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1 or the last step, forming the pyridine ring (aromatization).
2 via 1,2-alkyl migration and dehydrogenation (aromatization).
3 ldehydes followed by in situ cyclization and aromatization.
4 Spengler cyclization, and a radical-mediated aromatization.
5 ing dipyrromethanes and subsequent oxidative aromatization.
6 ular electrophilic aromatic substitution and aromatization.
7 owed by Lewis acid catalyzed cyclization and aromatization.
8 ding through 1,3-diene formation followed by aromatization.
9 intramolecular Michael reaction, followed by aromatization.
10 on a nitrilium ion intermediate followed by aromatization.
11 ectrocyclization in HMPA followed by in situ aromatization.
12 naphthalene precursors followed by oxidative aromatization.
13 show that Ga Lewis acid sites strongly favor aromatization.
14 ogen secretion versus placental capacity for aromatization.
15 t allylic decarboxylative rearrangement, and aromatization.
16 ainly androgen 19-desmethylation rather than aromatization.
17 enes with 2-methoxybenzoquinones followed by aromatization.
18 hways occur with substrates with no possible aromatization.
19 ver, which has led to accusations of illegal aromatization.
20 3-dipolar cycloaddition, and dehydrogenative aromatization.
21 ed through a 4 + 2 cycloaddition followed by aromatization.
22 polung of imines promoted by organocatalytic aromatization.
23 onalized aromatic ring through deoxygenative aromatization.
24 xide with an enol ether/enamide, followed by aromatization.
25 ed by a mild electrochemical decarboxylative aromatization.
26 ion, aldol condensation, and dehydrogenative aromatization.
27 ndergoes a 1,2-hydrogen shift and subsequent aromatization.
28 s-Alder (ADA) reaction, followed by a facile aromatization.
29 the key acid-promoted heterocyclization, and aromatization.
30 al mediated depropagation reaction driven by aromatization.
31 enes and benzooxanorbornadienes, followed by aromatization.
32 ion to the central allene carbon followed by aromatization.
33 condensation with concomitant debenzylative aromatization.
34 hol components, the dehydrogenations lead to aromatization.
35 Cs, which catalyze C7-C12 cyclization and/or aromatization.
36 ssential to maintain the decarboxylation and aromatization activities and avoid rapid catalyst deacti
39 n, aldol-type condensation, cyclization, and aromatization, all in the absence of coenzymes or recrui
41 l rearrangement of a diketo-dioxinone ester, aromatization and cationic diene-epoxide cyclization as
45 cyclohexadienyl radical undergoes concerted aromatization and halogen-atom or group abstraction thro
46 e the carbazole core: 6pi-electrocyclization/aromatization and indole C2-H bond activation/Heck annul
47 uent additive-free thermal treatment induced aromatization and led to exclusively para-connected, hig
50 However, studies on the mechanism of steroid aromatization and subsequent model work have provided ev
54 2 in breast tumors, as opposed to peripheral aromatization and uptake from plasma, can enhance tissue
55 polymers with varying degrees of chromophore aromatization and used them to probe the effects of synt
56 es a NIS-mediated cascade C-N bond formation/aromatization, and a series of indoles with various func
57 e activities, such as C-C bond desaturation, aromatization, and C-C bond formation, were also observe
58 attenuated astrocyte activation, astrocytic aromatization, and decreased hippocampal E2 levels compa
60 serine mutants gave mixture of dehydrations, aromatizations, and unaltered alcohol side chains depend
61 in, intramolecular C-C bond cyclization, and aromatization as the key intermediates, all occurring in
63 e (GVL) over Zn/ZSM-5 to butene, followed by aromatization at high yield with co-feeding of water.
64 corresponding estrogens, a reaction known as aromatization because it involves conversion of the delt
66 ntramolecular C-N cyclization and subsequent aromatization by the elimination of thiophenol, with goo
67 zed intramolecular Diels-Alder cycloaddition-aromatization cascade constructs the tetrasubstituted ar
68 esults in an unanticipated aza-Michael/aldol/aromatization cascade to give polysubstituted quinolines
70 ubsequent reductive cyclization/ring-opening aromatization cascade, as was found to occur with the re
71 from the known compound 9, via an unexpected aromatization caused by the addition of PhSeCl and subse
72 hand, the experimental studies revealed that aromatization competes with Michael addition mechanism i
73 Suzuki coupling, followed by dehydrogenative aromatization, completed the synthesis of calothrixin B.
77 nofunctional, (2) M/NH bifunctional, and (3) aromatization-dearomatization bifunctional molecular cat
78 cer complexes capable of bond activation via aromatization/dearomatization metal-ligand cooperation (
79 e a Lewis base or Lewis acid function, as an aromatization/dearomatization shuttle, or as an electron
84 cy for these initial cycloadducts to undergo aromatization, ene reaction, and oxidation although this
85 , because in this particular case the sum of aromatization energies no longer outweighs the buildup o
89 on additional driving force associated with aromatization, families of very powerful neutral organic
90 ation and 1,3-functional group isomerization/aromatization followed by terminal oxidation to afford 3
92 ional role of each domain in cyclization and aromatization for di-domain ARO/CYCs has remained a myst
94 s constructed via late-stage cyclization and aromatization from a diketodioxinone intermediate and ma
96 ol product was investigated and elimination, aromatization, hydrogenation, regioselective O-exchange,
97 ndazol-3-ones underwent unexpected migratory aromatization in acidic condition to produce 3-hydroxy-1
98 cting those in postmenopausal women, in situ aromatization in breast tumor makes a major contribution
99 d females, suggesting a role for presynaptic aromatization in cellular processes within these loci.
103 transfer process dominantly stabilized by an aromatization in the low-energy lying excited state.
105 istribution of aromatase suggests a role for aromatization in the regulation of pre- and postsynaptic
107 more effective than anastrazole at reducing aromatization-induced ER transactivation and proliferati
108 obese stromal cells exhibited higher maximal aromatization-induced ER transactivation and reduced ana
109 eveal that the crucial step of the oxidative-aromatization involves facile hydride transfer from the
114 rous dioxygen intermediate mediates androgen aromatization is explored and determined to be unlikely.
117 hich undergoes amination/cascade cyclization/aromatization, leading to N-arylquinazolinium salts in e
118 and 5, a second addition occurs followed by aromatization, leading to the formation of an additional
121 nerability of the CNS we reasoned that brain aromatization may protect circuits from the threats of p
124 based inhibitor of BioA that operates via an aromatization mechanism, irreversibly labeling the PLP c
126 ve and its one-pot two-step ring opening and aromatization mediated by para-toluenesulfonic acid and
128 ions are facilitated by dearomatization, and aromatization metal-ligand cooperation operates in catal
129 een TE and TREN, suggesting that neither the aromatization nor the 5alpha reduction of androgens is r
130 cyclization/[1,5]-H shift/cleavage of CS(2)/aromatization/nucleophilic acyl substitution reaction of
131 cyclization/[1,5]-H shift/cleavage of CS(2)/aromatization/nucleophilic acyl substitution reaction of
135 If the C19 aldehyde remains unhydrated, aromatization occurs with concomitant decarbonylation an
136 bisphenylphosphoryltetrahydroquinolines, the aromatization occurs with elimination of one molecule of
137 An unprecedented DDQ-mediated oxidative aromatization of 2-bezylidene-dihydrofurans yielding 2-a
138 nzyme of AHBA formation, which catalyzes the aromatization of 5-deoxy-5-amino-3-dehydroshikimic acid,
140 port a general C-C activation mode driven by aromatization of a pre-aromatic intermediate formed in s
142 tase, or cytochrome P450 19A1, catalyzes the aromatization of androgens to estrogens within the body.
144 atase (P450arom), which was confirmed by the aromatization of androstenedione (AD) to E2 and other es
145 d mRNA levels in fat and skin and whole-body aromatization of androstenedione were severely elevated.
146 eactivity patterns, involving stereospecific aromatization of bridges and nucleophile additions.
147 lyzed the cross-dehydrogenative coupling and aromatization of diarylmethyl and dialkyl benzimidazole
148 ng on structure of the starting ketones, the aromatization of intermediate dihydropyrimidines occurs
149 functional groups are obtained by oxidative aromatization of meso-tetraarylporphyrins in which pyrro
150 eforming, the dehydrocyclization and further aromatization of n-hexane are attributed to the prominen
151 al medicines and by the late-stage amination-aromatization of natural products, steroids and terpene
152 oporphyrins (Ar(4)(MeO)(8)TNP) via oxidative aromatization of nonaromatically fused porphyrin precurs
153 2-electron acceptor, catalyzes a remarkable aromatization of piperideine-2-carboxylate (P2C) to pico
154 types of porphyrins were obtained by direct aromatization of precursor porphyrins, annealed with eit
155 crease the degree of carbon condensation and aromatization of SOM functional groups, particularly on
156 erences in response to T are associated with aromatization of T to E and that reduced sensitivity to
159 ese increases were considerably greater when aromatization of testosterone to estradiol was also supp
162 e intermediate III) followed by an oxidative aromatization of the corresponding Diels-Alder adduct IV
163 henate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring by protonating
166 nium-ion mechanism in light of the fact that aromatization of the dihydro intermediates (formed via a
168 convergent dibromocyclopropanation and total aromatization of the furobenzocycloalkane are also repor
169 g point instead to electrocyclic closure and aromatization of the heptamethine chain in Cy7 forming F
171 uct the dihydronaphthalene unit of 2 and the aromatization of the intermediate dihydronaphthalene der
173 Schiff base to product Schiff base, a facile aromatization of the latter results in a metastable N-ar
175 e is followed by cleavage of an O-H bond and aromatization of the PNN ligand to form (PNN)RuH(CO)(OH)
177 on with the aryl isocyanates followed by the aromatization of the pyridine/isoquinoline moiety to aff
179 on is stabilized by a combination of partial aromatization of the QM moiety and through-space interac
180 by (optional modification and) base-induced aromatization of the resulting chlorinated oxanorborn(ad
182 roxylation steps, and the third involves the aromatization of the steroid A-ring, unique to aromatase
183 r controlling specific aldol cyclization and aromatization of these mature polyketide precursors, but
186 emonstrate that at high temperatures thermal aromatizations of 2-vinylmethylenecyclopropane (at 700 d
187 provide theoretical insights for the thermal aromatizations of 2-vinylmethylenecyclopropane and 3-vin
188 ing tetrahydrocarbazole and dehydrogenation (aromatization) of this to give the target carbazole (e.g
189 intermediate, which could undergo oxidative aromatization or defluorinative aromatization to form di
190 e, as in the thiopeptide thiostrepton, or an aromatization path to yield the pyridine groups observed
195 which is rapidly obtained by an oxidative de-aromatization process mediated by a hypervalent iodine r
198 ansfer process accompanies the excited-state aromatization, producing a Baird aromatic 8pai core annu
200 echanistic studies for each step (insertion, aromatization, product release, and nitride regeneration
202 ort that a branched primary amine bearing an aromatization-prone moiety, ethyl 4-amino-4,5-dihydrothi
204 -ligand cooperation (MLC) by dearomatization/aromatization provides a unique way for bond activation,
206 ose that this residue may participate in the aromatization reaction (the third step) by acting as a h
208 boxylate (P2C) to picolinate in a remarkable aromatization reaction comprising two redox cycles and a
209 essible via acid-mediated Grob fragmentation-aromatization reaction of 1,4,5,6-tetrabromo-7,7-dimetho
211 n iron(III)-catalyzed cycloisomerization and aromatization reaction produces tetracyclic benzofuran d
212 -mediated one-pot arylation, cyclization and aromatization reaction sequence from 3-acetyl/aroyl-2-pi
214 ne, followed by a cascade of elimination and aromatization reaction sequence to preferentially furnis
215 ddition, and transition metal-free oxidative aromatization reaction sequence utilizing molecular oxyg
216 sized via a facile and mild cyclodehydration-aromatization reaction starting from readily available a
222 es of Hopf pericyclic reactions, followed by aromatization reactions of the annulated polycyclic arom
226 g exothermic hydrogenolysis with endothermic aromatization renders the overall transformation thermod
227 rmation based on double Michael addition and aromatization (retro-Claisen cleavage and amine eliminat
230 talyzed decarboxylative prenyl migration and aromatization sequence as the key step is reported.
231 one-pot C-H alkenylation/electrocyclization/aromatization sequence has been developed for the synthe
233 of K2CO3 in THF ensured a clean deprotection-aromatization sequence to afford the desired heterocycle
234 s-decalin ring, and a 6pi-electrocyclization/aromatization sequence to produce the 2,3-fused carbazol
235 on proceeds through an oxidation/cyclization/aromatization sequence under an atmosphere of O(2) (see
238 ective construction of two new C-C bonds and aromatization sequences under mild and metal-free reacti
239 Both routes avoid the need for a discrete aromatization step and offer significant advantages over
245 ational evidence shows that a combination of aromatization, steric and stereoelectronic effects assis
247 A recently developed deoxyfluoroalkylation/aromatization strategy enables conversion of cyclohexan(
248 hesized by application of Grob fragmentation-aromatization strategy to 3-(benzyloxy)-1,4,5,6-tetrabro
249 tate topochemical polymerization/cyclization-aromatization strategy to convert the simple 1,4-bis(3-p
251 ge stabilization of product arising from the aromatization that accompanies solvent addition to p-qui
252 ation reactions, culminating in an enigmatic aromatization that converts an androgen to an estrogen.
253 cyclopentane carboxylic acids, reluctant to aromatization, the catalytic system facilitates controll
255 n or reaction with a Grignard reagent before aromatization; the latter process gives compounds in whi
256 ) as a base in DMF at 110 C with concomitant aromatization through an elimination of tosylsulfinic ac
257 bstrates not blocked by geminal substitution aromatization to a dipyrromethane is a competing side re
258 action with a carbon nucleophile followed by aromatization to afford alpha-methylated pyrazines and p
259 t room temperature then results in efficient aromatization to benzene derivatives of a regiochemicall
260 ns in regulating HPA activity may be through aromatization to estradiol, or by 5alpha-reduction to th
262 d antidepressant effects, likely mediated by aromatization to estrogen metabolites, in the sucrose pr
264 go oxidative aromatization or defluorinative aromatization to form different carbon-atom insertion pr
265 [4 + 2] cycloaddition loss of a nitrile and aromatization to generate a 1,2,4-triazine derivative.
270 followed by spontaneous proton loss with re-aromatization to provide the tetrahydroisoquinoline prod
271 rature results in smooth loss of bromide and aromatization to resorcinol monomethyl ethers of defined
274 hloride to the reaction mixture, a selective aromatization to yield the corresponding pyrroles substi
276 thesis reaction, followed by elimination and aromatization, to furnish a key pentasubstituted pyridin
279 ethane derivatives by 1,6-conjugate addition/aromatization under mild reaction conditions without any
280 clohex-1-ene-4,5-diols, which are subject to aromatization upon dehydration or Nicholas diol deoxydeh
281 g openings of 2H-azirine followed by in situ aromatization using a catalytic amount of Bronsted acid
283 s five fast radical cyclizations followed by aromatization via a 1,5-H shift with a >93% yield per st
285 n to yield the formal "6-endo" products with aromatization via stereoelectronically assisted C-C bond
286 lly in all testosterone-dose groups in which aromatization was also suppressed, and this decline was
287 conditions and palladium-catalyzed oxidative aromatization was developed for the synthesis of hexahyd
290 Decreases in DXA BMD were observed when aromatization was suppressed but were modest in most gro
291 f experiments examining injury-induced glial aromatization, we identified aromatase in radial glia of
294 recursors followed by 6pi-electrocyclization/aromatization, while isomeric TD-syn-TBDT and TD-anti-TB
295 adducts with Fe2(CO)9 followed by oxidative aromatization with 2,3-dichloro-5,6-dicyano-1,4-benzoqui
296 lic addition to the aldehyde and dehydrative aromatization with concomitant loss of formic acid led t
297 lly and then subjected to thermally promoted aromatization with elimination of sulfur(IV) oxide and a
299 equential Diels-Alder reaction and oxidative aromatization with the preformed glycosyl diene and dien
300 Finally, the contribution of testosterone's aromatization within the dentate gyrus was assessed by l