ライフサイエンスコーパス: bacteriocin

1 minosarum and was previously known as 'small bacteriocin'.

2 ain via secretion of surfactants and a toxic bacteriocin.

3 he antimicrobial activity of the full-length bacteriocin.

4 The second is resistant to the bacteriocin.

5 lactosylation alters L. lactis resistance to bacteriocin.

6 mately 20 kDa, termed dendritiformis sibling bacteriocin.

7 chromosomal locus for lactacin B, a class II bacteriocin.

8 an Erwinia carotovora carotovoricin Er-like bacteriocin.

9 in altering host specificity for a putative bacteriocin.

10 genotype or resistance to metronidazole and bacteriocin.

11 enotype, and resistance to metronidazole and bacteriocin.

12 ity, and thus behaves as a contact-dependent bacteriocin.

13 roduced antimicrobial peptide from class IIa bacteriocins.

14 rent kinds of lantibiotic and nonlantibiotic bacteriocins.

15 cks and thereby reveal the full potential of bacteriocins.

16 rse family of microbial defense systems: the bacteriocins.

17 ts, numerous types of protein exotoxins, and bacteriocins.

18 is of class I (lantibiotic) or some class II bacteriocins.

19 produce small antibacterial peptides called bacteriocins.

20 s in situ, including several uncharacterized bacteriocins.

21 categories-antimicrobial, antibacterial and bacteriocins.

22 SS); contact dependent inhibition (CDI); and bacteriocins.

23 systems, insecticidal protein complexes, and bacteriocins.

24 y and for protection against exogenous DNase bacteriocins.

25 e of the conjugative plasmid pPD1 expressing bacteriocin 21 in enterococcal colonization.

26 Bacteriocin 41 (Bac41) is produced by certain E. faecali

27 otein D (CbpD) and on the competence-induced bacteriocins A and B (CibAB) implicated in fratricide.

28 ablishes that the thiopeptides are a type of bacteriocin, a family of genetically encoded antimicrobi

29 bacteria can kill nearby cells by secreting bacteriocins, a diverse group of proteinaceous antimicro

30 that usually mediates translocation of these bacteriocins across the outer membrane, containing only

31 e recombinant BacL1 and BacA showed complete bacteriocin activity against E. faecalis, but neither Ba

32 n the Bac41 operon, coordinately express the bacteriocin activity against E. faecalis.

33 nt type 19A background was deficient in both bacteriocin activity and immunity.

34 mportantly, bile acids strongly enhance this bacteriocin activity in vivo, leading to greater SGG col

35 ther BacL1 nor BacA protein alone showed the bacteriocin activity.

36 a, a distribution inconsistent with putative bacteriocin activity.

37 t as is found for colicin Ia, these H. alvei bacteriocins (alveicins) lack lysis genes.

38 level constitutive expression system for the bacteriocin and immunity genes of channel-forming colici

39 s (PCATs) export amphipathic and hydrophilic bacteriocin and quorum-sensing proteins across the membr

40 s a transcription activator for a variety of bacteriocins and bacteriocin-related genes.

41 artial unfolding of TolAIII, suggesting that bacteriocins and bacteriophages parasitize E. coli using

42 ribution of the blp locus, encoding putative bacteriocins and cognate immunity peptides, to intraspec

43 We provide a novel dataset of predicted bacteriocins and context genes.

44 egulated genes associated with production of bacteriocins and downregulated colonization-associated g

45 he phenotypic characteristics, production of bacteriocins and H2O2 are regulated by environmental con

46 isms to protect their cell envelopes against bacteriocins and host cationic antimicrobial peptides (C

47 ltifunctionality of FepA: toxic ligands like bacteriocins and phage penetrate the outer membrane by p

48 alis, disulfide bonds are formed in secreted bacteriocins and required for activity.

49 han immunity proteins, which protect against bacteriocins and suggest that these bacterial weapons ar

50 XIP to stimulate production of antimicrobial bacteriocins and to induce development of competence for

51 sequence within the central domain of these bacteriocins and to involve residues present in the shor

52 etitors, via the release of chemicals (e.g., bacteriocins ) and via the release of parasites (e.g., t

53 Bacterial toxins (e.g. bacteriocins) and viruses (bacteriophages) targeting Gra

54 embeddings of protein sequences to represent bacteriocins, and apply a word embedding method that acc

55 These bacteriocins appear to be chimeras consisting of translo

56 and the expression of virulence factors and bacteriocins are all controlled by this important transc

57 Bacteriocins are an abundant class of antimicrobial mole

58 Bacteriocins are antimicrobial peptides that are natural

59 one-responsive conjugative plasmids encoding bacteriocins are common among enterococcal strains and c

60 Recent discoveries have shown that bacteriocins are highly diverse and widely distributed a

61 r-binding parts of LsbB and sequence-related bacteriocins are located in their C-terminal halves.

62 R-type bacteriocins are minimal contractile nanomachines that h

63 Bacteriocins are peptide-derived molecules produced by b

64 The colicin-like bacteriocins are potent protein antibiotics that have ev

65 Among the AMP molecules, bacteriocins are produced by both gram-positive and gram

66 ates for context genes which may clarify how bacteriocins are synthesized, and identify new candidate

67 However, bacteriocins are typically freely diffusible, and so of

68 e the fact that closely related colicin-like bacteriocins are widely produced by Gram-negative bacter

69 Finally, we show that several E. coli bacteriocins are widely shared with the pathogen Salmone

70 Protein antibiotics, known as bacteriocins, are widely produced by bacteria for intras

71 ce element sufficient for the binding of the bacteriocin as well as of hybrid indicator proteins to t

72 acteriocin diversity observed and the use of bacteriocins as preservatives in the food industry and a

73 Enzymatic modification of bacteriocins as well as their export is achieved by prot

74 otal synthesis of the three largest circular bacteriocins, AS-48, uberolysin, and garvicin ML, by an

75 ssociator (BOA) that can identify homologous bacteriocin associated gene blocks and predict novel one

76 lling phenotypes revealed two instances of a bacteriocin associated with a bacteriophage gene, the fi

77 from chicken gizzard, was noted to produce a bacteriocin (BacJ1) that inhibited Gram-positive and Gra

78 pacity to colonize human epithelia, owing to bacteriocin-based bacterial interference.

79 Bacteriocin becomes a promising antimicrobial agent to f

80 ulence factors, and in several regulators of bacteriocin biosynthesis, previously unified in the AgrA

81 pology of the nisin pathway for constitutive bacteriocin biosynthesis.

82 nine-gene GAS locus (sagA-sagI) resembling a bacteriocin biosynthetic operon is necessary and suffici

83 re reductions from steric hindrance when the bacteriocin bound to the receptor protein.

84 not due to expression of a lantibiotic-type bacteriocin, but proteolytically processed derivatives o

85 However, the discovery of new bacteriocins by genomic mining is hampered by their sequ

86 Bacillus subtilis produces an anionic bacteriocin called subtilosin A that possesses antibacte

87 Steinernema carpocapsae, produces the R-type bacteriocin called xenorhabdicin, which is thought to co

88 a family of ribosomally synthesized peptide bacteriocins called lantibiotics (lanthionine-containing

89 ion of a variable repertoire of pneumococcal bacteriocins called pneumocins and their associated immu

90 biotherapeutic products (eLBPs) that secrete bacteriocins can be created to deliver targeted bacterio

91 Thus, just as bacteriocins can lead to increased diversity via rock-pa

92 Some of these compounds, such as bacteriocins, can affect bacteria of similar or closely

93 id-containing host also produces gelatinase, bacteriocin cannot be detected.

94 y highlights that short peptide ligands from bacteriocin class offer high selectivity in bacterial de

95 nslocation domain (IUTD) of the endonuclease bacteriocin ColE9 is imported passively across the Esche

96 We have studied how the bacteriocin colicin E9 (ColE9) assembles a cytotoxic tra

97 e outer membrane protein TolC constitute the bacteriocin colicin V secretion system in Escherichia co

98 by the C-terminal pore-forming domain of the bacteriocin, colicin E1.

99 the lethal, channel-forming activity of the bacteriocin, colicin E1.

100 ailed studies into the biosynthesis of other bacteriocin compounds and the production of these natura

101 Given the heterogeneity of bacteriocin compounds, many tools struggle with identify

102 le Hidden Markov Models from the clusters of bacteriocin context genes, and uses them to identify nov

103 by members of the domain Bacteria: circular bacteriocins, cyanobactins, and circular pilins.

104 llows users to search peptide families (e.g. bacteriocins, cyclotides, or defensins), peptide sources

105 mpetition in the gastrointestinal tract, and bacteriocins, delivered by commensals that occupy a prec

106 results therefore identify LLS as the first bacteriocin described in L. monocytogenes and associate

107 d almost a century ago, our understanding of bacteriocin distribution and prevalence in bacterial pop

108 ecular mechanisms involved in the process of bacteriocin diversification.

109 vide a novel mechanism for the generation of bacteriocin diversity in Klebsiella.

110 sing attention because of the high levels of bacteriocin diversity observed and the use of bacterioci

111 f clinical isolates suggested that the BlpMN bacteriocins divide into two families.

112 Unlike T6SS and CDI systems, bacteriocins do not require contact between bacteria but

113 , many tools struggle with identifying novel bacteriocins due to their vast sequence and structural d

114 Bacteriocins elaborated by S. mutans, termed mutacins, m

115 Bacteriocin encoding genes are frequently found in micro

116 f mutations in antimicrobial resistance- and bacteriocin-encoding genes.

117 The complete nucleotide sequences of two bacteriocin-encoding plasmids isolated from Hafnia alvei

118 t here the identification of the E. faecalis bacteriocin, EntV, produced from the entV (ef1097) locus

119 sequence homology with five other leaderless bacteriocins, especially at their C-terminal halves wher

120 Therefore, bacteriocin expression by commensal bacteria can influen

121 ighly modified peptides that are part of the bacteriocin family of antimicrobial peptides.

122 products suggest that SLS is related to the bacteriocin family of microbial toxins.

123 an be used to discover new highly dissimilar bacteriocins for developing highly effective antibiotic

124 achinery to synthesize antibiotic molecules (bacteriocins) for their continuous warfare with other mi

125 It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from

126 order in protein sequences, to predict novel bacteriocins from protein sequences without using sequen

127 An SGG-specific locus encoding a bacteriocin ("gallocin") is shown to kill enterococci in

128 ntext genes, and uses them to identify novel bacteriocin gene blocks and operons.

129 Exogenous XIP increases the expression of bacteriocin gene clusters and produces an antimicrobial

130 rsR binds to the promoter regions of several bacteriocin genes and requires the presence of a LytTR f

131 gulator, BlpR, and requires the two putative bacteriocin genes blpM and blpN.

132 t several phyla have a strong preference for bacteriocin genes, suggesting distinct functions for thi

133 The bacteriocin haemocin is produced by most type b strains

134 The first gene to encode a haloarchaeal bacteriocin (halocin H4) has been cloned and sequenced f

135 r binding and species specificities of these bacteriocins has been driven by diversifying selection r

136 One class of antimicrobials, the bacteriocins, has received increasing attention because

137 To date, close to five hundred bacteriocins have been identified and classified.

138 treatment both bacteriophage endolysins and bacteriocins have been shown to possess antimicrobial ef

139 Recently, bacteriocins have even been used to treat cancer.

140 broad-spectrum antimicrobial activity, some bacteriocins have the potential of becoming the next gen

141 i-viral metabolites such as a homolog of the bacteriocin helveticin-J were found.

142 esent in a subset of lineage I strains, is a bacteriocin highly expressed in the intestine of orally

143 hat the inactivation of bip or smbG, another bacteriocin immunity protein gene present within the smb

144 ies resulted from repression of the putative bacteriocin immunity protein gene, bip, which is located

145 s of these observations for the evolution of bacteriocin immunity protein genes as well as for potent

146 ium can be modulated by some of the putative bacteriocin immunity proteins expressed by the organism.

147 encoding homologs of dendritiformis sibling bacteriocin in other bacterial species suggests that thi

148 s of TxeR regulate synthesis of toxins and a bacteriocin in other Clostridium species, TxeR appears t

149 Here, we identify an atypical two-protein bacteriocin in the alpha-proteobacterium Caulobacter cre

150 Production of R-type bacteriocins in a host organism had not been shown previ

151 a high probability, six yet unknown putative bacteriocins in Lactobacillus.

152 All bacteriocins in this family have a conserved N-terminal

153 kin, as in poison-antidote systems, such as bacteriocins, in which cells benefit their own kind by p

154 m the C-terminal regions of two LsbB-related bacteriocins inhibited the activity of LsbB, in the same

155 for the penetration of several nuclease-type bacteriocins into target cells.

156 Bacteriocin is an important peptide which can be used as

157 Uptake of the bacteriocin is required for activity in the periplasm le

158 f adaptive prophage-derived elements such as bacteriocins, killer particles, gene transfer agents, or

159 t C. difficile-killing spectrum, with no one bacteriocin killing all C. difficile isolates tested.

160 pathogen that produces a powerful cytolytic bacteriocin known as streptolysin S (SLS).

161 stance, the ribosomally produced siderophore bacteriocins, known as class IIb microcins, affect the c

162 we show that Pseudomonas aeruginosa specific bacteriocins, known as pyocins, show strong efficacy in

163 This unusual bacteriocin lacks the intrinsically unstructured translo

164 n responsible for the synthesis of the novel bacteriocin lacticin 3147; and (iii) the phage resistanc

165 Lacticin 481 is a lanthionine-containing bacteriocin (lantibiotic) produced by Lactococcus lactis

166 trate was developed for direct recovery of a bacteriocin-like inhibitory substance (BLIS) from a cult

167 on was employed for the first time to purify bacteriocin-like inhibitory substance (BLIS) from a ferm

168 oduce a low-molecular-weight, broad-spectrum bacteriocin-like inhibitory substance (BLIS).

169 A new gene, sboX, encoding another bacteriocin-like product was discovered residing in a se

170 The bacteriocin-like proteins CdzC and CdzD harbor glycine-z

171 The product of the tail fiber ORF in the bacteriocin-like region shows a hybrid structure where t

172 peptide supports the designation of SLS as a bacteriocin-like toxin.

173 importance of tailoring nano-DDS to address bacteriocin limitations, the successes and failures of t

174 Here, we report the discovery of a Listeria bacteriocin, Lmo2776, which limits Listeria intestinal c

175 phage endolysin CHAPK and the staphylococcal bacteriocin lysostaphin have been co-administered in a t

176 f this review we focus on the potential role bacteriocins may play in addressing human health concern

177 nd show that colicins (and potentially other bacteriocins) may promote, rather than eliminate, microb

178 The Enterococcus faecalis class IIa bacteriocin MC4-1 encoded by the sex pheromone-respondin

179 For a consortium of bacteriocin-mediated cooperation and competition, we fin

180 This is similar to previously described bacteriocin-mediated effects.

181 gg/RNPP regulator ComR couples competence to bacteriocin-mediated predation.

182 ture antibiotics, some of the tricks used by bacteriocins might be exploited for the synthesis of nov

183 competence system and the expression of the bacteriocin mutacin IV of S. mutans, as well as the H(2)

184 nd measure expression of nlmAB (encoding the bacteriocin mutacin IV) within mice to assess its import

185 gate the requirement for ComE to produce the bacteriocin mutacin IV.

186 Production of the bacteriocin, mutacin I, is one such mechanism.

187 The mutant bacteriocin, named subtilosin A1, has a replacement of t

188 s in order to improve the next generation of bacteriocin nano-sized drug delivery systems (Nano-DDS).

189 The antimicrobial activity of the resultant bacteriocin-nanoclay systems was analyzed using skimmed

190 ov Models for the identification of nuclease bacteriocins (NBs) in bacteria of which, to-date, only a

191 actococcus lactis produce the broad-spectrum bacteriocin nisin, which belongs to the lantibiotic clas

192 LsbB is a class II leaderless lactococcal bacteriocin of 30 amino acids.

193 The bacteriocins of Escherichia coli have served as a model

194 Bacteroidetocins are related to class IIa bacteriocins of Gram-positive bacteria and kill members

195 Pyocins, bacteriocins of P. aeruginosa, are potent and diverse pr

196 se goals, we have developed a software tool, Bacteriocin Operon and gene block Associator (BOA) that

197 mobilization genes, as well as colicin-like bacteriocin operons.

198 SH3b domains from either lysostaphin (bacteriocin) or LysK (phage endolysin) resulted in a app

199 This novel bacteriophage/bacteriocin organization may provide a novel mechanism f

200 These R-type bacteriocin particles, which have been purified from dif

201 e, we identify a novel ferredoxin-containing bacteriocin pectocin P, which possesses a cytotoxic doma

202 tructurally characterized the colicin M-like bacteriocin, pectocin M2, which is active against strain

203 Bacteriocin peptides are weapons of inter-bacterial warf

204 f Yersinia pestis confers sensitivity to the bacteriocin, pesticin, and is an integral component of a

205 ere also sensitive to the Y. pestis-produced bacteriocin, pesticin.

206 y addressing these limitations and improving bacteriocin pharmacokinetics and pharmacodynamics.

207 pAD1 is a 60-kb hemolysin-bacteriocin plasmid in Enterococcus faecalis that encode

208 y produced antimicrobial peptides (AMPs), or bacteriocins, play key roles in shaping microbial commun

209 reptococcus pneumoniae encodes a two-peptide bacteriocin, pneumocin MN, which mediates intraspecies c

210 d in a discrete gene cluster proximal to the bacteriocin precursor gene, referred to as context genes

211 all peptides with structural similarities to bacteriocin precursor polypeptides.

212 BaPreS is a bacteriocin prediction tool that can be used to discover

213 The two bacteriocin prediction tools, BAGEL3 and BACTIBASE, both

214 However, bacteriocins present a few drawbacks, such as sensitivit

215 o expand this large CPBP (CAAX proteases and bacteriocin-processing enzymes) family to include more t

216 Plantaricin C, a bacteriocin produced by a Lactobacillus plantarum strain

217 Microcin E492 (Mcc), a low molecular weight bacteriocin produced by Klebsiella pneumoniae RYC492, ha

218 a gonorrhoeae WS1 is a spontaneous pyocin (a bacteriocin produced by Pseudomonas aeruginosa)-resistan

219 Colicin E1 is a bacteriocin produced by, and lethal to, Escherichia coli

220 Among them, bacteriocins produced by lactic acid bacteria stand out

221 hydrolases governing cell division and from bacteriocins produced by microbial competitors.

222 l-regulated production of chemicals, such as bacteriocins (produced by S. mutans) and hydrogen peroxi

223 For self-protection, a bacteriocin producer strain must possess one or more cog

224 During a screening programme for bacteriocin producers, a new lactic acid bacterium calle

225 experiments to verify the importance of key bacteriocin-producing plasmids for clone success.

226 e associated with determinants implicated in bacteriocin production and acid tolerance.

227 In Streptococcus mutans, both competence and bacteriocin production are controlled by ComC and the Co

228 Neither strain competition via bacteriocin production nor biofilm formation showed any

229 ng a 16-gene Tra (transfer) operon; (ii) the bacteriocin production region, including an operon respo

230 biofilm, may utilize the competence-induced bacteriocin production to acquire transforming DNA from

231 each other and ultimately determine whether bacteriocin production will inhibit competitor organisms

232 xtracellular DNA release, biofilm formation, bacteriocin production, and genetic competence.

233 s, mutants in acid tolerance, and mutants in bacteriocin production, at frequencies ranging from 0.1

234 ofilm formation, escape from phagolysosomes, bacteriocin production, toxin activity and protection fr

235 teriocins can be created to deliver targeted bacteriocin production.

236 , biofilm formation, genetic competence, and bacteriocin production.

237 mulating peptide (CSP) to stimulate mutacin (bacteriocin) production and competence development throu

238 Bacteriocin proteins evolved to exploit the accessible,

239 Phage tail-like bacteriocins (PTLBs) are widespread in bacteria, compris

240 as aeruginosa is hijacked to translocate the bacteriocin pyocin S2 (pyoS2) across the outer membrane

241 This bacteriocin (pyocin) that we have named PaeM was crystal

242 Circular bacteriocins, ranging from 35 to 70 amino acids, are the

243 and their prokaryotic homologs with putative bacteriocin-related functions.

244 well as several restriction/modification and bacteriocin-related genes and a number of open reading f

245 activator for a variety of bacteriocins and bacteriocin-related genes.

246 eral stress-related genes and genes encoding bacteriocin-related peptides and many transcription fact

247 Bacteriocins represent a large family of ribosomally pro

248 a seven-gene operon (alb, for antilisterial bacteriocin) residing immediately downstream from the sb

249 mmunogenicity issues, and the development of bacteriocin resistance by pathogenic bacteria.

250 of megaplasmid pSsal-K12, which encodes the bacteriocins salivaricin A and salivaricin B; however, i

251 Colicin-like bacteriocins show potential as next generation antibioti

252 e associated with mobile genetic element and bacteriocins, showed changes in frequency post-PCV.

253 e strains and can therefore be classified as bacteriocins, similar to the R-type pyocins of Pseudomon

254 es resistance to the SPbeta prophage-encoded bacteriocin sublancin, and the yknWXYZ operon and yfhL p

255 n contains sboA, the structural gene for the bacteriocin subtilosin, and the alb genes required for s

256 confirmed that the substance was the cyclic bacteriocin subtilosin.

257 lus subtilis 168 derivative JH642 produces a bacteriocin, subtilosin, which possesses activity agains

258 bset of commensal bacterial strains secretes bacteriocins, such as lantibiotics, to inhibit or kill n

259 The potency and targeted action of bacteriocins suggests that they could be developed into

260 structure and function of the colicin M-like bacteriocin, syringacin M from Pseudomonas syringae pv.

261 Bacteriocin T8 carriage was also strongly associated wit

262 yses revealed that emergent lineages encoded bacteriocin T8, which conferred a competitive advantage

263 which conferred a competitive advantage over bacteriocin T8-negative strains in vitro and upon coloni

264 anisms for inhibiting competitors, including bacteriocins, tailocins, type VI secretion systems and c

265 cell-killing that is generally not found in bacteriocins targeting the periplasm, implying a specifi

266 A bacteriocin termed SRCAM 602 previously reported to be p

267 are related to the rapidly growing class of bacteriocins termed lantibiotics.

268 bv. staphylolyticus secretes lysostaphin, a bacteriocin that cleaves pentaglycine cross bridges in t

269 confer resistance to lysostaphin, a secreted bacteriocin that cleaves the pentaglycine cross-bridge.

270 Colicin N is a pore-forming bacteriocin that enters target Escherichia coli cells wi

271 Enterocin K1 (EntK1), a bacteriocin that is highly potent against vancomycin-res

272 distribution of host interaction factors and bacteriocins that affect their natural and industrial en

273 synthesized, and identify new candidates for bacteriocins that bear no sequence similarity to known t

274 le of entering a suicidal program to release bacteriocins that kill other bacteria.

275 type pyocin particles have been described as bacteriocins that resemble bacteriophage tail-like struc

276 The colicins are bacteriocins that target Escherichia coli and kill bacte

277 Colicins are Escherichia coli-specific bacteriocins that translocate across the outer bacterial

278 It belongs to a family of bacteriocins that, when membrane-associated, is predicte

279 utolysis-related genes and those that encode bacteriocins, the ClpB protease chaperone subunit, pyruv

280 However, paradoxically, import of protein bacteriocins, the mechanisms of which are poorly underst

281 Although bacteriocins themselves are structurally diverse, contex

282 In the case of protein bacteriocins, this is because of high levels of sequence

283 s, the CWT domain of lysostaphin directs the bacteriocin to cross-linked peptidoglycan, which also se

284 in is required for selective binding of this bacteriocin to S. aureus cells; however, the molecular t

285 porins form in the OM are also exploited by bacteriocins to translocate into cells by a poorly under

286 ria often secrete diffusible protein toxins (bacteriocins) to kill bystander cells during interbacter

287 ed approach using nisin, a FDA-approved safe bacteriocin, to inhibit outgrowth of germinated spores a

288 nsure the proper extracellular activation of bacteriocin toxicity.

289 ng phenotypes that suggest the production of bacteriocin toxins.

290 Many bacteriocins undergo post-translational processing or mo

291 This isolated domain of the PaeM bacteriocin was further shown to kill E. coli cells when

292 , proteases, and leukotoxins, in addition to bacteriocins, was transferrable in vitro to human and an

293 Bacteriocins were intercalated into the interlayer space

294 is mutacin (mutacin IV) is a non-lantibiotic bacteriocin which kills closely related Streptococcal sp

295 Bacteriocins, which are bacterially produced antimicrobi

296 ial interactions often rely on antimicrobial bacteriocins, which attack only a narrow range of target

297 AS-48 is a bacteriocin with potential application as food biopreser

298 engineering approaches for obtaining anionic bacteriocins with enhanced and/or altered bactericidal a

299 Thus, combining bacteriocins with nano-DDS may be useful in overcoming t

300 ld make alveicin B the smallest pore-forming bacteriocin yet discovered.