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1 er inhibiting also butyrylcholinesterase and beta-glucosidase.
2 e, soluble beta-glucosidase and GPI-anchored beta-glucosidase.
3 glyceraldehyde-3-phosphate dehydrogenase and beta-glucosidase.
4 obiose, which can be converted to glucose by beta-glucosidase.
5 es was evaluated with beta-galactosidase and beta-glucosidase.
6 ecific and multivalent interaction with acid beta-glucosidase.
7 n was found to be dependent on the bacterial beta-glucosidase.
8 elated with their activation effects on acid beta-glucosidase.
9 ort the identification of the H antigen as a beta-glucosidase.
10 nt activity of the lysosomal hydrolase, acid beta-glucosidase.
11 i = 8.2 nM) of the Thermotoga maritima TmGH1 beta-glucosidase.
12 of the aglycones produced by hydrolysis with beta-glucosidase.
13 n of the beetle myrosinase from other insect beta-glucosidases.
14 d has up to 76% sequence similarity to other beta-glucosidases.
15 ously for other glycoside hydrolase family 3 beta-glucosidases.
16 valently modify the nucleophile of retaining beta-glucosidases.
17 e of 4.55, as found for most of the fungi of beta-glucosidases.
18 transcription factors, ABC transporters, and beta-glucosidases.
19 glutamates that play catalytic roles in the beta-glucosidases.
20 ated sequence homology with genes for fungal beta-glucosidases.
21 including endoglucanases, exoglucanases, and beta-glucosidases.
22 d to interpret the glucose dependence of GH1 beta-glucosidases.
23 s to understand the glucose tolerance in GH3 beta-glucosidases.
24 ctosidase (3.42), beta-xylosidase (0.07) and beta-glucosidase (0.28) on low-cost copra meal (CM) in S
25 the salvage pathway involving, in part, acid beta-glucosidase 1 (GBA1), which cleaves glucosylceramid
26 the present study, we examined whether acid beta-glucosidase 1 (GBA1), which hydrolyzes glucosylcera
29 d and purified as follows: broad specificity beta-glucosidase 1460-fold and pyridoxine-beta-D-glucosi
39 ceramide; the same reaction catalyzed by the beta-glucosidase acid 1 (GBA1) defective in subjects wit
40 of 70.2-380.9 nM in various cancer cells by beta-glucosidase activation inside of the tumor cells, w
42 says revealed marked differences in secreted beta-glucosidase activities from three H. capsulatum res
50 8.3 and 17 muM, and also inhibited lysosomal beta-glucosidase activity in live cells at low-micromola
52 H. capsulatum culture supernatants revealed beta-glucosidase activity near the predicted mobility of
60 CWEC, CWEN, and enzyme activities especially beta-Glucosidase activity were the key determinants of M
61 beta-glucosidase enzymes (Delta3betaG) lacks beta-glucosidase activity, but efficiently induces cellu
62 and one intracellular beta-glucosidase lacks beta-glucosidase activity, but efficiently induces cellu
63 data indicated that the null genotypes have beta-glucosidase activity, but the enzyme occurs as inso
64 f salicin and d-arabinose, and expression of beta-glucosidase activity, correctly assigned each strai
68 of detergent-independent membrane-associated beta-glucosidase activity; 3) was more variable among mo
70 ally interacts with a chimeric lectin called beta-glucosidase aggregating factor (BGAF), resulting in
75 protein, and BGAF is solely responsible for beta-glucosidase aggregation and insolubility and, thus,
76 neurodegenerative course had two novel acid beta-glucosidase alleles: a complex, maternally derived
77 GE by the endoplasmic reticulum and vacuolar beta-glucosidases allows the rapid formation of free ABA
79 ted against several glycosidases (alpha- and beta-glucosidase, alpha- and beta-galactosidase, alpha-
82 to compare the levels of phenolic compounds, beta-Glucosidase and antioxidant activity during the age
83 ehave as selective competitive inhibitors of beta-glucosidase and are promising candidates as pharmac
84 imental design to optimise the production of beta-glucosidase and convert glycosidic isoflavones in a
85 tural green olives is due to the activity of beta-glucosidase and esterase during the first months of
88 is a 35-kD protein and binds specifically to beta-glucosidase and renders it insoluble during extract
89 based on sequence differences between maize beta-glucosidase and sorghum beta-glucosidase (dhurrinas
90 howed 54 and 48% identities to raucaffricine beta-glucosidase and strictosidine beta-glucosidase, res
91 GH161 genes co-localize with genes encoding beta-glucosidases and ATP-binding cassette transporters,
92 pe, and it specifically interacts with maize beta-glucosidases and forms large insoluble aggregates.
93 olved in forming a site for binding to maize beta-glucosidases and thus provides a plausible explanat
95 this study was to monitor olive hydrolytic (beta-glucosidase) and oxidative (peroxydase, POX, and po
96 ency in glucocerebrosidase (GBA, a retaining beta-glucosidase), and deficiency in GBA constitutes the
97 Conduritol B epoxide is an inhibitor of acid beta-glucosidase, and lowers glucosylceramide degradatio
98 ars exhibited specificity for almond-derived beta-glucosidase, and the 1-nonylazetidine 25 inhibited
99 ineered strains express cellulase, xylanase, beta-glucosidase, and xylobiosidase enzymes under contro
103 to interact directly with the substrates in beta-glucosidases are not conserved in hydroxyisourate h
105 describes novel preparations of immobilized beta-glucosidase as highly stable and active catalysts f
106 The x-ray structure of N370S mutant acid beta-glucosidase at acidic and neutral pH values indicat
107 -deoxy-2-fluoro-beta-glucosides react with a beta-glucosidase at rates differing by 10(6)-fold, despi
109 gions to BGAF binding, we constructed mutant beta-glucosidases based on sequence differences between
112 -glucur) are both produced by E. coli, while beta-glucosidase (beta-gluco) is produced by Enterococcu
113 in cell wall metabolism (beta-galactosidase, beta-glucosidase, beta-amylase, chitinase, pectate lyase
117 Four glycosidases, alpha-glucosidase (AG), beta-glucosidase (BG), beta-xylosidase (BX), cellobiohyd
118 nced potential activities of cellulase (CL), beta-glucosidase (BG), lignin peroxidase (LiP), and mang
119 mnosperms) against the potential activity of beta-glucosidase (BG), N-acetyl-glucosaminidase (NAG), a
121 acterize a family 3 glycosyl hydrolase (GH3) beta-glucosidase (Bgl) produced by Malbranchea pulchella
122 obacco (Nicotiana tabacum) plants expressing beta-glucosidase (Bgl-1) show modified development.
123 is end, we designed a chimeric cohesin-fused beta-glucosidase (BglA-CohII) that binds directly to the
125 n to be in an operon with a putative phospho-beta-glucosidase (bglB) downstream and a predicted antit
127 in of BGAF is responsible for its lectin and beta-glucosidase binding and aggregating activities.
130 sists primarily of stereochemistry-retaining beta-glucosidases but also contains a subfamily of beta-
131 structural basis of glucose tolerance in GH1 beta-glucosidases but also demonstrate a strategy to imp
132 rabidopsis thaliana contain large amounts of beta-glucosidases, but the physiological functions of ER
134 dentify both catalytic residues of retaining beta-glucosidases by the combined use of cyclophellitol
135 l glucopyranoside hydrolysis by sweet almond beta-glucosidase can be generated based on 24 time-cours
136 ar enzymes of intact heterotrophic biofilms, beta-glucosidase (carbon-cycling) and l-leucin aminopept
138 ed it to non-homologous (putative) retaining beta-glucosidases categorized in GH1 and GH116: GBA2, GB
139 stine, spleen and kidney contain a cytosolic beta-glucosidase (CBG) that hydrolyses various beta-d-gl
141 which is encoded by an operon with a phospho-beta-glucosidase (CelA) and a cellobiose-specific sugar
142 i has been cloned, and the encoded 6-phospho-beta-glucosidase (cellobiose-6-phosphate [6P] hydrolase;
144 n mutant had increased expression of several beta-glucosidases, consistent with known inhibition of b
145 ization of both enzymes, as a membrane-bound beta-glucosidase could specifically digest soluble xylog
147 jCel3A is, thus, preferable as an industrial beta-glucosidase despite its lower activity caused by tr
148 s between maize beta-glucosidase and sorghum beta-glucosidase (dhurrinase 2, Dhr2), which does not bi
149 nd Gu2, to which BGAF binds, and the sorghum beta-glucosidase (dhurrinase) isozyme Dhr1, to which BGA
151 In certain maize genotypes, called "null," beta-glucosidase does not enter gels and therefore canno
153 d utilises the diglycosidase alpha-rhamnosyl-beta-glucosidase (EC 3.2.1.168) to quantitatively hydrol
156 ein from the native expression system showed beta-glucosidase enzymatic activity in substrate gels an
157 ts of the beta-glucoside permease (bglP) and beta-glucosidase enzyme (bglB) in 5448, we showed that b
159 concentrations were associated with enhanced beta-glucosidase enzyme activities (V max ) but short-te
160 lasmid pMAD401 displayed increased levels of beta-glucosidase enzyme activity and H protein expressio
161 determine whether H. capsulatum contained a beta-glucosidase enzyme activity and whether this activi
162 nhibitors of glucocerebrosidase (GCase), the beta-glucosidase enzyme deficient in Gaucher disease (GD
163 enzymatic activities, results show that the beta-glucosidase enzyme is the key enzyme responsible fo
165 N. crassa mutant carrying deletions of three beta-glucosidase enzymes (Delta3betaG) lacks beta-glucos
166 re, a mutant lacking genes encoding both the beta-glucosidase enzymes and cellodextrin transporters (
167 eletions of two genes encoding extracellular beta-glucosidase enzymes and one intracellular beta-gluc
169 cells through the action of an intracellular beta-glucosidase following import by a high-affinity cel
172 hydrolysis of the sugar moiety by intestinal beta-glucosidases for uptake to the peripheral circulati
173 enzyme and the immobilised cells containing beta-glucosidase, for 2h at 40 degrees C, promoted effic
174 es were assayed to catalyze the process, and beta-glucosidase from Aspergillus niger was selected.
177 gous expressed OeGLU, an oleuropein-specific beta-glucosidase from olive (Olea europaea), had enzymat
178 egions were fused to the bglC ORF encoding a beta-glucosidase from the thermophilic bacterium Thermob
179 different Arabidopsis (Arabidopsis thaliana) beta-glucosidases from glycoside hydrolase family 3.
180 tivity of the industrially relevant family 3 beta-glucosidases from Hypocrea jecorina, HjCel3A and Hj
181 validated the method by using the retaining beta-glucosidase GBA (CAZy glycosylhydrolase family GH30
184 beta-glucosidase GBA1 and the non-lysosomal beta-glucosidase GBA2 degrade glucosylceramide (GlcCer)
185 a-epoxide (CBE), as well as the nonlysosomal beta-glucosidase (GBA2) inhibitor N-butyldeoxygalactonoj
189 , is caused by insufficient activity of acid beta-glucosidase (GCase) and the resultant glucosylceram
193 del (CBE-N2a) was created by inhibiting acid beta-glucosidase (GCase) in N2a cells with conduritol B
196 somal sphingolipid degradation pathway, acid beta-glucosidase (GCase) requires saposin C for optimal
197 se is caused by mutations in the enzyme acid beta-glucosidase (GCase), the most common of which is th
202 tic patients with Gaucher disease (GD) (acid beta-glucosidase [Gcase] deficiency) are treated with in
203 n Enterococcus faecalis, encodes a 6-phospho-beta-glucosidase (GenA) and a phosphotransferase system
204 ritance reported for the null alleles at the beta-glucosidase gene is actually for the BGAF protein,
205 order caused by deficiency in lysosomal acid beta-glucosidase (GlcCerase), the enzyme responsible for
208 improved the functional properties of a GH1 beta-glucosidase highly expressed by Trichoderma harzian
209 addition of exogenous noncellulosomal enzyme beta-glucosidase; however, because the cellulosome is ad
211 Here we show that PYK10, the most abundant beta-glucosidase in A. thaliana root ER bodies, hydrolyz
212 estigate the possible role of a brush border beta-glucosidase in the hydrolysis of PNG, lactase phlor
215 propyl" analogue would be a potent retaining beta-glucosidase inhibitor for those enzymes reacting th
216 ophellitol aziridine-both covalent retaining beta-glucosidase inhibitors-we postulated that the corre
222 lpha-galactosidase, and cellobiose-inducible beta-glucosidase is unaffected in the ccpA strain, sugge
223 onicus found that only one of four predicted beta-glucosidases is required in a physiological context
225 oside), whereas its close homolog, the maize beta-glucosidase isoenzyme Glu1, which shares 72% sequen
226 ave any effect on the binding of BGAF to the beta-glucosidase isozyme 1 (Glu1), and the BGAF-Glu1 com
227 y-1,4-benzoxaxin-3-one), whereas the sorghum beta-glucosidase isozyme Dhr1 (SbDhr1) hydrolyzes exclus
228 -1,4-benzoxazin-3-on e), whereas the sorghum beta-glucosidase isozyme Dhr1 hydrolyzes exclusively its
230 1-T29, E50-N127, and F466-A512) on the maize beta-glucosidase isozyme Glu1 are involved in interactio
232 enzymes by domain swapping between the maize beta-glucosidase isozymes Glu1 and Gu2, to which BGAF bi
233 r hydrological legacy alters the response of beta-glucosidase kinetics (i.e. type of inhibition) to s
234 ta-glucosidase enzymes and one intracellular beta-glucosidase lacks beta-glucosidase activity, but ef
235 mber of this family ( At3g06510; sfr2 ) is a beta -glucosidase-like gene that belongs to a distinct l
236 an M20b peptidase-like protein, and SLW3, a beta-glucosidase-like protein, in defense and the leaf-s
237 abolite repressor gene, cre-1, in the triple beta-glucosidase mutant resulted in a strain that produc
238 distinct subtypes result from different acid beta-glucosidase mutations encoding enzymes with absent
239 dicted protein sequence displays homology to beta-glucosidases of other organisms, but a recombinant
241 the screen, and the Exg1 gene (coding for a beta-glucosidase) of D. bruxellensis was cloned and puri
242 studies have also suggested that the 120-kDa beta-glucosidase participates in wall modification durin
243 st the insect but can be cleaved by a spruce beta-glucosidase, PgbetaGLU-1, which releases the active
244 tive surfaces with OM inputs had the highest beta-glucosidase, phosphatase, NAGase and cellobiohydrol
247 data support our hypothesis that the 120-kDa beta-glucosidase plays a morphogenetic role in the paras
248 The ability of olive endogenous enzymes beta-glucosidase, polyphenol oxidase (PPO) and peroxidas
250 breakdown of beta-1, 4-glycosidic linkages, beta-glucosidases produce free fermentable glucose and a
251 astomic plants as a vehicle for heterologous beta-glucosidase production for the cellulosic ethanol i
253 nternal sequences obtained from the purified beta-glucosidase protein, and a motif resembling plant s
254 ucose, and benzaldehyde by the action of the beta-glucosidase prunasin hydrolase (PH) and mandeloniti
256 celery leaves was resistant to conversion by beta-glucosidase-rich ingredients, but was converted to
257 ther) derivatives are substrates for phospho-beta-glucosidase(s) belonging to Families 1 and 4 of the
258 pite this benefit, most characterised fungal beta-glucosidases show weak activity at high glucose con
259 ich was confirmed by 3-fold inhibition using beta-glucosidase specific inhibitor [2,5-dihydroxymethy-
261 a two-component defense system comprising a beta-glucosidase that activates oleuropein into a toxic
262 iscovered was JMB19063, a novel three-domain beta-glucosidase that belongs to the GH3 (glycoside hydr
263 azinoid-specific UDP-glucosyltransferase and beta-glucosidase that catalyze the enzymatic functions r
265 we propose to redefine GBA2 activity as the beta-glucosidase that is sensitive to inhibition by N-bu
267 ,6-beta-glucanase, BT3312, and a periplasmic beta-glucosidase that targets primarily 1,6-beta-glucans
268 ibition by mechanism-based inhibitors of GH1 beta-glucosidases that utilize a double displacement ret
269 Compared with the broad specificity maize beta-glucosidase, this different binding mode explains t
271 e nutrients involves the action of 6-phospho-beta-glucosidase to convert them into usable monosacchar
273 e final enzymatic step uses laminarinase and beta-glucosidase to release the remaining beta-1,3-gluca
274 e (gluc78) encoding an antifungal glucan 1,3-beta-glucosidase was cloned from strain P1 of the biocon
276 the presence of active polyphenoloxidase and beta-glucosidase was determined by HPLC and UV-Visible s
277 The activity of pectin methyl esterase and beta-glucosidase was enhanced in ET-treated berry skins,
282 ubstrate specificity further, eight chimeric beta-glucosidases were constructed by replacing peptide
284 ism of substrate specificity further, mutant beta-glucosidases were generated by replacing Phe198, Ph
285 athepsin A (PPCA), neuraminidase (Neu1), and beta-glucosidase, were readily taken up and restored lys
286 rying mutation(s) in GBA, which encodes acid beta-glucosidase, were recruited at the SZMC Gaucher Cli
287 gh homology to several other reported fungal beta-glucosidases which are members of the family 3 glyc
288 this cluster shows high sequence homology to beta-glucosidases, which catalyze the hydrolysis of the
290 s niger is known to secrete large amounts of beta-glucosidases, which have a variety of biotechnologi
291 mino acid, membrane-associated lysosomal exo-beta-glucosidase whose defective activity leads to the G
292 glucose tolerance and stimulation of the GH1 beta-glucosidases will be crucial to improve their appli
293 owed highly specific inhibition of mammalian beta-glucosidase with a marked dependence of the potency
294 resulted in the thermo-stabilization of the beta-glucosidase with an increase in optimum temperature
296 e primary and tertiary structures of two GH1 beta-glucosidases with distinct glucose dependence, some
298 o the insoluble substrate only a fraction of beta-glucosidase would be available to the cellulosome.
299 ts of HjCel3A and other structurally similar beta-glucosidases would have a significant economic effe