ライフサイエンスコーパス: axonally

1 rojecting microtubules from those projecting axonally.

2 esults show that JNK and p38 are transported axonally and may mediate the transfer of diabetes-relate

3 aining Fragile X proteins that are expressed axonally and presynaptically in a subset of circuits.

4 at the secretory pathway delivery of CB1R is axonally biased and that surface expressed CB1R is more

5 al pattern of progression of lesions between axonally connected areas results from the axonal transpo

6 was synchronous both within and between the axonally connected networks, i.e. mimicking both local a

7 ii) that similar areas are more likely to be axonally connected, as predicted by the homophily princi

8 gH/gL fusion complex mediates entry into the axonally contacted cell by fusion of the closely apposed

9 usly reported that productive replication of axonally delivered genomes is facilitated by pseudorabie

10 gulated by apoptosis through competition for axonally derived neuregulin.

11 wann cells, MEP glial development depends on axonally derived neuregulin1.

12 Moreover, we show that axonally derived neuronal pentraxins NP1 and NPR are req

13 cell survival may be regulated by access to axonally derived NRG.

14 ional signals derived from the notochord and axonally derived signals.

15 n of GAKIN constructs led to the loss of the axonally differentiated neurites.

16 ssociation may aid in sorting of GAP-43 into axonally directed vesicles in the trans-Golgi network.

17 We identify P180/RRBP1 as an axonally distributed ribosome receptor that regulates lo

18 was blocked by tetrodotoxin, indicating that axonally generated action potentials were necessary to r

19 Imaging of an intra-axonally injected fluorescent [Ca(2+)] indicator reveale

20 hannel Kv4.2 and is sufficient to target the axonally localized channels Kv1.3 and Kv1.4 to the dendr

21 embrane association increases the ability of axonally localized Nmnat2 to preserve transected neurite

22 xonal defasciculation events by acting as an axonally localized repellent and that correct motor axon

23 BDNF induces the translation of axonally localized SMAD1/5/8 transcripts.

24 that expression of a reporter mRNA with the axonally localizing beta-actin mRNA 3'UTR competes with

25 se, rat and human neurons, dendritically and axonally polarized transmembrane proteins are recognized

26 Division of spikelets into likely axonally propagated and non-propagated groups (based on

27 , gp120 injected into the CP was transported axonally retrograde to the SN, causing delayed DN loss t

28 e Luman expression either neuronally or just axonally significantly impaired the ability of 24-h inju

29 'UTR competition to address the functions of axonally synthesized beta-actin and GAP-43 proteins.

30 Our results thus suggest that axonally synthesized lamin B plays a crucial role in axo

31 is increased during regeneration, and intra-axonally synthesized proteins have been shown to contrib

32 Detection of the mRNAs encoding each of the axonally synthesized proteins identified by mass spectro

33 Axonally synthesized proteins support nerve regeneration

34 ldolase C/Zebrin II) were included among the axonally synthesized proteins.

35 urons and proteomics methodology to identify axonally synthesized proteins.

36 Overexpression of axonally targeted amphoterin mRNA increases axon outgrow

37 ly targeted GAP-43 mRNA increased length and axonally targeted beta-actin mRNA increased branching of

38 Finally, in ovo electroporation of axonally targeted GAP-43 mRNA increased length and axona

39 Axonally targeted NMNAT1 localized to vesicular structur

40 These axonally targeted palmitoylation motifs also mediate tar

41 Identifying axonally targeted PATs might thus provide insights into

42 We find that ZIKV can be transported axonally, thereby enhancing virus spread within the brai

43 We show the antiNOS-2 RNA is axonally trafficked and demonstrate that this is regulat

44 inked neurologic diseases and that replacing axonally translated proteins serves as a therapeutic app

45 get field, suggesting VDUP1 regulation by an axonally transmitted signal.

46 yrus, findings that lead us to conclude that axonally transported APP gives rise to Abeta peptides th

47 the hypothesis that APP-CTFs, generated from axonally transported APP, are further metabolized to Abe

48 nal kinase (JNK) and p38 are bidirectionally axonally transported at fast rates in sciatic nerve.

49 APP is axonally transported by the fast anterograde component.

50 nt potential bottlenecks for the movement of axonally transported cargoes.

51 ted by using intra-PVH administration of the axonally transported catecholamine immunotoxin, antiDBH-

52 oradrenergic inputs into the mPFC, using the axonally transported catecholamine immunotoxin, saporin-

53 In adult neurons, KIF3C is axonally transported from the cell body and is enriched

54 rotease which initiates Abeta production, is axonally transported in neurons and accumulates in dystr

55 lular domains, thereby effecting delivery of axonally transported materials.

56 , there is no evidence for the deposition of axonally transported neurofilaments into a persistently

57 that KIFC2 localizes with some, but not all, axonally transported organelles.

58 latter observations have suggested that APP, axonally transported to nerve terminals, may be processe

59 ensory nerve endings, where these agents are axonally transported to the central nervous system, sugg

60 VEGF-A was axonally transported to the DRG via the sciatic nerve.

61 GT1b ganglioside is axonally transported to the spinal cord dorsal horn and

62 step in TeNT H(C) sorting but is absent from axonally transported vesicles.

63 Cytoskeletal proteins are axonally transported with slow components a and b (SCa a

64 , though very low in abundance, is taken up, axonally transported, and passed on to synaptically conn

65 rotropic viruses spread to CNS tissues trans-axonally, where they induce a strong type 1 immune respo