コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 d in reliably high ESBA105 concentrations in aqueous humor.
2 of impedance of nutritional support from the aqueous humor.
3 ll infiltration and protein concentration in aqueous humor.
4 s log colony-forming units per milliliter of aqueous humor.
5 on of transforming growth factor-beta in the aqueous humor.
6 body are critical for the production of the aqueous humor.
7 both mutated and wild-type myocilin into the aqueous humor.
8 -specific polymerase chain reaction (PCR) in aqueous humor.
9 aration at the concentration levels found in aqueous humor.
10 ow that mutant MYOC is not secreted into the aqueous humor.
11 nalyze myocilin complex formation in porcine aqueous humor.
12 which clearly distinguished POAG from normal aqueous humor.
13 a2 levels are elevated in glaucomatous human aqueous humor.
14 (DMEM) or DMEM supplemented with 50% porcine aqueous humor.
15 ents, but only after incubation with porcine aqueous humor.
16 ed by reduced pressure-dependent drainage of aqueous humor.
17 flat cells that separate the cornea from the aqueous humor.
18 when novobiocin (0.1 mM) was present in the aqueous humor.
19 , urine (64 days), amniotic fluid (38 days), aqueous humor (101 days), cerebrospinal fluid (9 months)
20 able Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 week
21 ly if myocilin was preincubated with porcine aqueous humor (78% +/- 77% when preincubated in DMEM con
22 generation of regulatory T cells (Tregs) by aqueous humor (AH) and identified TGF-beta as a critical
23 beta 2 (TGFbeta(2)) is often elevated in the aqueous humor (AH) and trabecular meshwork (TM) of patie
25 trophozoites can enter the AC; however, the aqueous humor (AH) contains factors that either induce e
26 lar pressure (IOP) resulting from diminished aqueous humor (AH) drainage through the trabecular pathw
28 rmed by enzyme-linked immunosorbent assay in aqueous humor (AH) obtained from human donor eyes (POAG
30 ribution of MRP4 in human TM (HTM) cells and aqueous humor (AH) outflow pathway was determined by RT-
31 intraocular pressure (IOP) due to increased aqueous humor (AH) outflow resistance, which is associat
32 tension arising from increased resistance to aqueous humor (AH) outflow through the trabecular meshwo
34 P results from the resistance to drainage of aqueous humor (AH) produced by the ciliary body in a pro
37 of all uveitis patients, positive for RV in aqueous humor analysis (polymerase chain reaction [PCR]
38 ed interleukin (IL)-6 and IL-8 levels in the aqueous humor and a concomitant approximately twofold (P
39 ting the secretion of mutant myocilin in the aqueous humor and by decreasing intracellular accumulati
40 Best2 appears to antagonize the formation of aqueous humor and cause an inhibition of both F(c) and F
41 els of TNF-alpha, CCL-2/MCP-1, and ICAM-1 in aqueous humor and CCL-2/MCP-1 and ICAM-1 levels in retin
42 iary body and choroid plexus, the sources of aqueous humor and cerebrospinal fluid, respectively.
43 ommunicate via soluble agents present in the aqueous humor and implicate Best2 as a critical mediator
44 In addition, Gremlin was present in human aqueous humor and in the perfusate medium of perfusion-c
45 AG) based on elevated levels in glaucomatous aqueous humor and its ability to induce extracellular ma
46 ntercellular adhesion molecule-1 (ICAM-1) in aqueous humor and retina and nuclear translocation of nu
48 ociation between levels of IL-6 and MMP-2 in aqueous humor and the axial lengths of the eye globes (I
49 active form (hDE-117) was maintained in the aqueous humor and the target tissue (iris-ciliary body)
50 that regulate pressure-dependent drainage of aqueous humor and thus intraocular pressure (IOP) are un
52 egment, and comparing myocilin levels in the aqueous humor and trabecular meshwork of Tg-MYOC(Y437H)
55 Further, a single dose of DPT-GFX sustained aqueous humor and vitreous humor drug levels during the
56 ctive oxygen species (ROS) production in the aqueous humor, and caused greater CE cell loss, includin
57 lenses are capable of protecting the cornea, aqueous humor, and crystalline lens of rabbits from UV-i
58 he ocular anterior segment of human eyes and aqueous humor antioxidant levels of ascorbate (AsA) and
61 U, we characterized the metabolic profile of aqueous humor (AqH) of patients with HLA-B27-associated
62 tic lymphocytes were found to be absent from aqueous humor (AqH) of virtually all patients with recen
63 ere killed when the disease was at its peak; aqueous humor (AqH) was collected from one eye, and the
64 s after LPS injection, eyes were enucleated, aqueous humor (AqH) was collected, and the number of inf
69 mammals in which secretion and absorption of aqueous humor are circumferential around and through the
70 iliary body and the activity of MMP-2 in the aqueous humor are increased whereas tissue inhibitor of
71 is a vasoactive peptide that is elevated in aqueous humor as well as circulation of primary open ang
73 after injection of killed bacteria into the aqueous humor at any time point; however, injection of S
76 Mutant myocilin was not secreted into the aqueous humor but accumulated in the ER of the trabecula
79 sustained therapeutic drug concentrations in aqueous humor can be achieved for long-term (i.e., 28 da
80 much better efficacy with significantly less aqueous humor cells and lower vitreous opacity scores (p
81 regions, oxygen levels were decreased in the aqueous humor closest to the pars plicata of the ciliary
85 l growth factor (VEGF) concentrations in the aqueous humor decreased (P = 0.0003), whereas the concen
86 omes after treatment with IFN-gamma, porcine aqueous humor, dexamethasone, or a calcium ionophore in
88 re grown in DMEM supplemented with 50% human aqueous humor (DMEM-AH), heat-denatured DMEM-AH, 10% fet
90 odeling of ECM is crucial to maintain normal aqueous humor drainage and intraocular pressure (IOP).
92 sure as the result of abnormal resistance to aqueous humor drainage is a major contributing, and the
93 d intraocular pressure (IOP) due to impaired aqueous humor drainage is a major risk factor for the de
94 of the anterior chamber angle containing the aqueous humor drainage tissue in situ were imaged by TPE
95 is characterized by increased resistance to aqueous humor drainage, elevated IOP, optic nerve degene
101 arding the effects of glaucoma medication on aqueous humor dynamics and the impact of this on intraoc
102 igates the correlation between parameters of aqueous humor dynamics and the influence of CCT in healt
106 macologic agents or genetic manipulations on aqueous humor dynamics in mice and other animal models.
108 ure of the tissues and cells specialized for aqueous humor dynamics in zebrafish show conservation wi
113 from their glaucoma medication before their aqueous humor dynamics study measurements at baseline an
114 comprehensive ophthalmic examination before aqueous humor dynamics study measurements, including flu
117 on the molecular and cellular mechanisms of aqueous humor dynamics using this species, the authors h
120 with NO's having a mechanoregulatory role in aqueous humor dynamics, with eNOS induction at elevated
121 itric oxide (NO) increases the rate at which aqueous humor exits the eye; however, the involvement of
122 cantly during the nocturnal period, although aqueous humor flow decreases by 50% or more at night.
130 c outflow facility (C) and fluorophotometric aqueous humor flow rates (F) were measured in nine norma
131 is study evaluated the effect of timolol, an aqueous humor flow suppressant, on outflow facility in h
132 d in the regulation of outflow resistance of aqueous humor flow through the trabecular meshwork (TM).
133 This phenomenon may be related to reduced aqueous humor flow, but the precise mechanism remains to
134 These observations support the posit that aqueous humor flow, which is a factor that contributes t
135 trabecular meshwork (TM) cells might detect aqueous humor fluid shear stress via interaction of the
136 of the eye, particularly in the drainage of aqueous humor fluid, which are believed to bring about c
140 in understanding the mechanisms controlling aqueous humor formation and thereby intraocular pressure
145 ar meshwork (TM) tissue controls drainage of aqueous humor from the anterior chamber of the eye prima
146 ns to maintain fluid homeostasis by draining aqueous humor from the eye into the systemic circulation
147 structure in the eye that functions to drain aqueous humor from the intraocular chamber into systemic
148 to quantify the effect of dynamic motion of aqueous humor from the posterior to the anterior chamber
153 athology in the primary drainage pathway for aqueous humor in the eye is responsible for ocular hyper
160 rming growth factor-beta2 (TGF-beta2) in the aqueous humor is the main cause of fibrosis of TM in POA
161 drug concentrations in intraocular tissues (aqueous humor, lens, and iris) versus eyes not receiving
162 Patients with AMD had significantly higher aqueous humor levels of cadmium (median: 0.70 micromol/L
163 No significant differences were observed in aqueous humor levels of manganese and selenium between p
164 ation of MMC to the endothelium and into the aqueous humor may lead surgeons to reassess appropriate
166 an unclassified uveitis, 7 of whom underwent aqueous humor (n = 5) or vitreous humor (n = 2) analysis
167 liary body and level of IL-18 protein in the aqueous humor of DBA/2J mice are dramatically increased
168 ytokines of the innate immune system, in the aqueous humor of patients undergoing repeat DMEK for gra
169 r testing 16 clinical samples collected from aqueous humor of patients undergoing therapeutic anterio
170 d compare the cytokine concentrations in the aqueous humor of patients with acute nonarteritic anteri
171 sure alterations of trace elements levels in aqueous humor of patients with non-exsudative (dry) AMD.
173 os with free metalloproteinases (MMP) in the aqueous humor of patients with primary open angle glauco
174 lloprotease family that are increased in the aqueous humor of POAG arising from a variety of conditio
175 of 6-carboxyfluorescein elimination from the aqueous humor of the perfused eye was reduced 80% when n
177 f SC has been proposed to underlie increased aqueous humor outflow (AHO) resistance, which leads to e
178 is characterized by increased resistance to aqueous humor outflow and a stiffer human trabecular mes
179 leton disruptor that decreases resistance to aqueous humor outflow and decreases intraocular pressure
180 on of the eye, plays a key role in promoting aqueous humor outflow and maintenance of normal intraocu
181 ligands that offer the potential to improve aqueous humor outflow and protect RGCs simultaneously, a
182 cides with a reduction in available area for aqueous humor outflow and the confinement of outflow to
184 or 96 hours caused a significant increase in aqueous humor outflow facility (110%) compared with cont
185 way, blocked both PEA-induced enhancement of aqueous humor outflow facility and PEA-induced phosphory
186 ate that the administration of AEA increases aqueous humor outflow facility and that this effect of A
187 as used to measure the effects of statins on aqueous humor outflow facility in the anterior segments
189 dding 3, 30, or 300 nM of noladin ether, the aqueous humor outflow facility increased concentration d
193 is study was to investigate the variation of aqueous humor outflow facility with body position change
194 ed to significantly reduced IOP and improved aqueous humor outflow facility, which was sustained for
204 was efficacious in both, increasing ex vivo aqueous humor outflow in porcine eyes and inhibiting myo
205 lar pressure (IOP) caused by a resistance to aqueous humor outflow in the trabecular meshwork (TM).
206 important regulator of TEK signaling in the aqueous humor outflow pathway and identify a new therape
207 hat selective inhibition of myosin II in the aqueous humor outflow pathway leads to increased aqueous
208 tructure or alterations in morphology of the aqueous humor outflow pathway were observed after treatm
209 fy druggable targets within the conventional aqueous humor outflow pathway, which is thought to be re
211 and organization is required to maintain the aqueous humor outflow resistance and intraocular pressur
212 ontribute to the homeostatic modification of aqueous humor outflow resistance are also upregulated or
213 he trabecular meshwork (TM) provides most of aqueous humor outflow resistance in the eye, an in vitro
214 assess versican's potential contributions to aqueous humor outflow resistance, its segmental distribu
215 se, they make homeostatic corrections in the aqueous humor outflow resistance, partially by increasin
217 ity of the TM tissue and consequently impede aqueous humor outflow resulting in elevated intraocular
218 In PCG, defects in the anterior chamber aqueous humor outflow structures of the eye result in el
220 and is caused by developmental defects in 2 aqueous humor outflow structures, Schlemm's canal (SC) a
221 laucoma surgeries reduce IOP by facilitating aqueous humor outflow through a vent fashioned from the
222 Our results demonstrate that PEA increases aqueous humor outflow through the TM pathway and these e
223 ular pressure due to increased resistance of aqueous humor outflow through the trabecular meshwork (T
224 traocular pressure (IOP) due to insufficient aqueous humor outflow through the trabecular meshwork an
225 a degradable inner core designed to modulate aqueous humor outflow to provide immediate IOP reduction
228 ins in the aqueous outflow pathway increases aqueous humor outflow, possibly through altered cell adh
235 ll volume changes and changes in the rate of aqueous humor outflow; agents that decrease trabecular m
236 al (SC) cells may also provide resistance to aqueous humor outflow; therefore, this study tests the i
240 (EVP), conventional outflow facility (C(t)), aqueous humor production (F(a)), and anterior chamber vo
241 m of the mouse eye results in a reduction in aqueous humor production and complete loss of the vitreo
242 is consistent with a major role of alpha2 in aqueous humor production and suggests that, potentially,
244 wever, the effect of medications that reduce aqueous humor production on outflow facility in living h
245 normal monkeys appeared to have no effect on aqueous humor production or tonographic outflow facility
248 n, as there was no significant difference in aqueous humor protein concentration between treated and
255 ry cytokines, and correlate levels with IOP, aqueous humor samples were analyzed from 23 eyes with op
259 urther by determining the phosphorylation of aqueous humor sCD44 in normal and primary open-angle gla
261 gh two mechanisms: CA inhibition to decrease aqueous humor secretion (reduce inflow) and NO release t
262 the ocular anterior segment responsible for aqueous humor secretion and absorption have been well ch
263 were used to identify and study the sites of aqueous humor secretion and absorption in adult zebrafis
264 IOP is controlled by the balance between aqueous humor secretion from the ciliary body (CB) and i
266 d by cell culture from blood, saliva, urine, aqueous humor, semen, and breast milk from infected or c
267 (0.1 mM) or novobiocin (0.1 mM) added to the aqueous humor side of the tissue, or MK571 (5-(3-(2-(7-c
268 in reaction detected parasite DNA in 8/60 OT aqueous humor specimens but failed to identify Type II s
273 freezing, IL-1beta released by PMNs into the aqueous humor stimulates FGF-2 synthesis in corneal endo
274 oid, a calcium ionophore, and a component of aqueous humor, suggesting that TM cells respond to envir
276 yocilin appears to form a complex in porcine aqueous humor that enables it to bind specifically withi
277 ncrease was diminished in cells treated with aqueous humor that was first passed through a 3-kDa or a
279 chnique was developed to measure the flow of aqueous humor through the uveoscleral pathway in porcine
280 e mammalian eye is responsible for secreting aqueous humor to maintain intraocular pressure, which is
281 dy in the Ussing chambers was greater in the aqueous humor-to-blood direction than in the blood-to-aq
284 and uveoscleral outflow (F(u)), and rate of aqueous humor turnover, were calculated from measured da
287 when preincubated in DMEM containing porcine aqueous humor versus 13% +/- 15% when preincubated with
288 freezing, and IL-1beta concentration in the aqueous humor was elevated in a time-dependent manner af
289 TUNEL and caspase-3 ELISA; ascorbate in the aqueous humor was evaluated by nuclear magnetic resonanc
292 ocilin in the iridocorneal angle tissues and aqueous humor was studied by immunohistochemistry and We
294 (2)) and myeloperoxidase (MPO) activities of aqueous humor were determined up to 25 hours postinfecti
300 uilibrium between production and drainage of aqueous humor, with compromised drainage generally viewe