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1 processes identified by molecular biology to be of importance.
2 oendocrine and immunologic abnormalities may be of importance.
3 inophil survival and mediator generation may be of importance.
4 on initial surgery to the primary tumor may be of importance.
5 s, membrane ERalpha (mERalpha) signaling may be of importance.
6 sources which result from farming activities is of importance.
7 ion of neurons and their axonal trajectories is of importance.
8 nes, the functional protomeric state of LRAT is of importance.
9 vitro detection of acid ceramidase activity is of importance.
10 g the experiments with a precision below 1 K is of importance.
11 ce, the study of plant pathogen interactions is of importance.
12 production method under ambient environment is of importance.
13 scription factors regulate cellular outcomes is of importance.
14 stribution and segregation in complex alloys is of importance.
15 d identification of its downstream molecules are of importance.
16 Methods to curtail radiation dose are of importance.
17 ticularly in defining which receptor subtype is of importance and in identifying a possible mechanism
18 further advance the view that this site may be of importance as a target in some human neuropathies.
19 transmitters work after specific lesions may be of importance as an animal model of Alzheimer's disea
24 Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researchin
26 c patterns in the timing of the onset of AMI is of importance because it implies that there are trigg
27 '-tetraacetic acid-Lym-1 (90Y-21T-BAD-Lym-1) is of importance because of its potential for radioimmun
28 state of G-protein-coupled receptors (GPCRs) is of importance because they mediate most of our physio
29 racellular vesicles (EVs), such as exosomes, is of importance both in the context of understanding th
31 ir role in antigen-specific immune responses is of importance, but their role in disease protection i
32 decrease in T-cell activation, effects which are of importance during the initial phase of infection.
35 t cellular proliferation, an effect that may be of importance during malignant transformation as well
37 r distension were small and seem unlikely to be of importance except perhaps during abnormal ventricu
38 1 to -5 have distinct characteristics, which are of importance for a greater understanding of botulis
39 ases cleave proteins at proline residues and are of importance for cancer, neurological function, and
42 bit coupling and intrinsic symmetry breaking are of importance for fundamental physics and device app
48 Y335F) and the active-site interactions that are of importance for the enzyme's function are discusse
50 n with a variety of photophysical properties are of importance for the fundamental understanding of t
54 med cells with the surrounding stromal cells are of importance for tumor progression and metastasis.
59 advantages over the discontinuous assay will be of importance for both the kinetic characterization o
60 urally similar to MKS1 and has been shown to be of importance for ciliogenesis in Caenorhabditis eleg
61 e isoform differences, and the results might be of importance for designing tissue-specific analogs o
62 mmune infiltration and activation could thus be of importance for diagnosis and evaluation of treatme
64 9p23-p22.3 (NFIB) and 22q12-qter (PDGFB) may be of importance for disease progression in a subset of
65 components of the pneumococcal NP flora will be of importance for evaluation of the impact of interve
66 gical reagent compartments will, in general, be of importance for future analytical test systems on m
67 ctive regarding ecosystem function that will be of importance for future environmental management and
70 enhance the relevance of this model and will be of importance for identifying compounds that inhibit
76 TG), which led us to speculate that it could be of importance for regulating alpha1-tubulin gene tran
77 tures adopted by the PSMalpha peptides could be of importance for S. aureus virulence and might facil
78 bitor of p53-induced senescence, which might be of importance for skin tumor formation and cellular a
79 methods involving hyperpolarized water could be of importance for solution-state biophysical investig
80 of active auditory nerve fibers, which will be of importance for the development of treatments for a
81 ng atoms rather than pi-conjugation seems to be of importance for the enzyme-catalyzed, redox-coupled
82 DNA vaccines against established tumors will be of importance for the further development of multiepi
84 YP27A1 as an antibreast cancer target, could be of importance for the interpretation of Femara versus
85 h proportion of CR+ interneurons, what might be of importance for the presumed gating function of PRC
87 es a plasticity in the adult retina that may be of importance for the recovery of vision in human pat
88 e starch degradation in kiwifruit, which may be of importance for the storage and eating quality of t
89 cell transplantation with gene therapy could be of importance for the treatment of acute myocardial i
90 ion during necrosis and apoptosis, which may be of importance for the understanding of cell death and
93 se novel and generic correlation models will be of importance for WRRF operators to reduce operationa
96 rs with arbitrarily complex plasmonic arrays is of importance for a variety of applications in optica
98 dification and large-scale cloning of cattle is of importance for agriculture, biotechnology, and hum
99 e complex structural variations in DNA which is of importance for both research and clinical diagnost
101 igure-8 reentrant circuits (ie, the isthmus) is of importance for catheter ablation to stop reentrant
104 of CRAM from the ER, while the second domain is of importance for confining CRAM to the flagellar poc
105 This "zero premature release" characteristic is of importance for delivery of toxic drugs in chemothe
106 BD3, CHD4, and HDAC1 among other components, is of importance for development and cancer progression.
107 ition and photoelimination of bromine, which is of importance for energy storage reactions involving
108 ailed characterization of their binding mode is of importance for further development of VAP-1 inhibi
111 es associated with pathogenic microorganisms is of importance for improving vaccine design, especiall
112 phenomenon, known as interstitial exclusion, is of importance for interstitial fluid volume regulatio
113 lity to drive reactivity using visible light is of importance for many disciplines of chemistry and h
114 l variance in the metabolic phenotype, which is of importance for molecular epidemiology study design
117 fluence stress-induced dopaminergic function is of importance for pathological states where dopamine
119 ptides to elicit CD8 T cell responses, which is of importance for rational T cell vaccine design.
122 ttern surfaces on a microscopic length scale is of importance for technological applications such as
123 ing MPER epitope on HIV virions, and as such is of importance for the design of therapeutic intervent
126 flow-weighted dual-input time-activity curve is of importance for the estimation of hepatic blood per
127 growing organisms, whereas spatial structure is of importance for the evolution of high-yield strateg
128 new types of two-dimensional (2D) monolayer is of importance for the fabrication of next generation
129 a proximal GAS site at the IL-18BP promoter is of importance for the functional activity of IL-27.
130 hat an SGLT2i-induced glucagonotropic effect is of importance for the glucose-lowering property of SG
131 ength of the Earth's early geomagnetic field is of importance for understanding the evolution of the
132 fferentiating between B. avium and B. hinzii is of importance for veterinary diagnostic laboratories.
134 ervoirs by biological and physical processes was of importance for this biodiversity crisis, but the
138 n of foods that are higher in nutrients that are of importance in adolescence and lower in energy den
142 teractions of two-dimensional (2D) materials are of importance in developing flexible electronic devi
143 -alpha, and IL-12 in myeloid dendritic cells are of importance in generating T helper-1 biased adapti
147 bes (BNNTs) in high temperature environments are of importance in pursuit of their applications that
149 spectra for multinuclear Mn complexes, which are of importance in several metalloenzymes; one of them
150 tissue from patients with MS, these findings are of importance in the development of approaches to tr
151 onic coupling between the conjugate moieties are of importance in the interfacial electron-transfer d
153 The presence of variant ERs and PRs may be of importance in altering the physiological effects o
154 nesis in the respiratory epithelium that may be of importance in assessing individuals for risk of a
156 an alpha-amino acid bioisostere, which could be of importance in bioisosteric replacement strategies
157 lobally stable DNA conformational states can be of importance in biological regulatory mechanisms.
158 circadian timekeeping, and such effects may be of importance in both the therapeutic and side effect
159 have distinct enzymatic properties that may be of importance in carrying out their cellular function
161 preserve liver cell binding function and may be of importance in designing anti-sporozoite vaccines.
162 exposed, creation of the intermediate could be of importance in drug and/or vaccine development.
166 common in macrophage and fusion hybrids may be of importance in identifying the regulatory factor(s)
167 , has multiple biological functions that may be of importance in inflammation and in the pathogenesis
168 DNA analysis indicate that this approach may be of importance in investigating common ancestry in oth
170 didate on the X chromosome, Xlr3b, which may be of importance in mediating the behavioral effects.
171 s characterized by glutathione depletion may be of importance in mediating the progression from mild
172 alpha expression by glucocorticoids seems to be of importance in monocytes and lymphocytes, it cannot
173 Infliximab-based therapy could, thus, still be of importance in multiple chronic liver disorders tha
174 ivation, and tube formation and is likely to be of importance in myocardial angiogenesis in vivo afte
178 etween this residue and the vinyl groups may be of importance in regulating the heme redox potential
180 mpound under aerobic conditions is likely to be of importance in similar biological processes where a
182 rs (ADORs) in the enteric nervous system may be of importance in the control of motor and secretomoto
184 major route of entry for paromomycin and may be of importance in the design and discovery of novel dr
186 ently aberrated regions, which are likely to be of importance in the development and progression of C
187 iabetes and cardiovascular disease, may also be of importance in the development and progression of s
188 le, efficient, and cost-effective and should be of importance in the development of biosensors based
189 response to supramaximal CER stimulation may be of importance in the early pathogenesis of acute panc
190 sible that NY-ESO-1, TRP-2, and TRP-2-6b may be of importance in the generation of CTL-mediated tumor
191 FN-dependent induction of two genes known to be of importance in the generation of IFN responses, Isg
192 distinct from that of GP IIb/IIIa, which may be of importance in the initiation of thrombosis associa
194 an and experimental tumors and is thought to be of importance in the local host defense response.
195 These findings suggest that c-ets-1 may be of importance in the mitogenic signaling pathway of s
196 ts expression by pancreatic cancer cells may be of importance in the pathobiology of this disorder.
197 imbing fibre-Purkinje cell connections could be of importance in the pathogenesis of essential tremor
198 in particular its thickness, are believed to be of importance in the pathophysiology of a number of r
199 These findings suggest that BP control may be of importance in the prevention of mitral regurgitati
200 ing the balance between these two events may be of importance in the prevention of tubular injury ass
201 ater consumption of total dairy products may be of importance in the prevention of weight gain in mid
202 suggests that the CD40L-CD40 interaction may be of importance in the priming of T helper (Th) 1-type
203 strategies used by newly isolated phages may be of importance in their consideration for various appl
205 actors, including genetic mutations that may be of importance in triggering recurrence and progressio
206 strocytes occurs in AIDS, a finding that may be of importance in understanding HIV neuropathogenesis.
207 ic to the eye of the Cln3-knockout mouse may be of importance in understanding the function of CLN3 i
208 function, and downstream targets are likely be of importance in understanding the mechanisms underly
213 plementary motor area (SMA) of the cortex as being of importance in implicit learning, we here explor
214 articular the CATT(7)-MIF-173(*)C haplotype, being of importance in susceptibility to psoriasis.
215 micrometre- and submicrometre-scale patterns is of importance in a range of applications, such as pho
217 ith precise chemistries on material surfaces is of importance in a wide variety of areas such as lith
219 alylation linkages at the glycopeptide level is of importance in bottom-up glycoproteomics and an ind
220 he enzymatic hydrolysis of alpha-L-fucosides is of importance in cancer, bacterial infections, and fu
221 he absence of other adenoviral gene products is of importance in delineating the adenovirus-host cell
223 anism(s) underlying immunosuppression of HIV is of importance in guiding therapeutic and vaccine-rela
224 nism(s), most likely bacterial opsonization, is of importance in localizing anaerobic root canal infe
225 nisotropic particles through narrow channels is of importance in many fields, ranging from the spinni
226 vivo, which can be studied in mouse models, is of importance in obtaining information on immune resp
227 nsible for specific cognitive processes, and is of importance in planning resections close to eloquen
228 ses of systemic and topical corticosteroids, is of importance in preventing ocular complications, suc
229 that the structure of the thiosemicarbazone is of importance in terms of metHb generation, because t
231 genetic variation not explained by major QTL is of importance in the complete dissection of quantitat
232 other sequence-specific DNA binding proteins is of importance in the consideration of mechanisms of t
233 lls, its abundant expression in Muller cells is of importance in the handling of glutamine in the ret
235 receptor family, pyrin domain containing 3) is of importance in the pathogenesis of CVB3-induced myo
237 Biotransformation of chemical contaminants is of importance in various natural and engineered syste
239 ion of LMP2A protein expression in HD and IM is of importance in view of the proposed role of this pr
240 1 infection, but definitive evidence that it is of importance in virus containment has been lacking.
241 enetic variation in drug metabolism pathways is of importance not only in livestock, but also in huma
242 s for which the stability of surface bubbles is of importance, such as bio-foams, froth floatation, a
246 ures, the recognition and treatment of which are of importance to general neurological practice.
249 Genome scans for feed efficiency traits are of importance to reveal the underlying biological ca
252 proliferate inside artificial materials and are of importance to the field of tissue engineering.
255 enic potential of each Lactobacillus sp. can be of importance to both clinical microbiology and the f
260 s from molecular displacements and these may be of importance to photosynthetic energy transfer.
261 oxygen-driven tuning of the Agr system might be of importance to provide the pathogen with capabiliti
262 h of the reactants (H and C2Hx) was found to be of importance to the energetics of the reaction.
267 rfaces that promote rapid drop detachment1,2 is of importance to a wide range of applications includi
268 These findings indicate that MUC1-C function is of importance to AML cell self-renewal and that inhib
269 ate catalase and that this signaling pathway is of importance to apoptosis in the oxidative stress re
271 ocarbons (PAHs) in ambient aerosol particles is of importance to both human health and climate forcin
272 of diverse sp(3) -rich skeletal ring systems is of importance to drug discovery programmes and natura
273 rmination of trypsin inhibitor (TI) activity is of importance to evaluate the nutritional value of so
275 or anergy of self-reactive lymphocyte clones is of importance to immunization against tumor-associate
276 n during the analysis of biological data, it is of importance to interpret the correlation structure
278 cological function of the produced compounds is of importance to reveal functional interactions in mi
279 jor crop plant potato (Solanum tuberosum L.) is of importance to secure yield even under changing env
281 stabilizes ERalpha and that this oncoprotein is of importance to the activation of ERalpha function.
285 Aerobic biodegradation of naphthenic acids is of importance to the oil industry for the long-term m
287 grow in the near-surface environment of Mars is of importance to the search for life and protection o
288 e effects that oxidative lesions have on RNA is of importance to understand their role in the develop
289 eases during systemic inflammation, hence it is of importance to understand whether LDL-derived ceram
290 cts the role of albumin as a distributor, it is of importance to unravel the structural mechanism tha
291 hat binds covalently to proteins and DNA, it was of importance to identify the P450(s) catalyzing its
293 fficiency under physiological conditions may be of importance when alpha-synuclein undergoes the misf
297 understanding of this epimerization process is of importance when Pictet-Spengler reactions are carr
298 for MDL formation during myelination, which is of importance when understanding myelin assembly and