ライフサイエンスコーパス: be located in

1 Cell bodies of these neurons were located in 11 different clusters in the cell body r

2 in the replication sample, including 19 that were located in 11 loci not reported to contain allergy

3 conserved adenylate-uridylate-rich elements (ARE) located in 3'untranslated regions (UTR) to mediate

4 mortality) of fully adjusted mortality, 60% were located in 3 states: Oklahoma, Texas, and New Mexic

5 mostly in familial BC individuals (7/9) and were located in 5 genes: ATM (3), BRCA2 (1), CHEK2 (1),

6 tified 1429 PSSs, among which 23.5% and 5.4% were located in 5 untranslated region (uPSS) and interge

7 ases were present in 18 patients (31.0%) and were located in 52 of 375 templates (13.9%).

8 uence analysis suggested that these residues are located in a consensus region in many GH31 family me

9 es encoding the metallothionein protein Cup1 are located in a tandem array on chromosome VIII.

10 Other retrogradely labeled neurons are located in a variety of brain regions, including the

11 Both receptors are located in A-IC apical membranes, and adenosine inje

12 27) that remains virtually unstudied despite being located in a highly conserved region proximal to t

13 rs34861192 is located in a 100 bp region found to be methylated in

14 Each binding site is located in a crevice between the C-terminal domains o

15 onon spectra suggests that atom type 8, that is located in a more open space of the structure, domina

16 lates and revealed that the new ACE1 cluster is located in a newly formed and transposable element-ri

17 Our findings reveal that tet(W) is located in a novel integrative and conjugative elemen

18 Asn200 is located in a pocket of the C2 group, and its side cha

19 The mutation is located in a poorly understood region of the polymera

20 in T (cTnT) mutation Delta160Glu (Delta160E) is located in a putative "hinge" adjacent to an unstruct

21 ntial climate and land-use changes if a lake is located in a region with greater access to clean wate

22 demonstrate that the GDF15 receptor, GFRAL, is located in a subset of cholecystokinin neurons which

23 The p.Glu610* mutation was located in a gap area (amino acids 470 to 625) withi

24 of the clinic, which had no Latino staff and was located in a middle-class neighborhood far from his

25 e four positions where potentiation occurred were located in a cluster on one side of the helix.

26 Specifically, although in 2005 852 hospitals were located in a rural area, that number had decreased

27 th prevalence above 2.0% in the first survey were located in a stretch along a 2000 km of the Amazon

28 The compound is located in an allosteric, mostly hydrophobic cavity n

29 The S324Tfs*3 variant is located in an alternatively spliced micro-exon encodi

30 high linkage disequilibrium with rs73227498, is located in an enhancer region downstream of coding tr

31 proven to be a pseudogene in the cat genome, is located in an evolutionary breakpoint region of the g

32 t autologous neutralizing epitope in rabbits is located in an exposed region of the heavily glycosyla

33 Rs7692387 is located in an intronic site that modulates GUCY1A3 pr

34 We show here that the intron conversion is located in an open chromatin form and binds more stro

35 One of the replicated variants, rs178252, is located in an open chromatin region and resides in th

36 ed BPCI SNFs were for-profit facilities, 85% were located in an urban area, and 85% were part of a la

37 a-associated single-nucleotide polymorphisms are located in and affect activity of the promoter of LO

38 Where schools are located in areas with low visibility of scientific c

39 tomy centres that closed were more likely to be located in areas with stronger competition (highest S

40 th average-value peers, high-value practices were located in areas with a relatively higher proportio

41 ylase (TH)-expressing cells, but tac3a cells were located in areas with dense TH fibers.

42 All were located in areas with high densities of shale-gas o

43 nd control participants and the highest PAFs were located in ARMS2 (rs3750846) and CHF (rs570618 and

44 (P < 10(-5)), most of the EoE risk variants are located in between genes (36.7%) or within the intro

45 In most organisms, proteasomes are located in both the nucleus and cytoplasm.

46 cotinamide phosphoribosyltransferase (NAMPT) is located in both the nucleus and cytoplasm and has mul

47 iceptive information from the posterior dura are located in C2-C4 spinal cord and that their cutaneou

48 are considered to be most vulnerable; these are located in Central America, Southeast Asia and in th

49 Umbria is located in Central Italy and took the name from its a

50 cell type 50-60 % of all membrane ceramides are located in ceramide-rich platforms (CRPs) with a siz

51 Most GWAS hits are located in cis-regulatory regions, but the underlyin

52 piped water connection and 73% of households are located in cities, close to networked supply.

53 Insulin producing pancreatic islets are located in close proximity to the pancreatic duct an

54 one subunit, and Asp426 on a second subunit, are located in close proximity.

55 r subunits, where Asp506, Glu568, and Asp571 are located in close proximity.

56 nnected with a higher probability and should be located in close vicinity to save wiring.

57 coordinated fashion, but without necessarily being located in close proximity to each other.

58 otably, one is specific to SARS-CoV-2, which is located in close proximity to the receptor binding do

59 dred with a novel K181E TDP-43 mutation that is located in close proximity to the RRM1 domain.

60 at several proteins with divergent functions are located in clusters of differing size in the membran

61 entage of global reserves and resources that are located in complex ESG contexts (i.e., with four or

62 Neurons with fbRFs are located in cortical layers that receive strong feedb

63 ctive stimulation of targeted neurons, which are located in deeper structures of the nervous system,

64 those at telomere ends, suggesting that they are located in different regions within the chromosome t

65 Cells within each class were located in different sublaminae.

66 Vertebrate olfactory sensory neurons (OSNs) are located in direct contact with pathogens; however, O

67 o clusters of closely spaced serine residues are located in disordered domains flanking a 12-amino ac

68 In vivo, the inhibitors were located in distinct zones in relation to the front

69 ons associated to more generalized symptoms, being located in domains that emerge anew in high diseas

70 CSF-cNs in the spinal cord of C57Bl/6N mice is located in ectopic distal ventral position.

71 red core protein fold but whose active sites are located in entirely different regions, illustrating

72 However, some elements are located in euchromatic regions throughout the genome

73 , two-pore domain, and related K(+) channels are located in eukaryotic membranes rich in cholesterol.

74 The mutation c.9886A>G was located in exon 9 leading to the missense mutation p

75 Human RBMY1 genes are located in four variable-sized clusters on the Y chr

76 issense variants are absent from gnomAD, and are located in functional domains of the encoded protein

77 t some mutation-induced splicing alterations are located in genes important in tumorigenesis (ATRX, B

78 Although the majority of these SNPs are located in genes of unknown function, one SNP is loc

79 QTLs) (influencing GNG11, RGS6 and NEO1), or are located in genes preferentially expressed in the sin

80 Additional DMPs were located in genes associated with tumor development

81 identified variants with generalized effect were located in genes, including five nonsynonymous vari

82 These SNP were located in genomic regions containing a total of 68

83 ntal health professionals are more likely to be located in higher-income communities.

84 terfaces between subunits; cholesterol poses are located in hollows, largely within these clefts.

85 ported genetic variants associated with DHRs are located in human leukocyte antigen genes and genes i

86 ith the potential for enhancer activity that are located in inaccessible, closed chromatin regions.

87 ad neuroticism-related X chromosome variants were located in intergenic regions (n = 397).

88 er, little is known about where EBV episomes are located in interphase cells.

89 MtFPN2 is located in intracellular membranes in the nodule vasc

90 One association signal is located in intron 3 of VLDLR; rs3780181-A is a risk a

91 nstrates that an erythroid-specific enhancer is located in intron 7 of lamprey nprl3, which correspon

92 These three SNPs are located in intronic regions of CADM2, LINGO2 and EP3

93 y, a BBS-associated mutation of BBS2 (R632P) is located in its alpha-helical domain at the interface

94 Glu571 of CRM1 is located in its nuclear export signal (NES)-binding gr

95 hese remnants of early Earth differentiation are located in large seismically anomalous regions corre

96 Further studies show that DSTYK is located in late endosomal/lysosomal compartments and

97 tion that the synaptic targets of isoflurane are located in local cortical circuits rather than on th

98 nly distributed and a disproportionate share is located in low-income, non-white, and Hispanic neighb

99 ent human immunodeficiency virus 1 infection are located in lymphoid tissues that are difficult to ac

100 take in the vessel wall on autoradiographies was located in macrophage-rich regions of atheroscleroti

101 e SNP most significantly associated with RBA is located in MAPT gene.

102 Stellwagen Bank National Marine Sanctuary is located in Massachusetts Bay off the densely populate

103 ers outgas carbon with higher delta(13)C and are located in mature continental arcs that have accrete

104 dy shows that the majority (75%) of bacteria are located in mesopores (<10 mum).

105 nucleotide resolution the m(5)C sites, which are located in multiple clusters throughout the MLV geno

106 ervated by sensory neurons whose cell bodies are located in multiple ganglia associated with the brai

107 The additional, delocalized Li-ion density is located in new high energy lattice sites that provide

108 ted that a large proportion of risk variants are located in non-coding regions and remain unexplained

109 d in genome-wide association studies (GWASs) are located in non-coding regions of the genome and thou

110 ASs) indicated that the majority of the TASs are located in nongenic regions, and the genetic effects

111 ctivated pLckCre was detected, many of which were located in nonlymphoid organs as well as precommitt

112 The first, PQ1, is located in one cytb(6) f monomer near the PQ oxidatio

113 Of these DMCs, 52% were located in one 15.5-Mb locus on chromosome 13, whic

114 We estimated that 25-70% of causal variants were located in open-chromatin regions, depending on the

115 Upper bay stations, which are located in or near the estuarine turbidity maximum,

116 in the spike protein, whereas most epitopes were located in ORF1ab or the nucleocapsid protein.

117 nees can feel isolated from their peers whom are located in other hospitals and can find it difficult

118 d by particular gene expression combinations were located in periventricular, intermediate and superf

119 KEY MESSAGE: Pru p 3, a peach LTP, is located in pollinated flower styles and secreting dow

120 alth treatment facilities are more likely to be located in poorer communities, whereas office-based p

121 Some of the most affected reef ecosystems are located in poorly monitored waters, and thus, the ex

122 errant brain activity related to psychopathy is located in prefrontal, insular, and limbic regions.

123 showed that a calmodulin binding site (CBS) was located in prestin's C-terminal, specifically within

124 atial activity of Wnt/beta-catenin signaling is located in presumptive dorsal cells from cleavage to

125 The TECS services are located in primary care clinics and provide basic sc

126 and attention-deficit/hyperactivity disorder are located in protein-coding exons, indicating a more s

127 This occurs mostly when the stenosis is located in proximal and middle coronary segments and

128 s, whereas mutations affecting viral sensing are located in proximity to DNA binding regions, suggest

129 iding in a home that received Flint water or was located in proximity to several Flint cooling towers

130 50% of tuberculosis microscopy laboratories were located in public-sector-basic health units and reg

131 s regenerative state, mpeg1-expressing cells are located in regions containing regenerative Muller gl

132 oniae PBP2X suggests that some substitutions are located in regions functionally important in related

133 The cognitive and affective networks are located in regions of cingulate cortex.

134 Among the identified loci, 21 were located in regions previously reported for N traits

135 ons of high eQTL density were more likely to be located in regulatory elements (transcription factor

136 iated single nucleotide polymorphisms (SNPs) were located in regulatory regions of candidate genes th

137 , tree-in-bud appearance and the main lesion being located in S1, S2, and S6 lung segments were signi

138 genes, TRIM8 (Tripartite motif containing 8) is located in SCZ-associated genetic locus and is aberra

139 alter GH secretion and neurons expressing TH are located in several brain areas containing GH-respons

140 In macaques, these face patches are located in similar parts of inferotemporal cortex ac

141 Key residues in the polymerase are located in similar positions to those of the initiat

142 The top DMP was located in SLC7A11A, a gene involved in cystine/glut

143 GAT-3' sequences in the nucleosome when they are located in solvent accessible, consecutive major gro

144 te that areas with highest deposition values are located in southern Scandinavia and southeastern Bul

145 glomeruli with similar tuning curves tend to be located in spatial proximity in the dOB.

146 th similar physico-chemical MRR descriptions being located in spatial proximity.

147 sicular glutamate transporter 2 (VGlut2) and are located in subcortical brain regions is sufficient a

148 Within ssE3s structural disorder tends to be located in substrate binding and domain linking regio

149 Although approximately 40 genes are located in the 15q11.2-q13.3 region, overexpression

150 beta-domain, whereas Cd(2+) ions of Cd(4)-MT are located in the alpha-domain.

151 esidues contributing most to MARCH9 activity are located in the alpha-helical portions of TM1 and TM2

152 In GBid, the constant domains of the Fabs are located in the backbone of the phagemid vector and t

153 s are very different; Ag(+) ions of Ag(4)-MT are located in the beta-domain, whereas Cd(2+) ions of C

154 Two of these mutations are located in the C-terminal region of mu1, which has n

155 idine/cytidine kinases, UCK1 and UCK2, which are located in the cytosol and are responsible for the m

156 V(H) locus, whereas the RSS-associated sites are located in the D(H)-proximal region.

157 Primary cilia are located in the dental epithelium and mesenchyme at e

158 noted that the intergenic and upstream sites are located in the distal portion of the V(H) locus, whe

159 nflammatory dendritic epidermal cells (IDEC) are located in the epidermis of AD patients and contribu

160 Most of the disease-causing mutations are located in the extended cytoplasmic C-terminus of Sl

161 Approximately 70% of these tumours are located in the gastrointestinal system (GI), followe

162 (SVs), the breakpoints of fusion genes (FGs) are located in the gene bodies.

163 Most of the TRSs are located in the genomic 3' region, but some are in th

164 titute the exclusive sword transcriptome and are located in the genomic region associated with this t

165 The major antigenic sites of HA are located in the globular head subdomain, which is hig

166 V2a interneurons are located in the hindbrain and spinal cord, where they

167 Two of these variants are located in the HMG domain and abolish SOX6 transcrip

168 First, two Cu atoms are located in the inner 7-atom decahedral kernel (M(7),

169 pulation with identified missense mutations, are located in the interface between the transmembrane d

170 GL-dSACs are located in the internal plexiform layer, where they

171 in the metal lattice imply that the B atoms are located in the interstitial sites.

172 The majority of Prph2 mutations are located in the large intradiscal loop (D2), a region

173 uggests, but as many as 30% of proteins that are located in the long tails suffer low predictive perf

174 These residues are located in the membrane-proximal region of the N ter

175 A majority of FTD-causing tau mutations are located in the microtubule-binding domain, but how t

176 Most of these suppressors are located in the movable core domain, but also in the

177 es and that most of the sequence differences are located in the N-terminal region.

178 The Y247H and E248K mutations are located in the NH(2) -terminal M-motif of sMyBP-C.

179 Nearly all disease-associated risk loci are located in the non-coding region of the genome and t

180 Ca(2+) channels are located in the plasma membrane and intracellular mem

181 and ChR2; these light-gated cation channels are located in the plasma membrane.

182 cids affected by the variants in this report are located in the pre-M1 helix, transmembrane domain M3

183 The only radially far migrated shh-GFP cells are located in the preglomerular area.

184 were in complete linkage disequilibrium, and are located in the PRLR intracellular domain, occurred w

185 ues, K10, K26, K42, E43, K46, and K48, which are located in the region between the N-terminus and the

186 utations associated with the HPT-JT syndrome are located in the region encoding CDC73-NTD.

187 ry cells (SCCs) and their innervating fibers are located in the respiratory system of many vertebrate

188 p.Ile1033Met and p.Ile1040Thr, both of which are located in the S6 transmembrane domain of the TRPM4

189 lated expression of enhancers and genes that are located in the same TAD.

190 ost importantly, residues 258-269 of securin are located in the separase active site, illuminating th

191 ed with estimated glomerular filtration rate are located in the SHROOM3 gene, suggesting that SHROOM3

192 They are located in the stereocilia of hair cells and opened

193 ese primate-specific interlaminar astrocytes are located in the superficial layer and project long pr

194 When their nearest neighbors are located in the tree of life, many of the organisms r

195 PCR primers are located in the unique regions bordering each repeate

196 nes, we showed that agrp1-expressing neurons are located in the ventral periventricular hypothalamus

197 lth treatment facilities were less likely to be located in the communities in the highest vs lowest i

198 can arise from different germline genes and be located in the heavy or the light chain.

199 ing pregnancy were more likely themselves to be located in the highest HEI quartile at age 14 years (

200 data, we demonstrated that a similar hub can be located in the human rACC.

201 At2g44920 is predicted to be located in the thylakoid lumen although its biochemic

202 -binding site of human CD40L is predicted to be located in the trimeric interface by docking simulati

203 DiGeorge syndrome critical region 2 (DGCR2) is located in the 22q11.2 locus, whose deletion is a maj

204 SNP rs2072920 is located in the 3'-UTR of WNT4 and SNP rs11918967 is l

205 binding targets of the protein, of which one is located in the 5'-untranslated leader and the other i

206 cockroach, Rhyparobia (Leucophaea) maderae, is located in the accessory medulla (AME).

207 hat the binding site for the substrate eEF-2 is located in the C-terminal domain of eEF-2K, a region

208 angstrom resolutions, revealing that His-257 is located in the catalytic site and that the substituti

209 The domain of CtIP required to promote DNA2 is located in the central region lacking in lower eukary

210 This variant is located in the coding region of all nine YAP1 splicef

211 The mutation is located in the converter domain, a key region of comm

212 ul sources of radiation whose central engine is located in the core of the host galaxy.

213 The active site is located in the core of the protein at the base of a l

214 XIW1 is located in the cytoplasm and nucleus.

215 Apc is located in the cytoplasm downstream of Fzd7 in the Wn

216 long noncoding RNA ANRIL, the gene of which is located in the disease-associated 9p21 locus.

217 nal amplification (FISH-TSA), that this gene is located in the distal region of the B24 chromosome va

218 ocated in genes of unknown function, one SNP is located in the DNA binding site of a member of the Pl

219 This site is located in the extracellular loop L3, showing that it

220 asmalemma vesicle-associated protein (Plvap) is located in the fenestral diaphragm and is thought to

221 osed of a single peptide and protonated Glu8 is located in the fibrillar core.

222 NLR-1 is located in the gap junction perinexus, a region adjac

223 The variant is located in the gene encoding serine protease inhibito

224 The glycan-binding site of T1 sigma1 is located in the head domain and is partly occluded by

225 mals, the central circadian pacemaker, which is located in the hypothalamic suprachiasmatic nucleus,

226 We show that PhIL1 is located in the IMC in all three invasive (merozoite,

227 CADs are homodimers, the active center is located in the interface between 2 distinct subdomain

228 Cyt c, a heme containing metalloprotein is located in the intermembrane space of mitochondria an

229 We show that this lipase is located in the intermembrane space of the mitochondri

230 y, we show that, in mitochondria, huntingtin is located in the intermembrane space, that mHTT binds w

231 ted in the 3'-UTR of WNT4 and SNP rs11918967 is located in the intron of WNT5A.

232 C(60)(*-)-ZnP(*+)-Fc charge-separated state is located in the inverted region, while that of the dis

233 primarily transcellular and the main barrier is located in the lipid layers.

234 OATP1B3-1B7 is expressed in hepatocytes and is located in the membrane of the smooth endoplasmic ret

235 yme ghrelin O-acyl transferase (GOAT), which is located in the membranes of lipid trafficking vesicle

236 emonstrated that (i) the heme-binding region is located in the MF6p/FhHDM-1 C-terminal moiety, which

237 to demonstrate that this centre of rotation is located in the middle facet of the subtalar joint.

238 Ursu Lake is located in the Middle Miocene salt deposit of Central

239 N582 is located in the middle of a short 310-helical turn (D5

240 e identify and characterize an enhancer that is located in the middle of the V gene region of the imm

241 PtMACAD1 is located in the mitochondria.

242 Their component enrichment is located in the nucleolus.

243 re, we show that the function of PAP1, which is located in the nucleus, is to polyadenylate non-codin

244 instant sense of the environmental geometry is located in the OPA.

245 When the primary tumour is located in the pancreas, it is associated with a risk

246 olocalization studies revealed that MtMOT1.3 is located in the plasma membrane of nodule cells.

247 es studied and, in three of these, the break is located in the same position as the protostome break

248 The variant is located in the second intron of the ABCA12 gene, whic

249 The master circadian clock is located in the suprachiasmatic nuclei (SCN) of the hy

250 The master circadian pacemaker in mammals is located in the suprachiasmatic nuclei (SCN) which reg

251 It is located in the surface-exposed loop of the carboxy-te

252 The mutation is located in the tail segment and is predicted to disru

253 on microscopy analysis confirmed that SBDCP1 was located in the amyloplasts.

254 As in SNM1A, only one zinc ion was located in the Artemis active site.

255 This alpha-helix was located in the C-terminal region and included residu

256 f ciprofloxacin, a higher amount of compound was located in the cytoplasm than in the periplasm (592

257 domized for the SBTS group whose obstruction was located in the descending colon had a better TTP com

258 ique regions bordering the repeated sequence was located in the expected chromosomes, using the perfe

259 The second most significant locus was located in the FOXP2 gene in chromosome 7 with P = 2

260 On ultrasound, the left testis was located in the inguinal canal, the right kidney was

261 Sequence analysis demonstrated that FLRL2 was located in the intronic region of the Arntl gene, an

262 The third locus was located in the LINC01572 gene in chromosome 16 with

263 e consistently associated across all cohorts was located in the long non-coding RNA growth arrest spe

264 d lower activity were measured when tyrosine was located in the middle of the peptide chain.

265 tivation (for whole-brain analyses, the peak was located in the right caudate) to unexpected reward t

266 ss both samples the point of maximal atrophy was located in the same region of the left temporal pole

267 The virulent proteins targeted by the drugs were located in the cytoplasm, which would further add t

268 ed from 23 regions of interests (ROIs) which were located in the following areas: level of basal gang

269 has strongly suggested that NS binding sites were located in the GABA(A)R transmembrane domain; howev

270 Y experiments showed that the aryl benzoates were located in the hydrophobic core of the micelle.

271 d, and NOESY experiments showed that phenols were located in the hydrophobic core of the micelle.

272 Most TRM cells were located in the insulitic lesion in the endocrine-ex

273 All mutations were located in the last or penultimate exon, suggesting

274 a total number of 410 electric rotors, 47.8% were located in the left atrium and 52.2% in the right a

275 In this study, whenever two main canals were located in the MB roots of the maxillary first mola

276 that the majority of U(S)3-responsive genes were located in the MDV repeat regions.

277 fied in both the CpG site and DMR approaches were located in the MHC region on chromosome 6, which pl

278 These flat, subretinal lesions were located in the mid or far periphery and had well-de

279 of these, 45 proteins and 18 phosphopeptides were located in the mitochondria.

280 Drusen-like deposits were located in the nasal, temporal, inferior, superior,

281 Most affected communities were located in the northwest inland part of the country

282 ns labeled by tracer injections in the medOB were located in the OB, the posterior tuberculum, and th

283 A vast abundance of TH-ir somata were located in the opisthosomal neuromeres, the largest

284 Most of the labeled neurons were located in the posterior-ventral part of the claust

285 tants indicated 7 of 9 mutants whose lesions were located in the Rho-GAP domain were deficient for Rh

286 ospitalized patients, and 65% of the lesions were located in the right liver lobe.

287 iptions written annually per ophthalmologist were located in the southern United States.

288 Notably, only 3 of the 29 shared epitopes were located in the spike protein, whereas most epitopes

289 Many of these value-coding neurons were located in the suprageniculate nucleus (SGN).

290 , four residues (N251, A263, I299, and F387) were located in the TIM barrel around the active site in

291 nown to be involved in carotenoid metabolism were located in this QTL- region: beta-carotene oxygenas

292 KHARON is located in three distinct regions of the cytoskeleton

293 Fifty-five of the replicated pQTLs are located in trans.

294 , p.Cys390Arg, p.Thr391Ile, and p.Thr391Pro) are located in two conserved motifs of the RecA-2 domain

295 ting two different catalytic activities that are located in two distinct domains.

296 itol trisphosphate (IP(3)) and ryanodine may be located in two functionally distinct Ca(2+) stores.

297 vealed that all chondroitin attachment sites are located in unstructured regions.

298 The tip of the appendix may be located in various areas of the abdominal cavity due

299 nnel (ENaC) subunits (alpha, beta and gamma) are located in vasopressin (VP) magnocellular neurons in

300 uman population density was higher, and that were located in wealthier countries, had higher social m