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1 l (HEV) infection in developed countries are autochthonous.
2 nstrate, however, that the deeply divergent, autochthonous African component which accounts for ~50%
5 ncy, and acidity-all important predictors of autochthonous and allochthonous primary production (PP):
6 ol from mango fruit (Mangifera indica L.) of autochthonous and Ataulfo varieties grown in Nayarit, us
7 er understanding of the faecal microbiota in autochthonous and commercial pigs, providing further ins
8 entify three to four independent lineages as autochthonous and likely founders: the major Q-M3 and ra
9 the separate data, distinguishing wines from autochthonous and nonautochthonous grapes, mono- from th
10 pared the efficacy of multiple approaches in autochthonous and s.c. transgenic adenocarcinoma of the
11 g interstitial fluid nutrient levels between autochthonous and transplant models of murine pancreatic
13 Our studies indicate that the biology of autochthonous and transplanted tumors is quite distinct.
14 response to prostate cancer, we developed an autochthonous animal model based on the transgenic adeno
15 ctor (BAFF)-R (BR3) through interaction with autochthonous B-lymphocyte stimulator (BLyS) ligand in D
19 haplogroup and Y-STR diversity of the three autochthonous Basque populations of Alava (n = 54), Guip
20 owed that extended control of advanced-stage autochthonous brain tumors is achieved following adoptiv
22 C in 3 SV40 large T (Tag)-driven conditional autochthonous cancer models with different immune status
24 stration of therapeutic IR to mice harboring autochthonous cancers reduced treatment toxicity without
26 of T. cruzi infection-the fifth reported US autochthonous case-would have been missed without his mo
30 s, such as in Louisiana and Texas, there are autochthonous cases of leprosy among native-born America
34 le of fermented musts from Prieto Picudo, an autochthonous Castilla y Leon (Spain) red grape variety
36 NTERPRETATION: Although the current risk for autochthonous CHIKV transmission in Canada is very low,
39 sterols, which can be used as biomarkers of autochthonous (cholesterol, cholestanol, brassicasterol,
43 aracterised Negroamaro red wines, made by an autochthonous cultivar of Southern Italy, by linking vol
45 ata are compatible with the hypothesis of an autochthonous development of the Minoan civilization by
48 ared to a bioaugmentation approach using the autochthonous Diaphorobacter polyhydroxybutyrativorans s
51 ty and quantity of overall allochthonous and autochthonous DOM as well as associated DBP formation ar
54 ity aliphatic and peptide-like components in autochthonous DOM, which could aid environmental assessm
55 Culture-confirmed cases were classified as autochthonous (domestically acquired) versus travel/immi
57 quatina lagoon (SE Italy) was compared to an autochthonous (Eriphia verrucosa) and to a commercial cr
58 ates, social science analysis has focused on autochthonous factors and paid less attention to the way
59 ome, with previous HE, relative abundance of autochthonous families decreased whereas potentially pat
60 are likely to be important sources of marine autochthonous FDOM, which may accumulate in the deep oce
61 olet absorbance at 254 nm (SUVA(254))), more autochthonous (fluorescence index), and more recently pr
62 h Onchocerca volvulus was investigated in an autochthonous focus caused by the migration of infected
63 generalists and those that directly exploit autochthonous food resources, did not vary significantly
66 eveloped an adeno-associated virus-mediated, autochthonous genetic CRISPR screen in glioblastoma.
67 a variety of sophisticated models, including autochthonous genetically engineered mice, orthotopic sy
68 phagy in prostate cancer, we generated a new autochthonous genetically engineered mouse model (GEMM)
72 study of various wines derived from rare and autochthonous grape varieties of north-western Italy.
75 elevated oxidation stress but also served as autochthonous H2O2 resource to trigger CPT release for c
76 a, is an anomaly with extreme frequencies of autochthonous haplogroups of Near Oceanian origin; simul
82 Here, we report images of centimeter-size, autochthonous hematite filaments that are pectinate-bran
84 be a case of acute liver injury caused by an autochthonous hepatitis E that resolved under steroid tr
85 rowth in multiple xenograft models and in an autochthonous, highly aggressive genetically engineered
86 this clinical scenario, we developed a novel autochthonous HPV-positive oral tumor model to track res
88 ollowed by varying degrees of admixture with autochthonous hunter-gatherers, and then substantial gen
89 dy tracks the course of MEKi treatment in an autochthonous imageable murine model of melanoma from in
90 llectively this provides a novel tunable and autochthonous immune response to extracellular HSPs whic
91 nt Repeat (MVR) analysis in a sample of >100 autochthonous individuals from the Basque Country, along
93 in vivo, prolongs survival in advanced-stage autochthonous KRAS(G12C)-driven pancreatic and lung tumo
94 performed for CSCs and fibroblast markers in autochthonous Kras(G12D/+); Trp53(R172H/+); Pdx1-Cre mic
95 ricted genetic ablation of murine TRAIL-R in autochthonous KRAS-driven models of non-small-cell lung
97 nufactured from milk with deliberately added autochthonous lactic acid bacteria (LAB) or commercial s
98 tudy investigated the capability of selected autochthonous lactic acid bacteria to enrich the portfol
99 through a designed fermentation by selected autochthonous Lactobacillus plantarum AFI5 and Lactobaci
102 n oil producers (NW Spain) in recovering old autochthonous Local olive fruits has increased substanti
104 itro and metastases analyzed ex vivo from an autochthonous lung cancer mouse model had lower mitochon
105 Here, we utilized both syngeneic and novel autochthonous lung tumor models in which neoplastic cell
106 genous p53 expression leads to regression of autochthonous lymphomas and sarcomas in mice without aff
108 Factors intrinsic to the mice that host the autochthonous mammary carcinomas were also not responsib
109 ed with chemotherapy to elicit regression of autochthonous mammary gland tumors in MMTV-Neu mice.
111 allografts generated from previously treated autochthonous medulloblastomas compared with those from
112 boost immunization could effectively prevent autochthonous melanoma in tumor-prone transgenic mice, p
113 iation, motility, and hyperplasia and, in an autochthonous melanoma model, results in increased tumor
124 cy, we adapted the Kras(LSL-G12D/+);p53(f/f) autochthonous model of lung adenocarcinoma to express th
125 Kras-induced tumorigenesis in vivo using an autochthonous model of lung adenocarcinoma with concomit
127 at RNA combination therapy is possible in an autochthonous model of lung cancer and provide preclinic
129 eate the natural history of metastasis in an autochthonous model of pancreatic ductal adenocarcinoma
132 a in the context of an oncogenic Kras-driven autochthonous model of PDAC, the authors demonstrated th
134 or tumor-promoting role of T reg cells in an autochthonous model of tumorigenesis, and they reveal th
135 uman cancers of a similar type, making these autochthonous model systems useful for additive engineer
136 To study T cell responses to tumors in an autochthonous model, we expressed a CD8 T cell epitope S
137 al interactions, in addition to confirmatory autochthonous models and/or genetically engineered model
138 This model expands the limited repertoire of autochthonous models of clinically aggressive thyroid ca
139 enty-two Macedonian red wines, including ten autochthonous monovarietal Vranec wines produced with di
141 ong-term persistence, capacity to infiltrate autochthonous mouse melanomas, thrive in their microenvi
143 or Bmi1 in intestinal tumorigenesis using an autochthonous mouse model in which Apc was conditionally
145 Here, we utilize a macrophage-dependent autochthonous mouse model of breast cancer to demonstrat
146 ing ecDNAs to promote tumour formation in an autochthonous mouse model of hepatocellular carcinoma.
147 ignificantly reduced tumor volume gain in an autochthonous mouse model of Kras(G12D) -driven soft tis
149 ical evidence that resistance to BRAFi in an autochthonous mouse model of melanoma is associated with
150 ses cell:cell repulsion and metastasis in an autochthonous mouse model of pancreatic adenocarcinoma-w
151 Here we adapted a genetically engineered, autochthonous mouse model of sarcomagenesis to investiga
153 om human tumors and a genetically engineered autochthonous mouse model of soft-tissue sarcomas (STSs)
155 n vivo functional screens using quantitative autochthonous mouse model systems to uncover the genetic
156 athered from human sarcoma patients, a novel autochthonous mouse model, and mechanistic analyses, we
159 ells, developing embryos, adult tissues, and autochthonous mouse models of human brain and lung cance
160 profile mitochondrial membrane potential in autochthonous mouse models of lung cancer, and find dist
161 rally controlled functional perturbations in autochthonous mouse models, we show that the combination
165 growth and progression of both syngeneic and autochthonous mouse prostate cancer models in an immunoc
167 also enhances tumor growth in implanted and autochthonous mouse tumor models with no detectable effe
168 man PDAC tissues with gemcitabine treatment, autochthonous mouse tumors from Kras(G12D); Pdx1-Cre (KC
169 r-1(+) cells from both implantable (4T1) and autochthonous (mouse mammary tumor virus-polyomavirus mi
171 d prominently inhibits tumour development in autochthonous murine KRAS-driven lung cancer models.
172 ed in the lung, in Kras(G12D/+);Trp53(fl/fl) autochthonous murine lung adenocarcinoma had no effect o
173 r pathology, we genetically ablated it in an autochthonous murine model (KrasG12D; Pdx-1cre, KC), whi
174 ze drug response in an inducible RAF-driven, autochthonous murine model of melanoma incorporating a f
177 n enzymatic agent can ablate stromal HA from autochthonous murine PDA, normalize IFP, and re-expand t
178 e examined the DNA methylation pathway in an autochthonous murine prostate cancer model, transgenic a
180 between the vasculature of transplanted and autochthonous murine tumors and indicate that their susc
182 ce, pharmacologic treatment of mice carrying autochthonous NSCLCs with a gamma-secretase inhibitor (G
185 oducers (NW Spain) in recovering the ancient autochthonous olive varieties Brava and Mansa has increa
186 9 genome editing and tumor barcoding with an autochthonous oncogenic KRAS-driven lung cancer model an
187 as seagrass beds, typically account only for autochthonous organic carbon, potentially underestimatin
190 different taxa over less than 200 km(2): the autochthonous P. perezi, along with the alien P. ridibun
191 ta to deconvolute multiple allochthonous and autochthonous pan-Arctic and watershed-specific sources.
193 e biologic mechanisms of SMO inhibition, two autochthonous pancreatic cancer models (Kras(G12D); p16/
196 dy indicate that the pig meat, in particular autochthonous pig meat, may be considered a functional f
197 highlighted that the pig meat, in particular autochthonous pig meat, showed good concentrations of en
199 gher than present, and resulted in increased autochthonous primary production as recorded by total or
202 Signalosome appears to be initiated through autochthonous production and cognate binding of CD154 (C
204 nsity, decreased lake ventilation, and lower autochthonous productivity reflects lake deepening betwe
205 ) (KPC) and LSL-Kras(G12D/+); Pdx1(Cre) (KC) autochthonous progression tumor tissue was observed.
210 nts into overlying waters could increase the autochthonous quality of DOM in shallow microtidal estua
211 nt with this, genetic deletion of Msi2 in an autochthonous Ras/p53-driven lung cancer model resulted
212 e I inhibitor to target rRNA synthesis in an autochthonous Rb/p53-deleted mouse SCLC model and found
213 tter define the chemical profile of Campania autochthonous red grape varieties, we analysed the pheno
214 rpose, a controlled raw apple mixture and an autochthonous Saccharomyces bayanus strain were used thr
216 diotherapy, but identical treatment fails in autochthonous sarcomas, which demonstrate immunoediting,
223 n colorectal cancer, and in a mouse model of autochthonous soft-tissue sarcoma driven by a G12D mutat
225 wnstream, likely due to primarily changes in autochthonous sources (e.g., decreased onsite plant biom
228 zation and biofilm formation, differing from autochthonous substrates in the upper layers of the ocea
229 titumor immune response in a syngeneic fully autochthonous system (FBL-3 erythroleukemia cells, C57BL
230 ow spontaneous angiogenesis in a conditional autochthonous system, implicate the angiopoietins as dow
233 cker results were impacted by accounting for autochthonous taxa present in the sink environment.
234 rse HRQOL, higher inflammation and decreased autochthonous taxa relative abundance compared to the re
235 en the library contained only known sources, autochthonous taxa were accounted for and when source pr
239 olera, Vibrio cholerae, has been shown to be autochthonous to riverine, estuarine, and coastal waters
240 onfirming the hypothesis that V. cholerae is autochthonous to the aquatic environment and is a commen
244 issue specimens derived from the spontaneous autochthonous transgenic adenocarcinoma of the mouse pro
246 multiple subcutaneous isograft models and an autochthonous transgenic model of mammary tumorigenesis,
248 was performed in prostatic tissues of TRAMP (autochthonous transgenic mouse model), human CaP patient
251 ent except Antarctica, causing outbreaks and autochthonous transmission in previously disease-free re
253 ll help define the spatial limits of current autochthonous transmission of dengue and chikungunya vir
254 agrees with the geographical distribution of autochthonous transmission of the agent of Lyme borrelio
258 marked variation in the intrinsic ability of autochthonous tumor cells to accumulate p53 and undergo
259 en simultaneously administered enabled acute autochthonous tumor debulking and resulted in durable cl
262 and complete regression of well-established autochthonous tumor in a setting where the host immune s
263 Src inhibitors have not been examined in an autochthonous tumor model that permits assessment of eff
264 n of antiangiogenic therapy in a spontaneous autochthonous tumor model, which may more closely resemb
265 ve shown that TRAIL can reduce tumor growth, autochthonous tumor models have generated conflicting re
268 topes of HER-2/neu leads to the outgrowth of autochthonous tumors after immunizing HER-2/neu transgen
269 d small-animal ultrasound imaging to monitor autochthonous tumors and showed that treatment with the
270 (VEGFR2) monoclonal antibody, on spontaneous autochthonous tumors and their early generation transpla
271 dels, demonstrating that genetically defined autochthonous tumors can be rapidly generated and quanti
272 ved from these more physiologically relevant autochthonous tumors compared with previous studies in t
275 ial protection and therapy against growth of autochthonous tumors in transgenic mouse models of breas
277 what effects GCN2 loss has on the growth of autochthonous tumors that arise in their native microenv
278 dels, including genetic models, we show that autochthonous tumors that lacked T cell infiltration and
279 erstand the role of T(CD8) in the control of autochthonous tumors, we have used mice of the RIP1-Tag4
283 n contrast to previous studies, treatment of autochthonous tumour-bearing animals with Telaglenastat
284 nduced mutp53 ablation, allotransplanted and autochthonous tumours curb their growth, thus extending
285 ion translates into more clinically relevant autochthonous tumours in genetically engineered mouse mo
286 SPR-Cas9 system has been adapted to generate autochthonous tumours in mice, but how these tumours com
288 ected and non-infected traditionally managed autochthonous Tunisian sheep grazing communal natural pa
295 xhibited average bioactivity, with leaves of autochthonous variety Zupljanka standing out as the most
297 ives of this study were to (i) isolate newly autochthonous yeast strains from the Tikves region of Ma
299 us spread to Brazil with the first report of autochthonous Zika transmission in the Americas in March