ライフサイエンスコーパス: be located at

1 nce, and rs1441519 (P = 1.6 x 10(-6)), which is located at 11p14, potentially affecting nitric oxide

2 Because miR-3676 is located at 17p13, only 500-kb centromeric of tumor pr

3 e 2 (NOS2; P = 1.28 x 10(-9)), both of which are located at 17q11.2-q12, and rs8069176 near gasdermin

4 Both SNPs are located at 17q25, an interesting region that has bee

5 One peak is located at 20 degrees ~ 30 degrees N and the other ex

6 o, Ni, V, Cu, Cr, Mg, Zn, Fe, Al, Li, and Ti were located at 21-80 nm; and Se, Ca, and Si showed high

7 ingle placenta-specific LCR component, HSIV, is located at -30 kb to the cluster.

8 ribed developmental disorder (6p22 syndrome) is located at 6p22.

9 O levels: rs208515 (P = 3.3 x 10(-8)), which is located at 6q12, probably acting in "trans" and expla

10 The emission of the probe is located at 735 nm in the NIR region, which is favorab

11 nse 1 (CSR1) is a tumor suppressor gene that is located at 8p21, a region that is frequently deleted

12 uence analysis, we demonstrate that most SEs are located at a chromatin loop end and that most uterin

13 These are located at a convex surface of the NusA-NTD, situate

14 ust rely on communication between cells that are located at a distance from each other within the org

15 no acids cause haploinsufficiency for LOX or are located at a highly conserved LOX catalytic domain,

16 experimentally identified surface-bound ions are located at a potential that facilitates binding, whi

17 the effects of mutations of amino acids that are located at a proline kink in M1 that separates pi an

18 The results show the b dimer to be located at a non-catalytic alpha/beta cleft, with bI

19 Importantly, the glycine-leucine sequence is located at a conserved distance before the first tran

20 India is located at a critical geographic crossroads for under

21 ggests that the receptor-binding site for QX is located at a different location on the spike than tha

22 ith a mean diameter of about 950 kilometres, is located at a mean distance from the Sun of about 2.8

23 A third site is located at a pocket right below the agonist binding s

24 pproximately 80 base pair (bp) of DNA, which is located at a position that corresponds to the central

25 e ATPase family of membrane transporters and is located at a seemingly strategic position at the inte

26 electron microscopy demonstrated that E4 34K is located at a single site on the virus surface.

27 In addition, the Rho insert helix, which is located at a site remote from the PBD46 binding inter

28 ing complex called the portal protein, which is located at a unique 5-fold vertex.

29 p to the distorted left-handed PP(II) helix, is located at a unique position, as compared with the ph

30 he second group, the sterilization equipment was located at a central facility and the instruments we

31 and all castes, the largest glomerulus (G1) was located at a similar position relative to four ident

32 was part of an orfX toxin gene cluster that was located at a unique chromosomal site distant from th

33 Selected tissue anchors were located at a mean depth of 54.3 microm; the most co

34 phenylphenalenones in which the phenyl ring is located at all possible peripheral positions of the p

35 ein, or connector, plus the terminase, which are located at an especial prohead vertex.

36 The site is located at an elevation of ~3,900 m above sea level a

37 One prominent target of LED was located at an enhancer region within CDKN1A gene, a

38 ix nonhydrolyzable GTPgammaS analogues) that are located at and stabilize the intersubunit interfaces

39 In general, the walls and ground may be located at any distance from, and at any orientation

40 n complex through a single S-domain that can be located at any position within an HS chain.

41 CB1 cannabinoid receptors (CB1) are located at axon terminals and effectively control sy

42 and a small population of macrophages, which were located at branch points.

43 oposed reaction mechanism at the MPW1K level was located at C1-O(Ser) = 1.92 A and C1-O1 = 3.11 A.

44 ibute to a noncanonical kinase activity, but was located at chromatin together with components of the

45 e patients, FA nuclease 1 (FAN1), whose gene is located at chromosome 15q13.3, is recruited to stalle

46 A striking association peak was located at chromosome 2q37.1 for both total bilirubi

47 nsors and Biochips (C3B(R)) has subsequently been located at Clemson University and at Texas A&M Univ

48 pth) gold-bearing rocks of Archaean age have been located at depths of 9,500 to 11,000 m.

49 rrying the chemotherapeutic drug doxorubicin are located at destroyed vascular locations, releasing t

50 hing points of electron and hole pockets and are located at different binding energies above EF.

51 fferential image motion between objects that are located at different distances from the observer's p

52 nd that the Weyl nodes with opposite charges are located at different energies due to the absence of

53 These IRESs are located at different relative positions between a co

54 rm in all of the synthesized haptens, but it was located at different positions of the parent molecul

55 iod, the plasmasphere had three bulges which were located at different geomagnetic longitudes.

56 ina, Winneba, Apam and Mumford respectively, were located at distances of less than one metre from th

57 rns across time, geography and subclade, and were located at distinct locations across the chromosome

58 In Trim5alpha, the B-boxes are located at either end of the coiled-coil, held in pl

59 e membrane, enabling the array of muITIES to be located at either the wider or narrower pore mouth.

60 A comparable number of NF-Y sites are located at enhancers, many of which are tissue speci

61 We found that neuroligin-1 (NL1), which is located at excitatory postsynaptic densities, regulat

62 of the final RNA primer, which is thought to be located at extreme chromosome ends.

63 s contained only 1 or 2 genes, and 9 regions were located at gene deserts.

64 hat the counterion in Drosophila Rh1 may not be located at Glu-181 as in amphioxus, or at Glu-113 as

65 ) of plasma membrane-associated m2 receptors were located at glutamatergic synapses.

66 PBPs are located at high concentrations (10(-4) M) between th

67 The results show that 32% of the case study is located at high and good suitability classes in the f

68 The variants were located at highly conserved residues in the FHF2A i

69 The mutation was located at homeodomain position 52Arg-->Gly (R52G).

70 pread across multiple domains, some of which are located at inhibitory contact sites formed with the

71 vels in endothelial and epithelial cells and is located at interendothelial junctions in confluent ce

72 ty suggests that the monitoring wells should be located at less than 1.2 km away from the injection w

73 icted in mitochondria but, surprisingly, six are located at lipid droplets in chloroplasts.

74 All epitopes identified were located at loops connecting the beta strands of MOG

75 all five metal-localized molecular orbitals are located at lower energy relative to the trifluoromet

76 ainshocks and their nearby early aftershocks are located at major subduction zones and continental bo

77 ssion yeast homologue of MOZART1, Mzt1/Tam4, is located at microtubule-organizing centers (MTOCs) and

78 Typically, these coupled residues are located at multiple distal sites and thus are predic

79 unoglobulin- or fibronectin-like domains and is located at nine sites, 43nm apart, in each half of th

80 ses of genome-wide association (GWA) studies are located at non-protein-coding regions.

81 ory effect disappear when the same reporters are located at nonallelic sites.

82 tium and UKB meta-analysis, 11 of 33 (33.3%) were located at novel SNPs, and 3 of 33 (9.1%) were nove

83 In Fv1Cyp, two CypA moieties are located at opposing ends, creating a molecule with a

84 terochromatic loci, HMLalpha and HMRa, which are located at opposite ends of the same chromosome-enco

85 conserved in all plant branching enzymes and are located at opposite openings of the 8-stranded paral

86 These regions are located at opposite sides of the protein allowing mu

87 Roughly half of a cell's proteins are located at or near the plasma membrane.

88 tic birds selected for alula optimization to be located at or near the lift-maximizing position predi

89 The binding site for CR1 was located at or near the MBL-associated serine proteas

90 ine-rich domain in maspin consists of 27 aa, is located at position 268-294, and is responsible for t

91 osphosites within structured domains tend to be located at positions with high conformational flexibi

92 ionarily conserved scaffolding proteins that are located at presynaptic active zones.

93 omerization; residues 289, 291, 324, and 328 were located at protruding subdomain 2 (P2) of VP1, whic

94 nlabeled cells occurred whether microlesions were located at rostral or caudal poles of HVC, indicati

95 reactive ends of the open-chain intermediate are located at short distances from each other with the

96 ucleosome-free regions (NFRs), many of which are located at sites occupied by the multivalent factors

97 Surprisingly, Fs(1)h-L is located at sites in the genome where multiple insulat

98 Nearly all the intimal dissection tears were located at sites of previous surgical trauma.

99 Most of the newly identified 3'UTR SNVs were located at sites that are complementary to seed seq

100 i were identified, of which 19 of 33 (57.6%) were located at SNPs previously identified by the GIANT

101 wo receptor-binding sites, which we now know are located at some distance from each other in IgE-Fc (

102 Such features are located at strategic positions for substrate recogni

103 residues, like those in the etomidate site, are located at subunit interfaces near the synaptic side

104 DNA damage foci in stress-induced senescence are located at telomeres irrespective of telomerase acti

105 ion, neighboring invariant Met, Asp, and Glu are located at the "entrance" of the ion path.

106 nanometric Ir clusters in MWW zeolite, which are located at the 10MR window connecting the two neighb

107 We show many are located at the AIS, interact with known AIS proteins

108 phatidylinositol-anchored proteins (GPI-APs) are located at the apical surface of epithelial cells.

109 voltage-gated K(+) channels Kv7.2 and Kv7.3 are located at the axon initial segment (AIS) and exert

110 y granules by routine histology, these cells are located at the base of the crypts of Lieberkuhn, tin

111 Microsporidia are located at the base of the fungal evolutionary tree.

112 Adult intestinal stem cells are located at the bottom of crypts of Lieberkuhn, where

113 ( approximately 10%) of total beta1 subunits are located at the cell surface.

114 , including mycobacteria, protein aggregates are located at the cellular pole.

115 d the six connecting {Mo(2)O(2)S(2)} linkers are located at the corners and at the edges, respectivel

116 ntestinal intraepithelial lymphocytes (IELs) are located at the critical interface between the intest

117 ately noncycling, long-lived stem cells that are located at the crypt base and that, upon injury, pro

118 py and proteomics revealed that the granules are located at the cytoplasmic site of the nuclear pores

119 tly reduced, suggesting that Leu29 and Leu36 are located at the dimer interface, contributing to the

120 bility density functions, whose center peaks are located at the distances between corresponding atoms

121 Mutations of residues 173 and 221, which are located at the entrance to the VFTD cleft binding si

122 her dopant contents have been identified and are located at the grain boundaries of the material.

123 e probes and septa for injection or sampling are located at the inlet and outlet of the cell chamber.

124 d W122-indole on different protein molecules are located at the interface at much shorter intermolecu

125 These proteins, termed Incs, are located at the interface between host and pathogen a

126 etween residues specific to each enzyme that are located at the interface between the fingers and the

127 acellular loops 1 and 3, respectively, which are located at the interface between the nucleotide bind

128 ds with the highest affinity for Hg(II) that are located at the interface between the outer membrane

129 at the canonical acetylcholine-binding sites are located at the interfaces between two pairs of subun

130 In lampreys, stretch receptor neurons (SRNs) are located at the margins of the spinal cord and activa

131 n the lipid bilayer, and peripheral proteins are located at the membrane surface.

132 tructure of E2/E1 revealed that all epitopes are located at the membrane-distal region of the E2/E1 s

133 SB, primarily defined as DNA repair factors, are located at the midbody, a transient structure in the

134 dementia, the majority of missense mutations are located at the N-domain D1 interface.

135 Both residues are located at the N-terminal helix-capping motifs (N-Ca

136 The residues R1 in S4 and E1 in S2 are located at the narrowest region of the omega-pore fo

137 These cyclic nucleotide-gated channels are located at the nuclear envelope and are permeable to

138 All loss-of-function variants are located at the PALB2 coiled coil (CC) or at the WD40

139 st that Ca(2+) sensors for vesicular release are located at the perimeter of VGCC clusters (<30 nm) a

140 t the serine protease domains of C1r and C1s are located at the periphery of the C1r2s2 tetramer both

141 Natural killer (NK) cells are located at the periphery of the lymph node, predomin

142 These mutated TASK-1 channels are located at the plasma membrane to the same degree as

143 ent of cell division, most plasmid molecules are located at the poles, resulting in efficient random

144 in, a ubiquitously expressed protease, which are located at the S1/S2 interface and at the S2' positi

145 The Jek1/Jek3 sequences are located at the same chromosomal locus and inherited

146 elements targeting different essential genes are located at the same genomic position, and one of the

147 vity to become phosphorylated and those that are located at the SPB.

148 ine residues, often called arginine fingers, are located at the subunit interfaces of the complex, wh

149 Those within NS3 and NS5 are located at the surface and/or within the NS5 dimer i

150 containing ~600 Pd atoms, where 45% of these are located at the surface.

151 The analyses show that 94 % of the Al atoms are located at the surfaces of the large-pore interlayer

152 nt shoot apical meristems (SAMs), stem cells are located at the top while cells specifying the stem c

153 the remainder of which are highly variable, are located at the two interfaces.

154 LEM-3 has previously been shown to be located at the cell mid-body, and we show here that h

155 ted with either of these host states tend to be located at the periphery of the metabolic network and

156 We validated sites predicted to be located at the protein-protein interface by using chi

157 s requires a cis-acting bipartite element (3'BE) located at the 3' untranslated leader.

158 th the addition and reduction reactions have been located at the B3LYP/6-311+G* level using acetone a

159 of 17OHP bound to the enzyme, the distal one being located at the entrance of the substrate access ch

160 The N-terminal moiety of the peptide is located at the active site, positioned optimally for

161 site in DR5 being (354)WEPLMRKLGL(363) that is located at the alpha2 helix and the loop between alph

162 The RACK1 binding motif in MCM7 is located at the amino acid 221-248.

163 Our results, which show that the MLD is located at the apex and the sides of each glycoprotei

164 This substitution is located at the base of a hinge between the RecA-like

165 The P2/3 cleavage site is located at the base of a narrow cleft and is not read

166 cranial end of the airway, the avian syrinx is located at the base of the airway at the split of the

167 ound that the region of actin polymerization is located at the base of the endocytic invagination, wi

168 KHARON is located at the base of the flagellar axoneme, where i

169 Immunolocalization revealed that KH1 is located at the base of the flagellum, within the flag

170 Indeed, the glucose transporter GLUT2 is located at the basolateral, vascular side, while SGLT

171 The cipA coding sequence is located at the beginning of a gene cluster containing

172 An RF ion trap/buncher is located at the beginning of the drift region, which m

173 sequently, in Wnt1 morphants, the blastopore is located at the border of the re-specified posterior-v

174 This element is located at the boundary of active and inactive chroma

175 -domain class III Fic proteins, the alphainh is located at the C terminus and its deletion relieves a

176 analysis indicated that the dimer interface is located at the C terminus and provided the first stru

177 Similarly, the N protein binding pocket is located at the C terminus of RdRp.

178 amino acid sequence containing Gly-Gly that is located at the C terminus of the D1-D2 linker functio

179 The heparin binding site is located at the C-terminal end of helix D and the adja

180 The pleckstrin homology (PH) domain of Lbc is located at the C-terminal end of the protein and is s

181 t a putative PEST motif (proteolytic signal) is located at the C-terminal region of AtWRI1(IDR) (3).

182 e 1-ethyl-2-benzimidazolinone (1-EBIO) class is located at the calmodulin-channel interface.

183 e piSi horizontal lineP bond, while the LUMO is located at the carbene moiety (cAAC or NHC).

184 d to the C-terminus, while a divalent cation is located at the catalytic site, acting as a cofactor.

185 The unique avian vocal organ, the syrinx, is located at the caudal end of the trachea.

186 e p.Leu104Val transmembrane isoform of KITLG is located at the cell membrane, as is wild-type KITLG.

187 Parental education is located at the center of global efforts to improve ch

188 A partially occupied U site is located at the center of the cluster.

189 In mass casualty events, radiologic imaging is located at the centre of patient management.

190 A pH probe is located at the chamber outlet.

191 The nucleus basalis is located at the confluence of the limbic and reticular

192 Surprisingly, although TAK1 is located at the crossroad of inflammation, immunity, a

193 lasmid-encoded coupling protein, TraD, which is located at the cytoplasmic entrance of the F-encoded

194 In yeast, the SEN complex is located at the cytoplasmic surface of mitochondria, w

195 Because the cap-snatching site of Gag is located at the cytoplasmic surface of the virion, whe

196 y accessible, when the key region for gating is located at the cytosolic side of the channels.

197 Here, we tested whether the Opi3 active site is located at the cytosolic side of the ER membrane, whi

198 WaaG is located at the cytosolic side of the inner membrane,

199 rotonation state of the E175 side chain that is located at the dimer interface and within hydrogen-bo

200 Modeling studies indicated that Cys-20 is located at the dimer interface near the DNA-binding s

201 e beta3alpha3 turn (residues 333-366), which is located at the dimer interface, undergo a rapid trans

202 f infected fetus with neonatal microcephaly, is located at the dimer interface.

203 In addition, histone H3K56, which is located at the DNA entry and exit points of a canonic

204 43, Thr-139, His-189, and structural waters, is located at the edge of PLP opposite the reactive Schi

205 the protein shell, and the F420-binding site is located at the end of the chain near the outside of t

206 hosphorus at a P-O distance of 2.06 angstrom is located at the end of the reaction path.

207 iple glycans and is highly sequence diverse, is located at the Env apex and stabilizes the trimeric g

208 s of the alpha1S270T startle mutation, which is located at the extracellular end of the pore lining M

209 The site of action is located at the extracellular vestibule of the recepto

210 sociated calsequestrin mutation, S173I, that is located at the filament-forming interface, and furthe

211 ost likely to occur if the deprotonated base is located at the first or last position in the sequence

212 His 212 is located at the fulcrum of these conformational change

213 band maximum or the minimum energy for holes is located at the high symmetric Z-point for both materi

214 The peptide binding site of TAP is located at the hydrophobic boundary of the cytosolic

215 In cardiac muscle, dysferlin is located at the intercalated disc and transverse tubul

216 k-center frequency suggests that the peptide is located at the interface beneath the lipid headgroup

217 oop motif at the C-terminal end of AC, which is located at the interface between CaM and the AC catal

218 the binding pocket of 1-EBIO and NS309 that is located at the interface between the channel and calm

219 This unidentified phase is located at the interface between the mature bone and

220 The single most important region is located at the interface between the transmembrane do

221 acetylcholine to an extracellular site that is located at the interface between two adjacent recepto

222 inal domain of primase, we found that Ile-85 is located at the interface in the NTD of DnaB that cont

223 Phylogenetic analysis indicated that NIH-CQV is located at the interface of Parvoviridae and Circovir

224 tly binds with FMN and Cu(II)-binding pocket is located at the interface of the NfoR dimer.

225 This reorganizes the active site, which is located at the interface of these domains, and adjust

226 ely 28-kb 3' regulatory region (3'RR), which is located at the most distal 3' region of the Ig H chai

227 A plastid transit peptide is located at the N terminus of OsGR3, and genetic trans

228 C-terminal helix H12, the EID1-binding site is located at the N terminus of the receptor, where EID1

229 initiated by the fusion peptide (FP), which is located at the N-terminal of gp41, the transmembrane

230 In contrast the LaO, which is located at the next sub-surface atomic layer, showed

231 ~680 km deep 2015 Bonin earthquake (Mw~7.9) is located at the northernmost edge of the overturning p

232 In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the

233 aused by the DCM-linked mutation, M8R, which is located at the overlap junction.

234 C101 is located at the P1' position of the NS2B/3 protease cl

235 ch binds the axonal Caspr/contactin complex, is located at the paranodal junction that is formed betw

236 EMRE is located at the periphery of the transmembrane domain

237 ferent in unstimulated cells, p63RhoGEF(580) is located at the plasma membrane and p63RhoGEF(619) is

238 We also observe that LAMP2 is located at the plasma membrane in clinical samples an

239 The sea lion visual cortex is located at the posterior side of cortex between the u

240 IL1RAPL1 protein is located at the postsynaptic compartment of excitatory

241 The centromere is located at the primary constriction of condensed chro

242 the significant SNPs, rs7905446 (T/G), which is located at the promoter region, also showed nominal s

243 Residue I50 is located at the protease flap tips, closing the active

244 The highly conserved residue H75 is located at the protomer interface.

245 P-A nucleosome, when the CENP-B box sequence is located at the proximal edge of the nucleosome.

246 DNA containing the transcription start site is located at the RNA polymerase (RNAP) catalytic centre

247 a, not only for ensuring that epsilon(irr,0) is located at the SIC plateau while RRR >= 150, but also

248 The Hi-C data showed that the EACBE is located at the sub-TAD boundary which separates the T

249 he subpellicular microtubules, whereas KHAP2 is located at the subpellicular microtubules and the bas

250 gands requires tryptophan 55 (Trp-55), which is located at the subunit interface on the complementary

251 f the eukaryotic large ribosomal subunit and is located at the surface of the ribosome.

252 involved in nuclear signaling, whereas Epac2 is located at the T tubules and regulates arrhythmogenic

253 Asp95 is located at the threefold central channel of the trime

254 surfaces triggered by the lectin FimH, which is located at the tip of bacterial type 1 pili.

255 V3 peptide and showed that the 2424 epitope is located at the tip of the V3 crown ((307)IHIGPGRAFYT(

256 late around the enzymatic active site, which is located at the top of the NA head.

257 ine-rich region of hitherto unknown function is located at the transition of the NC1 domain to the co

258 This mutation is located at the W-loop of actin, which has been implic

259 f LIM domain binding protein 3 (LDB3), which is located at the Z-lines of the sarcomere, at different

260 ries of approaches that indicate that ERManI is located, at the steady state, in quality control vesi

261 The metal ball was located at the 7 o'clock position in all controls.

262 igh CF site (48/113 sites in 17/18 patients) was located at the anterior/rightward LA roof, directly

263 points bringing the hand to the mouth, which was located at the boundary between the hand and face re

264 domain C with a Greek key beta-sandwich fold was located at the C terminus, and a carbohydrate-bindin

265 e greatest activity observed when the methyl was located at the C-6 position.

266 nt CD36 crystal structure showed that Pro191 was located at the exit/entrance gate of the lipid bindi

267 trongly suggested that this new binding site was located at the interface between the alphaC helix an

268 nding to cellular receptors; and residue 295 was located at the interface of two monomeric VP1 protei

269 The site of enzymatic cleavage was located at the less conformationally hindered positi

270 econd target region requiring close homology was located at the other end of the guide::target duplex

271 The tumor was located at the pancreatic head in 7 patients and the

272 ookinetes, sporozoites, and merozoites, MyoA was located at the parasite periphery.

273 MyoA was synthesized in mature schizonts and was located at the periphery of segmenting merozoites, w

274 dMyD88 was located at the plasma membrane by a process dependen

275 ic kidney disease (pkd1)-knockout mice, CFTR was located at the plasma membrane, consistent with its

276 In aggregates, the cap was located at the point of attachment of the PS-positiv

277 It was supposed that the mutation was located at the solvent front and might hinder the dr

278 The biliary diverticulum was located at the upper, middle, and lower part of the

279 Importantly, CEFIP was located at the z-disc and was up-regulated in severa

280 ntained when the space-occupying substitutes were located at the 7-position.

281 The cross-linked residues were located at the bottom of transmembrane domain 5 (TM

282 and the majority of VP1 amino acid mutations were located at the capsid surface.

283 Tumors were located at the ciliary body in 21 eyes (21%), juxta

284 inferolateral scar-related VT, target sites were located at the epicardium in 5 patients (63%) and i

285 Lesions were located at the hepatic flexure in 4 patients (36%),

286 rointerfaces (formed on the laser exit side) were located at the mouth of the pore in hemispherical g

287 tations affecting function more than binding were located at the periphery of the binding site and di

288 In contrast, engineered mutants were located at the plasma membrane and able to transpor

289 G106R or L214R mutated channels were located at the plasma membrane to the same degree a

290 The dendriform DCs were located at the sub-basal space where the nerve plex

291 Fifty-nine of the bipartite fragments were located at the superolateral quadrant of the patell

292 In all eyes, CNVs were located at the temporal margin of the coloboma clos

293 Populations were located at the treeline across a latitudinal gradie

294 The fatty acid headgroups were located at the unit cell boundary with their acyl c

295 Most neurons were located at the venous pole in a plexus around the s

296 The expanded representations were located at the vertical meridian borders between vi

297 alter receptor signaling and cause disease, are located at these conserved contact and activation ho

298 At least two vestibular areas are located at this site: the parietoinsular vestibular

299 two of these variants, rs35278 and rs165940, are located at transcription factor-binding sites, and d

300 When active sites are located at unconfined type-(i) environments, the rat