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1 luster edges, implying tetramer formation is autocatalytic.
2 ee energy barrier of 36.1 kcal/mol and to be autocatalytic.
3 ndicating that the covalent flavinylation is autocatalytic.
5 nts of axon/dendrite formation involve local autocatalytic activation and long-range inhibition, as p
6 eparate but interacting feedback mechanisms (autocatalytic activation and substrate depletion) are ca
7 cells to generate metabolic oscillations via autocatalytic activation by its product fructose 1,6-bis
8 he PC7 precursor protein undergoes efficient autocatalytic activation in both oocytes and embryos.
14 1 is approximately 3000-fold higher, and the autocatalytic activation of MASP-1 is about 140-fold fas
17 signal of bioanalytical assays based on the autocatalytic activation of these mutated proenzymes.
19 enzyme molecule of the same protease, and 2) autocatalytic activation, when the activated protease cl
21 as an excitable system in which a diffusive, autocatalytic activator causes actin polymerization; F-a
23 onstitutively active enzyme, with high basal autocatalytic activity and high basal activity toward pe
24 atalytic domain) display high basal Ser(916) autocatalytic activity and robust activity toward CREBti
25 tion requires ATG7 as the E1 enzyme and ATG3 autocatalytic activity as the E2, resulting in the coval
26 of ADAMTS17 requires O-fucosylation and its autocatalytic activity does not depend on propeptide pro
27 available for several classes of enzymes and autocatalytic activity encoded by nonenveloped viruses.
31 he inflammasome results in initiation of its autocatalytic activity, culminating in self-cleavage tha
32 ty paradigm, which appears to be general for autocatalytic additions to heme prosthetic groups, sugge
33 lar particle agglomeration, B + B --> C, and autocatalytic agglomeration, B + C --> 1.5C, involved in
35 pand on our previous discovery of iterative, autocatalytic alpha- N-methylating precursor proteins in
38 self-assembles into nanostructures, coupling autocatalytic and assembly pathways to realize a reprodu
41 However, those reactions with aniline were autocatalytic and had significant induction periods ( ap
43 ities of the two-segment compound enable the autocatalytic, and in general ROS-mediated, activation o
44 nd serve as mother filaments to initiate the autocatalytic assembly of the branched actin filament ne
45 e; however, it remains to be seen whether an autocatalytic-based drug delivery system has an advantag
46 ysts have been previously reported, coupling autocatalytic behavior to macromolecular self-assembly h
49 sible chemical and physical stimuli, and the autocatalytic behaviours within DCLs which can result in
50 to build a network of organic reactions with autocatalytic, bistable and oscillatory behaviour, we id
53 nmol/min for 2 min or more, which sets up an autocatalytic cascade triggered by activating type 2 nit
57 en involves large conformational changes and autocatalytic chemistry that can be hampered by small mo
59 ondrial processing peptidase and Oct1 and an autocatalytic cleavage at a highly conserved LGST motif
62 sitol-linked protein and undergoes a partial autocatalytic cleavage during its intracellular processi
63 in GPCR proteolytic site motifs that undergo autocatalytic cleavage during receptor processing to cre
66 s serine proteinase activity and can undergo autocatalytic cleavage liberating distinct fragments.
67 wn protein fold and a functionally important autocatalytic cleavage mechanism and provides a framewor
68 tivation of the AIM2 inflammasome results in autocatalytic cleavage of caspase-1, resulting in the pr
71 inositol hexakisphosphate (InsP6) induces an autocatalytic cleavage of the toxins, releasing an N-ter
73 dimension between pH 5.5 and 5 requires the autocatalytic cleavage to achieve its final compact size
74 tide precursor that undergoes intramolecular autocatalytic cleavage to generate a fully active hetero
77 e 226 on delta-secretase and accelerates its autocatalytic cleavage, leading to its cytoplasmic trans
79 ssion disrupts prohormone convertase 2 (PC2) autocatalytic cleavage, processing of secretogranin II t
81 dgehog (hh) encodes a protein that undergoes autocatalytic cleavage, releasing a signaling molecule i
83 ngle polypeptide (propeptide) that undergoes autocatalytic cleavage, which results in the formation o
88 ition molecule in the immune system, driving autocatalytic complement cascade activation and acting a
89 rification of the pyromellitate system under autocatalytic conditions; minor ester exchange with pre-
90 ure of Pb matches previous models, including autocatalytic conversion of phycocyanobilin to phycoviol
93 ovided by supramolecular ordering enables an autocatalytic cycle favouring the growth of DNA chains,
95 tween three subcomponents of the network: an autocatalytic cycle that generates thiols and amides fro
96 hypercycle defines the simplest model of an autocatalytic cycle, providing major theoretical insight
100 tworks are competed directly against selfish autocatalytic cycles, the former grow faster, indicating
102 echanism whereby interphase cells can oppose autocatalytic cyclin E degradation and maintain cyclin E
104 ncomplete glycosylation stimulates extensive autocatalytic degradation and self-inactivation of MT1-M
105 e results we propose that TIR1 is subject to autocatalytic degradation when assembled into an SCF.
106 RING ubiquitin ligases (CRL) by limiting the autocatalytic destruction of substrate adapters such as
108 : catalytic formation of branched junctions, autocatalytic duplex formation by a cross-catalytic circ
114 er mild conditions by using the output of an autocatalytic enzyme reaction to drive both the polymeri
117 such spatial patterns can form when a local autocatalytic feedback loop and a long-range inhibitory
119 d RFP (cpRFP) scaffold, which maintained its autocatalytic fluorescence, from a red fluorescent Ca(2+
121 ormation and provide a working model for the autocatalytic formation of protocells from the coupling
124 (2)), and hydrogen peroxide (H(2)O(2)) in an autocatalytic free radical chain reaction, which could p
126 it is often claimed that self-sustaining or autocatalytic front propagation is well described by mea
131 eation (A --> B, rate constant k 1) and fast autocatalytic growth (A + B --> 2B, rate constant k 2),
132 r nucleation (A --> B, rate constant k1) and autocatalytic growth (A + B --> 2B, rate constant k2), w
133 meration (B + B --> C) and secondary surface autocatalytic growth (A + C --> 1.5C) involved in suppor
134 The use of the F-W 2-step nucleation and autocatalytic growth kinetic model to fit 3 literature e
135 een used to infer the presence or absence of autocatalytic growth processes such as fibril fragmentat
139 dialkyl disulfides; a trigger that controls autocatalytic growth; and inhibitory processes that remo
140 tween the T7 RNA polymerase promoter and the autocatalytic hepatitis delta virus ribozyme of a transc
141 ns between phenomena generally attributed to autocatalytic hydrolysis and mass transfer limitation ef
142 om chains grow more informational and become autocatalytic (i.e., increasing their own concentrations
145 ht differentiates this protein splicing from autocatalytic inteins, and may allow the chloroplast to
148 unds act as acid amplifiers and decompose by autocatalytic kinetics to generate fluorinated sulfonic
149 or selective surfactant formation as well as autocatalytic kinetics; indeed, no selection is observed
150 honetria parasitica, encodes two papain-like autocatalytic leader proteases, p29 and p48, that also h
151 OH(cat.)/AcCl system was found to promote an autocatalytic-like condensation and facilitate the multi
152 h ordering and condensation would provide an autocatalytic link whereby complementarity promotes the
156 ectivity of flock house virus (FHV) requires autocatalytic maturation cleavage of the capsid protein
157 ion (TFR)-PR-FLAG, also undergoes N-terminal autocatalytic maturation when it is expressed in Escheri
158 at Dia2 protein turnover does not involve an autocatalytic mechanism and that Dia2 proteolysis is inh
160 ivation of its E3 ligase activity through an autocatalytic mechanism that amplifies its E3 ligase act
161 stem reveals a new, enzyme-free, isothermal, autocatalytic mechanism that introduces means for effect
167 ility of such networks, which depends on the autocatalytic motifs they contain and is notably increas
168 PR/Cas9 genome-editing system for generating autocatalytic mutations, to produce homozygous loss-of-f
169 oduces a molten silica shell that acts as an autocatalytic 'nanoreactor' by actively transporting oxy
170 ar, our results show that the characteristic autocatalytic nature of the growth process originates fr
171 stochastic model confirms the presence of an autocatalytic network involving molecular recognition an
172 able to catalyze their own formation via an autocatalytic network, which subsequently template the a
176 f short, unstable microtubules maintained by autocatalytic nucleation and provide a paradigm for the
177 e rate at the adjacent two amides, often the autocatalytic nucleophiles in deamidation, correlated wi
183 Here, we demonstrate an interaction between autocatalytic PCD and lytic viral infection in the cosmo
184 ecombinant protein allowed monitoring of the autocatalytic peroxide-driven formation of covalent heme
185 e targets for a protein kinase C-independent autocatalytic phosphorylation and that the PKD1-S744A/S7
191 taneous [Ca(2+)](i) peaks may result from an autocatalytic process and that [Ca(2+)](i) oscillation i
193 uantitative understanding and control of the autocatalytic process involved in the synthesis of collo
196 vo from purified native PrPC molecules in an autocatalytic process requiring accessory polyanions.
197 endogenous ROS production in a regenerative, autocatalytic process that ultimately results in global
198 dal metal nanocrystals typically involves an autocatalytic process, in which the salt precursor adsor
203 Theoretical models have long suggested that autocatalytic processes can result in kinetically contro
204 the 44-kDa form of MT1-MMP generated during autocatalytic processing in maintaining the pool of acti
208 activation of SKI-1/S1P involves sequential autocatalytic processing of its N-terminal prodomain at
209 arked retardation of the in vitro N-terminal autocatalytic processing of TFR-PR(H69E) and suggesting
210 e dispensable for hypovirus replication, the autocatalytic processing of the leader proteases p29 and
211 ble from fully glycosylated TPP1 in terms of autocatalytic processing of the proform and enzymatic pr
212 icated that the p.G178R mutation impairs the autocatalytic processing of this enzyme resulting in the
213 ivity is revealed by maturation following an autocatalytic processing resulting in the cleavage of bo
214 ome catalytically active, Psd1p undergoes an autocatalytic processing step involving a conserved LGST
215 60-kDa inactive precursor that must undergo autocatalytic processing to generate a 40-kDa/20-kDa het
218 of the coupling between the enzyme-catalyzed autocatalytic production and diffusion of hydrogen ions.
219 pagation saturates, leading to a switch from autocatalytic production of infectivity (phase 1) to a t
222 whereas monomeric alpha-synuclein blocks the autocatalytic proliferation of Abeta42 (the 42-residue f
223 concentrations, the interaction inhibits the autocatalytic proliferation of amyloid fibrils by second
227 inducible signals that might accelerate its autocatalytic properties and dictate where inflammasome
229 As a key prediction of a model integrating autocatalytic protein aggregation and a minimal Start ne
232 ith oxyhemoglobin, and although this complex autocatalytic reaction has been studied for a century, t
235 rk reveals how kinetics of a phase-separated autocatalytic reaction may be used to control the popula
236 we use experimental data from the model Soai autocatalytic reaction system to evaluate the energy req
237 outcome of both biological and nonbiological autocatalytic reaction systems that display a threshold
238 of apoMSOX has been shown to proceed via an autocatalytic reaction that requires only FAD and is blo
240 mutants by active alpha-thrombin triggers an autocatalytic reaction which leads to more active thromb
245 r restricted the diffusion of copper and the autocatalytic reduction limited the probability for seco
246 reduction of Ag(+) to form seeds followed by autocatalytic reduction of Ag(+) by ethylene glycol (and
247 y a nucleation-and-growth scenario involving autocatalytic reduction of the copper phyllosilicate fol
248 uniform size of precursor particles and the autocatalytic reduction thus offers means to synthesize
250 commitment requires efficient activation and autocatalytic release of caspase-8 into the cytoplasm to
251 C terminus is followed by an intramolecular autocatalytic removal of a 12-amino acid propeptide at t
252 plification (PMCA) technology to sustain the autocatalytic replication of infectious prions in vitro.
256 2) is a modifier in catalysis and acts in an autocatalytic role; there is a parallel, neutral catalys
257 toichiometrically inhibited both primary and autocatalytic secondary nucleation processes, even in th
258 nner mitochondrial membrane, must undergo an autocatalytic self-processing event to gain activity.
259 vities operating orthogonal from each other: autocatalytic self-replication of oligomers from native
260 Such foldamer catalysts are shown to form an autocatalytic set, through which short chains grow into
261 simple inorganic salt can spontaneously form autocatalytic sets of replicating inorganic molecules th
263 ral conformation of the glycosylasparaginase autocatalytic site without influence from any inhibitor
264 inding of glucosamine-6-phosphate stimulates autocatalytic site-specific cleavage near the 5' of the
265 chemical reaction of a light-sensitive acid autocatalytic solution in which the actuator is immersed
267 ulator of auxin signalling, and modulate the autocatalytic stabilization of auxin signalling output.
270 the prebiotic plausibility of each of these autocatalytic subsystems and combinations thereof: self-
271 of superenantiospecificity resulting from an autocatalytic surface explosion reaction of a chiral mol
272 be amplified by reaction mechanisms such as autocatalytic surface explosions which have nonlinear ki
273 -> B, rate constant k(1obs)), then (ii) fast autocatalytic surface growth (A + B --> 2B, rate constan
274 on (A --> B, rate constant k(1)) followed by autocatalytic surface growth (A + B --> 2B, rate constan
275 = 1.5(1.1) x 10(-3) h(-1)) followed by fast autocatalytic surface growth (A + B --> 2B, rate constan
276 2-step, slow continuous nucleation and then autocatalytic surface growth mechanism, A --> B (rate co
277 uous nucleation, A --> B (rate constant k1), autocatalytic surface growth, A + B --> 2B (rate constan
278 te constant k1), followed by typically fast, autocatalytic surface growth, A + B --> 2B (rate constan
279 + B --> C (rate constant k3), and secondary autocatalytic surface growth, A + C --> 1.5C (rate const
280 re we quantitatively analyze the kinetics of autocatalytic surface reduction in an effort to control
281 strate that the activation energy barrier to autocatalytic surface reduction is highly dependent on b
282 ation of cold-temperature exposure to induce autocatalytic system 2 ethylene biosynthesis and subsequ
283 to visualize the spontaneous emergence of an autocatalytic system from an aqueous mixture of two chem
286 t tomatoes was due to an inability to induce autocatalytic system-2 ET synthesis, a characteristic fe
288 ues into a cage allowed for the design of an autocatalytic system: oxidation of the methylthio groups
289 tanding the spatiotemporal dynamics of other autocatalytic systems and emphasize the relevance of clu
290 inetic investigations revealed key traits of autocatalytic systems including molecular recognition an
295 s framework extends the range of conceivable autocatalytic systems, by applying our stoichiometric an
296 , and it has no known function but undergoes autocatalytic truncations during purification and storag
297 Furthermore, degradation is regulated by the autocatalytic turnover of PUB22, which is stabilized upo
299 bonding picture is presented which predicts autocatalytic water dissociation to be a general phenome
300 f Cwp84, this cleavage does not appear to be autocatalytic, whereas in Cwp13 autocatalysis was demons