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1 the recombination of IgH gene segments that are flanked by 23-nt spacer recombination signal sequenc
3 tains a domain of 11 zinc finger motifs that is flanked by 267 amino acids on the N-terminal side and
7 in the abasic site when the fluorescent base is flanked by 5'- and 3'-thymines than in the context of
10 the 12 Maque elements found in the database were flanked by 9-14 bp direct repeats, indicating that
12 five-residue cystine-linked cyclic peptides are flanked by a C-terminal methyl ester and a 12-oxo- o
13 artite structure such that the hrp/hrc genes are flanked by a conserved effector locus and an exchang
14 majority of these 21-mer clusters (705/831) are flanked by a degenerate 22-nt motif that is offset b
15 aled that both ends of the ser2 gene cluster are flanked by a novel insertion sequence (IS1601) orien
17 duplications in the D. pseudoobscura genome are flanked by a repetitive sequence also found at the b
18 have normal incisors which, in the maxilla, are flanked by a supernumerary pair of incisor-like teet
19 ed genic regions, Pol IV-transcribed regions are flanked by A/T-rich sequences depleted in nucleosome
20 tance, probably because the promoter may not be flanked by a strongly positioned nucleosome on the up
22 s composed of six exons and five introns and is flanked by a 1.2-kb 5' promoter and a 1.2-kb 3' termi
26 I (Rsp) gene cluster in P. fluorescens SBW25 is flanked by a homologue of the P. syringae TTSS-secret
27 ly showed that the CtBP-binding motif in E1A is flanked by a Lys residue and suggested that acetylati
29 to the chromosome at the dif site (difA) and is flanked by a partial repeat of the dif site (difB).
31 AAV serotypes 1 through 6, the nicking site is flanked by a sequence that is predicted to form a ste
33 us cereus PI-PLC, the rim of the active site is flanked by a short helix B and a loop that show an un
34 1,2,4-trioxolane (3) in which the trioxolane is flanked by a spiroadamantane and spirocyclohexane was
36 luster is conserved in all three strains and is flanked by a unique exchangeable effector locus (EEL)
38 n addition, 14 of the 19 proviruses analyzed were flanked by a 6-bp direct repeat of host sequences,
39 rate that phosphorylation of Ser-1106, which is flanked by acidic amino acids, is regulated in vivo b
40 FP) expression, whereby the LCR-GFP cassette is flanked by adeno-associated virus (AAV) inverted term
42 However, the mouse and rat AR FXXLF motif is flanked by Ala(33) that evolved to Val(33) in primate
43 brane targeting (Lys-19, Lys-22, and Lys-25) are flanked by an exposed N-terminal helix (residues 26-
45 tudies suggested that S-nitrosylated Cys may be flanked by an acid-base motif or hydrophobic areas an
48 , the RDEC-1 LEE is not inserted at selC and is flanked by an IS2 element and the lifA toxin gene.
49 ch a nucleotidyltransferase catalytic domain is flanked by an upstream NMN-binding module and by down
50 two TCRbeta locus (Tcrb) D segments, Dbeta1 is flanked by an upstream promoter that directs its tran
52 sitioned on the 3'-side of a T or a U, which is flanked by an upstream T or U suggesting that a T/U p
56 The deletion spans approximately 500-kb and is flanked by approximately 147-kb segmental duplication
57 segments of integral membrane proteins often are flanked by aromatic or charged amino acid residues,
59 rcent of all nodes of Ranvier in this region were flanked by at least one paranode generated from an
62 cloned in a eukaryotic expression vector and is flanked by bacteriophage promoters for in vitro trans
63 histidine residues, with most of these sites being flanked by basic amino acid residues, and predicte
64 e ataxin-7 repeat and translation start site are flanked by binding sites for CTCF, a highly conserve
68 -based biosensor in which full-length CaMKII is flanked by CFP and YFP, to measure CaMKII activation
77 protein contains 11 leucine-rich repeats and is flanked by cysteine rich regions, which identifies it
78 to determine that the k10 critical interval was flanked by D10Mit10 and D10Mit162/D10Mit122 and cose
80 m a second crystal structure in which ddFLN5 is flanked by ddFLN4 and ddFLN6 at both N- and C-termini
82 however, in the context of Golli-MBP, Ac1-9 is flanked by determinants which prevent its display to
85 domain, range in size from 81 to 107 bp, and are flanked by direct repeats that vary in length from 6
88 y on the low-copy F'(128) plasmid, where lac is flanked by direct repeats of the transposable element
89 that integrates at a tRNA-methionine locus, is flanked by direct repeats, and encodes a P4-like inte
90 The aadA gene is the blocking sequence, and is flanked by directly oriented loxP sites for excision
91 te has a relatively open access channel that is flanked by disordered loops that may explain the rela
96 he second intron of E(beta) and show that it is flanked by DNA which is almost completely recombinati
101 is presented whereby split intein sequences are flanked by endoplasmic reticulum retention/retrieval
103 in congenic mice in which the targeted gene is flanked by ESC-derived passenger DNA potentially cont
104 he nucleoporin RanBP2 at a binding site that is flanked by FG-repeats and Ran-binding domains, and ov
105 eIF1A wherein a core ribosome-binding domain is flanked by flexible segments that mediate interaction
106 However, because the silencing GFP transgene is flanked by FLP recombination target (FRT) sites, we s
111 transfer to IdoUAalpha1,3GalNAcbeta1,4 that is flanked by GlcUAbeta1,3GalNAcbeta1,4 as compared with
112 urther hypothesized that the conductive pore is flanked by Glu-90 and located between helices A, B, C
117 tructure reveals a large central cavity that is flanked by His129 and Glu106, two residues that are w
120 ted central portion of each growth plate and were flanked by immature collagen II-expressing chondroc
121 ppears to have been laterally acquired as it is flanked by insertion element-like sequences and has a
122 nce analysis demonstrated that the RTX locus is flanked by insertion elements and has a reduced G+C c
125 U(L)) and unique short (U(S)) segments which are flanked by internal repeat (IR) and terminal repeat
126 n (TMD) of KCNE1 is a curved alpha-helix and is flanked by intra- and extracellular domains comprised
127 st, heterochromatin at centromeres I and III is flanked by inverted repeats termed IRCs, which are re
129 Ps but one group B LSP and five group C LSPs were flanked by IS6110 sequences in the references strai
130 oriented stimulus can be suppressed when it is flanked by iso-oriented versus orthogonally oriented
132 n syndromes, the rearranged genomic segments are flanked by large (usually >10 kb), highly homologous
134 ivation protein gamma (YWHAG) genes and that is flanked by large complex low-copy repeats, we identif
136 patients with dup(17)(p11.2p11.2) syndrome, is flanked by large, complex low-copy repeats (LCRs), te
138 er, in rice and in sorghum, mudrA-like genes are flanked by long terminal inverted repeats, as well a
139 e integrated DNA encoding the viral proteins is flanked by long terminal repeat (LTR) regions from th
141 Our data show that the active site of binase is flanked by loops that are flexible at the 300-micros
143 itional null mice by mating mice where grem1 was flanked by lox(P) sequences with mice expressing the
144 tch1/2 conditional mice, where Notch alleles are flanked by loxP sequences, with transgenics expressi
148 part of the first exon of the Lrat gene has been flanked by loxP sites, was generated and used in th
149 ourth exon of the alpha7 nAChR gene (Chrna7) is flanked by loxP sites (B6-Chrna7(LBDEx4007Ehs)) which
153 o, we generated a virus in which the M2 gene was flanked by loxP sites (M2.loxP), enabling the use of
154 gene essential for GSH synthesis, so that it was flanked by loxP sites and used the albumin-cyclizati
157 pes simplex virus thymidine kinase (HSV-tk), were flanked by loxP sequences so that they could be exc
160 Strikingly, many of these cellular genes are flanked by MERVL sequences or have cryptic LTRs as p
171 ivities, the AUG codon nearest to its 5' end is flanked by nucleotides that are incompatible with tra
174 g 3' overhangs, and it unwinds duplexes that are flanked by only a few nucleotides, as in the folded
175 y copy-number-variable DEFA1 and DEFA3 genes are flanked by other defensin genes present uniformly at
176 akpoints showed that 11 predicted inversions are flanked by pairs of highly homologous repeats in the
177 cifically, the MS haplotype region proved to be flanked by palindromic sequence stretches and by long
178 ch consists of two genes, gltA and gltB, and is flanked by palindromic sequences (51 and 44 nucleotid
181 so determination of the degree to which they are flanked by phased nucleosomes and subnucleosome-size
185 3a prefers CpG sites on a strand in which it is flanked by pyrimidines over CpG sites flanked by puri
189 e V, (D), and J gene segments, each of which is flanked by recombination signal (RS) sequences that a
192 coding sequences revealed that many of these are flanked by regions of elevated asymmetric CHH (where
197 other nucleic acid libraries where diversity is flanked by regions of relative sequence conservation,
198 ment of the extended 3' RR in mature B cells was flanked by regions associated with dimethylated K9 o
200 All endpoints of rearranged gene clusters are flanked by repeated sequences, tRNAs, or pseudogenes
206 t whose function remains largely unassigned, are flanked by sequences predicted to be poorly methylat
207 xons, located on three separate transcripts, are flanked by sequences that fold to form the conserved
208 5'-untranslated exon for opossum IGF2, which is flanked by sequences defining a putative neonatal pro
209 center 2 (IC2) on mouse distal chromosome 7 is flanked by several paternally repressed genes, with t
210 85% of mtDNA deletions identified in humans are flanked by short directly repeated sequences; howeve
212 that some sequences, before these deletions, were flanked by short direct repeats, a unique signature
213 genes revealed that random monoallelic genes were flanked by significantly higher densities of LINE-1
215 , we show that a double cut HDR donor, which is flanked by single guide RNA (sgRNA)-PAM sequences and
216 t a rapid phosphodiester bond formation step is flanked by slow conformational changes for both corre
217 s showed higher DNase I hypersensitivity and are flanked by strongly phased nucleosomes, consistent w
218 e expression variability, and their promoter is flanked by strongly positioned nucleosomes and tends
221 is 3000 parts per trillion (ppt); this peak is flanked by tails with Ir concentrations of 20 to 80 p
225 d adeno-associated virus type 2 (AAV) genome is flanked by terminal repeats (TRs) that fold back on t
228 T helper (Th) 2 and Th1 cells, respectively, are flanked by the equivalently expressed RAD50 and KIF3
231 plified using sequence-specific primers that are flanked by the requisite target sites for cloning, a
232 coding sequence of green fluorescent protein is flanked by the 5' and 3' untranslated regions from CA
234 copies of AF8; each peptide-encoding region is flanked by the appropriate dibasic or monobasic cleav
235 18q21, LCR 2, includes the D18S51 locus and is flanked by the D18S1109 and D18S68 loci, which are se
236 y (IE) ICP4 and ICP22/47 promoters, and oriL is flanked by the early (E) UL29 and UL30 promoters.
239 segment that includes the D18S858 locus and is flanked by the microsatellite loci D18S41 and D18S381
241 sule (cps) locus of Streptococcus pneumoniae is flanked by the pbp2x and pbp1a genes, coding for peni
243 The suppression channel runs parallel to and is flanked by the two aforementioned electrode channels
245 inactivated by serial synonymous mutations, was flanked by the NA segment-specific packaging sequenc
246 The ATP-binding pockets of the four paralogs are flanked by three side pockets, termed sites 1, 2, an
247 helix at one edge, whereas the opposite edge is flanked by three loops and the beta4 and beta7 strand
248 e moiety in which a chiral cyclopropyl group is flanked by triene and enal chromophores, and hence wo
249 bility group (HMG) transcription-factor gene is flanked by triose-phosphate transporter (TPT) and RNA
250 he high-abundance receptors Tar and Tsr, TM2 is flanked by tryptophan residues, which should localize
251 mprising three tetratricopeptide motifs that are flanked by two alpha-helical bundles and covered by
253 Interestingly, the AbiR genetic determinants are flanked by two IS982 elements generating a likely tr
254 Three genes implicated in MMF biosynthesis are flanked by two regulatory genes, which are related t
256 entral cyclobutane beta- or gamma-amino acid being flanked by two d- or l-proline residues, have been
257 onserved ATPase-dependent helicase core that is flanked by two alpha-beta-beta-beta-alpha double-stra
262 ssemble on a Cas2 domain dimeric core, which is flanked by two Cas3 domains forming a groove where th
263 halanilic acid (2CPA), where the amide group is flanked by two catalytic carboxyls, reveals key mecha
264 Furthermore, this critical region of EC2 is flanked by two conserved cysteine residues that are e
268 of a negative selectable marker, codA, which is flanked by two directly oriented lox sites (>codA>).
273 sequence 5'-CGA where the damaged nucleobase is flanked by two high-affinity intercalation sites of A
278 In the design template, a duplicated helix is flanked by two loop regions of different stabilities.
279 oexpressing OCT4, SOX2, KLF4 and c-MYC; this is flanked by two loxP sites in its long terminal repeat
281 le hexamers at the double hexamer interface, is flanked by two pairs of gate-forming subunits, MCM2 a
283 d by a highly fluorescent squaraine dye that is flanked by two polyethylene glycol (PEG) chains with
284 symmetry) such that the intercalator cavity is flanked by two sets of G x C base pairs (i.e., C5 x G
286 ately 450 kilobases containing 26 exons that are flanked by typical splice donor and acceptor sequenc
287 nge' implicated in K(+) channel opening, and is flanked by tyrosine 652 and phenylalanine 656, which
288 variants and identify that 11 million or 57% are flanked by uHs, covering 88% of protein-coding genes
292 meric expression sites (ESs) where VSG genes are flanked by upstream 70 bp repeats and downstream tel
293 ric bacteriophage Mu, the BcepMu genomic DNA is flanked by variable host sequences, a result of trans
295 at shares the alpha-crystallin domain, which is flanked by variable, disordered N- and C-terminal ext
299 cin B phosphotransferase-encoding gene (hpt) was flanked by ZFN recognition sequences was constructed
300 orescent protein (GFP) coding sequence (gfp) was flanked by ZFN recognition sequences was used to pro