ライフサイエンスコーパス: arabinogalactan

1 ylation analysis and (13)C NMR) as a type II-arabinogalactan.

2 galactofuranosyl-containing polysaccharide, arabinogalactan.

3 zyme required for the synthesis of cell wall arabinogalactan.

4 h control the link between peptidoglycan and arabinogalactan.

5 te production and abrogating mycolylation of arabinogalactan.

6 possibly by oligosaccharides such as type II arabinogalactan.

7 t the D-arabinan or D-galactan components of arabinogalactan.

8 hydrolyzes arabinoxylan but not arabinan or arabinogalactan.

9 alpha-1,5-arabinans, beta-1,4-galactans, and arabinogalactans.

10 t AGP motif was assumed to be substituted by arabinogalactans.

11 amounts of corynomycolate were esterified to arabinogalactan, a large amount of cardiolipin was prese

12 The arabinogalactan (AE-AG) was composed mainly of Ara (41%)

13 mycolic acids connected to peptidoglycan via arabinogalactan (AG) and abbreviated as the mAGP complex

14 synthesis of arabinans of both the cell wall arabinogalactan (AG) and lipoarabinomannan (LAM) of Myco

15 and immunological polymers in the context of arabinogalactan (AG) and lipoarabinomannan (LAM) respect

16 mycobacterial cell wall, forming the unique arabinogalactan (AG) and lipoarabinomannan (LAM), respec

17 Central to this envelope are arabinogalactan (AG) and lipoarabinomannan (LAM), two co

18 cinyl groups to the arabinan domains of both arabinogalactan (AG) and lipoarabinomannan (LAM).

19 eria possess a unique complex cell wall with arabinogalactan (AG) as a critical component.

20 d with a plastocyanin-like (PCNL) domain, an arabinogalactan (AG) glycomodule, and a predicted glycos

21 Proteins decorated with arabinogalactan (AG) have important roles in cell wall s

22 Arabinogalactan (AG) isolated from dust of a traditional

23 In keeping with this difference, more arabinogalactan (AG) molecules, linking the mycolic acid

24 The arabinogalactan (AG) of slow growing pathogenic Mycobact

25 ronan linked to the rhamnosyl residue in the arabinogalactan (AG) of the AGP and with arabinoxylan at

26 Classical arabinogalactan (AG) proteins (13), AG peptides (9), fas

27 harides (PHWSP) were identified as a type II arabinogalactan (AG), with characteristic terminally lin

28 harides (PHWSP) were identified as a type II arabinogalactan (AG), with characteristic terminally lin

29 d glycopolymers, lipoarabinomannan (LAM) and arabinogalactan (AG).

30 oglycan (PG) via a connecting polysaccharide arabinogalactan (AG).

31 d absence of isolated mannoproteins (MP) and arabinogalactans (AG) from WPM.

32 y enzymes that cleave the D-arabinan core of arabinogalactan, an unusual component of the cell wall o

33 e transfer of mycolic acids to the cell wall arabinogalactan and 2) through the synthesis of trehalos

34 s an additional polysaccharide layer made of arabinogalactan and an outer membrane layer composed pre

35 equence of a gum arabic HRGP, contained both arabinogalactan and arabinooligosaccharide addition site

36 ssembly of the nonreducing terminal motif of arabinogalactan and EmbC is involved in transferring ara

37 e D-arabinan-containing cell wall components arabinogalactan and lipoarabinomannan, suggesting they a

38 ns are all fragments of two polysaccharides, arabinogalactan and lipoarabinomannan, which are found i

39 e, in part, to two lipidated polysaccharides-arabinogalactan and lipoarabinomannan.

40 key component of the mycobacterial cell wall arabinogalactan and lipoarabinomannnan.

41 cipating in the biogenesis of peptidoglycan, arabinogalactan and lipoglycans, and the cell division r

42 s are an important structural constituent of arabinogalactan and lipopolysaccharides (LPS) ubiquitous

43 phage infection as well as components of the arabinogalactan and mycolic acid synthesis pathways.

44 uberculosis (Mtb) consists of peptidoglycan, arabinogalactan and mycolic acids.

45 Overall, CEM is rich in arabinogalactan and possesses diverse biological activit

46 ytic enzymes and reduced growth on arabinan, arabinogalactan and xylan.

47 pid intermediates followed by the Pol-P-P-LU-arabinogalactan and, finally, ligation of the P-LU-arabi

48 s and linkage composition characteristics of arabinogalactans and galactomannans were recovered in al

49 icant WGCNA module, as were genes coding for arabinogalactans and proteins with GPI anchors.

50 coded cell wall proteins (e.g. extensins and arabinogalactans) and ion transporters (e.g. the high-af

51 e terminal cytosolic steps of peptidoglycan, arabinogalactan, and mycolic acid synthesis colocalize a

52 peptidoglycan, branched heteropolysaccharide arabinogalactan, and mycolic acids, is well known, and n

53 e all three major components (mycolic acids, arabinogalactan, and peptidoglycan) of the mycobacterial

54 merization of arabinose into the arabinan of arabinogalactan, and that overproduction of this Emb-sen

55 ding homogalacturonans, rhamnogalacturonans, arabinogalactans, and their modified forms.

56 )-galactan and a specialized form of type II arabinogalactan are trapped by cellulose microfibrils sp

57 peaches contained polygalacturonic acid and arabinogalactan as main polysaccharides, which were isol

58 an react non-cell-autonomously and highlight arabinogalactans as sentinels of brassinosteroid-depende

59 nstituted by rhamnogalacturonans with type I arabinogalactans as side chains, differing mainly in the

60 se and arabinose, suggesting the presence of arabinogalactans as the main polysaccharides.

61 nts of cellulose, hemicellulose, pectin, and arabinogalactans, as well as glycans unique to algae.

62 enes associated with membrane integrity e.g. arabinogalactan assembly genes cpsA/lytR/Psr, whilst for

63 /genes and an entry point for elucidation of arabinogalactan biosynthesis for AGPs.

64 For instance, ethambutol targets arabinogalactan biosynthesis through inhibition of the a

65 (DprE1), which is responsible for cell wall arabinogalactan biosynthesis.

66 mily), and its location within the "possible arabinogalactan biosynthetic gene cluster" of M. tubercu

67 lasses of plant cell wall glycans, including arabinogalactans (both protein- and polysaccharide-linke

68 he pathway for the biosynthesis of cell wall arabinogalactan, but the molecular mechanisms for drug a

69 Mycobacterium spp. consists predominately of arabinogalactan chains linked at the reducing ends to pe

70 BMS 180550 is an arabinogalactan-coated ultrasmall superparamagnetic iron

71 bulk of the galactan portion of the mycolyl-arabinogalactan complex, which is the largest component

72 possibly covalently, with the peptidoglycan-arabinogalactan complex.

73 pecifically accompanied by reduced cell wall arabinogalactan complexity but not by increased proton e

74 o block specifically the biosynthesis of the arabinogalactan component of the mycobacterial cell enve

75 This mucilage is primarily formed by arabinogalactans connected to proteins which form AGP gl

76 tionary phase, whereas LM, mycolic acid, and arabinogalactan content appeared to be unchanged.

77 sides, the cpsA mutant exhibited a decreased arabinogalactan content, indicating that CpsA plays a ro

78 e highly heterogeneous in cell walls because arabinogalactans could be absent, Hyp-O-Gal/Ara-rich mot

79 eened 14 human gut-derived Bacteroidetes for arabinogalactan-degrading activities and identified four

80 ings, as part of lipoarabinomannan (LAM) and arabinogalactan, each with markedly different structures

81 We isolated a 15-residue Hyp-arabinogalactan for structure determination by sugar ana

82 that BtGH115A is involved in degradation of arabinogalactan fragments liberated by other microbial s

83 ous studies have demonstrated that cell wall arabinogalactan from mycobacteria possesses a single gal

84 s the extraction and purification of a novel arabinogalactan from pistachio external hull.

85 ian oscillator that integrates a periplasmic arabinogalactan glycoprotein-calcium (AGP-Ca(2+) ) capac

86 Arabinogalactan glycoproteins (AGPs) are implicated in v

87 sites of galactosylation, giving rise to the arabinogalactan heteropolysaccharides that characterize

88 imary structure of the mycobacterial mycolyl arabinogalactan highlighted by three arabinan chains of

89 ns partially defined by type II O-Hyp-linked arabinogalactans (Hyp-AGs) are structural components of

90 ed-galactans, beta-1,6-linked-galactans, and arabinogalactans, in addition to earlier reported homoga

91 Arabinogalactan is a ligand for the ASGP receptor and, t

92 o)xylan and a xyloglucan, the presence of an arabinogalactan is suggested by the sugar composition of

93 thyl-glucuronic acid residues from decorated arabinogalactan isolated from acacia tree.

94 re either covalently linked to an underlying arabinogalactan layer or incorporated into trehalose gly

95 rynebacterineae cell envelope is the mycolyl-arabinogalactan (mAG) complex.

96 ated a new gene (cgp_0396) in the process of arabinogalactan modification and identified a conserved

97 y of specific xylan, xyloglucan, pectin, and arabinogalactan moieties.

98 s that can selectively probe either covalent arabinogalactan mycolates or non-covalent trehalose myco

99 An instant coffee fraction, rich in arabinogalactans, obtained by ultrafiltration, using 1 a

100 polysaccharide of streptococcal species and arabinogalactan of mycobacterial species.

101 e glycolipid trehalose monomycolate (TMM) to arabinogalactan or another molecule of TMM, yielding tre

102 oniazid known to inhibit the biosynthesis of arabinogalactan or mycolic acid, respectively.

103 ponsible for the addition of Gal residues to arabinogalactan peptide.

104 (including classical AGPs, lysine-rich AGPs, arabinogalactan peptides, fasciclin-like AGPs, plastocya

105 to its utility in phylogeny and its role in arabinogalactan peptides.

106 ining trehalose dimycolate (TDM) and mycolyl arabinogalactan peptidoglycan (mAGP), in Mycobacterium s

107 Mtb cell wall core components, mycolyl arabinogalactan peptidoglycan (mAGP), phosphatidylinosit

108 ning trehalose dimycolates (TDM) and mycolyl arabinogalactan peptidoglycan, but the exact function of

109 The "cell wall core" consisting of a mycolyl-arabinogalactan-peptidoglycan (mAGP) complex represents

110 al cell wall components, such as the mycolyl-arabinogalactan-peptidoglycan complex and lipoarabinoman

111 al cell wall components, such as the mycolyl-arabinogalactan-peptidoglycan complex and lipoarabinoman

112 The cell wall mycolyl-arabinogalactan-peptidoglycan complex is essential in my

113 all-derived lipoarabinomannan (LAM), mycolyl arabinogalactan-peptidoglycan complex, and a Triton X-11

114 macromolecular structure, termed the mycolyl-arabinogalactan-peptidoglycan complex, and the phosphati

115 omannan, the second IgM MAb bound to mycolyl-arabinogalactan-peptidoglycan complex, and the third MAb

116 l of mycobacteria, possibly with the mycolyl-arabinogalactan-peptidoglycan complex, by virtue of its

117 s structure is a glycoconjugate, the mycolyl-arabinogalactan-peptidoglycan complex, which has at its

118 that are covalently linked to the underlying arabinogalactan-peptidoglycan complex.

119 ch outer membrane covalently attached to the arabinogalactan-peptidoglycan complex.

120 mycobacterial outer membrane linkage to the arabinogalactan-peptidoglycan layer.

121 time, the proposed covalently linked mycolyl-arabinogalactan-peptidoglycan macromolecular complex was

122 g an enantiomeric specific procedure, of the arabinogalactan polymer is also presented.

123 d ligases that catalyze an attachment of the arabinogalactan polymer to peptidoglycan through the lin

124 extended our tests of the codes that direct arabinogalactan polysaccharide addition to Hyp by buildi

125 red, noncontiguous Hyp residues are sites of arabinogalactan polysaccharide attachment.

126 ontiguous Hyp in extensins do not acquire an arabinogalactan polysaccharide but are arabinosylated or

127 The resulting glycoprotein had arabinogalactan polysaccharide O-linked to all Hyp resid

128 This first complete structure of a Hyp-arabinogalactan polysaccharide shows that computer-based

129 nd clustered, non-contiguous Hyp residues as arabinogalactan polysaccharide sites.

130 and (Ser-Hyp-Hyp-Hyp-Hyp)(n) confirmed that arabinogalactan polysaccharide was added only to noncont

131 % of the Hyp residues were glycosylated with arabinogalactan polysaccharide, some remained non-glycos

132 covalent attachment to peptidoglycan via an arabinogalactan polysaccharide, they provide the basis f

133 esidues hydroxylated and substituted with an arabinogalactan polysaccharide.

134 that every Hyp residue was glycosylated with arabinogalactan polysaccharide.

135 actosylation leads to the addition of larger arabinogalactan polysaccharides (Hyp-polysaccharides).

136 d are highly glycosylated by numerous acidic arabinogalactan polysaccharides O-linked to hydroxyproli

137 yielded a population of hydroxyproline (Hyp)-arabinogalactan polysaccharides ranging in size from 13

138 at small repetitive subunits comprise larger arabinogalactan polysaccharides.

139 evealed a distinct spatiotemporal pattern of arabinogalactan protein (AGP) deposition and significant

140 isoforms of a purified Arabidopsis thaliana arabinogalactan protein (AGP) encoded by hydroxyproline-

141 have shown that a stylar transmitting tissue arabinogalactan protein (AGP) from Nicotiana tabacum (to

142 thaliana), we have identified a nonclassical arabinogalactan protein (AGP) gene, AGP31, and show that

143 Arabidopsis thaliana, consisting of a short arabinogalactan protein (AGP) motif, a His stretch, a Pr

144 e core protein of an immunoaffinity-purified arabinogalactan protein (AGP) secreted aucus carota (car

145 Here, we show that the classical arabinogalactan protein 18 (AGP18) exerts an active regu

146 ed an atypical Hyp-rich glycoprotein, AGP31 (arabinogalactan protein 31), which displays a multidomai

147 The non-enzyme wines had elevated levels of arabinogalactan protein and pectin epitopes (notably bio

148 We confirm the presence of arabinogalactan protein epitopes on root cap cell walls

149 However, the arabinogalactan protein fraction from pea attracts zoosp

150 The Hyp-AGs were isolated from two different arabinogalactan protein fusion glycoproteins expressed i

151 CELLULOSE SYNTHASE5 (CESA5) and the arabinogalactan protein SALT-OVERLY SENSITIVE5 (SOS5) ar

152 ta 120-kD glycoprotein (120K) is an abundant arabinogalactan protein that is taken up from the ECM; i

153 es from the neutral sugar side chains (e.g., arabinogalactan protein) of soluble pectic polysaccharid

154 ilage hydrocolloid was primarily composed of arabinogalactan protein-associated pectin whereas pulp h

155 h both phosphatidylinositol 3-phosphate- and arabinogalactan protein-binding domains.

156 quence for plasma membrane localization, two arabinogalactan protein-like domains, two fasciclin-like

157 In contrast, the application of the arabinogalactan-protein (AGP) binding beta-glucosyl Yari

158 glycosylphosphatidylinositol (GPI)-anchored arabinogalactan-protein (AGP) in tomato (Lycopersicon es

159 This gene encodes an arabinogalactan-protein (AGP) that is known to play a ro

160 loglucan (LM25), heteroxylan (LM11/LM27) and arabinogalactan-protein (LM2) epitopes, and sandwich-ELI

161 oteic fraction is probably represented by an arabinogalactan-protein complex that binds poorly with b

162 onstituted by four fractions, one of them an arabinogalactan-protein complex.

163 perones (Ca(2+) , Pb(2+) , polyhistidine, or arabinogalactan-protein oligopeptides).

164 Arabinogalactan-protein, for example, shows an increased

165 is wall structure, named ARABINOXYLAN PECTIN ARABINOGALACTAN PROTEIN1 (APAP1), is contrary to prevail

166 GPs, specifically of the Arabinoxylan Pectin Arabinogalactan Protein1, in limiting pathogen growth.

167 h complementary DNA (cotton PHYTOCYANIN-LIKE ARABINOGALACTAN-PROTEIN1 [GhPLA1]) that encoded the prot

168 tween p24delta5 and the GPI-anchored protein arabinogalactan protein4 (AGP4).

169 HRGPs such as arabinogalactan proteins (AGPs) and extensios play signi

170 ined whether immunostimulatory plant-derived arabinogalactan proteins (AGPs) and the honeybee-derived

171 Plant arabinogalactan proteins (AGPs) are a diverse group of c

172 Arabinogalactan proteins (AGPs) are a family of extracel

173 Arabinogalactan proteins (AGPs) are a family of highly g

174 Arabinogalactan proteins (AGPs) are abundant plant prote

175 Arabinogalactan proteins (AGPs) are complex, hyperglycos

176 s Ara or gum arabic, a commercial product of arabinogalactan proteins (AGPs) from Acacia senegal.

177 Arabinogalactan proteins (AGPs) represent a major class

178 d 120-kDa glycoprotein (120K) are two pistil arabinogalactan proteins (AGPs) that share a conserved C

179 s of biosynthetic mutants, water-extractable arabinogalactan proteins (AGPs) were isolated from the l

180 Arabinogalactan proteins (AGPs), a family of hydroxyprol

181 nanoparticles are predominantly composed of arabinogalactan proteins (AGPs), a superfamily of hydrox

182 Arabinogalactan proteins (AGPs), a superfamily of plant

183 -> 3)-d-galactans, structures found in plant arabinogalactan proteins (AGPs), is described.

184 consists of three members: hyperglycosylated arabinogalactan proteins (AGPs), moderately glycosylated

185 though plants contain substantial amounts of arabinogalactan proteins (AGPs), the enzymes responsible

186 enzymes responsible for the glycosylation of arabinogalactan proteins (AGPs).

187 Fasciclin-like arabinogalactan proteins (FLAs) are involved in numerous

188 ifferences between B. napus and pea root cap arabinogalactan proteins and (2) a cross-link between th

189 the extractability of arabinans, galactans, arabinogalactan proteins and mannans.

190 biosynthesis, localization, and function of arabinogalactan proteins and toward stimulating other st

191 This suggests that root arabinogalactan proteins are involved in the control of

192 Plasma membrane vesicles readily shed arabinogalactan proteins by an inherent mechanism that a

193 structural analysis now show that some rose arabinogalactan proteins carry a ceramide class glycosyl

194 Arabinogalactan proteins constitute a class of plant cel

195 n upex1, suggesting that primexine-localized arabinogalactan proteins could play roles in sporopollen

196 ylation of xyloglucan, N-linked glycans, and arabinogalactan proteins did not explain the aberrant wa

197 e structural similarity between some soluble arabinogalactan proteins from the cell wall space and so

198 , including pectins, xyloglucans (XyGs), and arabinogalactan proteins in isolated vesicles.

199 Our results suggest an evolutionary role for arabinogalactan proteins in the acquisition of monospory

200 Arabinogalactan proteins increased up to 8 DAG and showe

201 We find that although the arabinogalactan proteins of both species induce encystme

202 Finally, we assessed the impact of root cap arabinogalactan proteins on the behavior of zoospores of

203 s thetaiotaomicron that were up-regulated by arabinogalactan proteins or AGPs.

204 Classical arabinogalactan proteins partially defined by type II O-

205 20K, and NaPELPIII, these latter three being arabinogalactan proteins previously shown to interact di

206 organization and biogenesis (e.g., tubulins, arabinogalactan proteins) and DNA or RNA metabolism (e.g

207 coproteins, changes in the types of secreted arabinogalactan proteins, and an increase in the amounts

208 timulatory components, including apalbumins, arabinogalactan proteins, and apisimin, whose levels did

209 Commonly divided into the arabinogalactan proteins, extensins, and proline-rich pr

210 xyproline-rich glycoproteins (extensins) and arabinogalactan proteins, peroxidases, receptor-like kin

211 ll space and some plasma membrane-associated arabinogalactan proteins, thus inspiring the present inv

212 abinose and galactose, two major residues of arabinogalactan proteins.

213 of Arabidopsis cell-wall polysaccharides and arabinogalactan proteins.

214 ferase likely involved in galactosylation of arabinogalactan proteins.

215 taining pectic cell wall polysaccharides and arabinogalactan proteins.

216 O-glycan epitopes previously associated with arabinogalactan proteins.

217 The high molecular weight component in arabinogalactan-proteins (AGP/GP), and more "branched" c

218 Arabinogalactan-proteins (AGPs) are a family of hydroxy-

219 Arabinogalactan-proteins (AGPs) are cell wall proteoglyc

220 Arabinogalactan-proteins (AGPs) are extracellular proteo

221 Arabinogalactan-proteins (AGPs) are glycoproteins that i

222 Arabinogalactan-proteins (AGPs) are highly glycosylated

223 Arabinogalactan-proteins (AGPs) are hydroxyproline-rich

224 Since arabinogalactan-proteins (AGPs) are known to play a role

225 Functional analysis of the hyperglycosylated arabinogalactan-proteins (AGPs) attempts to relate biolo

226 l glycoside that interacts specifically with arabinogalactan-proteins (AGPs), a class of plant cell s

227 bidopsis (Arabidopsis thaliana), showed that arabinogalactan-proteins and arabinans represent substan

228 heteropolysaccharides that characterize the arabinogalactan-proteins.

229 Type II arabinogalactans retained by cellulose microfibrils had

230 olvent ratio, 55 degrees C, 6 h) yielding an arabinogalactan-rich polysaccharide (12.83 +/- 2.44 %) w

231 be suggested that the degradation of coffee arabinogalactan side chains can contribute to their form

232 assembly of oligosaccharides related to the arabinogalactan side chains of pectin as novel biochemic

233 Arabinose from arabinogalactan side chains was hypothesized as a possib

234 5)-L-arabinotriose, structurally related to arabinogalactan side chains, was submitted to dry therma

235 se occurring in arabinose residues of coffee arabinogalactan side chains.

236 e consensus structure for a 15-sugar residue arabinogalactan subunit with paired glucuronic carboxyls

237 cterium is not able to metabolize acacia gum arabinogalactan, suggesting that BtGH115A is involved in

238 doglycan synthesis and ethambutol to inhibit arabinogalactan synthesis underscores the ability to ide

239 However, partial definition of arabinogalactan synthesis, the site of action of several

240 se 2-oxidase (DprE1), an essential enzyme in arabinogalactan synthesis; 14 proved to be a nanomolar i

241 hile B. thetaiotaomicron grows on larch wood arabinogalactan, the bacterium is not able to metabolize

242 mycolic acids covalently linked to cell-wall arabinogalactan, thus validating the outer membrane mode

243 in vitro ligation of newly synthesized P-LU-arabinogalactan to newly synthesized peptidoglycan is a

244 ogalactan and, finally, ligation of the P-LU-arabinogalactan to peptidoglycan.

245 attachment of the cell wall polymer mycolyl-arabinogalactan to the peptidoglycan.

246 fication reactions that synthesize mycolated arabinogalactan, trehalose monomycolate (TMM), and treha

247 dependent on the presence and the branch of arabinogalactan type II (AGII) structure.

248 ned show that the heteropolysaccharide is an arabinogalactan type II, highly ramified, with lateral c

249 ing population consists of a highly branched arabinogalactan (type 2) with a molar mass of approximat

250 CMU are generally characterized as an arabinogalactan-type polysaccharide, a source of carbohy

251 hown that rhamnogalacturonan I/II, arabinan, arabinogalactan types I and II and xyloglucan from grape

252 on of epitopes associated with xyloglucan or arabinogalactan was similar in wild-type and emb30 tissu

253 Arabinan and arabinogalactan were also found in all the collected F3

254 beta-(1-->4)-Galactan and type II arabinogalactan were the main large matrix polymers reta

255 These arabinogalactans were linked to type I rhamnogalacturona

256 -B apparently contribute to the synthesis of arabinogalactan, whereas EmbC is reserved for the synthe

257 d by the chemical synthesis of a fragment of arabinogalactan, which is an important constituent of th

258 ed that these fractions are formed by pectic arabinogalactans, which contain (1-->3), (1-->6) and (1-

259 nans and hemicellulose fraction consisted of arabinogalactans, xylans and glucomannans.