ライフサイエンスコーパス: autophagic cell death

1 which subsequently triggered AMPK-dependent autophagic cell death.

2 d AMPK activation and subsequently prevented autophagic cell death.

3 may enhance anti-tumor immunity by inducing autophagic cell death.

4 omal degradation during I/R while inhibiting autophagic cell death.

5 Failure to induce AT-1 leads to widespread autophagic cell death.

6 xidative stress to orchestrate apoptotic and autophagic cell death.

7 ized cells to metabolic oxidative stress and autophagic cell death.

8 llular matrix proteolysis, and apoptotic and autophagic cell death.

9 ntiation into mature glial cells followed by autophagic cell death.

10 to TRAIL-induced apoptosis but that undergo autophagic cell death.

11 adder cancer cells from Vitamin K2-triggered autophagic cell death.

12 human cancer cells by causing apoptotic and autophagic cell death.

13 the activation of cGAS and STING results in autophagic cell death.

14 poptotic or non-apoptotic cell death such as autophagic cell death.

15 es by protecting them from IFN-gamma-induced autophagic cell death.

16 BNIP3 by hypoxia-inducible factor to prevent autophagic cell death.

17 fied, including necroptosis, pyroptosis, and autophagic cell death.

18 1-dependent autophagy and Beclin 1-dependent autophagic cell death.

19 e role of DNA-PK in IR-induced apoptotic and autophagic cell death.

20 IP3 transfection augmented As(2)O(3)-induced autophagic cell death.

21 a-mediated apoptosis and caspase-independent autophagic cell death.

22 IP3L), were upregulated in As(2)O(3)-induced autophagic cell death.

23 o elucidate the molecular pathway leading to autophagic cell death.

24 o have the unanticipated effect of promoting autophagic cell death.

25 th had unambiguous morphological features of autophagic cell death.

26 and suggests new links between apoptosis and autophagic cell death.

27 osis, but also function in the regulation of autophagic cell death.

28 is known about the mechanisms that regulate autophagic cell death.

29 , there was significantly more apoptotic and autophagic cell death accompanied by caspase-3 activatio

30 es demonstrated that PARPis induce lysosomal autophagic cell death, accompanied by enhanced mitochond

31 earance by autophagy that is associated with autophagic cell death and neurodegeneration.

32 resistance to MAPK inhibitors by activating autophagic cell death and reversing phenotype switching,

33 and atg genes are required for physiological autophagic cell death and that multiple degradation path

34 f cell death have been described: apoptosis, autophagic cell death, and necrosis.

35 cluding necroptosis, Wallerian degeneration, autophagic cell death, and pyroptosis.

36 cell death apoptosis; however, their role in autophagic cell death (AuCD) or type II programmed cell

37 Foxo likely activates autophagic cell death, because simultaneous inhibition o

38 Thus, ARHI can induce autophagic cell death, but can also promote tumor dorman

39 Induction of autophagic cell death by HDAC inhibitors has clear clini

40 On the other hand, phycocyanin promotes autophagic cell death by inhibiting PI3/Akt/mTOR signali

41 tergent in cells devoid of Bax/Bak1 restores autophagic cell death, collectively indicting that Bax/B

42 s in the peri-infarct region, and suppresses autophagic cell death compared to stroke controls.

43 In a model of ;autophagic cell death', dark was essential for histolysi

44 To the contrary, apelin suppressed autophagic cell death during reoxygenation, which was ac

45 Mutants that prevent autophagic cell death exhibit altered levels of gene tra

46 Analyses of steroid-triggered autophagic cell death identified 932 gene transcripts th

47 ed as controls, neferine was shown to induce autophagic cell death in a panel of cancer cells, includ

48 d from natural products were shown to induce autophagic cell death in apoptosis-resistant cancer cell

49 lysosomal membrane permeability and restore autophagic cell death in Bax/Bak1 double-deleted mouse e

50 targeting Bax only to the lysosome restores autophagic cell death in Bax/Bak1 null cells.

51 metabolic stress and trigger AMPK-dependent autophagic cell death in bladder cancer cells by PI3K/AK

52 cumin induced G(2)/M arrest and nonapoptotic autophagic cell death in both cell types.

53 growth arrest and autophagy are required for autophagic cell death in Drosophila.

54 ting AKT/mTOR/p70S6K signaling, and inducing autophagic cell death in lung cancer cells.

55 Low-dose IR induced massive autophagic cell death in M059J cells that lack the catal

56 These results suggest that ceramide induces autophagic cell death in malignant glioma cells via acti

57 expression of BNIP3, but not BNIP3L, induced autophagic cell death in malignant glioma cells without

58 P3 plays a central role in As(2)O(3)-induced autophagic cell death in malignant glioma cells.

59 e pathways by which As(2)O(3) acts to induce autophagic cell death in malignant glioma cells.

60 y which ceramide acts to induce nonapoptotic autophagic cell death in malignant gliomas.

61 erived from repeated cycles of apoptosis and autophagic cell death in mitotically competent tissues a

62 may mediate both activation of NF-kappaB and autophagic cell death in myositis.

63 AIL may induce both NF-kappaB activation and autophagic cell death in other systems.

64 nduces G2/M cell cycle arrest, apoptotic and autophagic cell death in PANC-1 cells.

65 elease, cytotoxic kinetics, and induction of autophagic cell death in vitro.

66 mice did not undergo necrosis, apoptosis, or autophagic cell death in vivo, even in lines with highly

67 ether, our data provide direct evidence that autophagic cell death is critical for the generation of

68 Importantly, we provide evidence that autophagic cell death is implicated in the pathogenesis

69 Here we show that autophagic cell death is regulated by steroid activation

70 We hypothesized that nonimmune autophagic cell death may play a role in muscle fiber da

71 he absence of canonical apoptosis mediators, autophagic cell death, necroptosis, elimination by shedd

72 ophagy and caspases are required for type II autophagic cell death of Drosophila larval salivary glan

73 ing growth arrest and precedes developmental autophagic cell death of Drosophila salivary glands.

74 lasia Ras homolog member I (ARHI) results in autophagic cell death of human ovarian cancer cells in v

75 lasia Ras homolog member I (ARHI) results in autophagic cell death of human ovarian cancer cells in v

76 Thus, the initiation of rice blast requires autophagic cell death of the conidium.

77 instead act to promote cell death through an autophagic cell death pathway distinct from apoptosis.

78 eviously, we reported that As(2)O(3) induced autophagic cell death (PCD type II) but not apoptosis in

79 implicated in the induction of autophagy and autophagic cell death, possibly through unleashing of th

80 cells to die; however, the mechanism of the autophagic cell death program is unclear.

81 trinsic and/or intrinsic apoptotic pathways, autophagic cell death, reactive oxygen species (ROS)-ind

82 tration of lapatinib with obatoclax elicited autophagic cell death that was attributable to the actio

83 caused synergistic cell killing by eliciting autophagic cell death that was dependent upstream on mit

84 ic cancer activity by inducing apoptotic and autophagic cell death, thereby identifying phycocyanin a

85 um development-including cell-cycle control, autophagic cell death, turgor generation and melanin bio

86 n unchecked, it can be detrimental and cause autophagic cell death/type 2 cell death.

87 , recent studies indicate that apoptotic and autophagic cell death utilize some common regulatory mec

88 ransmembrane-deleted BNIP3 (BNIP3 Delta TM), autophagic cell death was inhibited.

89 Further analysis revealed that autophagic cell death was reduced when cultured human ov

90 genes that are associated with apoptotic and autophagic cell death, we monitored changes in gene tran

91 Although ARHI re-expression led to autophagic cell death when SKOv3 ovarian cancer cells we