ライフサイエンスコーパス: be important for

1 tle attention to the gross components, which are important for a number of reasons, including underst

2 Perception of visual motion is important for a range of ethological behaviors in mam

3 and understanding their fleet apportionment is important for a successful air pollution policy.

4 tosis undergo characteristic rounding, which is important for accurate spindle positioning and chromo

5 Even though autophosphorylation is important for activation, its role remains elusive in

6 The position and identity of the sugar group is important for activity, as is the position of a numbe

7 trinsic cysteine, and not lysine, reactivity was important for activity against HCMV.

8 a plant's realized environmental niche, and is important for adaptation to climate.

9 studies and conservation applications, which are important for adaptive management.

10 surface of the ADAR1 deaminase domain which is important for ADAR1 editing activity.

11 Even though mTOR/protein kinase B signaling is important for adipogenesis, the role of regulated dev

12 RNPH and HNRNPK with the treatment appear to be important for antiviral activity.

13 orld, and the type I interferon (IFN) system is important for antiviral control in the brain.

14 results in reliable growth predictions that are important for assessing individual growth, populatio

15 ted Inp1 variants showed that the C terminus is important for association to the peroxisome, while a

16 e data suggest that nuclear localization may be important for AtDRO1 function and suggests a more nua

17 unctional integration of the default network is important for autobiographical episodic memory perfor

18 itutes recently discovered K(+)channels that are important for autophagosome turnover and lysosomal p

19 g-distance trafficking of palmitoyl-proteins is important for axon integrity and for axon-to-soma ret

20 via the Gp130/JAK/STAT3 and DLK/JNK pathways are important for axonal injury responses, and we found

21 causal tissues of human traits and diseases is important for better interpreting trait-associated ge

22 s in mouse TNBC cells revealed proteins that are important for both cilia and BC biology.

23 gulation of enhancer function, and that HICE are important for both signal integration and compartmen

24 eper within the dorsal horn (laminae III-IV) are important for both types of injuries.

25 dentified the cytoskeletal protein KHARON as being important for both flagellar trafficking of the gl

26 a key role in heme biology in T. gondii and is important for both mitochondrial and general parasite

27 Although vision is important for calibrating auditory spatial perception

28 pment of approaches to induce clearance will be important for cancer prevention and the treatment of

29 s its association with cofilin and actin and is important for CAP1 to regulate the actin cytoskeleton

30 n the treatment of systemic hypertension, it is important for cardiologists, general practitioners an

31 usions that extend from the cell surface and are important for cell-cell communication and pathogen i

32 found that two central, consecutive prolines are important for cell-cell fusion and pathogenesis.

33 e alterations in D-loop properties appear to be important for cell survival and mating-type switch in

34 lycosylation of the Fc region of alpha-GA(1) is important for cell entry and efficacy.

35 tenance of a cell type-specific cell density is important for cell function.

36 mammalian) target of rapamycin (mTOR) kinase is important for cell survival and proliferation, and vi

37 Nuclear pore complexes (NPCs) are important for cellular functions beyond nucleocytopl

38 nd biophysical properties of lipid membranes are important for cellular functions in health and disea

39 droplets that are increasingly understood to be important for cellular function.

40 of both glycerolipids and sphingolipids and is important for cellular expansion during vegetative gr

41 Th17 cells secrete IL-17A and are important for clearing extracellular pathogens, but

42 An accurate rotavirus diagnosis is important for clinical management and monitoring acti

43 Prediction of surgical risk preoperatively is important for clinical shared decision-making and pla

44 Yet, knowledge of disease incidence is important for clinicians and researchers to guide hea

45 Parvalbumin (PV)-expressing interneurons are important for cognitive and emotional behaviors.

46 Such speed is important for compound library, assay and future clin

47 ildlife abundances over broad spatial scales is important for conservation.

48 Primary and secondary prevention measures are important for controlling these malignancies-most im

49 V reactivation.IMPORTANCE Type I interferons are important for controlling virus infection.

50 ng healthcare-resource utilization data will be important for cost-effectiveness evaluations of RSV i

51 The phosphoprotein osteopontin is important for critical physiological processes, inclu

52 cestral hosts for BTV but are less likely to be important for cross-species transmission, sheep and c

53 Here we show that the sliding clamp PCNA is important for crossover-biased resolution.

54 rstanding HIV dynamics across the human body is important for cure efforts.

55 accepted that the orbitofrontal cortex (OFC) is important for decision-making.

56 tern and levels of expression of these genes is important for deeper understanding of SARS-CoV-2 trop

57 Characterizing network features can be important for designing and evaluating health program

58 Understanding this changing circuitry is important for designing targeted therapies.

59 tion of the effective reproductive number Rt is important for detecting changes in disease transmissi

60 Vegetation-fire feedbacks are important for determining the distribution of forest

61 Average pO2 is important for determining if a transplant site and ca

62 ific characteristics of resistance mutations is important for determining potential subsequent treatm

63 t proteins of small-molecule drug candidates is important for determining their molecular mechanisms

64 The findings of this paper are important for development of stable and robust syste

65 Although apoptosis is important for development, attenuation of apoptosis c

66 that psychological intervention programs may be important for diabetes management, beyond current pro

67 latex monodisperse polystyrene (PS) colloids are important for different advanced applications (e.g.

68 KDM6A is important for differentiation of embryonic stem cells

69 ophilic transinteraction between Dsg and Dsc is important for disease pathology in both pemphigus fol

70 ecture of traits that have been suggested to be important for divergence.

71 The ATR system is important for E. coli survival in the mouse intestine

72 s expressed in latently infected B cells and is important for efficient EBV-induced transformation of

73 TSG101 binding is important for efficient HIV-1 release, but how ESCRTs

74 HIV-1 Vpr, a protein carried in the virion, is important for efficient infection of primary macropha

75 hydrophobic pollutants generated by industry is important for environmental and human health.

76 representing spatial landmarks, which could be important for error correction during path integratio

77 l, endocytosis, and signal transduction that is important for ESC proliferation and differentiation.

78 Virtual care is important for expanding access to health services, bu

79 This framework will be important for explaining patterns of extant floral di

80 an Ala306-Phe307-Arg308 motif of human ALAD are important for [Fe(4)S(4)] cluster acquisition and co

81 RhoA signaling and downstream pathways that are important for full profibrotic myofibroblast functio

82 hat AHR up-regulates sphingolipid levels and is important for full axon myelination, which requires e

83 inhomogeneities of interfacial environments are important for fully characterizing the solvation of

84 Sizes of intracellular structures are important for function, yet mechanisms underlying su

85 ps, including highly conserved Trps that may be important for function, protein-lipid interactions, a

86 t with the possibility that the microtubules are important for furrow formation.

87 for strain lineage determination, which may be important for future studies in associating precise M

88 undamental aspect of metallobiochemistry and is important for gaining insights into bacterial growth

89 promote or inhibit origin activation, which is important for genome maintenance.

90 Therefore, stored mRNAs are postulated to be important for germination.

91 s glucosyltransferase (GtfB) activity, which is important for glucan matrix development and GtfB-medi

92 High RanGTP around chromatin is important for governing spindle assembly during meios

93 monly-used methods in cluster identification is important for guiding clustering-triggered interventi

94 g the dependency of fisheries on coral reefs is important for guiding fishery responses to coral reef

95 These residues are important for H(+) transport and voltage-dependent g

96 ons have shown that the timing of eating may be important for health-related outcomes.

97 ing the fluctuations in blood glucose levels is important for healthy subjects and crucial diabetic p

98 It is important for hematopoietic differentiation and plays

99 ondition-demographic responses may therefore be important for herbivore population dynamics in fluctu

100 This turns out to be important for hESC pluripotency.

101 found that the KSHV gH (ELEFN(50-54)) motif is important for higher KSHV fusion and that EBV gH/gL d

102 However, we also find that RNF8 is important for homology-directed repair (HDR) independ

103 These data suggest contact precautions are important for hospital VRE control programs.

104 Inflammasomes are important for host defence against pathogens and hom

105 gain-of-function assays indicated that GBP2 is important for IFN-gamma-dependent anti-MNV activity i

106 Taken together, HSP70 chaperone is important for IKKepsilon activation, and MERS-CoV ORF

107 Mucosal-associated invariant T (MAIT) cells are important for immune responses against microbial inf

108 is of apoptotic cells via the receptor MerTK is important for immune tolerance.

109 The control of gene expression noise is important for improving drug treatment and the perfor

110 r than RIS-dependent sleep bouts, appears to be important for increasing survival after cellular stre

111 The BumSR TCS, which is important for infection of humans and optimal coloniz

112 ind that AMPK-mediated glycolytic activation is important for infection, as overexpression of GLUT4,

113 ctor (TF) binding influences gene expression is important for inferring target genes from TF chromati

114 Platelet-neutrophil interactions are important for innate immunity, but also contribute t

115 Facial expressions are important for intentional display of emotions in soc

116 hemical signature of femoral pore secretions is important for intra- and inter-specific chemical comm

117 lipid oxidation promoted by hemoglobin (Hb) is important for its applications in muscle foods.

118 esponse to stimulation and such modification is important for its dynamic localization and function i

119 ted by host kinases, and its phosphorylation is important for its function.

120 ed in the first receptor-binding domain that is important for its stability, and the second receptor-

121 ity, but not nuclear localization of SAMHD1, is important for its suppression of innate immune respon

122 The epsilon structure of HBV RNA was important for its antiviral activity and cleaved by

123 demonstrate that the F2PH and F3 subdomains are important for kindlin self-association.

124 IGNIFICANCE STATEMENT The dentate gyrus (DG) is important for learning, memory, pattern separation, a

125 ide release, we hypothesized that I(h) would be important for LNvs communication.

126 This biomass production is likely to be important for local food webs, as a trophic subsidy t

127 nhibition, suggesting that efferent feedback is important for long-term maintenance of inner ear func

128 ear if exceptional polymer length of vHMM-HA is important for longevity.

129 Root-associated microbial communities are important for maintaining agricultural productivity.

130 fail to detect low-density parasitemias that are important for maintaining malaria transmission.

131 nsposon elements and is therefore thought to be important for maintaining germline cell fate.

132 rine model of sepsis, P2X7 receptor activity is important for maintaining elevated levels of CD14 in

133 Although cellular stress response is important for maintaining function and survival, over

134 pture experiments show that cohesin turnover is important for maintaining promoter-enhancer loops.

135 of the CNS; as professional phagocytes they are important for maintenance of the brain's physiology.

136 tructures and within the adipose stroma, and are important for mammary gland development and tissue h

137 Imaging differentiation is important for management and isolation purposes and f

138 Enzyme assays are important for many applications including clinical d

139 temporal fine structure of acoustic stimuli is important for many aspects of hearing.

140 ise regulation of integrin-mediated adhesion is important for many developmental migration events.

141 Continued program evaluation is important for measuring long-term population impact.

142 , and allows access to building blocks which are important for medicinal chemistry and drug discovery

143 erience-driven changes in oligodendrogenesis are important for memory consolidation.

144 human hippocampus and mPFC, two regions that are important for memory-guided behaviors, in two tasks:

145 during the 'active' theta state of the brain are important for memory-guided navigation and rely on v

146 pple events (SWRs), which have been shown to be important for memory consolidation.

147 AhR is important for modulation of the host immune response

148 Striatal dopamine D2 receptors (D2Rs) are important for motor output.

149 The basal ganglia are important for movement and reinforcement learning.

150 c binds to the promoter of the MTR4 gene and is important for MTR4 expression in HCC cells, indicatin

151 ution element-like 1 (NDEL1) enzyme activity is important for neuritogenesis, neuronal migration, and

152 later events in cortical development, which are important for neurodevelopmental disease modeling.

153 Our study suggests that primary cilia are important for neuronal maturation and function in ce

154 irected repair and nonhomologous end joining is important for neuronal cells.

155 the RAB21 and PIP5K1C90 polarization, which is important for neutrophil adhesion to endothelia durin

156 PM PtdIns4P direct RPH3A polarization, which is important for neutrophil firm adhesion to endothelia.

157 heterogeneity in infectiousness and contact are important for NoV outbreak prevention and control, y

158 Shared environmental factors were important for only some of these clusters and expla

159 It was recently shown that KIFC1 is important for organizing axonal microtubules in neuro

160 e of slip-pulse formation and structure that is important for our fundamental understanding of both e

161 hysiology during hydrocarbon degradation can be important for parameterizing models that predict the

162 tidine) elicit an immune response, which may be important for patient's responses to DNMTi.

163 Feedback inhibitory motifs are thought to be important for pattern separation across species.

164 a high-frequency bursting mode and that this is important for peptide transport and the control of be

165 These findings reveal that EutR not only is important for persistence during the primary host inf

166 ely, these data show that CeA-LH projections are important for persistent avoidance of stress-related

167 ic range to minimize bleeding and thrombosis is important for personalized treatment of NOACs.

168 uality and content of online information, it is important for physicians to be aware of the different

169 portions of beta- and gamma-ENaC subunits as being important for PIP(2)-ENaC interactions.

170 Delineation of catchments is important for planning emergency care delivery and in

171 nd a central pleckstrin homology-like domain are important for plasma membrane binding.

172 ur data support the model that TFIIB release is important for Pol II to successfully escape the promo

173 SgmX, in turn, is important for polar localization of the T4P extension

174 Among other functions, GPT1 was shown to be important for pollen and embryo-sac development.

175 Thus, Pol II elongation speed is important for poly(A) site selection and for regulati

176 relative to the active site also appeared to be important for polymer elongation.

177 Both sites are important for polymerase de novo initiation and elon

178 chanisms behind population changes therefore is important for population management, both locally and

179 This study demonstrates that neuronal NAMPT is important for pre-/post-synaptic NMJ function, and ma

180 ing of warming-induced morphological changes is important for predicting biotic responses to global c

181 res and local-scale environmental conditions is important for predicting metapopulation dynamics and

182 -drying microencapsulation together with DSC is important for preserving a high concentration of bioa

183 th sector in multisectoral approaches (MSAs) is important for prevention and control of chikungunya a

184 that considering the quality of plant foods is important for prevention of MetS in a population that

185 t the infralimbic prefrontal cortex (IL-PFC) is important for processing social information and, in s

186 junctional protein that stabilizes ECs, and are important for proper neuronal function.

187 ation-dependent manner, and this recruitment is important for proper chromosome congression.

188 mational flexibility of the two HEPN domains is important for proper nuclease function.

189 The induction of anti-CSP antibodies is important for protection, however, it is unclear how

190 sistent, coordinated and tailored approaches are important for providing appropriate care to all peop

191 Hospice programmes are important for providing end-of-life care to patients

192 , the catalytic activity of Pop2 deadenylase is important for Pumilio RD activity.

193 mutations rewire regulatory-protein networks is important for rationalizing the mechanisms of oncogen

194 ion, the facial and vocal tract regions that are important for reconstruction are those that are used

195 was used to identify which areas of the face were important for recovering information about the voca

196 the microenvironment of the overgrown tissue are important for recruiting macrophages.

197 Nowadays, energy-saving building materials are important for reducing indoor energy consumption by

198 uality health providers and birth attendants are important for reducing maternal mortality.

199 Although TFR2 in the liver has been shown to be important for regulating iron homeostasis in the body

200 that phosphotransfer activity of HPr and EI is important for regulation of atxA.

201 the removal of activating histone marks, and is important for remethylation of the locus.

202 These results demonstrate that FoxM1 is important for renal tubular regeneration following AK

203 The requirement for GBF1 implies that Arfs are important for replication, but which of the differen

204 f various read assembly programs in practice is important for researchers to choose which programs to

205 butyric acid catabolism, which were found to be important for resisting killing by H(2)O(2) Finally,

206 s widespread IFN-independent activities that are important for restricting HSV-1 infection, tumor imm

207 Although the timing and degree of uncoating are important for reverse transcription and integration,

208 he nucleus accumbens shell (an area known to be important for reward and motivation) in the augmentat

209 tion, which has previously been predicted to be important for Rheb-signalling suppression.

210 for primary Gi/o-coupling; however, it might be important for secondary Gi/o-coupling.

211 e-tune root and root hair development, which are important for seedling establishment at the beginnin

212 y has revealed that some higher visual areas are important for seeing even simple visual features, wh

213 Here we demonstrate that Nef homodimers are important for SERINC5 down-regulation, trafficking t

214 ltimately show that species interactions can be important for setting upslope range margins.

215 o an oxidative stress tolerance network that is important for single cells during glandular developme

216 city within microdissected brain nuclei that are important for social behaviors.

217 ding and twisting deformations-features that are important for soft device applications.

218 temporal gyrus (pSTG), a brain area known to be important for speech perception.

219 environment of mammalian reproductive tract are important for spermatozoa swimming behavior and play

220 d the so-called NineTeen complex (NTC) which is important for spliceosomal activation.

221 is study suggests that M-current suppression is important for stable encoding of specific types of me

222 PET is important for staging and prognostication with stage

223 Our results are important for studies in fluid dynamics, remote sens

224 ishing lung lymphatic drainage is thought to be important for successful lung transplantation.

225 rly innate signaling and Th1-skewed immunity are important for survival.

226 variability in ACE2 expression levels could be important for susceptibility to COVID-19 or its outco

227 While synaptic inhibition is important for synchronization across the gamma-freque

228 This protein is also thought to be important for T. gondii-host interaction, pathogenesi

229 reliable identification of at-risk patients is important for targeted implementation of renal protec

230 improving, and outcomes beyond mortality may be important for testing new treatments.

231 tion, and both light and the cobalt catalyst are important for the dehydrogenation step.

232 cis-acting elements in the HIV-2 genome that are important for the encapsidation of full-length RNA i

233 Our findings are important for the improvement of CAR-T cell-based im

234 mmox (anaerobic ammonium oxidation) bacteria are important for the nitrogen cycle in both natural env

235 eural circuits within the brain regions that are important for the regulation of cardiac vagal tone a

236 ly, loss of BglP and BglB suggests that they are important for the regulation of virulence-related ge

237 s in the absence of stress suggest that they are important for the symbiosis.

238 ellular vesicles (EV) has been postulated to be important for the activity of EV-carried miRNA in mod

239 gregation and spreading of aSyn and tau will be important for the development of future therapeutic i

240 ch other's folding in distinct ways that may be important for the efficient assembly of alpha-spectri

241 Leu(137) of HY5 is found to be important for the HY5-BIN2 interaction and HY5-mediat

242 n metabolism of P. aeruginosa is believed to be important for the pathogenicity of this bacterium in

243 s transmission, sheep and cattle continue to be important for the transmission and maintenance of inf

244 They are recognized as being important for the development of invasive MRSA inf

245 Taken together, we identified CAMSAP3 as being important for the formation of central MT pairs, p

246 sphoglycerate mutase family member 5 (PGAM5) is important for the antiviral cellular response.

247 Analysis of particulate matter (PM) is important for the assessment of human exposures to po

248 erpolarization-activated cation current I(h) is important for the behaviors that the LNvs influence:

249 A quantitative model of such behavior is important for the better understanding of the functio

250 The NF-kappaB family of proteins is important for the cell to mediate this response.

251 y differ depending on the biological context is important for the development of flu treatments.

252 otective immunity in the FRT, a finding that is important for the development of p.o. subunit vaccine

253 sses are affected by mechanical forces in TE is important for the development of skin treatments to m

254 lating tumor cells (CTCs) in patients' blood is important for the diagnosis and monitoring of cancer.

255 Developmental synaptic remodeling is important for the formation of precise neural circuit

256 The putative priming loop that is important for the initiation of RNA synthesis is full

257 iant should not be tested in isolation; this is important for the large majority of the 100 million i

258 ules and enriched in B and Foxp3(+) T cells, is important for the maintenance of allograft tolerance.

259 the cytosol and nucleus in the cells, which is important for the maintenance of different equilibriu

260 ated by iron regulatory protein 1 (IRP1) and is important for the maintenance of mitochondrial respir

261 egulation of protein kinase A (PKA) activity is important for the motile behavior of many cell types,

262 al and clinical evidence suggests that vIL-6 is important for the onset and/or progression of HHV-8-a

263 tion involving apical VNO receptors like V1R is important for the outcome of an initial social compet

264 conjugate nedd8 to VHL within a region that is important for the p53-VHL interaction.

265 These results show that the alpha2 subunit is important for the potentiation of GlyRs in the adult

266 underlying complex disease traits in humans is important for the progress of human disease genetics;

267 Moreover, TRAIP is important for the recruitment of NEIL3 but not FANCD2

268 In addition, we show that pUL47 is important for the splicing of UL44 transcripts encodi

269 eutic immune cells to recognize cancer cells is important for the success of cell-based cancer immuno

270 CCR6 is important for the trafficking of IL-17A-producing gam

271 hancing survival while production of insulin was important for the antidiabetic effect.

272 xicity (ADMET) properties of drug candidates are important for their efficacy and safety as therapeut

273 the major structural proteins (archaellins) is important for their subsequent incorporation into the

274 nescence is a candidate mechanism that might be important for this conversion.

275 hogen transport associated with microplastic is important for this industry.

276 and a DNA binding motif was identified that is important for this transcriptional repression.

277 expressed in thymocytes, and since migration is important for thymocyte maturation, we investigated a

278 OTCH2 activation, and O-fucosylation on EGF9 was important for trafficking of both NOTCH1 and NOTCH2.

279 Circadian modifications to histones are important for transcriptional initiation and feedbac

280 Chimeras (PROTACs) to degrade proteins that are important for tumorigenesis has emerged as a potenti

281 enesis approach and identified residues that are important for ubiquitin binding.

282 ce of broken symmetry in ordered systems and are important for understanding a wide variety of phenom

283 occupancy maps of transcriptional regulators are important for understanding gene regulation and its

284 rations in fine particulate matter (PM(2.5)) are important for understanding potential health impacts

285 rther present advances in animal models that are important for understanding the pathogenesis of SARS

286 These types of studies are important for understanding the potential effects of

287 of the new phases that we report here would be important for understanding dynamics, geochemical cyc

288 in the auditory periphery does not appear to be important for understanding the cortical representati

289 g different types of coevolutionary dynamics is important for understanding biodiversity and infectio

290 and warming water temperatures on salmonids is important for understanding how climate warming will

291 of mitochondrial electron transport enzymes is important for understanding mechanisms of metabolic d

292 ransmission and heterogeneous infectiousness is important for understanding NoV transmission dynamics

293 Their presence is important for understanding the health conditions, hy

294 brain structures among psychiatric disorders is important for understanding the pathophysiology.

295 that another key virulence regulator, ToxR, was important for V. cholerae resistance to hydrogen per

296 hus monitoring the virus in both seasons may be important for vaccine development.

297 c data and microhabitat characteristics that are important for vector reproduction are imperative to

298 rovides evidence that FMDV genetic diversity is important for viral virulence and transmissibility in

299 , forms a homopentameric cation channel that is important for virus pathogenicity.

300 everal other host factors have been found to be important for ZBP1-NLRP3 inflammasome assembly, inclu