ライフサイエンスコーパス: be specific to

1 s but less is known about risk variants that are specific to a given disorder.

2 ion compared to cis-acting eQTLs and tend to be specific to a single region (SR-eQTL) of the brain; (

3 sting that its effect on the paternal genome is specific to a subset of histone marks.

4 The Aspergillus branching response is specific to a subset of oxylipins and is signaled thr

5 Second, the deficits caused by SC inhibition were specific to a temporal epoch coincident with early

6 dentified two novel risk loci that appear to be specific to AAs: GPC5 and RBFOX1 (PAA < 5 x 10-9).

7 no model exists of effective mentorship that is specific to academic surgery.

8 This regulation of mTORC1 is specific to activation of mTORC1 by amino acid stimul

9 rovement in independent patient cohorts, and were specific to active compared with sham stimulation.

10 nclude the earliest known cytopathology that is specific to AD and that affects endosomes and induces

11 Moreover, this effect is specific to AKAP150, as viral overexpression of a PKA

12 ting that mTORC1's role in habitual behavior is specific to alcohol.

13 Importantly, our results are specific to alphaSacetyl because alphaSun does not d

14 This regulation is shown to be specific to ALV, as disruption of the FACT complex di

15 ffected by Alzheimer's disease; associations were specific to amyloid PET in cognitively unimpaired a

16 when the individual's pre-existing immunity was specific to an HA protein antigenically distinct fro

17 ts demonstrated a wide array of changes that were specific to anesthesia-exposed subjects, which supp

18 ubfield analysis revealed that this relation was specific to anterior CA2/3 but not CA1.

19 Viral loss was specific to antiviral nucleoside treatment and not i

20 e degree to which these process dysfunctions are specific to anxiety.

21 tability, ADHD, and anxiety, while the third was specific to anxiety.

22 ved reductions of cerebral Abeta amyloidosis are specific to any individual antibiotic or require the

23 rey matter atrophy in cognitively unimpaired was specific to APOE epsilon4 carriers (P < 0.05).

24 tify two novel loci (8p23 and 8q24) that may be specific to asthma risk in African ancestry populatio

25 ry astrocyte disease because GFAP expression is specific to astrocytes in the central nervous system

26 r, whether the role of LET-99 in cytokinesis is specific to asymmetric division and whether it acts t

27 This stabilization effect was specific to ATP6V0C, as overexpression of another su

28 esponse to A3A activity, synthetic lethality was specific to ATR signaling via Chk1 and did not occur

29 age does not depend on neural processes that are specific to auditory speech perception.

30 The associations were specific to AVP, as ASD cases and controls did not

31 genetic alterations in DLBCL, some of which are specific to B cell lymphomas, whereas others can als

32 erent sets of genes, indicating that the FGS is specific to B73.

33 en up by inflammatory lesions and appears to be specific to bacterial infections by targeting the mal

34 identified a DNA methylation signature that is specific to BCVY and have shown that epigenetic age-a

35 This dopamine profile is specific to behavioral choice, scalable with interval

36 such as identifying retinal biomarkers that are specific to biomarker-positive AD, clinical syndrome

37 This functional conservation is specific to BLM, as human GAL4 > UASp::RECQL was not

38 Antibodies that are specific to both CD1d and the presented antigen can

39 sults reveal that the local changes in K-Ras are specific to bound nucleotide (GTP or GDP), and we pr

40 Post hoc analyses suggested that this effect was specific to boys (interaction p = 0.02).

41 it remains unclear whether that association is specific to Campylobacter jejuni/coli.

42 ma risk, and rs3817963 (6p21.3, BTNL2) which is specific to cases with EGFR mutations.

43 The assay was specific to cattle, pigs and fish, having been teste

44 drive species' responses, and responses may be specific to certain life stages or times of year.

45 that this inflammatory neuroimmune pathology is specific to certain disease etiologies.

46 al neurotoxicity and few assessment measures are specific to children.

47 ating that the synaptogenic actions of menin are specific to cholinergic regulation.

48 ion, leading to CHIP through mechanisms that are specific to clonal haematopoiesis as well as shared

49 s can increase competitive interactions that are specific to (co)evolved community members.

50 These effects were specific to cognitive rather than affective ToM.

51 This deficit was specific to conditioned inhibition; an excitatory pr

52 ms from the onset of the event boundary) and was specific to context shifts that were preceded by an

53 These effects were specific to CRCs overexpressing IGF-2, as MEDI-573

54 research for safe medication practices that is specific to critically ill patients.

55 reover, the beneficial effects of experience were specific to cruising and not crawling, although bot

56 This tuning of behavioral responses was specific to cues associated with smaller-than-expect

57 gregated into two major clusters: those that are specific to cycling cells and retained throughout th

58 This mechanism is specific to D1 receptor-expressing MSNs.

59 wn, we determined these synaptic adaptations were specific to D1R-MSNs relative to non-D1R-MSNs.

60 Suppression by the mps mutation is specific to Deltalsr2; it does not rescue the maturat

61 Reducing a slow nonlinear component that is specific to dendritic inhibitory inputs and mediated

62 This ASD-associated gene cluster was specific to developing Purkinje cells and not detect

63 hly differential, producing transcripts that are specific to developmental periods or cell lineages.

64 These alterations are specific to dietary fat but not carbohydrate or prot

65 ood cell, lipid and inflammatory traits that are specific to different CHIP driver genes.

66 pass a variety of regenerative pathways that are specific to different types of injury.

67 Furthermore, the contrast effects were specific to different types of adversity.

68 Our method is specific to direct CPC reprogramming, whereas CASD re

69 ettlement reflect microbial communities that are specific to discrete habitats.

70 nt expression in MFS patients, many of which were specific to diseased samples.

71 Moreover, the proposed method was specific to distinguish SARS-CoV and SARS-CoV-2 sequ

72 In addition, this effect is specific to DLL1, as other Notch ligands (DLL3, JAGGE

73 of the nanoparticle-released GSK3 inhibitor are specific to donor progenitor/stem cells and achieved

74 These effects were specific to drug class.

75 thus observed with graphene based capacitors were specific to E. coli O157:H7 strain with a sensitivi

76 o find hundreds of piRNA-producing loci that are specific to each strain.

77 deregulation, different biological processes are specific to each striatum region according to the tr

78 Capsid proteins are specific to each virus and can be used as a biomarke

79 Cell size is specific to each species and impacts cell function.

80 e that it calls upon a response pattern that is specific to each underlying associative structure.

81 etic and non-shared environmental influences were specific to each anxiety construct.

82 contain contrasting levels of phenolics that were specific to each fruit part.

83 ristics in multiple cell types tested, which were specific to each isolate and did not group accordin

84 ed dynamic changes in nodule methylomes that were specific to each nodule stage, occurred in a sequen

85 gnitude and activation energy of attack rate were specific to each predator, which varied in mobility

86 e those in the adjacent nsP1 encoding region are specific to either vertebrate or invertebrate host c

87 RBC uptake by PMos was specific to endothelial-attached sickle, but not con

88 d that stimulation of Pso2 nuclease activity is specific to eukaryotic RecQ4 subfamily helicases, and

89 A3s are specific to eutherian mammals because no direct homo

90 ications and underlying pathophysiology that are specific to extracorporeal membrane oxygenation.

91 nhanced processivity on trailing barbed ends is specific to fascin bundles, with no enhancement on fi

92 iatal networks encode prediction errors that are specific to feature values of different dimensions o

93 gence between metabolic and neural processes was specific to feedforward connections linking the visu

94 env copy number, suggesting that this effect is specific to FeLV-LTR elements.

95 phosphorylation sites, the majority of which were specific to filamentous fungi and distributed throu

96 This protracted development was specific to first-person perspective motion through

97 types, we show that the DNAJB1-PRKACA fusion is specific to FLCs.

98 This function is specific to for pr1 neurons in the VNC, guiding a dev

99 that the confirmation bias in learning rates was specific to free choices, but was independent of out

100 emission factors (EFs) for cookstoves, which are specific to fuel type and cookstove design.

101 All interactions were specific to germination and only weakly affected gr

102 related genes in R. irregularis and G. rosea are specific to Glomeromycotina.

103 The phenomenon was specific to GLUT4 because other recycling proteins w

104 ces include the development of guidance that is specific to goals of morbidity control and eliminatio

105 er the last 80,000 years to discover that it was specific to H. sapiens and present in non-Africans 4

106 s applies to social contexts, and whether it is specific to harmful intent attributions, the live exp

107 sociation of lipid rafts with autophagosomes was specific to HCV, as it was not detected in autophago

108 or target sites of RNA-binding proteins that are specific to hematopoietic cells, thus unraveling pot

109 neurobehavioral adaptations observed herein are specific to high-sugar and/or nonnutritive-sweetened

110 Previously thought to be specific to higher primates, we identified transient

111 Moreover, this relationship appears to be specific to how people experience prediction and is n

112 ures on clones are modulated by factors that are specific to human populations.

113 udgments; is stronger for male participants; is specific to human faces when compared to pets, flower

114 These responses were specific to IAPV infection, suggestive of pathogen

115 ajority of the incPRINT-defined interactions are specific to individual functional regions of the lar

116 nd single-nucleotide variants, many of which are specific to individual human populations.

117 rns indicate that FMRP expression appears to be specific to individual neuronal cell groups instead o

118 The extent to which variability in ICU use is specific to individual diagnoses or is a function of

119 HIP status, including one locus at TET2 that was specific to individuals of African ancestry.

120 tes may be modified by hours of sleep, as it was specific to individuals reporting >=7 hours of sleep

121 may respond to Cd exposure in a manner that is specific to infant gender.

122 These findings appeared to be specific to inhibition during the post-lever press pe

123 Here, we report that this form of plasticity is specific to intracortical inputs to V1 L2/3 neurons a

124 g multidimensional matrix of isotopic shifts is specific to isomers, providing a fundamentally new ap

125 uingly, the Ca(2+) regulation of Kv4 current was specific to KChIP2b and KChIP2c splice isoforms that

126 These processes were specific to kidney glomeruli where metabolic signal

127 The increase is specific to L2/3 neurons and absent on apical dendrit

128 ting approach to identify cell subtypes that are specific to LAM.

129 This typology is usually thought to be specific to language and in part lexically encoded in

130 We detected significant GxE that was specific to larvae and adults for cold and heat hard

131 t what changes to population activity in PFC are specific to learning these relationships.

132 Connectivity to this region was specific to lesions causing freezing of gait compare

133 matched the onset of anhedonic behavior and were specific to LHb neurons that distinguished reward a

134 ng the conformational changes in this region are specific to ligand function.

135 as allowed for the development of drugs that are specific to LMS and has begun to shed light on the s

136 Results are specific to Long Island Sound, but the approach is t

137 the role of Tof1 in preventing fork breakage is specific to long CAG tracts of 85 or more repeats.

138 ated aversion and the decrease in excitation were specific to MD inputs; activating basolateral amygd

139 nding and the hippocampal inhibition network was specific to MDD but not HV.

140 Declines were steeper in girls than boys and were specific to measles deaths.

141 The fluorescence-based neutralization assay is specific to measure COVID-19 neutralizing antibodies

142 ium-sized vesicles, suggesting that they may be specific to microvesicles as opposed to exosomes.

143 The resistance of I/LnJ BMDMs was specific to MNV, since the cells supported infection

144 ntify putative protein-coding sequences that are specific to mosquito genomes.

145 ns, high-risk presentation and poor outcomes were specific to multi-hit patients only.

146 hich prospectively collect patient data that are specific to multiple sclerosis as part of routine cl

147 he effects of psychological adaptations that are specific to music (e.g., rhythmic entrainment) and t

148 s presence in a clade of the MLO family that is specific to mycorrhizal-host species, we investigated

149 avonoid and terpenoid biosynthesis in leaves are specific to mycorrhization.

150 state, whereas the empathic distress marker was specific to negative emotion.

151 t postero-medial DMN down-regulation may not be specific to neurodegenerative processes but may be mo

152 TAD borders that are specific to neuronal cells are enriched in enhancers

153 These effects are specific to neuronally-derived proteins, which sugge

154 mon to many cell types as well as those that are specific to neurons.

155 e UK Biobank suggested that this association was specific to nondihydropyridine CCBs (hazard ratio 1.

156 Interestingly, the effect of PD184161 was specific to nonhypoxic activators, since HIF-1alpha

157 ression results from glycinergic inputs that are specific to ON-DSGCs and are absent in ONOFF-DSGCs.

158 Regions identified were specific to one or both genders.

159 Antibodies that are specific to organ donor HLA have been involved in th

160 However, an unknown fraction of GIs may be specific to other conditions.

161 mutant mouse line, we show that innervation is specific to ovary development, is not dependent on th

162 we ask whether sensory system abnormalities are specific to particular types of dystonia, whether a

163 versus bent disulfide bond-containing CDRH3 is specific to particular HCV-infected individuals, we s

164 trength, indicating that ensemble plasticity is specific to partner approach.

165 Findings are specific to patients with AHF who present to the ED

166 ially overlook crucial unmeasured areas that are specific to patients with Barrett's oesophagus.

167 the identification of a glycan epitope that is specific to phloem sieve element cell walls in severa

168 a 'core' plastisphere community exists that is specific to plastic is currently a topic of intense i

169 T1, demonstrating that NM hTau pathogenicity is specific to postnatal development.

170 llmarks of naive pluripotency, five of which are specific to primates.

171 olism and tricarboxylic acid cycle node that was specific to prostate-derived cancer cells and cancer

172 ition, the extent to which these alterations are specific to psychosis or represent a transdiagnostic

173 idence of decline, suggesting that a decline is specific to psychosis.

174 eriments showed that the effects of garcinol are specific to reactivated memories only, temporally co

175 hange across conditions, hippocampal effects were specific to recall.

176 y is linked to working memory impairment and is specific to repeated exposure to multiple stressors.

177 cts independently of dNTP concentrations and is specific to resting CD4 T cells.

178 Crucially, this reactivity was specific to RF as it was absent in RF- patient and h

179 This effect was specific to RI of cocaine seeking as ZIP did not dis

180 test whether miR-21 and miR-221 upregulation is specific to RV cellular response to mechanical and ho

181 concomitant appraisals of self-focus, which are specific to sadness, than by concomitant appraisals

182 Notably, one is specific to SARS-CoV-2, which is located in close pro

183 It is unclear, however, which iFC changes are specific to schizophrenia compared with those of oth

184 psychological functions, and whether decline is specific to schizophrenia.

185 ons and seedling age while qAG1-2 and qAG7-4 were specific to screening methods.

186 als with coronavirus disease 2019 (COVID-19) are specific to severe acute respiratory syndrome corona

187 marker, and the behavioral cost it entails, are specific to situations that involve a destruction of

188 This uptake pathway is specific to SLAMF1-positive cells and occurs within 6

189 These effects are specific to SNX-1 and RME-8, as loss of other retrom

190 OXT was well tolerated, and its effects were specific to social functioning, with no observed de

191 We found view symmetric representations were specific to some face-selective regions, but not ot

192 Some metabolic pathways were specific to some MAGs, including sulfur oxidation,

193 gene-hunting research; (ii) some genes will be specific to spatial ability, independent of g; and (i

194 Cap-independent upregulation was specific to spines with small, astrocyte-associated

195 not known whether neighborhood inequalities are specific to stroke survival or similar to mortality

196 , emphasizing the analytical approaches that are specific to studying gene expression in single cells

197 These impacts were specific to substitutions with isoleucine residues

198 However, the effect was specific to thapsigargin, as tunicamycin and the sub

199 These results are specific to the alpha band and build upon emerging e

200 s also hold after temporal recalibration and are specific to the alpha band, suggesting that alpha ba

201 While these findings are specific to the case study building, location, and t

202 ow that male steroid production and transfer are specific to the Cellia and therefore represent a syn

203 To assess if those observations are specific to the cotton rat and to elucidate the mech

204 SHAP values, highlighting the features that are specific to the defined GOI.

205 f blood-stage parasites, including some that are specific to the elusive P. vivax male gametocytes, a

206 To clarify whether these abnormalities are specific to the epileptogenic zone (EZ), we characte

207 nt of trafficking and cAMP binding, and they are specific to the HCN4 isoform.

208 ated immune evasion, thus to mechanisms that are specific to the in vivo setting.

209 gested to underlie cancer cell dissemination are specific to the metastatic process, as opposed to re

210 d cross-links in vivo, suggesting that MrfAB are specific to the monoadduct or the intrastrand cross-

211 p90-interacting proteins, including 111 that are specific to the pathogen.

212 d for constructing multi-omics networks that are specific to the phenotype.

213 ups of interest, the degree to which results are specific to the question at hand is not generally as

214 learning tools have limitations, since they are specific to the RiPPclass they are trained for and a

215 flow assay detects IgG and IgM isotypes that are specific to the SARS-CoV-2 receptor binding domain o

216 ion and that such effects on imprinted genes are specific to the species combination.

217 By using antibody fragments that are specific to the target biomolecule, the new methodol

218 nctionalized by immobilizing antibodies that are specific to the target cells.

219 azithromycin on the bacterial microbiota may be specific to the age and geographic setting of its rec

220 This novel mechanism might be specific to the maintenance of gaze direction across

221 duction-related genes on sex chromosomes may be specific to the male germ line.

222 vely few splicing factors have been shown to be specific to the minor spliceosome.

223 g that Spc has a chaperone function that may be specific to the relatively short PilA monomers that a

224 We also demonstrated that this effect may be specific to the renin-angiotensin system as it did no

225 Importantly, several pathways were found to be specific to the severe isolate, including triggering

226 g induction of an immune response appears to be specific to the tbxt/tbxt2 morpholinos.

227 We additionally identified thymol as being specific to the accession.

228 in function, but it is unknown whether this is specific to the abdominal wall or due to an improveme

229 antibodies, indicating this unique response is specific to the Ad4 serotype rather than the transgen

230 y for pERK, whereas PKCdelta phosphorylation is specific to the alternate pathway.

231 The axoneme exit defect is specific to the caudal axonemes, which exit from the

232 trated that the transcriptional circuit that is specific to the cranial neural crest emerged via the

233 components of a transcriptional circuit that is specific to the cranial neural crest in amniotes and

234 tissue type on feature quantification, which is specific to the data structure of the sequencing type

235 r regulatory mechanism for RA signaling that is specific to the developing forebrain.

236 study a trait consisting of coloration that is specific to the embryo and absent from postembryonic

237 to the dynamic local lipid environment that is specific to the extracellular lipid leaflet.

238 recent work has suggested that Fog signaling is specific to the fast mode of gastrulation found in so

239 ed to stimulus uncertainty, that this tuning is specific to the features encoded by these neurons and

240 The effect on tendon cell expansion is specific to the geranylgeranylation branch of the mev

241 Here, we tested if the MFS is specific to the human FG or if the MFS is also identi

242 gesting that CpsY function in immune evasion is specific to the human host.

243 Notably, this correlation effect is specific to the ictal wavefront and is absent interic

244 We show that the fine structure of SCCs is specific to the identity of natural stimuli and chang

245 iation in the urinary metabolome of children is specific to the individual, underlining the potential

246 ory effect on EphA2 activation in cells that is specific to the ligand-independent conformation of th

247 This reorganization is specific to the neuronal subpopulation most relevant

248 ntly, this MDA5-dependent antiviral response is specific to the pancreas of rotavirus-infected mice,

249 we learn that the inhibition effect of EGCG is specific to the peptide sequence, while those of resv

250 nation, followed by proteasomal degradation, is specific to the presence of glucose.

251 sulfated hyaluronan, indicating that binding is specific to the presence of sulfate groups.

252 al homologs of the neutralizing Ab MR78 that is specific to the receptor binding site (RBS) of MARV g

253 This effect is specific to the spleen, revealing a unique molecular

254 Moreover, we found that motion VPL is specific to the trained stimulus direction, speed, si

255 ble, our data suggest that this contribution is specific to the type of Prph2 mutation.

256 Control experiments showed the effect was specific to the agent-to-object motion direction and

257 This inhibition (exclusion) was specific to the cognate conjugation machinery and th

258 The inhibition of immune responses was specific to the conjugated antigen, avoiding systemi

259 uring training, and the conditioned response was specific to the CS and reflected the US valence.

260 This pattern of plasticity was specific to the gamma band as lower frequency oscill

261 This differential developmental expression was specific to the hippocampus, as both mice and rats e

262 This pattern was specific to the hippocampus, most pronounced in the

263 is effect of compromised astroglial function was specific to the NTS as expression of dnSNARE in astr

264 This finding was specific to the nucleus-enriched fraction and was no

265 The pabA growth defect was specific to the red blood cell component of human bl

266 ion of activated regulatory T cells at birth was specific to the sensitized-tolerant infants, which m

267 and many of the binding sites in these genes were specific to the A. alpina lineage.

268 r response outset, fear-related signals that were specific to the fear-associated grating orientation

269 rected); therefore, internetwork alterations were specific to the FEP.

270 Brain-sleep relationships were specific to the hippocampus; no significant relatio

271 , most of the differentially regulated genes were specific to the interactions with either P. pannosa

272 These effects were specific to the overexpression of FAAH because they

273 To test whether effects were specific to the social component of the isolation e

274 Results were specific to the subject's unique breast cancer mole

275 Chemogenetic effects were specific to the targeted dorsal hippocampus, as hip

276 Reductions in neural variability were specific to the visual system and larger in the con

277 We identified genes whose expression is specific to these cell types, and from these genes, w

278 This effect was specific to theta (4 Hz) and did not occur in slower

279 8 activator triggers allosteric changes that are specific to this 20S/PA28 pair.

280 the MASP multigene family of proteins MASPs are specific to this parasite and characterized by a con

281 her the unanticipated finding of ulcerations is specific to this tenofovir disoproxil fumarate ring o

282 association with lower leptin concentrations was specific to this ancestry (P = 2 x 10(-16), n = 3,90

283 e binding protein, finding that the sequence is specific to those rotavirus strains that cause obstru

284 This "activation selectivity" was specific to those brain systems that were central to

285 potential epilepsy-risk eQTLs, some of which are specific to tissue from patients with mesial tempora

286 association of family size with conservatism is specific to traditional-family issues and can be attr

287 ), which was mediated by the Fc receptor and was specific to trastuzumab.

288 n children as well as design challenges that are specific to trials that involve young cancer patient

289 of SMAD5, and this LEFTY1-BMPR2 interaction is specific to tumor-initiating cells in triple-negative

290 These results are specific to UbE2E1 as knockdown of UbE2D E2s does no

291 We show that the reagents reported here are specific to UCHL1 over all other DUBs detectable by

292 Crucially, this effect is specific to upright faces, whereas inverted faces pre

293 o induce ITGB3 in endothelial cells seems to be specific to vIL-6, as overexpression of hIL-6 alone d

294 ngs suggest that FEF visual target selection is specific to visual judgments made on the basis of sal

295 These effects were specific to vmPFC and not to striatum.

296 The association with myelination was specific to waiting impulsivity: R1 was not associat

297 corroborated that two of the isolated clones were specific to wheat, barley and rye proteins.

298 d the concept of risk-enhancing factors that are specific to women and are associated with an increas

299 k, we isolated more than 100 human mAbs that are specific to Zika virus, assessed their function, ide

300 t ZIKV nonstructural protein 1 (NS1) antigen were specific to ZIKV infection, and IgG avidity reveale