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1 ether and that the domain interaction can be autoregulatory.
2 eyond ribosomal RNA, and that they are often autoregulatory.
3 ulatory network we study is that of a single autoregulatory activator gene, and the two copies of the
5 wn renders some PyVs more susceptible to the autoregulatory activities of the miRNA, restoring miRNA
6 that simultaneous loss of both Sox15 and the autoregulatory activity of Su(H) reveals an important ro
8 repertoires (targetomes) while their direct autoregulatory activity on virus-encoded early gene prod
10 h other's transcripts to create a network of autoregulatory and cross-regulatory feedback controls.
14 as the set of promoters for each TF itself (autoregulatory) and the immediately upstream and downstr
15 dback loop illustrates an unexpected mode of autoregulatory behavior of a transcription factor, is co
16 at residue 2, specifically R2G, disrupt the autoregulatory capability of the wild-type beta-tubulin
18 uctural and functional changes that decrease autoregulatory capacity and increase susceptibility to a
20 In vivo trafficking analysis revealed that autoregulatory CD8 T cells are dependent on neuroinflamm
22 nces, pMHC-nanoparticle-induced expansion of autoregulatory CD8(+) T cells can effectively suppress t
27 ndings identify a novel Notch-dependent HRT2 autoregulatory circuit coordinating transcriptional regu
29 thway during cardiogenesis and identifies an autoregulatory circuit in which tin limits its own expre
32 brafish larvae, wound repair is driven by an autoregulatory circuit that generates pro-migratory tiss
37 The Csr system of E. coli contains extensive autoregulatory circuitry, which governs the expression a
39 nome engineering to delete a transcriptional autoregulatory, cis-acting motif in the che-1 zinc-finge
40 arinic m2 receptors (M2Rs) are implicated in autoregulatory control of cholinergic output neurons loc
43 rm to assess the integrity of cardiovascular autoregulatory control systems for risk assessment in he
44 a stable and coherent oscillatory dynamic of autoregulatory control via respiratory entrainment of th
46 reductase-thioredoxin system, generating an autoregulatory cycle that persists until the thiol-deple
49 binds actin monomers through its diaphanous autoregulatory domain (DAD) that resembles a Wiskott-Ald
53 endent localization and cleavage, C-terminal autoregulatory domain and regulation by an upstream open
58 ting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to
61 or their abilities to bind predicted AT-rich autoregulatory element (ARE) boxes within the sabRAS reg
64 egl-5 in the P12.pa cell is influenced by an autoregulatory element that is essential in wild type, b
65 r data show that sRNAs from 3' UTRs serve as autoregulatory elements allowing negative feedback contr
66 It has been shown recently that the main autoregulatory elements of PDZRhoGEF, the autoinhibitory
67 like their eukaryotic counterparts, possess autoregulatory elements that influence how hexameric mot
71 nscription in a site-dependent manner via an autoregulatory enhancer containing a combination of mono
72 gesting a mechanism for priming the 3' Atoh1 autoregulatory enhancer needed for hair cell expression.
74 domain is complemented by an adjacent 2.3-kb autoregulatory enhancer that is able to activate a heter
76 tion by Crispr/Cas9-mediated deletion of the autoregulatory exon induces expression of all SR protein
77 ranscriptional regulator, deformed epidermal autoregulatory factor 1 (Deaf1), that can regulate PTA e
79 widely deployed in cell lineages, where the autoregulatory factor controls the activity of a battery
80 cade is inhibited by farnesol, a C. albicans autoregulatory factor, and small molecules such as dodec
81 tional regulatory factor, deformed epidermal autoregulatory factor-1 (DEAF-1), also contributes to th
82 ated to atrophy, inflammation, or changes in autoregulatory factors or growth factors remains to be d
83 delayed ischemic deficits due to vasospasm, autoregulatory failure, and intravascular volume contrac
85 e metabolism of FICZ, thereby disrupting the autoregulatory feedback control of cytochrome P4501 syst
89 ere, we show the existence of a proapoptotic autoregulatory feedback loop between p73, YAP, and the p
92 nism for genetic disease by disruption of an autoregulatory feedback loop critical for maintenance of
94 ings suggest the presence of a c-Myb-miR-15a autoregulatory feedback loop of potential importance in
95 provides a full-loop mechanism for a classic autoregulatory feedback loop proposed ~25 years ago.
96 hormone target and is involved in a positive autoregulatory feedback loop that modulates thyroid horm
97 ere we show that a hippocampal BDNF-positive autoregulatory feedback loop via CCAAT-enhancer binding
99 ic marks, along with its participation in an autoregulatory feedback loop with genes known to transfo
100 to its own promoter, defining a new negative autoregulatory feedback loop within the core clock.
107 ostatic hypotheses by explicitly emphasizing autoregulatory feedback loops and known synaptic biology
108 splicing events that could be implicated in autoregulatory feedback loops in RBM39, HNRNPM, and U2AF
112 transcription in SLE T cells, we propose an autoregulatory feedback mechanism between CREM and AP-1.
113 irst miRNA that monitors c-Myc levels via an autoregulatory feedback mechanism in response to serum s
114 criptional reprogramming includes a positive autoregulatory feedback mechanism in which ectopic PHF7
115 current noncoding mutations in disrupting an autoregulatory feedback mechanism, thereby deregulating
116 gth viral genome, this mechanism promotes an autoregulatory feedback that decreases expression of tat
117 e a requirement for positive transcriptional autoregulatory feedback to attain the level of the neuro
118 RecADeltaC17 mutants, lacking a C-terminal autoregulatory flap, also promote strand exchange in a 5
120 ation of HdrR prevents the positive feedback autoregulatory function of HdrR, thereby maintaining a l
127 very of viral master circuits: virus-encoded autoregulatory gene networks that autonomously control v
128 ve more interactions with microRNAs than non-autoregulatory genes and 89% of autoregulatory TFs were
130 Our findings establish the DnaB collar as an autoregulatory hub that controls the ability of the heli
131 rives monocyte proinflammatory processes and autoregulatory IL-10 in a serum IgE-dependent manner.
133 nsfer function analysis (gain and phase) and autoregulatory index (ARI) fit from spontaneous oscillat
134 blood flow, cerebral perfusion pressure, and autoregulatory index decreased markedly during hypotensi
135 NP did not prevent reductions in CBF, CPP or autoregulatory index during combined hypotension and FPI
136 blood flow, cerebral perfusion pressure, and autoregulatory index during hypotension in females but i
137 artery diameter, intracranial pressure, and autoregulatory index were determined before and after fl
139 ndividuals in all (steady-state and dynamic) autoregulatory indices, ranging from low (almost absent)
140 s, thereby demonstrating the conservation of autoregulatory infrastructure across the IpaH enzyme fam
141 es provided evidence for crossregulatory and autoregulatory interactions among components of this com
142 ong with controlling membrane binding, these autoregulatory interactions inhibit the ability of Nwk-S
144 by eIF2alpha phosphorylation destabilizes an autoregulatory intramolecular interaction within eIF2alp
145 HAT assays suggest that the RING domain, the autoregulatory loop (AL) within the HAT domain, and the
146 thesis, our observations reveal a GATA1-heme autoregulatory loop and implicate GATA1 and heme as the
147 d middle meiotic promoter through a positive autoregulatory loop and is repressed in vegetative cells
150 port a previously unrecognized bidirectional autoregulatory loop between MTA1 and tumor suppressor al
153 these mechanisms Blimp-1 participates in an autoregulatory loop by which IL-2 induces Prdm1 expressi
156 d that Ntl functions normally to protect the autoregulatory loop from endogenous RA by directly activ
157 ence of a nuclear KIT-driven NFKBIB-RELA-KIT autoregulatory loop in GIST tumorigenesis, which are pot
159 tes the activity of Spo0A through a positive autoregulatory loop involving KinC, a histidine kinase t
160 ory circuitry of ES cells, which includes an autoregulatory loop involving the pluripotency regulator
161 newly identified control should result in an autoregulatory loop limiting the amount of OmrA/B sRNAs.
163 e NDRs, established by OCT4, in ensuring the autoregulatory loop of pluripotency and, furthermore, th
164 occupancy of the Etv1 gene itself, and this autoregulatory loop preceded ETV1 binding and activation
165 that SHH and Atoh1 contribute to a positive autoregulatory loop promoting neuronal precursor expansi
167 CL6 gene alterations is to bypass a negative autoregulatory loop that controls its transcription.
168 and revealed a novel STARS-SRF feed-forward autoregulatory loop that could play an essential role in
169 factors OCT4, NANOG and SOX2 form a positive autoregulatory loop that is pivotal for maintaining the
170 A2 and 1B1, thereby also participating in an autoregulatory loop that keeps its own steady-state conc
171 ating that these proteins may function in an autoregulatory loop that maintains appropriate levels of
172 ase, in part through the up-regulation of an autoregulatory loop that promotes podosome formation.
173 r cells, the enhancer and PTF1a establish an autoregulatory loop that reinforces and maintains Ptf1a
174 ion, whereas ER71 and SOX9 participate in an autoregulatory loop to sustain each other's expression a
175 y interfering with IL-13's negative feedback autoregulatory loop under MEK/ERK-dependent conditions.
176 tudy, we characterize a Neurogenin3 positive autoregulatory loop whereby this factor may rapidly indu
177 dence that CEH-17 participates in a positive autoregulatory loop with CEH-14 in ALA, and that CEH-10,
178 ow that TAL1 forms a positive interconnected autoregulatory loop with GATA3 and RUNX1 and that the TA
179 vertebrate embryo depends on a Brachyury/Wnt autoregulatory loop within the posterior mesodermal prog
180 Together, we identified a novel p53-RNPC1 autoregulatory loop, and our findings suggest that RNPC1
181 t the BDNF gene is a subject to an extensive autoregulatory loop, where TrkB signaling upregulates th
193 Indeed, the trimeric PTF1 complex forms dual autoregulatory loops with the Ptf1a and Rbpjl genes that
196 resynaptic receptors on POMC terminals in an autoregulatory manner to limit continued transmission.
197 otubule motor-cargo interface and associated autoregulatory mechanism can be manipulated using a smal
198 first to implicate ligand dimerization as an autoregulatory mechanism for growth factor bioactivity a
200 ependent inactivation (CDI) is a fundamental autoregulatory mechanism in Ca(V)1 and Ca(V)2 voltage-ga
203 SII repair, and psbA translation, suggest an autoregulatory mechanism in which the light-induced degr
204 A1 represent a p53-independent bidirectional autoregulatory mechanism in which these two opposites ac
206 omes of opioid drugs, which suggests that an autoregulatory mechanism may function in opioid systems.
207 is critically dependent on a self-sustaining autoregulatory mechanism mediated by the Pit-1 protein.
211 n FUS expression achieved by saturating this autoregulatory mechanism produces a rapidly progressive
213 eptide products and reveal clues for a novel autoregulatory mechanism that might have significant imp
215 report that Nanog is subjected to a negative autoregulatory mechanism, i.e., autorepression, in ESCs,
221 on of individual proteins correlate to known autoregulatory mechanisms and extend the network of ribo
223 osomal protein genes are often controlled by autoregulatory mechanisms in which a protein encoded in
227 neurons in mice relies on a transcriptional autoregulatory module initiated via transient activity o
228 aB in a novel feed-forward, self-amplifying, autoregulatory module regulated by the ERBB family of gr
229 roved that the oligopeptide functioned as an autoregulatory molecule responsible for the density-depe
233 tion is highly conserved in the beta-tubulin autoregulatory MREI (methionine-arginine-glutamic acid-i
235 sigmas and their promoters by leveraging the autoregulatory nature of ECF sigmas as a means of promot
236 e that Chtop expression is controlled via an autoregulatory negative feedback loop whereby Chtop bind
237 d supply induces Pten expression creating an autoregulatory negative feedback loop, whereas complete
241 ormed parameter searches to demonstrate that autoregulatory negative-feedback loops of the redundant
250 osophila circadian oscillator is composed of autoregulatory period/timeless (per/tim) and Clock (Clk)
251 teins reflects the operation of an adaptive, autoregulatory process of functionally significant aggre
252 then by creating an environment in which an autoregulatory process restricts the immune response to
254 ogene and that Erk molecules possess unusual autoregulatory properties, some of them independent of T
261 light (functional hyperemia) is a well-known autoregulatory response driven by increased neural activ
262 -resolved OCT angiography to investigate the autoregulatory response in the 3 parafoveal retinal plex
263 ngiography was able to show that the retinal autoregulatory response to hyperoxia affects only the de
265 values in the NoDR group likely represent an autoregulatory response to increased metabolic demand, w
267 ectively, these findings indicate a positive autoregulatory role for INSL3 signaling in maintaining t
271 ion of POMC neurons such that attributing an autoregulatory role to opioids must include consideratio
273 tors and demonstrates an unexpected level of autoregulatory scaffolding in mammalian stress-activated
274 re dedicated protein kinases regulated by an autoregulatory segment C terminus of the catalytic core
277 S. acidiscabies, a gene cluster encoding GBL autoregulatory signaling homologs was identified and cha
278 ce DUSP1 mRNA expression, suggesting that an autoregulatory signaling loop may be activated by Stxs.
280 lector gene engrailed is silenced through an autoregulatory silencing mechanism that requires the PRC
281 omal rearrangements, mutations of a negative autoregulatory site in the BCL6 promoter region and aber
282 0 vs. 3.7 +/- 0.8 mmHg) while increasing the autoregulatory slope (0.10 +/- 0.05 vs. 0.24 +/- 0.08 cm
284 , trauma severity, intracranial pressure, or autoregulatory status, and thus represent a discrete phe
286 reventing cachexia, we developed a molecular autoregulatory system involving a single recombinant ade
292 4) forms several H-bonds with the N-terminal autoregulatory tail but is far from the catalytic Fe(II)
293 NAs than non-autoregulatory genes and 89% of autoregulatory TFs were found in dual feedback motifs wi
294 d organismal physiology are controlled by an autoregulatory transcription-translation feedback loop t
296 e circadian clock in mammals is driven by an autoregulatory transcriptional feedback mechanism that t
297 ically integrated circuits that use bistable autoregulatory transcriptional feedback to retain memory
299 as selective removal of I-E on DCs abrogated autoregulatory Treg formation and T1D protection, select
300 cy is established when the expression of the autoregulatory viral trans-activating factor Tat is redu