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1 rsening sinus symptoms, and infrequent AECRS was defined as 0 to 3 episodes.
2                            Treatment failure was defined as (1) any further surgical procedure relate
3                              Failure to cure was defined as: 1) no surgical resection due to intraope
4         Moderate-to-severe prurigo nodularis was defined as 20 or more nodules, and severe pruritus w
5                                        Cases were defined as 3GC-R-BSI or 3GC-R Gram-negative infecti
6  A universal threshold of 100% G6PD activity was defined as 9.4 U/g Hb, yielding diagnostic threshold
7 lineage analyses, the digit tip blastema has been defined as a population of heterogeneous, lineage-r
8 plex containing a mode III interactor, which is defined as a 14-3-3 interaction with a phosphoserine/
9                                          OME is defined as a chronic low-grade inflammation of the mi
10                                      Frailty is defined as a clinically recognizable state of increas
11                                           It is defined as a dimensional general severity criterion c
12                       An emerging phenomenon is defined as a group of genotypes who exhibit a coheren
13 upling constant in K-type allosteric systems is defined as a ratio of the binding of substrate in the
14 largest residual of the HC/CO(2) correlation is defined as a running loss index (RLI) for each measur
15                                Although pain is defined as a sensory and emotional experience, it is
16                                   Lymphedema was defined as a >= 10% relative increase in arm volume
17                                  Progression was defined as a >=2-step increase in DR severity scale
18                          Histologic response was defined as a 2-point improvement in nonalcoholic fat
19                     Mouse allergen reduction was defined as a 75% or greater decrease in mouse allerg
20                                  Keratoconus was defined as a Belin/Ambrosio enhanced ectasia display
21               For this study, lead poisoning was defined as a blood lead level (BLL) greater than or
22         Adult overweight (including obesity) was defined as a BMI >=25.
23                                Macular edema was defined as a center macular thickness (CMT) >=240 mu
24   The primary endpoint of confirmed response was defined as a composite of all patients presenting wi
25             A disease activity-free interval was defined as a consecutive period in months when treat
26                                 Worse vision was defined as a decrease of more than 2 Snellen lines.
27                                  Equivalence was defined as a difference of 2.5 points or less for IP
28                      Therapy discontinuation was defined as a gap between doses beyond 120 days, and/
29                                         TCFA was defined as a lesion with mean fibrous cap thickness
30                                  Hypotension was defined as a mean arterial pressure (MAP) below 65 m
31 d as 20 or more nodules, and severe pruritus was defined as a mean score of at least 7 for the worst
32                                   Optimal IS was defined as a median of Tac, CsA blood trough levels
33                Favourable functional outcome was defined as a modified Rankin Scale score of 0-2 or a
34 mary outcome, incident noninfectious uveitis was defined as a new diagnosis code for noninfectious uv
35                     Non-invasive progression was defined as a new IPMN, increased main pancreatic duc
36                     Statistical significance was defined as a p value less than 0.10, due to the smal
37  "new persistent postoperative opioid user," was defined as a patient who was opioid-naive before sur
38                              Early clearance was defined as a persistently negative IGRA.
39                       Poor platelet recovery was defined as a platelet count of <=20 000/muL on Day 2
40                                      Frailty was defined as a positive response to >=3 of the followi
41                                        Atopy was defined as a positive skin prick test result (>=3 mm
42                              SPPB impairment was defined as a score of <=10.
43                      Poor cognitive function was defined as a score of less than 18 on the Chinese ve
44                         Metabolic adaptation was defined as a significantly different (lower or highe
45                         Metabolic adaptation was defined as a significantly lower measured compared w
46                                       Myopia was defined as a spherical equivalent of less than or eq
47 ction that exceeded a user-defined threshold was defined as a time point of head motion, which was fo
48 the year preceding elicitation, and viraemia was defined as a viral load of 200 copies per mL or more
49                    An abnormal CSF diagnosis was defined as a white blood cell (WBC) count >20/uL, a
50          Major adverse cardiac events (MACE) were defined as a composite of cardiogenic shock, arrest
51 , and visual acuity recovery and maintenance were defined as a logarithm of minimal angle of resoluti
52 g-term visual field recovery and maintenance were defined as a mean deviation of >-3 at 24 months, an
53            Myopia, emmetropia, and hyperopia were defined as a spherical equivalent of <=-0.5, >-0.5
54                    Abnormal neonatal outcome was defined as abnormal exam and/or abnormal imaging.
55                     Maintenance of remission was defined as absence of clinical and histologic relaps
56                                      Success was defined as achieving a previously determined target
57                                    Adherence was defined as administration of more than 75% of recomm
58                     Donor splitting criteria was defined as age < 40 years, single vasopressor or les
59          Gingival recession defect (GRD) may be defined as an apical migration of the gingival margin
60 onal area of unitary pooled activity (FAUPA) is defined as an area in which the temporal variation of
61 " for dejection or negative emotional state) is defined as an increase in intensity of the constellat
62                                  Ferroptosis is defined as an iron-dependent form of regulated cell d
63                                          AKI was defined as an absolute or a relative increase in ser
64                       Treatment modification was defined as an addition to or change in drug therapy
65                                          SAH was defined as an adult height <= 2 standard deviation s
66                                      Burnout was defined as an affirmative response to two single-ite
67                          New significant AKI was defined as an AKI-stage increase of two or more (Kid
68                               Immunogenicity was defined as an anti-drug antibody titer >=10 AU/mL us
69                         Treatment resistance was defined as an antidepressant treatment record level
70                                         RORA was defined as an area of (1) hypertransmission, (2) dis
71 ting wave energy; a normal exercise response was defined as an increase in accelerating wave energy f
72      Intraocular pressure spike complication was defined as an increase in IOP in the operated eye at
73                  Symptomatic KOA progression was defined as an increase in or remaining in 1 of the 2
74                           Functional decline was defined as an increase in the number of activities o
75                      Hospitalization for CVD was defined as an inpatient or emergency department disc
76                             Surgical success was defined as an intraocular pressure (IOP) of 5-20 mm
77 s, heparin-induced thrombocytopenia negative was defined as an optical density less than 1.0 and hepa
78                               PA consistency was defined as any combination of >= 75 minutes of vigor
79                                          BCP was defined as any detectable first serum PSA value afte
80                            Myocardial injury was defined as any elevation in cardiac troponin at the
81                               Failure of SLT was defined as any further glaucoma procedure post-SLT o
82                             Preoperative use was defined as any opioid prescription filled in the yea
83                    Adverse clinical outcomes were defined as any possible complication of meningitis,
84                            Recurrences of VT were defined as appropriate implantable cardioverter def
85                            Persistent asthma was defined as asthma requiring use of controller medica
86                                           MM was defined as at least 3 coexistent morbidities of high
87                               Frequent AECRS was defined as at least 4 episodes over a 12-month perio
88 compliance and rates of noncompliance, which were defined as at least 1 missed visit or exiting the s
89                   Successful collapse of AHP was defined as being <=10 degrees .
90                                       Low IS was defined as below the thresholds of optimal IS.
91                             Tumor recurrence was defined as biopsy-proven vital tumor at the initial
92            Complex fractionated electrograms were defined as bipolar electrograms with >=5 directiona
93                                     Bleeding was defined as Bleeding Academic Research Consortium (BA
94                   Procedure-related bleeding was defined as Bleeding Academic Research Consortium typ
95                            Recipient obesity was defined as body mass index (BMI) >35 adjusted for as
96                      Historically, SSCs have been defined as bone marrow-derived cells with inconsist
97  find that open chromatin regions (OCRs) can be defined as broadly permissive or dynamic in a locus-s
98                                      Outcome was defined as cardiovascular death, heart transplantati
99                         Advanced HIV disease was defined as CD4 of <200 cells/muL or acquired immune
100              Human natural killer (NK) cells are defined as CD56(+)CD3(-).
101                                          TNT was defined as chemotherapy using cycles of induction an
102 onders and mean arterial pressure-responders were defined as CI >=10% and mean arterial pressure >=10
103                              Active clusters were defined as clusters including internal nodes from 2
104                                  The CS-CMVi was defined as CMV viremia and/or disease necessitating
105 programmed death ligand 1 (PD-L1) expression was defined as combined positive score (CPS) >= 10.
106                                     Efficacy was defined as complete response (CR) rate on end-of-tre
107                                          DUP was defined as days from first psychotic symptom to firs
108                                Poor recovery was defined as death by 30 days postdischarge or an incr
109                         Unfavourable outcome was defined as death or significant grey matter injury o
110           Symptomatic venous thromboembolism was defined as deep vein thrombosis, pulmonary embolism,
111            Annualized Delta transformed CACS was defined as Delta transformed CACS divided by the int
112                                  Proteinuria was defined as Delta urine protein >=300 mg/24 h at 1 ye
113             Deviation from chronological age was defined as "delta age".
114                         Invasive progression was defined as development of invasive cancer in the rem
115 ived filtering and interpretation procedures were defined as diagnostic variants.
116                 Mean arterial pressure (MAP) was defined as diastolic BP plus 1/3 (systolic BP - dias
117 terogeneous exposure associations (HEAs) can be defined as differences in the association of an expos
118 tially reduce chronobiological strain, which is defined as disruption or misalignment within the circ
119   Among the 1,379 T2 lesions identified, 512 were defined as DPA-active and 258 as DPA-inactive.
120            A reactive hyperemic index <=1.35 was defined as ED.
121                                 Incident CKD was defined as eGFR <60 ml/min per 1.73 m(2) with eGFR d
122            Clinically relevant CMV infection was defined as either plasma CMV DNAemia >= 1000 IU/mL w
123                   Heightened stress exposure was defined as exposure to at least one chronic stressor
124                            Induction failure was defined as failure to achieve a partial response (PR
125                                   Early COPD was defined as FEV(1)/FVC less than the lower limit of n
126                                Three cohorts were defined as follows: 1) ICU survivors; 2) one-year s
127                           Airway obstruction was defined as forced expiratory volume in 1-second (FEV
128                             Primary outcomes were defined as frequency of complications following sta
129 e primary care record, and eczema prevalence was defined as fulfilment of criteria for active eczema
130                                        Cases were defined as GAS isolated from a normally sterile sit
131                             Invasive disease was defined as GBS isolated from a normally sterile site
132               Single-parent expression (SPE) is defined as gene expression in only one of the two par
133 resentation and outcome 1 year after surgery were defined as good or satisfactory if intraocular pres
134 ibrosis and inflammation, where inflammation was defined as &gt;14 infiltrating cells/mm(2).
135                                   Recurrence was defined as &gt;30 seconds of AF, atrial flutter, or atr
136                                      Frailty was defined as &gt;= 3 of the following: low lean mass, exh
137                                          CHD was defined as &gt;=1 inpatient code or >=2 outpatient CHD
138                           Adenovirus viremia was defined as &gt;=2 consecutive viral loads (VLs) >=1000
139                                          RIC was defined as &gt;=2 encounters per year, >=90 days apart,
140                                Elevated FeNO was defined as &gt;=25 parts per billion.
141                                      Anaemia was defined as haemoglobin less than 130 g/L for men and
142                                      Frailty was defined as having >=3 of the following 5 criteria fr
143                                      Frailty was defined as having >=3 of the following 5 criteria fr
144                                 Microcephaly was defined as having a head circumference Z score <-2 a
145                               Severe wasting was defined as having a weight for length z score (WLZ)
146                   Positive depression status was defined as having any of the following: elevated dep
147                                      Frailty was defined as having at least 3 of the following 5 crit
148                                      Allergy was defined as having symptoms from at least 1 allergic
149                   Cardiometabolic clustering was defined as having three or more risk factors out of
150            At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway
151                                     Diabetes was defined as HbA1c of >=6.5% and/or current diabetes m
152      The severity of localized periodontitis was defined as healthy (n = 42), Stage I (initial) (n =
153                                Objective AEs were defined as hepatic and objective muscular AEs.
154 re 110 interpreting radiologists, of whom 24 were defined as high-volume readers (ie, those who inter
155         The primary outcome of this analysis was defined as histopathologically confirmed CIN2+ or ce
156                                        Cases were defined as HIV infections diagnosed during 2015-201
157    This fact suggests that RFs of SDs cannot be defined as homogeneous sensory zone driven by a linea
158        Disproportionately minority hospitals were defined as hospitals having twice the relative mino
159                                      Success was defined as improvement in 3 Early Treatment Diabetic
160                                  RV recovery was defined as improvements in central venous pressure,
161         Primary angle closure disease (PACD) was defined as inability to visualize pigmented trabecul
162          For the primary analysis, remission was defined as inactive uveitis while off treatment at a
163           Daily numbers of 'crisis episodes' were defined as incident inpatient, home treatment team
164                                        Cases were defined as incident TB or all-cause death within 48
165                                Relapse of ME was defined as increase in macular thickness to >=240 mu
166            A chronic or resolved PAMM lesion was defined as inner nuclear layer thinning with outer p
167                              Adverse outcome was defined as intensive care unit (ICU) admission or de
168                        Conduction delay (CD) was defined as interelectrode conduction time of 7 to 11
169                                      CTO-PCI was defined as intervention of a 100% occluded coronary
170           The cumulative failure of the AADI was defined as intraocular pressure (IOP) >18 mm Hg or n
171                                      Success was defined as intraocular pressure (IOP) between 6 and
172                                 Poor outcome was defined as invasive ventilation and/or death.
173                          Refractory glaucoma was defined as IOP >21 mmHg on maximum tolerated glaucom
174      Selective laser trabeculoplasty success was defined as IOP decrease of 20% or more from baseline
175  year of hospital discharge; postpublication was defined as January 2017 onward (July 2017 for effect
176  early, whereas those between 16 to 24 hours were defined as late.
177                Conjunctival biopsy locations were defined as "lesional," "perilesional," and "nonaffe
178                                      Failure was defined as less than 20% reduction of IOP from medic
179                                  DAT deficit was defined as less than 65% of putamen striatal binding
180 maging, and nonalcoholic fatty liver disease was defined as liver fat fraction >=5.0%.
181 cutoff value for strut coverage by OCT which was defined as luminal endothelial cells with 2 ablumina
182                             LV full recovery was defined as LVEF >=55%.
183                         Diagnostic allergens are defined as medicinal products in the EU.
184                             Metabolic health was defined as meeting less than 2 of the following 4 cr
185                                Microplastics are defined as microscopic plastic particles in the rang
186                          Incident depression was defined as minimal depressive symptoms at baseline a
187                                           SR was defined as modified thrombolysis in cerebral ischemi
188                           External migration was defined as moving (i.e., change in residency) into o
189                                        ASCVD was defined as myocardial infarction, coronary or caroti
190                                         MACE was defined as myocardial infarction, late (>180 days) r
191                                           HS was defined as new onset altered mental status after tra
192                                      Relapse was defined as new or reappearing symptoms or worsening
193                          Active surveillance was defined as no definitive treatment within the first
194                      Potential off-label use was defined as no recorded diagnosis of either COPD or a
195               Long non-coding RNAs (lncRNAs) are defined as non-protein-coding transcripts that are a
196                                       Myopia was defined as non-cycloplegic subjective spherical equi
197                                         POAF was defined as occurrence of postcardiac surgery atrial
198 tion theory, an efficient retinal code could be defined as one that reduces redundancy to communicate
199                                     Rhinitis was defined as one or more episodes of sneezing, runny a
200                               A dominant LAD was defined as one that was wrapped around the left vent
201 keholder groups combined) results, consensus was defined as outcomes scoring greater than 90% "critic
202 ransmission by P. duboscqi, this DNA vaccine was defined as partially protective, in the context of L
203              Isolated traumatic brain injury was defined as patients with a head Abbreviated Injury S
204                                        Cases were defined as patients with at least a four-fold incre
205                         Exercise intolerance was defined as peak oxygen uptake < 85% predicted from m
206 tive therapy, a successful treatment outcome was defined as peri-implant health with a reduced suppor
207                                  Beta bursts were defined as periods exceeding the 75th percentile am
208 CKD, whereas end-stage kidney disease (ESKD) is defined as permanent kidney failure.
209                     Modes of DAPT cessations were defined as physician-guided DAPT discontinuation, b
210                                 Coagulopathy was defined as platelets lower than 150 x 109/L, interna
211                          Respiratory failure was defined as PO(2)/FiO(2) ratio of <=40 kPa.
212 ve predictive value (PPV) occurred when iPET was defined as positive if the Deauville score was 4-5 (
213                                Complications were defined as postoperative events due to the GDD that
214                                       A case was defined as PPV23 serotype-specific pneumococcal pneu
215                                 Hypertension was defined as prescription of blood pressure-lowering d
216 outcome was time to progression; progression was defined as PSA level of 10 ng/mL or greater, PSA dou
217 not failed but required glaucoma medications were defined as qualified successes.
218 itive and consensus-negative interpretations were defined as qualitative agreement in at least 3 of t
219                            Treatment success was defined as rCDI prevention through 8 weeks after tre
220                    Early pubertal maturation was defined as reaching a certain pubertal stage earlier
221                              Pouch phenotype was defined as recurrent-acute pouchitis (n = 6), chroni
222                                De-escalation was defined as reduction in either the number of antibio
223           Following this view, LCRs can also be defined as regions showing composition bias.
224                                   Inactivity was defined as requirement for assistance with activitie
225                                         USBR was defined as resection within 6 months of diagnosis.
226       Single surgery anatomic success (SSAS) was defined as retinal attachment without ongoing tampon
227           The global test-retest variability was defined as root mean square deviation (RMSD) of TD v
228                 Oropharyngeal testing policy was defined as routine universal testing when >=85% of c
229                                           TC was defined as same-nodule histologic malignancy.
230                            Allergic rhinitis was defined as sensitisation and self-reported nasal sym
231                              Immune response was defined as seroconversion from seronegative (<1:8) a
232         Severe neurodevelopmental impairment was defined as severe cerebral palsy or a composite moto
233             The diagnosis of endophthalmitis was defined as severe intraocular inflammation that nece
234                              Anion foldamers are defined as single- or multistrand complexes-often he
235                   Severe acute kidney injury was defined as stage 2/3 acute kidney injury.
236            The primary outcome of BP control was defined as systolic BP level lower than 140 mm Hg an
237                                         ADHF was defined as systolic or diastolic dysfunction requiri
238                        An AUC24/MIC of >=125 was defined as target ratio.
239                              Vaccine failure was defined as TBE despite adherence to the recommended
240                                      Fast VT was defined as TCL <333 milliseconds (rate >180 bpm).
241                   Significant liver fibrosis was defined as TE >=7.1 kPa.
242 he group recommended that effective coverage be defined as the proportion of a population in need of
243 (1/2) and delta(RA)/(3)(1/2), with delta(RA) being defined as the difference between the maximum and
244                     Recurrent pregnancy loss is defined as the failure of two or more clinically reco
245 e proton affinity (PA) of a neutral molecule is defined as the negative of the enthalpy change for th
246             The term diabetic cardiomyopathy is defined as the presence of abnormalities in myocardia
247 e implementation, where the outcome variable is defined as the ratio of total sickness hours over the
248            The fidelity of quantum transport is defined as the transmission performance of an ensembl
249                                    Radiomics is defined as the use of automated or semi-automated pos
250  The Environmental Biosafety Criterion (EBC) was defined as the absence of fungal and bacterial conta
251                        Metabolic flexibility was defined as the change in 24-h RQ from EBL during fas
252  surgery, and early brachial artery dilation was defined as the change in postoperative arterial diam
253                    The optimal ELN threshold was defined as the cut-point associated with a 95% proba
254 h all measurements were grouped and baseline was defined as the day of injection, and thus the pharma
255                         Incident visual loss was defined as the development of or worsening of visual
256                       Response to naltrexone was defined as the difference in craving and the differe
257                               Change in EDSS was defined as the difference in EDSS between attack and
258                             Eczema incidence was defined as the first-ever diagnosis of eczema record
259                               Elevated Lp(a) was defined as the highest race-specific quintile.
260                        The date of diagnosis was defined as the index date.
261 ne, and nitric oxide synthase (NOS) activity was defined as the inverse of FBF reserve to N(G)-monome
262                 Noninferiority of GMT ratios was defined as the lower bound of the 2-sided 95% confid
263                               Noninferiority was defined as the lower limit of the 95% CI for the dif
264                         Cognitive impairment was defined as the lowest tertile in the main analysis a
265                           Anatomical success was defined as the maintenance of retinal reattachment w
266                                 MaxLCBI(4mm) was defined as the maximum LCBI within any 4-mm-long seg
267      For each participant, the index episode was defined as the most recent syphilis episode for whic
268                           Extubation failure was defined as the need for mechanical ventilation withi
269                                    Home time was defined as the number of days alive and spent outsid
270           Worsening traction after treatment was defined as the occurrence within 6 months of worseni
271                                  Superiority was defined as the posterior probability of an odds rati
272                      A true-positive finding was defined as the presence of a pathology-confirmed can
273                         Family history of AF was defined as the presence of AF in a first-degree rela
274                                 Plateau iris was defined as the presence of all the following UBM cri
275                                          UMI was defined as the presence of late gadolinium enhanceme
276                                      The PPV was defined as the proportion of patients who had true-p
277            GA perimeter-adjusted growth rate was defined as the ratio between GA area growth rate and
278                                          EFS was defined as the time from random assignment to the da
279                 Vasopressor dosing intensity was defined as the total vasopressor dose infused across
280 -term variability during a particular period was defined as the variability in IOP measurements obtai
281                        Long-term variability was defined as the variability in IOP measurements obtai
282                  Cut-off points for symmetry were defined as the 95th percentile of the absolute inte
283                             Changes to costs were defined as the cost of implementing the bundle minu
284                                          SAE were defined as the occurrence of >=1 moderate, major, o
285                          High mutation rates were defined as the top 10% of the mutation rate, utiliz
286                                   Responders were defined as those alive without HF hospitalization a
287                             Super-responders were defined as those alive without HF hospitalization a
288                         High-impact journals were defined as those in the top 5% of all journals.
289             Patients with confirmed COVID-19 were defined as those with a positive SARS-CoV-2 test.
290            Health care-associated infections were defined as those with onset in a health care facili
291              Pulmonary-specific inflammation was defined as total glycolytic activity (TGA) on [18]F-
292  A meaningful difference in ICD failure rate was defined as twice (or more) the lead failure rate obs
293                     Asymptomatic bacteriuria is defined as two consecutive voided specimens (preferab
294          Hypercoagulable thromboelastography was defined as two or more hypercoagulable parameters.
295      Allergic rhinitis to grass pollen (ARg) was defined as upper airway symptoms during grass pollen
296             Household air pollution exposure was defined as use of polluting fuels (coal, wood, charc
297             Serum 25(OH)VD levels < 30 ng/mL were defined as VD insufficiency/deficiency.
298                            Visual impairment was defined as visual acuity (VA) of > 0.3 logarithm of
299                                           PV was defined as Vt <=8 ml/kg predicted body weight and po
300                                    A cICA-PO was defined as when single phase computed tomography ang

 
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