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1 the thiol derivatization yield is striking, as reflected by 100% conversion of protein beta-lactoglo
2 al carbon dioxide partial pressure (P(aCO2)) as reflected by 3 to 5 Torr reductions in end-tidal carb
3 , and increased hepatic insulin sensitivity, as reflected by a 2-fold greater suppression of endogeno
4 also increased in the SirT1 ASO treated rats as reflected by a 25% increase in the glucose infusion r
5 d HRAS signaling capacity in cells, however, as reflected by a 4-fold increase in the association of
6 for clinical multiple sclerosis progression as reflected by a composite disability measure including
7 n attenuation of chemically induced colitis, as reflected by a decrease in macroscopic and microscopi
8 flammation, and/or hepatocellular ballooning as reflected by a decrease of >/= 2 points in the nonalc
9 ATP concentration were found to be reduced, as reflected by a decrease of A578 values and viable cel
10 as that develops over the course of a trial, as reflected by a drift-rate offset, provides the stimul
11 Ps into target molecules are in high demand, as reflected by a flurry of methods for BCP synthesis in
12 greater adherence to the Mediterranean diet, as reflected by a higher Alternate Mediterranean Diet Sc
13 to acquire a full-blown GC T(FH) phenotype, as reflected by a higher ratio of GC T(FH)/non-GC CD4(+)
15 to exosite I, exosite II is also disordered, as reflected by a loss of affinity for the gamma'-peptid
18 ffect was more pronounced in Windsor variety as reflected by a lower percentage of ripe berries and s
19 at 1 and 6 months (P = 0.0132; P = 0.0052), as reflected by a lower proportion of patients using ana
20 macro and microscopic anatomy of lymph nodes as reflected by a marked decrease in size of inguinal ly
21 d Sca-1 expression by lin(-) c-kit(+) cells, as reflected by a marked increase in BrdU-negative lin(-
22 resistant to high-fat diet-induced obesity, as reflected by a marked reduction in adipose tissue mas
23 nt improved the accuracy of risk prediction, as reflected by a net reclassification improvement of 22
24 shape of the repertoire was stable over time as reflected by a number of repertoire characteristics,
25 initial androgen-deprivation therapy (ADT), as reflected by a prostate-specific antigen (PSA) level
26 hanges upon iron binding and core formation, as reflected by a quick alteration of its radius of gyra
27 ue macrophages is rapidly suppressed by ART, as reflected by a rapid drop in plasma viral load and a
28 rnalized and inactivated (95% in <= 2 hours) as reflected by a reduced replication in epithelial cell
29 changes in metabolic status during puberty, as reflected by a reduction in Tacr3 (and, to a lesser e
30 f tissue injury and fibrosis upon treatment, as reflected by a reduction of collagen deposition to a
31 to a number of factors, but rising incidence as reflected by a rising sex ratio, influenced by gene-e
32 significant impact on the folding structure, as reflected by a significant lowering of the T(m) value
33 urons and that amyloidogenic APP processing, as reflected by Abeta1-40/42, is associated with mature
34 munication among large-scale brain networks, as reflected by abnormal resting-state functional connec
36 ed to R-loop-driven DNA damage at those loci as reflected by adjacent gamma-H2AX accumulation and ssD
38 2 of gestation showed decreased fetal growth as reflected by all growth parameters at 20-34 weeks, le
40 n between excitatory and inhibitory control, as reflected by alteration in GABAergic and glutamatergi
41 eurons lacking Klf-9 show delayed maturation as reflected by altered expression of early-phase marker
42 of sleep-deprived mice, and plastic changes as reflected by AMPA receptors phosphorylation are also
43 ability of the activation loop is decreased, as reflected by an approximately 35% increase in B facto
44 known types of antenatal Bartter's syndrome, as reflected by an earlier onset of polyhydramnios and l
45 sociated with an increase in global immunity as reflected by an enhanced delayed type hypersensitivit
46 d enhanced glucocorticoid negative feedback, as reflected by an exaggerated cortisol suppression foll
47 es impair interactions between its proteins, as reflected by an increased A-W interfacial shear visco
48 endent predictor of MR reduction at 6 months as reflected by an increased odds of MR response (odds r
49 ge the additional use of top-down resources, as reflected by an increased preference for repeating st
50 kely due to impaired maturation of NK cells, as reflected by an increased ratio in immature to mature
51 ransduction of MSC suppressed chondrogenesis as reflected by an inhibition of Col2a1 and Col10a1 expr
54 ular thrombus formation and improve outcome, as reflected by better motor function, reduced brain les
55 roliferation of lin(-)c-kit(+)Sca-1(+) cells as reflected by BrdU incorporation, phenotypic inversion
56 lar smooth muscle cell (VSMC) proliferation, as reflected by bromodeoxyuridine incorporation, was mar
57 eas the knockout is detrimental to the heart as reflected by cardiac hypertrophy and malfunction at 1
58 c expression of CCHFV NSs induces apoptosis, as reflected by caspase-3/7 activity and cleaved poly(AD
59 minus ends, resulting in failed cytokinesis as reflected by cell wall stubs in leaf epidermal cells.
61 Asymmetric decision threshold adjustments, as reflected by changes in the starting point of evidenc
64 of abdominal fat deposit, profibrotic state (as reflected by circulating PICP), reduced insulin sensi
65 ncipal effect of As doping on crystal growth as reflected by considerably reduced average particle si
66 dough improved the bread sensory properties, as reflected by consumer preference and GC/MS analysis o
67 ate matter (PM) with newborn telomere length as reflected by cord blood and placental telomere length
68 sted life expectancy, and cost effectiveness as reflected by costs per quality-adjusted life-year gai
70 kidneys having increased oxidant/ER stress, as reflected by DCF/dihydroethidium staining, perturbed
71 renal denervation also reduced inflammation, as reflected by decreased accumulation of total leukocyt
72 urogranin levels predicted cognitive decline as reflected by decreased Mini-Mental State Examination
73 54.22, P < .001); faster disease progression as reflected by decreased Mini-Mental State Examination
74 bules and activate terminal differentiation, as reflected by decreased Osterix, Col1a1, and Dspp expr
75 Patients with FMR have inadequate adaptation as reflected by decreased ratios of leaflet area and are
76 e manifest severe hepatic insulin resistance as reflected by decreased suppression of endogenous gluc
77 CRF dose-dependently disrupted performance as reflected by decreases in correct responding, increas
79 cantly influenced by the metrical structure, as reflected by differences across beat type for both pe
80 rds are processed and remembered differently as reflected by different ERP patterns for the two types
81 assay showed variation in compaction level, as reflected by different FRET efficiency populations, t
82 revealed massive transcriptome reprogramming as reflected by differential expression of approximately
84 r immunity (memory) was severely compromised as reflected by diminished CD8 T-cell recall responses a
85 associated with increased LV contractility, as reflected by ejection fraction (p = 0.02), rate of pr
88 en myofibroblasts and cardiomyocytes >5-fold as reflected by elevated connexin 43 and consortin trans
89 ystemic activation of the complement cascade as reflected by elevated levels of the key regulator C3a
90 ost response during experimental melioidosis as reflected by enhanced bacterial growth at the primary
91 ns in the mitochondrial protein homeostasis, as reflected by enhanced expression of canonic mitochond
92 Our data show OAbeta activates senescence as reflected by enhanced expression of p16(INK4a), MMP1,
93 used As(III) as a supplemental energy supply as reflected by enhanced growth and increased cellular l
94 tivity is impaired in a phoQ knockout strain as reflected by enhanced growth of this strain in rice l
95 nse during the first 4 days after admission, as reflected by enhanced inflammation, stronger endothel
97 otection from Plasmodium falciparum malaria, as reflected by fewer symptomatic cases of malaria, lowe
98 sponse was related to endothelial phenotype, as reflected by flow-mediated dilation and expression of
99 f the (1)C(4) complex to nucleophilic attack as reflected by free energy, C1-O1/O5-C1 bond length elo
100 ficant increase in spinal cord remyelination as reflected by g-ratio analysis within the thoracic and
101 re unrecognized toxicity to GABAergic cells, as reflected by GAD67 mRNA expression histochemistry, in
102 in expression ratio across the mouse retina, as reflected by ganglion cell responses in vitro, and pr
103 larger and had 32% greater size inequality, as reflected by Gini coefficients, than those with sever
104 pment of allergic sensitization in childhood as reflected by global variations in sensitization patte
105 isier neural activity than their classmates, as reflected by greater activity in the absence of audit
106 ed vasodilatory effects, compared with LeTx, as reflected by greater or earlier central venous pressu
108 iabetic complications, and glycemic control, as reflected by HbA1c reduction, results in decreased ri
110 that display a Th1/Th17 phenotypic profile, as reflected by heightened interferon gamma and interleu
111 ramming of human normal prostate fibroblasts as reflected by high levels of alpha-SMA, IL6, and MMP9.
112 l cortex and the posterior cingulate cortex, as reflected by higher correlation with subjective value
113 9%; P=0.008), and worse diastolic function, as reflected by higher E/E' ratio (11.7+/-0.2 versus 10.
114 eparanase also impacts exosome protein cargo as reflected by higher levels of syndecan-1, VEGF, and h
115 hat activation of adaptive immune responses, as reflected by higher proportions of circulating CD4(+)
116 hma patients showed small airway dysfunction as reflected by higher R5 -R20 and lower X5 values.
117 meability was increased to a greater extent, as reflected by higher serum levels of lipopolysaccharid
118 emales adapted more slowly to the VR stimuli as reflected by higher use of total (p = 0.007), low fre
119 n of nuclear proteins; and DNA accessibility as reflected by histone markings and increased mononucle
120 DNA alkylating drug compared to WT parasites as reflected by impairment of oocyst formation and sporo
121 ient mice were resistant to ischemic injury, as reflected by improved kidney function, reduced histol
122 the degree of injury to nigrostriatal axons, as reflected by in vitro fiber length density measures,
124 ittent hypoxia induces metabolic dysfunction as reflected by increased body weight and adiposity inde
125 factor deprivation stress-induced apoptosis as reflected by increased DNA fragmentation and caspase
126 acid delivery/triglyceride reesterfication, as reflected by increased expression of CD36, acyl-CoA:d
127 umor microenvironment manifested DNA damage, as reflected by increased expression of gamma-H2AX.
128 pm-mediated inhibition of myosin attachment, as reflected by increased F-actin-Tpm motility that pers
129 osis was exhibited after 6 weeks of feeding, as reflected by increased fecal LPS and bacterial metabo
130 known consequence of hepatic TR activation, as reflected by increased hepatic mitochondrial respirat
131 D183 generally compromise substrate affinity as reflected by increased K(M) values but have less pron
132 o increased amyloidogenic processing of APP, as reflected by increased levels of sAPPbeta and decreas
133 rated development of pneumococcal pneumonia, as reflected by increased levels of viral and bacterial
134 levels and by accelerating erythroid output as reflected by increased maturation of erythrocyte prog
135 resulting from increased hepatic lipogenesis as reflected by increased mRNA levels of fatty acid synt
136 ) are viable, but dark metabolism is altered as reflected by increased nighttime malate, starch, and
137 esponsible for the reduced (18)F-FLT uptake, as reflected by increased pCO(2) and reduced pH and lact
138 ncreased in fructose chow-fed XBP1Delta mice as reflected by increased phosphorylated eIF2alpha, HSPA
139 y occurred exclusively in the two older ages as reflected by increased serum alanine aminotransferase
140 microinjections stimulated 'wanting' to eat, as reflected by increases in intake of palatable sweet c
141 ction, and attention were produced by PACAP, as reflected by increases in reward thresholds, decrease
142 translate the SV2 puncta into synaptic input as reflected by increases in the frequency of spontaneou
143 pite increasing complexity of case selection as reflected by increasing number of patients with pancr
144 , certain mutants exhibited reduced toxicity as reflected by induced indoleamine 2,3-dioxygenase (IDO
145 lantation partially improves liver pathology as reflected by inflammatory response, fibrosis, and apo
146 ectively; P < 0.001), as did body cell mass, as reflected by intracellular water (change, -1.0 kg [CI
147 ine that exerts immunosuppressive functions, as reflected by its ability to induce regulatory T (Treg
150 pha2-chimaerin hypersensitive to C1 ligands, as reflected by its enhanced ability to translocate in r
151 nd for the association of Nedd4-2s with Gag, as reflected by its incorporation into virus-like partic
152 timing based on the status of the infection as reflected by its potential for an unacceptably renewe
153 y responds to intracellular nitrogen levels, as reflected by its stronger NCR-sensitivity, weaker res
154 n predominantly responds to TorC1 regulation as reflected by its weaker NCR sensitivity, stronger res
156 ell as to protection of normal immune cells, as reflected by lenalidomide studies across multiple typ
157 howed increases in pro-inflammatory factors, as reflected by levels of mRNA and protein, expression o
158 nder the curve, 0.85; 95% CI, 0.83-0.88) and as reflected by likelihood ratio and added value analyse
159 C stored for 7 days exacerbated liver injury as reflected by liver necrosis and enhanced apoptosis (p
160 modulation of vascular smooth muscle cells, as reflected by loss of alpha-smooth muscle cell actin a
162 r levels for N-nitrosamines, HANs, and HAMs, as reflected by lower concentrations of these DBPs measu
164 cient at high salinity than at low salinity, as reflected by lower glucose consumption, lower metabol
165 ed in transgenic compared to wild-type mice, as reflected by lower levels of the specific spectrin br
166 with mild MS showed significantly better BCG as reflected by lower PCI values in comparison to the ot
167 d strongly attenuated systemic inflammation, as reflected by lower plasma cytokine levels, maintenanc
168 otected from fat-induced insulin resistance, as reflected by lower plasma glucose concentrations duri
169 SRT2104 inhibited activation of coagulation, as reflected by lower plasma levels of the prothrombin f
171 d with placebo, reduced disease progression, as reflected by lung function, exercise tolerance, and p
172 ATP and shows aberrant purinergic signaling, as reflected by marked deficiency of the transcription f
173 severely disrupted bone marrow homeostasis, as reflected by marked expansion of hematopoietic stem a
176 ed interference within transgenes in plants, as reflected by misexpression of the introduced gene and
177 at increased neural efficiency and capacity, as reflected by more "youth-like" brain response pattern
178 ctral inhomogeneity than the ferric species, as reflected by multiple shoulders in the optical absorp
179 vels: (1) the degree of tumor "foreignness," as reflected by mutational burden and expression of vira
180 ure miRNAs, hepatic function was maintained, as reflected by normal blood glucose, albumin, cholester
182 atory T cells are associated with CNS repair as reflected by oligodendrogenesis and remyelination.
183 e, limiting biomechanics research potential, as reflected by only few commercial biomechatronics syst
184 nd that retention of a newly acquired skill, as reflected by performance in the second day of practic
185 gen-activated protein kinase (MAPK) activity as reflected by phospho-extracellular signal-regulated k
186 Tsc1 and stimulates the activity of mTORC1, as reflected by phosphorylation of the ribosomal protein
187 ka, progressing westward across the caldera, as reflected by post-caldera effusive lava eruptions and
189 photocatalysis can address these challenges, as reflected by recent intensive scientific endeavours t
190 f neonatal rats to oral E. coli K1 infection as reflected by reduced bacterial intestinal colonizatio
192 nd are associated with decreased bioactivity as reflected by reduced drug-induced cellular proliferat
193 pa B and decreased myogenic differentiation, as reflected by reduced expression of myogenin and impai
194 400 milliseconds after feedback presentation as reflected by reduced feedback-related negativity (ADH
195 tions were accompanied by structural changes as reflected by reduced fractional anisotropy values, as
196 associated with hepatic insulin resistance, as reflected by reduced insulin suppression of hepatic g
197 isting plaques was reduced by FXa inhibition as reflected by reduced macrophages (-39.03%, p < 0.05),
198 hs (n=8), hibernating myocardium was present as reflected by reduced resting LAD flow (0.75+/-0.14 ve
199 and a decrease in endothelial permeability, as reflected by reduction of transendothelial resistance
200 icant reduction in whole-brain MAO-A binding as reflected by reductions in 10 of 11 brain regions.
202 tionally inhibits osteoblast differentiation as reflected by reductions in the expression of osteobla
204 rally linked to an attended visual stimulus, as reflected by robust cross-modal spreading-of-attentio
205 er than the HEMORR(2)HAGES and ATRIA scores, as reflected by ROC analysis, reclassification analysis,
206 showed the highest GSH, Grx1 and Trx1 levels as reflected by RT-PCR, Western blotting and immunohisto
207 ing was paralleled by behavioral adaptation, as reflected by SD-dependent changes in learning rate.
208 o model 1 in detecting undiagnosed diabetes, as reflected by several significant improvements, includ
209 all immediate over the large delayed reward, as reflected by shorter indifference points) compared to
210 ronic HF enhances skeletal muscle energetics as reflected by shorter PCr recovery half-times (PCr t(1
211 onfigured in many ways during TRV infection, as reflected by significant changes in the levels of sug
212 ed clearance of radioactivity from the brain as reflected by significant increases in k (E,brain) (fr
213 ed clearance of radioactivity from the brain as reflected by significant increases in kE,brain (from
214 ar permeability, and coagulation activation, as reflected by significant reductions in lung edema, he
215 n prevent retinal degeneration in rd10 mice, as reflected by significant structural, biochemical, ele
216 CU patients, the FGF19 response was blunted, as reflected by significantly lower FGF19 elevations at
217 of blood-borne lactate in the T1D subjects, as reflected by similar (13)C fractional enrichments in
218 etween the derivation and validation cohorts as reflected by smooth calibration curves analyses and a
220 of hydrogels results in intriguing dynamics, as reflected by spontaneous jumping, bouncing, trampolin
223 trongly promoted osteoblast differentiation, as reflected by stimulation of alkaline phosphatase acti
224 ed with segmentation of ongoing experiences, as reflected by subjectively perceived event boundaries
225 kappa8 B cells promotes an anergic phenotype as reflected by suboptimal responses to BCR cross-linkin
226 wide significant association with longevity, as reflected by survival to ages beyond 90 years, at a n
227 esponding changes in local sleep regulation, as reflected by SWA, providing evidence for a tight rela
229 ly, there was a decreased rate of apoptosis, as reflected by terminal deoxynucleotidyltransferase-med
230 entry, and assessed the impact of infection as reflected by the ability of HSCs to transfer virus to
231 ial rescue was further corroborated in vivo, as reflected by the anergic phenotype of most rescued B
232 increased risk for Alzheimer's disease (AD), as reflected by the Apolipoprotein E epsilon4 (APOE-e4)
234 arameters over 24 months with high accuracy, as reflected by the area under the curve measures: JSW 8
235 on reduced the quality of the muscle tissue, as reflected by the attenuation, revealing increased int
237 the presence of subclinical atherosclerosis, as reflected by the burden of coronary artery calcificat
238 evidenced by the N2pc) and vWM maintenance (as reflected by the CDA) were modulated by target numero
239 et was more prominent among active patients, as reflected by the changes in GCIPL thickness (p = 0.02
240 the same stage share common functionalities as reflected by the co-expression patterns, which are di
241 r SGLT3 in coordinating intestinal function, as reflected by the concomitant modulation of Gabsorp an
242 g automatic processing of auditory deviance, as reflected by the duration + frequency double deviant
243 ng, trachea, and bladder of exposed animals, as reflected by the elevation of background cII mutant f
244 terparts than products of direct conversion, as reflected by the establishment of target cell-type ge
245 t the changed spontaneous neuronal activity, as reflected by the fALFF, in these regions may be impli
246 type can control an ecosystem's SOC nature, as reflected by the finding that higher labile C in bamb
248 on of MPPEG increases the efficiency of EAFP as reflected by the generation of hexaPEGylated Hb and t
249 ficacy of new antihyperglycemic medications, as reflected by the guidance of the US Food and Drug Adm
251 conferring vulnerability to opiate addiction as reflected by the high comorbidity of opiate abuse wit
252 especially in immunocompromised individuals, as reflected by the high mortality rate of 33 to 46% and
253 ciated with a tumor-promoting colonic milieu as reflected by the high rates of adenomatous polyps in
254 ures, a TH17-dominant response was observed, as reflected by the higher amounts of IL-17A and IL-17F
255 d to an upstream shift of the +1 nucleosome, as reflected by the Hmo1 extension and core promoter reg
256 omal cells, which inhibited decidualization, as reflected by the impaired induction of decidual marke
257 on the glycosylation state of the receptor, as reflected by the inability of overexpression of RPNI
258 ation of routes induced a Th1-type response, as reflected by the induction of stronger antigen-specif
259 he progress of the MR during UHT processing, as reflected by the levels of furosine found in samples.
261 overexpressed Prdx6 reduced oxidative stress as reflected by the lower levels of oxidized phospholipi
264 he strength of N-H...S(gamma) hydrogen bonds as reflected by the midpoint reduction potential, provid
265 layed different levels of proneural activity as reflected by the number and functionality of sense or
266 be the causative agent of multiple sclerosis as reflected by the number of potential triggering mecha
267 cularly dependent on mitochondrial function, as reflected by the observation that diseases of mitocho
268 he excitability of the primary motor cortex, as reflected by the phase-amplitude coupling between the
269 erapy reduced the virus-induced inflammation as reflected by the presence of lower amounts of proinfl
270 creased the excitability of the BLA network, as reflected by the pronounced increase of evoked field
271 atio of contacts, and the broad data quality as reflected by the proportion of mappable reads of data
274 icular filling pressure response to exercise as reflected by the ratio of peak early diastolic mitral
275 of magnitude higher than any other pathogen--as reflected by the recent emergence of SARS and Influen
276 ynamic interaction with its bacterial hosts, as reflected by the reciprocal morphologic and physiolog
277 ndosomes precedes the maturation of the SGs, as reflected by the recruitment of Rab27B, and allows th
278 ction have undergone a selective bottleneck, as reflected by the reduction in population size and div
279 ts with ADHD showed more simplistic learning as reflected by the reinforcement learning model (exceed
280 their responses to the same sensory stimuli, as reflected by the reliability and temporal precision o
281 hly accepted by the general adult population as reflected by the response rate (95.85%) and the low p
284 naptic calcium ion channels appeared normal, as reflected by the similar characteristics of calcium c
285 We found that cerebral glucose metabolism, as reflected by the VTCA, was not significantly differen
286 s lipid metabolism and promotes weight loss, as reflected by the wasting observed in glucagonoma pati
287 n a chiral environment on benzaldehyde lyase as reflected by their circular dichroism signatures.
288 se were fundamentally influenced by P status as reflected by their high correlation with P concentrat
289 n their attention throughout the entire CPT, as reflected by their progressively slower (B = 0.002, S
290 ey regulators of mitochondrial redox status (as reflected by thiol/disulfide exchange) by maintaining
293 een behavioral disorders and bowel disorders as reflected by treatment response and effect on behavio
294 , as reflected by the FLI, and dyslipidemia, as reflected by triglycerides, may partly explain the as
296 most potently promote human pDC activation, as reflected by type I IFN release, which was dependent
297 without inhibiting Th17 lineage commitment, as reflected by unaltered RORgammat, STAT3, and FoxP3 ex
300 iety of ESD service models had been adopted, as reflected by variability in the ESD consensus score.