ライフサイエンスコーパス: be down-regulated in

1 Clinically, PTPRF was down-regulated in 42% HCC (37/89), 67% gastric cance

2 p120ctn is down-regulated in 60% of ESCC tumors, whereas EGFR is

3 DKK4 was down-regulated in 67.5% of HCC cancerous tissues.

4 Cyclin D3 is down-regulated in a dose-dependent manner in beta cel

5 We show here that TrkC expression is down-regulated in a large fraction of human colorecta

6 In this study we show that CDC73 is down-regulated in a majority of OSCC samples.

7 Here, we show that miR-124 is down-regulated in a panel of different grades of glio

8 oplasmic tRNAs tK(UUU), tQ(UUG) and tE(UUC), is down-regulated in a proteasomal dependent fashion.

9 xpression of glutathione peroxidase 3 (GPx3) is down-regulated in a variety of human malignancies.

10 We found that latexin was down-regulated in a variety of leukemia and lymphoma

11 Salt-inducible HSFA6b expression was down-regulated in ABA-insensitive and -deficient mut

12 ression status, and the majority of the rest were down-regulated in abiotic stresses and up-regulated

13 per pilosebaceous unit of normal human skin, is down-regulated in acne.

14 proximately miR-27a approximately miR-24-2), was down-regulated in acute leukemia cell lines and prim

15 mma (PPAR-gamma) and downstream target genes were down-regulated in adipose tissue from participants

16 Notably, when Alk4 was down-regulated in adult wild-type mice, muscle mass

17 MICA expression was down-regulated in advanced fibrosis stages.

18 ected horses suggested that MUTYH expression is down-regulated in affected horses.

19 Interestingly, we find that Gish expression is down-regulated in aging guts and that increasing Gish

20 iogenesis, including c-MYC, c-MYB, and VEGF, were down-regulated in association with a decline in hyp

21 We found that expression of miR-3189-3p was down-regulated in astrocytoma and glioblastoma clini

22 ding 443 that were up-regulated and 373 that were down-regulated in ATH tissues.

23 ement (ABRE) element within their promoters, were down-regulated in AtVIP2 overexpressor lines.

24 trahydrofolate reductase (MTHFR) gene, which is down-regulated in bm2 mutant plants.

25 and qPCR indicated that the expression of FT is down-regulated in both OsbHLH068-overexpressing Arabi

26 e 3 (Sec14l3) - a putative target of Creb1 - was down-regulated in both asthma models and in NHBE cel

27 hese targets, such as Axin2, Fgf8 and Wnt3a, is down regulated in Brachyury mutant embryos and we dem

28 dings demonstrate that mGlu2 mRNA expression is down-regulated in brain cortical regions of 5-HT2A kn

29 Finally, we show that CDKN3 protein is down-regulated in brain tumors.

30 trates that SOX7 mRNA and protein expression are down-regulated in breast cancer tissues and cell lin

31 MiRNAs 125b and 145, which are down-regulated in breast cancer, were below the 1000

32 Here, we show that SOD2 itself is down-regulated in breast cancer cell lines.

33 expressed on normal breast epithelial cells is down-regulated in breast cancer.

34 a possible tumor suppressor microRNA (miR), is down-regulated in breast tumors compared with normal

35 F, Has2 and Ccl5 were up-regulated and Ccl11 was down-regulated in CAF in co-culture.

36 Ten genes (14 probe sets) were down-regulated in CAF, including the pluripotency t

37 one in cancer; these tended to be genes that are down-regulated in cancer and that function in develo

38 In contrast, the ASncmtRNAs are down-regulated in cancer cells.

39 hesized in normal gastrointestinal cells but are down-regulated in cancer cells.

40 rises a portion of the PcG target genes that are down-regulated in cancer.

41 cbl1 shoots, while a different set of genes were down-regulated in cbl1 but not in WT roots.

42 Our findings demonstrate that miR-494 is down-regulated in CCA and that its up-regulation indu

43 ed with cancer cell invasion and metastasis, were down-regulated in cell homogenates following cystat

44 mediated by the DNA methylase, DNMT3A, which is down-regulated in cells lacking p38alpha, but once re

45 Here we show that miR-148a is down-regulated in cells with acquired TRAIL-resistanc

46 hatidylinositol 3-kinase/Akt activation that was down-regulated in cells that lack annexin-A6, one of

47 FOXO1 was down-regulated in cHL cell lines, whereas it was exp

48 ich miR-494, one of the miR species found to be down-regulated in cholangiocarcinoma (CCA), participa

49 c cells, is a candidate tumor suppressor and is down-regulated in chronic lymphocytic leukemia (CLL).

50 ral drug metabolism and BA transporter genes were down-regulated in Cic-L(-/-) liver, and that BA was

51 ponse were up-regulated, and apoptosis genes were down-regulated in circulating immune cells.

52 teractions and NK cell-mediated cytotoxicity were down-regulated in cKO decidua compared with control

53 ed from distinct genes of pre-tRNA(His), and are down-regulated in CLL 3- to 5-fold vs. normal B cell

54 c stress responses, as kaempferol glycosides were down-regulated in cml42, and impaired in ultraviole

55 ght to determine the mechanism by which BMP4 is down-regulated in CNV.

56 Our results demonstrate that SNRK is down-regulated in colon cancer and inhibits colon can

57 Interestingly, the proapoptotic protein p73 is down-regulated in colon cancer cells expressing p53.

58 Moreover, TFAM expression was down-regulated in comparison to the control (p < 0.0

59 In Salix, Rubisco activase transcripts were down-regulated in contaminated trees across all 10

60 ferator-activated receptor-gamma (PPARgamma) was down-regulated in control animals after AMI and up-r

61 re transcribed from the same RNA hairpin and are down-regulated in CRC cells.

62 miR-28-5p and miR-28-3p were down-regulated in CRC samples compared with normal

63 croRNAs (miRNAs) that inhibit CSC growth and are down-regulated in CSCs.

64 Further, SMAD/TGF-beta1 signaling was down-regulated in CSF plasmablasts/plasma cells.

65 of the transcription factor EB (TFEB), which was down-regulated in cystinosis.

66 g ducts of mice and rats, and its expression is down-regulated in Dahl salt-sensitive rats fed a high

67 In vivo, expression of Fam65b was down-regulated in developing zebrafish to determine

68 cells (EPC) to areas of neovascularization), is down-regulated in diabetic wounds.

69 Consistently, hepatic Sort1 was down-regulated in diabetic mice, which was partially

70 Kbtbd2 was down-regulated in diet-induced obese insulin-resista

71 Analysis revealed that this target gene set is down-regulated in DS-AMKL patients highly expressing

72 regulated, whereas tissue inhibitors of MMPs are down-regulated, in dystrophic muscle of mdx mice.

73 rized, the mechanism by which Rag expression is down-regulated in early B cell development has not be

74 and other angiogenic regulatory transcripts were down-regulated in Elavl1Mo KO BMDMs.

75 3GalT4 gene, responsible for Gg4 expression, is down-regulated in EMT; and Gg4 has a regulatory funct

76 posterior localization of Osk in the oocyte, were down-regulated in enok mutants.

77 miR-214, and LHX6 expression was detected to be down-regulated in erlotinib-resistant HCC827 cells.

78 canonical Wnt/beta-catenin signaling pathway was down-regulated in ERMS cells compared with normal my

79 induced MMP-9 and MMP-13 promoter activities were down-regulated in ETS-1 siRNA-transfected cells.

80 we show that major antioxidant defense genes are down-regulated in FA patients, and that gene down-re

81 anscript; miR-198 expression in healthy skin is down-regulated in favor of FSTL1 upon wounding, which

82 se element and activate antioxidant defense, is down-regulated in FECD endothelium.

83 how that the GATA1 and GATA1-dependent genes are down-regulated in fetal liver of SENP1 KO mice.

84 Two placode markers, Fgf4 and Foxi3, were down-regulated in Fgf3(-)(/)(-);Fgf10(-)(/)(-) embr

85 The expression of miR-101 was down-regulated in fibrotic lungs from patients with

86 We have shown that peach PpeS6PDH gene is down-regulated in flower buds after dormancy release,

87 important role in tumor cell proliferation, were down-regulated in Foxm1-deficient PCa tumors in viv

88 In clinical samples, miR-125b-5p was down-regulated in gallbladder cancer whereas Bcl2 wa

89 an upstream autophagy inducer, was found to be down-regulated in GBM.

90 ow binding of BCL6 in their genomic loci and are down-regulated in GC B cells.

91 In addition, Camta1, Camta2, and Nkx2-2 were down-regulated in GK rat islets, and knockdown of C

92 in neural development and has been shown to be down-regulated in glioma and medulloblastoma, suggest

93 Other glossy genes tended to be down-regulated in glossy mutants; by contrast stress-

94 production of reactive oxygen species (ROS) are down-regulated in GMP synthetase mutant larvae.

95 nd the expression of many Srebp target genes are down-regulated in gonzo mutant livers.

96 contrast to other cancers, PICK1 expression is down-regulated in grade IV astrocytic tumor cell line

97 hetic enzyme cystathionine-gamma-lyase (CSE) is down-regulated in growth-restricted placentas.

98 itrite levels and apelin and NOS3 expression were down-regulated in HAPE-p (P < 0.001).

99 analyzed miR-133b expression and found it to be down-regulated in HCC patient samples and induced in

100 (GNMT) catabolizes SAMe, but its expression is down-regulated in HCC cells.

101 We report that miR-1271 expression is down-regulated in HCC tumor samples and inversely cor

102 metabolism of many carcinogens and drugs and is down-regulated in HCC.

103 inducer of hepatocytic differentiation that is down-regulated in HCC.

104 miR-375 was down-regulated in HCC cells and tissues; it inhibite

105 ets of miR-216a/217, and both PTEN and SMAD7 were down-regulated in HCC.

106 lated in the striatum of mouse HD models and is down-regulated in HD individuals.

107 that play a pivotal role in memory function, were down-regulated in head trauma-related disorders.

108 -A), the primary signaling receptor for BNP, is down-regulated in heart failure.

109 mMRP-5 (all orthologs of HRGs in C. elegans) are down-regulated in heme-treated B. malayi, as compare

110 RNA (miR)-122, a bona fide tumor suppressor, is down-regulated in hepatocellular cancer (HCC).

111 Interestingly, 16 of these 18 genes were down-regulated in high-grade glioma.

112 ysaccharides and related regulatory systems, was down-regulated in host-like media when compared to M

113 We demonstrate that these genes are down-regulated in HPRT-deficient SH-SY5Y cells and t

114 rce this result, we also show that Tif1gamma is down-regulated in HSCs during aging in 20-mo-old wild

115 sis, and expression of IKKalpha was found to be down-regulated in human and murine skin squamous cell

116 We found expression of TFF2 to be down-regulated in human PDAC by hypermethylation of i

117 the mitotic kinases, Aurora A and Plk1, that is down regulated in human seminoma.

118 We also found that expression of miRNA-200b is down-regulated in human breast cancer during lymph no

119 we showed that caveolin-1 (Cav-1) expression is down-regulated in human breast cancer-associated fibr

120 Moreover, NCoR is down-regulated in human hepatocarcinomas and in the m

121 Expression of alpha1-ACT is down-regulated in human hepatocellular carcinoma (HCC

122 More important, FRNK expression is down-regulated in human IPF, and down-regulation of F

123 Remarkably, TP53INP1 is down-regulated in human IPMN.

124 glandin E2 (PGE2), through its receptor EP4, is down-regulated in human systemic inflammatory disease

125 Notably, SAT1 expression is down-regulated in human tumors, and CRISPR-cas9-media

126 PER3 was down-regulated in human HCCs, compared to peritumoro

127 results, both RAD52 and RAD23B were found to be down-regulated in hypoxia, but in both cases, the hyp

128 Muscular secreted frizzled-related protein 2 is down-regulated in ICU-acquired weakness patients and

129 ne expression data sets indicates that DOT1L is down-regulated in idiopathic DCM patient samples comp

130 BER genes NEIL3 was down-regulated in IFN-treated patients.

131 2',5'-oligoadenylate synthetase (2',5'-OAS) were down-regulated in IFN-alpha-treated HEV-A549 cells.

132 proteins and enzymes in fatty acid synthesis were down-regulated in IL-10(-/-) mice.

133 TIMP-3 is down-regulated in inflamed intestine of patients with

134 We previously showed that aPKC is down-regulated in intestinal epithelia under inflamma

135 , (ii) murine TETs, especially TET2 and TDG, are down-regulated in islets during postnatal differenti

136 cates that basic processes of DNA metabolism are down-regulated in its absence, and the blocked T-cel

137 up-regulated genes in JGM-treated BPH, which were down-regulated in JGM-treated WBPH.

138 Critical actin cytoskeletal genes are down-regulated in KO megakaryocytes.

139 defense priming in systemic plant immunity, was down-regulated in leaves by joint stress and conferr

140 ogy practice; and CPS1 expression appears to be down-regulated in liver cancer tissue and cell lines.

141 We found that miRNA-122 (miR-122) is down-regulated in liver biopsy specimens of patients

142 IRF5 in HCV-induced HCC, as IRF5 expression was down-regulated in livers from HCV-positive versus HC

143 ype mice, whereas enzymes that synthesize BA were down-regulated in livers of Cftr-/- mice.

144 -1271, miR-145, miR-99b, miR-191 and miR-10b were down-regulated in low RFI pigs.

145 RNA processing and the endoplasmic reticulum were down-regulated in LRRK2 G2019S mice compared with K

146 TGFbeta pathway, including pSMAD2 and pERK, were down-regulated in LTBP4 mutant human dermal fibrobl

147 We found that PPARgamma was down-regulated in lung tissue and epithelial cells o

148 SHP2 was down-regulated in lungs and lung fibroblasts obtaine

149 Leukotriene B(4) was down-regulated in M2 (668 +/- 81 vs 351 +/- 39 pg/2.

150 Consistently, hCDC14A is down-regulated in many tumor tissues and reduced hCDC

151 We demonstrate that miR-9 expression is down-regulated in MCF-7 and MDA-MB-231 breast cancer

152 of a number of known ERalpha-regulated genes was down-regulated in MED1-mutant mammary epithelial cel

153 xpressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tum

154 Herein, we demonstrate that miR-200c is down-regulated in melanomas (primary and metastatic)

155 tor of tumor metastasis in MDSCs, NGP, which is down-regulated in metastatic conditions.

156 xpressed in many cancers, including RCC, and is down-regulated in metastatic versus primary ccRCC.

157 Also, ANGPTL7 was down-regulated in metastatic liver colonies of color

158 miR-126 was down-regulated in metastatic versus primary tumors a

159 :0)-ceramide was gradually reduced and CerS6 was down-regulated in mitochondria, thereby implicating

160 Additionally, miR-126, miR-145, and miR-335 were down-regulated in monolayers of tissue-cultured cho

161 nuclear factor 4A-driven gene network, which was down-regulated in mouse hepatocyte nuclear factor 4A

162 The expression of the fbpB gene is found to be down-regulated in Mtb cells upon infection when these

163 in A, and Growth factor-independent 1 (Gfi1) were down-regulated in Mtgr1(-/-) whole intestines and M

164 ed that all classes of floral homeotic genes are down-regulated in mtnam mutants.

165 nits and membrane translocation of p47(phox) are down-regulated in murine and human G6PC3-deficient n

166 Many cell wall related genes are down regulated in mus-3 mul-1.

167 he activity of the insulin signaling pathway was down-regulated in myocytes isolated from the femoral

168 is a widely distributed nuclear lncRNA that is down-regulated in NAFLD.

169 tein claudin 1 (Cldn-1) has been reported to be down-regulated in nonlesional skin of atopic dermatit

170 e is up-regulated in Wake and REM sleep, and is down-regulated in NREM sleep.

171 regulate oxidative stress in the lean state are down-regulated in obesity as a consequence of inflam

172 arkers (Lgr5, Olfm4, Smoc2, Msi1, and Ascl2) were down-regulated in organoids incubated with etomoxir

173 e 2 of the gibberellin biosynthesis pathway, is down-regulated in OsbZIP48(OE) and up-regulated in Os

174 Superoxide dismutase 2 (SOD2) is down- regulated in osteoarthritis (OA).

175 -time RT-PCR results demonstrated that Satb2 was down-regulated in Osx-null calvaria.

176 RT-PCR results revealed that VEGF expression was down-regulated in Osx-null calvarial cells and that

177 wo of the markers of malignant melanoma that were down-regulated in Panx1-KD cells.

178 We found that pulmonary PPARgamma is down-regulated in patients with IPF.

179 The functionally essential sGC beta1-subunit was down-regulated in patients with COPD and in CS-expos

180 SMARCD1 was down-regulated in patients with non-small cell lung

181 proteins, and B- and T-cell differentiation were down-regulated in patients with FHL.

182 t-tagged miR in cells where PLCbeta1 or C3PO were down-regulated in PC12 cells and find substantial d

183 which encodes a stathmin family protein and is down-regulated in PD brains, as a key regulator funct

184 Over 90% (n = 1767) of these genes were down-regulated in PDX models and enriched in stroma

185 NEDD4 was down-regulated in persons taking statins, and simvas

186 A fifth miRNA, mir-6722, was down-regulated in persons with AD and mild cognitive

187 ies in PGK mutants showed that PGK1 and PGK3 were down-regulated in pgk3.2 and pgk1.1, respectively.

188 ession of several key slit diaphragm protein was down regulated in pGR KO mice.

189 trophoblast and that ETC protein expression is down-regulated in placentas of infants with intrauter

190 2-mediated oxidative stress response pathway were down-regulated in PMNs of diseased patients.

191 vels in the pre-TCR signaled thymocytes, and is down-regulated in post-beta-selection thymocytes.

192 olved in gametogenesis in Chlamydomonas pCRY is down-regulated in pregametes and gametes, and in the

193 xin 43, and cyclooxygenase-2) and prolactins are down-regulated in pregnant smtnl1(-/-) mice.

194 arbonate secretor in the human biliary tree, is down-regulated in primary biliary cholangitis.

195 We show that MAOA is down-regulated in primary NPC tissues and its down-re

196 ble role of CTLA4 in CLL pathogenesis, CTLA4 was down-regulated in primary CLL cells.

197 We found that macroH2A1.1 mRNA was down-regulated in primary colorectal cancer samples

198 We found that Ctgf mRNA was down-regulated in primary sternal chondrocytes from

199 181a, miR-199a-5p) predicted to target GRP78 are down-regulated in prostate, colon and bladder tumors

200 xpressed in actively proliferating cells and are down-regulated in quiescent cells.

201 lly, we demonstrated that phosphorylated Akt is down-regulated in Raji cells transduced with EPHB4.

202 tive regulator of adipocyte differentiation, is down-regulated in RCC and shows a differential expres

203 CBFs and CBF regulon genes were down-regulated in rdm4 but not nrpe1 (the largest s

204 cial role in muscle growth and regeneration, was down-regulated in regenerating Trpc1(-/-) muscles.

205 HBI1 expression is down-regulated in response to different PAMPs.

206 deacetylase and activator of fat oxidation, is down-regulated in response to high fat feeding, the r

207 hich surface expression of the Vbeta5(+) TCR is down-regulated in response to Mtv-8 and recombination

208 primary methyltransferase acting on H3K9me2, was down-regulated in response to (*)NO, and changes in

209 In human HSCs, BAMBI expression was down-regulated in response to LPS and TNF-alpha.

210 owed high levels of LRRc17 expression, which was down-regulated in response to the pro-osteoclastogen

211 , PUNCTATE VASCULAR EXPRESSION1 (PVE1), that is down-regulated in rgd2-R mutant apices.

212 ntified a serine protein kinase, SRPK3, that was down-regulated in RMS cells and found that expressio

213 -glucose co-transporter 2 (Sglt2) expression was down-regulated in RPTs of both male and female KO mi

214 In prior work, we identified 48 genes that were down-regulated in SCCs compared with high-grade squ

215 Moreover, miR-26a is down-regulated in serum exosomes and islets of obese

216 Importantly, we show that iso3, known to be down-regulated in several cancers, competes with RBBP

217 VILIP-1 expression is down-regulated in several types of human cancer.

218 BPdelta, and in contrast to cyclin D1, Cdc27 was down-regulated in several breast cancer cell lines,

219 The Cancer Genome Atlas and found that MBNL1 was down-regulated in several common cancers.

220 tate histidine exonuclease whose transcripts are down-regulated in sexual ovules entering meiosis whi

221 he chemokine CCL5 was up-regulated and CCL11 was down-regulated in SF in co-culture.

222 ibitor, secreted frizzled-related protein 2, was down-regulated in skeletal muscle of ICU-acquired we

223 show that the p53-induced genes DDB2 and p21 are down-regulated in skin cancer, and in the mouse mode

224 vity of ATR, which regulates the cell cycle, was down-regulated in SLE patients compared with control

225 ZPR1 is down regulated in SMA patients.

226 ArgBP2 is known to be down-regulated in some aggressively metastatic cancer

227 ch was highly expressed in CCA human tumors, was down-regulated in SOX17-transduced CCA cells.

228 Because IRS-1 is down-regulated in states of insulin resistance that o

229 many glycosylation sites on surface proteins were down-regulated in statin-treated cells compared to

230 on cross section serving PSII photochemistry was down-regulated in T. pseudonana through induction of

231 Th2) and T regulatory (Treg) differentiation were down-regulated in T cells stimulated in the presenc

232 We found that Gbx2 expression is down-regulated in Tbx1(+/-) embryos and is restored t

233 We report that hsa-miR-31-5p (miR-31) is down-regulated in TFH; we showed that BCL6 suppresses

234 f Runx2 and Osterix as well as Dlx5 and Msx2 were down-regulated in Tgfbr2-deleted cultures compared

235 us genes involved in gemcitabine sensitivity are down regulated in the resistant line upon CM03 treat

236 Finally, we demonstrate that Rheb levels are down-regulated in the AD brain, which is consistent

237 are up-regulated and downstream SRF targets are down-regulated in the hearts of MCKCUG-BP1 mice, whi

238 tiple DNA repair pathways have been shown to be down-regulated in the tumor microenvironment, whereas

239 Subsequently, stat92E activity is down regulated in the notum and distal pouch.

240 yoD, a master regulator of myogenesis, which is down-regulated in the absence of MASTR and MRTF-A.

241 n to mediate leanness and linked to obesity, is down-regulated in the absence of TDP-43.

242 Lrrn1 is down-regulated in the anterior hindbrain by the organ

243 hannel tetramerization domain containing 12, is down-regulated in the CSC-like cells of CRC.

244 the most widely characterized family member, is down-regulated in the depressed brain and plays a pro

245 in 3 (Ucn3), a marker for mature beta cells, is down-regulated in the early stages of T2D in mice and

246 we report that miR-24 (miRNA-24) expression is down-regulated in the ischemic border zone of the mur

247 transforming growth factor-beta1 expression is down-regulated in the Lamc3(-/-) retina, and SMAD sig

248 some studies have demonstrated that miR-27b is down-regulated in the oral specimens of patients suff

249 es with a QTL for rice blast resistance, and is down-regulated in the ospal4 mutant line; this may ex

250 an endothelial-specific, proangiogenic miR, is down-regulated in the peripheral muscles of patients

251 rticoid regulated kinase 1 (SGK1) expression is down-regulated in the postmortem PFC of PTSD subjects

252 angiogenic protein, thrombospondin-1 (TSP-1) is down-regulated in the prostate and liver of U19/EAF2

253 s critical for retinal progenitor expansion, is down-regulated in the triallelic mutant mouse.

254 Interestingly, secondary to this bmp4 is down-regulated in the Xenopus eyes.

255 miR-188-5p expression was down-regulated in the brain tissues from AD patients

256 The BMP pathway was down-regulated in the colons of human progastrin mic

257 Further, c-Fos was down-regulated in the hippocampus, together with a r

258 ation found that BMP/Smad4 signaling pathway was down-regulated in the K14-cre;Bmp2(f/f);Bmp4(f/f)ame

259 Megalin mRNA was down-regulated in the KO embryonic spinal cord (SC)

260 COPZ2 (but not COPZ1) was down-regulated in the majority of tumor cell lines a

261 The expression of miRNA-193b-3p was down-regulated in the mouse spleen and liver and in

262 We found that miR-663 was down-regulated in the mtDNA-depleted Rho(0) line.

263 xpression of multiple enamel matrix proteins was down-regulated in the mutant ameloblasts, the cleava

264 ately 2 Mb mapping interval whose expression was down-regulated in the mutant pool was subsequently d

265 rs (VCDs) and thickened choroids, while BMP2 was down-regulated in the RPE from eyes wearing -10 D le

266 EHD2 expression itself was down-regulated in the visceral fat of two obese mous

267 s were up-regulated whereas 36% of LPE genes were down-regulated in the absence of this receptor.

268 ways related to proliferation and cell cycle were down-regulated in the confluent cells.

269 Interestingly, these mitochondrial proteins were down-regulated in the CTX model thereby linking oxi

270 paraoxonase 2 and glutathione peroxidase 3, were down-regulated in the eye angle tissue of 18-month-

271 ins were differentially up-regulated and 400 were down-regulated in the fast muscle compared with slo

272 0.75, respectively; P < 0.05); both pathways were down-regulated in the greatest-ADG compared with le

273 script as well as protein levels, while they were down-regulated in the GSH-depleted phytoalexin defi

274 Specifically, let-7d, miR-210, and -221 were down-regulated in the in situ and up-regulated in t

275 etylase sirtuin 1, a ChREBP-negative target, were down-regulated in the liver of alcohol-fed mice, th

276 f the beta cell transcriptional network that were down-regulated in the Nkx2.2(KO) mice, were maintai

277 three of these genes, Zic1, Hnf1b and Foxd3, were down-regulated in the posterior hindbrain, where ca

278 In contrast, inflammation-related genes were down-regulated in the RV and while oxidative phosph

279 n and its interaction partner, NHERF2, which were down-regulated in the streptozotocin group.

280 le control and 9 genes involved in apoptosis were down-regulated in the treatment tumor tissues versu

281 Several antioxidant genes were down-regulated in the Y437H mutant myocilin cell li

282 cS), and enzymes of chlorophyll biosynthesis were down-regulated in the yellow leaf tissue.

283 17p and normal karyotype, and that miR-181b was down-regulated in therapy-refractory cases.

284 and "ts-53," respectively), ts-46, and ts-47 are down-regulated in these malignancies.

285 of anti-invasive microRNA200a (miR200a) that is down-regulated in TNBC.

286 homolog of the rice NAC domain gene AsNAC60 were down-regulated in transgenic plants.

287 Among those, miR-24, miR-145, and miR-210 were down-regulated in Tregs compared with controls and

288 D(+)-dependent deacetylase Sirtuin 1 (SIRT1) is down-regulated in triple-negative breast cancer.

289 In contrast, the ASncmtRNAs are down-regulated in tumor cells regardless of tissue o

290 ntitative RT-PCR: 14 were up-regulated and 4 were down-regulated in tumors with a higher Gleason scor

291 Dnmt3b was down-regulated in tx-j mice together with global DNA

292 numerous extracellular virulence genes that are down-regulated in USA300DeltasaeR/S.

293 ult to reconcile observations that profilin1 is down-regulated in various invasive adenocarcinomas an

294 th cells in which iPLA(2)beta expression had been down-regulated in vitro.

295 r partial hepatectomy, we found that DN-DBC1 is down-regulated in vivo during regeneration.

296 e expression of synapsin genes SYN1 and SYN2 was down-regulated in vivo and in vitro by alphaSyn olig

297 rate xenografts in which EGFRvIII expression was down-regulated in vivo, uPAR assumed a major role in

298 sis and fatty acid biosynthesis; these genes were down-regulated in wild-type or WRI1-overexpressing

299 t time that NCX1 mRNA and protein expression was down-regulated in Wilms tumor and RCC.

300 %) of S-palmitoylation sites on 254 proteins were down-regulated in Zdhhc13-deficient mice, represent