コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 ed in vivo activity, and were preferred over aromatic amino acids.
2 ributed to overlapping pi-pi orbitals of key aromatic amino acids.
3 rt assays show that PhpCAT exports all three aromatic amino acids.
4 in the Acanthamoeba spp. that synthesize the aromatic amino acids.
5 spiratory nitrogen cycle and accumulation of aromatic amino acids.
6 of the Tyr9 residue with different unnatural aromatic amino acids.
7 norepinephrine and for the hydroxylation of aromatic amino acids.
8 ritical branch point in the synthesis of the aromatic amino acids.
9 B. hydrogenotrophica targets aliphatic and aromatic amino acids.
10 ands of promoters through a conserved set of aromatic amino acids.
11 binds peptides that have a high fraction of aromatic amino acids.
12 hosphate, which is required for synthesis of aromatic amino acids.
13 C domains is reliant upon widely distributed aromatic amino acids.
14 gher activity with IA derived from L-Glu and aromatic amino acids.
15 (ubiquinone biosynthesis), menaquinone, and aromatic amino acids.
16 sequence enriched in positively charged and aromatic amino acids.
17 and contained multiple large hydrophobic and aromatic amino acids.
18 attributed to overlapping pi-pi orbitals of aromatic amino acids.
19 in the visible range even in the absence of aromatic amino acids.
22 ating branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) have been shown to be associ
23 Based on recent studies, fluorophores-mainly aromatic amino acids (AAAs) in proteins-might be respons
24 ch as branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs), have been associated with d
27 lack of redox sites and the trace amounts of aromatic amino acids also eliminate the possibility that
28 ptome identified a phylogenetically distinct aromatic amino acid aminotransferase (ArAT), designated
31 n the antioxidant activity as well as on the aromatic amino acid and carotenoid contents in ordinary
32 aled differences in the microbiota-sensitive aromatic amino acid and secondary bile acid metabolism.
33 ge with particular carbon sources, including aromatic amino acids and acyclic terpenes, suggesting a
34 In conclusion, the levels of branched-chain, aromatic amino acids and alanine increased and the level
35 that Pal is a versatile surrogate to natural aromatic amino acids and can be employed as an alternati
37 in) using commercially available fluorinated aromatic amino acids and fluorinated precursors as examp
38 viously reported markers, branched-chain and aromatic amino acids and glutamine/glutamate, were assoc
39 llular bacterium that is auxotrophic for the aromatic amino acids and histidine, causes scrub typhus,
41 color parameters and fluorescence spectra of aromatic amino acids and nucleic acids (AAA + NA), trypt
42 s drawn into biosynthetic pathways that form aromatic amino acids and other important metabolites, in
43 In some cases, the PTM domain is rich in aromatic amino acids and plays an important role in memb
45 nabling rapid 1D NMR spectral acquisition on aromatic amino acids and proteins bearing aromatic resid
46 ne and glutamate, which act as precursors to aromatic amino acids and salicylic acid, respectively.
49 ectron capture mass spectra of aliphatic and aromatic amino acids and their methyl esters show intens
51 that the proteinaceous binder degrades into aromatic amino acids and/or fatty acids after exposure t
53 irst reaction of the biosynthetic pathway of aromatic amino acids, and a chorismate mutase (CM), func
54 cribe fluorinated versions of alkyl, cyclic, aromatic amino acids, and also nickel-complexes to acces
55 lasses and particle size, branched-chain and aromatic amino acids, and inflammation-related glycoprot
56 the role of a surface-accessible cluster of aromatic amino acids, and purified mutant proteins were
57 dia but do not grow in defined media lacking aromatic amino acids, and the growth defect is rescued b
58 rostatic and conformational perturbations of aromatic amino acids are associated with metal cluster a
62 ence, with a net positive charge and several aromatic amino acids, as a putative membrane-interacting
64 lectivity for N-protected dipeptides with an aromatic amino acid at the carboxylic terminus, which pr
66 aled strong evidence that branched-chain and aromatic amino acids (BCAAs and AAAs) are closely associ
67 d intracellular levels of branched-chain and aromatic amino acids (BCAAs and ARO AAs, respectively) a
68 ays for H2O2 resistance included DNA repair, aromatic amino acid biosynthesis (aroBK), Fe-S cluster b
69 elated with metabolites of the shikimate and aromatic amino acid biosynthesis (SA) pathways (upstream
70 nt set of genes coding for shikimic acid and aromatic amino acid biosynthesis enzymes, leading to the
71 naerobic respiration, nitrate metabolism and aromatic amino acid biosynthesis genes among down-regula
72 osphate synthase (DAH7PS), at the gateway to aromatic amino acid biosynthesis in Mycobacterium tuberc
73 at allows complex control of the pathway for aromatic amino acid biosynthesis in the pathogen Mycobac
74 s that B. thailandensis, when exposed to the aromatic amino acid biosynthesis inhibitor glyphosate, i
75 We also used our module to control flux into aromatic amino acid biosynthesis to increase titers of s
76 Vi capsule, lipopolysaccharide (LPS), and aromatic amino acid biosynthesis were essential for viru
78 olite in the established shikimic pathway of aromatic amino acid biosynthesis, are absent in most eur
79 M. tuberculosis provide exquisite control of aromatic amino acid biosynthesis, not only controlling f
83 ers (except C(3)) in this unusual tetrahydro-aromatic amino acid building block, giving insights into
85 orter can excrete fusel acids (byproducts of aromatic amino acid catabolism) and this role is shared
86 nits (phhA, hpd, hmgA, and dhcA) involved in aromatic amino acid catabolism; however, genes involved
88 olate high-affinity oligonucleotides against aromatic amino acids complexed in situ with a nonspecifi
90 synthesis, tryptophan hydroxylase (TPH) and aromatic amino acid decarboxylase (AADC) are expressed i
91 arginine to glutamine substitution in the L-aromatic amino acid decarboxylase (AADC) enzyme was repl
92 synthesizes dopamine through the actions of aromatic amino acid decarboxylase (AADC) in the proximal
94 mainly attributed to its decarboxylation by aromatic amino acid decarboxylase (AADC), an enzyme over
98 The cell death was reversed by caspases and aromatic amino acid decarboxylase and monoamine oxidase
100 ro-l-m-tyrosine ([(18)F]FMT; a substrate for aromatic amino acid decarboxylase), baseline D2/3 recept
101 thesis enzymes tyrosine hydroxylase (TH) and aromatic amino acid decarboxylase, providing a novel mec
104 e Catharanthus roseus and Papaver somniferum aromatic amino acid decarboxylases changes the enzymes d
106 e with phenylalanine but not other large and aromatic amino acids, demonstrating its molecular specif
107 MAGE (CoS-MAGE) to optimize biosynthesis of aromatic amino acid derivatives by combinatorially inser
109 -12-independent Th1 differentiation, whereas aromatic amino acid-derived AHR ligands were selectively
110 dy it has been shown how incorporation of an aromatic amino acid drastically improves selective antib
111 protein (IFABP) by incorporating fluorinated aromatic amino acids during synthesis in Escherichia col
112 and charging of tRNAs for branched chain and aromatic amino acids (e.g. leucine and tryptophan), the
113 res, conformation of disulphide bridges, and aromatic amino acid environment, depended on the fibres
114 y matrix of key intrinsic fluorophores, like aromatic amino acids, enzyme cofactors, and vitamins.
115 ikimate pathway leads to the biosynthesis of aromatic amino acids essential for protein biosynthesis
116 nd receptor signaling, (ii) substitutions of aromatic amino acids F295 and F296 in TM6 with alanine a
117 ith a corresponding decrease in the usage of aromatic amino acids, favoring formation of IDR structur
118 d by mutating it to other hydrophobic and/or aromatic amino acids, followed by voltage-clamp experime
119 ritical for assembly, the substitution of an aromatic amino acid for D111 produced a lethal phenotype
123 VLDL-triglycerides, VLDL-diameter, branched/aromatic amino acids, glycoprotein acetyls, and triglyce
125 rrelated with loss of pi-pi stacking between aromatic amino acids H84 and Y83, which removes a wall s
129 by which plants maintain intercompartmental aromatic amino acid homeostasis, and provide critical in
130 biopterin (BH(4)), an essential cofactor for aromatic amino acid hydrolases including tyrosine hydrox
131 ccessful knockout and complementation of the aromatic amino acid hydroxylase AAH2 gene, with no obser
132 e wild type hTPH2, like other members of the aromatic amino acid hydroxylase superfamily, exists as a
133 ) is a pterin-dependent mononuclear non-heme aromatic amino acid hydroxylase that catalyzes the conve
134 nases, namely, tetrahydrobiopterin-dependent aromatic amino acid hydroxylase, 2-oxoglutarate-dependen
135 dely distributed among eukaryotes, including aromatic amino acid hydroxylases (AAAHs), nitric oxide s
138 erall, these results are consistent with the aromatic amino acid hydroxylases all sharing the same ch
139 Additionally, expression levels of the two aromatic amino acid hydroxylases were negligible both in
144 e, Orf13 is novel in its ability to catalyze aromatic amino acid hydroxylation with hydrogen peroxide
148 erefore asserts a recognition preference for aromatic amino acids in a variety of sequence configurat
149 acking interactions between heterocycles and aromatic amino acids in biological systems, our ability
150 ore provide a rationale for the abundance of aromatic amino acids in fibril-forming peptides and esta
152 lution imaging reveals an unexpected role of aromatic amino acids in promoting protein-mHtt aggregate
153 C 7002, through site-directed mutagenesis of aromatic amino acids in the binding niche of the chlorop
162 me 10% of predicted prenylated proteins have aromatic amino acids in their Ca(1)a(2)X sequence and wo
163 The basis of the low PPII propensities of aromatic amino acids in this context was significant cis
164 and enzyme catalysis, and the involvement of aromatic amino acids in this process is of much interest
169 he change in His-heme loop stability for the aromatic amino acids is caused by a slowdown in the rate
170 ly complex dynamic allostery: three distinct aromatic amino acids jointly communicate occupancy to th
171 t enzyme that catalyzes the hydroxylation of aromatic amino acid l-phenylalanine (L-Phe) to l-tyrosin
172 der Caryophyllales, are synthesized from the aromatic amino acid l-tyrosine (Tyr) and replaced the ot
173 IE) by altering extracellular [Ca(2+)] or by aromatic amino acid, L-phenylalanine (L-Phe, endogenous
174 es successful forward engineering of complex aromatic amino acid metabolism in yeast, with the best m
178 ontains a large amount of a toxic nonprotein aromatic amino acid, mimosine, and also an enzyme, mimos
179 to binding energy are heavily biased toward aromatic amino acids near the center of the binding surf
181 us most closely related to SARS-CoV, employs aromatic amino acid-nucleobase stacking interactions wit
182 ition, but the site has moved to a different aromatic amino acid of the agonist-binding site dependin
186 etion of a 21-amino acid segment enriched in aromatic amino acids on the C-terminal side of Cys-739 a
187 lementation of infected hMDMs with the three aromatic amino acids or with Trp alone rescues the intra
189 icant stabilization of residual structure by aromatic amino acids, particularly Trp and Phe, and mini
190 suring transcriptional regulation of MAA and aromatic amino acid pathways in the filamentous cyanobac
193 d applications for cyclized analogues of the aromatic amino acids Phe, Tyr, Trp, and His within pepti
195 of COX-2 is also aided by partitioning of 4 aromatic amino acids, Phe(59), Phe(66), Tyr(76), and Phe
196 the temporal and spatial interchange of the aromatic amino acid phenylalanine (Phe) between human re
197 rimental effects of hyperaccumulation of the aromatic amino acid phenylalanine (Phe) in animals, know
200 e first steps of hydration of the protonated aromatic amino acids phenylalanine, tryptophan, and tyro
203 in stark contrast to the general belief that aromatic amino acids play a prominent role in multidrug
204 D-amino acids include N-methyl amino acids, aromatic amino acids, polar amino acids, and hydrophobic
206 initiation involves a pathway of transient, aromatic amino acid radical intermediates, including Y73
207 tic determinant of branched-chain amino acid/aromatic amino acid ratio on changes in body weight and
208 he C allele of the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 m
209 We genotyped the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 n
210 ers another level of complexity in the plant aromatic amino acid regulatory network, unveiling new ta
212 udies also revealed that viperin requires an aromatic amino acid residue at its C terminus for proper
214 revealed that the introduction of the large aromatic amino acid residue tryptophan at position 940 p
215 ns near-UV CD signals from its complement of aromatic amino acid residues (one Trp, eight Tyr, and 13
216 ia long-range radical transport (RT) through aromatic amino acid residues (Y122 left arrow over right
217 detected the partial solvent exposure of Pet aromatic amino acid residues at 37 degrees C, and a cell
218 In particular, the relative positioning of aromatic amino acid residues at positions 100 and 107 de
219 hat different cations affected structures of aromatic amino acid residues differently, which indicate
221 se mutations revealed functionally important aromatic amino acid residues in four locations: at the i
223 ing with ASLV(C) glycoproteins, at least two aromatic amino acid residues in the IgV domain of Tvc, T
224 thologues exhibited exclusive preference for aromatic amino acid residues in the P2 position, and for
225 ite-directed mutagenesis of highly conserved aromatic amino acid residues in the SPATE family resulte
226 is interface identified two highly conserved aromatic amino acid residues located in the H-I loop and
228 mine oxidases A and B (MAO A and MAO B) show aromatic amino acid residues oriented approximately perp
229 lly possess an "aromatic box," where several aromatic amino acid residues surround the bound ligand.
230 ion by UVR8 is based on intrinsic tryptophan aromatic amino acid residues, with tryptophan-285 as the
231 e present study investigates the role of the aromatic amino acid-responsive regulator PhhR in mediati
232 er, these results, along with the lack of an aromatic amino acid-rich region in CdtC similar to that
233 The juxtamembrane domain (JMD) of S is an aromatic amino acid-rich region proximal to the transmem
234 nscriptional activation of genes involved in aromatic amino acid, S-adenosyl methionine (SAM) and fol
237 1)H enrichment of a single ortho position of aromatic amino acid side chains in an otherwise perdeute
239 n protein-stabilizing interactions involving aromatic amino acid side chains make significant contrib
241 associated benzene rings (a simple model of aromatic amino acid side chains) can switch inherent dyn
242 e the strength of stacking interactions with aromatic amino acid side chains, follow predictable tren
245 elative concentrations of branched-chain and aromatic amino acids significantly increased in the free
247 roxylase catalyze the hydroxylation of their aromatic amino acid substrates using a tetrahydropterin
250 changes in Raman vibrations corresponding to aromatic amino acids such as phenylalanine and tryptopha
252 beta-sheet areas are rich in cysteine and aromatic amino acids, such as phenylalanine and tyrosine
253 gation in mutated pili that were missing key aromatic amino acids, suggest that the pili of G. sulfur
254 etes, such as branched chain amino acids and aromatic amino acids, suggesting they report on a distin
256 m tumefaciens, and two experimental systems, aromatic amino acid synthesis and DNA transfer in bacter
257 emphasized the genetics and biochemistry of aromatic amino acid synthesis and the characterization o
258 H), a shikimate pathway enzyme essential for aromatic amino acid synthesis, is also required for GA p
259 veal the existence of a fourth, more distant aromatic amino acid that serves as a terminal electron d
260 el provides insight into the organization of aromatic amino acids that are important for electrical c
261 tions were generated for the six C-terminal, aromatic amino acids that mediate most coat-internal sca
262 amino acids, exhibited impaired transport of aromatic amino acids that require a large binding site v
264 ist binding sites have the same core of five aromatic amino acids, the fetal site has approximately 3
268 mide intermediate was stabilized by adjacent aromatic amino acids through ring-ring stacking interact
269 itionally, exchange of the respective fourth aromatic amino acid to redox-inactive phenylalanines sti
270 nvolving the obligatory binding of essential aromatic amino acids to Mec1, followed by an enhancement
271 on caused by the affinity of hydrophobic and aromatic amino acids toward these surfaces leads to elec
272 nvolved in monapterin biosynthesis(8-10) and aromatic amino acid transamination,(11) respectively, we
273 e addition of aspartate and expression of an aromatic amino acid transporter, as well as a tyrosine-s
276 ino acids (valine, leucine, and isoleucine), aromatic amino acids (tryptophan and phenylalanine), and
278 en quantum yields generated by excited state aromatic amino acids (tryptophan, tyrosine, phenylalanin
280 urthermore, replacing Trp-248 with a smaller aromatic amino acid (Tyr/Phe) impaired the beta-arrestin
282 esis was used to assess the contributions of aromatic amino acids (tyrosine and phenylalanine) to rec
284 15 A distant from the chromophore by another aromatic amino acid, W389F, restores native Pr --> Pfr p
285 no-acid (aa) PTM domain of AcMNPV GP64 lacks aromatic amino acids, we asked whether this region might
286 mutase, a key enzyme in the biosynthesis of aromatic amino acids, we demonstrate the design of natur
288 show that only substitutions of Tyr(511) to aromatic amino acids were able to mimic, albeit partiall
290 stream open reading frames encoding multiple aromatic amino acids were found 5' of the translation in
291 Circulating branched-chain amino acids and aromatic amino acids were recently related to insulin re
293 ar capsules based on oligoamide sequences of aromatic amino acids which are capable of binding tartar
294 growth defect is rescued by inclusion of the aromatic amino acids, which are essential for production
295 dified Dulbecco's medium, a medium richer in aromatic amino acids, which give rise to AhR agonists, c
296 recruited to stress granules, and found that aromatic amino acids, which have previously been linked
298 cs suggest multiple stacking arrangements of aromatic amino acids with the nucleobases at the junctio
299 s work from our laboratory demonstrated that aromatic amino acids within CF lung secretions (sputum)
300 posed to involve a hopping mechanism through aromatic amino acids (Y(122) --> W(48) --> Y(356) in bet