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1 and ovary expressed basic helix-loop-helix (bHLH) transcription factor).
2 MAX also dimerizes with MYC, an oncogenic bHLH transcription factor.
3 The C. elegans genome encodes a single Hand bHLH transcription factor.
4 epends on Olig2, one of the five Olig family bHLH transcription factors.
5 forms homodimers and heterodimers with other bHLH transcription factors.
6 ication is achieved through few well-defined bHLH transcription factors.
7 aling by Notch and Sox2 on the expression of bHLH transcription factors.
8 vation of NvHes genes, a conserved family of bHLH transcription factors.
9 heterodimerize with and negatively regulate bHLH transcription factors.
10 roviding new insight into gene regulation by bHLH transcription factors.
11 ic gene expression and activation by Myb and bHLH transcription factors.
12 yase and pectinesterase, are targets of both bHLH transcription factors.
13 in its capacity as a basic helix-loop-helix (bHLH) transcription factor.
14 hogenesis is HFR1, a basic helix-loop-helix (bHLH) transcription factor.
15 FACTORs, a group of basic helix-loop-helix (bHLH) transcription factors.
16 tivity of neurogenic basic helix-loop-helix (bHLH) transcription factors.
17 ly activate myogenic basic helix-loop-helix (bHLH) transcription factors.
18 ompromises the onset of achaete-scute family bHLH transcription factor 1 (Ascl-1)(+) vomeronasal prog
20 n of sT and the cell fate-determinant atonal bHLH transcription factor 1 (ATOH1) leads to development
21 a complex with the Notch effector hes family bHLH transcription factor 1 (HES1) and the protein deace
22 nding factor 1 (LEF1) and mesoderm posterior BHLH transcription factor 1 (MESP1; from mesoderm to car
23 tivation protein Ascl1 (achaete-scute family bHLH transcription factor 1) in proliferating hippocampa
25 sion of either Twist1 (encoding twist family bHLH transcription factor 1, known as Twist) or Snai1 (e
26 iscovered that the gene single minded family bHLH transcription factor 1a (sim1a) is dynamically expr
27 which encodes a photomorphogenesis-promoting bHLH transcription factor, acts downstream of SPA1 and i
28 maize R gene has been used to suggest that a bHLH transcription factor also participates in this proc
30 s deduced where targets, such as AP2/ERF and bHLH transcription factors and chromatin remodelers form
31 lators of neurogenesis, including neurogenic bHLH transcription factors and dorsal interneuron progen
33 ed genes that could be direct targets of the bHLH transcription factors and therefore indirect target
34 rabidopsis, a ternary complex formed by MYB, bHLH transcription factors and TTG1 modulates unicellula
35 emi, which encodes a basic helix-loop-helix (bHLH) transcription factor and which controls these appa
36 development through basic-helix-loop-helix (bHLH) transcription factors and promotes astrocytosis.
37 ered that it encodes a PAS-domain-containing bHLH transcription factor, and that it is expressed in a
38 h encodes a class II basic helix-loop-helix (bHLH) transcription factor, and causes Saethre-Chotzen s
39 cell cycle proteins, basic helix-loop-helix (bHLH) transcription factors, and other retinal cell mark
41 ut the Hey family of basic helix-loop-helix (bHLH) transcription factors are candidates for mediating
45 rl), a Hairy-related basic helix-loop-helix (bHLH) transcription factor, as a negative regulator of c
46 ediated overexpression of a single gene, the bHLH transcription factor Ascl1, redirected the fate of
47 tube depends on the basic helix-loop-helix (bHLH) transcription factors Ascl1 (Mash1) and Neurog2 (N
49 In a wide range of vertebrate species, the bHLH transcription factor Ath5 is tightly associated wit
50 retinoblasts, and functions upstream of the bHLH transcription factors ath5/atoh7 and neurod, and th
51 on resulted from an increase in the level of bHLH transcription factor Atoh1 in response to inhibitio
57 itors expressing the basic helix-loop-helix (bHLH) transcription factor, Atoh7, which is necessary fo
58 a mouse homolog of the Drosophila proneural bHLH transcription factor Atonal, is essential in the de
60 hree closely related basic helix-loop-helix (bHLH) transcription factors, BEE1, BEE2, and BEE3, as pr
61 insect and RNAi to determine functions of 19 bHLH transcription factors belonging to PAS and HES fami
63 ce deficient for the basic helix-loop-helix (bHLH) transcription factor Bhlhe40 (Bhlhe40(-/-)) are re
64 Zfp148, and Plzf, overexpress a novel Tohlh2 bHLH transcription factor, but lack LIM homeobox gene Lh
65 This activation required MYC proto-oncogene bHLH transcription factor (c-Myc) and depended on the ch
67 first neural target of Ptf1a and revealing a bHLH transcription factor cascade functioning in the spe
69 ng the hairy-related basic helix-loop-helix (bHLH) transcription factor CHF1/Hey2 develop a thin-wall
72 of master regulatory basic-helix-loop-helix (bHLH) transcription factors controls the initiation, pro
74 , we showed that the basic Helix-Loop-Helix (bHLH) transcription factor Cucumis sativus Irregular Vas
75 pression of specific basic-helix-loop-helix (bHLH) transcription factors defines many types of cellul
77 have identified two basic helix-loop-helix (bHLH) transcription factors, designated PHYTOCHROME-INTE
78 e, both display significant overlap with the bHLH transcription factor DIMM, a known neuroendocrine (
79 ate the expression and function of proneural bHLH transcription factors during the onset of mouse ret
81 bers of the group XI basic helix-loop-helix (bHLH) transcription factors encoded by LOTUS JAPONICUS R
82 es expression of two basic helix loop helix (bHLH) transcription factor encoding genes, ash1a (achaet
83 enes in opr3 encode lipoxygenase, a putative bHLH transcription factor, epithiospecifier protein and
84 ECs express mAsh1, a basic helix-loop-helix (bHLH) transcription factor essential for NE cell differe
85 3, neurogenin1) is a basic helix-loop-helix (bHLH) transcription factor essential for neuronal differ
88 HAND2 (dHAND) is a basic helix-loop-helix (bHLH) transcription factor expressed in numerous tissues
90 g, which has previously been shown to induce bHLH transcription factor expression, increased beta-cat
91 cies, Arabidopsis, in which three paralogous bHLH transcription factors, FAMA, MUTE and SPCH, control
92 gested that the large-scale expansion of the bHLH transcription factor family occurred before the div
93 g the composition and diversity of the apple bHLH transcription factor family that will provide a pla
97 e identification and characterization of 175 bHLH transcription factors from apple (Malus x domestica
98 nteracting Factors (PIFs) by releasing these bHLH transcription factors from phytochrome B-mediated i
99 jasmonate-regulated basic helix-loop-helix (bHLH) transcription factor from clade IVa inducing the m
100 ults suggest that variation in the timing of bHLH transcription factor gene expression can explain th
101 ch signaling revealed a cascade of proneural bHLH transcription factor gene expression that correlate
103 Phylogenetic analysis indicates that these bHLH transcription factor genes are orthologous to Arabi
105 utative (a PIL5, a hypothetic protein, and a bHLH transcription factor) genes based on the annotated
106 s the Notch effector basic helix-loop-helix (bHLH) transcription factor hairy and enhancer of split 1
107 the highly conserved basic helix-loop-helix (bHLH) transcription factor Hand is expressed in cardiobl
110 upregulation of the basic helix-loop-helix (bHLH) transcription factor Hand1, restricted exclusively
111 ebrafish of two edn1 downstream targets, the bHLH transcription factor Hand2 and the homeobox transcr
118 The MyoD family of basic helix-loop-helix (bHLH) transcription factors has the remarkable ability t
119 1, a phy-interacting basic helix-loop-helix (bHLH) transcription factor, has been shown to negatively
120 olecular level that neuronal differentiation bHLH transcription factors have distinct lineage-specifi
121 The genes encoding basic helix-loop-helix (bHLH) transcription factors have been implicated in many
122 (2014) describe the signals regulated by the bHLH transcription factor HEC1 during Arabidopsis stem c
124 s for expression of Notch and the hes family bHLH transcription factor (HES1) in colon tissues from m
125 by interfering with the assembly of myogenic bHLH transcription factor heterodimers on E-box sequence
126 Here, we report that the Beta3/Olig-type bHLH transcription factor hlh-16 is L/R asymmetrically e
127 h sexes requires the basic-helix-loop-helix (bHLH) transcription factor HLH-2, the sole ortholog of t
128 ere, we identify the basic helix-loop-helix (bHLH) transcription factor homolog of brassinosteroid en
129 d degradation of the basic helix-loop-helix (bHLH) transcription factor human achaete-scute homolog 1
130 lutionally conserved basic helix-loop-helix (bHLH) transcription factors implicated in development of
131 ) demonstrate unsuspected cross-talk between bHLH transcription factors, important regulators of orga
132 olated a dominant mutation in an R/B-related bHLH transcription factor in the course of studying Arab
133 l cues in the CNS and to examine the role of bHLH transcription factors in adult tissue regeneration.
134 y PHYTOCHROME-INTERACTING FACTOR (PIF)-class bHLH transcription factors in darkness, but light-activa
136 l1), which encodes a basic helix-loop-helix (bHLH) transcription factor, in the regulation of both as
137 ibit the function of basic helix-loop-helix (bHLH) transcription factors including those that regulat
138 oteins are known to negatively regulate many bHLH transcription factors, including Math1, in a number
139 in-22, a Hes-related basic helix-loop-helix (bHLH) transcription factor, increase seam cell number va
140 inhibit the atypical basic helix-loop-helix (bHLH) transcription factor INCREASED LEAF INCLINATION1 B
141 e show that myogenic basic helix-loop-helix (bHLH) transcription factors induce myomaker expression i
143 irect target of EZH2, and repression of this bHLH transcription factor is critical for neuronal diffe
146 Twist1, a class II basic-helix-loop-helix (bHLH) transcription factor, is expressed during early EC
147 report that Ptf1a, a basic-helix-loop-helix (bHLH) transcription factor, is transiently expressed by
148 mologue 2 (Ascl2)--a basic helix-loop-helix (bHLH) transcription factor--is selectively upregulated i
151 ow that expression of olig2, which encodes a bHLH transcription factor, marks a distinct subset of ne
155 mechanism that involved the upregulation of bHLH transcription factor, Math1 (mouse Atoh1), differen
157 The Wnt-regulated basic helix-loop-helix (bHLH) transcription factor mesogenin 1 (Msgn1) has been
158 al profiling of Wnt3a (-/-) embryos that the bHLH transcription factor, Mesogenin1 (Msgn1), is a dire
160 gastric cell populations that identified the bHLH transcription factor Mist1 as a potential ZC regula
165 1) and identified EAN1 as a tapetum-specific bHLH transcription factor necessary for tapetum degenera
166 BMP4 stimulation promotes Id2 binding to the bHLH transcription factor NeuroD, which is required for
167 ar expression of the basic helix-loop-helix (bHLH) transcription factor neuroD in the persistently ne
169 , we have identified basic helix-loop-helix (bHLH) transcription factors Neurod2 and Neurod6 as key r
171 In the present work, we demonstrate that the bHLH transcription factor NeuroD6 is specifically and tr
175 ion of the proneural basic helix-loop-helix (bHLH) transcription factors Neurog2 or Ascl1 downregulat
176 We identified the basic helix-loop-helix (bHLH) transcription factor Neurogenic Differentiation 2
178 enhancers, including basic helix-loop-helix (bHLH) transcription factor Neurogenin/Math/atonal and Ma
179 Expression of the basic helix-loop-helix (bHLH) transcription factor Neurogenin1 (Neurog1) coincid
181 is is positively regulated by the pro-neural bHLH transcription factors Ngn1 and NeuroD, but the fact
184 eport that proneural basic helix-loop-helix (bHLH) transcription factors not only initiate neuronal d
185 enesis and depends upon the function of both bHLH transcription factors, notably Hand2, and homeodoma
186 demonstrate that the expression of Bhlhb5, a bHLH transcription factor of the Olig family, is tightly
188 he activity of three basic-helix-loop-helix (bHLH) transcription factors of the PHYTOCHROME INTERACTI
192 , Zfp488 can interact and cooperate with the bHLH transcription factor Olig2 to promote precocious an
194 ing neural tube, the basic helix-loop-helix (bHLH) transcription factor Olig2 interacts with the home
195 N) domain of the developing spinal cord, the bHLH transcription factor, Olig2, plays critical roles i
196 We show that the basic helix-loop-helix (bHLH) transcription factor Olig3 is expressed in the ent
199 m by which increasing temperature causes the bHLH transcription factor PHYTOCHROME INTERACTING FACTOR
200 ncreased auxin biosynthesis, mediated by the bHLH transcription factor PHYTOCHROME-INTERACTING FACTOR
203 (pifq) lacking four phytochrome-interacting bHLH transcription factors (PIF1, 3, 4, and 5) is consti
204 (phy)-interacting factor (PIF) subfamily of bHLH transcription factors (PIF1, PIF3, PIF4, and PIF5).
207 We show that the basic helix-loop-helix (bHLH) transcription factor PIF7 (phytochrome-interacting
208 as SPA1/COP1 E3 ubiquitin ligase complex and bHLH transcription factors PIFs, would partially explain
209 family of four Phytochrome (phy)-Interacting bHLH transcription Factors (PIFs) collectively promote s
210 n of phy-interacting basic Helix Loop Helix (bHLH) transcription factors (PIFs), such as PIF3, thereb
214 Long Hypocotyl in Far-Red Light 1 (HFR1), a bHLH transcription factor, plays a critical role in prom
215 DYSFUNCTIONAL TAPETUM 1 (DYT1), a putative bHLH transcription factor, plays a critical role in regu
217 ycle-specific iron deficiency response and a bHLH transcription factor, POPEYE (PYE), that may play a
218 Here we show that Arabidopsis lacking two bHLH transcription factors produces pollen without sperm
219 NeuroD2, a neuronal basic helix-loop-helix (bHLH) transcription factor, promotes the postnatal survi
226 the SPATULA (SPT) gene, which also encodes a bHLH transcription factor required for development of th
227 subpopulation of NCCs that expresses Ngn2, a bHLH transcription factor required for sensory neurogene
229 lfactory-1, OLF1), a basic helix-loop-helix (bHLH) transcription factor required for B-lineage commit
230 gene that encodes a basic helix-loop-helix (bHLH) transcription factor required for proper distal ti
231 r-specific predicted basic helix-loop-helix (bHLH) transcription factor required for tapetal differen
232 oneural genes encode basic-helix-loop-helix (bHLH) transcription factors required for neural precurso
238 This includes the basic helix-loop-helix (bHLH) transcription factors SPEECHLESS (SPCH), MUTE, FAM
239 ila retina, stochastic expression of the PAS-bHLH transcription factor Spineless (Ss) controls photor
240 ophila eye, stochastic expression of the PAS-bHLH transcription factor Spineless (Ss) determines a ra
243 receptor family (phyA to phyE) interact with bHLH transcription factors, such as PIF3, and induce cha
246 interaction of Pfr with a small subfamily of bHLH transcription factors, termed Phy-Interacting Facto
250 TION FACTOR (FIT), a basic helix-loop-helix (bHLH) transcription factor (TF), regulates root Fe acqui
252 YC2a, b, c) encoding basic helix-loop-helix (bHLH) transcription factors (TFs) whose expression is ra
253 f two genes encoding basic-helix-loop-helix (bHLH) transcription factors (TFs), NtMYC2a and NtMYC2b f
254 Sohlh1 represents the first testis-specific bHLH transcription factor that is essential for spermato
255 including IAA-Leu Resistant3 (ILR3), another bHLH transcription factor that is involved in metal ion
256 trated that AmeloD is a novel tooth-specific bHLH transcription factor that may regulate tooth develo
257 endent, per ARNT-sim (PAS) domain containing bHLH transcription factor that mediates adaptive respons
260 his question, we focused on Atoh1 (Math1), a bHLH transcription factor that specifies distinct neuron
261 ith inhibition of the Notch effector Hey1, a bHLH transcription factor that we here characterize as a
262 , BEE1 and BEE3 genes encode closely related bHLH transcription factors that act redundantly to speci
263 MYC2, MYC3 and MYC4 are JAZ-interacting bHLH transcription factors that play a major role in con
265 nctions of Myf5 and MyoD, two highly related bHLH transcription factors that regulate skeletal muscle
266 ng analysis we identified five MYB and three bHLH transcription factors that were upregulated in the
267 is a multifunctional basic helix-loop-helix (bHLH) transcription factor that has been shown to be a p
268 molog 1 (Atoh1) is a basic helix-loop-helix (bHLH) transcription factor that is essential for the gen
270 S (SPCH), encoding a basic helix-loop-helix (bHLH) transcription factor that is necessary and suffici
271 PTF1a is an unusual basic helix-loop-helix (bHLH) transcription factor that is required for the deve
272 are closely related basic helix-loop-helix (bHLH) transcription factors that are expressed in myelin
273 s (PIFs) are nuclear basic helix-loop-helix (bHLH) transcription factors that negatively regulate pho
274 des highly conserved basic helix-loop-helix (bHLH) transcription factors that play crucial roles in c
275 n TWIST2 and TWIST1 encode highly homologous bHLH transcription factors, the finding that TWIST2 rece
276 hese results uncover a novel mechanism for a bHLH transcription factor to recognize a unique spatial
277 a functionally relevant target recruited by bHLH transcription factors to induce cell cycle arrest i
278 he ability of neural basic helix-loop-helix (bHLH) transcription factors to activate transcriptional
279 h the MyoD family of basic helix-loop-helix (bHLH) transcription factors to drive skeletal muscle dev
280 ing (IDs) antagonize basic-helix-loop-helix (bHLH) transcription factors to inhibit differentiation a
282 f the 29 candidate genes in this region, the bHLH transcription factor, TWIST2, was initially sequenc
285 a nonsynonymous SNP mutation on exon 5 of a bHLH transcription factor was found to elevate the propo
286 vonol-4-reductase (DFR) in leaves, whereas a bHLH transcription factor was highly correlated with fla
289 study, we identified a novel tooth-specific bHLH transcription factor, which we named AmeloD, by scr
291 y32 (ms32) encodes a basic helix-loop-helix (bHLH) transcription factor, which functions as an import
292 E SIX-LIKE1 (MpRSL1) basic-helix-loop-helix (bHLH) transcription factor, which is directly repressed
293 The stem cell leukemia (SCL) gene encodes a bHLH transcription factor with a pivotal role in hematop
294 transcriptional repressor Hes-related family BHLH transcription factor with YRPW motif 1 (Hey1), down
296 (SCL) gene encodes a basic helix-loop-helix (bHLH) transcription factor with an essential role in spe
297 was GRMZM2G021276, a basic helix-loop-helix (bHLH) transcription factor with tassel-specific expressi
298 enes encode putative basic helix-loop-helix (bHLH) transcription factors with overlapping functionali
299 up-regulation of two basic helix-loop-helix (bHLH) transcription factors with predicted effector bind