ライフサイエンスコーパス: aquaporin 1

1 or H7, and blocked by HgCl2, an inhibitor of aquaporin 1.

2 I reporters based on the human water channel aquaporin 1.

3 of Na(+)/Pi cotransporter 2, claudin-2, and aquaporin 1.

4 nown structures of the KcsA K(+) channel and aquaporin 1.

5 orter and the proximal tubule water channel, aquaporin-1.

6 express proximal tubular markers megalin and aquaporin-1.

7 of water-only transport pathways mediated by aquaporin-1.

8 igation of the water-permeation mechanism of aquaporin-1.

9 ormed on the structures of the water channel aquaporin-1.

10 it affect the distribution or expression of aquaporins 1, 3, or 4.

11 e was no decrease in the renal expression of aquaporins 1, 3, or 4.

12 helial cell adhesion molecule 1 (PECAM), and aquaporin 1, a marker of vasculogenesis.

13 Aquaporin 1, a six-transmembrane domain protein, is a wa

14 identified and characterized the A. gambiae aquaporin 1 (AgAQP1) protein that is homologous to AQPs

15 otein (GFAP) promoter driving the EGFP-AQP1 (Aquaporin-1, an MRI reporter) fusion gene were employed.

16 on related genes Rock1 and Rock2, as well as aquaporin 1 and beta2 adrenergic receptor in female mice

17 y which the knockdown of Rock1 and Rock2, or aquaporin 1 and beta2 adrenergic receptor in female mice

18 , P-cadherin and beta-catenin) and function (aquaporin 1 and carbonic anhydrase IX).

19 oroid plexus epithelial cells indicates that aquaporin 1 and claudin-1 both remain normally polarized

20 c resolution crystal structures of mammalian aquaporin 1 and the bacterial glycerol permease GlpF.

21 Different aquaporin-1 and aquaporin-3 inhibitors proved to have no

22 LIM-FRET) and identified interaction between aquaporin-1 and band 3 at a distance of 8 nm, within the

23 Adaptable interaction between aquaporin-1 and band 3 reveals a potential role of water

24 Aquaporin-1 and Na/H exchanger-3 deficiency enhances TGF

25 GFR difference was found to be augmented in aquaporin-1 and Na/H exchanger-3 knockout mice, suggesti

26 In contrast, the expression levels of aquaporin-1 and the all subunit of the Na-K-ATPase were

27 Aquaporin-1 and versican were downregulated in the HCM,

28 orins 3 and 8 in primitive erythroblasts and aquaporins 1 and 9 in adult definitive erythroblasts.

29 hich in large part occurs via a gas channel (aquaporin 1) and acidifies the cell.

30 alpha-helical transmembrane domains (opsin, aquaporin 1, and a connexin) with their area obtained fr

31 e to those through the transmembrane protein aquaporin-1, and are practically independent of the leng

32 vasion assays to investigate the function of Aquaporin 1 (AQP-1) signaling.

33 Aquaporin-1 (AQP-1), the universal water channel, is res

34 xpression of 2 angiogenesis-related markers, aquaporin 1 (AQP1) and cellular retinoic acid-binding pr

35 The water channel aquaporin 1 (AQP1) and certain Rh-family members are per

36 ed after the known mercury-sensitive site of aquaporin 1 (AQP1) and determined the X-ray crystal stru

37 cal and specific expression of water channel aquaporin 1 (Aqp1) and mechano-sensing genes.

38 ity map of deglycosylated, human erythrocyte aquaporin 1 (AQP1) determined at 4 A resolution in plane

39 However, abundantly expressed aquaporin 1 (AQP1) in erythrocytes is thought not to be

40 analysis and identified clear expression of aquaporin 1 (AQP1) in seven cell lines.

41 Aquaporin 1 (AQP1) is a plasma membrane water-transporti

42 rmine the roles of lipid composition and the aquaporin 1 (AQP1) water channel in altering CO2 flux ac

43 this remained unknown until discovery of the aquaporin 1 (AQP1) water channel protein.

44 Here we report the structure of the aquaporin 1 (AQP1) water channel to 2.2 A resolution.

45 Further, our results identify aquaporin 1 (AQP1), a potent effector of fluid volume re

46 Na(+)/glucose cotransporter 1 (SGLT1) and of aquaporin 1 (Aqp1), a water channel, at the attachment s

47 cell SGLT1, a Na+/glucose cotransporter, and aquaporin 1 (AQP1), a water channel, to the attachment s

48 gulated by secretin-responsive relocation of aquaporin 1 (AQP1), a water-selective channel protein, f

49 Dex-treated rats had increased abundance of aquaporin 1 (AQP1), AQP3, and Na-K-2Cl co-transporter pr

50 n studies that OEG express the water channel aquaporin 1 (AQP1), both in vivo and in vitro.

51 Additionally, the water channel protein aquaporin 1 (AQP1), expressed at high levels in erythroc

52 ons of CBCECs with an antibody against human aquaporin 1 (AQP1).

53 uggested that this is not the case for human aquaporin 1 (AQP1).

54 Expression of aquaporin-1 (AQP1) and -2 (AQP2) channels in the kidney

55 e retinal pigment epithelium (RPE) expresses aquaporin-1 (AQP1) and components of the natriuretic pep

56 ility, sensitivity, and specificity of urine aquaporin-1 (AQP1) and perilipin-2 (PLIN2) concentration

57 uctance but not the water flux through human Aquaporin-1 (AQP1) channels and impairs AQP1-dependent c

58 colon cancer cells and are colocalized with aquaporin-1 (AQP1) channels.

59 Aquaporin-1 (AQP1) dual water and ion channels enhance m

60 Aquaporin-1 (AQP1) enables greatly enhanced water flux a

61 Aquaporin-1 (AQP1) expression is induced by hypertonicit

62 Aquaporin-1 (AQP1) facilitates the osmotic transport of

63 w the convergent evidence demonstrating that aquaporin-1 (AQP1) facilitates water transport across en

64 er channel activity, several studies suggest Aquaporin-1 (AQP1) functions as a nonselective monovalen

65 cytes and liposomes containing water channel aquaporin-1 (AQP1) have suggested that AQP1 is able to t

66 The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia and aquap

67 The mammalian lung expresses water channel aquaporin-1 (AQP1) in microvascular endothelia, AQP4 in

68 Aquaporin-1 (AQP1) is a major intrinsic protein that fac

69 Aquaporin-1 (AQP1) is a member of a family of integral m

70 Aquaporin-1 (AQP1) is a member of the membrane intrinsic

71 Aquaporin-1 (AQP1) is a water channel expressed by chola

72 Aquaporin-1 (AQP1) is a water channel expressed strongly

73 Aquaporin-1 (AQP1) is a water channel protein expressed

74 Aquaporin-1 (AQP1) is a water channel that is induced by

75 Aquaporin-1 (AQP1) is a water channel, overexpressed in

76 Aquaporin-1 (AQP1) is an integral membrane protein that

77 Prevention of cation permeation in wild-type aquaporin-1 (AQP1) is believed to be associated with the

78 Water channel aquaporin-1 (AQP1) is expressed at epithelial cell plasm

79 Water channel aquaporin-1 (AQP1) is expressed in erythrocytes and vari

80 nce is presented here that the water channel aquaporin-1 (AQP1) is present in the ZG membrane and par

81 Water channel aquaporin-1 (AQP1) is strongly expressed in kidney in pr

82 Aquaporin-1 (AQP1) is the principal water-transporting p

83 Aquaporin-1 (AQP1) is the prototype integral membrane pr

84 igid body docking of the atomic model of the aquaporin-1 (AQP1) tetramer showed that the freeze-fract

85 The aquaporin-1 (AQP1) water channel is a potentially import

86 For example, in Xenopus oocytes, the aquaporin-1 (AQP1) water channel is cotranslationally di

87 Aquaporin-1 (AQP1) water channel protein expression is i

88 Aquaporin-1 (AQP1) water channels are expressed in the p

89 Aquaporin-1 (AQP1) water channels are expressed widely i

90 To investigate the role of aquaporin-1 (AQP1) water channels in proximal tubule fun

91 known blockers of water permeability through aquaporin-1 (AQP1) water channels were mercurial reagent

92 ich were proposed to consist of tetramers of aquaporin-1 (AQP1) water channels.

93 The aquaporin-1 (AQP1) water transport protein contains a po

94 ected with cRNA encoding either human or rat aquaporin-1 (AQP1) were used as controls.

95 orrelating with tumor growth inhibition, and Aquaporin-1 (AQP1), a water channel modulated in tumor c

96 sed a prototype adenoviral vector to express aquaporin-1 (AQP1), presumably in the ductal cell layer

97 The UT-B inhibitors did not reduce aquaporin-1 (AQP1)-facilitated water transport.

98 gy (Ea = 3.7 kcal/mol), similar to mammalian aquaporin-1 (AQP1).

99 transport water mainly via the water channel aquaporin-1 (AQP1).

100 lity in the absence of protein channels like aquaporin-1 (AQP1).

101 proximal tubule is mediated predominantly by aquaporin-1 (AQP1).

102 tion has been observed for several including aquaporin-1 (AQP1).

103 T-B and the major erythrocyte water channel, aquaporin-1 (AQP1).

104 ncluding cytokeratin 19, integrin beta4, and aquaporin-1, but not a hepatocyte marker, albumin.

105 sporting capacity, which lags behind that of aquaporin-1 by 3 orders of magnitude.

106 efficacy of serotype 5, adenoviral-mediated aquaporin-1 cDNA transfer to a single previously irradia

107 The cationic permeability of the aquaporin 1 channel is activated by a cyclic adenosine m

108 mulations using this method are performed on aquaporin-1 channels in a lipid bilayer, resulting in a

109 In Xenopus oocytes injected with aquaporin 1 complementary RNA, the application of forsko

110 wo groups was observed in cells labeled with aquaporin 1, cytokeratin 7, and a-smooth muscle actin.

111 wo groups was observed in cells labeled with aquaporin 1, cytokeratin 7, and alpha-smooth muscle acti

112 d with altered tumor vasculature produced by aquaporin-1 deletion.

113 Expression of aquaporin-1 did not alter P(CO2) (and thus the limiting

114 Molecular dynamics simulations of aquaporin-1 embedded in a solvated lipid bilayer were ca

115 administration was traced to a reduction in aquaporin-1 expression in the kidney of LXRbeta(-/-) mic

116 mal polarization of alkaline phosphatase and aquaporin-1 for 7 mo, without teratoma formation.

117 onic anhydrase enzymes and the water channel Aquaporin-1 for targeting this subpopulation of platelet

118 activity until Agre and colleagues purified aquaporin-1 from human erythrocytes and reported its cDN

119 the osmotic-permeability regulation of human aquaporin 1 (hAQP1) expressed in Xenopus oocyte membrane

120 The adenoviral gene transfer of human aquaporin-1 (hAQP1) water channels to the liver of 17alp

121 cient, recombinant adenovirus encoding human aquaporin-1 (hAQP1), the archetypal water channel, was c

122 tissue in diseased rats was vascularized by aquaporin-1(+) high endothelial venules and vascular cel

123 They proved that aquaporin-1 is a specific water channel by cRNA expressi

124 data indicate that the carboxyl terminus of aquaporin-1 is intracellular and that loops C and E are

125 imilarity between the pf values of SGLT1 and aquaporin-1 makes a transcellular pathway plausible, it

126 ermined pd value, we conclude that pf/pd for aquaporin-1 measures approximately 12.

127 Aquaporin-1 mediates proximal tubule fluid reabsorption,

128 Furthermore, water permeation through aquaporin-1 mediates the EV deformability, which further

129 The water-selective pathway through the aquaporin-1 membrane channel has been visualized by fitt

130 MUTM-NEI/1 cells expressed mRNA for NCAM, aquaporin 1, myocilin/trabecular meshwork glucocorticoid

131 ls of the S3 segment of the proximal tubule, aquaporin 1-negative cells of the thin descending limb o

132 could dictate a lower level of expression of aquaporin-1 on the mature red cell surface.

133 Moreover, human RBCs devoid of either aquaporin-1 or aquaporin-3 were equally permeable to H(2

134 Gdf15 is normally expressed within aquaporin 1-positive cells of the S3 segment of the prox

135 id-reconstituted two-dimensional crystals of aquaporin-1 preserved in vitrified buffer in the absence

136 Aquaporin-1 protein abundance was not significantly decr

137 in the exosomal sorting of the water channel aquaporin-1 represents a newly described mechanism by wh

138 cular volume, which is associated with lower aquaporin 1 that is important for cerebrospinal fluid se

139 on, RGS4 expression inhibited trafficking of aquaporin 1 to the plasma membrane in LLC-PK1 cells and

140 together with recent studies that show that aquaporin 1 transports both CO2 and O2.

141 Finally, a high level of aquaporin 1 unexpectedly appeared at the apical surfaces

142 In particular, aquaporin-1 upregulation occurred in acquired resistance

143 serted at sequential sites within TM2 of the aquaporin-1 water channel by in vitro translation of tru

144 induces the exocytic insertion of functional aquaporin-1 water channels (AQP1) into the apical membra

145 synthase, but the expression of endothelial aquaporin-1 water channels was unaltered.

146 t analysis showed approximately 1.4 x 10(12) aquaporin-1 water channels/cm2 of capillary surface, whi

147 with the overexpression of the water channel aquaporin 1, which was prevented by reactive oxygen spec