 in the apposed bilayers resulted in a reduction in the height o

21 at enable these proteins to fuse two closely apposed biological membranes.

22 of localized pain-sensory neurons by closely apposed blood vessels.

23 blood, but the cushions function as stoppers apposing blood flow with near constant thickness.

24 EM-2-ir fibers apposed both serotonergic and nonserotonergic RVM neuron

25 barrier (BBB), which is composed of tightly apposed brain microvascular endothelial cells.

26 dendrites for interaction with UNC-5 on the apposing branch to induce mutual repulsion.

27 We found that the orexin neurons are heavily apposed by axon terminals of glutamatergic and GABAergic

28 jority of filopodia and elongated spines are apposed by axon terminals.

29 es of such dura/light-sensitive neurons were apposed by axons originating from retinal ganglion cells

30 e PSDs of asymmetric synapses, in most cases apposed by cortical terminals.

31 RVM neurons), they appear to be selectively apposed by EM-2-ir fibers.

32 ated on parts of the plasma membrane tightly apposed by glial processes.

33 where Necl-1 and -2 on the axon are directly apposed by Necl-4 on the Schwann cell; all three protein

34 of vessel length in rostral areas of the RMS apposed by neuroblasts.

35 s, in which single release sites of rods are apposed by one to three postsynaptic densities (PSDs).

36 rs of nascent postsynaptic apparatus are not apposed by presynaptic nerve terminals.

37 Both alpha- and gamma-motoneurons were apposed by S- and F-type synaptic boutons, whereas only

38 focal analysis revealed that CRH neurons are apposed by vesicular glutamate transporter 2 (VGLUT2)-co

39 wing culture, mechanical integration between apposed cartilage blocks was assessed by measuring adhes

40 e receptors (RyRs) at sarcoplasmic reticulum apposing CaV1.2 channels at t-tubules.

41 Tetrameric H-stalks may be lodged in apposed cavities of two F-trimers.

42 croglia accumulating near senile plaques and apposing CB(1) cannabinoid receptor-positive presynapses

43 ine kinase by ephrin-A1 ligands presented on apposed cell surfaces plays important roles in developme

44 ail interaction between EC1-EC4 domains from apposed cell surfaces, possibly forming a zipper-like pr

45 ed with clathrin-mediated endocytosis in the apposed cell.

46 GJ channels bridge apposing cell membranes to mediate the direct transfer o

47 distinct from two-dimensional binding across apposing cell membranes.

48 les in cis and in trans to mechanically hold apposing cell surfaces together.

49 merization of cadherin proteins presented on apposing cell surfaces.

50 ephrinA1 from a supported membrane into the apposing cell using a quantitative three-dimensional flu

51 ilic binding to another PTPmu molecule on an apposing cell was not possible, resulting in an accumula

52 d ephrinA1 is expressed on the surface of an apposing cell) provides a mechanism by which the recepto

53 formed when two hemichannels (connexons) of apposed cells dock head-on in the extracellular space.

54 hort protrusions (~3 um) between two closely apposed cells initiated fusion, but occasionally we obse

55 connexosomes) in the cytoplasm of one of the apposed cells that are degraded by autophagosomal and, p

56 forms cell surface trimers that bind between apposed cells to form hexamers.

57 ease EPSC activity, we observed that closely apposed cells were more likely to exhibit synchronized E

58 embly, including matching of FP membranes in apposed cells, reduction in the separation between FP me

59 trin can also mediate trans-adhesion between apposing cells decorated with its receptors on the condi

60 pressed by the same cell and is presented to apposing cells expressing the IL-15Rbeta/gammaC complex.

61 Direct communication of apposing cells is realized by two adjacent hemichannels,

62 embrane, and move from infected cells toward apposing cells on actin-filled membranous protrusions or

63 mbrane and egress from infected cells toward apposing cells on actin-filled membranous protrusions.

64 chored on two-dimensional (2-D) membranes of apposing cells.

65 ired connexons, with one each contributed by apposing cells.

66 red on two-dimensional (2D) membranes of the apposing cells.

67 ing in trans with N-cadherin-WT expressed on apposing cells.

68 and adhesion and merger of membranes between apposing cells.

69 olecules must reach across the space between apposing cells.

70 t in trans when expressed on the surfaces of apposing cells.

71 raction with ganglioside binding proteins on apposing cells.

72 ands (Delta-like1, Jagged1) cluster in their apposed central-supramolecular-activation-clusters (cSMA

73 We then asked if 5-HT-positive axons appose cholinergic neurons associated with motor functio

74 ove in a coordinated fashion to form closely apposed clusters in the ER and plasma membranes, thereby

75 of osteochondral blocks from each core were apposed, compressed 15%, and subjected to relative later

76 mples then transitioned to extended, tightly apposed contact zones where the two proximal membrane le

77 rms ectopic disulfide bonds in trans between apposed Cys(34) side chains that retard wrapping during

78 A disulfide bond formed between apposing cysteines ligates two C termini, serving as the

79 sicular membrane leaflet and not between the apposed cytoplasmic leaflets.

80 ERbeta-ir was in glial profiles that apposed DCX-labeled perikarya and dendrites.

81 amic acid decarboxylase (GAD)-IR in profiles apposing DMV neurons only after stimulation of the cAMP-

82 ptors were colocalized on GABAergic profiles apposing DMV neurons; the number of colocalized profiles

83 mediates a 30% stronger interaction between apposing E-cadherin molecules than when it cannot bind t

84 By closely apposing each other, the ER may serve as a direct and pr

85 moves in an ameboid fashion through tightly apposed endothelial borders and, in some cases, through

86 ive from imaginal discs, which are sacs with apposed epithelial sheets, the disc proper (DP) and the

87 Additionally, VAChT-IR presynaptic profiles apposed ERalpha-IR dendritic spines, presynaptic profile

88 This finding suggests that closely apposed factor binding sites, situated within compact ci

89 This study investigated the fusion of apposing floating bilayers of egg L-alpha-phosphatidylch

90 thin sheath of F-actin is induced along the apposing founder cell membrane.

91 The FCM-specific actin focus invades the apposing founder cell with multiple finger-like protrusi

92 Closely apposed genes in a head-to-head orientation share the sa

93 were visualised propagating between closely apposed glia and from glial cell processes to the soma (

94 nfirmed that alpha6 was expressed by closely apposed glia.

95 havbeta8 localizes to mesangial cells, which appose glomerular endothelial cells and maintain glomeru

96 increases the probability that mitochondria appose GLT-1 particles within astrocyte processes, witho

97 lease sites including active zones and their apposed glutamate receptor clusters--and the whole synap

98 neuron dendrites, and the density of fibers apposing GnRH neurons was even greater in PNA mice (56%)

99 een separated heads as compared with closely apposed heads (energy difference of 0.24 kT (where k is

100 rdinated by two His residues from diagonally apposed helices.

101 ulting in an azimuthal angular shift between apposing helices.

102 l containing one V(j)-sensitive gate in each apposed hemichannel (aHC); aHC open probability was a Bo

103 g of one hemichannel depends on the state of apposed hemichannel.

104 ion to) release of structured water from the apposed hydrophobic surfaces.

105 LTP, although noradrenergic varicosities are apposed in PF-PC contacts.

106 multiple protein-specific strata: a membrane-apposed integrin signalling layer containing integrin cy

107 lt-bridge or hydrogen-bond interactions with apposing JAM-A monomers abolishes the capacity of JAM-A

108 We hypothesize that TBs link the apposed junctional membranes together at a fixed distanc

109 the endoplasmic reticulum to plasma-membrane-apposed junctions, where it recruits and gates open plas

110 RY1 neurons forming corpuscular endings that appose laryngeal taste buds.

111 conditions, the cristae of mitochondria that apposed LD were mostly organized perpendicularly to the

112 investigated zipping dynamics and found that apposing leading edge cells come together at their apica

113 ecome glassy, and diffusion of lipids in the apposed leaflets becomes coupled across the water layer,

114 nt regions of asymmetric lipid bilayers with apposed leaflets composed of typical inner leaflet lipid

115 smatch, in which the initial response of the apposed leaflets upon quenching is to increase local asy

116 ons, thrombogenicity increased compared with apposed, length-matched controls (1.58-fold, P=0.001; an

117 Surface force measurements between apposed lipid bilayers displaying the extracellular doma

118 ion requires the alignment and fusion of two apposed lipid bilayers.

119 disruptions also relies on the fusion of two apposed lipid bilayers.

120 interfaces in the transport of water across apposing liquid menisci in osmosis membranes comprising

121 t spatial registration of all domains on the apposed membrane leafs.

122 ues where they dock with hemichannels in the apposed membrane to form cell-cell channels and, simulta

123 g factors, that is, they physically link two apposed membranes before intracellular membrane fusion.

124 ed force that mimicked the repulsion between apposed membranes being forced to fuse.

125 The Vam7p N-domain catalyzes the docking of apposed membranes by promoting transinteractions between

126 igate the distinct binding factors needed on apposed membranes for Rab effector-dependent tethering.

127 d subcellular compartments formed by closely apposed membranes from two organelles.

128 at a ring-shaped microdomain surrounding the apposed membranes of each docked vacuole, where fusion w

129 ins assemble into a "vertex ring" around the apposed membranes of tethered vacuoles before catalyzing

130 rans-SNARE complexes (SNAREs anchored to two apposed membranes).

131 RE domains from R- and Q-SNAREs, anchored to apposed membranes, assemble into four-helix coiled-coil

132 gomerizes, and inserts apolar loops into the apposed membranes, locally disturbing the lipid bilayer

133 ualize the two membrane leaflets and tightly apposed membranes, lying as close as 1.1 nm apart, by tu

134 ws regulated sterol transfer between closely apposed membranes, such as organelle contact sites.

135 bes but also on the stabilization of tightly apposed membranes, which are intermediate states in the

136 h their hydrophobic anchors spanning the two apposed membranes.

137 ally contacted cell by fusion of the closely apposed membranes.

138 on involves the regulated coalescence of two apposed membranes.

139 t distance of approximately 9 nm between the apposed membranes.

140 ARE proteins in a trans-complex, anchored to apposed membranes.

141 d microdomains around the periphery of their apposed membranes.

142 pathway at contact sites between two closely apposed membranes.

143 in-lipid interactions assist in bridging the apposing membranes before fusion.

144 al interactions between receptor clusters in apposing membranes could also be present in wild-type E.

145 that undergo conformational changes to bring apposing membranes in close contact prior to fusion.

146 assembly of coiled-coil domains arising from apposing membranes.

147 arge-bore, self-expanding metal stents/lumen-apposing metal stents alone or plastic stents combined w

148 igation or self-expanding metal stents/lumen-apposing metal stents alone, followed by direct endoscop

149 -expanding metal stents in the form of lumen-apposing metal stents appear to be superior to plastic s

150 sed at endoplasmic reticulum (ER) subdomains apposing mitochondria [i.e., the mitochondria-associated

151 Although the purposes of apposing mitochondria and ER have been described, an und

152 est that H-bonding between beta-strands from apposed molecules is likely responsible for the tight cy

153 y is able to prevent phase separation in the apposed monolayer.

154 on is able to induce phase separation in the apposed monolayer.

155 Alpha helix 1 and 1' of the apposing monomers form a solvent-accessible pocket at th

156 7% of VAChT-ir presynaptic profiles directly apposed MOR-ir axons and terminals, and there were almos

157 inal and central domain elements are closely apposed near the FKBP binding site within the RyR1 three

158 s was closely matched by activity in closely apposed nerve varicosities, suggesting EGCs were not onl

159 how that cell protrusions emanating from the apposed neural fold tips, at the interface between the n

160 less clear, activated microglia can closely appose neuronal cell bodies and displace axosomatic pres

161 In previous studies performed on black inks apposed on papyri from ancient Egypt, additional chemica

162 Thrombus apposed on stents creates large variations in drug uptak

163 roduces distinct patches of polymerized coat apposed onto the lipid bilayer.

164 concentrate in a ring at the vertex between apposing organelle membranes, the encircled area of memb

165 IP in vitro and in vivo requires two closely apposed pairs of BRCT domains at the C-terminus of hPTIP

166 leading to the formation of a set of closely apposed paranodal loops.

167 Of the plasma membrane-apposed particles, more than 90% were extrasynaptic; few

168 ceptor and Th-Notch ligands cluster in their apposed peripheral-SMAC (pSMAC).

169 orm where invaginated atrial siphon ectoderm apposes pharyngeal endoderm.

170 pore is a "Phe clamp," a heptad of narrowly apposed Phe residues (Phe-427), that catalyzes the unfol

171 rated by secretory lysosome fusion with bone-apposed plasma membrane.

172 d particles were localized at focal sites on apposed plasma membranes of cortical and thalamic dendri

173 r arrest in the mating reaction with tightly apposed plasma membranes.

174 lization of synaptic clusters that precisely appose post- to presynaptic elements.

175 tes that extrasynaptic fusion sites can have apposed postsynaptic specializations, suggesting that mo

176 Ectopic contacts contain apposed pre- and postsynaptic specializations, albeit wi

177 axons unaided but may regenerate axons into apposed predegenerated peripheral nerve grafts (PNGs).

178 defined by a dynamic actin cytoskeleton; (2) appose presynaptic dense projections; (3) localize ER an

179 The apposed presynaptic and postsynaptic membranes at this l

180 oting enhanced neurotransmitter release from apposed presynaptic terminals.

181 At first interphase, apposed pronuclei align obliquely to the animal-vegetal

182 e transporter showed that cholinergic fibers apposed putative cortically projecting GABAergic neurons

183 , we found that ArcN NPY/AgRP fibers closely appose PVN and DMH presympathetic neurons.

184 on, creating energy barriers between closely apposed rafts.

185 e found for residues L17 and V18 and for the apposed residues L34 and V36, suggesting cavities or cha

186 nterface through charge reversal mutation of apposed residues reduces oligomerization while introduct

187 longitudinal T-tubules triggers release from apposing ryanodine receptors in KO, partially compensati

188 g t-tubules, where L-type Ca channels (LCCs) appose sarcoplasmic reticulum (SR) Ca release channels (

189 ad higher risk of delayed coverage than well-apposed segments (relative risk 2.37, 95% confidence int

190 ISA segments is delayed with respect to well-apposed segments.

191 its sensor migrate independently to closely apposed sites of interaction in the ER and the plasma me

192 n the draining LN, HEV, and LV were directly apposed; some vessels appeared to express both PNAd and

193 y, EM2 and glutamate-containing varicosities appose spinal neurons that express MOR along with mGluRs

194 PX2-CT blocks pole segregation, resulting in apposing spindle poles with no evident displacement of A

195 med the lack of intact presynaptic terminals apposing spines on mature cells and on newborn neurons.

196 hat binding interactions between proteins on apposing stacked membranes of OSER structures were not o

197 ated attachment between glycan components of apposed stereociliary membranes.

198 one monomer and Glu(195) of a monomer in the apposing strand potentially fosters cross-strand stabili

199 of double-layered struts and inappropriately apposed struts at the bifurcation level in 3 of 5 cases.

200 is approach revealed a growth spurt of added apposed surface area (ASA)>200 mum2/d centered on a sing

201 because all gp120-gp41 spikes on the closely apposed surfaces of cross-linked viruses should be incap

202 ng partners are respectively anchored to two apposing surfaces (i.e., two-dimensional (2D) parameters

203 ction forces and dynamics between asymmetric apposing surfaces (including end-functionalized polymers

204 rces and binding dynamics between asymmetric apposing surfaces in terms of their chemical structure a

205 the desirable effect of preventing fusion of apposing surfaces of articulating cartilage, but has the

206 s foreign and do not merge together, whereas apposing swarms of clonal isolates merge with each other

207 sses revealed thin extensions, many of which appose synaptic profiles.

208 rofiles were significantly more likely to be apposed than nonserotonergic profiles.

209 al and at high concentrations are so closely apposed that they exhibit plasmon coupling and induce an

210 membrane regions of neighbouring cells that appose the dorsal side of the mother, which later forms

211 id receptor-immunoreactive varicosities that appose the postsynaptic membrane of these neurons.

212 nnels move from the juxtaparanodal region to appose the remaining heminodes.

213 x1 and positive elongation factor b (P-TEFb) appose the silencer and enhancer in CD4-negative thymoma

214 processes of nitrergic interneurons already apposed the somata and dendrites of SMI-32 labeled neuro

215 osome apparently causes a rearrangement that apposes the BCL9/B9L C-terminus to TCF.

216 nts (i.e., Caspr, contactin, and NF155), and apposes the inner mesaxon of the myelin sheath.

217 nally, microglial cells were frequently seen apposing the cell bodies and dendrites of auditory neuro

218 , however, within the neuropil and sometimes apposing the excitatory synapses.

219 iated with a conformational change, in vivo, apposing the promoter with its remote regulators, consis

220 n layer of peripodial epithelium (PE) and an apposing thickened layer of pseudostratified columnar ep

221 ntact the plaque of acetylcholine receptors, apposing this surface as closely as the nerve, limiting

222 nd ECM and (2) with or without GF with cells apposed to a known pro-motility ECM.

223 o a greater extent than LVN neurons that are apposed to a PNG.

224 The synapse is composed of an active zone apposed to a postsynaptic cluster of neurotransmitter re

225 found in the vasculature but rather closely apposed to and surrounding the outside of blood vessels,

226 l and pathological stimuli when they are not apposed to another hemichannels and face the external mi

227 the top of transmembrane (TM) 1, is closely apposed to Arg-271 at the top of TM2 in the neighboring

228 These GlyRalpha4-only clusters were apposed to bassoon immunoreactivity and hence synaptical

229 These foci were closely apposed to cis-Golgi sites marked by PfGRASP-GFP, and up

230 es hundreds of such individual release sites apposed to clusters of glutamate receptors.

231 presynaptic specializations were present and apposed to clusters of postsynaptic glutamate receptors.

232 Pericytes, which are apposed to CNS capillaries and contain contractile prote

233 nd VGLUT2 labeled varicosities were observed apposed to dDpMe-labeled axon fibers indicating both exc

234 vated lung epithelial cells that are closely apposed to deposited pathogens are ideally positioned fo

235 NG2(+) glia are closely apposed to developing cerebral vessels by being either p

236 ay, E, 12.5 to 18.5) when the RPE is closely apposed to developing RGC precursors.

237 p evaginating membranes of new discs tightly apposed to each other, which is essential for the high f

238 mentary to B1R mRNA, stringently washed, and apposed to film and emulsion.

239 active for the glycine transporter 2 or were apposed to gephyrin but did not contain the GABA-synthes

240 cdh-gammaC4 forms puncta that are frequently apposed to glutamatergic and GABAergic synapses.

241 These complexes are found apposed to glutamatergic terminals, which is indicative

242 -ir in tyrosine hydroxylase-positive neurons apposed to hcrt/orx fibers increases during copulation.

243 myocardium survives and forms grafts closely apposed to host myocardium.

244 ose regions of motor nerves and were closely apposed to ICC-IM but not smooth muscle.

245 ur when a functional presynaptic terminal is apposed to it.

246 mal, with the rough face of the sterol rings apposed to methyl-rich TM residues.

247 aled that at least half of the TH cells were apposed to microvessels at these ages, and many of these

248 f the ER is a lipid raft-like domain closely apposed to mitochondria in such a way that the 2 organel

249 les occurs at regions of ER that are closely apposed to mitochondria.

250 enlargement occurred only for those synapses apposed to motor neuron dendrites rather than to somata.

251 e dorsal brainstem and form synapses closely apposed to neurons that initiate the startle response.

252 leolinus is an RNA-rich compartment, closely apposed to or embedded within the nucleolus.

253 egion of interest is microscopic and closely apposed to other tissues regions.

254 disc-like domains of Kv2.1-IR are invariably apposed to presynaptic cholinergic C-terminals.

255 tain AMPA- and NMDA-type glutamate receptors apposed to presynaptic specializations.

256 ers and increased the proportion of clusters apposed to presynaptic terminals.

257 sion when it was on R-SNARE proteoliposomes, apposed to Q-SNARE proteoliposomes bearing PI(3)P.

258 in both control and reeler mice were closely apposed to radial glial fibers in the ventrolateral spin

259 set assumed elongated migratory morphologies apposed to radial nestin-positive fibers running through

260 eriments demonstrated that CRN terminals are apposed to retrogradely labeled reticulospinal neurons i

261 Where apposed to retroperitoneum, 2 mesothelial layers separat

262 -positive structures were frequently closely apposed to sGC-positive structures, suggesting that in t

263 uble-labeled BDA/VGAT varicosities were seen apposed to small somata labeled for glutamate consistent

264 inal and auditory nerves, respectively) were apposed to somata or were localized to dendritic segment

265 ss of supra-descemet's fluid and DM appeared apposed to stroma.

266 s) and unusual compartments (centrosomes and apposed to subdomains of the mitochondrial network).

267 ICC-DMP were closely apposed to substance P-containing nerve fibres.

268 ss common Orx varicosities were occasionally apposed to TH- or GABA-labeled dendrites without synapsi

269 different, unknown, set of vesicles, closely apposed to the cortical granules in the egg cortex.

270 stem we found TH and 5-HT reactivity closely apposed to the dendritic processes of the nucleus of the

271 since other presynaptic components are still apposed to the entire postsynaptic specialization.

272 Two interior layers of density apposed to the inner leaflet of the viral lipid bilayer

273 h VTA projecting neurons and were frequently apposed to the latter.

274 nor is it present in presynaptic structures apposed to the motoneurone.

275 a role in this process because it is tightly apposed to the node and covers the outer surface of the

276 and extend polarized lamellipodia to migrate apposed to the overlying skin.

277 btypes was intracellular, whereas 30-40% was apposed to the plasma membrane.

278 n cell bodies, with large, flat ER cisternae apposed to the PM, sometimes with a notably narrow lumen

279 whereas axotomized neurons whose axons were apposed to the PNG showed diminished expression of many

280 Apposed to the presynaptic density, this spherical or fl

281 receptors, leaving the outer plexiform layer apposed to the RPE.

282 ct regions of the cell that are more closely apposed to the substrate.

283 ll cycle, dividing cells were not so tightly apposed to the ventricular margin, and an excessive prop

284 pecifically along the path of glial end feet apposed to the vessel wall.

285 erminals change similarly to be varicosities apposed to these islands.

286 Synaptic ribbons are normally apposed to two distinct postsynaptic "dyad" partners, bu

287 ke structures formed in response to Kal7 are apposed to vesicular glutamate transporter 1-positive, b

288 arallel, Renshaw cell postsynaptic densities apposed to VGLUT1-IR synapses became smaller in adult co

289 sionally trapped at synapses where they form apposed trans-synaptic adhesive structures.

290 BDA-labeled terminals were closely apposed upon HRP retrogradely labeled somata and dendrit

291 in PeF-LH and from rRPa neurons with closely apposed, varicose orexin fibers, as well as a direct, or

292 es that both epithelial networks are closely apposed, we found that a patent luminal interconnection

293 endent manner, causes mitochondria to become apposed with a uniform gap.

294 branes (MAM), where mitochondria are closely apposed with the endoplasmic reticulum (ER).

295 These neurons are closely apposed with those of insulin-producing neurons, suggest

296 i of neighboring L2 molecules can be closely apposed within the capsid was supported using bimolecula

297 symmetric, inhibitory-type synapses or were apposed without recognized junctions.

298 immunoreactive dendrites either were closely apposed, without forming detectable synapses, or were se

299 inent eschar, and increased distance between apposing wound edges.

300 s arrest with their plasma membranes tightly apposed yet unfused.