ライフサイエンスコーパス: be needed to

1 Improved drug regimens are needed to accelerate elimination of lymphatic filari

2 Improved treatment for onchocerciasis is needed to accelerate onchocerciasis elimination in Af

3 We propose that a broader framework is needed to account for how people balance different so

4 upport, along with prevention interventions, are needed to achieve HIV epidemic control.

5 r pathology-driven clinical trial approaches are needed to achieve this goal.

6 Effective implementation strategies are needed to achieve widespread use of these life-savin

7 scale patterns of K(S) and its major drivers is needed to achieve a better understanding of how plant

8 Interventions are needed to address the HCV-opioid syndemic in this re

9 nd observational studies, additional studies are needed to address this safety concern.

10 replication studies among nulliparous women are needed to allay concerns about confounding by reprod

11 he efficacy of spinal cord stimulation (SCS) is needed to alleviate the burden of chronic pain and de

12 sessments of vegetation responses to drought are needed to anticipate, manage, and potentially mitiga

13 viridae family that may not bind sialic acid is needed to anticipate their zoonotic potential and to

14 Longitudinal studies are needed to ascertain the significance of the differen

15 We suggest that further work is needed to ascertain the significance of oral mycobiom

16 of the main targets of VPA, but further work is needed to ascertain this effect.

17 Phase 3 trials are needed to assess clinical efficacy.

18 the unvaccinated immunocompetent population, are needed to assess disease burden and the potential im

19 ormal CKD surveillance programs in Nicaragua are needed to assess the overall burden of CKD nationall

20 Periodic benchmarks of global discards are needed to assess the performance of reduction effort

21 Further studies are needed to assess the secrets between photons and the

22 Improved methods are needed to assess the structure and activity of lesio

23 rom studies of over-the-counter CBD products are needed to assess whether the conclusions drawn from

24 Tools are needed to assess whether these drugs benefit patient

25 , and effects of fallow soils, but more data is needed to assess their importance.

26 al effects, careful handling of missing data is needed to avoid bias.

27 Thus, new cooperative modes of governance are needed to balance geopolitical, societal, and enviro

28 progression, and lower hospitalization risk are needed to benefit patients and reduce CKD's economic

29 cancer nurse specialist-patient interaction are needed to better ascertain impacts on long-term pati

30 fections, more robust and reliable estimates are needed to better quantitate the occurrence and under

31 tive, cost-efficient tools to detect amyloid are needed to better understand any potential routes of

32 Long-term studies are needed to better understand the dosimetry and health

33 icariance of Caribbean and Pacific lineages, are needed to better understand the evolutionary history

34 ol plan is essential, although national data are needed to better understand the magnitude and geogra

35 Further studies are needed to better understand the mechanisms of these

36 More research is needed to better understand differences in estimated

37 Future research is needed to better understand mechanisms leading to int

38 Longer follow-up is needed to better understand the effect of COVID-19 on

39 ls to apply randomization to real-world data are needed to build the best evidence base in cardiovasc

40 Future work is needed to build on this early attempt through replica

41 res of vision-related quality of life (VQoL) are needed to capture age-specific concerns about the im

42 In conclusion, additional research is needed to characterize the factors mitigating cellula

43 Additional work is needed to characterize the pathophysiology and to ide

44 nted since 2016, longer observational period is needed to clarify the exact severe complications decr

45 More research is needed to clarify the source of this imprecision.

46 , indicating that new therapeutic approaches are needed to combat bacterial pathogens.

47 therapeutic targets within serotonin neurons are needed to combat these disorders.

48 declines by 15%, while a 20% increase in NPP is needed to compensate that loss.

49 ific to SARS-CoV-2 (IgA) in saliva and serum is needed to complement tests that detect immunoglobulin

50 ion, diet and lifestyle intervention studies are needed to confirm our findings.

51 es and the development of frailty, more data are needed to confirm our results.

52 er of patients and a longer follow-up period are needed to confirm our results.

53 Well-powered studies are needed to confirm that NINM techniques as an alterna

54 inflammation in mice, and additional efforts are needed to confirm the beneficial effects of TMOP on

55 Large prospective studies are needed to confirm the long-term complication profile

56 Further studies are needed to confirm the nonsignificant trend towards a

57 Double-blinded sham-controlled trials are needed to confirm the remission rate observed in thi

58 Further studies are needed to confirm these findings and realize the pot

59 Future clinical trials are needed to confirm these findings.

60 Further large-scale studies are needed to confirm these findings.

61 ials including the use of either agent alone are needed to confirm these results.

62 Further studies with a large number of cases are needed to confirm this finding, especially with rega

63 renal toxicity; however, additional studies are needed to confirm this finding.

64 patient population, although further studies are needed to confirm this.

65 Further research is needed to confirm these results.

66 address this deficiency, but empirical data are needed to constrain their representation of particle

67 -economical alternatives to Wittig chemistry are needed to construct olefins from carbonyl compounds,

68 Additional interventions are needed to control and eliminate malaria.

69 Multidisciplinary teams are needed to coordinate care for pregnant women with ci

70 Versatile and precise genome modifications are needed to create a wider range of adoptive cellular

71 highly efficient genome editing technologies are needed to create genetic variation resources for fun

72 nic disease and/or promote healthy lifestyle are needed to decrease the prevalence of frailty and pre

73 Larger studies are needed to define predictors of durable response in p

74 Further studies are needed to define the nature of hiatal and crural dia

75 erstanding of JCPyV-induced PML pathogenesis is needed to define determinants that predispose patient

76 Further research is needed to define the role of asymptomatic hyperuricae

77 Additional research is needed to define the standards for palliative care in

78 th higher numbers of age-matched individuals are needed to definitively understand the impact of BMI

79 ease, intravascular imaging techniques might be needed to delineate the underlying aetiology, togethe

80 Studies in animal models are needed to demonstrate whether neurological syndromes

81 Further work is needed to demonstrate accuracy when implemented as a

82 Machine learning feature selection methods are needed to detect complex interaction-network effects

83 New approaches are needed to detect, treat, and prevent enteric infecti

84 Over a decade is needed to detect the consistent effects of no-till.

85 Although longitudinal studies are needed to determine causal associations between thes

86 Future studies are needed to determine how best to implement this evolv

87 Randomized controlled trials are needed to determine the appropriateness of specific

88 Future studies are needed to determine the cost-effectiveness of perfor

89 Longer and larger trials are needed to determine the durability and safety of rof

90 Studies are needed to determine the long-term effects of bariatr

91 Studies are needed to determine the mechanisms of mucosal dysreg

92 Contemporary randomized controlled trials are needed to determine the optimal revascularization st

93 Further studies are needed to determine the optimum anti-Xa heparin acti

94 creen active ingredients; additional studies are needed to determine the systemic absorption of addit

95 tion between KS and asymptomatic individuals are needed to determine whether ADCC has a role in preve

96 Further studies are needed to determine whether statin use and/or dyslip

97 Studies are needed to determine whether these bacteria contribut

98 umans strongly support this, further studies are needed to determine whether this mechanism explains

99 Future mechanistic studies will be needed to determine the precise functional effects of

100 Although further research is needed to determine causality, our study suggests tha

101 However, further consideration is needed to determine if there is sufficient patient lo

102 More research on population-level prevalence is needed to determine the burden of trauma symptoms and

103 Further work is needed to determine the causal effect of smoking on M

104 However, further research is needed to determine the clinical importance of this d

105 Further research is needed to determine the effectiveness of individual a

106 Further research is needed to determine the potential clinical impact of

107 Additional research is needed to determine which individuals may be most lik

108 ining workshop, though further investigation is needed to determine why only a minority of those trai

109 where urgent biodiversity monitoring efforts are needed to develop more accurate knowledge on biodive

110 elopment; therefore, a programmatic approach is needed to develop a framework for biomarker-driven co

111 o discuss areas in which additional research is needed to develop new approaches for prevention and t

112 chanistic understanding of human memory that is needed to develop therapies for human memory disorder

113 -matched control DNA and additional analysis is needed to distinguish somatic and unfiltered germline

114 Uniform reported outcome measures are needed to draw more definitive conclusions on transp

115 estry- or race-specific reference panels may be needed to draw correct inference in ancestrally diver

116 DNA replication is needed to duplicate a cell's genome in S phase and se

117 abitat conditions on bee pathogen prevalence are needed to effectively conserve pollinator population

118 Further research is needed to elucidate the appropriate indications for t

119 Further research is needed to elucidate whether upregulation of ACE2 expr

120 ms of nature reserves connected by corridors are needed to enable the dispersal of flora and fauna.

121 Evidence from high-quality CDS studies is needed to enable and support this vision of CDS-facil

122 Strategies are needed to encourage clinicians to pursue hepatology,

123 Additional strategies are needed to ensure long-term freedom from AF recurrenc

124 find that 400,000 excess White deaths would be needed to equal the best mortality ever recorded amon

125 Further studies are needed to establish its efficacy against current sta

126 However, more research is needed to establish the best treatment options for th

127 Further work is needed to establish the efficacy of cloth masks at bl

128 Further research is needed to establish the impact of technology on progr

129 mercially available FEVAR, but further study is needed to establish their long-term durability.

130 Although further work is needed to establish what causes these rib motions, ac

131 Future studies are needed to evaluate the impact of optimal cardiovascu

132 l-free tools that can modulate cell function are needed to evaluate the role of astrocytes in brain p

133 Prospective trials are needed to evaluate these therapeutic opportunities t

134 Ongoing high-quality educational research is needed to evaluate the impact of these initiatives.

135 A prospective randomised trial is needed to evaluate whether a second IVIg course impro

136 However, larger studies are needed to examine these findings in more detail to a

137 Research is needed to examine the impact of the pandemic-related

138 find that a J( pai) = 5/2(-) spin assignment is needed to explain the proton-emission pattern observe

139 Further well-designed studies are needed to explore its longer-term safety.

140 lenging regions, such as coils, fewer decoys are needed to explore satisfactorily conformation spaces

141 Further research is needed to explore mechanisms underlying these effects

142 However, further work is needed to explore the relationship between dissociati

143 Further research is needed to externally validate these predictive equati

144 We argue that such approaches are needed to fine tune the relevant features necessary

145 nomic consequences, and urgent interventions are needed to flatten the curve of HF in South Asia.

146 fibrils because adenosine triphosphate (ATP) is needed to fuel sarcomere shortening.

147 means that rigorous case-by-case assessments are needed to fully comprehend the consequences of MRED

148 Continued investigations are needed to fully elucidate the landscape of germline

149 that more than two nights of recovery sleep are needed to fully restore memory function and hippocam

150 tiple biomedical and engineering fields will be needed to fully realize the promise of OoCs for funda

151 evolution within thrips, extensive sampling is needed to fully understand these phenomena across the

152 Targeted longitudinal studies are needed to further characterize prognostic factors in

153 ccines aiming to reduce infection incidence, are needed to further decrease exposures occurring in 'n

154 tential, although larger prospective studies are needed to further evaluate possible enhancements to

155 inical failure; however, prospective studies are needed to further evaluate the effectiveness of shor

156 Studies are needed to further understand the thrombotic complica

157 on of USA300 MRSA BSIs in the community will be needed to further reduce burden from MRSA BSIs.

158 o the corona, and this specific pool of MAD1 is needed to generate a robust SAC response.

159 patients with clinical indicators of sepsis are needed to guide measures to safely reduce antimicrob

160 hemolytic uremic syndrome (HUS) risk factors is needed to guide care.

161 Further studies are needed to identify and validate robust biomarkers in

162 es of large cohorts with diverse populations are needed to identify epidemiologic and molecular facto

163 Automated signal detectors and classifiers are needed to identify events within these datasets, suc

164 all fraction of SCZ risk, and larger samples are needed to identify individual risk genes, as coding

165 Yet, molecular studies are needed to identify loci accounting for genetic herit

166 Biomarkers are needed to identify patients at risk for development

167 Complementary measurements are needed to identify the best conditions and timescale

168 es, simple, widely available screening tests are needed to identify which individuals, who are experi

169 More definitive treatment trials will be needed to identify optimal treatment strategies for i

170 Further research is needed to identify bottlenecks and evaluate intervent

171 Further study of local transmission networks is needed to identify drivers of transmission.

172 Further research is needed to identify effective treatments for acute hea

173 Further work is needed to identify improved interventions for both th

174 More research is needed to identify the bacterial factors involved in

175 More work is needed to identify the conditions that promote effect

176 of substrate selectivity by SMR transporters is needed to identify the types of selective pressures t

177 f patients with nonalcoholic steatohepatitis are needed to improve patient outcomes, including direct

178 New drugs or combinations are needed to improve patient therapy and to enhance the

179 melanoma; however, new treatment strategies are needed to improve patients' outcomes(1,2).

180 Further work may be needed to improve TSTin3D's calibration.

181 ith COVID-19 are scarce, increased reporting is needed to improve our understanding of COVID-19 and t

182 Research on the required duration of TaNT is needed to improve the affordability assessment, and m

183 ous, relevant, and ethical clinical research is needed to improve the care and optimize outcomes for

184 Further refinement of culture media is needed to improve the quality of embryos generated in

185 cell via ACE2 that next to its role in RAAS is needed to inactivate des-Arg9 bradykinin, the potent

186 gest that both advocacy and systems training are needed to increase actual LDKT rates, and that LDN p

187 and analysis for the cost of healthier foods are needed to inform both local interventions and system

188 coronavirus 2 (SARS-CoV-2) serologic assays are needed to inform diagnostic, therapeutic, and public

189 of clonal evolution, and prospective trials are needed to inform effective prevention and treatment

190 tional estimates for this group of pathogens are needed to inform public health action.

191 stimated, and data from low-income countries are needed to inform the public health response.

192 s a growing concern, and evidence-based data are needed to inform treatment options.

193 ity and feasibility considerations will also be needed to inform decision making.

194 , risk factors, and timing of CNS metastasis is needed to inform surveillance strategies for patients

195 o advanced signal processing techniques that are needed to interpret the coded sensor outputs.

196 Future trials are needed to investigate potential benefits of producin

197 Further studies are needed to investigate the molecular mechanism and ov

198 Further studies are needed to investigate the relationship between objec

199 Further research is needed to investigate the link between presenteeism,

200 New storage technologies are needed to keep up with the global demands of data ge

201 Actions are needed to limit the incidence of, and to effectively

202 also identify areas of future research that are needed to link and verify these pathways to enhance

203 d fishes and tetrapods), in which Pax6 would be needed to maintain specific entities of subpopulation

204 ter sample sizes and cell-type specific data are needed to map all GWAS loci.

205 it has been proposed that cognitive control is needed to mediate this conflict between reward and ou

206 T1 expression in oligodendrocytes and myelin is needed to metabolically support axonal function, the

207 Lead structure optimization is needed to minimize the percentage of A9 unspecific bi

208 ructures for clinician mental health support are needed to mitigate the psychological costs of provid

209 ovements and leaflet modification strategies are needed to mitigate the risk of coronary obstruction

210 e (CO(2)) in deep geological saline aquifers is needed to mitigate global greenhouse gas emissions; m

211 ggest that greater public health efforts may be needed to mobilize the most vulnerable communities.

212 Improved methods are needed to model CRISPR screen data for interrogation

213 Accurate estimates of seroprevalence are needed to model transmission dynamics and estimate m

214 Predictive, noninvasive tools are needed to monitor key features of nonalcoholic fatty

215 Future translational studies are needed to more fully understand the neural mechanism

216 Additional studies are needed to more precisely delineate the best strategi

217 icroscopy (TEM), but higher-resolution tools are needed to observe more subtle structural differences

218 iciency virus (HIV) drug resistance profiles are needed to optimize individual patient management and

219 vestigation and stronger national guidelines are needed to optimize patient selection for colectomy.

220 Dedicated expertise is needed to optimize outcomes for this population.

221 ement, and additional therapeutic modalities are needed to overcome this deficiency.

222 Further research is needed to overcome potential restrictions for IVT in

223 nd chemical tools, we demonstrated that FACT is needed to overcome replication stress.

224 Sequence-based methods are needed to predict pretreatment variants' neutralizat

225 Therefore, novel strategies are needed to prevent clinical events through mechanisms

226 se policies, and rigorous impact assessments are needed to prevent severe biodiversity losses from ru

227 ises and discuss the interventions that will be needed to prevent widespread extinction in this group

228 An improved understanding is needed to prioritize prevention, including vaccinatio

229 a detailed representation of the task, which is needed to produce a sustained conditioned physiologic

230 A large population-based prospective study is needed to produce representative longitudinal referen

231 h tumors, single-nucleus RNA-Seq (snRNA-Seq) is needed to profile frozen or hard-to-dissociate tumors

232 ccounting guidance and governance frameworks are needed to prompt climate action.

233 Significantly more information is needed to provide a strong scientific basis for modif

234 ognosis is an ethical mandate, more research is needed to provide an evidence base for teaching and p

235 of two insulin substitutions, A14E and B25H, was needed to provide increased stability toward proteol

236 se of CRISPR-Cas9-based genetics, approaches are needed to quantify a specific, molecular phenotype a

237 rt ongoing reforms in Queensland's fisheries is needed to quantitatively link reef degradation to sto

238 rganic semiconductor and the drain electrode is needed to reach a full understanding of Organic Elect

239 tally, and further technological innovations are needed to reduce capital and energy costs in such fa

240 tors and improved acute treatment strategies are needed to reduce disparities in post-MI outcomes.

241 Concerted efforts are needed to reduce health inequalities that are due to

242 ong-term survival advantage, so more efforts are needed to reduce reinfection risks for PWID.

243 ction tools as part of routine clinical care are needed to reduce the impact of the disease on the ba

244 s to secondary prevention of stroke in China are needed to reduce these risks.

245 In Analysis 1, high POCT sensitivity was needed to reduce the chlamydia-associated burden.

246 Further research is needed to refine strategies that may perhaps improve

247 Interventions are needed to reinforce awareness that pulmonary vasodil

248 derstanding of plant photosynthetic response is needed to reliably predict changes in terrestrial car

249 Further research is needed to replicate these findings and assess long-te

250 We find that a single gene, Hairy (H), which is needed to repress trichome fate, underlies variation

251 show that WAPL-dependent cohesin removal is needed to restart DNA synthesis at stalled forks and

252 Further studies are needed to reveal the underlying mechanism.

253 Further research is needed to reveal the nature of these relationships be

254 thus, a fast, simple and reliable biosensor is needed to routinely determine the UA concentration in

255 vely little about the hiring process or what is needed to secure a job offer.

256 Complementary neural mechanisms are needed to sometimes ignore repetitive stimuli (e.g.,

257 A better biological understanding of AF is needed to spearhead novel therapeutic avenues.

258 information, complex community-like systems are needed to study the properties of oral communities.

259 Such frameworks are needed to support evidence-based decision-making.

260 Further replication and functional studies are needed to support our findings.

261 More large, well-designed multicentre trials are needed to support the conclusion of this study.

262 th patient gene expression and drug response is needed to support future work of machine learning mod

263 Improved methods are needed to systematically map RNA-protein interaction

264 Large community-based studies are needed to test its validity and predictive capabilit

265 Further studies are needed to test the intermittent fasting from dawn to

266 Such knowledge is needed to thwart serious threats to human health and

267 ry of spirochetes, further optimization will be needed to translate this strategy for diagnosis of Ly

268 Inhibitors of muscle myosin ATPases are needed to treat conditions that could be improved by

269 olution are common and costly, interventions are needed to treat distressed couples and to prevent di

270 Rational new strategies are needed to treat tumors resistant to kinase inhibitor

271 on of the in-place response, less pull force was needed to trigger a step when visual velocity appear

272 More trial emulations are needed to understand how often and in what contexts

273 Additional studies are needed to understand the cellular mechanisms underly

274 Further studies are needed to understand the differences between guideli

275 Further studies are needed to understand the mechanisms underlying these

276 nfections is controversial, and more studies are needed to understand their orchestration.

277 Further research may be needed to understand optimal device choice for these

278 Further research is needed to understand care engagement disparities.

279 of contribution of motor actions to sensing is needed to understand even seemingly simple behaviors.

280 ffordability assessment, and more experience is needed to understand how to implement TaNT optimally.

281 Research is needed to understand how to monitor immune response t

282 location within an infected organ or animal is needed to understand localized inflammatory responses

283 Further research is needed to understand the clinical importance of the f

284 However, further research is needed to understand the clinical importance of the o

285 However, further research is needed to understand the clinical value of such testi

286 Finally, we describe where further research is needed to understand the ecology and evolution of vir

287 larger study populations in diverse settings is needed to understand the effect on additional patient

288 Further research is needed to understand the effects of early diagnosis a

289 Further research is needed to understand the generalizability of the find

290 Additional research is needed to understand the implications of these result

291 Further research is needed to understand the intersection between major s

292 Further research is needed to understand the source of these associations

293 search and assessment of potential mediators is needed to understand this relationship.

294 However, a critical eye is needed to understand whether an analogy like this one

295 inhibit HMG-CoA reductase; further research is needed to understand whether there is a similar assoc

296 Further study is needed to understand which measurements best reflect

297 More work is needed to unveil the ecological mechanisms behind tem

298 More long-term studies are needed to upscale this first NLCB estimate to less p

299 ge acquisition and analysis, further studies are needed to validate this method in clinical practice.

300 al proteome, though future experimental work is needed to validate our model assumptions and findings