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1 ake them suitable as an appropriately marked balancer.
2 ertions that are useful as dominant, genetic balancers and a set of lacO insertions to track genome p
4 s on the basis of their position relative to balancer breakpoints, leading to a broad distribution of
7 ulator of Polo kinase,(3)(,)(4) with the TM3 balancer chromosome creates a driving genotype that is p
8 we present GRIBCG (Guide RNA Identifier for Balancer Chromosome Generation), a tool for the rational
10 Here we describe the engineering of a mouse balancer chromosome with the Cre-loxP recombination syst
12 through males and made homozygous by using a balancer chromosome, most of the resulting stocks develo
13 y in descendants of a structurally identical balancer chromosome, we sequenced a panel of laboratory
16 mutation accumulation experiments involving balancer chromosomes (set I) or inbred lines (set II).
17 clonal mode for the laboratory evolution of balancer chromosomes and have implications for how balan
23 nation system, we have constructed two mouse balancer chromosomes carrying 8- and 30-cM inversions be
24 osomes were maintained as heterozygotes with balancer chromosomes for >100 generations before screeni
25 te their widespread use, the organization of balancer chromosomes has not been characterized at the m
27 er chromosomes and have implications for how balancer chromosomes should be used in the design and in
29 ags both rearrangements, which enables these balancer chromosomes to be visibly tracked in mouse stoc
30 Our study has implications for the use of balancer chromosomes to maintain mutant lines and provid
32 propriately marked inversions can be used as balancer chromosomes to recover and maintain mutations i
43 ssive, lethal inversion Rump White (Rw) as a balancer in a three-generation breeding scheme to identi
44 play an important physiological role as a pH balancer in the maintenance of H(+) homeostasis in C. el
47 ancers to the previously reported Trp53-Wnt3 balancer, most of mouse chromosome 11 is now available i
49 where TTP, in alliance with TRAF2, acts as a balancer of JNK-mediated cell survival versus death.
50 the Ly-6 superfamily have been implicated as balancers of activity and survival in the adult nervous