ライフサイエンスコーパス: aromatic

1 All fused sapphyrins showed typical aromatic absorption features; however, the absorption fe

2 o be responsible for increasing tolerance to aromatic acids by exporting them out of the cell.

3 Mutant strains tolerant to levels of aromatic acids near the solubility limit were then analy

4 alkanoic, alkenoic, acetylenic, and (hetero)aromatic acids to the corresponding alkyl, alkenyl, alky

5 ] oxidative annulation; and lactonization of aromatic acids, anhydrides, and acrylic acid derivatives

6 haromyces cerevisiae mutants tolerant to two aromatic acids, coumaric acid and ferulic acid.

7 Besides conferring tolerance to aromatic acids, ESBP6 overexpression was also shown to s

8 ysts is promising for selective oxidation of aromatic alcohols; however, the relatively low conversio

9 (DHMA) by the monoamine oxidase TynA and the aromatic aldehyde dehydrogenase FeaB.

10 omponent reaction occurs between amino acid, aromatic aldehyde, and primary alcohol in alkaline solut

11 Here we report results of a novel aromatic aldehyde, VZHE-039, that mimics both the O(2)-d

12 s broad in scope with respect to the (hetero)aromatic aldehyde-derived aldimine and tolerates signifi

13 between thioglycosylated dipyrromethanes and aromatic aldehydes in 15-21% yields.

14 l radicals were also added to the O-atoms of aromatic aldehydes.

15 t, S385Y/D469T/R520Q, that is active towards aromatic aldehydes.

16 t together accommodate a variety of internal aromatic alkynes as substrates for cyclopropenation with

17 to clarify the formation of the heterocyclic aromatic amine (HAA) 2-amino-3,4-dimethylimidazo(4,5-f)q

18 The selected model aromatic amine, 4-(dimethylamino)benzonitrile (DMABN), w

19 Heterocyclic aromatic amines (HAAs) are neo-formed compounds generate

20 Among them, the formation of heterocyclic aromatic amines (HAAs) has been related to the declared

21 alid for the formation of other heterocyclic aromatic amines (HAAs) with the structure of quinoxaline

22 ective N-alkylation of primary and secondary aromatic amines and amides with primary, secondary, and

23 It is noteworthy that the aromatic amines are generated in situ by the reaction of

24 Aromatic amines are relevant aquatic organic contaminant

25 e of substituted amines, although the use of aromatic amines as nucleophiles requires microwave heati

26 elated with metabolites of the shikimate and aromatic amino acid biosynthesis (SA) pathways (upstream

27 naerobic respiration, nitrate metabolism and aromatic amino acid biosynthesis genes among down-regula

28 osphate synthase (DAH7PS), at the gateway to aromatic amino acid biosynthesis in Mycobacterium tuberc

29 orter can excrete fusel acids (byproducts of aromatic amino acid catabolism) and this role is shared

30 nvolved in monapterin biosynthesis(8-10) and aromatic amino acid transamination,(11) respectively, we

31 These genes encode enzymes involved in aromatic amino acid, phenylpropanoid, camalexin, and sph

32 ino acids (valine, leucine, and isoleucine), aromatic amino acids (tryptophan and phenylalanine), and

33 color parameters and fluorescence spectra of aromatic amino acids and nucleic acids (AAA + NA), trypt

34 Isolated aromatic amino acids and short peptides provide benchmar

35 hat is responsible for regulating the use of aromatic amino acids as the nitrogen source.

36 The FTIR spectra revealed the presence of aromatic amino acids derived from QF.

37 There, a tight web of aromatic amino acids grips the substrate in a sequence-p

38 en luminescence in amyloid systems devoid of aromatic amino acids have not been resolved.

39 ly complex dynamic allostery: three distinct aromatic amino acids jointly communicate occupancy to th

40 recruited to stress granules, and found that aromatic amino acids, which have previously been linked

41 ed in vivo activity, and were preferred over aromatic amino acids.

42 gher activity with IA derived from L-Glu and aromatic amino acids.

43 amined the substrate scope using substituted aromatic and aliphatic derivatives.

44 he copolymerization of highly functionalized aromatic and aliphatic monomers.

45 This protocol accommodates both aromatic and aliphatic substituents and a broad range of

46 reactions using boronic acids are applied to aromatic and allenic compounds.

47 And, aromatic and functional aspects of sour cherry vinegar w

48 road substrate scope for the N-alkylation of aromatic and heteroaromatic amines using a diverse range

49 In particular, aromatic and heteroaromatic linkers nestle within an aro

50 direct incorporation of trifluoromethyl into aromatic and heteroaromatic systems, including bioreleva

51 s in the microbiological, physical-chemical, aromatic and phenolic composition between two winemaking

52 alcoholic beverage, which is valued for its aromatic and qualitative complexity and variation.

53 o the gram scale, and a broad scope for both aromatics and halogens.

54 f Clar's analysis with respect to polycyclic aromatics and quantitatively assess the bonding and elec

55 consequent shorter lifetime of the repulsive aromatic anion of PhBr is consistent with the observatio

56 onnectivity of terminal anchor groups around aromatic anthracene cores, and by forming SAMs of the re

57 DH, especially at the first DHR, followed by aromatic antiepileptics (7/25, 28.0%), vancomycin (4/25,

58 iene (CBD) as excited-state antiaromatic and aromatic archetypes, respectively, and reveal that CBD f

59 ng the CSCJ was more prominent, according to aromatic aspect.

60 jugated) polymers that differ drastically in aromatic backbone and alkyl side chain chemistry.

61 allation of the methylamino group to (hetero)aromatic boronic acids and esters.

62 ation, etherification, and esterification of aromatic bromides showed higher yields and selectivity c

63 n transfer to the surface in the case of the aromatic, but not the aliphatic, anion.

64 Although oxidation of aromatics by these radicals has been studied for decades

65 , display high selectivity for borylation of aromatic C(sp(2))-H bonds over aliphatic C(sp(3))-H bond

66 which is capable of direct insertion into an aromatic C-H bond.

67 The iridium-catalysed borylation of aromatic C-H bonds has become the preferred method for t

68 Mutational analysis of this aromatic cage supports its role in conferring specificit

69 ified, showing divergence from the canonical aromatic-cage residues to accommodate large substrates.

70 , shedding light on the fact that monocyclic aromatics can also serve as the hitherto unrecognized pr

71 n offers a direct route to higher-order, non-aromatic carbocycles; however, the inherent issue of dic

72 lytic system for the N-alkylation of diverse aromatic carbocyclic and heterocyclic amines directly wi

73 her molecular weight DOM such as enzymes for aromatic carbon degradation, oxygenation, and decarboxyl

74 active positions for reactions of ozone with aromatic carbons in ortho-, meta-, or para-positions is

75 by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride.

76 s of pK(a) values of phenols, aliphatic, and aromatic carboxylic acids, and ketoacids.

77 ere described shows a deep pai-electron-rich aromatic cavity that exhibits a great affinity for the q

78 xperiments, indicate an unusual carbohydrate-aromatic CH-pai bonding that promotes glycopeptide self-

79 ed as a qualitative method for assessing the aromatic character of polycyclic aromatic hydrocarbons.

80 er of the condensed furoxan ring and the low aromatic character of the benzofuroxan system.

81 hat both modes of self-assembly increase the aromatic character of the squaramide synthons, giving ri

82 ir calculated NICS values, underlining their aromatic character.

83 substituents had little effect on the global aromatic characteristics.

84 NICS calculations reveal strong aromatic characters in ReB(4)(-) and ReB(4), consistent

85 adiative processes in peptides containing an aromatic chromophore requires the knowledge of the natur

86 and heteroaromatic linkers nestle within an aromatic cleft defined by F583 and F643, and different a

87 terface, strategically positioning a surface aromatic cluster of the ancillary domain as an extension

88 he aged wine spirit is a beverage with great aromatic complexity.

89 s and improves their effervescence, foam and aromatic complexity.

90 To assess the importance of pathways for aromatic compound oxidation that do not result in ring h

91 It was concluded that nitrogen-containing aromatic compounds and alkylbenzenes were oxidized by pe

92 Aromatic compounds are generally toxic for microorganism

93 a facile approach to employ two-dimensional aromatic compounds as modular building blocks to generat

94 A parameters for heterocyclic and oxygenated aromatic compounds based on historical chamber experimen

95 Emissions of aromatic compounds cause air pollution and detrimental h

96 Such systems readily obtained from simple aromatic compounds could open up a multitude of syntheti

97 Sunlight depleted the pool of aromatic compounds that supported microbial growth in th

98 ation reactions of vinyldiazo compounds with aromatic compounds using a metal-free strategy are descr

99 and some low-molecular-weight aliphatic and aromatic compounds) aggregate to form complex DOM.

100 In this work we demonstrate that aromatic compounds, dissolved in the hydrocarbon phase,

101 We find that oxygenated aromatic compounds, including phenols and methoxyphenols

102 d interactions of alkyl ureas with amide and aromatic compounds, relative to interactions with water.

103 sed levels of compounds of microbial origin (aromatic compounds, secondary or sulfated bile acids, an

104 es of unified O, N, and C atoms of amide and aromatic compounds.

105 tained in the OMVs are active and catabolize aromatic compounds.

106 often used to treat water contaminated with aromatic compounds.

107 he existence of diatropic currents in planar aromatic compounds.

108 hyl)oxazolidin-2-ones, but the corresponding aromatic congeners have been relatively underexplored.

109 A-IDPs) with different molecular weights and aromatic content, which exhibit variable condensate satu

110 n reactions to produce high molecular weight aromatic copolymers with 1,1-disubstituted alkene backbo

111 ious structural modifications at the central aromatic core are presented.

112 onjugated backbone, for example, by altering aromatic cores or by varying the length of the conjugate

113 adical cascade that connects two preexisting aromatic cores via a formal C-H activation step.

114 erties, from highly antiaromatic to strongly aromatic, could be achieved by varying the substituent.

115 nt the first structure of a Zn(II)-dependent aromatic dehalogenase that does not require a coenzyme.

116 AlPO(4) zeotype has been prepared using the aromatic diamine 1,10-phenanthroline and some of its met

117 sponding tetra-anion instead of the expected aromatic dianion.

118 sts that the presence of nitrogen-containing aromatic equatorial ligands facilitates the water nucleo

119 as applied to a broad range of aliphatic and aromatic ester precursors and to the synthesis of hetero

120 Methyl beta-d-galactopyranoside malonyl aromatic esters have been designed to target and engage

121 ecarbonylative reaction that couples (hetero)aromatic esters with a broad scope of amines to form (he

122 hat in some cases, fulvenes possessing fused aromatics exhibited a high degree of intermolecular pai-

123 rin IX (PpIX) due to the n-n stacking of the aromatic groups of SV and PpIX and strong hydrophobic in

124 nt contents in different types of spices and aromatic herbs collected from Italy and Tunisia were eva

125 ian and Tunisian samples for each spices and aromatic herbs under analysis was achieved by PCA.

126 t also of enzyme-catalyzed ring expansion of aromatic heterocycles via carbene transfer by any enzyme

127 diamine/substituted diamines and substituted aromatic/heterocyclic/aliphatic aldehydes under aerial c

128 We show that polycyclic aromatic hydrocarbon (PAH) chromophores that are linked

129 cations and evaluated for biliary polycyclic aromatic hydrocarbon (PAH) concentrations.

130 the formation of heteroatom-doped polycyclic aromatic hydrocarbon (PAH) isosteres, which expose BN mi

131 Our hypothesis is that polynuclear aromatic hydrocarbon (PAH) molecules are the dominant co

132 Aromatic hydrocarbon pool species severely hinder the di

133 chanistically, transactivation of miR-802 by aromatic hydrocarbon receptor (AHR) is inhibited by SHP.

134 igated accumulation of petrogenic polycyclic aromatic hydrocarbons (E(39)PAHs) in the livers and musc

135 routes for heteroatom-containing polycyclic aromatic hydrocarbons (H-PAHs) with alkyl and aryl subst

136 nd step economic synthesis of aza-polycyclic aromatic hydrocarbons (N-PAHs) from readily available ar

137 Among the nitrated and oxygenated polycyclic aromatic hydrocarbons (NPAHs and OPAHs) are some of the

138 Polycyclic aromatic hydrocarbons (PAHs) are a diverse group of envi

139 Polycyclic aromatic hydrocarbons (PAHs) are common atmospheric poll

140 Polycyclic aromatic hydrocarbons (PAHs) are considered to be potent

141 novel personal care products, and polycyclic aromatic hydrocarbons (PAHs) as combustion and industria

142 e associated low molecular weight polycyclic aromatic hydrocarbons (PAHs) as key mediators of cardiot

143 Specifically, polycyclic aromatic hydrocarbons (PAHs) found in ultrafine PM have

144 nthic organisms may be exposed to polycyclic aromatic hydrocarbons (PAHs) in marine sediments as the

145 late matter (PM(2.5)), species of polycyclic aromatic hydrocarbons (PAHs) including naphthalene (NAP)

146 acenes, phenacenes, and helicenes-polycyclic aromatic hydrocarbons (PAHs) that are distinct via the l

147 Polycyclic aromatic hydrocarbons (PAHs) with six and seven rings we

148 ominated diphenyl-ethers (PBDEs), polycyclic aromatic hydrocarbons (PAHs), phthalates, insecticides,

149 f non-desirable compounds such as polycyclic aromatic hydrocarbons (PAHs).

150 Zn and/or polycyclic aromatic hydrocarbons (pyrene, phenanthrene, chrysene, b

151 s the toxicity of halogenated and polycyclic aromatic hydrocarbons in vertebrates.

152 lth to determine whether prenatal polycyclic aromatic hydrocarbons interacts with DNA methylation in

153 gonal lattice of graphene-derived polycyclic aromatic hydrocarbons is a critical tool in the design o

154 oduce nanographenes, namely large polycyclic aromatic hydrocarbons that can also be regarded as atomi

155 ive for hydrogen isotope exchange at (hetero)aromatic hydrocarbons under mild conditions (50 degrees

156 ticipants include urinary hydroxy-polycyclic aromatic hydrocarbons, volatile organic chemical metabol

157 sessing the aromatic character of polycyclic aromatic hydrocarbons.

158 xtraction of seven representative polycyclic aromatic hydrocarbons.

159 mental Protection Agency-priority polycyclic aromatic hydrocarbons.

160 fore, PAH4 (sum of four different polycyclic aromatic hydrocarbons; benz[a]anthracene, chrysene, benz

161 D.IMPORTANCE In this study, we identified an aromatic hydrophobic residue in foot-and-mouth disease v

162 n addition to benzoic acid, other monocyclic aromatics (i.e., benzene, toluene, salicylic acid, benzy

163 While benzene is aromatic in its ground state, it is antiaromatic in its

164 sis for this high potency is a unique sulfur-aromatic interaction network formed by the thiourea moie

165 orms revealed increases in electrostatic and aromatic interactions between distinct secondary structu

166 mbraces, which must compete with alternative aromatic interactions of similar energy.

167 Because sulfur-aromatic interactions provide additional stabilization c

168 Sixfold phenyl embraces are well-established aromatic interactions that are strong and directional.

169 have a high contribution (~4% vs ~10%) from aromatic ions in the mass spectrum.

170 fragment should not be perceived as a simple aromatic isostere but rather as a readily interacting mo

171 plant pyridoxal 5'-phosphate (PLP)-dependent aromatic l-amino acid decarboxylase (AAAD) family has yi

172 o-associated virus serotype 2-mediated human aromatic L-amino acid decarboxylase gene therapy develop

173 ith horizontal alternating alkyl and stacked aromatic layers in both the orange and yellow forms.

174 ) in memristors based on Ru-complexes of azo-aromatic ligands.

175 left defined by F583 and F643, and different aromatic linkers direct the capping group toward shallow

176 sential oils (EOs) are natural, volatile and aromatic liquids extracted from special plants.

177 anic semiconductors, which commonly comprise aromatic moieties, may present new opportunities for the

178 ated on the phthalide core as well as on the aromatic moiety of the alkylating agent.

179 lyse the assembly of a brominated polycyclic aromatic molecule on Au(111) and demonstrate that standa

180 One manifold for the functionalization of aromatic molecules utilizes diazo compounds and a transi

181 )-pentenynes and external nucleophilicity of aromatic molecules.

182 , alcohols, ketones, aliphatic hydrocarbons, aromatics, mono-and sesquiterpenes, oxides/ethers and py

183 ts show that biomarkers within the n-alkane, aromatic, n-ketone, and alcohol fractions can be identif

184 als of different lipid fractions (n-alkanes, aromatics, n-ketones, alcohols, fatty acids and other hi

185 eteroatomic group 13 ring exhibiting a sigma-aromatic nature concomitant with a three-center two-elec

186 upgrade shell waste-derived chitin into two aromatic NCCs that currently cannot be synthesized from

187 matic upon addition of 2e(-) becomes also an aromatic nido-species, and explains the informative sche

188 A direct and selective aromatic nitration reaction may be useful in biotechnolo

189 this reaction by varying the substituents on aromatic nitriles and amino thiols and testing their rea

190 3-(dichlorophenyl)-isoxazolyl moiety or the aromatic nitrogen heterocycle with nitrogen at alpha-pos

191 A(Ty2) can initiate translation in vivo with aromatic non-canonical amino acids (ncAAs) bearing diver

192 Direct epoxidation of aromatic nuclei by cytochrome P450 monooxygenases is one

193 the solvent that leads to an intramolecular aromatic O atom insertion into the CH bond of one of the

194 Overall, using aromatic oligoamide foldamers as a chiral model, we demo

195 Molecular helices based on self-organized aromatic oligoamide foldamers have been designed and pre

196 rtant charge-transfer differences within the aromatic oligomers, depending on the helix handedness an

197 , as well as heterocoupling of aliphatic and aromatic ones.

198 particular, depending on the solvent nature-aromatic or aliphatic-cone-shaped C(3)-symmetric subphth

199 ackbone with a free carboxylate, an N-linked aromatic or heteroaromatic substituent, and a hydrophobi

200 However, most aromatic organic compounds assessed as anode materials i

201 Aromatic organic compounds can be used as electrode mate

202 me the preferred method for the synthesis of aromatic organoboron compounds.

203 The cations may react with (hetero)aromatic pai-nucleophiles in various directions, dependi

204 onserved phenylalanine residues that form an aromatic pathway whose dynamic rearrangements enable H(+

205 s templated by two constitutionally isomeric aromatic peptide amphiphiles (APAs), K(S)C'EK(S) and C'E

206 low yield of dissociation products from the aromatic PhBr was attributed to the presence of two addi

207 d functional groups to graphite edges though aromatic phenazine linkages.

208 to its three-dimensional alignment of three aromatic phenylene units, separated by two methine bridg

209 Phosphonate-directed ortho C-H borylation of aromatic phosphonates is reported.

210 for interface aliphatics, and that interface aromatics physicochemically contribute to Ail self-assem

211 tive H(2)N amination of benzylic and related aromatic picolinates under conditions mild enough to mod

212 The incorporation of aromatic plants into nests by birds is suspected to cons

213 ske oxygenases involved in bioremediation of aromatic pollutants in the environment.

214 litated by the increase of a contribution of aromatic poly(carboxylic acid)s with high conjugation le

215 es provided direct connection between simple aromatic precursors and complex small organic molecules

216 PKS, a short assembly line that generates an aromatic product.

217 o the formation of 3-hydroxyhispidin as sole aromatic product.

218 extra-framework gallium species on enriched aromatics production in zeolite ZSM-5.

219 -first" biorefinery that includes high-value aromatic products.

220 ometallic derivatives also retained strongly aromatic properties, and the proton NMR spectra showed t

221 free energies and shows that a large span of aromatic properties, from highly antiaromatic to strongl

222 1,3-dicarbonyl Ugi-4CR adducts, employing an aromatic radical cyclization process promoted by tetrabu

223 molecule by introducing substituents on the aromatic regions.

224 This interaction between an aromatic residue and quaternary amine substrates allows

225 king results also suggest that the conserved aromatic residue in the extended winged-helix domain of

226 for methyltransferase function, including an aromatic residue on alpha4 that likely forms stacking in

227 Coupled aromatic residue rotation was a graded rather than a bin

228 The valence of aromatic residues also determines full binodals that qua

229 xplore selective radical chemistry to target aromatic residues applying C-H (18)F-trifluoromethylatio

230 Ala substitutions for aromatic residues at the alphaM4-alphaM1/alphaM3 interfa

231 fferent time scales involving a repacking of aromatic residues at the interface with CI.

232 demonstrate the critical role of consecutive aromatic residues at the tip of the LBL for binding of H

233 sters, sulfone, amide, cyanide, and ketones, aromatic residues containing fluorine, chlorine, bromine

234 We show that the numbers (valence) of aromatic residues in PLDs determine the extent of temper

235 Substitution of only two stacking aromatic residues in two consecutive sugar-binding pocke

236 We also show that uniform patterning of aromatic residues is a sequence feature that promotes LL

237 Furthermore, it frequently binds to aromatic residues of OP-inhibited acetylcholinesterase (

238 BO1 by mainly contacting its three conserved aromatic residues Trp-71, Tyr-87, and Phe-89 at the cent

239 stacking interactions involving arginine and aromatic residues.

240 water-soluble organics content and saturate-aromatic-resin-asphaltene fractionation.

241 rylic acid, with mussel-inspired lysine- and aromatic-rich monomers.

242 ges, we employ a rigid planar ligand with an aromatic ring and bifunctional bond sites.

243 owing different substitution patterns on the aromatic ring and the alkene.

244 Potentially, this approach can convert any aromatic ring bearing a -CH(2) Br or a -CHO group into a

245 he chemoselective cleavage of a six-membered aromatic ring in biphenylene is reported using an alumin

246 n decalin indicate that addition of H to the aromatic ring is involved in the rate-limiting step.

247 ormation through this pathway can retain the aromatic ring of parent aromatics, shedding light on the

248 Besides COBE, two other substrates with aromatic ring structures were also used in this biphasic

249 h increasing electron donor character of the aromatic ring substituent.

250 oryl radical, reduction of the electron-poor aromatic ring to a radical anion, coupling of the radica

251 ich could potentially be replaced by a fused aromatic ring to enhance the rigidity and conjugation of

252 tramolecular addition of the alkoxide to the aromatic ring wherein charge on the aromatic system is s

253 an efficient atom-economic route to build an aromatic ring-a step ubiquitously important in organic s

254 moiety reacts with the ortho position of the aromatic ring.

255 r weight (LMW-PAH) (liver > muscle) with 2-3 aromatic ring.

256 substitution into the ortho positions of the aromatic rings allows for the rings to become coplanar;

257 luding hydrophobic pai-pai interactions with aromatic rings of side chains and hydrophilic interactio

258 Aromatic rings with high electron density are believed t

259 rial consisting of alternating aliphatic and aromatic segmented polymer strands, interwoven within di

260 For many years, Clar's aromatic sextet theory has served as a qualitative metho

261 thway can retain the aromatic ring of parent aromatics, shedding light on the fact that monocyclic ar

262 Several analogues with aromatic side arms showed improved potency (half-maximal

263 s suggest that the greater number of larger, aromatic side chains in the ENaC M2 helix may contribute

264 et of substrates with systematically growing aromatic side chains using accurate competitive linear r

265 the activity for analogs that possess larger aromatic side chains.

266 Kinetic control in the presence of six aromatic solvents has been successfully applied in the s

267 (2)N interactions with sp(2)N and with amide/aromatic sp(2)C are modestly unfavorable.

268 e loading of different methanol, alkene, and aromatic species in the cages may substantially slow dow

269 erture size 2.4 nm) concentrates over 90% of aromatic species into the porous architecture, and its a

270 linker is C(5)H(4), which indicates a ringed aromatic structure.

271 ties adopt a coplanar configuration with the aromatic SubPz core, resulting in a pai-extended chromop

272 Apart from the aromatic substituent, the benzylic leaving groups greatl

273 anisms for C-H borylation, (i) electrophilic aromatic substitution (prevalent with B-X electrophiles)

274 pment of remote regioselective electrophilic aromatic substitution (S(E)Ar) reactions that are enable

275 Nucleophilic aromatic substitution (S(N)Ar) is a classical reaction w

276 eact with biological thiols via nucleophilic aromatic substitution (S(N)Ar).

277 with a highly atroposelective electrophilic aromatic substitution catalyzed by a chiral-at-metal rho

278 The reaction rates for the nucleophilic aromatic substitution of 4,6-dichloro-5-nitrobenzofuroxa

279 echanism with the key step being a homolytic aromatic substitution of the heteroaryl halide by an ele

280 Ability of indole to undergo electrophilic aromatic substitution reaction was studied in the past w

281 lfonylpyridine products undergo nucleophilic aromatic substitution reactions with oxygen and carbon n

282 n of the E-enone (via Nazarov, electrophilic aromatic substitution, and elimination reactions) gave B

283 tion is thought to proceed via electrophilic aromatic substitution, catalyzed by enzymatic deprotonat

284 ulfones react with cysteine via nucleophilic aromatic substitution, providing a mechanistically selec

285 d by cation radical-accelerated nucleophilic aromatic substitution.

286 and morpholine (TPMA(MOR) )) by nucleophilic aromatic substitution.

287 -trig cyclization, and a final electrophilic aromatic substitution.

288 t-book mechanism of bimolecular nucleophilic aromatic substitutions (S(N)Ar) reactions is a stepwise

289 Attempted electrophilic amination of aromatics such as benzene and toluene with methyl- and t

290 the ring prevents the planar geometry of the aromatic system and induces a strong decrease in the bas

291 e to the aromatic ring wherein charge on the aromatic system is stabilized by the nearby potassium ca

292 ene 2 as a key step leading to a heptacyclic aromatic system.

293 into the reactivity of sterically congested aromatic systems and may help in designing new methods o

294 vent methanol, deuterations of electron-rich aromatic systems can be carried out under mild acid cata

295 inating, carbonyl-assisted C-H activation of aromatic systems with alpha,beta-unsaturated ketone and

296 ., cyclohexane, cyclic ethers, arenes, alkyl aromatic systems, and aldehydes/ketones, having an alpha

297 with late-stage oxidation to regenerate the aromatic terminator.

298 We show that the Baird aromatic triplet-state energy of cyclooctatetraene can b

299 The introduction of these groups around the aromatic unit is dictated by the intrinsic reactivity pr

300 clusters", in which a closo-cluster that is aromatic upon addition of 2e(-) becomes also an aromatic