ライフサイエンスコーパス: aquaporin

1 chieved by nature in protein channels (e.g., aquaporins).

2 ional features of biological water channels (aquaporins).

3 r increased pore size from a common ancestor aquaporin.

4 ling and osmolarity translated via different aquaporins.

5 de metabolism, cuticle proteins, opsins, and aquaporins.

6 transport properties that parallel those of aquaporins.

7 w range of plants as a full clade within the aquaporins.

8 or the involvement of water channels, called aquaporins.

9 per second) on the same magnitude as that of aquaporins.

10 Aquaporin 0 (AQP0), the major intrinsic protein of the e

11 a tetrameric alpha-helical membrane channel (Aquaporin-0) solubilized by n-Dodecyl beta-D-Maltoside a

12 vasion assays to investigate the function of Aquaporin 1 (AQP-1) signaling.

13 However, abundantly expressed aquaporin 1 (AQP1) in erythrocytes is thought not to be

14 , P-cadherin and beta-catenin) and function (aquaporin 1 and carbonic anhydrase IX).

15 oroid plexus epithelial cells indicates that aquaporin 1 and claudin-1 both remain normally polarized

16 with the overexpression of the water channel aquaporin 1, which was prevented by reactive oxygen spec

17 ls of the S3 segment of the proximal tubule, aquaporin 1-negative cells of the thin descending limb o

18 Gdf15 is normally expressed within aquaporin 1-positive cells of the S3 segment of the prox

19 of Na(+)/Pi cotransporter 2, claudin-2, and aquaporin 1.

20 I reporters based on the human water channel aquaporin 1.

21 ility, sensitivity, and specificity of urine aquaporin-1 (AQP1) and perilipin-2 (PLIN2) concentration

22 uctance but not the water flux through human Aquaporin-1 (AQP1) channels and impairs AQP1-dependent c

23 colon cancer cells and are colocalized with aquaporin-1 (AQP1) channels.

24 Aquaporin-1 (AQP1) dual water and ion channels enhance m

25 Aquaporin-1 (AQP1) enables greatly enhanced water flux a

26 Aquaporin-1 (AQP1) is a major intrinsic protein that fac

27 Water channel aquaporin-1 (AQP1) is expressed at epithelial cell plasm

28 The aquaporin-1 (AQP1) water channel is a potentially import

29 sed a prototype adenoviral vector to express aquaporin-1 (AQP1), presumably in the ductal cell layer

30 proximal tubule is mediated predominantly by aquaporin-1 (AQP1).

31 The adenoviral gene transfer of human aquaporin-1 (hAQP1) water channels to the liver of 17alp

32 LIM-FRET) and identified interaction between aquaporin-1 and band 3 at a distance of 8 nm, within the

33 Adaptable interaction between aquaporin-1 and band 3 reveals a potential role of water

34 sporting capacity, which lags behind that of aquaporin-1 by 3 orders of magnitude.

35 onic anhydrase enzymes and the water channel Aquaporin-1 for targeting this subpopulation of platelet

36 imilarity between the pf values of SGLT1 and aquaporin-1 makes a transcellular pathway plausible, it

37 Furthermore, water permeation through aquaporin-1 mediates the EV deformability, which further

38 In particular, aquaporin-1 upregulation occurred in acquired resistance

39 synthase, but the expression of endothelial aquaporin-1 water channels was unaltered.

40 express proximal tubular markers megalin and aquaporin-1.

41 Total aquaporin 2 (AQP2) and phospho-S256-AQP2 (pAQP2) protein

42 in, and the diagnosis of CN revealed loss of aquaporin 2 (AQP2) expression in collecting ducts in pat

43 ctive, alternative strategies for modulating aquaporin 2 (AQP2) trafficking have been sought.

44 ency led to a reduction in the percentage of aquaporin 2 (Aqp2)(+) principal cells (PCs) in the colle

45 This effect decreased the abundance of aquaporin 2 and enhanced its intracellular retention, su

46 tubular cells with ET but not PA, and urine aquaporin 2 levels were higher with ET (5.52 +/- 1.06 ng

47 T5 transcription factors, which regulate the aquaporin 2 promoter.

48 Upon immunohistochemistry, aquaporin 2 was concentrated along the apical membrane o

49 s and prevented AVP-induced translocation of aquaporin 2, further suggesting the effects in SHR-A3 re

50 g the collecting duct-specific water channel aquaporin 2, whereas autoantibodies of the two other pat

51 C-like cells selectively integrated into the aquaporin 2-positive medullary collecting duct when micr

52 d mCCDcl1 cells, and DHHC 3 was expressed in aquaporin 2-positive principal cells of mouse aldosteron

53 We observed PON-2 expression in aquaporin 2-positive principal cells of the distal nephr

54 , including the AVP-regulated water channel, aquaporin 2.

55 Pod:CR) and a tubular marker (Urinary pellet aquaporin 2:creatinine ratio) were measured in macro-alb

56 th phosphorylated forms of the water channel aquaporin-2 (AQP2) and modulate its function.

57 interaction between the renal water channel aquaporin-2 (AQP2) and the lysosomal trafficking regulat

58 promotes redistribution of the water channel aquaporin-2 (AQP2) from intracellular vesicles into the

59 kidney, and immunolocalized its protein and aquaporin-2 (AQP2) in CD principal cells.

60 Aquaporin-2 (AQP2) is crucial for water homeostasis, and

61 Aquaporin-2 (AQP2) is essential for water homeostasis.

62 water permeability through regulation of the aquaporin-2 (AQP2) water channel. This action is widely

63 luminal fluid of the nephron occurs through aquaporin-2 (AQP2) water pores in principal cells that l

64 in abundance by vasopressin; interacts with aquaporin-2 (AQP2), Hsp70, and Hsc70; and can directly u

65 idiuresis and increased urine osmolality and aquaporin-2 abundance.

66 binds to the cytoplasmic PDZ-ligand motif of aquaporin-2 and accelerates its endocytosis in the absen

67 the interaction, in association with reduced aquaporin-2 endocytosis and prolonged plasma membrane aq

68 ase in water retention, urine osmolality and aquaporin-2 expression and phosphorylation.

69 utant kidneys showed increased expression of aquaporin-2 mRNA but mislocalized expression of aquapori

70 Vasopressin-induced aquaporin-2 phosphorylation within the type I PDZ-ligand

71 aporin-2 mRNA but mislocalized expression of aquaporin-2 protein in the cytoplasm of CD cells.

72 Signaling events coupling PKA activation and aquaporin-2 regulation were largely unknown until the ad

73 nary concentrating ability, with a preserved aquaporin-2 response to desmopressin and an intact respo

74 -2 endocytosis and prolonged plasma membrane aquaporin-2 retention.

75 attenuated lithium-induced downregulation of aquaporin-2 through a mechanism different from that of a

76 echanisms that regulate the abundance of the aquaporin-2 water channel in renal collecting duct cells

77 despite normal effects on the transcellular aquaporin-2-dependent pathway.

78 eraction involving the water channel protein aquaporin-2.

79 cells to regulate the water channel protein aquaporin-2.

80 Tagging N-terminal fragments of TMC1 with Aquaporin 3 (AQP3) and GFP fusion reporter, which intrin

81 Aquaporin 3 (AQP3) is a transporter of water, glycerol a

82 Aquaporin 3 (AQP3), a water/glycerol channel protein, ha

83 and ERKs 1/2, and decreased Src kinases and aquaporins 3 and 4.

84 Aquaporin-3 (AQP3) has an important physiological functi

85 Aquaporin-3 (AQP3) is a small transmembrane water/glycer

86 Aquaporin-3 (AQP3) is a water and glycerol channel expre

87 ds on entry into the cell by transit through aquaporin-3 (AQP3), a plasma membrane H2O2-conducting ch

88 Aquaporin-3 deficiency slows cyst enlargement in experim

89 Aquaporin 4 (AQ4) is not expressed in the choroid plexus

90 cooperation between the glial water channel aquaporin 4 (AQP4) and the transient receptor potential

91 The glymphatic system, that is aquaporin 4 (AQP4) facilitated exchange of CSF with inte

92 neuritis (ON), the presence of antibodies to aquaporin 4 (AQP4) has diagnostic and prognostic value.

93 staining showed aberrant co-localization of aquaporin 4 (AQP4) in retracted GFAP+ astrocytes with di

94 Aquaporin 4 (AQP4) is highly expressed at perivascular g

95 Aquaporin 4 (AQP4) is highly expressed in the glial cell

96 Water channel aquaporin 4 (AQP4) plays a key role in the regulation of

97 ostasis.SIGNIFICANCE STATEMENT Water channel aquaporin 4 (AQP4) plays a key role in the regulation of

98 Moreover, mRNA expression of water channel, aquaporin 4 (AQP4) was increased after Dp71 deletion.

99 receptor potential isoform 4 (TRPV4) and the aquaporin 4 (AQP4) water channel in retinal Muller cells

100 by pathogenetic serum IgG autoantibodies to aquaporin 4 (AQP4), the most abundant water-channel prot

101 unity control cohort, autoantibodies against aquaporin 4 and high-titer Abs against myelin oligodendr

102 ic neuritis and myelitis and the presence of aquaporin 4 antibodies (AQP4-abs).

103 Testing for aquaporin 4 antibodies was undertaken in all suspected c

104 may indicate stem cell-capabilities whereas aquaporin 4 has been reported to promote the osmorecepto

105 tive glia whereas GFAP and the water-channel aquaporin 4 were found at the periphery.

106 chloride cotransporter-1, 2.8-fold increase; aquaporin 4, 8.9-fold increase (3.6-fold increase in chr

107 ce Ags (myelin oligodendrocyte glycoprotein, aquaporin 4, acetylcholine receptor, and muscle-specific

108 n molecules are excluded from the GJ plaque (Aquaporin 4, EAAT2b), while others are quite penetrant (

109 s, an IgG autoantibody binding to astrocytic aquaporin 4, the principal water channel of the central

110 METHOD: (1) Retrospective cohort of 76 aquaporin 4-antibody (AQP4-Ab)-positive patients from Ox

111 (1) Retrospective cohort of 76 aquaporin 4-antibody (AQP4-Ab)-positive patients from Ox

112 Thirty-nine patients with aquaporin 4-IgG seropositive NMOSD (age: 50.1+/-14.1 yea

113 ight junction protein zonula occludens 1 and aquaporin 4.

114 ina revealed that an increased expression of aquaporin-4 (AQP-4) in the flight mice compared to contr

115 with reduced reactive gliosis and polarized aquaporin-4 (AQP4) distribution.

116 oimmune disease caused by antibodies against aquaporin-4 (AQP4) expressed on astrocytes.

117 Perivascular localization of aquaporin-4 (AQP4) facilitates the clearance of intersti

118 The glial water channel protein aquaporin-4 (AQP4) forms heterotetramers in the plasma m

119 The water channel aquaporin-4 (AQP4) forms supramolecular clusters whose s

120 d peptides in multiple sclerosis (MS) and to aquaporin-4 (AQP4) in neuromyelitis optica spectrum diso

121 The organization of aquaporin-4 (AQP4) into large plasma membrane assemblies

122 The water channel protein aquaporin-4 (AQP4) is expressed in astrocytes and mediat

123 ort system is supported by the water channel aquaporin-4 (AQP4) localized to vascular endfeet of astr

124 Using an aquaporin-4 (AQP4) M1-isoform-specific enzyme-linked imm

125 r recruitment of the water-permeable channel aquaporin-4 (AQP4) to astrocytic endfeet is dependent on

126 biogenesis, hydrophilic peptide loops of the aquaporin-4 (AQP4) water channel are delivered to cytoso

127 toimmune CNS disorder mediated by pathogenic aquaporin-4 (AQP4) water channel autoantibodies (AQP4-Ig

128 colleagues show that the two isoforms of the aquaporin-4 (AQP4) water channel may determine the fate

129 Aquaporin-4 (AQP4) water channel-specific IgG distinguis

130 earance mechanism additionally suggests that aquaporin-4 (AQP4) water channels facilitate convective

131 s optica-immunoglobulin G (NMO-IgG) binds to aquaporin-4 (AQP4) water channels in the central nervous

132 ous studies have reported an upregulation of aquaporin-4 (AQP4), a water channel protein, following b

133 MO patients carry IgG autoantibodies against aquaporin-4 (AQP4), an astrocytic water channel.

134 e-specific major water channel in the brain, aquaporin-4 (AQP4), in brain plasticity and learning.

135 Aquaporin-4 (AQP4), the primary water channel in glial c

136 e discovery of serum antibodies (Ab) against aquaporin-4 (AQP4), which unequivocally differentiate NM

137 ed by ELISA in patients with NMOSD (n=39, 28 aquaporin-4 (AQP4)-Ab-seropositive, 3 double-Ab-seronega

138 ord MRIs for ring-enhancing lesions from 284 aquaporin-4 (AQP4)-IgG seropositive patients at Mayo Cli

139 le serum on live cell-based assays (CBA) for aquaporin-4 (AQP4)-M23-IgG and myelin-oligodendrocyte gl

140 Aquaporin-4 (AQP4)-specific T cells are expanded in neur

141 trogliosis, and mislocalization of astrocyte aquaporin-4 (AQP4).

142 er fluxes augmented by vasopressin-regulated aquaporin-4 (AQP4).

143 known to modulate edema formation, including aquaporin-4 and AMP-activated protein kinase and its dow

144 raightforward when the highly specific serum aquaporin-4 antibodies are detected with cell-based assa

145 come, and prognostic features in relation to Aquaporin-4 antibody (AQP4-Ab) status, and compared to a

146 The patient population included a ratio of aquaporin-4 antibody seropositive and seronegative patie

147 al, we enrolled adults aged 18-74 years with aquaporin-4 antibody seropositive or seronegative NMOSD

148 O according to Wingerchuk's 2006 criteria or aquaporin-4 antibody-positive NMO spectrum disorder (NMO

149 is activated and, IP(3) R, TRPA1, TRPV4, and Aquaporin-4 are all involved in shaping the dynamics of

150 d maintained expression of the water channel aquaporin-4 at astrocytic perivascular endfeet of the BB

151 At a molecular level, aquaporin-4 expression decreased and the expression and

152 ysed using cell-based assays for MOG-IgG and aquaporin-4 immunoglobulin G (AQP4-IgG).

153 uded 1047 patients, of whom 915 (87.4%) were aquaporin-4 immunoglobulin seropositive.

154 t of cerebral edema; 2) perivascular pool of aquaporin-4 plays a critical role in water egress from b

155 yn) that demonstrate diminished perivascular aquaporin-4 pool but retain the non-endfoot and ependyma

156 od-brain barrier disruption via perivascular aquaporin-4 pool.

157 Total aquaporin-4 protein expression was not different between

158 content, blood-brain barrier disruption, and aquaporin-4 protein expression were determined at 24 hou

159 ould focus on areas of unmet need, including aquaporin-4 seronegative disease, and on development of

160 ting pathogenic autoantibodies targeting the aquaporin-4 water channel (AQP4).

161 patients have serum antibodies targeting the aquaporin-4 water channel expressed on the end-feet of a

162 Pathogenic antibodies targeting the aquaporin-4 water channel on astrocytes are associated w

163 totic, express glutamate receptors, and form aquaporin-4(+) perivascular endfeet.

164 tic and expressed increased levels of water (aquaporin-4) and ion (Kir4.1) channels.

165 synthetase, glutamate transporter 1 (GLT1), aquaporin-4, aldehyde dehydrogenase 1 family member L1,

166 hich recognize the immunodominant epitope of aquaporin-4, exhibit Th17 polarization and cross-react w

167 Less frequent were aquaporin-4, voltage-gated Kv1 potassium channel-complex

168 dren with ADEM, seizures, encephalitis, anti-aquaporin-4-antibody (AQP4-Ab)-seronegative neuromyeliti

169 n both N-methyl-D-aspartate receptor-IgG and aquaporin-4-IgG coexisted (71%).

170 ence (on December 31, 2011) of NMO/NMOSD and aquaporin-4-IgG seroincidence and seroprevalence (sera c

171 idemiological studies are limited by lack of aquaporin-4-IgG seroprevalence assessment, absence of po

172 Aquaporin-4-IgG was measured by M1-isoform-fluorescent-a

173 ng diseases (IDD) with a specific biomarker, aquaporin-4-IgG.

174 All NMOSD patients were positive for aquaporin-4-immunoglobulin G, and all sarcoidosis cases

175 ting its effect via the perivascular pool of aquaporin-4.

176 cellular volume by means of ion channels and aquaporin-4.

177 of hyper-osmotic stress on two transporters, aquaporin 5 (AQP5) and the transient receptor potential

178 salivary gland hypofunction, we developed an aquaporin 5 (AQP5) Cre mouse line to produce genetic rec

179 st, expression of TMEM16A, the water channel aquaporin 5 (AQP5), and other regulators of sweat gland

180 secretion accompanied by down-regulation of aquaporin 5 and an increase in anti-M3R autoantibodies.

181 mma markedly improved salivary secretion and aquaporin 5 expression in anti-PD-L1-treated NOD/ShiLtJ

182 The present work revealed that aquaporin 5 expression, a water channel critical for sal

183 carinic Acetylcholine receptor M3) and AQP5 (Aquaporin 5) protein expression, b) decreased saliva sec

184 Aquaporin-5 (AQP5) plays a role in breast cancer cell mi

185 r epithelial type I (AT1) cell-specific gene aquaporin-5 (Aqp5).

186 FGF2 up-regulates aquaporin-5 and the expression of the alpha3 and alpha6

187 cinar differentiation markers in vivo (e.g., aquaporin-5 and transmembrane protein 16).

188 lls express the pro-acinar markers SOX10 and aquaporin-5.

189 ts stained positive for glycerol transporter aquaporin 7 and phosphorylated perilipin-1 following adr

190 The gene hub Aquaporin-7 (Aqp7), a water and glycerol channel, was id

191 Aquaporin-7 is identified as a critical regulator of nut

192 7 induces expression of the glycerol channel aquaporin 9 (AQP9) in virus-specific memory CD8+ T cells

193 r purification, while concurrently retaining aquaporins' ability to conduct highly selective superfas

194 aCl) triggered a rapid repression of overall aquaporin activity in both genotypes.

195 rt during salt stress conditions to modulate aquaporin activity, thereby significantly altering the p

196 The small intestine is void of aquaporins adept at facilitating vectorial water transpo

197 of the PLASMA MEMBRANE INTRINSIC PROTEIN2;1 aquaporin and its removal from the plasma membrane.

198 pmental mechanisms such as stomata aperture, aquaporin and lateral root positioning.

199 In transmembrane proteins like the aquaporin and M2 channels, the presence of histidine res

200 id profiles, and decreased the expression of aquaporins and amino acid transporters (L-type amino aci

201 Intracellular transport is facilitated by aquaporins and H(2) O(2) is removed by catalase, peroxir

202 aperone-like genes or the down-regulation of aquaporins and metal transmembrane transporters that was

203 ng porins and beta-barrel protein nanopores, aquaporins and related polar solute pores, and a number

204 Diffusivity was unaffected by blockers of aquaporins and Rh complex (Hg(2+), p-chloromercuribenzoi

205 P0 has a lower water permeability than other aquaporins and the evolution of our present understandin

206 Pyramidal neurons do not express aquaporins and thus display low inherent water permeabil

207 aulic conductivity driven by deactivation of aquaporins, and downstream limitation of ion leakage thr

208 Aquaporin (Aqp) 11 was also potently down-regulated, whe

209 report the results of a multicentre study of aquaporin (AQP) 4 antibody (AQP4-Ab) assays in neuromyel

210 GABA(A)Rs colocalize with the water channel aquaporin (AQP) 4 in prominin-1 immunopositive (P(+)) pr

211 The aquaporin (AQP) family of integral membrane protein chan

212 The function of aquaporin (AQP) protein in transporting water is crucial

213 tatic field emanating from the center of the aquaporin (AQP) water and solute channel is responsible

214 e regulation might include interactions with aquaporin (AQP) water channel isoforms, although the pro

215 Aquaporin (AQP) water channels facilitate water transpor

216 was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla.

217 Previous studies reported aquaporin (AQP)-3 expression in cysts derived from colle

218 Aquaporin- (AQP) 3, a water and glycerol channel, plays

219 Mutations in the Trypanosoma brucei aquaporin AQP2 are associated with resistance to pentami

220 Aquaporins (AQPs) are a ubiquitous family of transmembra

221 Aquaporins (AQPs) are biological water channels known fo

222 Aquaporins (AQPs) are integral membrane proteins whose f

223 Aquaporins (AQPs) are water channel proteins that are es

224 Aquaporins (AQPs) are water channels allowing fast and p

225 Aquaporins (AQPs) are water channels that mediate a vari

226 very high level in the fly renal tissue: the aquaporins (AQPs) Drip and Prip and the aquaglyceroporin

227 Aquaporins (AQPs) in the major intrinsic family of prote

228 also involve the expression and function of Aquaporins (AQPs), a family of membrane channel proteins

229 Compared to other aquaporins (AQPs), lens-specific AQP0 is a poor water ch

230 , driven by the membrane potential, although aquaporins are normally strictly impermeable for ionic s

231 Specific ion channels/aquaporins are over-expressed in metastatic cells and pl

232 Aquaporins are water channel proteins that mediate the f

233 her membrane-bound compartments, for example aquaporins, are suggested to trigger a CO(2) -sensing re

234 milarity of water and NH3 has pointed to the aquaporins as putative NH3-permeable pores.

235 ipts associated with stress avoidance (e.g., aquaporins), as well as those involved in the prevention

236 stress by affecting the transcript levels of aquaporins, as well as CYP79B2, an enzyme involved in au

237 erted actions of solute carrier channels and aquaporins at various positions along the nephron and in

238 development of therapeutic agents targeting aquaporin channel activity.

239 of 248 lens proteins, including Crystallin, Aquaporin, Collagen and enzymes that catalyze glycolysis

240 transport across membranes is facilitated by aquaporins, denoted as peroxiporins.

241 cell-generated H(2)O(2) enters the cell via aquaporins, depletes glutathione and thus abrogates the

242 Aquaporins differentially regulate cell-cell adhesion in

243 ROS-scavenging system, Heat Shock Proteins, aquaporins, expansins, and desiccation related proteins

244 r mixed populations comprising as few as 10% aquaporin-expressing cells are sufficient to produce MRI

245 ), comparable to that of other cells lacking aquaporin expression.

246 We progress through its joining the aquaporin family as a water channel in its own right and

247 The aquaporin family of integral membrane proteins is compos

248 annels were developed with an aim to replace aquaporins for possible uses in water purification, whil

249 Accordingly, a range of aquaporins from mammals, plants, fungi, and protozoans d

250 n of plasma membrane intrinsic protein (PIP) aquaporins from the plasma membrane (PM) to intracellula

251 the identification and characterization of a aquaporin gene, MusaPIP2;6 which is involved in salt str

252 7 and SlPIP2;5, were identified as candidate aquaporins genes because of highly expressed in tomato r

253 volume, the role of membrane water channels (aquaporins) has remained hypothetical.

254 asma membrane Intrinsic Protein 2;1 (PIP2;1) aquaporin have a defect in stomatal closure, specificall

255 protein PIP2;5 is the most highly expressed aquaporin in maize (Zea mays) roots.

256 TEIN 2;1 (AtPIP2;1), a major plasma membrane aquaporin in rosettes, shows circadian oscillations and

257 uction, selectivity, and proton exclusion by aquaporins in general.

258 ta and emphasizes the central role played by aquaporins in regulating plant water relations.

259 effect on intercellular water trafficking by aquaporins in stem xylem during soil drying and recovery

260 a polarized distribution of Na+/H+ pumps and aquaporins in the cell membrane, which creates a net inf

261 hodeficient and phosphomimetic forms of this aquaporin indicated that AtPIP2;1 phosphorylation is nec

262 OsPIP1;3 and OsPIP2;6 lines was inhibited by aquaporin inhibitors, silver nitrate and sodium azide.

263 simultaneous transcriptional repression and aquaporin internalization to modify root cell water cond

264 t the individual and integrated functions of aquaporins involved in drought response remains unclear.

265 Regulation of aquaporins is a key process of living organisms to count

266 expression of the main root plasma membrane aquaporins is associated with the increase of root hydra

267 Low aquaporin levels or mixed populations comprising as few

268 The aquaporin ligand bumetanide derivative AqB011 was the mo

269 fferent phylogenetic groups adopt the unique aquaporin-like hourglass helical fold.

270 the narrowest opening in naturally occurring aquaporins measuring approximately 3 A across, and hence

271 H(2)O(2) enters cells through aquaporin membrane proteins and covalently modifies cyto

272 At the whole organ level aquaporins modify water conductance and gradients at key

273 ions between specific SNARE proteins and PIP aquaporins modulate their post-Golgi trafficking and thu

274 ds for pharmaceutic development of selective aquaporin modulators.

275 , boric acid, and H2O2 Thus, we propose that aquaporins NIP4;1 and NIP4;2 are exclusive components of

276 Aqy1, which is a water transporting aquaporin of the yeast Pichia pastoris, is suggested to

277 rized NIP4;1 and NIP4;2, two pollen-specific aquaporins of Arabidopsis thaliana.

278 We show that aquaporin overexpression produces contrast in diffusion-

279 Moreover, these new insights in aquaporin permeation may allow the pharmacological explo

280 racting partners uncovered a plasma membrane aquaporin, PIP2;7.

281 the particular case of plant plasma membrane aquaporins (PIPs), PIP1 and PIP2 monomers interact to fo

282 Taken together, this study concludes that aquaporins (SlPIP2;1, SlPIP2;7 and SlPIP2;5) contribute

283 localization of lipid and water molecules in aquaporin systems, the binding of cholesterol to the G p

284 The aquaglyceroporins are a subfamily of aquaporins that conduct both water and glycerol.

285 Nature has protein channels (e.g., aquaporins) that preferentially transport water molecule

286 ion to information on cellular regulation of aquaporins, this study provides novel and complementary

287 The circadian fluctuations in aquaporin transcript abundance suggest that aquaporin wa

288 plit-opened collecting ducts or decreases in aquaporin water channel type 2 levels.

289 gulation of membrane transporters, including aquaporin water channels and sugar transporters, and myc

290 Inhibition of aquaporin water channels by mercuric chloride eliminates

291 aquaporin transcript abundance suggest that aquaporin water channels play a role in these processes.

292 second per molecule, which is comparable to aquaporin water channels.

293 elated dynamics of molecules passing through Aquaporin water transport complexes located within the i

294 ervous system (CNS) and on the regulation of aquaporins while LXRalpha has its most marked effects on

295 id bilayers and membrane proteins, including aquaporins, with an emphasis on simulation studies that

296 transporters encoded by Slc14a2, as well as aquaporins within the inner and outer medulla.

297 hanism for intracellular sequestration of PM aquaporins without further degradation.

298 possible post-translational modification of aquaporin Z (AqpZ), and surpasses previous reports of se

299 gh water permeability, which is about 50% of aquaporin Z's capacity, makes channel 1 the fastest amon

300 We begin with the history of aquaporin zero (AQP0), the most prevalent membrane prote