ライフサイエンスコーパス: be damaged

1 l as other disorders in which endothelia may be damaged.

2 e structures that are crucial for vision can be damaged.

3 narios it is likely that these systems would be damaged.

4 cause a G(2) cell cycle arrest when cell DNA is damaged.

5 tuations in which the endothelial glycocalyx is damaged.

6 ntegrity of the synthetic magnesium silicate is damaged.

7 real time, which occurs when muscular tissue is damaged.

8 ake errors, especially when the template DNA is damaged.

9 aling pathways in conditions where the liver is damaged.

10 oximately 10% of the oligonucleotide strands are damaged.

11 rate NHEJ when the terminal bases of the DSB are damaged.

12 undergoes regeneration only when hair cells are damaged.

13 he DNA repair machinery because both strands are damaged.

14 to develop interventions in cases where they are damaged.

15 uage in other cortical regions when LH areas are damaged.

16 d MGPCs when different retinal cell subtypes are damaged.

17 and to suppress lead leakage if the devices are damaged.

18 o occur, while CVH occur when cortical areas are damaged.

19 ipating their energy before proteins and DNA are damaged.

20 fferents are activated when outer hair cells are damaged.

21 overy after various injuries, in which AEC I are damaged.

22 arB, but the consequences of the interaction are damaged.

23 motor function when primary cortical regions are damaged.

24 s were detected where the epithelial surface was damaged.

25 and its SWV peaks at 0.04 V decreased as DNA was damaged.

26 super-oxide at pH 6.5, cytosolic fumarase B was damaged.

27 ted DNA from nematodes exposed to the nickel was damaged.

28 sharing the same milieu with cells that have been damaged.

29 helial tissue whose resident stem cells have been damaged.

30 in the remaining cells because the sites had been damaged.

31 long-term viability, since mitochondria had been damaged.

32 even after as long as 60 h after the DNA has been damaged.

33 , but the choroid, tapetum, and outer retina were damaged.

34 were used to detect which retinal cell types were damaged.

35 cal integrity and additional functions after being damaged.

36 When the skin is damaged, a variety of cell types must migrate, prolif

37 e 173,259 km(2) of marshes in the study area were damaged-a failure rate much lower than that of arti

38 Radial artery wall might be damaged after cannulation for cardiac catheterization

39 leus was also observed in murine livers that were damaged after chronic-plus-single binge or moderate

40 ce treated with SS1P, proximal tubular cells are damaged and albumin in the urine is increased.

41 Keratinocytes are damaged and briefly in contact with the parasites du

42 hich pancreatic insulin-producing beta cells are damaged and destroyed.

43 When cells are damaged and p21 is induced, DNA nucleotide excision

44 We also find that deficits are damaged and repaired over a wide range of timescales

45 cond laser fluences just before the nanorods are damaged and the remaining 10% plasmonic enhancement

46 n publicly-managed lands were less likely to be damaged and more likely to recover quickly from storm

47 y, a subset of supposedly "normal" mRNAs may be damaged and targeted by ZNF598, underscoring the impo

48 role in signaling that the DNA in a cell has been damaged and needs to be repaired.

49 Genomic DNA is constantly being damaged and repaired and our genomes exist at lesi

50 igm, coagulation is initiated after a vessel is damaged and blood is exposed to vessel-wall TF.

51 In mild asthma, the epithelium is damaged and fails to proliferate and to repair, where

52 During its normal function, PSII is damaged and frequently turned over.

53 Whether the stromal ME is damaged and how it recovers after irradiation is unkn

54 although cells adapt to high NaCl, their DNA is damaged and its repair is inhibited.

55 rkers of keratinocytes when the skin barrier is damaged and the extracellular calcium level is varied

56 of eukaryote chromosomes slows down when DNA is damaged and the proteins that work at the fork (the r

57 Both nuclear and cytoplasmic proteins were damaged and underwent K48-polyubiquitination.

58 uss how several key hair cell structures can be damaged, and what is known about how they are repaire

59 ion (allo-HSCT), the gastrointestinal mucosa is damaged, and colonizing bacteria are impacted, leadin

60 logic conditions, the endothelial glycocalyx is damaged, and its degradation is accompanied by sheddi

61 lon in experimental colitis where the mucosa is damaged, and this is likely to contribute to altered

62 takes place almost immediately after the DNA is damaged (approximately 2 min post-UV irradiation), wh

63 Polymers that can easily be repaired after being damaged are attractive as this characteristic can

64 roximately 1 helical turn, 10 bp) of the DNA is damaged, are lesions of enhanced biological significa

65 When biomaterials are damaged as a result of aging or stress, tissues unde

66 e the movement of limbs in which nerves have been damaged as a consequence of injuries affecting the

67 Organisms were damaged as shown by loss of cell wall integrity in

68 When the ventral route is damaged, as in the case of neurodegeneration affectin

69 support the view that in glaucoma RGC axons are damaged at the optic nerve head and degenerate withi

70 Either way, all organelles can be damaged at times, leading their contents to leak out

71 gy density per unit area) and are subject to being damaged at adequately high power (some antennas ca

72 However, if the lens is damaged at the time of nerve injury, many RGCs surviv

73 e nucleus at 1 and 2 days, and these neurons were damaged at 3 and 7 days.

74 otection cannot improve function if the axon is damaged, because the soma is still disconnected from

75 More than 50% of ganglion cells may be damaged before visual field loss is measurable by con

76 The penumbra is an area of brain tissue that is damaged but not yet dead after focal ischemia.

77 -zone cells die when their antigen receptors are damaged by activation-induced cytidine deaminase.

78 ) amyloidosis (AL) is a disease where organs are damaged by an overload of a misfolded patient-specif

79 Mitochondria are damaged by cisplatin, leading to reduced activity, b

80 erged that suggest MSC viability and potency are damaged by cryopreservation.

81 collapse ensues when these specialized cells are damaged by disease, a situation that currently neces

82 Hepatocytes are damaged by ethanol, via generation of reactive oxyge

83 genous nucleic acids, for example when cells are damaged by genotoxic agents and in certain autoinfla

84 White matter tracts are damaged by high shear forces during impact, resultin

85 Cortical regions that are damaged by insults, such as ischemia, hypoxia, and t

86 Hair cells of the inner ear are damaged by intense noise, aging, and aminoglycoside

87 ral ganglion neurons (SGNs) in the inner ear are damaged by noise trauma and with aging, causing "syn

88 f their hearts and that their cardiomyocytes are damaged by oxidative stress.

89 Many porous materials are damaged by pressure exerted by salt crystals growing

90 is not yet established whether HDL proteins are damaged by reactive nitrogen species in the circulat

91 in GCs might rescue B cells whose receptors are damaged by somatic mutations.

92 Here we have re-examined the cells that are damaged by these viruses, using lineage-specific mar

93 rated when a cell membrane or its components are damaged by various factors.

94 However, it's unclear how many cells would be damaged by a particular bursting bubble, or more prec

95 ntial to present antigen to T cells and thus be damaged by direct antigen-specific interactions with

96 Telomeres can be damaged by ionizing radiation and oxidative stress, a

97 neration, the retinal pigment epithelium can be damaged by light acting on photosensitizers like N-re

98 Bacterial DNA can be damaged by reactive nitrogen and oxygen intermediates

99 Cellular DNA can be damaged by spontaneous hydrolysis, reactive oxygen sp

100 Cooperative behaviours can be damaged by the emergence of 'cheating' cells that ben

101 d-feeding ticks must control C activation or be damaged by the host inflammatory response.

102 s one of the cellular constitutents that can be damaged by the interaction of A2E and blue light.

103 Alternatively, they might be damaged by the physiological stress of their efforts

104 ayer is challenging as this coating tends to be damaged by the repeated use of iodine and water, whic

105 pace of albino rats whose photoreceptors had been damaged by continuous exposure to blue light for 3

106 s DNA glycosylase for bases in DNA that have been damaged by free radicals.

107 how that splenocytes from lpr mice that have been damaged by gamma-irradiation expressed Fas protein.

108 tion but was downregulated in axons that had been damaged by glaucomatous injury and exhibited aberra

109 enes represent open reading frames that have been damaged by mutations, rendering the gene product no

110 the repair of iron-sulfur clusters that have been damaged by nitrosative stress, releasing nitric oxi

111 f the children were living in homes that had been damaged by rain, flooding, or both.

112 ian cells, the repair of DNA bases that have been damaged by reactive oxygen species is primarily ini

113 beling) to determine whether tumor cells had been damaged by ultrasound exposure.

114 ree postreplicational repair of DNA that has been damaged by ultraviolet irradiation.

115 blue light-dependent repair of DNA that has been damaged by ultraviolet light.

116 lly cueing in to the odor profile of a plant being damaged by a parasitized herbivore that contains t

117 stallization, thus preventing organisms from being damaged by freezing.

118 When the template DNA is damaged by a carcinogen, the fidelity of DNA replicat

119 for duplex DNA that contains uracil or that is damaged by a variety of agents.

120 velopment can be arrested if the tooth organ is damaged by either trauma or caries.

121 Epidermal structure is damaged by exposure to UV light, but the molecular me

122 hydroxyurea (HU) or aphidicolin or when DNA is damaged by gamma IR.

123 steps in the synthesis of secreted proteins is damaged by heat shock, resulting in a selective halt

124 The peripheral T cell pool is damaged by HIV-1 infection and can be regenerated by

125 Chk1 is required to prevent mitosis when DNA is damaged by ionizing radiation (IR), whereas either ki

126 es acting on DNA during ES indicate that DNA is damaged by mechanical forces, and the damage takes pl

127 Cellular DNA is damaged by nitric oxide (NO), a multifunctional biore

128 oughout the plant and beyond the tissue that is damaged by pests.

129 the case that the corticospinal tract (CST) is damaged by stroke, brings about such abnormal synergi

130 his observation confirms that retinal tissue is damaged by the development of a myopic crescent, rath

131 he basis of our data, the top graphene layer is damaged by the sputtering process, and the acid treat

132 oad area laser diode (LD) cavity when the LD was damaged by applying a high current.

133 riated urethral sphincter of older male rats was damaged by electrocoagulation.

134 Mice epidermal barrier was damaged by epicutaneous application of proteases and

135 n addition, DNA in buffered aqueous solution was damaged by ionizing radiation at different radiation

136 either in vitro or in GBM xenografts in mice was damaged by irradiation or treatment with etoposide,

137 ir signaling profile, every target cell that was damaged by perforin died by apoptosis.

138 generated to visualize how the cell membrane was damaged by phage lysis, antibiotics attack, or dehyd

139 , well-differentiated colon carcinoma cells, were damaged by aspiration and the ensuing response was

140 Leaves of mutants were damaged by exogenous oxalate and more susceptible t

141 ion mass spectrometry and DNA samples, which were damaged by gamma-irradiation or by H(2)O(2)/Fe(III)

142 Chambered stomachs were damaged by hypertonic saline followed by either aci

143 ly, we used three Arabidopsis genotypes that were damaged by mechanical wounding or by insects of var

144 When purified enzymes were damaged by O(2)(-) in vitro, activity could be comp

145 eted of Mirk became less viable because they were damaged by ROS, and had increased levels of G(1) cy

146 Older (manufactured before 2000) ICDs were damaged by the MR scans.

147 We hypothesised that only specific nuclei are damaged, by attacks affecting structures from which

148 block cell cycle progression when their DNA is damaged, cells still undergo frequent genetic rearran

149 nd its signal strength, the cell whose mtDNA was damaged could be screened by flow cytometry and its

150 Worms might be damaged directly by effector cells and molecules of t

151 snout or the sensory nerves innervating them are damaged during a critical period in development, whi

152 ximal tubules are rich in peroxisomes, which are damaged during AKI.

153 the biliary epithelium when large bile ducts are damaged during cholestasis or by toxins.

154 These chlorophyll binding proteins are damaged during photochemistry, especially under high

155 It is these cells which are damaged during progressive HIV-1 infection of the ce

156 To discover whether islet sympathetic nerves are damaged during the autoimmune destruction of islet B

157 In particular, protein molecules are damaged during X-ray diffraction experiments with pr

158 Eyes of patients with glaucoma may be damaged during sleep.

159 for myocardial ischemia and sudden death or be damaged during surgical intervention.

160 ripheral branch of the trigeminal nerve, can be damaged during the surgical removal of lower third mo

161 and may be one of the key ways in which DNA is damaged during aging.

162 ting to preserve the cartilage matrix, which is damaged during alphavirus infection.

163 These results suggest that if complex III is damaged during ischemia, PTP opening may result in su

164 dent regulation of DNase I activity when DNA is damaged during ischemic injury.

165 cur if the inferior alveolar or mental nerve is damaged during preparation of an osteotomy.

166 on, possibly because the cell body of origin was damaged during the injection procedure.

167 As with other macromolecules, lipids can be damaged (e.g., oxidized), and cells require quality c

168 response properties of striate neurons that were damaged (e.g., high spatial-frequency tuning, low c

169 ndrites stratifying in the OFF sublamina may be damaged early.

170 ssential for spatial and episodic memory but is damaged early in Alzheimer's disease and is very sens

171 It is shown that the ice can be damaged even before the cylinder arrives at the posit

172 ural environments, where bacterial walls can be damaged extensively or removed altogether.

173 ch is responsible for attention and arousal, is damaged first by Alzheimer's disease (AD) pathology.

174 e clusters, suggesting that the fault medium is damaged, foliated, and enriched with fluid.

175 studies indicate that the bone marrow stroma is damaged following bone marrow transplantation.

176 s observed when primary auditory cortex (A1) is damaged have led to the widespread view that A1 may h

177 oped rosettes if host pigment epithelium had been damaged, if trauma to the donor tissue occurred dur

178 to understanding mechanisms by which tissues are damaged, illuminating mechanisms of repair and regen

179 When ribosomes are damaged in a cell, i.e. during stressful conditions,

180 a proximate mechanism by which tubule cells are damaged in FSGS was tested.

181 and protect the retinal ganglion cells that are damaged in glaucoma are also in development.

182 es are necessary to determine if OPL and ONL are damaged in late disease due to retrograde trans-syna

183 Photoreceptors are damaged in many common eye diseases, such as macular

184 stem was examined to determine if Hcrt cells are damaged in PD.

185 ing functionally related areas of the brain, are damaged in PSP, leading to specific clinical deficit

186 Although oligodendrocytes and axons are damaged in these diseases, the roles T cells play in

187 igment epithelium (RPE), the two layers that are damaged in this blinding disease.

188 Peripheral nerves are damaged in various conditions, including through tra

189 The anterior visual pathways may also be damaged in a retrograde, transsynaptic fashion in cas

190 The corticospinal tract was most likely to be damaged in both subgroups.

191 However, such nano-structures can be damaged in high power applications such as heat resis

192 of ecological systems around the world have been damaged in recent years, either by natural factors

193 In ischaemia myelin is damaged in a Ca(2+)-dependent manner, abolishing acti

194 nuclear and mitochondrial DNA as well as RNA is damaged in AD.

195 teraction is disrupted when the frontal lobe is damaged in disease, and in extreme cases patients are

196 It is damaged in diseases associated with elevated levels o

197 a mouse model in which the mitochondrial DNA is damaged in dopaminergic neurons.

198 As such, the endothelium is damaged in many pathologies, characterized by dysregu

199 The structural integrity of tissue proteins is damaged in processes ranging from remodeling of the e

200 hat the ubiquinol oxidation site at center P is damaged in the bc(1) complexes with Rieske proteins l

201 lls (AEC I) when the normal AEC I population is damaged in the lung alveoli.

202 ECM is damaged in the process of isolating human islets for

203 DNA is damaged in vivo by the Fenton reaction mediated by Fe

204 This same area was damaged in a patient with pure alexia ("alexia witho

205 No single brain region was damaged in all cases.

206 Although the STG was damaged in half of our MCA neglect patients, it was

207 As in yeast, lipoic acid cofactor was damaged in human D444V-homozygous fibroblasts after

208 This cluster-containing enzyme was damaged in vitro by molecular oxygen but not by supe

209 At 40 degrees C the organisms are damaged: in this case biocides at concentrations 10x

210 ulances and vehicles and 7 health facilities were damaged, including one hospital and three medical f

211 eliminates soluble cytoplasmic proteins that are damaged, incorrectly folded, or targeted for selecti

212 al representations and computations that can be damaged independently of each other.

213 lusions that (i) renewal mechanisms have not been damaged irreparably even at relatively advanced sta

214 How nematodes are damaged is unclear.

215 When the robot is damaged, it uses this prior knowledge to guide a tria

216 to ensure that when a sensory cortical area is damaged, its basic sensory functions are 'taken over'

217 When skin barrier is damaged, keratinocyte differentiation is triggered, a

218 Many of these tablets are damaged, leading to missing information.

219 ll tumour tissue, but normal tissue can also be damaged, leading to toxicity.

220 In sepsis, this emergency myelopoiesis is damaged, leading to failure of bacterial clearance, a

221 e mechanisms by which retinal ganglion cells are damaged may provide information required to develop

222 icate that regardless of which nuclear layer was damaged, MG respond by generating multipotent progen

223 ructure accounting for punctate labeling may be damaged mitochondria, lipofuscin or amyloid deposits.

224 liomyelitis-like disease where motor neurons are damaged, MUNE may also be a sensitive clinical or th

225 l to the CCFM of binge rats indicated myelin was damaged on axons in the mPFC.

226 cal production are disrupted when hair cells are damaged or lost but that these behaviors return to n

227 for ammonia assimilation, when mitochondria are damaged or non-functional because of glucose ferment

228 yond simple ligation when the terminal bases are damaged or not fully compatible.

229 When nerves are damaged or not working properly, using exogenous ele

230 on when hepatocytes and bile duct epithelium are damaged or unable to proliferate.

231 the ClpP peptidase to degrade proteins that are damaged or unneeded.

232 ow-timescale disturbances occur when muscles are damaged or when limb dynamics change as a result of

233 in both types of disease, and helminths can be damaged or killed by toxic products released by eosin

234 Neurons in the brain can be damaged or lost from neurodegenerative disease, strok

235 ly useful in generating cell types that have been damaged or depleted by a variety of human diseases.

236 stributes to the outer leaflet when the cell is damaged or at the onset of apoptosis.

237 , and electrical pathways by which the heart is damaged or dies.

238 rin expression is altered when the epidermis is damaged or diseased, and there is good evidence that

239 When DNA is damaged or DNA replication goes awry, cells activate

240 s and suggest that when the occipital cortex is damaged or inhibited, and the visual processing for e

241 re characteristic of whether the target base is damaged or is a normal base within a mispair.

242 ransduction pathways prevents mitosis if DNA is damaged or its synthesis incomplete.

243 DNA replication when either the template DNA is damaged or the replication machinery malfunctions.

244 inases (Cdks) to arrest cell cycles when DNA is damaged or unreplicated.

245 Checkpoint mechanisms delay mitosis when DNA is damaged or upon replication stress, but little is kno

246 genes cause arrest of cell division when DNA is damaged or when DNA replication is blocked.

247 th the checkpoint arrest of mitosis when DNA is damaged or when mitotic spindles have formed aberrant

248 orporation was the same whether the template was damaged or nondamaged.

249 elop a second embryo when the initial embryo is damaged, or when response to the signaling molecule a

250 In normal cells in which DNA has been damaged, p53 induces the expression of p21(Waf1/Cip

251 When this area is damaged, patients become more utilitarian (the ends j

252 astrointestinal tract, and peripheral nerves are damaged; Pompe's disease, in which the heart, skelet

253 analysis showed between 30 and 60% of voxels were damaged post-RT.

254 cted to gentle purification procedures, they were damaged, preventing generation of reliable structur

255 Proteins and other macromolecules are damaged primarily by ionizing X-ray photons and seco

256 However, the grafts are damaged, probably at many stages before, during and

257 The invaded cells are damaged, protrude towards the midgut lumen and suffe

258 drocytes, the myelinating processes of which are damaged rapidly in low energy conditions.

259 When a neuronal system is damaged, recovery may occur by engaging residual (e.g

260 in an individual, the same retinal location is damaged, regardless of visual function under test; gl

261 endothelial lining of cerebral microvessels is damaged relatively early after cerebral ischemia/repe

262 ally, under inflammatory conditions, the eGC is damaged, resulting in enhanced vascular permeability,

263 containing at least one copy of the Bax gene were damaged severely by exposure to excitotoxins or by

264 Additionally, 5'-AT-3' sites, which are damaged significantly more in the hybrid than in DNA

265 TP opening can be sustained when complex III is damaged (simulated by antimycin).

266 When the DNA molecule is damaged (specifically, a gap was created by removing

267 d that the tissue environment in which axons are damaged stimulates distinct regenerative mechanisms.

268 anoparticles rolls across a surface that has been damaged, stopping to repair any defects it encounte

269 ging situations, or when the auditory system is damaged, strains cortical resources, and this may cha

270 ior, but not the anterior, region of the RSC is damaged, suggesting that the role of the RSC in memor

271 However, after DNA is damaged, the activated p53 executes rapid apoptosis i

272 ct their phenotype; however, when the retina is damaged, the Ascl1-expressing glia initiate a respons

273 When DNA is damaged, the DNA damage response (DDR) can be initiat

274 When the human primary visual cortex (V1) is damaged, the dominant geniculo-striate pathway can no

275 Mitochondrial DNA (mtDNA) is damaged, the transcription of mtDNA-encoded genes is

276 When V1 was damaged, the typical V5/MT+ response to increasing c

277 axons of short thoracic propriospinal cells are damaged, their cell bodies of origin remain intact 2

278 If the midgut epithelium is damaged, then ISC proliferation increases [6-12].

279 ' to find a compensatory behaviour when they are damaged: they are limited to their pre-specified sel

280 that we like or feel that our relationships are damaged through the intervention of third parties.

281 of AT residues is essential and the A sites are damaged to a greater extent than they are in DNA.

282 icits, but the specific neural circuits that are damaged to drive changes in memory remain unknown.

283 correlated with the number of sites that may be damaged to form a single membrane defect.

284 , over the centuries, many inscriptions have been damaged to the point of illegibility, transported f

285 was dramatically decreased when plasmid DNA was damaged to contain multiple types of DNA adducts, al

286 When DNA was damaged using ultraviolet (UV) radiation (lambda=254

287 available, if the retinal pigment epithelium is damaged, we have to cope with the impossibility of re

288 cs, which are based on multi-layer coatings, are damaged when illuminated by high-power CW laser ligh

289 Higher percentage of cells is damaged when the size of electrodes is smaller.

290 cal tubules (90%), and most cortical tubules were damaged, whereas few glomerular cells expressed MCP

291 Myelin is damaged with normal ageing and in several neurodegene

292 line-treated laminin-alpha2-deficient muscle was damaged with cardiotoxin and muscle regeneration qua

293 Our data suggest that the glycocalyx is damaged within human liver grafts during preservation

294 DNA, contrasted with the multiple sites that were damaged within the observed segment of the collagen