ライフサイエンスコーパス: benign tumor

1 specific (and may, in fact, also be found in benign tumors).

2 more strongly expressed in malignant versus benign tumors.

3 sion in anaplastic meningiomas compared with benign tumors.

4 ned from normal brain tissue or low grade or benign tumors.

5 ment of one of the most common kind of human benign tumors.

6 any of 65 malignant, five borderline or six benign tumors.

7 n uterine leiomyomata and a variety of other benign tumors.

8 l tumors showed LOH in contrast to only 1/25 benign tumors.

9 wth, vascular malformations (VMs), cysts and benign tumors.

10 zed extracellular matrix, resulting in rigid benign tumors.

11 and are also useful for assessing growth of benign tumors.

12 ne expression differed markedly in OC versus benign tumors.

13 Neurofibromas are NF1-associated benign tumors.

14 dromes are characterized by highly penetrant benign tumors.

15 is, whereas more wavy bundles correlate with benign tumors.

16 the basis of clinical trials for RAS-driven benign tumors.

17 esions and reduce surgical interventions for benign tumors.

18 igenetic modifiers DNMT3A and BCOR in 29% of benign tumors.

19 rodevelopmental deficits and the presence of benign tumors.

20 20 (13.6%) were classified as having unknown benign tumors.

21 ences in contrast to no or low expression in benign tumors.

22 has a role in the genesis and progression of benign tumors.

23 nonneuroendocrine origin, and 7 patients had benign tumors.

24 n the SUVmax of (18)F-FDOPA in malignant and benign tumors.

25 tion analysis helped separate malignant from benign tumors.

26 SM overestimates k(ep), particularly for the benign tumors.

27 uppression that restricts the progression of benign tumors.

28 imit of mean redistribution rate constant in benign tumors (0.88 minutes(-1)) and the volume of cance

29 MI displacement (1.1 +/- 0.5 um) compared to benign tumors (3.6 +/- 1.5 um) and the adjacent non-canc

30 patients (38%) had malignant tumors, 42 had benign tumors (37%), and 29 (25%) had nonneoplastic lesi

31 = .022) and abdominal pain in patients with benign tumors (45% vs 25%, respectively, P = .025).

32 (i) a pilot set of 100 women with OC (50) or benign tumor (50), and (ii) an independent set of 118 wo

33 esenchymal hamartoma of the liver (MHL) is a benign tumor affecting children that is characterized by

34 as associated with a decreased risk of these benign tumors (age- and hospital-adjusted odds ratio = 0

35 ple tumor syndrome in which patients develop benign tumors along peripheral nerves throughout the bod

36 The mean age at detection was 11 years for benign tumors and 14 years for malignant tumors (P = .00

37 ved S100A8 expression in melanoma but not in benign tumors and confirmed the same pattern for S100A8'

38 ncogenic BRAF(V600E) elicited many more such benign tumors and did so more rapidly than KRAS(G12D).

39 is associated with the development of mostly benign tumors and focal dysplasias.

40 20 are both expressed differentially between benign tumors and invasive EOC, and between borderline/L

41 By comparison, all vascular areas in benign tumors and low-stage cancers were endothelial lin

42 s mutations have been identified in multiple benign tumors and malignant cancers.

43 Further studies inclusive of benign tumors and non-breast malignancies are warranted.

44 in malignant tumors and the lowest uptake in benign tumors and normal mammary tissue.

45 vities were also observed in EOC compared to benign tumors and normal tissues.

46 tin than tissue samples from 6 patients with benign tumors and samples of healthy ovarian epithelium

47 hat deregulation of growth control occurs in benign tumors and that subsequent mutations not involved

48 basal craniotomy is well established in both benign tumors and vascular lesions, but has only limited

49 history of tumors, 23,282 had a history of a benign tumor, and 973 had a history of malignancy.

50 , to pilocytic astrocytoma (PA), a primarily benign tumor, and find highly different NCCM frequencies

51 , 6 of 6 low malignant potential, 5 of the 6 benign tumors, and 9 of 10 normal patient samples.

52 ow malignant potential (LMP) tumors, 16 with benign tumors, and a separate validation group of 39 wom

53 opment of multiple mucocutaneous lesions and benign tumors, and enhanced cancer predisposition.

54 sion in malignant human tumors compared with benign tumors, and increased expression correlates stron

55 stic, 45% (70 of 157) were dermoids or other benign tumors, and less than 1% (one of 157) were malign

56 itical role in many diseases such as cancer, benign tumors, and macular degeneration.

57 kidney, TSC presents with the enlargement of benign tumors (angiomyolipomata) and cysts, which eventu

58 Benign tumors are often amenable to surgical excision, w

59 These benign tumors are sensitive to inhibition by ATP-competi

60 These benign tumors are typically composed of adipose cells in

61 Ganglioneuroma (GN) is a rare benign tumor arising from the neural crest cells.

62 of bilateral acoustic schwannomas and other benign tumors associated with the central nervous system

63 l as the differentiation of malignant versus benign tumors based on absolute labeling uptake.

64 Neurofibromas are NF1-associated benign tumors but can cause substantial discomfort and d

65 as were more often seen in malignant than in benign tumors, but the difference was not statistically

66 (n=38) to potentially reduce the referral of benign tumors by 65% without missing melanoma.

67 Laryngeal papillomas are benign tumors caused by human papillomaviruses types 6 a

68 vated in phenotypically normal or relatively benign tumor cells by experimentally increasing HA produ

69 Uterine leiomyomata are one of several benign tumors characterized by frequent chromosomal rear

70 Uterine leiomyomas or fibroids (UFs) are benign tumors characterized by hyperplastic smooth muscl

71 arcinomas to oncocytomas-rare, predominantly benign tumors characterized by the accumulation of defec

72 y samples from human adrenal myelolipomas, a benign tumor composed of adipose and hematopoietic tissu

73 acterized by the formation of neurofibromas, benign tumors composed mainly of Schwann cells, which ca

74 Neurofibromas are benign tumors comprised primarily of Schwann cells and f

75 ic value when used to differentiate EOC from benign tumor control samples with an area under the curv

76 ered from that in nontransgenic mice in that benign tumors converted from exophytic to endophytic pap

77 ogeneous group of tumors that encompass both benign tumors cured with surgical resection and highly l

78 umors (e.g., neurofibrosarcomas) compared to benign tumors (cutaneous neurofibromas).

79 tiation and AP-1 activation while decreasing benign tumor development and malignant progression.

80 rio, Canada, until the earliest of cancer or benign-tumor diagnosis, death, end of health care covera

81 Hepatocellular adenomas (HCAs) are rare benign tumors divided into three main subgroups defined

82 ortalization, and metastatic spread, whereas benign tumors do not express gene products that mediate

83 carcinogenesis that lead to the formation of benign tumors, E6 primarily contributes to the late stag

84 mas, 9 follicular thyroid carcinomas, and 26 benign tumors (follicular adenomas and hyperplastic nodu

85 ominant disorder characterized by widespread benign tumor formation in a variety of organs.

86 om our laboratory and others have shown that benign tumor formation in Nf1 genetically engineered mic

87 yte responses to oncogenic ras in culture or benign tumor formation in nude mouse grafts, disruption

88 Twenty-six % of informative benign tumors (four follicular adenomas and three Hurthl

89 What restrains benign tumors from overexpressing tumor-associated prote

90 ncer but not in the VECs (or tumor cells) of benign tumors from ten patients with fibrocystic disease

91 e (83%) of six patients with premalignant or benign tumors had a premalignant condition (cryptochydis

92 None of the benign tumors had CDKN2A/p16 deletions, whereas three of

93 Loss of fak induced once benign tumors had formed inhibited malignant progression

94 nflammatory and cardiovascular diseases, and benign tumors had increased false-positive test results

95 l dominant disorder that is characterized by benign tumors (hamartomas and hamartias) involving multi

96 dition in which affected individuals develop benign tumors (hamartomas) in many organs.

97 ous sclerosis (TSC), in which development of benign tumors, hamartomas, occurs via a two-hit mechanis

98 eadily separates malignant from atypical and benign tumors, implicating that DNA methylation patterns

99 Uterine leiomyoma is the most common benign tumor in reproductive-age women.

100 iated with the development of hamartomas and benign tumors in a variety of tissues, including the ski

101 d prostate overexpressed HIF-1alpha, whereas benign tumors in breast and uterus did not.

102 antile hemangiomas (IHs) are the most common benign tumors in early childhood.

103 t that in contrast to the narrow spectrum of benign tumors in human NF2 patients, Nf2 heterozygous mi

104 rial networks and diagnosis of malignant and benign tumors in liver tissues via densely connected con

105 human cancers, we hypothesized that the more benign tumors in mice expressing E7 would be distinct fr

106 d with independently induced SCC relative to benign tumors in mouse skin.

107 d may help explain the diverse nature of the benign tumors in multiple endocrine neoplasia type 1.

108 a tumor suppressor syndrome characterized by benign tumors in multiple organs, including the brain an

109 disorder characterized by the appearance of benign tumors in multiple organs, including the heart.

110 nt disorder that leads to the development of benign tumors in multiple organs.

111 s a rare autosomal dominant disorder causing benign tumors in the brain and other vital organs.

112 nd even superior technique for management of benign tumors in the deep parotid lobe.

113 fficient to cause oncogenic Ras(V12)-induced benign tumors in the developing eye to exhibit metastati

114 While benign tumors in the heart, lungs, kidney, and brain are

115 Parathyroid adenomas are benign tumors in the parathyroid glands, whose pathogene

116 ying (TA) cells, are unable to generate even benign tumors in the same genetic context.

117 Activation of mTOR promotes the formation of benign tumors in various organs and the mechanisms under

118 Notably, malignant, but not benign, tumors induce peripheral wasting.

119 er, despite differences in the efficiency of benign tumor induction, only mice with lung epithelium e

120 ch as HPV-11, which cause the development of benign tumors, interacts with the cellular E3 ubiquitin

121 pigenetic event required for conversion of a benign tumor into a malignant one, thereby explaining wh

122 and familial schwannomatosis, with adulthood benign tumors involving cranial and peripheral nerves.

123 Detection of rare metastatic cells within a benign tumor is a key challenge to diagnose the cancerou

124 ignant tumors, but the role of stem cells in benign tumors is not well understood.

125 asma cell granulomas (pseudotumors) are rare benign, tumor-like proliferations composed chiefly of pl

126 freckles of PJS patients are actually small, benign tumors, LKB1/STK11 mutations must provide these l

127 38 patients had benign tumors (LR1 = 19 and LR2 = 19), 19 patients had i

128 Benign tumors (mainly leiomyoma being the most frequent

129 Describing the heterogeneity of these benign tumors may assist in predicting clinical outcomes

130 Bell palsy (n = 1397), benign tumor (n = 980), and infection (n = 257) were the

131 tases (N = 42), biliary cancer (N = 20), and benign tumors (N = 176).

132 with ovarian cancer (n = 109), patients with benign tumors (n = 19), and healthy donors (n = 56) were

133 For all malignancies and benign tumors ("neoplasms," excluding type Ir pleuropulm

134 Loss of TSC2 results in benign tumors, neurological disorders, and angiomyolipom

135 history of tumors, those with a history of a benign tumor (nonmalignant tumor with functional impairm

136 the development of lipomas, the most common benign tumor of soft tissue.

137 We characterize a novel benign tumor of the INL that, in 2 patients, was associa

138 y, DNA damage in Lisch nodule pathogenesis, "benign tumor of the iris," not "hamartoma," may be a bet

139 Synovial hemangioma is benign tumor of the joints and is seen relatively rare.

140 hepatic vascular cavernomas, the most common benign tumor of the liver, were described in the mid-180

141 Infantile hemangiomas are the most common benign tumors of infancy and childhood with a reported i

142 Infantile hemangiomas (IHs) are common benign tumors of infancy that have the potential to inte

143 gene have frequently been detected in human benign tumors of mesenchymal origin, including lipomas.

144 ons in the cylindromatosis (CYLD) gene cause benign tumors of skin appendages, referred to as cylindr

145 Aldosterone-producing adenomas (APAs) are benign tumors of the adrenal gland that constitutively p

146 an include seizures, mental retardation, and benign tumors of the brain, skin, heart, and kidneys.

147 Benign tumors of the breast and uterus, both of which ar

148 Keloids are benign tumors of the dermis that form during a protracte

149 ed autosomal genodermatosis characterized by benign tumors of the hair follicle, has been associated

150 drome, a hamartoma disorder characterized by benign tumors of the hair follicle, lung cysts, and rena

151 Hemangiomas are one of the common primary benign tumors of the intraosseous and soft tissue compar

152 Angiomyolipomas are benign tumors of the kidney derived from putative periva

153 e urogenital system tumors, including mostly benign tumors of the ovary and uterus, and adrenal adeno

154 Neurofibromas are benign tumors of the peripheral nerve sheath, which occu

155 Plexiform neurofibromas (PNFs) are benign tumors of the peripheral nervous system that repr

156 Cutaneous neurofibromas (cNFs) are benign tumors of the skin that affect >95% of adults wit

157 terized by seizures, mental retardation, and benign tumors of the skin, brain, heart, and kidneys.

158 Uterine fibroids, benign tumors of the smooth muscle layer of the uterus,

159 Uterine leiomyomata, or fibroids, are benign tumors of the uterine myometrium that significant

160 r fibroids are highly heritable, common, and benign tumors of the uterus with poorly understood etiol

161 Hemangiomas are benign tumors of the vascular endothelium and are the mo

162 Infantile hemangiomas are benign tumors of vascular endothelial cells (ECs), chara

163 significantly associated with female gender, benign tumor on frozen section biopsy, and postoperative

164 found in the cyst fluids of 18 patients with benign tumors or non-neoplastic cysts.

165 to malignant tumors versus those arising in benign tumors or shared with normal tissues.

166 neoplasms but not in normal uterine tissue, benign tumors, or most low-grade neoplasms.

167 Cutaneous leiomyomas, rare benign tumors originating from the arrector pili muscle

168 ents after complete and partial resection in benign tumors other than myxomas.

169 fore carcinogen exposure strongly suppressed benign tumor (papilloma) formation, and that the few, sm

170 We now demonstrate that wounding induces benign tumors (papillomas and keratoacanthomas) in InvEE

171 on of TGF-beta signaling in MSCs governs the benign tumor phenotype in OF and highlight TGF-beta sign

172 evelopmental trajectory, resulting in a more benign tumor phenotype.

173 pid phosphatase activity can promote cancer, benign tumors (PHTS), and neurodevelopmental disorders (

174 This benign tumor rarely transforms into conjunctival melanom

175 These benign tumors represent clonal hyperproliferation of mel

176 Initially described for peripheral, benign tumors resected by nonanatomic wedge resections,

177 ) oncoprotein kinase initiates the growth of benign tumors retaining characteristics of their cell of

178 for ODP were PDAC (OR: 0.45, CI: 0.31-0.64), benign tumor size >5 centimeters (OR: 0.40, CI: 0.23-0.6

179 =0.0003), lipomas (SMR 5.0, P=0.0003), other benign tumors (SMR 4.63, P=0.003), and malignant tumors

180 tion of mitotic APC/C substrates not seen in benign tumors, suggesting that a "mitotic profile" in tu

181 ly increase the malignant conversion rate of benign tumors, suggesting that inhibition of apoptosis c

182 th different DNMT3A mutations exist in these benign tumors, suggesting that intra-tumor heterogeneity

183 Mdm2 amplification in benign tumors suggests that it is not sufficient for p53

184 TOR signaling and consequently causes TSC, a benign tumor syndrome affecting multiple organs.

185 Tuberous sclerosis is a largely benign tumor syndrome derived from the acquisition of so

186 Our results suggest that PJS and other benign tumor syndromes could be caused by dysregulation

187 hers syndrome (PJS) are dominantly inherited benign tumor syndromes that share striking histopatholog

188 ast two evaluable section cores per case) in benign tumors than in invasive EOC, whereas there were m

189 d Harderian (lachrymal) gland hyperplasia, a benign tumor that does not progress to frank malignancy.

190 NF is a rare benign tumor that infrequently presents in the periorbit

191 raepithelial neoplasia (BilIN) is the common benign tumor that is suspected to be precancerous lesion

192 Hamartoma of the thoracic wall is a rare benign tumor that occurs in infancy and can be mistaken

193 eous neurofibromas (cNFs) are NF1-associated benign tumors that affect nearly 100% of patients with N

194 Plexiform neurofibromas are slow growing benign tumors that are highly vascular and can progress

195 t is characterized by the growth of multiple benign tumors that are often difficult to treat.

196 Schwannomas are benign tumors that arise from Schwann cells of the nerve

197 iated with bilateral vestibular schwannomas, benign tumors that arise from the eighth cranial nerve.

198 Uterine leiomyomas (UL) are benign tumors that arise in the myometrial layer of the

199 on of malignant tissue and suggest that some benign tumors that become cancerous may have genetic abe

200 Uterine leiomyomas are benign tumors that can cause pain, bleeding, and inferti

201 Uterine fibroids are benign tumors that can cause severe symptoms.

202 The 2 benign tumors that did not express the VPAC1 receptor we

203 CNFs are benign tumors that exhibit cellular and molecular hetero

204 Vestibular schwannomas (VS) are benign tumors that lead to significant neurologic and ot

205 Cutaneous neurofibromas (CNFs) are benign tumors that occur in the dermis of individuals wi

206 der leading to the widespread development of benign tumors that often contain giant cells.

207 Compared to the benign tumors, the atypical and malignant meningiomas de

208 ch as P27KIP1 for malignant, borderline, and benign tumors, there was a significant difference betwee

209 It takes approximately 17 years for a large benign tumor to evolve into an advanced cancer but <2 ye

210 step involved in the malignant conversion of benign tumors to frank cancer.

211 ng promote progression of BRAF(V600E)-driven benign tumors to malignant adenocarcinoma.

212 low-up investigation of 24 cancers and three benign tumor types showed that PTPN14 loss-of-function v

213 eoperative fine-needle aspiration (91.8%), a benign tumor was diagnosed; 5 of these patients (3.2%; 9

214 The mean latency period for benign tumors was longer than that for malignant lesions

215 Although a history of benign tumors was not associated with an increased ESKD

216 In benign tumors, we defined three levels of ss-catenin act

217 Hippocampal sclerosis and benign tumors were associated with better outcomes relat

218 ent were broadly overrepresented in the more benign tumors, whereas genes involved in RNA processing

219 crocalcifications are associated mainly with benign tumors, whereas type II microcalcifications are p

220 seen with neurological processes, including benign tumors, which are treatable.

221 umorigenesis, by accelerating development of benign tumors while restraining further progression to m

222 events involved in the pathobiology of these benign tumors will provide a basis for understanding the

223 emonstration of widespread distribution of a benign tumor with limited proliferative capability indic

224 Furthermore, RED differentiated cancers from benign tumors with an overall accuracy of 90% (27 of 30)

225 conjunctival tumors in children by comparing benign tumors with their malignant counterparts.

226 ters that best differentiated malignant from benign tumors, with a typical prolonged washout observed

227 in human neuroblastoma tumors compared with benign tumors, with loss correlating with decreased surv