ライフサイエンスコーパス: bacterial

1 n dromedary camel (ICab) immunized against a bacterial 14TM helix transporter, NorC, from Staphylococ

2 Bacterial 16S ribosomal RNA analyses were performed on s

3 ropensity to form biofilms, surface-adherent bacterial accumulations that are remarkably resistant to

4 genetic analysis of more than 4000 annotated bacterial acid phosphatases was carried out.

5 Disrupting bacterial adherence to the intestinal surface could pote

6 his new material may be developed as an anti-bacterial agent for prolonging the shelf life of tuna fi

7 mbled genomes we identified over 90 putative bacterial and archaeal genomic families and nearly 300 p

8 residues in sequence motifs conserved across bacterial and eukaryotic orthologs modulate the function

9 Here, we examined soil bacterial and fungal diversity and community composition

10 l biomass and metabolic diversity but higher bacterial and fungal species richness.

11 ence of expansin genes in diverse species of bacterial and fungal wilt-inducing pathogens suggests th

12 g of specimens is challenging because of low bacterial and high human DNA abundances.

13 phenomenon "activation by inhibition" using bacterial and human HtrA proteases as models.

14 y the 20rDNA line is hyper-resistant to both bacterial and nematode infections.

15 e used, which can increase susceptibility to bacterial and viral infections.

16 ing anti-inflammatory, anti-depressant, anti-bacterial, anti-viral, anti-fungal, and anti-cancer drug

17 type of the S-locus in Petunia inflata using bacterial artificial chromosome clones collectively cont

18 effective in preventing blood coagulation or bacterial attachment, but their chain conformation, whil

19 ntial but homeostatic contributor to complex bacterial behaviors.

20 ses in shaping geographical patterns of soil bacterial beta diversity.

21 Pathogenic bacterial biofilms can be life-threatening, greatly decr

22 (PNAG) is a major structural determinant of bacterial biofilms responsible for persistent and nosoco

23 p. was associated with a substantial loss in bacterial burden and diversity, particularly in the anae

24 Unexpectedly, bacterial burden in prostates challenged with either UPE

25 mucus obstruction, MUC5B protein expression, bacterial burden, and neonatal mortality.

26 ice, and support reduced pathology and lower bacterial burdens in the lung, spleen, and liver.

27 ed a type of Ca(2+) "mini-sensor" in YfkE, a bacterial CAX homolog from Bacillus subtilis.

28 permeabilization of the plasma membrane and bacterial cell death.

29 had no effect upon the polymerization of the bacterial cell division protein FtsZ (a homolog of tubul

30 stress ROS exert on molecular targets at the bacterial cell envelope.

31 ffects on the functionality of gram-negative bacterial cell envelopes.

32 of key divisome proteins, the cornerstone to bacterial cell wall biosynthesis and division.

33 chlorochrysophaentins leads to inhibition of bacterial cell wall biosynthesis by disassembly of key d

34 h E. coli induced pyelonephritis but whether bacterial cell wall constituents inhibit HCO(3) transpor

35 studies that deepen our understanding of how bacterial cell wall enzymes cooperate to build a mature

36 ce of metaphosphates, reported here in whole bacterial cells for the first time, opens the path for f

37 ed by dPCR with appropriately diluted intact bacterial cells from pure cultures, culture-spiked cattl

38 al that fluoresces at these wavelengths, not bacterial cells.

39 In bacterial chemotaxis, each chemoreceptor has multiple me

40 ivation leads to complete destruction of the bacterial chromosome, causing cell death prior to comple

41 ns in the coverage depth between viruses and bacterial chromosomes.

42 ntium-induced colitis, loss of MHCII reduces bacterial clearance by decreasing binding of IgA to comm

43 lipoproteins, may result in reduced hepatic bacterial clearance in the juvenile host with septic sho

44 potential underlying fibrin(ogen)-dependent bacterial clearance.

45 in the adult host through increased hepatic bacterial clearance.

46 severe intestinal inflammation and impaired bacterial clearance.

47 These data help to understand the bacterial co-evolution with phages.

48 nfection with influenza can be aggravated by bacterial co-infections, which often results in disease

49 aps cell death in CRSwNP was associated with bacterial colonization, however, neutrophils were less p

50 virulence functions, including facilitating bacterial colonization, suppression of callose depositio

51 lected pre- and post-application to identify bacterial colony forming units (CFUs) and the percent of

52 rding these distinct microplastic-associated bacterial communities and microplastic uptake pathways i

53 The profiling of bacterial communities by the sequencing of housekeeping

54 Bacterial communities in biofilters can improve drinking

55 Overall diversity of bacterial communities in house dust was similar by asthm

56 d beta (compositional) diversity of airborne bacterial communities, with diversity decreasing roughly

57 All wines harboured complex and variable bacterial communities, with Tatumella as the most abunda

58 rther dysbiotic by the synergistic action of bacterial communities.

59 correlated motions, similar to rafts in many bacterial communities.

60 We found that bacterial community assembly was predictable from linear

61 e importance of variable selection, for soil bacterial community assembly within islands.

62 We explored how bacterial community composition and underlying ecologica

63 sediment bacteria using 16S rRNA sequences, bacterial community composition of a sediment was associ

64 However, the composition of this bacterial community differs considerably between studies

65 d a causal role of a properly assembled leaf bacterial community in phyllosphere health.

66 Bacterial community transplantation experiments demonstr

67 nd species-specific integration in a complex bacterial community.

68 Although the potential to influence bacterial competition is clear, the fitness impacts of w

69 els with smallest error rate for controls in bacterial component and inactive disease in metabolites.

70 onas, Enterobacteriaceae and H(2)S producing bacterial counts were obtained in PEF-1 CLE, compared to

71 o can prematurely terminate transcription of bacterial CRISPR arrays, and we identify a widespread an

72 y immature, insensitive to RORgamma-inducing bacterial cues and to IL6, and showed evidence of higher

73 of 15 bacterial targets compared to routine bacterial culture.

74 ta included antibiotic resistance results of bacterial cultures from hospitalized patients, alongside

75 By using bacterial cultures present in the surroundings or raw ma

76 These alterations rapidly induced bacterial death.

77 n proposed as an effective tool to assist in bacterial decontamination and modulating peri-implant ti

78 Understanding bacterial defense and survival strategies against one of

79 view, we reveal the basic principles of oral bacterial delivery, from internal genetic engineering ap

80 atency duration suggesting a lack of host or bacterial derived mutational stress.

81 ytical performance of ~30 min, the resulting bacterial detection platform was demonstrated to be fast

82 vars resistant to fire blight, a devastating bacterial disease caused by Erwinia amylovora, is a prio

83 n during AA and the control of S. pneumoniae bacterial disease.

84 cruit additional neutrophils in the event of bacterial dissemination to the lymph node.

85 ocalizes on the bacterial surface, assisting bacterial dissemination via proteolysis of host defense

86 Unexpectedly, bacterial diversity (ASV, Faith PD and Shannon) was high

87 maceuticals) under different combinations of bacterial diversity and bedform-induced hyporheic flow u

88 , but red wines were characterized by higher bacterial diversity and increased relative and absolute

89 and severity were negatively associated with bacterial diversity and richness (P < .05).

90 ntal stress on grape integrity, can increase bacterial diversity and specific bacterial taxa in wine,

91 rogs were swabbed for pathogen load and skin bacterial diversity and stimulated to release stored ant

92 We characterized fungal and bacterial diversity within pieces of deadwood that exper

93 etion of Lactobacillus species and increased bacterial diversity, is associated with increased FGT cy

94 ng inflammatory mediators and reduced sputum bacterial diversity.

95 reasing number of studies have reported that bacterial DNA methylation has important functions beyond

96 Bacterial dormancy can take many forms, including format

97 The discovery that one bacterial effector evolved to target ATG16L1's engagemen

98 ur results indicate that CstK functions as a bacterial effector protein that interacts with the host

99 e protein A (OmpA) are essential for optimal bacterial entry into host cells, but their relevance to

100 ing the activity of the C-terminal domain of bacterial Enzyme I (EIC).

101 (MTases) represent a unique opportunity for bacterial epigenomic studies.

102 encoded in previously unidentified putative bacterial exopolysaccharide biosynthetic operons and in

103 More research is needed to identify the bacterial factors involved in clinical presentation and

104 e question of defining the specific host and bacterial factors responsible for gastric tumorigenesis.

105 sistant strains(5), our understanding of the bacterial factors that regulate LPS biogenesis is incomp

106 ed to determine the contribution of host and bacterial factors toward K. pneumoniae dissemination.

107 The rate of cell growth is crucial for bacterial fitness and drives the allocation of bacterial

108 the ability to catabolize L-serine increases bacterial fitness and provides Enterobacteriaceae with a

109 ing the identification of genes that predict bacterial fitness.

110 Our results suggest that bacterial flagella are too straight and too far apart to

111 d human health indicate that modification of bacterial function could be a powerful therapeutic strat

112 in the understanding of chemically mediated bacterial-fungal interrelations.

113 Most studies did not identify or report bacterial/fungal coinfection (85/140; 61%).

114 orine (as chloramine) residual and decreased bacterial gene targets to building inlet concentrations

115 Mean bacterial genome size, GC content, total number of tRNA

116 biosynthesis in a collection of over 10,000 bacterial genomes from both cultured isolates and metage

117 ponsible for triuret decomposition (trtA) in bacterial genomes, clustered with biuH, which encodes bi

118 bly has emerged as an important technique in bacterial genomics, but cost and labor requirements limi

119 Polyphenols affected multiple commensal bacterial groups and showed different synergistic and an

120 ense a diffusible molecule, thereby enabling bacterial groups to coordinate their behavior in a densi

121 d an elevated abundance of genes involved in bacterial growth and division.

122 ng the colder periods when AMP synthesis and bacterial growth is slow and pathogen pressure from this

123 t with lysozyme-functionalized origami slows bacterial growth more effectively than treatment with fr

124 sulfite assimilation, pssm2-Fd complemented bacterial growth when coexpressed with a P. marinus sulf

125 horizontal gene transfer to counter evolving bacterial host defenses; such arms race dynamics should

126 orts to rapidly and comprehensively identify bacterial host factors important in phage infection and

127 ot motile themselves, they can infect motile bacterial hosts and spread in space via the hosts.

128 ing that FSTL-1 influences type-17 pulmonary bacterial immunity.

129 was identified between IA and posttransplant bacterial infection (OR = 7.51; 95% CI = 4.37-12.91), re

130 arker could reliably and rapidly distinguish bacterial infection from other, noninfectious causes of

131 cytosolic double-stranded DNA from viral or bacterial infection in mammalian cells, cyclic dinucleot

132 ls exacerbates macrophage responses to acute bacterial infection in mice, leading to high mortality d

133 e importance and regulation of TRIM21 during bacterial infection remains poorly understood.

134 for diagnostic imaging of obesity/diabetes, bacterial infection, and cancer.

135 eature of pathological states encountered in bacterial infection, inflammation, wounds, cardiovascula

136 on of local mast cells also clears cutaneous bacterial infection, promotes healing, and protects agai

137 l role for FSTL-1 in innate lung immunity to bacterial infection, suggesting that FSTL-1 influences t

138 in genetically programmed susceptibility to bacterial infection.

139 means of nutritional self-medication against bacterial infection.

140 usceptibility of these individuals to severe bacterial infection.

141 r communication for maximizing the spread of bacterial infection.

142 ing an important function of this protein in bacterial infection.

143 trol of macrophage activation in response to bacterial infection.

144 minent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1(l

145 arvae have impaired recruitment to localized bacterial infections and reduced survival that is, at le

146 physiological roles of TCP96 in controlling bacterial infections and reducing LPS-induced inflammati

147 d paper devices for timely identification of bacterial infections at the point-of-care and their usef

148 This leads to more productive intracellular bacterial infections but is protective against malarial

149 phage therapy targeting antibiotic-resistant bacterial infections generally.

150 nary tract infection, one of the most common bacterial infections in humans.

151 resort used in treating multi-drug resistant bacterial infections in humans.

152 prevention strategies against intracellular bacterial infections such as brucellosis.

153 (+) juveniles exhibited spontaneous neonatal bacterial infections with robust mucoinflammatory featur

154 coccus aureus is among the leading causes of bacterial infections worldwide.

155 IRF3 is also involved in resistance to some bacterial infections, in anticancer immunity, and in ant

156 ost defenses and increases susceptibility to bacterial infections.

157 activity was stable in the presence of high bacterial inoculum size compared to vancomycin and fidax

158 low competition reveals distinct modules of bacterial interactions.

159 olymicrobial synergy and dysbiosis model for bacterial involvement in OSCC, with driver mutations gen

160 TrkH is a bacterial ion channel implicated in K(+) uptake and pH r

161 Bacterial iron content depends on the external iron conc

162 thy individuals as well as diverse human gut bacterial isolates were capable of inactivating the iden

163 This serum also induced bacterial killing in opsonophagocytosis assays, suggesti

164 otein kinase, provide the first example of a bacterial kinase that requires IP6 for its activation, a

165 ther via partial dietary restriction or with bacterial l-Met-degrading enzymes exerts potent antitumo

166 nd IL-10 compared with control subjects, and bacterial lactate increases IL-10 production by human mo

167 RNA has revealed the extensive diversity of bacterial life on earth.

168 es of lysogeny among several dominant marine bacterial lineages.

169 Their interactions with gut-derived bacterial lipopolysaccharide (LPS) are implicated in hep

170 a decrease in its activity results in higher bacterial load and exacerbated organ damage, ultimately

171 ation in vitro, and is effective at lowering bacterial load in a mouse model of infection.

172 We measure bacterial load in a non-invasive manner using a lucifera

173 Finally, bacterial loads (colony-forming units per milliliter) in

174 t SAM has a bacterial origin, with increased bacterial loads, reduced diversity and altered compositi

175 While many bacterial mechanisms for overcoming nutritional immunity

176 These discoveries argue that bacterial membrane potential dynamics deserve more atten

177 enhances AMP-induced pores, depolarizes the bacterial membrane potential, and impairs membrane recov

178 FtsH, a bacterial membrane-anchored AAA+ protease, plays a vital

179 h their ability to selectively form pores in bacterial membranes remains elusive.

180 th CNS infections and 16 were diagnosed with bacterial meningitis (8%).

181 We analyzed episodes of community-acquired bacterial meningitis associated with CSF leakage from a

182 Of 2264 episodes of community-acquired bacterial meningitis between 2006 and 2018, 143 (6%) wer

183 ctome expansion over available reconstructed bacterial metabolic networks.

184 ys the groundwork for non-invasive probes of bacterial metabolism and offers prospects for detection

185 eve quantitative and temporal control of gut bacterial metabolism in order to reveal its local and sy

186 to the significant role of sigma factors in bacterial metabolism, their rational engineering for com

187 Herein, we describe bacterial metabolites with known or suspected neuromodul

188 e phylogenetically with, those of coexisting bacterial methanotrophs, including members of Methylopar

189 assembly of the 1,2-propanediol utilization bacterial microcompartment from Salmonella enterica sero

190 e, which is metabolized in a proteome-costly bacterial microcompartment that spatially constrains the

191 cy diminished intestinal immune responses to bacterial molecular patterns and resulted in the expansi

192 he brain and discuss direct effects that gut bacterial molecules are likely exerting on specific brai

193 Moreover, we show that intestinal flow and bacterial motility are potential targets for therapeutic

194 ides in the intricate behaviors coordinating bacterial multicellularity.

195 al populations exhibit antibiotic tolerance, bacterial mutants with higher or lower tolerant subpopul

196 ghput measurement of the relative fitness of bacterial mutants, strains and species in mixed inocula

197 Compared to their mammalian counterparts, bacterial Na(V) channels possess a simpler, fourfold sym

198 f phage therapy targeting infections such as bacterial neonatal meningitis and is an important step f

199 Bacterial neonatal meningitis results in high mortality

200 ctious diseases consultation for an invasive bacterial or fungal infection.

201 insight into the assembly mechanism of these bacterial organelles and will aid downstream engineering

202 Our work therefore supports that SAM has a bacterial origin, with increased bacterial loads, reduce

203 an up-regulate and activate DinB/pol IV, the bacterial ortholog of Polkappa, to induce mutagenesis th

204 d A, MPLA) displayed increased biogenesis of bacterial outer membrane vesicles (OMVs).

205 mmune activation promoted by products of gut bacterial overgrowth/dysbiosis and altered intestinal ba

206 aeruginosa is an extracellular opportunistic bacterial pathogen commonly associated with infectious c

207 lia burgdorferi, the tick-borne Lyme disease bacterial pathogen.

208 in vivo relevance of CP-GAS interactions to bacterial pathogenesis remain unknown.

209 venae, naringenin was more effective against bacterial pathogens and sakuranetin was more effective a

210 re the mechanisms behind phage resistance in bacterial pathogens and the physiological consequences o

211 Streptococcus pneumoniae were the commonest bacterial pathogens detected; atypical bacteria were unc

212 ovide a competitive barrier against invading bacterial pathogens in the intestinal tract, on the skin

213 es, and in particular, several Gram-negative bacterial pathogens including Neisseria meningitidis, Vi

214 Many Gram-negative bacterial pathogens interact with mammalian cells by usi

215 karyotic serine/threonine protein kinases in bacterial pathogens is emerging as an important strategy

216 is and Chlamydia muridarum are intracellular bacterial pathogens of mucosal epithelial cells.

217 cteria, a group of intracellularly surviving bacterial pathogens that includes Mycobacterium tubercul

218 esis of persistence induced by intracellular bacterial pathogens, including B. abortus Results from t

219 me and increases susceptibility to potential bacterial pathogens.

220 lement of the defense of the airways against bacterial pathogens.

221 Methane production reveals an additional bacterial pathway distinct from archaeal methanogenesis.

222 Fragments of bacterial peptidoglycan (muramyl peptides) activate inna

223 wed by challenge with A. phagocytophilum The bacterial peripheral blood burden was pronouncedly reduc

224 Here, examining the invasive bacterial periplasmic predator Bdellovibrio bacteriovoru

225 contribution of these elements to important bacterial phenotypes.

226 a (BChl a), the chief pigment for anoxygenic bacterial photosynthesis, include creating the macrocycl

227 up to 5.25 years later, as an indication of bacterial physiological state and possible generation ti

228 d plants, thus the evolution of AHL-mediated bacterial-plant/algal interactions is unknown.

229 -like or even crystal-like structures in the bacterial plasma membrane and thereby promotes rapid per

230 ndotoxin after successful treatment of donor bacterial pneumonia promotes PGD through ischemia/reperf

231 evels enable the practitioner to distinguish bacterial pneumonia, which requires antibiotic therapy,

232 therapeutic interventions for patients with bacterial pneumonia.

233 Bacterial polymers have important roles in pathogenicity

234 Pel is a GalNAc-rich bacterial polysaccharide that contributes to the structu

235 nd reovirus can be stabilized by bacteria or bacterial polysaccharides, limiting inactivation and aid

236 ed that the acyltransferase selects from the bacterial pool of acyl-acyl carrier proteins (ACPs) an a

237 posed to antibiotics, however, the fate of a bacterial population depends on diverse factors.

238 pling technology and techniques to enumerate bacterial populations and their metabolic products shoul

239 Although all wild-type bacterial populations exhibit antibiotic tolerance, bact

240 ersistence, and inflammatory activity of gut bacterial populations.

241 to form pores by virtue of its similarity to bacterial pore-forming colicins.

242 ed paracellular translocation of bacteria or bacterial products through the small intestinal epitheli

243 Fecal bacterial profile differed between IBS subtypes, while t

244 en IBS subtypes, while the mucosa-associated bacterial profile was associated with IBS symptom severi

245 zed with 16S amplicon sequencing to identify bacterial profiles in young (3 to 7 y) and adult (12 to

246 L, a supervised ML classification to predict bacterial protective antigens (BPAgs).

247 Bacterial resistance to antibiotics in this clinical set

248 cterial fitness and drives the allocation of bacterial resources, affecting, for example, the express

249 Positive bacterial respiratory culture predicted pulmonary dysfun

250 drug-target binding is a major predictor of bacterial responses to antibiotics.

251 The bacterial ribosome is recycled into subunits by two cons

252 One example is the conserved bacterial ribosome silencing factor (RsfS) that binds to

253 Bacterial RNA extracted directly from oropharyngeal swab

254 etermined the X-ray crystal structure of the bacterial RNA polymerase engaged in reiterative transcri

255 Cost-effective bacterial RNA-seq requires efficient physical removal of

256 tom titers of various antibiotics and splits bacterial samples upon a simple syringe injection step t

257 ell shape in V. cholerae is regulated by the bacterial second messenger cyclic dimeric guanosine mono

258 Nanomaterials can play an essential role in bacterial sensing owing to their unique optical, magneti

259 A), urinary tract infection (UTI), and acute bacterial skin and skin structure infection (ABSSSI) do

260 Leupeptin is a bacterial small molecule that is used worldwide as a pro

261 Many bacterial small RNAs (sRNAs) efficiently inhibit transla

262 tential targets for therapeutically managing bacterial spatial organization and inflammatory activity

263 Bacterial specialized metabolites are increasingly recog

264 ples contained genetic material from various bacterial species and the in-depth analysis uncovered th

265 oculum, route of infection and the causative bacterial species in different wild-type mouse backgroun

266 m a ring-like structure, the Z-ring, in most bacterial species.

267 by increasing antibiotic resistance in many bacterial species.

268 e a promising probe for detecting Pse across bacterial species.

269 We report here that the bacterial sRNA SsrA plays an essential role in the light

270 Metagenomic inferences of bacterial strain diversity and infectious disease transm

271 The emergence of multi-drug-resistant bacterial strains further complicates patient treatment.

272 hPm localizes on the bacterial surface, assisting bacterial dissemination via

273 goes undetected in the clinic, may allow for bacterial survival and establishment of a reservoir for

274 nt work that suggests that H(2)S/RSS impacts bacterial survival in infected cells and animals.

275 y invasive species that harbours the primary bacterial symbiont 'Candidatus Pantoea carbekii'.

276 This study reveals the potential for a bacterial symbiont's sRNAs not only to control its own a

277 ation involving sigma(54) differs from other bacterial systems, and yields bursting kinetics characte

278 The BFPP identified a viral or bacterial target in 117/200 (58.5%) samples, including S

279 ilus influenzae in 14%, and both a viral and bacterial target in 4% of samples.

280 ce crisis, there is an urgent need for novel bacterial targets and antibiotics with novel modes of ac

281 PA) for the qualitative identification of 15 bacterial targets compared to routine bacterial culture.

282 to measure absolute abundances of individual bacterial taxa by combining the precision of digital PCR

283 an increase bacterial diversity and specific bacterial taxa in wine, with potential consequences for

284 actic and acetic acid bacteria (LAB/AAB) and bacterial taxa of predicted environmental origin.

285 scent in situ hybridization for 10 different bacterial taxa.

286 a safe agent (as they cannot replicate) for bacterial therapy.

287 ssing UP strain, and post-mortem by qPCR and bacterial titration.

288 bioinformatics pipelines for the analysis of bacterial transcriptomic data commonly ignore non-coding

289 nucleoside tetraphosphate (Np(4)) capping of bacterial transcripts.

290 Antibiotic use and bacterial transmission are responsible for the emergence

291 Mutational analysis, combined with bacterial two-hybrid screens and in vivo functional assa

292 Bacterial type VII secretion systems secrete a wide rang

293 roS is functionally different from canonical bacterial UroS proteins.

294 need for new treatments to prevent recurrent bacterial vaginosis.

295 llular proteins that play important roles in bacterial viability and in interactions of pathogenic my

296 ia is a multilayered structure essential for bacterial viability; the peptidoglycan cell wall provide

297 nfection in germ-free mice to show that live bacterial virulence factor-driven immunogenicity can be

298 e we add that arginine also directly impacts bacterial virulence.

299 the roles of upregulated regulatory genes in bacterial virulence.

300 Above the critical bacterial volume fraction needed to decrease the viscosi