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1 MC is mandatory for appropriate treatment to be rendered.
2 c community, so that prompt intervention may be rendered.
5 he protonated monocarboxylic form, succinate is rendered a transport substrate for monocarboxylate tr
6 w how enhancers of macrophage-specific genes are rendered accessible in differentiating macrophages t
7 r, the final three nucleotides of the genome are rendered accessible to the RNA-dependent RNA polymer
8 istence of labile assembly machines that can be rendered accessible as next-generation drug targets b
10 Here, we show that hydrophobic P4 molecules are rendered air-stable and water-soluble within the hyd
13 ls activated in the absence of costimulation are rendered anergic and are hyporesponsive when present
14 igens are present with low frequency and may be rendered anergic by the tumors that express them, we
15 the catalytic activity of a light chain can be rendered antigen-specific by pairing with a noncovale
16 on CD95 is frequently downregulated or cells are rendered apoptosis resistant, raising the possibilit
17 resistant to TNFalpha-induced apoptosis but are rendered apoptosis-sensitive on coculture with strom
22 te vector-based drawings and scenes that can be rendered as raster-graphics images, allowing for easy
26 e critically considered, and overall opinion is rendered based on the available peer-reviewed literat
28 e T cells is selected in the thymus where it is rendered both self-tolerant and restricted to the rec
29 ully mismatched lung grafts from donors that were rendered brain dead and mechanically ventilated for
30 Following each bump, individual microvilli are rendered briefly (~100-200 ms) refractory, thereby r
31 hat the smooth, regular, structures produced are rendered by highly dynamic supramolecular transforma
32 , respectively, whereas enzymatic inhibition was rendered by a potent second-generation small molecul
33 ly constitutes a key step in exocytosis that is rendered Ca(2+)-dependent by interactions with synapt
36 lamino)pyridine (DMAP) and benzoic anhydride are rendered chiral via interaction with a chiral thiour
38 acoresistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe
40 s of in vitro aggregation of alpha-synuclein are rendered complex because of the formation of a heter
41 owth phase-dependent even when transcription is rendered constitutive, suggesting additional posttran
43 kinase is an important cellular enzyme that is rendered constitutively active in the breakpoint clus
44 required for LRT persistence even when BvgAS is rendered constitutively active, suggesting the presen
45 synapse from mutant mice in which syntaxin-1 is rendered constitutively open and SNARE-complex assemb
48 r-driven NF-kappaB activity (CARMA1-KO mice) were rendered diabetic and transplanted with islet allog
55 AND Cav1 knockout and wild-type C57BL/6 mice were rendered diabetic with streptozotocin, and changes
58 e expression of a glutamate-terminal protein is rendered difficult because the N-terminal methionine
60 as been broadly implicated in longevity, but is rendered dispensable for rIIS lifespan extension by e
61 findings suggest that the basement membrane is rendered distensible by proteolytic degradation to al
64 the discovery of key cellular pathways that are rendered dysfunctional during cancer progression.
65 ct DNA repair pathways depending on how they are rendered dysfunctional, and that A-NHEJ is a major p
66 fection, plasmacytoid dendritic cells (pDCs) are rendered dysfunctional, as measured by their decreas
67 x (PFC) involved in emotional processing may be rendered dysfunctional by chronic exposure to delta-9
69 stant to extinction, but extinction training was rendered effective when the training was combined wi
70 periments, we show that Cas12a orthologs can be rendered either sensitive or resistant to AcrVA4 thro
72 roatom, which is typically nucleophilic, has been rendered electrophilic by changes to the oxidation
73 st that many processes that rely on SmI2 can be rendered enantioselective by the design of suitable l
75 of appropriate chiral ligands, this reaction is rendered enantioselective and applies to both aromati
77 WT) control, TxNIP(-/-), and TxNIP(+/-) mice were rendered equally diabetic with low-dose streptozoto
78 picture of alcoholic end-stage liver disease is rendered extremely complex, as manifestations such as
81 netic field enhancement of charge order that is rendered fragile in zero magnetic fields because of i
83 llular rejection at the time of testing that is rendered from a single ordinal gene-expression profil
84 llular rejection at the time of testing that is rendered from a single ordinal gene-expression profil
87 accessibility when PDZ2 is occupied, and can be rendered functional in vivo by additional mutation of
88 that the process of CD8(+) T cell activation is rendered fundamentally different by early life AHR si
90 tor conjugate, in which the insulin molecule is rendered glucose-responsive via conjugation to an inh
94 t the genome except at the test locus, which is rendered hemizygous for alternative alleles from the
95 PdCl(2) catalysts without requiring them to be rendered heterogeneous, the addition of exogenous lig
97 inistic control of ferroelastic domains that are rendered highly mobile in a controlled and reversibl
98 ia a simple two-step synthesis, the pigments are rendered highly soluble in organic solvents and in p
99 We show herein that stapled peptides can be rendered highly cell-permeable by conjugating a cycli
101 ramics, which are generally hydrophilic, can be rendered hydrophobic by polymeric modifiers, these de
102 erties of CB[7], the inner cavity of MOP can be rendered hydrophobic by using octadecyl HDA (3) as gu
104 oxO1 (L-FoxO1) and their control littermates were rendered hyperglycemic by streptozotocin administra
106 bryonic Ag expressed by a variety of tumors, is rendered immunogenic if targeted to the APCs using th
109 ostate biopsies stained with acridine orange are rendered in seconds and contain excellent contrast a
111 is normally in a nucleosome-depleted region, is rendered inaccessible by altered nucleosome positioni
112 no experimental information is included but were rendered inaccurate by the SHAPE data of Das and co
117 itutively active dimer conformer of PDK1 may be rendered inactive by small molecules that drive it to
119 eveloping new plasmids in which the pBt gene is rendered inactive after excision of the transposon fr
122 unable to achieve the fully closed state and is rendered inactive despite possessing all of the resid
125 ing in a subset of CRPC tumors as the AR-LBD is rendered inactive, suggesting an important mechanism
129 vely acid-stable hemagglutinin (HA) proteins are rendered incapable of pH-induced triggering for memb
130 proton channel, the mechanisms by which they are rendered ineffective against M2S31N are unclear.
133 s those that match their backgrounds [5, 6], are rendered ineffective once prey are moving [7-10].
134 examples in which small molecule inhibitors are rendered ineffective when their kinase targets are i
135 circumvent known resistance mechanisms, can be rendered ineffective by unrecognised adaptations in t
139 paired by sediment infilling, croplands will be rendered infertile by salt, and water scarcity will p
140 lt and 5 prepubertal recipient macaques that were rendered infertile with alkylating chemotherapy.
142 Viruses inhibited by pseudoknot aptamers were rendered insensitive by a naturally occurring R277K
143 H)(2)D(3) in control cells, almost all (113) were rendered insensitive to the hormone in VDRE-BP-over
147 use xenograft models of human glioma and can be rendered into three-dimensional images offering exqui
148 ns of maturing animals of several species to be rendered into vellum of equal quality and fineness.
149 on binding to fibrillin-1, the BMP-7 complex is rendered into a closed ring shape, which also confers
150 t existing genome browsers, where the genome is rendered into images on the webserver and the role of
151 isual synchrony even when the visual stimuli are rendered invisible through interocular masking.
152 ssion, a suprathreshold monocular target can be rendered invisible by a salient competitor stimulus p
154 A testing stimulus presented to one eye was rendered invisible by a masking stimulus presented t
157 versions in which the hierarchical structure was rendered irregular whereas the local structure was k
158 r, the VAT-Claisen reaction described herein is rendered irreversible by C-C bond cleavage, not by de
162 l medicines discovered in a cellular screen, are rendered less active by mutations in a parasite P-ty
164 ch as artemisinin combination therapies have been rendered less effective due to developing parasite
166 ls; toddlers failed when these trials either were rendered less effective or were used in a high-inhi
167 ped with dideoxy termini, whereas 3'-PG ends were rendered ligatable, linked to an anchor, and quanti
168 ue clearing in which whole organs and bodies are rendered macromolecule-permeable and optically trans
170 rs are crystallographically inequivalent but are rendered magnetically equivalent on the time scale o
172 osome missegregation rates have been reduced are rendered markedly more resistant to IR, exhibiting d
173 found that membrane-permeable bioagents can be rendered membrane impermeable by covalent attachment
174 east cancer cells with the inhibitors, which were rendered membrane permeable by attachment of an oct
180 cate that several transient Env epitopes can be rendered more accessible to antibodies (Abs) via spec
181 as "carbohydrate-like" behaviour may need to be rendered more flexible, at least as far as interactio
183 is either native to both continents but has been rendered more pathogenic in North America by mutati
185 upon restoration of extracellular Ca(2+) but were rendered more sustained by the PLC inhibitors.
187 with high molecular weight DNA, SNM1A alone is rendered much more active, being capable of digesting
188 when molecular- and activity-dependent cues are rendered nearly equal in force, they drive topograph
189 markably unaffected when starburst dendrites are rendered non-directional, using a novel strategy com
190 rtance of the Ugt1 locus in mice, this locus was rendered non-functional by interrupting exon 4 to cr
192 whereas transport of other active components was rendered nonessential either by their high fibrin-bi
193 the related receptor EF-Tu receptor that can be rendered nonfunctional by disruption of single glycos
194 Here we show that both Mx1 and Mx2 have been rendered nonfunctional in Odontoceti cetaceans (too
195 ed homologue for wild-type human p53 protein is rendered nonfunctional by cytoplasmic sequestration.
196 ex that facilitates miRNA-mediated silencing is rendered nonfunctional during cellular stress, includ
199 rived from host plasma membrane, the vacuole is rendered nonfusogenic with the host endolysosomal sys
202 transgenic mice where Ser22/23 in cTnI have been rendered nonphosphorylatable by mutation to alanine
207 Streptozotocin-induced diabetic FVB/NJ mice were rendered normoglycemic with a therapeutic mass of s
208 s were isolated from EP4(flox/flox) mice and were rendered null for the EP4 receptor with adenoCre vi
209 n vivo, Ucp2(DeltaLysM) and Ucp2(fl/fl) mice were rendered obese and insulin resistant through high-f
212 puts to orientation-selective ganglion cells are rendered orientation selective within the presynapti
213 ought to be unrelated to the RF ablation and was rendered pain-free after subsequent surgical treatme
214 attack frequency) was 82% and four patients were rendered pain-free for prolonged periods of time.
215 d dyskinesia, we used D5R knockout mice that were rendered parkinsonian by unilateral 6-OHDA injectio
219 utologous CD4 T cells in which the CCR5 gene was rendered permanently dysfunctional by a zinc-finger
220 ically the two catecholaminergic groups, can be rendered persistently impaired after long-term exposu
222 rget areas of tissues or organisms that have been rendered photosensitive by genetic targeting of ChR
223 e nail material adjacent to the ablated area was rendered porous in appearance presumably due to loca
224 utionizing recovery via sub-solvus annealing is rendered possible by the rafting (i.e., directional c
226 ating-exposure conformational cycle that has been rendered proton-independent by the gate mutations.
227 ctively downregulated and that the cells had been rendered refractory to subsequent in vivo Ag contac
228 nors carry a KDPI over 35 and have therefore been rendered relatively inaccessible to pediatric recip
229 table metastatic colorectal cancer (CRC) can be rendered resectable with systemic chemotherapy in app
230 Free RGS18 levels also rise when platelets are rendered resistant to activation by exposure to pros
231 not mediate graft-versus-host reactions and are rendered resistant to destruction by alemtuzumab.
238 on was significantly greater in patients who were rendered seizure-free, suggesting that a smaller re
240 novel lentiviral vectors (CD4-LV) that have been rendered selective for human or simian CD4(+) cells
241 iodide was used as an additive, the reaction was rendered selective for dimer formation (dimer/trimer
245 variations in the gap gene expression, which is rendered sensitive to the geometry of the embryo unde
246 ly occurring, pseudoknot-insensitive viruses were rendered sensitive by the inverse K277R mutation, e
247 sistant to treatment with antibodies to VEGF were rendered sensitive in IL-17 receptor (IL-17R)-knock
251 nterface, dozens of ligand-protein complexes are rendered simultaneously to parallelize the analysis
252 nervous system, hundreds of volume channels are rendered simultaneously, whereas fluorescence intens
253 cell (SBC) activity in the Mongolian gerbil is rendered sparser and more reliable by subtractive inh
254 we report that vanadium disulfide flakes can be rendered stable in the electrochemical environment of
255 e show that an initially unstable system can be rendered stable via a reduction in diffusivity-i.e.,
256 tion and Trail Making Test Parts A and B and was rendered statistically nonsignificant by APOE epsilo
258 ST-1 is neutral, coordinated water molecules are rendered sufficiently acidic by Cu(II) to contribute
260 ransformed cells 'addicted' to AP-1 activity are rendered susceptible to SARI-mediated inhibition of
262 as found to be testosterone: male mice could be rendered susceptible to liver inflammation by castrat
263 ths old) and aged mice (22 to 28 months old) were rendered susceptible to C. difficile infection with
264 d immunopathogenesis, WT and MyD88(-/-) mice were rendered susceptible to PcP by depletion of CD4(+)
265 horylation in three-dimensional collagen and were rendered susceptible to PLX4720 by Akt3 knockdown.
269 ated females of the plant bug Lygus hesperus are rendered temporarily unattractive by seminal fluids
270 lated position of a small moving target that was rendered temporarily invisible and whose trajectory
271 ure and empirical knowledge, a super surface was rendered that incorporated the ideal portions from 4
276 e responding cells become fully activated or are rendered tolerant by administration of peptide Ag al
278 h controls a myriad of biological functions, is rendered transcriptionally inactive under hypoxic con
279 (bovine serum albumin, BSA) particles which were rendered transiently insoluble using a novel, reduc
282 e of kidneys with existing tumors, which may be rendered tumor free after surgical excision and recon
284 were abolished when cholangiocarcinoma cells were rendered unable to regenerate cilia by stable trans
288 SF dimer in which binding to the second site is rendered unfavorable by FMS binding at the first site
289 mutated to alanines), in which phospholemman is rendered unphosphorylatable, were used to assess the
290 when intermediate states of gene expression are rendered unstable by the underlying genetic circuitr
292 her this special state of confined water can be rendered useful in chemical processes is hitherto und
293 ng the React and A-Frame frameworks, and can be rendered using commercially available VR headsets or
297 indicate that the cerebral microvasculature is rendered vulnerable to thrombus formation in beta(s)
298 ate; the resulting water-soluble cages could be rendered water-insoluble through reverse anion exchan