ライフサイエンスコーパス: basolateral surface

1 were infected when virus was applied to the basolateral surface.

2 of cell polarity or increased access to the basolateral surface.

3 uptake from the apical surface than from the basolateral surface.

4 arized targeting of membrane proteins to the basolateral surface.

5 y epithelia first released adenovirus to the basolateral surface.

6 cycling of transferrin from endosomes to the basolateral surface.

7 culovirus entry may require contact with the basolateral surface.

8 y cells, CAR is expressed exclusively on the basolateral surface.

9 er penetration of the epithelium through the basolateral surface.

10 e polarized distribution of receptors on the basolateral surface.

11 eate a more efficient budding process at the basolateral surface.

12 re not involved in receptor retention on the basolateral surface.

13 IFN, facilitates antigen processing from the basolateral surface.

14 ved in transporting membrane proteins to the basolateral surface.

15 via class II molecules was restricted to the basolateral surface.

16 t vesicles destined for either the apical or basolateral surface.

17 egraded are selectively recycled back to the basolateral surface.

18 with BCC virus either through the apical or basolateral surface.

19 ese cells, and the protein is present at the basolateral surface.

20 surface was approximately twice that of the basolateral surface.

21 27-kDa heat shock protein exclusively to the basolateral surface.

22 ect delivery to both the apical (60-75%) and basolateral surface.

23 f receptors are selectively delivered to the basolateral surface.

24 A to the apical surface and recycling to the basolateral surface.

25 complex and leads to their missorting to the basolateral surface.

26 ection was not dependent on infection of the basolateral surface.

27 sorting of a broader range of cargoes to the basolateral surface.

28 that of MUC1 were delivered primarily to the basolateral surface.

29 sion of exc-5 causes defects at the tubule's basolateral surface.

30 s, and its expression is concentrated on the basolateral surface.

31 icrotubule-associated, as it migrates to the basolateral surface.

32 arized HIE monolayers preferentially via the basolateral surface.

33 dye FM4-64 when the dye is presented to the basolateral surface.

34 g interaction of selected mediators with the basolateral surface.

35 causes apical proteins to relocalize to the basolateral surface.

36 dIns(3,4,5)P3 regulates the formation of the basolateral surface.

37 infection at the apical surface than at the basolateral surface.

38 his chimera was exclusively localized to the basolateral surface.

39 surface to exhibit increased delivery to the basolateral surface.

40 The highly related syntaxin 4 is at the basolateral surface.

41 onolayers of polarized cells with apical and basolateral surfaces.

42 PAR-1 and PAR-2, redistribute to the inner, basolateral surfaces.

43 anchor are expressed on both the apical and basolateral surfaces.

44 endocytosis and is present on the apical and basolateral surfaces.

45 and that they are active on both apical and basolateral surfaces.

46 used for independent perfusion of apical and basolateral surfaces.

47 mically and functionally separate apical and basolateral surfaces.

48 e trans-Golgi network to both the apical and basolateral surfaces.

49 extensive trafficking between the apical and basolateral surfaces.

50 utant, it was reduced on both the apical and basolateral surfaces.

51 ytosis of cell-free virus from the apical to basolateral surfaces.

52 also requires downward contraction along the basolateral surfaces.

53 irectionally released on the apical, but not basolateral, surface.

54 was optimal if cells were infected at their basolateral surface, a phenomenon associated with the di

55 himurium can infect epithelial cells via the basolateral surface after breaching the intestinal epith

56 llular Ca(2+) at the apical surface, but not basolateral surface, also prevented tight junction disru

57 apical surface and endocytosis of IgA at the basolateral surface, although an antibody against the in

58 meras are then rapidly internalized from the basolateral surface and a significant fraction ( approxi

59 ally applied adenovirus gained access to the basolateral surface and enhanced gene transfer.

60 ta1 subunit was localized exclusively to the basolateral surface and resulted in partial redistributi

61 ds on dIgA binding to the pIgR solely at the basolateral surface and the ability of pIgR to dimerize.

62 Particles are released from the apical and basolateral surfaces and are indistinguishable, indicati

63 s including the induction of lamellipodia at basolateral surfaces and formation of an increased numbe

64 xpressed in rabbit CE on both the apical and basolateral surfaces and function to transport lactate-H

65 onic epithelial cells, Jak3 redistributed to basolateral surfaces and interacted with adherens juncti

66 ial cells, EGFR is restricted largely to the basolateral surface, and apical or basolateral ligand de

67 xpression was more on the apical than on the basolateral surface, and this effect was more pronounced

68 staining was polarized and restricted to the basolateral surfaces, and in contrast to the epithelial

69 aces, extend lamellipodia-like structures at basolateral surfaces, and show disorganization of cell-c

70 to possess Na,K-ATPase exclusively at their basolateral surfaces; apical labeling was not detected.

71 w that APP-TR chimeras internalized from the basolateral surface are found in tubulo-vesicular endoso

72 In epithelia, distinct apical and basolateral surfaces are maintained by tight junctions t

73 The alpha2CAR also is enriched on the basolateral surface at steady-state and, like the alpha2

74 These results were further confirmed by basolateral surface biotinylation.

75 In contrast, all basolateral surface-bound Cbl was internalized and retai

76 EGF added to the basolateral surface but not apical surface of Caco-2/NHE

77 -length proteins were first delivered to the basolateral surface but then concentrated in the apical

78 or (SPI-I) was not required to enter via the basolateral surface but to promote another virulence-ass

79 -TR chimeras are selectively targeted to the basolateral surface by a tyrosine-dependent sorting sign

80 tion is subsequently established through the basolateral surface by infected lymphocytes.

81 selective and regulated flux from apical to basolateral surfaces by transcellular passage through ce

82 Ectopic PtdIns(4,5)P2 at the basolateral surface causes apical proteins to relocalize

83 d cell vacuolation when interacting with the basolateral surface compared to the apical surface.

84 that preferential ectodomain cleavage at the basolateral surface contributes to apical domain localiz

85 l cells, sorting of membrane proteins to the basolateral surface depends on the presence of a basolat

86 reatment with EGTA to increase access to the basolateral surface did not increase transduction of api

87 TLR9 activation through apical and basolateral surface domains have distinct transcriptiona

88 at least two vectorial routes to apical and basolateral surface domains.

89 plasma membrane (PM) proteins to apical and basolateral surface domains.

90 After infection from the basolateral surface, epithelial damage and large cluster

91 to ensure delivery of the transporter to the basolateral surface, especially at high levels of protei

92 ertion of the alpha2BAR into both apical and basolateral surfaces followed by selective retention on

93 contrast, when the virus was applied to the basolateral surface, gene transfer was much more efficie

94 targeting membrane proteins to the apical or basolateral surfaces have remained elusive.

95 ially transduces human airway cells from the basolateral surface; however, virus release remains in a

96 elivery of newly synthesized proteins to the basolateral surface in polarized epithelial cells.

97 ependent biosynthetic sorting pathway to the basolateral surface in polarized epithelial cells.

98 d not reduce the expression on the apical or basolateral surface in polarized Madin-Darby canine kidn

99 helial cells occurred predominantly from the basolateral surface in polarized monolayers of Caco-2 ce

100 ha2ARs) are localized to and function on the basolateral surface in polarized renal epithelial cells

101 egulates early steps in endocytosis from the basolateral surface in polarized WIF-B cells.

102 high E-/P-cadherin cells, Na/K ATPase was on basolateral surfaces in addition to microvilli.

103 bacteria were added to either the apical or basolateral surfaces, indicating that the RTX toxin rece

104 cells and OVA(323-339) peptide placed on the basolateral surface (inverted) was 2- to 3-fold greater

105 /2 the apical surface is 15-30 min; t1/2 the basolateral surface is 8-10 h).

106 rsely, we find that protein secretion at the basolateral surface is focused on components of the extr

107 ons, the majority (>65%) of recycling to the basolateral surface is likely to occur from early endoso

108 t localized preferentially (over 99%) to the basolateral surface, like constitutive caveolae of MDCK

109 which was consistent with the apical and not basolateral surface localization of two essential viral

110 epithelial cells revealed a similar punctate basolateral surface localization.

111 binding and post-trans-Golgi trafficking to basolateral surface membranes but not for its turnover a

112 tion through inducing internalization of the basolateral surface NKCC1.

113 tracellularly from the apical surface to the basolateral surface occurred over time, and bacterial re

114 on of viral receptors and coreceptors to the basolateral surface of airway epithelial cells has been

115 an overwhelming preference for entry at the basolateral surface of airway epithelial cells, which le

116 hanger AE1 that is normally expressed at the basolateral surface of alpha-intercalated cells in the d

117 eveloped a method of applied pressure to the basolateral surface of alveolar epithelia.

118 s regulated by Na+/K+-ATPase activity on the basolateral surface of alveolar epithelial cells.

119 ing that it is vectorially secreted from the basolateral surface of ARPE-19 cells.

120 of the Let-23 growth factor receptor to the basolateral surface of body epithelia.

121 Imaging and analysis of the basolateral surface of cells expressing some 50 molecule

122 CXCL12 is expressed at the basolateral surface of CNS endothelial cells in normal s

123 When applied to the basolateral surface of colonocytes, PAR2 agonists and ma

124 us-mediated gene transfer from the apical or basolateral surface of confluent AEC monolayers (R(t) >

125 apical surface and aerobic conditions at the basolateral surface of cultured IECs, producing an in vi

126 Mammalian Ferroportin1 is expressed at the basolateral surface of duodenal enterocytes and could ex

127 at intestinal ZnT-1 was most abundant at the basolateral surface of enterocytes lining the villi of t

128 In the duodenum, FPN1 localizes to the basolateral surface of enterocytes where it appears to e

129 aps by mediating cholesterol efflux from the basolateral surface of enterocytes, it remains unclear w

130 endings of enteric neurons terminate at the basolateral surface of epithelial cells and do not conta

131 d by the polymeric Ig receptor (pIgR) on the basolateral surface of epithelial cells and transcytosed

132 ily infected lymphatic cells carry MV to the basolateral surface of epithelial cells, supporting MV s

133 t of many membrane proteins destined for the basolateral surface of epithelial cells.

134 of the Let-23 growth factor receptor to the basolateral surface of epithelial cells.

135 jejuni invasion occurs preferentially at the basolateral surface of eukaryotic cells.

136 ntrast, infected MDMs and DCs applied to the basolateral surface of HAE grown on large-pore (3.0-mum)

137 ikewise, infected MDMs or DCs applied to the basolateral surface of HAE grown on small-pore (0.4-mum)

138 d nectin-4 to efficiently deliver MeV to the basolateral surface of HAE.

139 anic anion transport proteins (OATPs) on the basolateral surface of hepatocytes mediate uptake of a n

140 ed that the NTCP protein is expressed on the basolateral surface of hepatocytes.

141 nd functional IL-17R signaling occurs on the basolateral surface of human bronchial epithelial (HBE)

142 or reduced expression of the protein on the basolateral surface of injured cells permits spontaneous

143 ed that TLR5 is expressed exclusively on the basolateral surface of intestinal epithelia, thus provid

144 ss of heparan sulfate proteoglycans from the basolateral surface of intestinal epithelial cells durin

145 ecific loss of heparan sulfate (HS) from the basolateral surface of intestinal epithelial cells only

146 ptor shown to be abundantly expressed on the basolateral surface of intestinal epithelium.

147 6 +/- 12.8 nM (n = 6) when positioned at the basolateral surface of isolated perfused MD cells and [N

148 istribution of many membrane proteins to the basolateral surface of LLC-PK1 kidney cells.

149 urrent study we found that DCs docked to the basolateral surface of lymphatic vessels and transited t

150 ry from the trans-Golgi network (TGN) to the basolateral surface of Madin-Darby canine kidney (MDCK)

151 ha and that TGF-alpha is not detected at the basolateral surface of Madin-Darby canine kidney (MDCK)

152 When Y8 was applied to the basolateral surface of Madin-Darby canine kidney cells e

153 3i loop tethering of the alpha(2A)-AR to the basolateral surface of Madin-Darby canine kidney cells.

154 HA+8 was also sorted efficiently to the basolateral surface of Madin-Darby canine kidney cells.

155 Addition of PtdIns(3,4,5)P3 to the basolateral surface of MDCK cells grown as cysts caused

156 sis than dyn1(K44A) in HeLa cells and at the basolateral surface of MDCK cells.

157 hich was secreted predominantly (80%) to the basolateral surface of MDCK cells.

158 that stabilization of the alpha2A-AR on the basolateral surface of MDCKII cells involves multiple me

159 hree alpha 2-AR subtypes, is enriched at the basolateral surface of MDCKII cells.

160 th forms of VacA bound preferentially to the basolateral surface of organoid monolayers and caused in

161 nic composition of the fluid surrounding the basolateral surface of outer hair cells.

162 vo, laminin is primarily concentrated at the basolateral surface of pneumocytes where they rest on th

163 abundantly expressed on the apical than the basolateral surface of polarized airway epithelia.

164 opose that translocation of ExoU through the basolateral surface of polarized airway epithelial cells

165 ng signal that directs Env expression to the basolateral surface of polarized cells.

166 These data demonstrate that the basolateral surface of polarized epithelia is more susce

167 alpha) and amphiregulin are delivered to the basolateral surface of polarized epithelial cells where

168 rtain virus receptors are sequestered on the basolateral surface of polarized epithelial cells.

169 gradation, thus ensuring its delivery to the basolateral surface of polarized epithelial cells.

170 taining vesicles to a distinct region at the basolateral surface of polarized epithelial cells.

171 release from the apical surface but not the basolateral surface of polarized hepatocytes.

172 ical for retention of these receptors at the basolateral surface of polarized Madin-Darby canine kidn

173 alpha2A AR) is critical for retention at the basolateral surface of polarized Madin-Darby canine kidn

174 etaine transporter (BGT) is expressed on the basolateral surface of polarized Madin-Darby canine kidn

175 lly, EREG is preferentially delivered to the basolateral surface of polarized Madin-Darby canine kidn

176 ly tether cargo vesicles directed toward the basolateral surface of polarized Madin-Darby canine kidn

177 and that spinophilin is enriched beneath the basolateral surface of polarized MDCK cells prompted us

178 een fluorescent protein--specifically to the basolateral surface of polarized MDCK cells.

179 e receptor that achieves localization on the basolateral surface of polarized MDCK II cells indisting

180 ergic receptor (alpha2A-AR) retention at the basolateral surface of polarized MDCKII cells involves i

181 ent regulation of alpha(2B)AR density at the basolateral surface of polarized MDCKII cells requires t

182 g and maintenance of the EGF receptor on the basolateral surface of renal epithelial cells is perturb

183 NSP4 colocalizes with integrin alpha2 on the basolateral surface of rotavirus-infected polarized inte

184 l microvilli, whereas SAP97 localizes at the basolateral surface of RPE cells, probably through a dir

185 -associated protein of 97 kDa (SAP97) at the basolateral surface of RPE cells, which overlapped with

186 g receptor (pIgR), which is expressed on the basolateral surface of secretory epithelial cells.

187 ecretory response when it was applied to the basolateral surface of T84 cells but no response when it

188 indicated that C. jejuni binds to Fn on the basolateral surface of T84 human colonic cells.

189 d Crry regulate complement activation on the basolateral surface of TECs and that factor H regulates

190 ater complement activation occurred when the basolateral surface of TECs from Crry(-/-)fB(-/-) mice w

191 complement activation was observed when the basolateral surface of TECs was exposed to serum than wh

192 confirmed expression of mBSC2 protein on the basolateral surface of terminal IMCD segments and demons

193 8 was highly polarized and restricted to the basolateral surface of the cell.

194 larization were localized to hotspots on the basolateral surface of the cell.

195 tes with biotinylated FGF2 revealed that the basolateral surface of the cells remained intact, withou

196 When the basolateral surface of the cells was treated with antibo

197 tends a tubular process, or canal, along the basolateral surface of the epidermis to form the nematod

198 ntigen 2 within the hemidesmosomes along the basolateral surface of the epithelial cell and their lig

199 During this process, dIgA binding at the basolateral surface of the epithelial cell transmits a s

200 nonmotile organisms that advanced toward the basolateral surface of the epithelium while adhering to

201 s engagement with receptors expressed on the basolateral surface of the epithelium.

202 istochemistry localized both subunits to the basolateral surface of the mouse ileal enterocyte.

203 ocalizes with complement deposited along the basolateral surface of the proximal renal tubule in asso

204 It is distributed specifically along the basolateral surface of the RPE and is proposed to work i

205 ient from acidic endosomes to the pH-neutral basolateral surface of the syncytiotrophoblast.

206 hways that direct proteins to the apical and basolateral surface of these cells.

207 tein that mediates active I(-) uptake in the basolateral surface of thyrocytes and other cells.

208 emokines were expressed predominantly at the basolateral surface of tubular epithelial cells.

209 When HCoV-229E was applied to the apical or basolateral surface of well-differentiated primary cultu

210 of E-cadherin at the adherens junctions and basolateral surfaces of 129/Sv (DeltaN89 beta-catenin) i

211 Basolateral surfaces of cells were exposed by one of two

212 nt-specific cargo released by the apical and basolateral surfaces of ECs can reprogram monocytes and

213 Immunohistochemistry localizes ZIP5 to the basolateral surfaces of enterocytes, acinar cells, and v

214 esults suggest that there are factors on the basolateral surfaces of epithelial cells that promote in

215 the protein was found on both the apical and basolateral surfaces of epithelial cells, as was gD.

216 otein E (gE) promotes cell-to-cell spread at basolateral surfaces of epithelial cells, but its activi

217 ted by immunofluorescence selectively at the basolateral surfaces of freshly excised human airway epi

218 dies have demonstrated that PMN contact with basolateral surfaces of intestinal epithelial cells in t

219 Exposure of the basolateral surfaces of MDCK cells to P. gingivalis (>10

220 trilysin co-localized with E-cadherin at the basolateral surfaces of migrating tracheal epithelium, a

221 in binding is also expressed in vivo on the basolateral surfaces of mucosal epithelium and lamina pr

222 ay preferentially occur at the apical or the basolateral surfaces of polarized cells, and differences

223 re found to be localized specifically at the basolateral surfaces of polarized Madin-Darby canine kid

224 ial adhesin, MrkD, mediates adherence to the basolateral surfaces of renal and pulmonary epithelia an

225 First, BFT applied to either the apical or basolateral surfaces of T84 monolayers diminished monola

226 creased significantly after PMN contact with basolateral surfaces of T84 monolayers or after incubati

227 enabled independent access to the apical and basolateral surfaces of the cholangiocyte channel, allow

228 is to form a barrier between the apical and basolateral surfaces of the epithelium.

229 mmunofluorescence was most intense along the basolateral surfaces of the PE cells.

230 ns in the context of the distinct apical and basolateral surfaces of the polarized epithelium that li

231 e of specific taurine carriers on apical and basolateral surfaces of the RPE.

232 The release of ATP from the apical and basolateral surfaces of the urothelium appears to be med

233 orrelated with CPE binding the apical versus basolateral surfaces of these two cell lines.

234 apical cell-cell junctions was reduced, and basolateral surfaces of those cells were separated by mu

235 naptic terminals (calyces) that envelope the basolateral surfaces of type I hair cells.

236 to integrin overexpressed on the abluminal (basolateral) surface of endothelial cells through vascul

237 ant L292P V2R escapes to the apical, but not basolateral, surface of polarized MDCK II cells, even in

238 tively released ATP from the apical, but not basolateral, surfaces of CF cells grown on permeable sup

239 polarized epithelia only when applied to the basolateral surface or when injury compromised tight jun

240 s FcRn-IgG complexes that transcytose to the basolateral surface pass through downstream Rab11-positi

241 Cl- removal from apical and basolateral surfaces produced cellular alkalinization (a

242 ively define large populations of apical and basolateral surface proteins in Madin-Darby canine kidne

243 [57Co]cobalamin (Cbl), to the apical and the basolateral surfaces, respectively.

244 ut led to a relocalization the A1AdoR to the basolateral surface, revealed by immunocytochemical and

245 to virus through the apical rather than the basolateral surface showed high levels of viral replicat

246 Binding of dIgA to pIgR at the basolateral surface stimulates subsequent transcytosis t

247 a was more efficient after adsorption to the basolateral surface than after adsorption to the apical

248 of 185-kD proEGF is fourfold greater at the basolateral surface than at the apical surface and is se

249 bility to distinguish between the apical and basolateral surfaces that are located at intercellular t

250 When applied to the basolateral surface, the anti-SC Fv/alpha(1)-AT fusion p

251 n to selectively deliver wild-type TR to the basolateral surface; this result is consistent with the

252 helial cells can define a subdomain on their basolateral surface through MT-based transport and highl

253 ) in Calu-3 cells exposed from the apical or basolateral surface to cytotoxic and noncytotoxic strain

254 Fluorescent albumin crossed the gland from basolateral surface to lumen via cytoplasmic vesicles, b

255 s pIgR molecules that have bound dIgA at the basolateral surface to respond to the signal of stimulat

256 as been postulated to export iron across the basolateral surface to the circulation.

257 te distinct signaling agendas via apical and basolateral surfaces to communicate with different cell

258 rmits exposure of the hair cell's apical and basolateral surfaces to different solutions, we examined

259 ls on porous filters that allowed apical and basolateral surfaces to form.

260 Infection from the apical but not the basolateral surface triggered focal adhesion kinase phos

261 n carcinoma cells detected hephaestin on the basolateral surface under steady-state conditions.

262 surface are selectively transcytosed to the basolateral surface underscoring the importance of basol

263 te HIV type 1 (HIV-1) from the apical to the basolateral surface via vesicular transcytosis.

264 Invasion via the basolateral surface was at least 2-log(10) units more ef

265 Complement activation on the apical and basolateral surfaces was also greater when factor H, an

266 Although delivery to the basolateral surfaces was direct and independent of any d

267 , that is involved in sorting of proteins to basolateral surfaces was involved in targeting of PRV pa

268 s are able to form adherens junctions at the basolateral surface, we show that they have specific and

269 ion and is capable of directing GAT-3 to the basolateral surface when appended to the C terminus of t

270 tor subtype 7a (mGluR7a) is polarized at the basolateral surface when expressed in Madin-Darby canine

271 Vesicles migrated to the basolateral surface where they released FM 1-43, the flu

272 In Xenopus, the blastocoel-facing, basolateral surfaces where signaling interactions ostens

273 eceptor (TR) is selectively delivered to the basolateral surface, where it internalizes transferrin v

274 ion of polarized cells was restricted to the basolateral surface whereas virus was released apically,

275 syntaxin 2 was found on both the apical and basolateral surface, whereas the plasma membrane localiz

276 , ARTL27 was preferentially cleaved from the basolateral surface with 4-fold greater efficiency compa

277 cal surface was more efficient than from the basolateral surface with shedding of viable MeV-producin

278 osomal elements directly accessible from the basolateral surface with transferrin (Tf)-HRP, we show t

279 m subsp. paratuberculosis crosses apical and basolateral surfaces with approximately the same degree

280 MDCKII cells: random delivery to apical and basolateral surfaces with rapid (t(1/2) < or = 60 min) a