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1 n, we present a fast heuristic algorithm for approximating energy barriers encountered during folding
2 between being able or unable to determine an approximate global fold.
3 ncipal increases in trypsin and chymotrypsin approximated to 250-fold.
4 dominant negative Rab5 (S34N) resulted in an approximate 2-fold accumulation of KCa2.3 at the plasma
5 metabolic syndrome to diabetes) conferred an approximate 2-fold adjusted risk of death (HR 2.01, 95%
6 he in vitro data allowed us to calculate the approximate cellular concentrations of the folding and d
7 ra at the temperature extremes establish the approximate chemical shifts for folded and unfolded form
14 ent of Met(8) and Leu(12) by Ala resulted in approximate 20- and 55-fold decreases of inhibitor poten
15 rolysis of these same substrates, wherein an approximate 10(5)-fold difference in rates was measured,
17 e chain reaction of cerebellar mRNA, were an approximate 10-fold down-regulation of pituitary tumour-
18 unken cells exhibit DNA fragmentation and an approximate 4-fold elevation of caspase-3-like activity.
19 most potent of these congeners possessed an approximate 5-fold enhancement of the activity of colchi
20 P-transgenic reporter strain demonstrated an approximate 20-fold enrichment of ILK-competent cells, s
23 molecular weight RNA binds histones with an approximate 100-fold greater affinity relative to DNA wh
24 ver, hexon-modified Ad5 vectors displayed an approximate 10-fold growth defect in complementing cells
26 usceptible apoE(-/-) background displayed an approximate 4-fold higher atherosclerotic lesion area th
27 ed ART, changes that were associated with an approximate 4-fold higher odds of recurrent malaria by d
30 fold increase in catalytic efficiency and an approximate 1,000-fold increase in the overall turnover
31 entration and hyperosmolarity resulted in an approximate 10- to 15-fold increase in penetration of HT
33 y joined via a flexible linker, there was an approximate 18-20-fold increase in the affinity of the p
34 lavage fluid (BALF) analysis demonstrated an approximate 18-fold increase in Muc5ac protein, which fo
35 utions; it was a loss of efficiency, with an approximate 2- to 5-fold increase in the cost of doing s
37 ration assay documents that CT-1 provokes an approximate 2-fold increase in embryonic cardiac myocyte
39 Cognate CD4(+) T cell help results in an approximate 2-fold increase in the frequency of secondar
42 293 cells with Stim1 and Orai1 results in an approximate 20-fold increase in store-operated Ca(2+) en
44 .88; 95% CI, 1.30-2.75) among all men and an approximate 3-fold increase among African American men (
45 ports, we found that thapsigargin induced an approximate 3-fold increase in adenylyl cyclase activity
47 This hormone treatment also stimulated an approximate 3-fold increase in the phosphorylation of th
48 in VL-CDR3 and four in VH-CDR3) and gave an approximate 30-fold increase in potency in a cell-based
49 plasia or colon cancer is associated with an approximate 4- and 25-fold increase in risk, respectivel
50 s a 5' --> 3'-exoribonuclease, results in an approximate 4-fold increase in OLE1 mRNA half-life in th
51 inding (K(i) = 0.7 +/- 0.3 microM) causes an approximate 4-fold increase in the K(m)(app) (alpha = 4.
53 ized for the highest log K(OW) POPs, with an approximate 5-fold increase in lipid equivalents concent
55 ntaining vesicle trafficking demonstrated an approximate 7-fold increase in the half-time for plasma
57 he Hct from approximately 50% to 30%, and an approximate 8- to 10-fold increase in the reticulocyte c
58 removal of doxycycline for 4 days caused an approximate 8-fold increase in the amount of OGG1 protei
59 ustering of agreement indices resulted in an approximate four-fold increase in the variance of the es
60 tids within a few hours after UV, we show an approximate three-fold increase in recombinants in the T
61 attle treated with pirlimycin resulted in an approximate two-fold increase in ecosystem respiration o
63 anxiety or depressive disorders predicted an approximate 2- to 3-fold increased risk for adulthood an
64 e unadjusted results were consistent with an approximate 2-fold increased risk for most exposure-outc
66 the Beaver Dam Offspring Study, there was an approximate 4-fold increased age-adjusted prevalence of
67 tion between hypothyroidism and HCC, with an approximate two-fold to three-fold increased risk of HCC
68 tive D/OK and D/660 antiserum found up to an approximate 10-fold loss in cross-reactivity against het
70 evealed that the optimal combination reduces approximate 28-folds of conducted doses compared with si
78 f the virus particles generated, we found an approximate 10-fold reduction in the amount of viral DNA
80 product analogues exhibited a corresponding approximate 3-5-fold reduction in cytotoxic activity [L1
82 ars to be related to the middle domain by an approximate 2-fold rotational axis, thus suggesting TcaB
84 ess, transition state theory can be a useful approximate predictor of cooperative folding speed, beca
85 ation of parotid BK channels, it produced an approximate 2-fold speeding of the channel-gating kineti
87 The two copies of the motif are related by approximate 2-fold symmetry and may form a bidentate DNA
88 alpha) subunits of each show either exact or approximate 4-fold symmetry and share a similar transmem
90 al 4 bp helix, and the overall structure has approximate two-fold symmetry, which makes it well-suite
92 single copy of PACAP increased MB incidence approximate 2.5-fold, to 66%, thereby demonstrating that
93 ry tumour-transforming gene-1 (pttg1) and an approximate 5-fold up-regulation of a structural homolog