ライフサイエンスコーパス: be specific for

1 Oxidation was specific for 11-cis-retinol and 9-cis-retinol.

2 T cell lines were specific for 15 immunodominant peptides and derived

3 HSV-1 glycoprotein B, whereas the other half are specific for 18 subdominant epitopes.

4 This effect is specific for 4-AP compared with its heterocyclic base

5 Both radioligands were specific for 5-HT7R, as binding could be blocked by

6 this protocol, ubiquitinated substrates that are specific for a given ligase can be isolated for mass

7 Vbeta5(+) regulatory T cells (Tregs), which are specific for a mouse endogenous retroviral superanti

8 SSCs, not many definitive markers exist that are specific for a rare subset of SSCs that self-renew a

9 tails that have entered clinical development are specific for a single member of the Ebolavirus genus

10 experimental vaccines and immunotherapeutics are specific for a single member of the Ebolavirus genus

11 a set of lanthanide-tagged antibodies, each being specific for a desired molecular target, quantific

12 y found in serum or cerebrospinal fluid that is specific for a cytosolic intermediate filament protei

13 these demyelinating/axopathic autoantibodies is specific for a subset of patients with multiple scler

14 Each transporter in the APC superfamily is specific for a unique subset of substrates, even if t

15 The test is specific for A-T, independent of the type of ATM muta

16 Two of the MAbs were specific for a hole in the glycan shield of the BG5

17 The 4 new risk loci for AAA seem to be specific for AAA compared with other cardiovascular d

18 gnetic resonance imaging contrast probe that is specific for Abeta oligomers.

19 gagement of Galphaq A representative peptide was specific for active Galphaq because it did not bind

20 1) is a promising blood-based biomarker that is specific for AD, correlates with cerebral Abeta and t

21 AtGALT2 is specific for AGPs because substrates lacking AGP pept

22 (+) T cells in nonimmunized foster pups that are specific for Ags against which the foster dam was im

23 This inhibitory effect is specific for AICD through suppressing NFAT1-regulated

24 can be inhibited by MK2206, a compound that is specific for Akt.

25 cteristic motif at the N-terminus appears to be specific for Al-responsive ALMTs.

26 The probe is specific for ALKBH3 over its related homologue ALKBH2

27 The LC-MS/MS method was specific for all five tested SULTs, whereas Western

28 to direct protein-osmolyte interaction, and is specific for alpha-syn when compared to other neurode

29 While sialic acid binding is specific for alpha2-3-linked sialic acid and mediated

30 s, approximately 0.15% of renal CD4(+) cells were specific for alpha3IV-NC1.

31 These effects were shown to be specific for alpha4beta1 integrin and not other integ

32 This pathway, which is specific for alphavbeta6, because it is not regulated

33 attenuation of lung inflammation during ALI were specific for alveolar-epithelial expressed HIF1A.

34 In C57BL/6J mice, half of these cells are specific for an immunodominant epitope on HSV-1 glyc

35 tate kinetic analysis establishes the enzyme is specific for an intact steroid ring system versus hex

36 This inward vesiculation is specific for AnxA2 and not shared with other PI(4,5)P

37 The effect was specific for ArfGAP3 and dependent on its GAP activi

38 hosphorylated substrates showed that AtPyrP2 is specific for ARPP.

39 permease mutants clearly show that CgAcr3-1 is specific for As(III).

40 EV source with a specific miRNA cargo, which are specific for ASH-related liver injury.

41 While memory guidance is specific for associated facial identities, it does no

42 onserved signature D/E-P motif that seems to be specific for auxin-transporting ABCBs, which we now r

43 TCR transgenic CD4(+) T cell, BthetaOM, that is specific for B. thetaiotaomicron and a complete set o

44 tion of mCD8alpha:chIgalpha-expressing cells was specific for B cells and required active signaling d

45 he future, similar optoacoustic tracers that are specific for beta-cells and combines optoacoustic an

46 This defect was specific for beta1 integrins, as adhesion and polari

47 Furthermore, these inhibitors are specific for beta5i over the other five active subun

48 The imaging findings were found to be specific for bilateral non-gestational pure primary o

49 This domain was specific for binding active, but not latent, TGFbeta

50 The inhibitory activity was specific for blue light, and the inhibiting light wa

51 believe to be modulated by oxytocin, may not be specific for borderline personality disorder but rath

52 ical blood flow with tvortex less than 14.3% was specific for borderline mPAP.

53 However, these binding sites are specific for both cholesterol and beta2AR, as shown

54 hiophene-substituted small molecule GAT1508, is specific for brain-expressed GIRK1/2 channels rather

55 f the GA-inactivating enzyme AtGA2ox2, which is specific for C(19) -GAs, and AtGA2ox7, which acts on

56 lonal antibodies, only two unique antibodies were specific for C-PfCSP, highlighting the rare occurre

57 rences between GLTP superfamily members that are specific for C1P versus glycolipid.

58 did not occur in CA1, suggesting this effect is specific for CA2.

59 eria and features of fusion transcripts that are specific for cancer.

60 -azidopropionylgalactosamine (GalNAzMe) that is specific for cancer-relevant Ser/Thr(O)-linked N-acet

61 Bacterial AlkC and AlkD are specific for cationic alkylated nucleobases and have

62 CCR5 antagonists, Schering-C (SCH-C), which is specific for CCR5, and TAK-779, a dual inhibitor of C

63 The Cas6-1 subtype is specific for CD-family CRISPR repeats, generating crR

64 paragraph of that section; the correct text is "...specific for CD1 and phycoerythrin...".

65 ence of autoantibodies in ICL, some of which are specific for CD4+ T cells, may contribute to pathoge

66 ikingly, the in vivo regulatory role of Gfi1 was specific for CD8(+), and not CD4(+) T cells or immat

67 tion of ACD11, a lipid transfer protein that is specific for ceramide 1-phosphate (C1P) and phyto-C1P

68 DL1, an inhibitory receptor of NK cells that is specific for certain MHC-I allotypes.

69 Anserine was found to be specific for chicken intake, whereas trimethylamine-N

70 nnel in lipid membranes and that the channel is specific for chitooligosaccharides.

71 omponents by size, we found these effects to be specific for cholesterol concentration in medium-size

72 None of the findings are specific for CIDP, meaning that the results of the d

73 ult and none of these demyelinating findings are specific for CIDP.

74 ly 25% of synovial IgG-expressing B cells to be specific for citrullinated autoantigens in the invest

75 Of these residues, Ser-475 and Ser-511 were specific for CKI, whereas the others were shared by

76 the development of precision medicines that are specific for clinical targets.

77 rating that the effects of tat-cyclotraxin-B are specific for cocaine reinforcement.

78 om human butyrylcholinesterase (BChE), which is specific for cocaine hydrolysis, and obtain a much hi

79 m, suggesting that the observed interactions are specific for cognate aa-tRNA substrates, and thus ca

80 antiproliferative effect was demonstrated to be specific for compound 19, endowed with the best combi

81 whole-cell and pure enzymatic assays, and it is specific for cortisol.

82 Of the one third of these transcripts that were specific for CRPC, we defined a novel lncRNA termed

83 PSCu10 is specific for Cu(2+), and it has no cleavage in the pr

84 The resulting assay was specific for d-(+)-maltose versus other sugar analog

85 We concluded that IgE was specific for D-[Asp/Glu], not D-Asp or D-Glu, and th

86 e sensitivity to amino-terminal substitution was specific for DAT, because replacing the SERT N and/o

87 The FISH probes were specific for detection of HMPV positive-sense RNA (

88 r, while the third, which bound less avidly, was specific for determinants at the gp41-gp120 interfac

89 diagnostic laboratory or imaging tests which are specific for diagnosis, they could, however, sometim

90 ther these effects are ubiquitous or if they are specific for different cognitive systems.

91 nomenon, which remain to be clarified, could be specific for different GPCRs.

92 s with bioorthogonal tags that would ideally be specific for distinct glycan subtypes.

93 iquitin conjugates, half of which prefer, or are specific for, DIX54-Ub, including Cezanne and CYLD.

94 Patients' antibodies were found to be specific for DPPX, without reacting with DPP10 or Kv4

95 The sets of HVD-binding host factors are specific for each alphavirus, and we have previously

96 These dynamic responses are specific for each patient and could be responsible f

97 homotypic interactions between epitopes that are specific for each subgroup of patients with homogene

98 hich identifies the two free parameters that are specific for each subject.

99 ches to prevent and treat this disorder that are specific for each type of diabetes.

100 ife course, however, their dynamics seems to be specific for each trait.

101 m-property with a complex genetic basis that is specific for each chromosomal locus, and it can be in

102 is provided in different contexts, learning is specific for each context.

103 onsensus slopes of the calibration lines and is specific for each signal produced by a well-defined s

104 itional value of the cowpeas, but its effect was specific for each cowpea variety.

105 This effect is specific for EGFR versus other Hsp90 client proteins.

106 at observed in the activating complexes, yet is specific for eIF4AIII.

107 eptide-HLA-II complexes, most of the T cells are specific for either of the two epitopes.

108 T cells from the HIV-coinfected cohort that were specific for epitopes of HCMV phosphoprotein-65, te

109 erformed to determine whether tracer binding was specific for ERs.

110 Enwrapment was specific for escaped germ cells, and genetic analysi

111 e sera were seen in IFA but were resolved to be specific for established HCoVs by discriminative test

112 rthologue) as a central assembly factor that is specific for established MKS module components and de

113 ardiac uptake of the PET tracer (18)F-FBzBMS is specific for ET-A expression in rats, shows infarct-r

114 a profound decline in serum antibodies that were specific for exogenous antigen or DNA, frequencies

115 known whether such an interconnected network is specific for faces or whether there are similar netwo

116 enotype of microsatellite signal instability is specific for FANCJ apart from the intact FA pathway,

117 s to be determined whether these alterations are specific for fatigue or whether they relate to other

118 defect is observed in TTD and not in XP and is specific for fibroblasts, which are the main producer

119 the assembly of two zones of actin filaments is specific for fission yeast and not essential for CME.

120 enzymes belong to the UGT family d-clade and are specific for flavonol glycosides and their respectiv

121 The effect is specific for FLT3-mutant cells and is ascribed to the

122 The sensing is specific for fluoride among various other anions.

123 Blocking studies verified that (68)Ga-FOL was specific for FR.

124 lized cargo transport in general rather than being specific for GLUT4.

125 nditions (KD = 2.1-5.7 muM) and that binding is specific for Grb7-SH2 over closely related domains (l

126 ons, 68/69 were confirmed by blotting, which was specific for greater than 275 repeats.

127 ed a synergistic tumor killing activity that was specific for HCC in HBx transgenic mice.

128 The assay is specific for HCV RNA and is free of interference from

129 D) to determine whether any observed changes were specific for HD.

130 us lugdunensis and show that the transporter is specific for heme.

131 This anxiolytic effect was specific for high anxiety as MitoQ treatment did not

132 diatric population, marked hyperferritinemia is specific for HLH.

133 tibody antigen-binding fragments (Fab), that is specific for HT-2 toxin and has a positive readout.

134 8 receptor antagonist domain Abs (dAbs) that are specific for human CD28.

135 fH downregulation of the AP via fHbp or NspA is specific for human fH.

136 t to other Src kinases, and this interaction was specific for human but not mouse proteins.

137 This was specific for IFN-gamma because the inhibitory mutati

138 This enhancement is specific for IL-17A but not for IL-17F, IL-22, and CC

139 Transcriptional silencing was specific for IL-1beta because expression of other pr

140 nclude the development of nanomaterials that are specific for immune cell subsets and can be used as

141 ric and/or cooperative effects as the latter are specific for individual cases only.

142 we have gained into treatment paradigms that are specific for individual phenotypes of achalasia and

143 The emerging parietal representation is specific for individual episodes of experience, predi

144 Inhibition is specific for influenza virus, as inhibition of Sendai

145 rated that the SusC and the MFS transporters are specific for internalization of linear xylo-oligosac

146 This is specific for iTreg development, because frequency of

147 downstream kinase activation by alphavbeta6 is specific for JNK1, with no involvement of p38 or ERK

148 Deletions at 17q12, 4p16.1-p16.3 and 22q11.2 were specific for KA; the 16p11.2 locus showed extensive

149 The imaging findings were found to be specific for Kimura disease.

150 This effect is specific for Kv1.1 because coexpression of Kv1.4 chan

151 The identified conserved complex might be specific for leaf growth in the second dimension, sin

152 the typical type II CHIs currently known to be 'specific' for legume plants.

153 The imaging findings were found to be specific for leiomyomatosis peritonealis disseminata

154 The IKK2-TPL2-JNK axis is specific for LMP1 and differs from TNFalpha, Interleu

155 Interestingly, this pathway is specific for long-day adaptation and appears to be di

156 ly established LTK ligand FAM150A (AUG-beta) is specific for LTK and only weakly binds to ALK.

157 merous autoantigens, and some autoantibodies were specific for lymphocytes.

158 blast transcriptomes encoded antibodies that were specific for major grass pollen allergens and able

159 termining region Y-box 11 (SOX11) expression is specific for mantle cell lymphoma (MCL) as compared w

160 lopment of activating NK cell receptors that are specific for MATp1-modified altered-self MHC I molec

161 This effect is specific for mature miR-221, as it does not affect Pr

162 Here we define a pathway that is specific for METTL3 and is implicated in the maintena

163 bleeds on in vivo magnetic resonance imaging are specific for microhaemorrhages in cerebral amyloid a

164 and diffusion-tensor MR imaging alterations were specific for motor neuron disease phenotypes, with

165 The hydroxamates were specific for MPO in neutrophils and more potent tow

166 ncated peptide (SSTNIGF1R-T) that appears to be specific for multiple myeloma cells.

167 nal patterns for month of birth suggested to be specific for multiple sclerosis (increased in the spr

168 It was confirmed to be specific for Mycobacterium bovis and M.caprae cells.

169 ding evidence that the IatP-IatA transporter is specific for myo-inositol.

170 utination assay (CSF-TPHA) titer of >/=1:640 is specific for neurosyphilis diagnosis.

171 Three of the TIL TCRs were specific for non-mutated self-antigens, two of whic

172 All sdAb were specific for NP and those tested required the C-ter

173 nique genetic architecture; some of the loci were specific for one condition, whereas others overlapp

174 all five tested SULTs, whereas Western blot was specific for only two isoforms.

175 we identified multiple genomic regions that are specific for, or absent from, type III strains compa

176 etermine whether the phosphorylation changes were specific for osmosignaling or involved cross talk w

177 ng interferon responses in monocytes and DCs is specific for p30, and represent an essential early st

178 Conversely, four of the variants appeared to be specific for PAD, including F5 p.R506Q, highlighting

179 Moreover, these effects were specific for pain, as self-report and ERP measures

180 The emitted signal was specific for PARP1 expression and, most importantly,

181 a subset of inhibitors from our panel could be specific for particular disease-associated polymorphs

182 The cytotoxicity of the VIP derivatives is specific for pathogens, because they do not affect th

183 effect is absent in LPS-activated cells and is specific for PGE2 because it cannot be reproduced by

184 s is catalyzed by PHEOPHYTINASE (PPH), which is specific for pheophytin (i.e. magnesium-free chloroph

185 ereas the transporter at blood brain barrier is specific for phospholipid form of DHA.

186 The similarity was specific for promoter regions and cerebellum and fro

187 This current decrease is specific for PSA above a limit of quantification in t

188 e report a new fluorescence-based assay that is specific for PSD and in which the presence of PS caus

189 A newly identified NB predicted to be specific for Pseudomonas aeruginosa (pyocin Sn) was p

190 Low serum erythropoietin (EPO) values were specific for PV, but normal EPO values were found a

191 The reduction in glucose production was specific for pyruvate; glucose production from glyce

192 This effect was specific for RA because control cells showed opposit

193 he structurally-related DOCK1 and DOCK2 GEFs are specific for RAC, and require ELMO (engulfment and c

194 EHop-016 is specific for Rac1 and Rac3 at concentrations of </=5

195 Akt-mediated activation in macrophages was specific for Rac1 because Akt did not increase activ

196 are guanine nucleotide exchange factors that are specific for Ras or Rap, and are important regulator

197 This observation was specific for RASFs as a reverse behavior was observe

198 ligase seven in absentia homolog (SIAH) that is specific for regulation of protesome-dependent DCC de

199 tenosynovitis at metatarsophalangeal joints was specific for rheumatoid arthritis when compared with

200 etects all tested Rickettsia spp.; the other is specific for Rickettsia rickettsii.

201 Ssu72 is unique in that it is specific for Ser(P)(5) in one orientation of the CTD

202 nt has raised hopes for therapies that would be specific for single-gene disorders and identify cellu

203 g, electrograms that exhibit MES and PMI may be specific for sites critical to reentry.

204 nts showed that the glycosyltransferase Gat1 is specific for Skp1 in Toxoplasma and also in another p

205 This effect was specific for slow wave activity, and not for sleep d

206 results show that ligand decorated liposomes are specific for Sn, since they are taken up by bone mar

207 This modulation of theta rhythmicity, which was specific for social stimuli, appeared to reflect a b

208 lation may offer therapeutic strategies that are specific for solid-phase aggregation observed in dis

209 Other product ions were found to be specific for some structures.

210 similar pattern of down-regulated genes that are specific for spermatogenesis between the two hybrids

211 zation required NMDA receptor activation and was specific for stimuli that induced LTP.

212 ies revealed that the antigenic lipopeptides are specific for strains of the M. tuberculosis complex.

213 nd Glu; and (iii) that some isoforms of Ate1 are specific for substrates bearing N-terminal Cys resid

214 e provided a hydrophobic fraction of Cu that was specific for sulfide-bound Cu in white wine but red

215 Stripping potentiometry was specific for sulfide-bound Cu in wines, and showed t

216 rning per se, we here show that D2 receptors are specific for support of a consolidated form of odor

217 re surprisingly few distinct chemotypes that are specific for SUR1-containing KATP channels.

218 but it is challenging to find peptides that are specific for targeted pests.

219 The biosensor is specific for Tdp1 even in complex biological samples,

220 The biosensor was determined to be specific for TGF-beta1 with an experimental detection

221 on and its control of the apoptotic response are specific for the amplitude of force applied.

222 tor-binding subunit and the remaining fourth are specific for the assembled glycoprotein complex, req

223 lude the genes encoding inhibitory KIRs that are specific for the C1 and C2 epitopes of HLA-C.

224 ddition, we analyzed those alterations which are specific for the combination of both stresses.

225 found 71 differentially expressed genes that are specific for the combination treatment with Doxorubi

226 Some of the package functions are specific for the domestic dog (Canis familiaris) dat

227 High-affinity interactions with MED25 are specific for the ETV1/4/5 subfamily as other ETS fac

228 Contractions are specific for the expanded allele, independently of D

229 king advantage of the types of queries which are specific for the high-throughput molecular profiling

230 s, we find that most expanded CD4(+) T cells are specific for the inducing myelin peptide MOG(35-55).

231 e phylogeny revealed a set of ~200 SNPs that are specific for the Manila strain-type, and a subset ca

232 d from humans with previous dengue infection are specific for the nonstructural and the prM structura

233 s by the major stromal molecular motor Hsp70 are specific for the physicochemical properties of the T

234 tructure and that some of these correlations are specific for the pre-diabetic state.

235 fined conditions show that TRIM32 and TRIM25 are specific for the Ubc5 family of E2-conjugating prote

236 croscopy revealed that AtTIP1;3 and AtTIP5;1 are specific for the vacuoles of the vegetative and sper

237 This assay was found to be specific for the detection of EBOV, as no nonspecific

238 Here we show that Tfr cells can be specific for the immunizing antigen, irrespective of

239 ht-related responses, 87 genes were found to be specific for the response of young developing leaves

240 These antibodies were found to be specific for the same, presumably single, non-MHC ant

241 d with a single-chain antibody, MAN-1, which is specific for the activated beta(2)-integrin Mac-1.

242 the MassMatrix algorithm) was designed that is specific for the analysis of glycopeptide anions by U

243 tudy, we describe the nanobody hC3Nb3, which is specific for the C-terminal C345c domain of human and

244 man chimeric IgE antibody (MOv18 IgE), which is specific for the cancer-associated antigen folate rec

245 tional knockout, using Hoxb7-driven Cre that is specific for the collecting ducts and a subset of dis

246 s to a similar monooxygenase, CYP92C6, which is specific for the conversion of (E,E)-geranyllinalool

247 and require the accessory factor HPF1, which is specific for the DNA damage response and switches the

248 MlghC is specific for the double C3/C5 epimer generated by Mlg

249 Here, we demonstrate that this mechanism is specific for the Env conformation and affects the eff

250 the FSC lineage, and that Wingless signaling is specific for the FSC niche whereas Hedgehog signaling

251 The recombinant mAb 131 is specific for the gamma-subunit of the fetal AChR to w

252 This effect is specific for the GluA2 subunit of the AMPAR and requi

253 d Lewis(X) antigen motifs and that SpGH95(C) is specific for the H(O)-antigen motif.

254 genetic manipulation of SRC-2 in this study is specific for the heart and thereby eliminating potent

255 The resulting hydrophobic moment vector is specific for the instantaneous conformation, and it t

256 We generated a CAR that is specific for the kappa light chain (kappa.CAR) and th

257 vered a new polysaccharide lyase family that is specific for the l-rhamnose-alpha1,4-d-glucuronic aci

258 th functional assays revealed that SpGH29(C) is specific for the Lewis(A) and Lewis(X) antigen motifs

259 positron-emitting, high-affinity ligand that is specific for the macrophage colony-stimulating factor

260 emia may consider using a cut-off point that is specific for the method of blood sampling and the met

261 ropin releasing hormone, and an agonist that is specific for the mutant.

262 O-1) and end-binding protein-1 (EB-1), which is specific for the plus end of microtubules demonstrate

263 es not contain the conserved sequence motif, is specific for the rRNA binding site of S8.

264 MspJI is specific for the sequence 5(h)mC-N-N-G or A and cleav

265 ,3)-Gal and have demonstrated that the ELISA is specific for the target and can be used to determine

266 cating that the effect of helix 12 extension is specific for the vesicle-priming step.

267 Such devices require a binding reagent that is specific for the virus of interest.

268 We demonstrate that omptin cleavage is specific for the Y. pestis and Y. pseudotuberculosis

269 The targeted neuronal ensemble was specific for the cue-induced response because stress

270 The biosensor was specific for the detection of synthetic AbetaO and g

271 for retrieval of the memory, and the memory was specific for the spatial pattern of neurons artifici

272 The assay was specific for the targeted bacteria when investigated

273 DNA methylation activity was specific for the targeted region and heritable acros

274 The sensitizing effect of Poly I:C was specific for the TLR-3 pathway because mice deficien

275 Tolerance induction was specific for the tolerogenic vaccine Ag PLP178-191 o

276 ing from the progressive engineering process was specific for the XID mutant allele versus the wild-t

277 Many were specific for the HIV-1 Env V3 loop, and this V3 spe

278 01, CD8(+) T cells that expressed CD45RA and were specific for the pp65 protein (NLVPMVATV epitope) h

279 TS analogue enzyme inhibitors are specific for their target and bind orders of magnitu

280 us cellular membrane proteins, some of which are specific for these cells.

281 independent of transcription, and appears to be specific for these membrane proteins.

282 onsiders the structural characteristics that are specific for this lipid category.

283 The regulation of beta-catenin by GSKIP is specific for this AKAP as AKAP220, which also binds P

284 n ( approximately 30% of splenic CD8 T cells were specific for this peptide at the peak of the respon

285 both HREC and abiotic surfaces, Com control was specific for those structures produced on HREC.

286 es, and IgG eluted from one of these samples was specific for THSD7A.

287 n of selected high-risk sonographic features was specific for thyroid malignancy.

288 cy of CD73-expressing immune cells seemed to be specific for TLR9 deficiency and was MyD88 independen

289 nthesis, their AspRS enzymes were thought to be specific for tRNA(Asp).

290 , in the hTSHR/NOD.H2(h4) model, enhancement is specific for TSHR Abs, with Abs to thyroglobulin and

291 s II-restricted CD4(+) T-cell responses that are specific for tumors.

292 r serendipitous discovery that this activity was specific for tyrosine in vitro, and how this in turn

293 Of these, Phep_2830 is known to be specific for unsaturated heparin disaccharides.

294 compared with a univariate approach, and to be specific for valence processing in the amygdala.

295 enes with distinct expression patterns: some are specific for vestibular hair cells, others for cochl

296 nd N-cadherin, the effect of TRPM7 silencing was specific for vimentin protein expression and STAT3 p

297 -violent offenders, indicating that findings were specific for violent offending, and not largely att

298 ary with population characteristics, and may be specific for virulence factor VacA.

299 n-fusion events, suggesting that this effect is specific for Wnt-5a alone.

300 Moreover, the ULISA is specific for ZEA and its metabolites (alpha- and beta