ライフサイエンスコーパス: bead

1 8 um(2) s(-1) K(-1) for a 10 um polystyrene bead.

2 with Cappuccino in bulk pyrene assays and on beads.

3 dead Cryptococcus neoformans cells, or inert beads.

4 nucleotides coupled to streptavidin magnetic beads.

5 th avidin protein immobilized on polystyrene beads.

6 s from the 10x platform may contain multiple beads.

7 dehydrogenation on platinized gamma-alumina beads.

8 Schistosomamansoni eggs and inert egg-sized beads.

9 CM) but not from those isolated without CD3 beads.

10 ugated with HRP onto the surface of magnetic beads.

11 r (VI) to Cr (III) in graphene-based polymer beads.

12 then visualized by decoration with magnetic beads.

13 ngulfing rod-shaped bacteria and ellipsoidal beads.

14 theter to administer 300- to 500-mum embolic beads.

15 m stool and emesis samples using HBGA-coated beads.

16 brary on the surface of 8 million monoclonal beads.

17 f C. elegans, with greater effects by the PS beads.

18 ncapsulated successfully in calcium alginate beads.

19 ysuccinimide (NHS) ester attached on agarose beads.

20 g of biotinylated peptides from streptavidin beads.

21 igated the toxic effects of polystyrene (PS) beads (0.1-10.0 mum) and the underlying mechanisms there

22 trating network or core-shell-structured gel beads-a rare example of a supramolecular gel formulated

23 This microbe bead adsorbent contained a homogenous distribution of ce

24 PS and SiO(2) beads affected the food availability of C. elegans, with

25 nia were captured with oligo (dT)-conjugated beads after UV-crosslinking and profiled by proteomics (

26 of long DNA fragments (15-20 kb) by magnetic beads, after enzymatic extension of oligonucleotides hyb

27 inal microvascular abnormalities, and venous beading, agreement was moderate (weighted kappa, 0.41 to

28 A FACS-based sorting of the library beads allowed recovery of hits improved in Kd over wild-

29 d its compatibility with protein AG-magnetic beads allowed the integration of SP-PCR.

30 spheroids by culturing them around Matrigel beads allowing superficial access to the apical membrane

31 reformed DSA were detected by single antigen beads alone.

32 Beads also induce granulomas rapidly, through a foreign

33 in the force constant of the bond between a bead and a cell of typically 20 pN/mum are clearly detec

34 s of cultured endothelial cells with a glass bead and evaluated two different approaches for interpre

35 nes within a group of cells in the notochord bead and for promoting wound-induced proliferation requi

36 ied to immobilize the pectinase on the glass bead and the finding was compared with free enzyme.

37 ulent, intermediate to slow flow, and venous beading and looping presented with relatively high flow

38 Cappuccino in vivo, we immobilized Spire on beads and added Cappuccino and actin.

39 performance using sub-resolution fluorescent beads and applied to a test sample consisting of human b

40 A mixture of Dsg beads and Dsc beads formed large aggregates, confirming

41 eated clinically with localized drug-eluting beads and for which DNA-PKcs activity is reported to con

42 -TurboID are then enriched with streptavidin beads and identified by mass spectrometry.

43 ce improved optically decodable mRNA capture beads and implement a more scalable and simplified optic

44 ies on the encapsulation of cells in agarose beads and labeling breaks directly and specifically with

45 used two types of targets (solid polystyrene beads and liquid lipid droplets) to investigate the infl

46 Using multiplexed inhibitor beads and mass spectrometry, we mapped the kinome landsc

47 ed by conjugating substrates to paramagnetic beads and measuring the conversion of substrates to prod

48 are probed by using zwitterionic polystyrene beads and performing STD-NMR experiments at high, low, a

49 f the LT-encoded capture and carrier CaCO(3) beads and the short-lived emission of the dye-stained ba

50 in simulation experiments using fluorescent beads and then apply them to correcting measurements of

51 retain pointed ends of actin filaments near beads and we identified Spire's barbed-end binding domai

52 uorescent indicators of the TF-DNA bound (on bead) and unbound states.

53 ed processability with low yield (2D film or beads) and high fabrication cost (high temperature, air/

54 nanobioprobe, MB-p53Ag/BSA as a nanomagnetic bead, and microwell ELISA plate, MTP-p53Ag/BSA were comp

55 on closely govern the tube radius, number of beads, and the bead morphology.

56 To this end, we developed a coarse-grained bead-and-spring model and investigated its properties th

57 Using the conventional 'on-bead' approach, we reconstituted Escherichia coli protei

58 ical tubes, but they may occasionally have a beaded architecture along the tube.

59 iquely shaped and structured LMWG-filled gel beads are a versatile platform technology with great pot

60 As SpliMLiB beads are monoclonal, they were amenable to direct funct

61 In this approach, beads are simply dropcast onto a microscope slide and dr

62 Nonetheless, when the beads are subjected to medium or low magnetic forces, co

63 In a PCR tube, millions of clonally barcoded beads are used to uniquely barcode long DNA molecules in

64 We conclude that multiplex bead array assessment of non-HLA antibodies identifies c

65 gh literature search to generate a multiplex bead array.

66 s, this work used BSA immobilized in agarose beads as a novel solid-phase extraction method for quant

67 terogeneous assays commonly utilize magnetic beads as a solid phase.

68 ocapsid (N) protein detection using magnetic beads as support of immunological chain and secondary an

69 ment and quality control (QC) of a multiplex bead assay (MBA) for three sero-surveys in Haiti.

70 theria, and tetanus, using Luminex multiplex bead assay (MBA).

71 Using a magnetic bead assay and a recombinant SARS-CoV-2 spike protein fr

72 LA antibodies measured by the single-antigen bead assay from 627 waitlisted patients who subsequently

73 We used the three-bead assay to minimize the vertical force component and

74 alternative approach to ETFA is the "Fibrin Bead Assay" (FBA), based on the use of Cytodex 3 microsp

75 Using the three-bead assay, we also found that not all microtubule proto

76 optical tweezers and the conventional single-bead assay, we show that detachment of kinesin from the

77 0-fold longer than observed using the single-bead assay.

78 ns were determined using a multiplex protein bead assay.

79 ntial pathogenicity of pemphigus antibodies, bead assays coated with recombinant Dsg1, Dsc1, Dsg3, or

80 R biopsies (n = 71) were tested for DSA with bead assays.

81 to-date the most sensitive NAzyme-mediated, bead-based approach, that does not rely on target amplif

82 es has developed a fully automated multiplex bead-based assay for the detection of IgM and IgG antibo

83 Ubr1-mediated ubiquitination, we developed a bead-based assay with covalently immobilized but releasa

84 Using a bead-based assay, we confirmed that binding of (131)I-CR

85 ed them for 33 cytokines using a multiplexed bead-based assay.

86 sequencing, liposomal nanoallergen display, bead-based assays, and protein chimeras have been used i

87 ated mathematical model for surface coverage bead-based assays.

88 53 immune mediators using multiplex magnetic bead-based assays.

89 d enzymes and its ability to perform complex bead-based assays.

90 ed using avidin-biotin particles as a simple bead-based bioassay model.

91 Described is a modular bead-based biosensor design that can be applied to such

92 dual droplet of embryo culture medium with a bead-based digital microfluidic chip.

93 te this model, we analyze a semi-homogeneous bead-based electronic enzyme-linked immunosorbent assay

94 lyzed specimens with a 62-cytokine multiplex bead-based enzyme-linked immunosorbent assay.

95 Bead-based epitope assay (BBEA) was used to quantitate t

96 e a simple workflow which automates magnetic bead-based extraction of NAs with a one-step transfer to

97 ils without inflammation) was measured via a bead-based flow cytometric analysis.

98 ntegration of aptamers and antibodies into a bead-based fluorescence sandwich immunoassay implemented

99 (n = 1154) was laboratory tested for HRP2 by bead-based immunoassay and for P. falciparum 18S rDNA by

100 ralis was measured in 0-12-year-olds using a bead-based immunoassay before and after ivermectin mass

101 Bead-based immunoassays have shown great promise for rap

102 Magnetic bead-based immunoassays were utilized to measure the con

103 ,750-fold and is compatible with multiplexed bead-based immunoassays, immunomicroarrays, flow cytomet

104 imal recovery of these DNAs using a magnetic bead-based isolation method.

105 A and ccf-nDNA recovery that uses a magnetic bead-based isolation process on an automated 96-well pla

106 Using the bead-based laboratory assay as the gold standard, the se

107 Here, we adapted an immunomagnetic bead-based method to isolate plasma CD31(+) EVs to harve

108 lification (RCA) bioassay and an (2) agarose bead-based microfluidic device for the affinity chromato

109 s from cases, controls, and siblings using a bead-based multiplex assay.

110 dressed this challenge by combining magnetic-bead-based pathogen concentration and solid-phase PCR (S

111 The bead-based serological assay for quantitation of SARS-Co

112 Herein, we report a bead-based strategy to measure the group-transfer activi

113 Here, we present a customizable bead-based system capable of simultaneously binding to l

114 Existing scRNA-seq platforms utilize bead-based technologies uniquely barcoding individual ce

115 lained by styrene monomers leaching from the beads because chemical activities of styrene in PS suspe

116 otin linkers and captured using streptavidin beads before library production and high-throughput sequ

117 cs (DM) to automate the movement of magnetic beads between small volumes of reagents commonly employe

118 actor is demonstrated by moving paramagnetic beads between two spatially separate solutions with diff

119 rotein (p53Ag) immobilized onto nanomagnetic beads, blocked with BSA (MB-p53Ag/BSA) for capture and s

120 cal forces of different modes via a magnetic bead bound to the integrins on a cell and quantified cel

121 ated the TPW for silica columns and magnetic beads by demonstrating significant improvements in perfo

122 r mediator of phagocytosis of CD20-opsonized beads by FcgammaRIIIB WT and null PMNs.

123 ted in the serum (sDSA) using single antigen bead, C1q, and C3d assays combined with the study of int

124 A single PdNP-loaded gel bead can catalyse the Suzuki-Miyaura reaction, constitut

125 The beads can be detected with steady-state and time-resolve

126 henomenon that some liquid droplets or solid beads can spontaneously move on homogeneous surfaces by

127 ble of differentiating between bare magnetic beads, cancer cells and bead-cell aggregates based on th

128 rated that graphene oxide (GO) based polymer beads cannot only adsorb Cr (VI) via electrostatic attra

129 antibodies (anti-p53aAbs) using nanomagnetic beads capture probe and anti-IgG functionalized-fluoresc

130 Our functionalized beads capture secreted molecules (e.g., hepatocyte growt

131 current generation of commercially available beads carries four lanthanide elements (cerium, europium

132 etween bare magnetic beads, cancer cells and bead-cell aggregates based on their various impedance an

133 f ADCs from serum with streptavidin magnetic beads coated with a generic biotinylated antihuman captu

134 r point-of-care (POC) applications; magnetic beads coated with AB-specific aptamers were used to capt

135 combination with in vitro motility assays of beads coated with formins, our model allowed us to chara

136 Magnetic beads coated with metabolic enzymes were used to make po

137 Here, we use pairs of optically trapped beads coated with SNARE-free synthetic membranes to inve

138 lective affinity purification using magnetic beads coated with Strep-Tactin.

139 microfluidic systems is limited by the high bead concentrations required for efficient extraction ac

140 on therapy with CytoSorb (CS) porous polymer beads could improve survival after a lethal aflatoxin do

141 ted CTX-OCT was then loaded onto Ca-alginate-beads (CTX-OCT-Alg), which were characterized for drug i

142 arterial chemoembolization with drug-eluting beads (DEB-TACE).

143 n the second part of the model, drug eluding beads (DEBs) carrying the chemotherapeutic drug doxorubi

144 combination of this technique with magnetic beads detection results in a simple and ultrasensitive c

145 tinylated antihuman capture reagent, (2) "on-bead" digestion with IdeS and/or PNGase F, and (3) reduc

146 Assessment included bead distribution at x-ray imaging and histologic examin

147 The inclusion of GO in the polymer beads dramatically increased the potential of Cr (VI) up

148 ge of diamagnetic objects (e.g., polystyrene beads, drug delivery microcapsules, and living cells) ar

149 h-throughput chemical conversion on barcoded beads, efficiently marking newly transcribed mRNAs with

150 in bone marrow mononuclear cells by BEAMing (beads, emulsion, amplification, magnetics) digital polym

151 DNA-functionalized beads enable efficient mixing and spatial separation, wh

152 ocal soma stimulations with micrometer-sized beads evoke transient responses at low forces of ~220 nN

153 te how microplastics of a variety of shapes (bead, fiber, and fragment), in combination with the alga

154 n-MTEX and HDs exosomes were evaluated by on-bead flow cytometry.

155 After an incubation time of 30 s, bead fluorescence is measured using a high-speed camera

156 nomolar sensitivity with visual detection of bead fluorescence.

157 citrullinated histones within the notochord bead following tissue injury.

158 an average fluorescence density of a single bead for an accurate fluorescence-based exosome quantifi

159 SMV was recovered from H type III-coated beads for 13 stool specimens out of 27 SMV-positive spec

160 By using standard density glass beads for calibration, MagLev showed that the levitated

161 A mixture of Dsg beads and Dsc beads formed large aggregates, confirming that the heter

162 mprove the extraction efficiency of magnetic beads from aqueous nanoliter-sized droplets by 2 orders

163 discontinuity in the energy that impedes two beads from fusing.

164 rontium isotope analyses of ostrich eggshell beads from highland Lesotho, and associated strontium is

165 apid and efficient filtration of polystyrene beads from small molecules and surface bound red blood c

166 earch is focused on the application of glass beads (GBs) in fixed biofilm reactor (FBR) for the treat

167 tiple controlled-release pellets, particles, beads, granules, etc.

168 erial because the same-sized silica (SiO(2)) beads had considerably less impact, probably due to thei

169 The use of specific captured beads had the additional benefit of stabilizing miR-122

170 Protein AG-magnetic beads immobilized with antisalmonella antibody could eff

171 measured using the fluorescence-based micro-bead immunosorbent assay.

172 The volume of bead in tumor was a significant predictive factor for lo

173 two ways: first, charges are assigned to CG beads in an effort to reproduce molecular multipole mome

174 n, their performance was further verified on beads in bulk and in femtoliter-sized microwells.

175 zers and tracked the 3D position of over 100 beads in real time on a generic CPU.

176 By incorporating silica beads in the microreactors, the surface area of the soli

177 mployed for reproducible sample handling and bead injection into the acoustic trap.

178 We used a bead injection technique to increase IOP in mice of both

179 th field control over levitating polystyrene beads into various configurations.

180 cally used to elute the NAs off the magnetic beads is replaced by a carefully selected PCR solution,

181 ence of conditioned medium obtained from CD3 bead-isolated T cells (Tc CM) but not from those isolate

182 template chemistry called compartmentalized bead labelling and demonstrate it by the directed evolut

183 es on bead or sensor surfaces, attachment of bead labels to sensor surfaces, and generation of electr

184 and generation of electrochemical current by bead labels.

185 The resulting bead lane module, with a volume of ~3 x 10(-5) mm(3), is

186 e closed microfluidic devices in <30 s using bead lane modules inside which microbeads functionalized

187 We performed whole gut transit, bead latency, and geometric center studies.

188 cal chain stiffness and invariability of the bead length.

189 overlays a silicone membrane, separating the bead library reaction zone from a quadrupole mass analyz

190 f these tubes and show that the formation of bead-like structures along the nanotubes can result from

191 rized via fluid flow simulations and polymer bead loading tests, we trapped Aiptasia larvae containin

192 tir disc that causes chaotic mixing of glass beads ("MagVor").

193 echnique called multiplexed kinase inhibitor beads/mass spectrometry (MIB/MS), we profiled the select

194 the observed effects could be related to the bead material because the same-sized silica (SiO(2)) bea

195 ditionally, we find that approximately 5% of beads may contain detectable levels of multiple oligonuc

196 in a competitive immunoassay using magnetic bead (MB) platforms at levels as low as 66 nM.

197 for 5 more min with immuno-modified magnetic beads (MB) along with an immuno-modified signal amplifie

198 The RCPs are generated on magnetic beads (MB) and subsequently, connected via streptavidin-

199 r aptamer or antibody (Ab)-modified magnetic beads (MBs) and Ab/aptamer reporter molecules linked to

200 ed a strong correlation among single antigen bead mean fluorescence intensity and complement assays p

201 pecifically, in a cell-encapsulated alginate bead model, induced short hairpin (shRNA) knockdown or o

202 reactor of 23 cm diameter, with a 1 mm glass bead monolayer serving as a porous medium, was used to i

203 rn the tube radius, number of beads, and the bead morphology.

204 Both stator-rotor and bead motion-based homogenizing were found to result in h

205 halted inside the aster, while dynein-coated beads moved to the aster center at a constant rate, sugg

206 el allowed us to characterize conditions for bead movement and bundle buckling.

207 arious assay parameters including bead size, bead number, antibody affinity and assay time, and provi

208 al 455 (1.4%) observations failed due to low bead numbers (<20/analyte).

209 Bead occlusion and ONC retinas demonstrated significant

210 Importantly, bead occlusion and ONC retinas resulted in differential

211 of the current study utilized both chronic (bead occlusion) and acute (optic nerve crush, ONC) rat m

212 The observed effect of the PS beads on the nematodes correlated well with the total su

213 Our understanding of the beads-on-a-string arrangement of nucleosomes has been bu

214 , which was previously discovered from a one-bead-one compound (OBOC) library to inhibit Abeta(40) ag

215 n how to prepare test samples of fluorescent beads, operate this instrument to acquire images of whol

216 eterogeneous binding of analyte molecules on bead or sensor surfaces, attachment of bead labels to se

217 using NeutrAvidin or concanavalin A agarose beads or directly via covalent coupling of free amines o

218 lities were evaluated, using either magnetic beads or gold-coated glass slides decorated with cortiso

219 g any controlled-release pellets, particles, beads, or granules in any physiologically-relevant envir

220 allowed individual populations of dielectric beads overlapping in either size or RI to be clearly dis

221 tonsa-fibers (P < 0.01); H. gammarus larvae-beads (P < 0.05).

222 ormation on solute transport through a glass bead packing at different saturations.

223 ce principle to achieve single cell/barcoded bead pairing with high cell utilization efficiency (95%)

224 the single-particle level, i.e., one single bead per trapping site, on the basis of a passive hydrod

225 ated well with the total surface area of the beads per volume, with a 50% inhibition of reproduction

226 e of phase separation in DPR toxicity, a one-bead-per-amino-acid (1BPA) coarse-grained molecular dyna

227 her functional groups present in the polymer bead play an important role in adsorption but are not in

228 aser rapidly and sequentially heats catalyst beads positioned on a heat-dissipating carbon paper supp

229 The beads prepared at each step were characterized by FTIR a

230 gated zwitterionic polymer-modified magnetic beads prior to lysis and analyzed by electrochemical imp

231 rome P450 (cyt P450) enzymes on the magnetic beads provided a broad spectrum of metabolic enzymes.

232 nd tightly packed immobilization on magnetic beads, providing a highly efficient capture of the toxin

233 ombination with streptavidin coated magnetic beads, providing capture efficiencies of 90-100%.

234 Beads released high antioxidant capacity during digestio

235 d the aggregation of Dsg1/Dsc1 and Dsg3/Dsc3 beads, respectively, whereas nonpathogenic mAbs did not.

236 ited the adhesion of Dsg1/Dsc1 and Dsg3/Dsc3 beads, respectively.

237 ness than out-of-plane stresses that lead to bead rolling along the cell long axis (i.e., alignment o

238 n to Lorenz-Mie scattering theory yields the bead's position with nanometer accuracy in three dimensi

239 Twenty patients with Luminex single antigen bead (SAB) assay-defined DSA but negative complement-dep

240 renal transplantation is the single antigen bead (SAB) assay.

241 metal isotope signals from single cells and bead samples.

242 low virus recovery we observed may be due to bead saturation or hindrance by existing glycans in the

243 choice of various assay parameters including bead size, bead number, antibody affinity and assay time

244 t 55.4 +/- 12.9 cm(2)/mL, independent of the bead size.

245 were isolated from blood samples by magnetic bead sorting at the point of diagnosis and during the co

246 an dynamics method based on a coarse-grained bead-spring chain model has been proposed to compute the

247 The results identify that MUC5B has a beaded structure repeating along the polymer axis and su

248 MWG retains its unique properties within the beads, such as remediating Pd(II) and reducing it in sit

249 tes the signal-generating molecules from the bead surface.

250 lex-based actin polymerization is induced on bead surfaces in the absence of CP, we produce robust po

251 combines improvements in library generation, bead synthesis and array indexing to reach an RNA captur

252 The bead synthesis conditions were optimized to obtain micro

253 digestion-fermentation over Ca(II)-alginate beads synthesized with sugars and biopolymers.

254 with SCZ performing the same versions of the beads task.

255 d two versions of a probabilistic reasoning (beads) task, which required participants to either sampl

256 Judging from the presence of fine versus beaded terminals, the vast majority of these neurons pro

257 generated by the displacement of micron-size beads tethered by DNA probes that are between 1 and 7 mi

258 By starting with resin beads that are functionalized with benzylguanine, a seri

259 Cytokinins covalently linked to beads that could not pass the plasma membrane increased

260 t evidence of birch bark tar, art, and shell beads, the idea that Neanderthals were cognitively infer

261 sting for non-specific binding to PEG-coated beads, the mean percent recovery by H type III-coated be

262 rding to a power-law relationship and on the bead-tip distance according to a stretched exponential r

263 an unsaturated porous-medium column of glass beads to assess: (i) the release of particulate plastic

264 r microsomes (HLMs), immobilized on magnetic beads to facilitate determination of the activity of mic

265 ped poly(carboxybetaine-methacrylate) coated beads to isolate L1 cell adhesion molecule (L1CAM)-posit

266 Here, we utilized Wnt3a-beads to locally activate Wnt co-receptors.

267 The assay uses dye-encoded antigen-coated beads to quantify the levels of immunoglobulin G (IgG),

268 s9 R-loop formation and collapse using rotor bead tracking (RBT), a single-molecule technique that ca

269 Real-time multiplexed bead tracking therefore requires a more efficient tracki

270 ive 3D phasor algorithm that provides robust bead tracking with nanometric localization accuracy in a

271 bustness can improve multiplexed biophysical bead-tracking applications, especially when high through

272 The large-scale microfluidic single-bead trapping permits massively multiplexed fluorescence

273 Metal ion leaching from the beads under storage and application conditions was also

274 The analytes bind to the hydrophilic beads upon the addition of organic solvent, and various

275 cytes, as shown by live imaging of AT, 45-um bead uptake ex vivo, and higher lipid content in vivo.

276 clusively due to phagocytosis of stimulation beads used in cocultures and absent when using soluble o

277 platform, named Paired-seq, with high cells/beads utilization efficiency, cell-free RNAs removal cap

278 main features: deep hemorrhages (DH), venous beading (VB), and intraretinal microvascular abnormaliti

279 rget exosomes were firstly captured by latex beads via aldimine condensation, followed by bio-recogni

280 e mean percent recovery by H type III-coated beads was 308.11% +/- 861.61.

281 Moreover, the morphology of formulated beads was examined using a scanning electron microscope

282 termed SpliMLiB for Split-and-Mix Library on Beads-was applied towards the directed evolution of an a

283 various grape-sized fruit and hydrogel water beads, we demonstrate that the formation of plasma is du

284 Further, by combining magnet beads, we established a rapid and wash-free homogeneous

285 R2, MSP23D7, MSP119k, and PfRh2-2030 coupled beads were significantly associated with a higher probab

286 Negatively charged, 500 nm latex beads were used in multiple-particle tracking experiment

287 ral infection followed by death; fluorescent beads were used to demonstrate that particles may indeed

288 ace after enzyme immobilization on the glass bead, which seemed to be related to the polyaldehyde kef

289 vents of immunoglobulin-G-coated polystyrene beads, which are held in an optical trap near the cell m

290 g imaging, below the equatorial plane of the beads, which is known as the CONA technique.

291 tection and quantification of the individual beads, which prevents the optical interfering of backgro

292 protected by Cappuccino, grow away from the beads while pointed ends are retained, as expected for n

293 lear empty cavities in the plain Ca-alginate-beads, while CTX-OCT-Alg showed occupied beads without c

294 the microtubule due to contact of the single bead with the underlying microtubule.

295 Zimm mode analysis confirms the existence of beads with a finite length that corresponds to a reduced

296 solid-phase reversible immobilization (SPRI) beads with protein-denaturing buffers, and then identifi

297 In the case of ion-exchange chromatographic beads with small, tortuous pores, where the existence of

298 The targets are made by coating glass beads with supported lipid bilayers followed by coupling

299 onfunctionalized carboxylate coated magnetic beads without affinity ligands.

300 ate-beads, while CTX-OCT-Alg showed occupied beads without cavities.