ライフサイエンスコーパス: be cleared from

1 that by 12 months after treatment, dysplasia was cleared from 81%.

2 HGD was cleared from 86% of patients, all dysplasia from 81%

3 It is unclear how virus particles are cleared from afferent lymph and presented to cognate

4 treatment, we discovered that EBOV, despite being cleared from all other organs, persisted in the br

5 the amount decreased over time, and VNP20009 was cleared from all organs by day 41; no VNP20009 could

6 ection and disseminate to distal tissues but was cleared from all sites by 14 days postinfection.

7 urotransmitter release and suggest that Ca2+ is cleared from an active zone almost exclusively by mob

8 cells and autoreactive stalk antibodies that were cleared from B cell memory.

9 Our findings suggest that CCL2 is cleared from blood in a CCR2-dependent but G protein

10 Although viral RNA during primary infection was cleared from blood plasma and urine within 10 d, vir

11 Viruses were cleared from blood by day 7 and from tissues around

12 e measurement shows 86% of the gold clusters are cleared from body without any acute or long-term tox

13 CM is cleared from both the genital tract and small intesti

14 In young mice, Abeta-anti-Abeta complexes were cleared from brain to blood by transcytosis across

15 ized by MRI of gadolinium-labelled AuNPs and were cleared from brain within 24 h and excreted through

16 In immunocompetent mice, CHIKV is cleared from cardiac tissue without significant damag

17 iquitinated species, and that these products are cleared from cells following inhibition release.

18 er a period of several hours, each component being cleared from cells within 1 day.

19 However, the bulk of LPS can be cleared from circulation by the liver.

20 CPPs must be cleared from circulation to prevent local deposition

21 Red blood cells (RBCs) can be cleared from circulation when alterations in their si

22 an equivalent number of senescent cells must be cleared from circulation.

23 In vivo, pGCR and rGCR were cleared from circulation by a saturable pathway.

24 eased susceptibility to oxidative stress and was cleared from corneal tissue significantly better (P

25 In addition, within 24 h of delivery, > 90% were cleared from ear biopsies.

26 interferon (IFN) production or signaling but is cleared from IFN signaling-competent cells.

27 s suggest that superfluous endothelial cells are cleared from immature glomerular capillaries by apop

28 allenging the widely accepted axiom that RSV is cleared from immunocompetent hosts within weeks from

29 with wild-type Yersinia strain and begins to be cleared from infected spleens on day 4 after infectio

30 h granulocytes and their histotoxic contents are cleared from inflamed sites during resolution.

31 Consequently, they were cleared from interferon (IFN)-competent cells witho

32 HEV genotype 3 (gt3) infections were cleared from liver and feces within 8 pegIFNalpha d

33 report that misfolded cytosolic proteins can be cleared from mammalian cells by directing them to end

34 Tetracycline was found to be cleared from mice relatively fast in comparison with

35 Finally, we found that MPXV was cleared from most organs during convalescence, inclu

36 125I-labeled rh-FcgammaRIA was cleared from mouse blood with a rapid distribution p

37 The triple mutant was cleared from mouse organs rapidly, with concurrent d

38 ulated intranasally into mice, rM51R-M virus was cleared from nasal mucosa by day 2 postinfection and

39 ing the mechanisms by which metabolic wastes are cleared from nervous tissue is important for underst

40 in 7-8 days after infection infectious virus is cleared from neurons through the antiviral effects of

41 Lysosomal distention was cleared from neurons and glial cells in the vicinity

42 This enabled maternally deposited Piwi to be cleared from newly laid embryos within 30 min and wel

43 from the remainder of nucleus, and failed to be cleared from nucleoli in response to camptothecin tre

44 n the inoculum size and whether the bacteria are cleared from or proliferate in the lungs.

45 ted rhesus monkeys for weeks after virus has been cleared from peripheral blood, urine, and mucosal s

46 ated cattle, systemically disseminated virus was cleared from peripheral sites by 10 dpi, while virus

47 Small, dense LDL are cleared from plasma relatively slowly and tend to ac

48 Radioactivity was cleared from plasma at an average rate of 136 mL/h,

49 54173717 crossed the blood-brain barrier and was cleared from plasma mainly via the hepatobiliary pat

50 Consistently, exogenously infused virions were cleared from plasma with an extremely short half-li

51 that during slow-wave sleep (SWS), the brain is cleared from potentially toxic metabolites, such as t

52 ited budget requires some of the patients to be cleared from precaution (the clearance problem).

53 nganese accumulated in normal myocardium but was cleared from reperfused infarction and blood.

54 The virus is cleared from resistant mice with no resulting demyeli

55 Liquid Bev formulations were cleared from SCS within 5 days, even when formulate

56 e; in 95% of the men in this study, ZIKV RNA was cleared from semen after about 3 months.

57 GXM was cleared from serum with a half-life of 24-48 h but w

58 known about how mononuclear phagocytes (MP) are cleared from sites of inflammation as inflammatory l

59 Treponema pallidum is cleared from sites of infection by opsonization, inge

60 tion or the health of the animal, and Mn(2+) was cleared from skeletal muscle rapidly.

61 It is unclear why T. cruzi is cleared from some tissues but persists in others, des

62 Virus was cleared from spinal cord and brain stem neurons, but

63 ed that the anti-Id, unlike anti-MHCII, MoAb was cleared from target cells in vivo and delivered 4 ti

64 Apolipoprotein E2-containing VLDL particles were cleared from teh circulation more slowly and were m

65 so large (approximately 38,000 S) that they are cleared from the analytical ultracentrifuge even at

66 oites, lactoferrin, and remnant lipoproteins are cleared from the blood by similar mechanisms.

67 ence of RF borreliae in the brain after they are cleared from the blood, referred to as residual brai

68 e healthy tissue through the lymphatics, and are cleared from the blood.

69 rum multiply in red blood cells (RBC), which are cleared from the bloodstream by the spleen when thei

70 Foreign particles and cells are cleared from the body by phagocytes that must also r

71 humans that develop rapidly after the drugs are cleared from the body.

72 due to nonproductive Ig gene rearrangements are cleared from the bone marrow by macrophages.

73 through which cortical interstitial solutes are cleared from the brain, has recently been linked to

74 It is thought that protein aggregates are cleared from the bud via actin cable-based retrograd

75 rocess wherein misfolded or damaged proteins are cleared from the cell to maintain protein homeostasi

76 Atherogenic low density lipoproteins are cleared from the circulation by hepatic low density

77 immunoglobulin G (IgG)-opsonized blood cells are cleared from the circulation by macrophages.

78 und to other sites on E, in many cases the E are cleared from the circulation by the mononuclear phag

79 The rate at which glycoproteins are cleared from the circulation has a critical impact o

80 noglobulin G1 version of the antibody (B2G1) are cleared from the circulation in 2 hours.

81 er (RRV), and o'nyong 'nyong (ONNV) viruses, are cleared from the circulation of mice by liver Kupffe

82 ls, we show that in mice, 32% of neutrophils are cleared from the circulation via the bone marrow.

83 gh it is generally believed that neutrophils are cleared from the circulation via the liver and splee

84 e, we report that IgM hexamers and pentamers are cleared from the circulation with similar kinetics,

85 membrane C3 regulator-deficient erythrocytes are cleared from the circulation.

86 Ultimately, attenuated RABV are cleared from the CNS tissues of WT mice by Ab locall

87 ds, whereas the rate that active macrophages are cleared from the dermis is the principle determinant

88 We have determined that nurse cells are cleared from the Drosophila egg chamber by apoptosis

89 To ensure that aberrantly folded proteins are cleared from the endoplasmic reticulum (ER), all euk

90 idarum-C57 mouse model, chlamydial organisms are cleared from the genital tract in ~4 weeks, but the

91 most RNA viruses cause acute infections that are cleared from the host as they lack the mechanisms to

92 can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical

93 nds of receptor activation, calcium channels are cleared from the membrane and sequestered in clathri

94 question of how larger cytoplasmic molecules are cleared from the nucleus.

95 entially other ganglioside binding proteins, are cleared from the systemic circulation and also cover

96 ptotic cells in real time as they emerge and are cleared from the zebrafish brain.

97 escence and long-term toxicity, they need to be cleared from the body within a reasonable timescale.

98 n, after protein release, the polymer has to be cleared from the body, a significant design challenge

99 glial cells is one means by which Abeta may be cleared from the brain.

100 CtrA cell cycle master regulator, that must be cleared from the Caulobacter cell to allow the initia

101 Damaged mitochondria can be cleared from the cell by mitophagy, using a pathway f

102 STATEMENT All synaptic transmitters need to be cleared from the extracellular space after release, a

103 The results indicate that glutamate can be cleared from the extrasynaptic space within 1 ms.

104 This complex may then be cleared from the interstitial space by apoE receptors

105 ng catheters, all crystalloid solutions must be cleared from the line.

106 cking the conserved pigmentation locus could be cleared from the lungs in the absence of Cxcr2 indica

107 position of HIV-1, and much of the virus can be cleared from the network with antiretroviral therapy,

108 to polyglutamine aggregates causes TDP-43 to be cleared from the nucleus and become detergent-insolub

109 with the fact that apo-B100-lipoproteins can be cleared from the plasma via the LDL receptor, whereas

110 In addition, the chromosome must be cleared from the region of formation of the division

111 s of canola seed development when Chl should be cleared from the seed.

112 lood at 24 h while >99% of injected AAV2 has been cleared from the blood by 1 h.

113 er neutralizing antibodies appear, virus has been cleared from the blood, and fecal virus shedding ha

114 t prevents abscission until chromosomes have been cleared from the cytokinetic machinery.

115 been retained, whereas approximately 70% had been cleared from the liver and kidney.

116 In addition to being cleared from the circulation by urinary excretion,

117 RG2TK+ xenografts, whereas FHBG and FHPG are being cleared from the HSV1-tk transduced and wild-type

118 ding off-target accumulation in the lung and being cleared from the liver, resulted in rapid accumula

119 , but later retract so that their expression is cleared from the anterior-most segmented regions.

120 events effective penetration before the drug is cleared from the blood and a high diffusivity limits

121 nce Siaalpha2,6GalNAcbeta1,4GlcNAcbeta1,2Man is cleared from the blood of the rat with a half-life of

122 These studies demonstrate that CPS is cleared from the blood within days but is retained in

123 liver injury even after the hepatotoxic drug is cleared from the body.

124 e demonstrate in mice that extracellular tau is cleared from the brain along these paravascular pathw

125 al vessels play a major role in AD, as Abeta is cleared from the brain by pathways involving the cere

126 quently, identifying pathways by which Abeta is cleared from the brain is crucial for better understa

127 How excess fluid is cleared from the brain is not well understood.

128 n response to an inflammatory stimulus, EMCN is cleared from the cell surface by an unknown mechanism

129 ported here show that TRAIL receptor 2 (TR2) is cleared from the cell surface in Ad-infected cells.

130 While the virus is cleared from the central nervous system (CNS) of resi

131 eta2-microglobulin/ Nb24 pre-formed complex, is cleared from the circulation at the same rate as the

132 In addition, how uric acid is cleared from the circulation is incompletely understo

133 aches a peak concentration of 2.2-3.5 mM and is cleared from the cleft with a time constant of 0.6-0.

134 SKN-1A/Nrf1 is cleared from the ER by the ER-associated degradation

135 that remaining or misaddressed Pax6 protein is cleared from the eyestalk region to properly set the

136 ytic choriomeningitis virus (LCMV) infection is cleared from the hepatocyte noncytopathically when th

137 point that delays abscission until chromatin is cleared from the intercellular bridge.

138 Tc-99m MAG3 is cleared from the kidney by tubular secretion, whereas

139 ps B cell support of T cells; however, virus is cleared from the liver without the involvement of Abs

140 ar space enters the arterial wall and how it is cleared from the local environment.

141 ores the mechanism by which B. parapertussis is cleared from the lower respiratory tract by anamnesti

142 t secretion to net absorption as lung liquid is cleared from the lung at birth.

143 f oral ectoderm genes until their expression is cleared from the oral ectoderm as an indirect consequ

144 athways by which adventitially released drug is cleared from the perivascular space and those by whic

145 or excitatory neurotransmitter in the brain, is cleared from the synapse by glutamate transporters (G

146 r acts locally on postsynaptic receptors and is cleared from the synaptic cleft within a few millisec

147 se-dependent manner and (2) as dexamethasone is cleared from the system, a stable coexistence equilib

148 rain, will normally disappear once the virus is cleared from the system, but a severe respiratory vir

149 ourse of immunosuppression, until AAV capsid is cleared from the transduced cells, may mitigate the h

150 50% of monomeric scFv (approximately 27 kDa) was cleared from the blood in less than 10 min.

151 e point of peak AME(359) expression, cocaine was cleared from the blood too rapidly for accurate meas

152 nt strain but not the PspA-expressing strain was cleared from the blood within 6 h.

153 SS1P uptake peaked several hours after SS1P was cleared from the blood, reflecting an intratumor dis

154 lue to circulate in the vasculature, the dye was cleared from the bloodstream with saline, citrate, o

155 ravenous injection, 90% of the radioactivity was cleared from the brain.

156 ells correlated with the time at which virus was cleared from the central nervous system in both pare

157 ar to SA-21; in contrast, apelin-17 analogue was cleared from the circulation after 2 min.

158 we discovered that the ADAMTS13-cleaved VWF was cleared from the circulation by a Clec4f+Marcohigh m

159 all-plaque Toto 1101 strain of Sindbis virus was cleared from the circulation by the liver within min

160 hat the major portion of each IC preparation was cleared from the circulation by the liver.

161 Intravenously administered r-halphaGalA was cleared from the circulation in a dose-dependent man

162 intravenous administration, wild-type CXCL12 was cleared from the circulation rapidly, while the muta

163 damage; approximately 90% of mIgG/(125)I-tPA was cleared from the circulation within 30 minutes in bo

164 However, while virus was cleared from the CNS of wild-type mice, virus persis

165 ate at which intraparenchymally injected dye was cleared from the cortex to the PVS.

166 n rats studied 84-107 d postinfection, virus was cleared from the dentate gyrus and the number of den

167 activation, PAR-2, like thrombin receptors, was cleared from the endothelial cell surface and then r

168 ant gammaD domain in yeast and found that it was cleared from the ER via ERAD.

169 After vaccination, rLM was cleared from the host within 7 days while inducing a

170 titutively filamentous BCa2-10 (0%); BCa2-10 was cleared from the kidney and liver, but CAF2 and HLC5

171 Infectious virus peaked and was cleared from the livers of muMT and wild-type mice.

172 nable to overcome innate immune defenses and was cleared from the lower respiratory tracts of mice mo

173 In contrast, the unconjugated rhDNase was cleared from the lung lumina within 24 h and was onl

174 ly 25 % of instilled (125)I-labelled albumin was cleared from the lung preparations per hour by the d

175 Infection spread to the brain as it was cleared from the lung, again without leukocyte accum

176 at barium [from BaSO(4) nanoparticles (NPs)] was cleared from the lungs faster than other poorly solu

177 point seven percent of the MGAS2221 inoculum was cleared from the lungs of C57BL/6J mice at 24 h afte

178 adults during the acute phase but the virus was cleared from the lungs of neonates as efficiently as

179 thy, and it was the only group in which POWV was cleared from the lymph nodes.

180 LDL from STZ-induced diabetic mice was cleared from the plasma and trapped more rapidly by

181 sustained immune activation after the virus was cleared from the plasma, observed most strikingly in

182 The virus was cleared from the respiratory tract, and potent cytot

183 EHEC was cleared from the rumen within days and from the RAJ

184 arrow with minimal toxicity and the antibody was cleared from the serum before the neonatal transplan

185 The triple-mutant strain was cleared from the skin injection site significantly f

186 Sr2+ was cleared from the synaptic terminal with the same tim

187 eightfold around the time that trypanosomes were cleared from the blood, accompanied by a fivefold d

188 12 d, and 45% of generated (213)Bi daughters were cleared from the blood.

189 candidemia, comparing them to isolates that were cleared from the bloodstream early in the infection

190 lts indicated that agar-grown Reynolds cells were cleared from the bloodstream of mice less readily t

191 tinoculation; however, viruses G3N4 and G1N4 were cleared from the brain by 7 days postinoculation an

192 Hemolytic anemia recurred when drug levels were cleared from the circulation 3 to 4 weeks after the

193 ITC-D reached higher peak concentrations and were cleared from the eye more rapidly than was 70-kDa F

194 AMP-sensitive mutants were cleared from the gut after infection and aging-indu

195 Furthermore, qPCR detected predators were cleared from the host quickly and efficiently.

196 toxins were deleted, the colonizing bacteria were cleared from the intestine, and this clearance is d

197 4h indicating that small amounts of activity were cleared from the lungs both by translocation across

198 lethal doses of H10407 and B7A, the bacteria were cleared from the lungs of the mice at a steady rate

199 ponse, the P. carinii f. sp. muris organisms were cleared from the lungs.

200 The L2-17 organisms were cleared from the mouse lower genital tract within a

201 Both strains of virus were cleared from the perforin (-/-) mice as in the cont

202 ains lacking toxin-coregulated pili (TCP(-)) were cleared from the small bowel; however, an El Tor TC

203 at the gastrointestinal chlamydial organisms were cleared from the small intestine by day 28, paralle

204 ice was attenuated, and most of the bacteria were cleared from the spleen within 8 weeks.

205 er transfer, whereas long-term expanded CTLs were cleared from the system after 2 weeks.

206 ated strain of Listeria monocytogenes, which was cleared from these mice.

207 osis is the process by which apoptotic cells are cleared from tissue by phagocytic cells.

208 In this study, the possibility that MP could be cleared from tissues by migrating across endothelium

209 icacy testing; it produced immune responses, was cleared from visceral tissues, and produced less sev

210 EBV was cleared from whole blood by a first-order process wi