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1 if they have achieved and remain in response at present.
2 d worldwide, for which there is no treatment at present.
3 ation of cardiovascular diseases, is unclear at present.
4 re liquid water was more abundant than it is at present.
5  use of PICSI, therefore, is not recommended at present.
6 asis for RAF regulation is poorly understood at present.
7 e is not available and resources are lacking at present.
8  precise diagnosis, there is no cure for CMT at present.
9 f patients managed conservatively is ongoing at present.
10 e limited value in diagnostic testing in DCM at present.
11 ek following drug administration, as well as at present.
12  the developmental relationships are unclear at present.
13 onic lung disease, lacks curative treatments at present.
14 an any other available software or webserver at present.
15 uch cross talk are only partially understood at present.
16 ea level was substantially higher than it is at present.
17 pletely understood and remains controversial at present.
18 ms to be possible under favorable conditions at present.
19 post-eruption ages, and are also dwarf novae at present.
20 ls with superior performances remain elusive at present.
21 of radiogenic Xe from the mantle higher than at present.
22 past sea level changes, appear to be vibrant at present.
23  and Amery Ice Shelves, retain surface water at present.
24 er, their functional significance is unclear at present.
25 lular machinery has been described in plants at present.
26 h there is no real time monitoring technique at present.
27 ral treatments specific to these two viruses at present.
28 tentiates tumor cell invasiveness is unclear at present.
29 mpared to the mature fibrils, remain unknown at present.
30 itions are only variably applicable and used at present.
31 proteins other than PSMA, cannot be excluded at present.
32 runoff from ice sheets is poorly constrained at present.
33 ludes meaningful comparisons and conclusions at present.
34 , no specific antiviral therapy is available at present.
35 y, permeability and stability than available at present.
36 of Canadian organ-specific allocation models at present.
37 eficial, but no such therapies are available at present.
38 iables, which are not available in the field at present.
39 during 1,600 to 1978 to - 0.7 m w.e year(-1) at present.
40 ontinents were only slightly more mafic than at present.
41  state-of-the-art binary organic solar cells at present.
42 ary infections per infected individual to ~1 at present.
43 t feasible way to reduce the epilepsy burden at present.
44  340 M for mid-century, versus roughly 250 M at present.
45 hen the glacier is significantly larger than at present.
46 , and there is a lack of effective treatment at present.
47 on-coupled membrane transport proteins known at present.
48                                              At present, 14 therapies targeting 6 PAH-specific molecu
49                                              At present, (18)F-FDG PET imaging is the most widely use
50                                              At present, 531 306 and 2 941 669 primer pairs exist acr
51                                              At present, (64)Cu(II) labeled tracers including (64)CuC
52                                              At present, 7.1% of the ocean south of 40 degrees S is u
53                                              At present a paucity of information exists regarding the
54                                              At present, a double-digit number of efforts are devoted
55    The sensory tests are time-consuming, and at present, a fast analytical method to detect this defe
56 the assembly of eukaryotic genomes; however, at present additional scaffolding is needed to achieve c
57                                              At present, AFND contains >1600 populations from >10 mil
58                                              At present, all intraoperative techniques significantly
59 or the analysis of RNA MS data is inadequate at present and does not allow high-throughput processing
60 more tailored assessment and management than at present and enable future research into the effect of
61 s also include reflections on the discipline at present and in the future.
62           Finally, due to its infrequent use at present and its dependence upon long product lifespan
63 w (Mammalia, Soricidae, Cryptotis mexicanus) at present and the Last Glacial Maximum (LGM).
64 tic cyclones may have been more intense than at present, and may have produced waves larger than thos
65 uch summer insolation is near to its minimum at present, and there are no signs of a new ice age.
66                                              At present, antibiotic stewardship is informed by a 'use
67                                              At present, AtWRI1-interacting partners remain largely u
68                                              At present, bacterial protein acetylation plays a promin
69                                              At present, based on an overall balance of efficacy and
70                                              At present, based on whole genome sequencing, sequences
71                                              At present, both the binding site and NPQ mechanism of O
72 be directly observed in most oceanic regions at present, but that this may become possible between 20
73 n the UK have a return time of 100-300 years at present, but, without mitigating greenhouse gas emiss
74 nity is significantly smaller than simulated at present by global chemical transport models for this
75 nthesized from electrical sources is limited at present by the sluggish oxygen evolution reaction (OE
76                                              At present, caregivers receive little guidance or inform
77                                              At present, CE can be divided into two categories, namel
78                                              At present, CF(3)CHN(2) can only be generated by oxidati
79                                              At present, CGE-LIF relies on the green fluorophore 8-am
80                                              At present, checkpoint-specific molecular imaging is bei
81                               Unfortunately, at present, chocolate products contain too much fat, lea
82                                              At present, clinicians have no empirically validated mec
83 m cells or induced pluripotent stem cells is at present close to reality, and we are currently awaiti
84                                              At present, combs with wide spectra are usually generate
85                                              At present, counting atoms in a one-kilogram sphere made
86  Although the future of the virus is unknown at present, countries should continue to share their exp
87                                 Furthermore, at present, data aggregation and visualization are labor
88 conditioned on the number of species sampled at present day and, in some cases, a specific time inter
89  significant impact when the climate is held at present-day conditions.
90                                              At present, diagnosis of cannabis-related allergies pred
91                                              At present, diagnostic accuracy with positron-emitting r
92 ated prior to 2010, indicating that PNSP are at present dominated by descendants of NVT clones presen
93 red locally or globally cannot be determined at present due to the lack of a dataset of the marine ve
94 sed to control bovine tuberculosis in cattle at present, due to its variable efficacy and because it
95                                     However, at present, each existing platform relies on a defined e
96                                              At present, electrochemical mechanisms are most commonly
97                                              At present, energy interventions are failing to reach op
98           Nonetheless, our results show that at present, EWIs do not provide reliable and consistent
99                                              At present, faecal microbiota transplantation is only re
100  of bioresorbable pressure sensors available at present fall short of many clinical needs.
101                                              At present, few methods exist to remediate prion-contami
102 te appropriate candidate surrogate endpoints at present for clinical trials in this frequently dismal
103  improving, they remain too noisy and costly at present for population-level studies.
104                                              At present, fumonisin determination is performed using c
105 nics, reproductive biology and, particularly at present, genomic architecture, yet all scenarios pres
106                                              At present, glycan characterization often relies on a co
107                                              At present, GXD includes over 1.5 million expression res
108          However, drug discovery efforts are at present hampered by an inability to precisely control
109                                              At present, hematopoietic stem cell transplantation is t
110                                              At present, histone marks are used to identify and defin
111                                              At present, how simple steatosis progresses to NASH rema
112                                              At present, however, the very short lifetimes of the hea
113                                              At present, however, there is no consensus on the phenot
114 t rare in the past and may potentially occur at present in critically pressurized reservoirs.
115                                              At present, in vitro antimicrobial susceptibility testin
116 per year from Southeast Asian coal emissions at present, increasing to 69660 (40080-126710) by 2030.
117                                     However, at present, insufficient evidence exists showing that SL
118                                              At present, intralesional multi-injection of triamcinolo
119                                              At present, investigators are primarily focused on impro
120 largely on their metabolism in plants, which at present is poorly understood.
121                                      Because at present it is difficult to tell where sign stops and
122                                              At present it is unclear how common reinfection with SAR
123                                              At present, it involves administering a train of pulses
124                                              At present, it is not clear how twitching motility emerg
125                                              At present, it is not known which tau species are seed-c
126                                              At present, it is not possible to define a quantity with
127                                              At present, it is not possible to predict which patients
128                                              At present, it is not understood how the MAC perturbs th
129                                              At present, it is thought that temperature-dependent emi
130                                              At present, it is unclear whether and how TDP-43 and tau
131                                              At present, it is unclear whether the cell fate programm
132                                              At present, it is unclear whether the well-documented in
133                                              At present, it is unknown whether or not ZIKV can infect
134  of FTLD-related biomarkers by psychiatrists at present, it is very difficult to separate patients wi
135                                              At present, it remains debated whether and how membrane
136                                              At present, it requires ~8 d of wet-laboratory work, 15
137                                              At present, it's unclear whether HY5 uses additional mec
138                                              At present, judicious transfusion of RBCs is the primary
139  to different modes of collective motion is, at present, lacking.
140 y, the consequences for carrier dynamics are at present less clear, particularly on ultrafast timesca
141                                              At present, limited evidence explains how genetic risk f
142                                              At present, little is known about the conformational dyn
143                                              At present, little is known about the in vivo metabolic
144                                              At present, little is known about the neurocognitive mec
145                                              At present, little is known about the physiological rele
146                                     However, at present, LPOS requires 3 separate reaction steps and
147                                              At present, LULC change is rarely included in models of
148 of many migratory bird species across Europe at present, male-biased small populations may be increas
149                                              At present, marine life encounters a wide range of envir
150                                              At present, models range from ligand-independent recepto
151 ated for small benign and peripheral tumors, at present more than half of LLRs are performed in malig
152   A newly found minor state, undisclosed by, at present, more than 500 crystal structures of T4L and
153                                              At present, most ChIP-seq analysis tools adopt the comma
154                                              At present, most FFA4 ligands are carboxylic acids that
155                                              At present, most patients undergo cataract surgery in bo
156                                              At present, multiple classes of agents with distinct mec
157  links with such basal annelids as Ipoliknus at present must remain conjectural.
158                                              At present, mutations in six genes involved in SR calciu
159                                              At present, nearly 20% of neonatal diabetes cases have u
160 dependent predators and their performance is at present neglected in the CCAMLR Ecosystem Monitoring
161                                              At present, neural mechanisms underlying systems-level c
162 chronic kidney disease progression; however, at present no antifibrotic therapies exist(1-3).
163                                              At present no effective therapeutic strategy to ameliora
164                            However, there is at present no method to detect these non-separable state
165                            However, there is at present no simple way to measure this enzyme's activi
166 actors contribute substantially to CAD risk, at present no well-established specific genetic risk fac
167                                              At present, no accurate method exists to predict the dev
168                                              At present, no approved pharmacotherapies are available
169                                              At present, no definitive solution exists for the challe
170                                              At present, no effective cure or prophylaxis exists for
171                                              At present, no effective treatment exists to prevent its
172                                              At present, no evidence suggests that implanting a CIED
173 rdinia began in the first millennium BC and, at present, no more than 56-62% of Sardinian ancestry is
174                                              At present, no pharmacological intervention can be recom
175                                              At present, no similar consensus exists to guide imaging
176                                              At present, no single approach has been established for
177                                              At present, non-invasive tests to identify BE patients f
178                                              At present, noninfected patients on biologicals for the
179                                              At present, numerous G. lucidum products have emerged in
180                                              At present one group of scientists and clinicians feel t
181                                              At present only a limited number of non-periodic feature
182                                              At present, only short-term increases in survival can be
183                                              At present, over 90,000 MOFs have been synthesized and o
184                                              At present, predictors of severe disease and the efficac
185                                              At present, processed data from these experiments are di
186 mber of material-binding sequences is large, at present, quantitative materials-binding characterizat
187                                              At present, rapid molecular diagnostics (RMDs) that can
188 ing data-model comparisons and suggest that, at present rates of human emissions, there will be more
189 phenotypes and their spatial context are not at present reflected in the histological stratification
190                                              At present relatively low radiation exposures, breast sh
191                                              At present, relatively few human health or epidemiology
192                                              At present, relatively little is known about how growth
193                                              At present, remote functionalities are basically limited
194                                              At present, resistance to artemisinins or key partner dr
195  imputed genotypes, overcoming barriers that at present restrict the application of genome-wide assoc
196 a world with much lower atmospheric pO2 than at present, resulting in severe ecological constraints a
197                                              At present, senescent cells are identified by the combin
198 ates and other industrialized countries and, at present, short of surgical joint replacement, there i
199                                              At present, strong competition has put these crops at ri
200        Two different types of mechanisms are at present suggested for the O-O bond-formation step in
201                                              At present, techniques like high-performance liquid chro
202 wever, no large-scale assembly method exists at present that maintains the intrinsic properties of th
203 development and distribution of sea ice, but at present the evidence of polar ecosystem feedbacks on
204                                              At present the functions of a large fraction of genes ar
205                                     However, at present the mechanism of activation and metabolism of
206                                              At present the method is only reliably used to assess th
207                                              At present the only experimental technique for the quant
208                                              At present, the analysis of multi-dimensional, massive g
209                                              At present, the cellular proteins involved in the underl
210                                              At present, the choice of noninvasive testing for a diag
211                                              At present, the clinical utility of genetic risk predict
212                                     However, at present, the construction of Borromean linked organic
213                                              At present, the current mainstay of management for most
214                                              At present, the degree to which differences between pigm
215                                              At present, the dynamics and relative importance of sign
216                                              At present, the efficiency of state-of-the-art all-PSCs
217                                              At present, the extent to which the diagnosis and treatm
218                                              At present, the freeze-drying method obtains dried produ
219                                              At present, the geographical origin of extra virgin oliv
220                                              At present, the identity of the mRNA targets they regula
221                                              At present, the knowledge on the negative regulation of
222                                              At present, the known genetic risk loci are largely unch
223                                              At present, the major parameter that can explain the sel
224                                              At present, the mechanism(s) by which familial VPS35 mut
225                                              At present, the methods employed for detecting blood pro
226                                              At present, the molecular basis of terminal drought tole
227 the whole-genome sequence of an organism is, at present, the most comprehensive descriptor of the org
228 us (HBV) and hepatitis C virus (HCV) remain, at present, the most important global risk factors for H
229                                              At present, the most successful groups of isotopes for t
230                                              At present, the NAM is the only class of AMPAR ligands t
231                                              At present, the only available method for determining a
232                                              At present, the potential role of Gs-coupled GPCRs in re
233                                              At present, the precise cellular pathways affected by th
234                                              At present, the reason why some patients recover without
235                                              At present, the receptor conformational changes that occ
236                                              At present, the role of autologous cells as antigen carr
237                                              At present, the selection process that determines which
238                                              At present, the structural consequences that result from
239                                              At present, the sugar industry is influencing dental res
240                                              At present, the treatment for ADPKD is largely supportiv
241                                              At present, the uncertainty on this constant is dominate
242                                              At present, the vast majority of what is known about neu
243 on the exposome is daunting and not feasible at present; the undertaking may never be fully realized.
244                                              At present, therapies are not guided by individual risk
245 for glucose homeostasis and lowering IR, but at present there are insufficient data to conclusively d
246 behavioural and cognitive symptoms for which at present there are no disease altering treatments.
247  early indicator of possible VBDS, for which at present there are no known means of prevention or the
248                                     However, at present there has been no consistent analysis of the
249                                              At present there is a focus on therapies for severe infe
250 ancing insight should improve clinical care, at present there is a substantial discrepancy between re
251 t body of evidence is limited and we believe at present there is equipoise and further conclusive stu
252                                        Thus, at present there is no compelling evidence that clonalit
253 cognized as a sexually transmitted pathogen, at present there is no defined public health response to
254                                              At present there is no established optimal approach for
255 e in experimental and clinical neuroscience, at present there is no systematic method to predict whic
256                                              At present, there are few studies that address health di
257                                              At present, there are few technologies which enable the
258                                              At present, there are many methods to evaluate the 3D re
259 V intake on mental health is less clear and, at present, there are no clear data to support a prefere
260                                              At present, there are no disease-modifying therapies to
261                                              At present, there are no effective approaches to prevent
262                                              At present, there are no established surrogate endpoints
263                                              At present, there are no known clinical findings, immuno
264                                              At present, there are no objective data specifically exa
265                                              At present, there are no proven pharmacological treatmen
266                                              At present, there are no published reports focusing upon
267                                     However, at present, there are no selective small-molecule inhibi
268                                              At present, there are no set guidelines establishing cum
269                                              At present, there exists no tool that can specifically m
270                                              At present, there is a great interest in enology for yea
271                                              At present, there is a lack of understanding of the comb
272                                              At present, there is a lack of well-validated protocols
273                                              At present, there is an ongoing effort to develop method
274                                              At present, there is limited understanding of the infect
275                                     However, at present, there is no consensus on the best method to
276                                              At present, there is no consensus regarding whether neut
277                                              At present, there is no cure or treatment for food aller
278                             This means that, at present, there is no device that adapts to the anatom
279                                              At present, there is no reliable noninvasive method to d
280                                              At present, there is no specific antidote available in t
281                                              At present, there is no treatment that can prevent anest
282                                              At present, there is, however, insufficient evidence for
283                                              At present these 'trophic interaction modifications' are
284                                              At present, these penitentes deepen by approximately one
285       Pneumococcus has continued to decline; at present, this organism is identified in fewer than fe
286                                              At present, TNF is mainly detected by measuring the prec
287 der by raising a measured debate which seems at present to be missing within the profession.
288 d to be considerably more sophisticated than at present to capture the full deep-sea habitat heteroge
289                                              At present, treatment mainly consists of antipsychotic d
290 r the majority of A-to-I editing events are, at present, uncertain.
291 o exacerbated neuronal activity during HF is at present unknown.
292                   The highest efficiency OPV at present use low-bandgap donor polymers, many of which
293                                              At present, VCA is an emerging field with a small number
294  organic linkers, and functional groups, but at present we do not have a formalism to quantify optima
295                                              At present we do not know if published reports of guidel
296 or understanding visual system organisation, at present we know very little about the basic visual re
297                                              At present, we have little understanding of the mechanis
298                                        Thus, at present, we recommend that existing outcome measures,
299                              It is not known at present whether neuronal cell-type diversity-defined
300 cure, thousands of individuals who are alive at present will succumb to the disease.

 
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