ライフサイエンスコーパス: atomic resolution

1 ted to the investigation of this behavior at atomic resolution.

2 has resolved many of these complexes to near-atomic resolution.

3 of other complex biological machines to near-atomic resolution.

4 lex and solved its cryo-EM structure to near-atomic resolution.

5 four dimensions (that is, including time) at atomic resolution.

6 depth view of these ever-elusive proteins at atomic resolution.

7 nemal dynein MTBDs bind microtubules at near atomic resolution.

8 ne to determine structures of molecules with atomic resolution.

9 in the presence or absence of drugs at near-atomic resolution.

10 ounds, metabolites, and biomacromolecules at atomic resolution.

11 nese-based ferromagnetic kagome lattice with atomic resolution.

12 ecular interface remain poorly understood at atomic resolution.

13 eikastus rhodopsin 2 (KR2), was resolved at atomic resolution.

14 n only if the protein structure is solved to atomic resolution.

15 peptide-activated GLP-1R-Gs complex at near atomic resolution.

16 INSTIs dolutegravir and bictegravir at near-atomic resolution.

17 not been tested in controlled experiments at atomic resolution.

18 pre-catalytic B complex spliceosome at near-atomic resolution.

19 an antibodies have not been characterized at atomic resolution.

20 FIN219-FIP1 while binding with substrates at atomic resolution.

21 termined by cryo-electron microscopy at near-atomic resolution.

22 r structure, kinetics, and thermodynamics at atomic resolution.

23 ponding spectra, which can be interpreted at atomic resolution.

24 systems with back action can be studied with atomic resolution.

25 se dimer by electron cryo-microscopy at near-atomic resolution.

26 ture and surface termination of the NCs with atomic resolution.

27 mer --> dimer --> membrane pore formation at atomic resolution.

28 ctural and dynamic description of CBP-ID4 at atomic resolution.

29 cleotide-driven structural changes in p97 at atomic resolution.

30 nal methods to describe non-native states at atomic resolution.

31 c investigation of restructuring dynamics at atomic resolution.

32 he molecular basis of Alzheimer's disease at atomic resolution.

33 ructures of Msp1-substrate complexes at near-atomic resolution.

34 gnal transduction in the cGAS pathway at the atomic resolution.

35 mplex DNA origami object to be determined to atomic resolution.

36 neous pore assembly for the AMP maculatin at atomic resolution.

37 spectroscopic tool to explore molecules with atomic resolution.

38 eraction site of ligand-protein complexes at atomic resolution.

39 sed to determine the amyloid-CR interface at atomic resolution.

40 ely paints a picture of STING signaling with atomic resolution.

41 structure-activity correlation studies with atomic resolution.

42 cent advances in this field have allowed for atomic resolution.

43 ture of AtERF96 in complex with a GCC box at atomic resolution.

44 ring mineral/protein crystalline assembly at atomic resolution.

45 hysiological intracellular environment at an atomic resolution.

46 ain three-dimensional structures approaching atomic resolution.

47 both RyR1 and RyR2 have been solved at near-atomic resolution.

48 s have had their structures characterized at atomic resolution.

49 to be developed that provide information at atomic resolution.

50 gain structural and functional insights with atomic resolution.

51 nergetics and dynamics of the interaction at atomic resolution.

52 isiae SWI/SNF bound to a nucleosome, at near-atomic resolution.

53 s-domain disulfide bonds, also visualized at atomic resolution.

54 ion in nanoscale and biological systems with atomic resolution.

55 surface reconstruction with four-dimensional atomic resolution.

56 in complex with cyclophilin A (CypA) at near-atomic resolutions.

57 t exciting macromolecular assemblies at near-atomic resolution (3-4.5A), providing biological phenome

58 Here, we present the near atomic resolution (3.2 angstrom) cryo-EM structure of ye

59 olloidal platinum nanocrystals by developing atomic-resolution 3D liquid-cell electron microscopy to

60 plicative helicases at a replication fork at atomic resolution, a prerequisite to understanding the u

61 m and reconstructed 3D chemical maps at near-atomic resolution acquired from APT reveals the core con

62 efined macromolecular synthesis with perfect atomic resolution across three-dimensional space that se

63 Structures are often represented at atomic resolution, although ad hoc simplified representa

64 U1 sub-structures, which together reveal at atomic resolution an almost complete network of protein-

65 l electronic structure of ScB(2) C(2) at sub-atomic resolution and allows for an unequivocal identifi

66 diffraction from aligned molecules provides atomic resolution and allows for the retrieval of struct

67 states by atomic force microscopy, obtaining atomic resolution and bond-order discrimination using ca

68 In silico molecular modeling using atomic resolution and coarse-grained simulations corrobo

69 w being used to determine structures at near-atomic resolution and have great promise in molecular ph

70 n by cryo-electron microscopy has approached atomic resolution and helped solve structures of large m

71 the cryo-EM structure of mature JEV at near-atomic resolution and identify structural elements that

72 mage the kagome structure with unprecedented atomic resolution and observe the striking bosonic mode

73 oscopy to map the I942-EPAC1 interactions at atomic resolution and propose a mechanism for I942 parti

74 as played a major role given its unique near-atomic resolution and sensitivity to the dynamics that u

75 and Zika virus) particles are known to near-atomic resolution and show detailed structure and arrang

76 One can now see ligands with atomic resolution and understand their behavior on the s

77 NMR is a powerful technique to obtain atomic-resolution and dynamic details of a protein in so

78 tinct needle assembly states, including near-atomic resolution, and local reconstructions in the abse

79 ependency of the intensities associated with atomic-resolution annular dark field imaging line scans

80 ds for probing protein-protein interfaces at atomic resolution are highly desirable.

81 Although structures determined at near-atomic resolution are now routinely reported by cryo-ele

82 -26.7% and improved mean MOLPROBITY score to atomic resolution at 1.25 A (100th percentile).

83 We were able to determine the atomic-resolution backbone conformation of an antigenic

84 uctures of overlapping ECD fragments at near atomic resolution, built a model of the full ECD, and di

85 Scanning probe techniques provide atomic resolution, but are limited to observations of sl

86 alpha bound to phosphorylated Ric-8A at near atomic resolution by cryo-electron microscopy and X-ray

87 of the 80alpha and SaPI1 procapsids to near-atomic resolution by cryo-electron microscopy, and show

88 (TE) factor during protein synthesis at near-atomic resolution by cryoelectron microscopy (cryo-EM).

89 ion, we mapped the HSA-Abeta interactions at atomic resolution by examining the effects of HSA on Abe

90 ify and localize biomolecular frustration at atomic resolution by examining the statistics of the ene

91 This isomerization has been characterized at atomic resolution by quantitatively interconverting the

92 roscope (STEM) has emerged as a key tool for atomic resolution characterization of materials, allowin

93 reported here establishes the foundation for atomic-resolution characterization of a broad range of a

94 Here we use atomic-resolution chemical mapping to reveal the element

95 Our results provide an atomic resolution cryo-EM structure of a nucleosome and

96 Here we present near-atomic resolution cryo-EM structures for flagellar filam

97 Here the authors present near-atomic resolution cryo-EM structures of nine flagellar f

98 Here we report near-atomic resolution cryo-EM structures of the bacteriophag

99 Here, we report near-atomic resolution cryo-EM structures, at resolutions ran

100 structural proteomics approach whereby near-atomic-resolution cryo electron microscopy (cryoEM) maps

101 le protein structure determination from near-atomic-resolution cryo-electron microscopy (cryo-EM) map

102 Here we present near-atomic-resolution cryo-electron microscopy structures fo

103 ls in models that are manually built in near-atomic-resolution cryo-EM maps.

104 Using near-atomic resolution cryoEM reconstruction and single filam

105 (2020a) present near-atomic resolution cryoEM structures of a proton-pumping

106 Here, we report the near-atomic resolution cryoEM structures of the Escherichia c

107 The atomic resolution crystal structure of C69G-GES-5 shows

108 uctural basis for this stabilization with an atomic resolution crystal structure of collagen containi

109 uctural basis for this stabilization with an atomic resolution crystal structure.

110 Here we report atomic-resolution crystal structures of Ca(2+)- and Mg(2

111 Structural studies have now provided atomic-resolution crystal structures of most nucleoporin

112 Here we report atomic-resolution crystal structures of three such compo

113 terize these dynamic structures by combining atomic-resolution crystal structures with lower-resoluti

114 Here, we present the atomic resolution crystallographic structure, the functi

115 minescent material which has been studied by atomic-resolution Cs -corrected STEM.

116 The atomic resolution description of long-range and local st

117 etermined at 2.2-A resolution and provide an atomic-resolution description of the architecture of its

118 apabilities of the methodology for obtaining atomic-resolution descriptions of dynamic systems.

119 cular dynamics simulations can provide novel atomic resolution details regarding mechanostability and

120 erimental data and theory for characterizing atomic-resolution dynamics in biological systems.

121 Here we determined the atomic resolution electron cryo-microscopy (cryo-EM) str

122 l termination of the M1 crystals, as seen by atomic resolution electron microscopy, exposing a high c

123 e the reactors during the meltdowns based on atomic-resolution electron microscopy of CsMPs discovere

124 Atomic-resolution electron microscopy studies clearly id

125 In this work, using atomic-resolution electron microscopy, we resolve the ba

126 ) which can be characterized incisively with atomic-resolution electron microscopy, X-ray absorption

127 loops, i.e., SALTs, are found ubiquitous by atomic-resolution electron microscopy.

128 While electron microscopes can now provide atomic resolution, electron beam induced specimen damage

129 nformers by cryo electron microscopy to near-atomic resolution, elucidating the molecular basis of he

130 ty to image light elements in soft matter at atomic resolution enables unprecedented insight into the

131 Atomic resolution energy dispersive X-ray spectroscopy r

132 -defined hydrocarbon binding pocket provides atomic resolution evidence for the extended lipid anchor

133 tunnelling maps of spin-resolved states with atomic resolution, finding interference processes from w

134 By reaching near-atomic resolution for a wide range of specimens, single-

135 f directly obtaining structural data at near-atomic resolution, for many molecules the attainable res

136 Atomic-resolution high angle annular dark field scanning

137 Here, we establish at atomic resolution how T-STAR and Sam68 bind to RNA, reve

138 It has not been observed at the atomic resolution how the polymerase advances one nucleo

139 Two types of prevalent planar defects from atomic resolution imaging are observed: previously unrep

140 Using atomic-resolution imaging and electron spectroscopy, the

141 Atomic-resolution imaging in an aberration-corrected sca

142 Atomic-resolution imaging of the Ir centers and spectra

143 bles the detection of single metal atoms and atomic-resolution imaging of the iron core of ferritin m

144 Atomic-resolution imaging reveals the coexistence of two

145 Here, the authors use atomic-resolution imaging to demonstrate facet dependent

146 olayer amorphous carbon can be determined by atomic-resolution imaging.

147 n nanotube one-by-one has been achieved with atomic resolution in real time, revealing key stages of

148 Finally, we present a near-atomic resolution in situ structure of the complete S-la

149 for activated CDTb (1.0 MDa) were solved at atomic resolution, including a symmetric ((Sym)CDTb; 3.1

150 etics and equilibria of chemical exchange at atomic resolution, including relaxation dispersion, exch

151 While NMR provides structural information at atomic resolution, increased spectral complexity, chemic

152 exemplify the uniqueness of NMR in providing atomic resolution information into key dynamic processes

153 NMR spectroscopy is able to provide atomic-resolution information for ribosome-nascent chain

154 To date, no atomic-resolution information on peptide-TAP interaction

155 discovery benefits immensely from access to atomic-resolution information, structure-based virtual s

156 Our results provide atomic resolution insight into how a small molecule bind

157 se molecular dynamics simulations to provide atomic-resolution insight into the influence of choleste

158 Although the number of atomic-resolution insights into contractile bacteriophag

159 -state NMR is a powerful technique to obtain atomic-resolution insights into the structure and dynami

160 of electron microscopic investigations with atomic resolution into the third dimension.

161 deling of chemical and biological systems at atomic resolution is a crucial tool in the chemist's too

162 ing the process of oxygen ion migration with atomic resolution is highly desirable for designing nove

163 ion of cryo-EM structures to the point where atomic resolution is now achievable.

164 At atomic resolution, it becomes possible to extend frustra

165 Here we use atomic-resolution Josephson scanning tunnelling microsco

166 ent strategy to inactivate TNFalpha, but the atomic-resolution mechanism of its inactivation remains

167 lly exfoliated samples, as confirmed by both atomic resolution microscopic imaging and electrical tra

168 olecular dynamics simulations, we present an atomic resolution model of human RNF169 binding to a ubi

169 ectron microscopy (cryo-EM), we establish an atomic resolution model of the RSV CA tubular assembly u

170 Finally, it provides an atomic-resolution model of the primary neutralizing anti

171 These atomic resolution models capable of explaining the obser

172 enic analysis, guided by homology mapping in atomic resolution models of Kir2.1, Kir2.3, and Kir4.1/5

173 We construct atomic resolution models of thousands of candidate subst

174 ctures will contribute to the development of atomic-resolution models of the entire sorting platform

175 Guided by atomic-resolution models, we develop fusions of Src homo

176 These atomic-resolution observations offer a basis for rationa

177 in complex with cognate DNA at an ultra-high atomic resolution of 1.0 angstrom.

178 structure for the apo form of AgmNAT with an atomic resolution of 2.3 A, which points towards specifi

179 cryo-electron microscopy structures at near-atomic resolution of Hsp104 in different translocation s

180 croscopy (SP-cryo-EM) routinely reaches near-atomic resolution of isolated complexes.

181 methods to determine the structures at near-atomic resolution of the influenza hemagglutinin trimer,

182 We report the direct observation, at atomic resolution, of surface melting in individual size

183 of the HK signal transduction mechanism with atomic resolution on a full-length construct lacking onl

184 State-of-the-art atomic resolution or in situ scanning transmission elect

185 Here we review recent atomic-resolution or near-atomic resolution structures o

186 or such studies, seamlessly integrating near-atomic resolution protein structures, organism-scale arc

187 A combination of atomic-resolution protein X-ray crystallographic structu

188 by subsequent enzyme kinetic studies; their atomic-resolution quality provides the basis for future

189 ation of such transient weak interactions at atomic resolution remains challenging.

190 ophila melanogaster at subnanometer and near-atomic resolution, respectively.

191 eling to define doublet microtubules at near-atomic resolution, revealing an intricate array of prote

192 d the potential to make the determination of atomic-resolution RNA ensembles routine.

193 Further investigation with atomic resolution scanning transmission electron microsc

194 rforming in situ annealing experiments in an atomic resolution scanning transmission electron microsc

195 nature and composition of this material with atomic resolution scanning transmission electron microsc

196 d investigated with electron diffraction and atomic resolution scanning transmission electron microsc

197 Atomic resolution scanning transmission electron microsc

198 With atomic resolution scanning transmission electron microsc

199 ly weak superstructure phenomena revealed by atomic-resolution scanning TEM (STEM) and single-crystal

200 Atomic-resolution scanning transmission electron microsc

201 and is corroborated by aberration-corrected atomic-resolution scanning transmission electron microsc

202 Atomic-resolution scanning transmission electron microsc

203 Atomic-resolution scanning transmission electron microsc

204 Transmission electron microscopy (TEM) and atomic-resolution scanning transmission electron microsc

205 rontium titanate layers, which are imaged by atomic-resolution scanning transmission electron microsc

206 being conveniently integrated with existing atomic resolution sensors, the heterostructure platform

207 rful tool for studying molecular dynamics at atomic resolution simultaneously for a large number of n

208 isition with a phase plate that enables near-atomic resolution single particle reconstructions.

209 our experiments using X-ray diffraction and atomic resolution STEM-HAADF electron microscopy.

210 Compared with conventional atomic-resolution STEM imaging techniques, the mixed-sta

211 NMR represents a unique tool to access atomic resolution structural and dynamic information on

212 e, adequate methodologies reliably providing atomic resolution structural details are still lacking.

213 lar couplings (RDCs) are highly valuable for atomic-resolution structural and dynamic studies of mole

214 -modification sites that are consistent with atomic-resolution structural data.

215 ight some of the latest studies that provide atomic-resolution structural details imperative for the

216 approach uses multiple-sequence alignments, atomic-resolution structural information, and riboswitch

217 Our near-atomic resolution structure clearly shows that SpoIIIAG

218 uman NgBR/DHDDS complex, which represents an atomic resolution structure for any heterodimeric cis-PT

219 e and structural heterogeneity, attaining an atomic resolution structure is challenging, but importan

220 ctron microscopy, here we determine the near-atomic resolution structure of a human APC/C-MCC complex

221 Here, we present an atomic resolution structure of a monomorphic form of Abe

222 In this study, we report the first atomic resolution structure of a stable G-hairpin formed

223 This work presents the atomic resolution structure of AdhE and suggests that th

224 use of the transient subunit association, an atomic resolution structure of an active alpha2beta2 RNR

225 With recent technological advances, the atomic resolution structure of any purified biomolecular

226 DNA to 2.3 A resolution providing the first atomic resolution structure of any TIA protein RRM in co

227 Our near-atomic resolution structure of CVA6 A-particle complexed

228 Here, we solved the atomic resolution structure of helical MAVS(CARD) filame

229 We provide the first atomic resolution structure of METTL5-TRMT112, supportin

230 Here, we present the near-atomic resolution structure of one of these proteins, Sp

231 Here, we describe the near-atomic resolution structure of the phi6 double-shelled p

232 The atomic resolution structure reveals a DotLMNYZ hetero-pe

233 We expect the technique to pave the way for atomic-resolution structure analysis applicable to a wid

234 Atomic-resolution structure determination is crucial for

235 izes into filaments, but there is not yet an atomic-resolution structure of a calsequestrin filament.

236 Here, we report the atomic-resolution structure of capsid protein (CA) tubes

237 Here we use solid-state NMR to determine the atomic-resolution structure of fibrils of synthetic huma

238 ving Cys367 in keratin 14 (K14) occurs in an atomic-resolution structure of the interacting K5/K14 2B

239 ay/neutron (XN) crystallography to obtain an atomic-resolution structure of the protease triple mutan

240 This report describes the atomic-resolution structure of the spike protein from po

241 sic biophysical studies and for which a near-atomic-resolution structure or homology model is availab

242 an X-ray free-electron laser, leading to an atomic-resolution structure with accurate rotamer assign

243 An abundance of atomic resolution structures and complementary biochemic

244 EM) are enabling generation of numerous near-atomic resolution structures for well-ordered protein co

245 systems, new methods are required to obtain atomic resolution structures from biological material un

246 Here, we determine the atomic resolution structures of dimeric, tetrameric, and

247 Specifically, it benefits the study of atomic resolution structures of large membrane protein c

248 e we review recent atomic-resolution or near-atomic resolution structures of NSF and of the 20S super

249 come one of the most powerful techniques for atomic resolution structures of protein fibrils.

250 Here we review how combining atomic resolution structures of smaller domains with spa

251 Atomic resolution structures of the apo- and holo-forms

252 tron microscropy (cryo-EM) to determine near-atomic resolution structures of the human PIC in a close

253 uence-dependent nuclear factors require near-atomic resolution structures of the nucleosome core cont

254 chanism of cycloaddition, we have determined atomic resolution structures of the pyridine synthases i

255 that infect many eukaryotic hosts, the near-atomic resolution structures of these viruses have remai

256 Recent atomic or near-atomic resolution structures of three physiologically si

257 We present the first atomic resolution structures of three such replication p

258 Here, we report near-atomic resolution structures of two NS1 tubular forms de

259 The recent near-atomic resolution structures revealed that the interlaci

260 Because of the current lack of atomic-resolution structures for plant CSCs or CESAs, th

261 n microscopy a key technique to achieve near-atomic-resolution structures of biochemically isolated m

262 Atomic-resolution structures of four VHP analogues were

263 Here we present near-atomic-resolution structures of human and frog PANX1 det

264 icle reconstruction, we have determined near-atomic-resolution structures of the EBV capsid with an a

265 Our studies provide atomic-resolution structures of the PP-IP products and u

266 stablished a robust protocol for determining atomic-resolution structures of TM oligomers by NMR in b

267 High- to atomic-resolution structures reveal the structural eleme

268 persion of the parameters from a database of atomic-resolution structures.

269 ctions requires detailed maps in the form of atomic-resolution structures.

270 of SH3 domains requires detailed structural, atomic-resolution studies along with biochemical and bio

271 Atomic-resolution studies for these molecules are essent

272 antly reduced this size limitation, enabling atomic-resolution studies of molecular machines in the 1

273 Methyl-NMR enables atomic-resolution studies of structure and dynamics of l

274 ocused on the development of experiments for atomic-resolution studies of these molecules.

275 nvestigate protein conformational changes at atomic resolution, such as those changes induced by drug

276 rmore, for the first time, we demonstrate at atomic resolution that the flip of a peptide plane from

277 ive state (C/O), this work recapitulates, at atomic resolution, the key conformational changes of a p

278 3) superlattices to directly determine, with atomic resolution, the local regions in the ferroelectri

279 Here, using atomic-resolution, time-resolved in-situ environmental t

280 t the X-ray crystal structure of ProTx-II to atomic resolution; to our knowledge this is the first cr

281 Atomic resolution transmission electron microscopy was u

282 lm via in situ ion irradiation studied using atomic-resolution transmission electron microscopy (TEM)

283 Here we use atomic-resolution transmission electron microscopy to re

284 Atomic-resolution transmission electron microscopy was u

285 nanoparticles has been limited by less than atomic resolution typically achieved by environmental tr

286 thods for characterizing such transitions at atomic resolution under solution conditions.

287 c potential of a two-dimensional material at atomic resolution under various low dose conditions.

288 psid structures of these clinical vectors at atomic resolution using cryo-electron microscopy and ima

289 ral major capsid protein, elucidated at near-atomic resolution using cryo-electron microscopy, is str

290 amples can now be routinely analyzed at near-atomic resolution using standard imaging and image analy

291 olution reconstruction that offers a genuine atomic-resolution view of a protein molecule using singl

292 c electron microscopy(9), we report the near-atomic-resolution view of how a time-ordered series of c

293 intermediate filament assembly mechanisms at atomic resolution, we determined the crystal structure o

294 ii Determining the Anf3 crystal structure to atomic resolution, we observed that it is a dimeric flav

295 ral information of diverse materials down to atomic resolution, which is essential for figuring out t

296 ultilayer structural details of ASFV at near-atomic resolution, which provides interesting insights a

297 f mature Japanese encephalitis virus at near-atomic resolution, which reveals an unusual "hole" on th

298 enforcing symmetry facilitates reaching near-atomic resolution with fewer particle images, it unfortu

299 ing transmission electron microscopy (STEM), atomic resolution with picometer precision cannot usuall

300 (STEM) provides structure and composition at atomic resolution, with the sensitivity to directly reve